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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="114">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>214</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>16</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="115">
         <PDBx:B_iso_or_equiv>30.67</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>63.359</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.436</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="116">
         <PDBx:B_iso_or_equiv>31.27</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>62.499</PDBx:Cartn_y>
         <PDBx:Cartn_z>16.515</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="117">
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         <PDBx:Cartn_y>61.522</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.992</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
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         <PDBx:Cartn_y>60.427</PDBx:Cartn_y>
         <PDBx:Cartn_z>16.534</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="119">
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         <PDBx:Cartn_y>63.330</PDBx:Cartn_y>
         <PDBx:Cartn_z>17.702</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>62.522</PDBx:Cartn_y>
         <PDBx:Cartn_z>18.964</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>63.415</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.165</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="122">
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         <PDBx:Cartn_y>62.726</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.207</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="123">
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         <PDBx:Cartn_y>62.824</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.358</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="124">
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         <PDBx:Cartn_x>15.010</PDBx:Cartn_x>
         <PDBx:Cartn_y>63.588</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.540</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_x>15.113</PDBx:Cartn_x>
         <PDBx:Cartn_y>62.161</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.330</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="126">
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         <PDBx:Cartn_x>17.063</PDBx:Cartn_x>
         <PDBx:Cartn_y>61.911</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.932</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>216</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>18</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="127">
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         <PDBx:Cartn_x>16.088</PDBx:Cartn_x>
         <PDBx:Cartn_y>61.030</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.325</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>216</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>18</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="128">
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         <PDBx:Cartn_x>16.270</PDBx:Cartn_x>
         <PDBx:Cartn_y>60.990</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.814</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>216</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>18</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="129">
         <PDBx:B_iso_or_equiv>29.42</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.772</PDBx:Cartn_x>
         <PDBx:Cartn_y>61.854</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.093</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>216</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>18</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>NE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CE3</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE3</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CZ3</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ3</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>221</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>23</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>221</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>221</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>221</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>23</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>221</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>221</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>221</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>237</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>17.398</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>237</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>50.157</PDBx:Cartn_y>
         <PDBx:Cartn_z>18.467</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>237</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>51.374</PDBx:Cartn_y>
         <PDBx:Cartn_z>17.071</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>237</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="312">
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         <PDBx:Cartn_y>53.046</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.256</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>40</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="313">
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         <PDBx:Cartn_y>54.463</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.332</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>40</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>54.693</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.617</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>40</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:Cartn_z>13.257</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>40</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:Cartn_z>13.731</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>14.453</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>238</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>239</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>239</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>240</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>14.701</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>245</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>245</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>245</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>245</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>245</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>255</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>57</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>255</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>255</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>57</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="472">
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>255</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>57</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="473">
         <PDBx:B_iso_or_equiv>19.20</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>4.457</PDBx:Cartn_x>
         <PDBx:Cartn_y>70.063</PDBx:Cartn_y>
         <PDBx:Cartn_z>-2.855</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>255</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>57</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="474">
         <PDBx:B_iso_or_equiv>7.67</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>4.758</PDBx:Cartn_x>
         <PDBx:Cartn_y>68.976</PDBx:Cartn_y>
         <PDBx:Cartn_z>-2.151</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>255</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>57</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="475">
         <PDBx:B_iso_or_equiv>14.33</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>70.564</PDBx:Cartn_y>
         <PDBx:Cartn_z>-3.689</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>255</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>57</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="476">
         <PDBx:B_iso_or_equiv>5.32</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>74.795</PDBx:Cartn_y>
         <PDBx:Cartn_z>1.174</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>58</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="477">
         <PDBx:B_iso_or_equiv>6.58</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>76.248</PDBx:Cartn_y>
         <PDBx:Cartn_z>1.193</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>58</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="478">
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         <PDBx:Cartn_y>76.542</PDBx:Cartn_y>
         <PDBx:Cartn_z>0.771</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>1.003</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>58</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="480">
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         <PDBx:Cartn_z>2.596</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="481">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>2.902</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>ND1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>ND1</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>256</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>294</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>294</PDBx:auth_seq_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>294</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>294</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>294</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>294</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_z>5.120</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>295</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>295</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>295</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>295</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:Cartn_z>3.432</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>295</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>295</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>ND1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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      <PDBx:atom_site id="1067">
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         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>NE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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      <PDBx:atom_site id="1070">
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         <PDBx:Cartn_y>73.133</PDBx:Cartn_y>
         <PDBx:Cartn_z>17.579</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1071">
         <PDBx:B_iso_or_equiv>5.34</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.908</PDBx:Cartn_x>
         <PDBx:Cartn_y>72.642</PDBx:Cartn_y>
         <PDBx:Cartn_z>18.826</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1072">
         <PDBx:B_iso_or_equiv>9.40</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.430</PDBx:Cartn_x>
         <PDBx:Cartn_y>72.530</PDBx:Cartn_y>
         <PDBx:Cartn_z>18.789</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>72.375</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.856</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1074">
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         <PDBx:Cartn_y>71.315</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.339</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1075">
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         <PDBx:Cartn_y>71.410</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.902</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1076">
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         <PDBx:Cartn_y>70.285</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.897</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1077">
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         <PDBx:Cartn_y>68.990</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.235</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>20.851</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>67.745</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.171</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1080">
         <PDBx:B_iso_or_equiv>10.05</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.517</PDBx:Cartn_x>
         <PDBx:Cartn_y>66.686</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.147</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1081">
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         <PDBx:Cartn_x>10.068</PDBx:Cartn_x>
         <PDBx:Cartn_y>72.641</PDBx:Cartn_y>
         <PDBx:Cartn_z>17.614</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>333</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>135</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1082">
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
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         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>NE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:auth_atom_id>NE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE2</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:Cartn_z>23.494</PDBx:Cartn_z>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>22.930</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>22.436</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>175</PDBx:label_seq_id>
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         <PDBx:Cartn_z>23.047</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>21.707</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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      <PDBx:atom_site id="1421">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="1422">
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="1423">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="1424">
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         <PDBx:Cartn_y>78.107</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.177</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>179</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1425">
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         <PDBx:Cartn_y>77.205</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.553</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>179</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1426">
         <PDBx:B_iso_or_equiv>12.16</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.414</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.566</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.275</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>179</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1427">
         <PDBx:B_iso_or_equiv>5.63</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.535</PDBx:Cartn_x>
         <PDBx:Cartn_y>78.815</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.704</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>179</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1428">
         <PDBx:B_iso_or_equiv>9.28</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.354</PDBx:Cartn_x>
         <PDBx:Cartn_y>76.678</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.577</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>179</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1429">
         <PDBx:B_iso_or_equiv>3.77</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.483</PDBx:Cartn_x>
         <PDBx:Cartn_y>76.974</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.404</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>180</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1430">
         <PDBx:B_iso_or_equiv>4.55</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.349</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.700</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.864</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>180</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1431">
         <PDBx:B_iso_or_equiv>7.96</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.054</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.537</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.609</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>180</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1432">
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         <PDBx:Cartn_x>13.024</PDBx:Cartn_x>
         <PDBx:Cartn_y>78.062</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.177</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>180</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1433">
         <PDBx:B_iso_or_equiv>5.25</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.146</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.309</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.382</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>180</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1434">
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         <PDBx:Cartn_x>16.265</PDBx:Cartn_x>
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         <PDBx:Cartn_z>19.461</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>180</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1435">
         <PDBx:B_iso_or_equiv>7.58</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.089</PDBx:Cartn_x>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1436">
         <PDBx:B_iso_or_equiv>6.36</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.459</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.023</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.391</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
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         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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      <PDBx:atom_site id="1715">
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>412</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>412</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>412</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>412</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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      <PDBx:atom_site id="1719">
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_y>89.928</PDBx:Cartn_y>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>87.774</PDBx:Cartn_y>
         <PDBx:Cartn_z>16.460</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_y>87.634</PDBx:Cartn_y>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_x>26.153</PDBx:Cartn_x>
         <PDBx:Cartn_y>88.210</PDBx:Cartn_y>
         <PDBx:Cartn_z>17.373</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>215</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1728">
         <PDBx:B_iso_or_equiv>13.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>25.651</PDBx:Cartn_x>
         <PDBx:Cartn_y>88.970</PDBx:Cartn_y>
         <PDBx:Cartn_z>18.336</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>215</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1729">
         <PDBx:B_iso_or_equiv>11.47</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>27.465</PDBx:Cartn_x>
         <PDBx:Cartn_y>88.031</PDBx:Cartn_y>
         <PDBx:Cartn_z>17.308</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>215</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1730">
         <PDBx:B_iso_or_equiv>8.29</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.750</PDBx:Cartn_x>
         <PDBx:Cartn_y>89.044</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.119</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1731">
         <PDBx:B_iso_or_equiv>8.31</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.433</PDBx:Cartn_x>
         <PDBx:Cartn_y>88.830</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.851</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1732">
         <PDBx:B_iso_or_equiv>11.41</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.014</PDBx:Cartn_x>
         <PDBx:Cartn_y>89.828</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.789</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1733">
         <PDBx:B_iso_or_equiv>9.51</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.461</PDBx:Cartn_x>
         <PDBx:Cartn_y>89.726</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.655</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1734">
         <PDBx:B_iso_or_equiv>9.05</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.253</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.366</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.393</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1735">
         <PDBx:B_iso_or_equiv>5.90</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.786</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.347</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.408</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1736">
         <PDBx:B_iso_or_equiv>9.32</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>26.306</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.489</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.607</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1737">
         <PDBx:B_iso_or_equiv>11.00</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>27.031</PDBx:Cartn_x>
         <PDBx:Cartn_y>85.845</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.510</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1738">
         <PDBx:B_iso_or_equiv>20.77</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>28.331</PDBx:Cartn_x>
         <PDBx:Cartn_y>85.961</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.255</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1739">
         <PDBx:B_iso_or_equiv>11.38</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>29.100</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.739</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.011</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1740">
         <PDBx:B_iso_or_equiv>23.37</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>28.875</PDBx:Cartn_x>
         <PDBx:Cartn_y>85.295</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.249</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>216</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1741">
         <PDBx:B_iso_or_equiv>13.66</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.172</PDBx:Cartn_x>
         <PDBx:Cartn_y>90.812</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.153</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>217</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1742">
         <PDBx:B_iso_or_equiv>15.80</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>22.798</PDBx:Cartn_x>
         <PDBx:Cartn_y>91.827</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.168</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>217</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1743">
         <PDBx:B_iso_or_equiv>21.36</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.901</PDBx:Cartn_x>
         <PDBx:Cartn_y>92.889</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.098</PDBx:Cartn_z>
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         <PDBx:B_iso_or_equiv>11.50</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.745</PDBx:Cartn_x>
         <PDBx:Cartn_y>78.953</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.497</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>441</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>243</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1954">
         <PDBx:B_iso_or_equiv>8.21</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.164</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.575</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.903</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1955">
         <PDBx:B_iso_or_equiv>8.74</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.208</PDBx:Cartn_x>
         <PDBx:Cartn_y>78.126</PDBx:Cartn_y>
         <PDBx:Cartn_z>32.862</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1956">
         <PDBx:B_iso_or_equiv>11.83</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.890</PDBx:Cartn_x>
         <PDBx:Cartn_y>79.222</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.719</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1957">
         <PDBx:B_iso_or_equiv>10.84</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.329</PDBx:Cartn_x>
         <PDBx:Cartn_y>80.305</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.858</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1958">
         <PDBx:B_iso_or_equiv>7.08</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.635</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.023</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.741</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1959">
         <PDBx:B_iso_or_equiv>24.58</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.421</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.426</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.568</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1960">
         <PDBx:B_iso_or_equiv>39.26</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.096</PDBx:Cartn_x>
         <PDBx:Cartn_y>76.318</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.560</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1961">
         <PDBx:B_iso_or_equiv>45.34</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.285</PDBx:Cartn_x>
         <PDBx:Cartn_y>75.912</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.319</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1962">
         <PDBx:B_iso_or_equiv>52.93</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.784</PDBx:Cartn_x>
         <PDBx:Cartn_y>76.582</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.353</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1963">
         <PDBx:B_iso_or_equiv>44.16</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.189</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.685</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.789</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1964">
         <PDBx:B_iso_or_equiv>35.24</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.879</PDBx:Cartn_x>
         <PDBx:Cartn_y>76.153</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.959</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>442</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1965">
         <PDBx:B_iso_or_equiv>9.33</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.115</PDBx:Cartn_x>
         <PDBx:Cartn_y>78.952</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.229</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1966">
         <PDBx:B_iso_or_equiv>8.82</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.886</PDBx:Cartn_x>
         <PDBx:Cartn_y>79.896</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.016</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1967">
         <PDBx:B_iso_or_equiv>9.35</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.994</PDBx:Cartn_x>
         <PDBx:Cartn_y>81.244</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.311</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1968">
         <PDBx:B_iso_or_equiv>11.53</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.729</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.261</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.929</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1969">
         <PDBx:B_iso_or_equiv>10.43</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.268</PDBx:Cartn_x>
         <PDBx:Cartn_y>79.322</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.372</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1970">
         <PDBx:B_iso_or_equiv>12.04</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.190</PDBx:Cartn_x>
         <PDBx:Cartn_y>78.337</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.540</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1971">
         <PDBx:B_iso_or_equiv>21.44</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.555</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.753</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.910</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1972">
         <PDBx:B_iso_or_equiv>33.99</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.644</PDBx:Cartn_x>
         <PDBx:Cartn_y>77.245</PDBx:Cartn_y>
         <PDBx:Cartn_z>38.327</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1973">
         <PDBx:B_iso_or_equiv>46.24</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.803</PDBx:Cartn_x>
         <PDBx:Cartn_y>76.046</PDBx:Cartn_y>
         <PDBx:Cartn_z>38.579</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>443</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>245</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1974">
         <PDBx:B_iso_or_equiv>5.33</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>19.277</PDBx:Cartn_x>
         <PDBx:Cartn_y>81.247</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.009</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1975">
         <PDBx:B_iso_or_equiv>5.08</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>19.458</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.481</PDBx:Cartn_y>
         <PDBx:Cartn_z>32.236</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1976">
         <PDBx:B_iso_or_equiv>7.96</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.127</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.111</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.763</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1977">
         <PDBx:B_iso_or_equiv>7.40</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.923</PDBx:Cartn_x>
         <PDBx:Cartn_y>84.310</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.928</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1978">
         <PDBx:B_iso_or_equiv>6.81</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.388</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.197</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.014</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1979">
         <PDBx:B_iso_or_equiv>6.39</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.253</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.275</PDBx:Cartn_y>
         <PDBx:Cartn_z>29.956</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1980">
         <PDBx:B_iso_or_equiv>6.94</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.849</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.017</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.436</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1981">
         <PDBx:B_iso_or_equiv>4.93</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.259</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.311</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.133</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>247</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1982">
         <PDBx:B_iso_or_equiv>4.82</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.068</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.819</PDBx:Cartn_y>
         <PDBx:Cartn_z>30.464</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>247</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1983">
         <PDBx:B_iso_or_equiv>8.54</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.930</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.138</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.453</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>247</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1984">
         <PDBx:B_iso_or_equiv>8.38</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.199</PDBx:Cartn_x>
         <PDBx:Cartn_y>84.106</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.265</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>247</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1985">
         <PDBx:B_iso_or_equiv>6.92</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.643</PDBx:Cartn_x>
         <PDBx:Cartn_y>81.838</PDBx:Cartn_y>
         <PDBx:Cartn_z>29.338</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>247</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1986">
         <PDBx:B_iso_or_equiv>7.23</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.325</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.228</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.655</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>247</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1987">
         <PDBx:B_iso_or_equiv>6.48</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.763</PDBx:Cartn_x>
         <PDBx:Cartn_y>81.651</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.321</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>247</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1988">
         <PDBx:B_iso_or_equiv>8.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.782</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.300</PDBx:Cartn_y>
         <PDBx:Cartn_z>32.479</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1989">
         <PDBx:B_iso_or_equiv>7.75</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.712</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.401</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.476</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1990">
         <PDBx:B_iso_or_equiv>12.20</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.079</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.145</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.754</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1991">
         <PDBx:B_iso_or_equiv>12.98</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.227</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.847</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.323</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1992">
         <PDBx:B_iso_or_equiv>8.22</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.200</PDBx:Cartn_x>
         <PDBx:Cartn_y>81.001</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.803</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1993">
         <PDBx:B_iso_or_equiv>10.63</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.449</PDBx:Cartn_x>
         <PDBx:Cartn_y>80.157</PDBx:Cartn_y>
         <PDBx:Cartn_z>32.396</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>SG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>SG</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1994">
         <PDBx:B_iso_or_equiv>9.12</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.274</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.876</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.291</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1995">
         <PDBx:B_iso_or_equiv>8.98</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.687</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.444</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.586</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1996">
         <PDBx:B_iso_or_equiv>10.97</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.338</PDBx:Cartn_x>
         <PDBx:Cartn_y>84.784</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.435</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1997">
         <PDBx:B_iso_or_equiv>8.91</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.931</PDBx:Cartn_x>
         <PDBx:Cartn_y>85.757</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.068</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1998">
         <PDBx:B_iso_or_equiv>9.84</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.601</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.461</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.341</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1999">
         <PDBx:B_iso_or_equiv>14.87</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.887</PDBx:Cartn_x>
         <PDBx:Cartn_y>81.210</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.815</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2000">
         <PDBx:B_iso_or_equiv>28.12</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>80.481</PDBx:Cartn_y>
         <PDBx:Cartn_z>38.875</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
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      <PDBx:atom_site id="2001">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="2003">
         <PDBx:B_iso_or_equiv>8.23</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>84.844</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.612</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2004">
         <PDBx:B_iso_or_equiv>8.24</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>86.096</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.345</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
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      <PDBx:atom_site id="2005">
         <PDBx:B_iso_or_equiv>11.20</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>86.899</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.340</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
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      <PDBx:atom_site id="2006">
         <PDBx:B_iso_or_equiv>11.63</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>88.092</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.186</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
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      <PDBx:atom_site id="2007">
         <PDBx:B_iso_or_equiv>7.92</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>85.868</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.838</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
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      <PDBx:atom_site id="2008">
         <PDBx:B_iso_or_equiv>10.63</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.348</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.009</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.303</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2009">
         <PDBx:B_iso_or_equiv>16.45</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.785</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.995</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.849</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2010">
         <PDBx:B_iso_or_equiv>11.51</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>22.405</PDBx:Cartn_x>
         <PDBx:Cartn_y>88.062</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.732</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2011">
         <PDBx:B_iso_or_equiv>5.45</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>22.339</PDBx:Cartn_x>
         <PDBx:Cartn_y>85.804</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.545</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>250</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2012">
         <PDBx:B_iso_or_equiv>7.69</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.334</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.223</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.619</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>251</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2013">
         <PDBx:B_iso_or_equiv>6.70</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.427</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.845</PDBx:Cartn_y>
         <PDBx:Cartn_z>32.665</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>251</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2014">
         <PDBx:B_iso_or_equiv>10.58</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.144</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.638</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.567</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>251</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2015">
         <PDBx:B_iso_or_equiv>12.52</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>88.691</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.155</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:B_iso_or_equiv>9.49</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>87.718</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.413</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>251</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2017">
         <PDBx:B_iso_or_equiv>14.22</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.515</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.921</PDBx:Cartn_y>
         <PDBx:Cartn_z>34.374</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="2019">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>35.615</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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      <PDBx:atom_site id="2021">
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         <PDBx:Cartn_z>31.110</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>252</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2022">
         <PDBx:B_iso_or_equiv>6.34</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>87.723</PDBx:Cartn_y>
         <PDBx:Cartn_z>30.009</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>252</PDBx:label_seq_id>
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      <PDBx:atom_site id="2023">
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         <PDBx:Cartn_y>87.098</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.703</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>252</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2024">
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         <PDBx:Cartn_z>28.672</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2025">
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         <PDBx:Cartn_z>30.150</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2026">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>252</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2027">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>253</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>88.527</PDBx:Cartn_y>
         <PDBx:Cartn_z>25.866</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>253</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2033">
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         <PDBx:Cartn_z>25.767</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="2034">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>253</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2037">
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         <PDBx:Cartn_x>12.960</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.097</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.160</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>253</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2038">
         <PDBx:B_iso_or_equiv>7.21</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>85.712</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.944</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>253</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2039">
         <PDBx:B_iso_or_equiv>6.89</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>86.032</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.614</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>253</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2040">
         <PDBx:B_iso_or_equiv>5.90</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.841</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.417</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.140</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>254</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2041">
         <PDBx:B_iso_or_equiv>6.60</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>19.957</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.854</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.301</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>254</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2042">
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         <PDBx:Cartn_y>89.398</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.267</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>254</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2043">
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         <PDBx:Cartn_y>90.081</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.283</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>254</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2044">
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         <PDBx:Cartn_x>19.600</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.266</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.945</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>254</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2045">
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         <PDBx:Cartn_x>18.776</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.079</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.255</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>254</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>254</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>23.284</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>453</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>255</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2048">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>453</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>453</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2083">
         <PDBx:B_iso_or_equiv>41.52</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_z>15.869</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2084">
         <PDBx:B_iso_or_equiv>49.63</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>25.905</PDBx:Cartn_x>
         <PDBx:Cartn_y>98.294</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.788</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2085">
         <PDBx:B_iso_or_equiv>58.48</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>25.756</PDBx:Cartn_x>
         <PDBx:Cartn_y>96.914</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.329</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2086">
         <PDBx:B_iso_or_equiv>71.39</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.960</PDBx:Cartn_x>
         <PDBx:Cartn_y>96.538</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.332</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2087">
         <PDBx:B_iso_or_equiv>58.09</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.238</PDBx:Cartn_x>
         <PDBx:Cartn_y>97.436</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.673</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2088">
         <PDBx:B_iso_or_equiv>53.07</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.881</PDBx:Cartn_x>
         <PDBx:Cartn_y>95.259</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.985</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2089">
         <PDBx:B_iso_or_equiv>23.84</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.188</PDBx:Cartn_x>
         <PDBx:Cartn_y>98.884</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.985</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2090">
         <PDBx:B_iso_or_equiv>23.46</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.088</PDBx:Cartn_x>
         <PDBx:Cartn_y>98.315</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.208</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2091">
         <PDBx:B_iso_or_equiv>30.90</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.954</PDBx:Cartn_x>
         <PDBx:Cartn_y>99.348</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.194</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2092">
         <PDBx:B_iso_or_equiv>31.08</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.042</PDBx:Cartn_x>
         <PDBx:Cartn_y>99.244</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.374</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2093">
         <PDBx:B_iso_or_equiv>20.81</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>19.624</PDBx:Cartn_x>
         <PDBx:Cartn_y>96.951</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.780</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2094">
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         <PDBx:Cartn_x>20.540</PDBx:Cartn_x>
         <PDBx:Cartn_y>95.794</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.486</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2095">
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         <PDBx:Cartn_x>21.737</PDBx:Cartn_x>
         <PDBx:Cartn_y>95.831</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.832</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2096">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2098">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
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         <PDBx:label_seq_id>267</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>14.197</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>15.326</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:Cartn_y>100.164</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.931</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>101.208</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.661</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>102.528</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.790</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>103.022</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.514</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>103.841</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.688</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>104.262</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.979</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>104.241</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.561</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>97.626</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.081</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>268</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>96.807</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.926</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>13.435</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>268</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>94.875</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.287</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>268</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2161">
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         <PDBx:Cartn_x>10.875</PDBx:Cartn_x>
         <PDBx:Cartn_y>96.848</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.476</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>268</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_x>9.750</PDBx:Cartn_x>
         <PDBx:Cartn_y>95.831</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.274</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>268</PDBx:label_seq_id>
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         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>273</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2200">
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         <PDBx:Cartn_y>90.690</PDBx:Cartn_y>
         <PDBx:Cartn_z>17.213</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>SD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>SD</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>S</PDBx:type_symbol>
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      <PDBx:atom_site id="2201">
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         <PDBx:Cartn_y>91.126</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.511</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>273</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2202">
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         <PDBx:Cartn_y>91.668</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.447</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2203">
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         <PDBx:Cartn_y>92.021</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.769</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2204">
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         <PDBx:Cartn_y>91.575</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.030</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2205">
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         <PDBx:Cartn_x>9.786</PDBx:Cartn_x>
         <PDBx:Cartn_y>91.049</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.109</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2206">
         <PDBx:B_iso_or_equiv>9.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.722</PDBx:Cartn_x>
         <PDBx:Cartn_y>93.520</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.040</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2207">
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         <PDBx:Cartn_y>93.903</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.135</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2208">
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         <PDBx:Cartn_y>95.386</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.399</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2209">
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         <PDBx:Cartn_y>95.807</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.331</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2210">
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         <PDBx:Cartn_x>15.178</PDBx:Cartn_x>
         <PDBx:Cartn_y>97.076</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.272</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2211">
         <PDBx:B_iso_or_equiv>60.12</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.289</PDBx:Cartn_x>
         <PDBx:Cartn_y>98.062</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.259</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2212">
         <PDBx:B_iso_or_equiv>58.39</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>97.366</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.215</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>274</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2213">
         <PDBx:B_iso_or_equiv>6.49</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.180</PDBx:Cartn_x>
         <PDBx:Cartn_y>91.665</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.011</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>275</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2214">
         <PDBx:B_iso_or_equiv>7.09</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.781</PDBx:Cartn_x>
         <PDBx:Cartn_y>91.288</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.175</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>275</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2215">
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         <PDBx:Cartn_x>7.540</PDBx:Cartn_x>
         <PDBx:Cartn_y>89.784</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.006</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>275</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2216">
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         <PDBx:Cartn_y>89.347</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.089</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>275</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2217">
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         <PDBx:Cartn_y>92.129</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.280</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>275</PDBx:label_seq_id>
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      <PDBx:atom_site id="2218">
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         <PDBx:Cartn_y>93.567</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.766</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>275</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2219">
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         <PDBx:Cartn_x>6.269</PDBx:Cartn_x>
         <PDBx:Cartn_y>94.608</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.799</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>275</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2220">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>473</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>474</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>474</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>SG</PDBx:auth_atom_id>
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         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>282</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2276">
         <PDBx:B_iso_or_equiv>9.47</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>87.940</PDBx:Cartn_y>
         <PDBx:Cartn_z>25.552</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>481</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>283</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2277">
         <PDBx:B_iso_or_equiv>8.58</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>89.256</PDBx:Cartn_y>
         <PDBx:Cartn_z>25.078</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>481</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>283</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2278">
         <PDBx:B_iso_or_equiv>12.68</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>89.166</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.727</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>481</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>283</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2279">
         <PDBx:B_iso_or_equiv>12.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.658</PDBx:Cartn_x>
         <PDBx:Cartn_y>90.146</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.979</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>481</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>283</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2280">
         <PDBx:B_iso_or_equiv>9.08</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>89.926</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.140</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>481</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>283</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2281">
         <PDBx:B_iso_or_equiv>9.62</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.131</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.974</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.393</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2282">
         <PDBx:B_iso_or_equiv>8.73</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.891</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.808</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.162</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2283">
         <PDBx:B_iso_or_equiv>10.36</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.076</PDBx:Cartn_x>
         <PDBx:Cartn_y>88.038</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.915</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2284">
         <PDBx:B_iso_or_equiv>10.17</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>1.893</PDBx:Cartn_x>
         <PDBx:Cartn_y>87.711</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.878</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="2285">
         <PDBx:B_iso_or_equiv>8.53</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>4.539</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.427</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.114</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2286">
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         <PDBx:Cartn_x>5.611</PDBx:Cartn_x>
         <PDBx:Cartn_y>86.254</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.172</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2287">
         <PDBx:B_iso_or_equiv>5.85</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.076</PDBx:Cartn_x>
         <PDBx:Cartn_y>84.832</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.236</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2288">
         <PDBx:B_iso_or_equiv>8.61</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.699</PDBx:Cartn_x>
         <PDBx:Cartn_y>84.567</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.529</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="2289">
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         <PDBx:Cartn_x>6.788</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.363</PDBx:Cartn_y>
         <PDBx:Cartn_z>25.074</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="2290">
         <PDBx:B_iso_or_equiv>6.58</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.283</PDBx:Cartn_x>
         <PDBx:Cartn_y>82.303</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.446</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>284</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2291">
         <PDBx:B_iso_or_equiv>13.13</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.356</PDBx:Cartn_x>
         <PDBx:Cartn_y>83.209</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.263</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>482</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>12.152</PDBx:Cartn_z>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>1</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.2183</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0723</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>1</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2410</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.2343</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.0897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>1</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="5">
         <PDBx:U11>0.1438</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1378</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="6">
         <PDBx:U11>0.1437</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1428</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="7">
         <PDBx:U11>0.1925</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>0.0079</PDBx:U13>
         <PDBx:U22>0.1933</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.0580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="8">
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         <PDBx:U12>-0.0149</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.2147</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.0595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="9">
         <PDBx:U11>0.2799</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.2809</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="10">
         <PDBx:U11>0.2549</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.2550</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="11">
         <PDBx:U11>0.2755</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.2748</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="12">
         <PDBx:U11>0.1584</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1563</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="13">
         <PDBx:U11>0.1514</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.1500</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="14">
         <PDBx:U11>0.1967</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.1962</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1979</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.2010</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.0609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="16">
         <PDBx:U11>0.1736</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.1693</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1881</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1843</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.0712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1637</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1589</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="19">
         <PDBx:U11>0.3853</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.3796</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.2229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="20">
         <PDBx:U11>0.1296</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1256</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>202</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="21">
         <PDBx:U11>0.1392</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1356</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.0600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>202</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="22">
         <PDBx:U11>0.1995</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.2002</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.0700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>202</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="23">
         <PDBx:U11>0.2017</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.2060</PDBx:U22>
         <PDBx:U23>-0.0178</PDBx:U23>
         <PDBx:U33>0.0665</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>202</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="24">
         <PDBx:U11>0.1500</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.1402</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.0600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>202</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="25">
         <PDBx:U11>0.1820</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1835</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.0702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="26">
         <PDBx:U11>0.1907</PDBx:U11>
         <PDBx:U12>-0.0079</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1971</PDBx:U22>
         <PDBx:U23>-0.0172</PDBx:U23>
         <PDBx:U33>0.0732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="27">
         <PDBx:U11>0.2315</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.2444</PDBx:U22>
         <PDBx:U23>-0.0226</PDBx:U23>
         <PDBx:U33>0.0952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="28">
         <PDBx:U11>0.2376</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.2557</PDBx:U22>
         <PDBx:U23>-0.0281</PDBx:U23>
         <PDBx:U33>0.1065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="29">
         <PDBx:U11>0.2163</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.2210</PDBx:U22>
         <PDBx:U23>-0.0196</PDBx:U23>
         <PDBx:U33>0.0777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="30">
         <PDBx:U11>0.2662</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.2726</PDBx:U22>
         <PDBx:U23>-0.0167</PDBx:U23>
         <PDBx:U33>0.1240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="31">
         <PDBx:U11>0.3387</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.3449</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.1976</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="32">
         <PDBx:U11>0.4971</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.5070</PDBx:U22>
         <PDBx:U23>-0.0172</PDBx:U23>
         <PDBx:U33>0.3545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="33">
         <PDBx:U11>0.6967</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.7049</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.5515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="34">
         <PDBx:U11>0.4492</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.4516</PDBx:U22>
         <PDBx:U23>-0.0134</PDBx:U23>
         <PDBx:U33>0.3018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="35">
         <PDBx:U11>0.5440</PDBx:U11>
         <PDBx:U12>-0.0188</PDBx:U12>
         <PDBx:U13>0.0138</PDBx:U13>
         <PDBx:U22>0.5561</PDBx:U22>
         <PDBx:U23>-0.0147</PDBx:U23>
         <PDBx:U33>0.3977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="36">
         <PDBx:U11>0.1665</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.1794</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.0664</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="37">
         <PDBx:U11>0.1612</PDBx:U11>
         <PDBx:U12>-0.0196</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.1785</PDBx:U22>
         <PDBx:U23>-0.0154</PDBx:U23>
         <PDBx:U33>0.0624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="38">
         <PDBx:U11>0.1994</PDBx:U11>
         <PDBx:U12>-0.0198</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.2165</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.0567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="39">
         <PDBx:U11>0.2057</PDBx:U11>
         <PDBx:U12>-0.0242</PDBx:U12>
         <PDBx:U13>0.0143</PDBx:U13>
         <PDBx:U22>0.2245</PDBx:U22>
         <PDBx:U23>-0.0215</PDBx:U23>
         <PDBx:U33>0.0600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="40">
         <PDBx:U11>0.2604</PDBx:U11>
         <PDBx:U12>-0.0220</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.2755</PDBx:U22>
         <PDBx:U23>-0.0161</PDBx:U23>
         <PDBx:U33>0.1122</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="41">
         <PDBx:U11>0.2401</PDBx:U11>
         <PDBx:U12>-0.0202</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.2501</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.0877</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="42">
         <PDBx:U11>0.2807</PDBx:U11>
         <PDBx:U12>-0.0216</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.2960</PDBx:U22>
         <PDBx:U23>-0.0156</PDBx:U23>
         <PDBx:U33>0.1330</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="43">
         <PDBx:U11>0.1006</PDBx:U11>
         <PDBx:U12>-0.0163</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.1163</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.0436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="44">
         <PDBx:U11>0.0748</PDBx:U11>
         <PDBx:U12>-0.0167</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.0913</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="45">
         <PDBx:U11>0.1288</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1502</PDBx:U22>
         <PDBx:U23>-0.0182</PDBx:U23>
         <PDBx:U33>0.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="46">
         <PDBx:U11>0.1106</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.1319</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.0440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="47">
         <PDBx:U11>0.0939</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1037</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.0434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="48">
         <PDBx:U11>0.1021</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1077</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.0554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="49">
         <PDBx:U11>0.1028</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.1130</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="50">
         <PDBx:U11>0.0865</PDBx:U11>
         <PDBx:U12>-0.0130</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.0873</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="51">
         <PDBx:U11>0.0551</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.0838</PDBx:U22>
         <PDBx:U23>-0.0099</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="52">
         <PDBx:U11>0.0557</PDBx:U11>
         <PDBx:U12>-0.0181</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.0926</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.0416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="53">
         <PDBx:U11>0.0888</PDBx:U11>
         <PDBx:U12>-0.0162</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.1227</PDBx:U22>
         <PDBx:U23>-0.0205</PDBx:U23>
         <PDBx:U33>0.0441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="54">
         <PDBx:U11>0.0974</PDBx:U11>
         <PDBx:U12>-0.0199</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.1293</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.0466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="55">
         <PDBx:U11>0.0933</PDBx:U11>
         <PDBx:U12>-0.0238</PDBx:U12>
         <PDBx:U13>0.0097</PDBx:U13>
         <PDBx:U22>0.1374</PDBx:U22>
         <PDBx:U23>-0.0270</PDBx:U23>
         <PDBx:U33>0.0469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="56">
         <PDBx:U11>0.0803</PDBx:U11>
         <PDBx:U12>-0.0230</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.1348</PDBx:U22>
         <PDBx:U23>-0.0308</PDBx:U23>
         <PDBx:U33>0.0483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="57">
         <PDBx:U11>0.0858</PDBx:U11>
         <PDBx:U12>-0.0257</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.1319</PDBx:U22>
         <PDBx:U23>-0.0261</PDBx:U23>
         <PDBx:U33>0.0458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="58">
         <PDBx:U11>0.0539</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.0904</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.0417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="59">
         <PDBx:U11>0.0692</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.1042</PDBx:U22>
         <PDBx:U23>-0.0163</PDBx:U23>
         <PDBx:U33>0.0468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="60">
         <PDBx:U11>0.1144</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1567</PDBx:U22>
         <PDBx:U23>-0.0337</PDBx:U23>
         <PDBx:U33>0.0549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="61">
         <PDBx:U11>0.0993</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1497</PDBx:U22>
         <PDBx:U23>-0.0368</PDBx:U23>
         <PDBx:U33>0.0524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="62">
         <PDBx:U11>0.0823</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1116</PDBx:U22>
         <PDBx:U23>-0.0168</PDBx:U23>
         <PDBx:U33>0.0523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="63">
         <PDBx:U11>0.1489</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.1654</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.0661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="64">
         <PDBx:U11>0.1727</PDBx:U11>
         <PDBx:U12>0.0053</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.1824</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.0685</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="65">
         <PDBx:U11>0.2209</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.2319</PDBx:U22>
         <PDBx:U23>-0.0265</PDBx:U23>
         <PDBx:U33>0.0887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="66">
         <PDBx:U11>0.0585</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1051</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.0440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="67">
         <PDBx:U11>0.0621</PDBx:U11>
         <PDBx:U12>-0.0205</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.1183</PDBx:U22>
         <PDBx:U23>-0.0257</PDBx:U23>
         <PDBx:U33>0.0482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="84">
         <PDBx:U11>0.0873</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1291</PDBx:U22>
         <PDBx:U23>-0.0270</PDBx:U23>
         <PDBx:U33>0.0521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="85">
         <PDBx:U11>0.0907</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1237</PDBx:U22>
         <PDBx:U23>-0.0225</PDBx:U23>
         <PDBx:U33>0.0527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="86">
         <PDBx:U11>0.1499</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1803</PDBx:U22>
         <PDBx:U23>-0.0335</PDBx:U23>
         <PDBx:U33>0.0699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="87">
         <PDBx:U11>0.1317</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1696</PDBx:U22>
         <PDBx:U23>-0.0370</PDBx:U23>
         <PDBx:U33>0.0613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="88">
         <PDBx:U11>0.1370</PDBx:U11>
         <PDBx:U12>0.0098</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1665</PDBx:U22>
         <PDBx:U23>-0.0356</PDBx:U23>
         <PDBx:U33>0.0661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="89">
         <PDBx:U11>0.2641</PDBx:U11>
         <PDBx:U12>0.0118</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.2823</PDBx:U22>
         <PDBx:U23>-0.0428</PDBx:U23>
         <PDBx:U33>0.1477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="90">
         <PDBx:U11>0.1228</PDBx:U11>
         <PDBx:U12>-0.0014</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1478</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.0632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="91">
         <PDBx:U11>0.1338</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1581</PDBx:U22>
         <PDBx:U23>-0.0224</PDBx:U23>
         <PDBx:U33>0.0654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="92">
         <PDBx:U11>0.2428</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.2593</PDBx:U22>
         <PDBx:U23>-0.0328</PDBx:U23>
         <PDBx:U33>0.1119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="93">
         <PDBx:U11>0.2652</PDBx:U11>
         <PDBx:U12>-0.0025</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.2822</PDBx:U22>
         <PDBx:U23>-0.0328</PDBx:U23>
         <PDBx:U33>0.1329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="94">
         <PDBx:U11>0.1799</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1990</PDBx:U22>
         <PDBx:U23>-0.0263</PDBx:U23>
         <PDBx:U33>0.0734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="95">
         <PDBx:U11>0.1979</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.2089</PDBx:U22>
         <PDBx:U23>-0.0218</PDBx:U23>
         <PDBx:U33>0.0761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="96">
         <PDBx:U11>0.1942</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.2177</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.0683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="97">
         <PDBx:U11>0.2547</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.2610</PDBx:U22>
         <PDBx:U23>-0.0203</PDBx:U23>
         <PDBx:U33>0.1077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="98">
         <PDBx:U11>0.2009</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.2134</PDBx:U22>
         <PDBx:U23>-0.0283</PDBx:U23>
         <PDBx:U33>0.0795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>212</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="99">
         <PDBx:U11>0.2117</PDBx:U11>
         <PDBx:U12>0.0060</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.2194</PDBx:U22>
         <PDBx:U23>-0.0274</PDBx:U23>
         <PDBx:U33>0.0779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>212</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="100">
         <PDBx:U11>0.3213</PDBx:U11>
         <PDBx:U12>0.0101</PDBx:U12>
         <PDBx:U13>-0.0092</PDBx:U13>
         <PDBx:U22>0.3235</PDBx:U22>
         <PDBx:U23>-0.0255</PDBx:U23>
         <PDBx:U33>0.1860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>212</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="101">
         <PDBx:U11>0.3247</PDBx:U11>
         <PDBx:U12>0.0105</PDBx:U12>
         <PDBx:U13>-0.0099</PDBx:U13>
         <PDBx:U22>0.3238</PDBx:U22>
         <PDBx:U23>-0.0235</PDBx:U23>
         <PDBx:U33>0.1877</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>212</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="102">
         <PDBx:U11>0.3321</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.3325</PDBx:U22>
         <PDBx:U23>-0.0261</PDBx:U23>
         <PDBx:U33>0.1965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="103">
         <PDBx:U11>0.3573</PDBx:U11>
         <PDBx:U12>0.0161</PDBx:U12>
         <PDBx:U13>-0.0173</PDBx:U13>
         <PDBx:U22>0.3507</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.2185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="104">
         <PDBx:U11>0.4646</PDBx:U11>
         <PDBx:U12>0.0156</PDBx:U12>
         <PDBx:U13>-0.0175</PDBx:U13>
         <PDBx:U22>0.4528</PDBx:U22>
         <PDBx:U23>-0.0198</PDBx:U23>
         <PDBx:U33>0.3198</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="105">
         <PDBx:U11>0.4775</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>-0.0190</PDBx:U13>
         <PDBx:U22>0.4670</PDBx:U22>
         <PDBx:U23>-0.0216</PDBx:U23>
         <PDBx:U33>0.3337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="106">
         <PDBx:U11>0.3987</PDBx:U11>
         <PDBx:U12>0.0201</PDBx:U12>
         <PDBx:U13>-0.0224</PDBx:U13>
         <PDBx:U22>0.3942</PDBx:U22>
         <PDBx:U23>-0.0299</PDBx:U23>
         <PDBx:U33>0.2651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="107">
         <PDBx:U11>0.5644</PDBx:U11>
         <PDBx:U12>0.0215</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.5615</PDBx:U22>
         <PDBx:U23>-0.0332</PDBx:U23>
         <PDBx:U33>0.4350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="108">
         <PDBx:U11>0.6592</PDBx:U11>
         <PDBx:U12>0.0264</PDBx:U12>
         <PDBx:U13>-0.0303</PDBx:U13>
         <PDBx:U22>0.6571</PDBx:U22>
         <PDBx:U23>-0.0391</PDBx:U23>
         <PDBx:U33>0.5351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="109">
         <PDBx:U11>0.7868</PDBx:U11>
         <PDBx:U12>0.0298</PDBx:U12>
         <PDBx:U13>-0.0364</PDBx:U13>
         <PDBx:U22>0.7737</PDBx:U22>
         <PDBx:U23>-0.0359</PDBx:U23>
         <PDBx:U33>0.6567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="110">
         <PDBx:U11>0.9375</PDBx:U11>
         <PDBx:U12>0.0351</PDBx:U12>
         <PDBx:U13>-0.0436</PDBx:U13>
         <PDBx:U22>0.9242</PDBx:U22>
         <PDBx:U23>-0.0417</PDBx:U23>
         <PDBx:U33>0.8122</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="111">
         <PDBx:U11>0.4494</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>-0.0158</PDBx:U13>
         <PDBx:U22>0.4326</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.2990</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>214</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="112">
         <PDBx:U11>0.4549</PDBx:U11>
         <PDBx:U12>0.0125</PDBx:U12>
         <PDBx:U13>-0.0153</PDBx:U13>
         <PDBx:U22>0.4338</PDBx:U22>
         <PDBx:U23>-0.0108</PDBx:U23>
         <PDBx:U33>0.2990</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>214</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="113">
         <PDBx:U11>0.4934</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>-0.0194</PDBx:U13>
         <PDBx:U22>0.4640</PDBx:U22>
         <PDBx:U23>-0.0086</PDBx:U23>
         <PDBx:U33>0.3311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>214</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="114">
         <PDBx:U11>0.4720</PDBx:U11>
         <PDBx:U12>0.0161</PDBx:U12>
         <PDBx:U13>-0.0235</PDBx:U13>
         <PDBx:U22>0.4396</PDBx:U22>
         <PDBx:U23>-0.0100</PDBx:U23>
         <PDBx:U33>0.3096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>214</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="115">
         <PDBx:U11>0.4555</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>-0.0183</PDBx:U13>
         <PDBx:U22>0.4223</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.2876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="116">
         <PDBx:U11>0.4686</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>-0.0216</PDBx:U13>
         <PDBx:U22>0.4267</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.2926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="117">
         <PDBx:U11>0.5115</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>-0.0212</PDBx:U13>
         <PDBx:U22>0.4651</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.3315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="118">
         <PDBx:U11>0.5127</PDBx:U11>
         <PDBx:U12>0.0102</PDBx:U12>
         <PDBx:U13>-0.0249</PDBx:U13>
         <PDBx:U22>0.4584</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.3263</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="119">
         <PDBx:U11>0.4718</PDBx:U11>
         <PDBx:U12>0.0086</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.4283</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.2911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="120">
         <PDBx:U11>0.6447</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0238</PDBx:U13>
         <PDBx:U22>0.5919</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.4546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="121">
         <PDBx:U11>0.7978</PDBx:U11>
         <PDBx:U12>0.0049</PDBx:U12>
         <PDBx:U13>-0.0222</PDBx:U13>
         <PDBx:U22>0.7447</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.6041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="122">
         <PDBx:U11>0.9216</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>-0.0237</PDBx:U13>
         <PDBx:U22>0.8596</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.7171</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="123">
         <PDBx:U11>1.0787</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>-0.0198</PDBx:U13>
         <PDBx:U22>1.0160</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.8705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="124">
         <PDBx:U11>0.9080</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.8526</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.7063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="125">
         <PDBx:U11>0.8861</PDBx:U11>
         <PDBx:U12>-0.0064</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>0.8151</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.6673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="126">
         <PDBx:U11>0.4591</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>-0.0170</PDBx:U13>
         <PDBx:U22>0.4173</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.2825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="127">
         <PDBx:U11>0.4626</PDBx:U11>
         <PDBx:U12>0.0073</PDBx:U12>
         <PDBx:U13>-0.0162</PDBx:U13>
         <PDBx:U22>0.4179</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.2834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="128">
         <PDBx:U11>0.4501</PDBx:U11>
         <PDBx:U12>0.0083</PDBx:U12>
         <PDBx:U13>-0.0145</PDBx:U13>
         <PDBx:U22>0.4112</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="129">
         <PDBx:U11>0.4405</PDBx:U11>
         <PDBx:U12>0.0069</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.4065</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.2709</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="130">
         <PDBx:U11>0.5017</PDBx:U11>
         <PDBx:U12>0.0037</PDBx:U12>
         <PDBx:U13>-0.0130</PDBx:U13>
         <PDBx:U22>0.4555</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.3179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="131">
         <PDBx:U11>0.5422</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.4881</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.3494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="132">
         <PDBx:U11>0.6000</PDBx:U11>
         <PDBx:U12>0.0021</PDBx:U12>
         <PDBx:U13>-0.0192</PDBx:U13>
         <PDBx:U22>0.5376</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.4011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="133">
         <PDBx:U11>0.5838</PDBx:U11>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>218</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>218</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:U33>0.5438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>218</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="150">
         <PDBx:U11>0.1144</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.1091</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="151">
         <PDBx:U11>0.0791</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.0769</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="152">
         <PDBx:U11>0.1559</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1597</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.0589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="153">
         <PDBx:U11>0.1642</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1727</PDBx:U22>
         <PDBx:U23>-0.0194</PDBx:U23>
         <PDBx:U33>0.0660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="154">
         <PDBx:U11>0.1282</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1244</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.0550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="155">
         <PDBx:U11>0.1239</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1203</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.0542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="156">
         <PDBx:U11>0.1345</PDBx:U11>
         <PDBx:U12>0.0029</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1251</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.0530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="157">
         <PDBx:U11>0.0807</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.0865</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="158">
         <PDBx:U11>0.0772</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.0901</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.0445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="159">
         <PDBx:U11>0.1391</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1505</PDBx:U22>
         <PDBx:U23>-0.0165</PDBx:U23>
         <PDBx:U33>0.0466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="160">
         <PDBx:U11>0.1156</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1220</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.0438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="161">
         <PDBx:U11>0.0628</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.0764</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.0421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="162">
         <PDBx:U11>0.0994</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1115</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.0505</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="163">
         <PDBx:U11>0.1471</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>-0.0061</PDBx:U13>
         <PDBx:U22>0.1502</PDBx:U22>
         <PDBx:U23>-0.0186</PDBx:U23>
         <PDBx:U33>0.0545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="164">
         <PDBx:U11>0.0941</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1134</PDBx:U22>
         <PDBx:U23>-0.0169</PDBx:U23>
         <PDBx:U33>0.0518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="165">
         <PDBx:U11>0.1487</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.1517</PDBx:U22>
         <PDBx:U23>-0.0222</PDBx:U23>
         <PDBx:U33>0.0572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="166">
         <PDBx:U11>0.1675</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.1779</PDBx:U22>
         <PDBx:U23>-0.0329</PDBx:U23>
         <PDBx:U33>0.0621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="167">
         <PDBx:U11>0.0968</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1262</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.0559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="168">
         <PDBx:U11>0.1670</PDBx:U11>
         <PDBx:U12>0.0157</PDBx:U12>
         <PDBx:U13>-0.0146</PDBx:U13>
         <PDBx:U22>0.1811</PDBx:U22>
         <PDBx:U23>-0.0399</PDBx:U23>
         <PDBx:U33>0.0664</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="169">
         <PDBx:U11>0.1254</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1588</PDBx:U22>
         <PDBx:U23>-0.0349</PDBx:U23>
         <PDBx:U33>0.0670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="170">
         <PDBx:U11>0.1380</PDBx:U11>
         <PDBx:U12>0.0143</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.1651</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.0706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="171">
         <PDBx:U11>0.0908</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1096</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="172">
         <PDBx:U11>0.0912</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.1095</PDBx:U22>
         <PDBx:U23>-0.0126</PDBx:U23>
         <PDBx:U33>0.0408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="173">
         <PDBx:U11>0.1051</PDBx:U11>
         <PDBx:U12>-0.0179</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.1262</PDBx:U22>
         <PDBx:U23>-0.0157</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="174">
         <PDBx:U11>0.0566</PDBx:U11>
         <PDBx:U12>-0.0175</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.0865</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.0406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="175">
         <PDBx:U11>0.1304</PDBx:U11>
         <PDBx:U12>-0.0218</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.1535</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="176">
         <PDBx:U11>0.1921</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>0.0160</PDBx:U13>
         <PDBx:U22>0.2125</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.0611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="177">
         <PDBx:U11>0.2654</PDBx:U11>
         <PDBx:U12>-0.0330</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.2880</PDBx:U22>
         <PDBx:U23>-0.0357</PDBx:U23>
         <PDBx:U33>0.1160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="178">
         <PDBx:U11>0.2180</PDBx:U11>
         <PDBx:U12>-0.0335</PDBx:U12>
         <PDBx:U13>0.0210</PDBx:U13>
         <PDBx:U22>0.2504</PDBx:U22>
         <PDBx:U23>-0.0438</PDBx:U23>
         <PDBx:U33>0.0795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="179">
         <PDBx:U11>0.4022</PDBx:U11>
         <PDBx:U12>-0.0373</PDBx:U12>
         <PDBx:U13>0.0235</PDBx:U13>
         <PDBx:U22>0.4413</PDBx:U22>
         <PDBx:U23>-0.0506</PDBx:U23>
         <PDBx:U33>0.2642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="180">
         <PDBx:U11>0.3123</PDBx:U11>
         <PDBx:U12>-0.0414</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>0.3493</PDBx:U22>
         <PDBx:U23>-0.0485</PDBx:U23>
         <PDBx:U33>0.1692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="181">
         <PDBx:U11>0.2436</PDBx:U11>
         <PDBx:U12>-0.0372</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.2922</PDBx:U22>
         <PDBx:U23>-0.0594</PDBx:U23>
         <PDBx:U33>0.1143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="182">
         <PDBx:U11>0.0574</PDBx:U11>
         <PDBx:U12>-0.0195</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.0746</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="183">
         <PDBx:U11>0.0591</PDBx:U11>
         <PDBx:U12>-0.0204</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.0787</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="184">
         <PDBx:U11>0.1068</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.1243</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.0516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="185">
         <PDBx:U11>0.0655</PDBx:U11>
         <PDBx:U12>-0.0288</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.0785</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="186">
         <PDBx:U11>0.0620</PDBx:U11>
         <PDBx:U12>-0.0286</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.0838</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.0398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="187">
         <PDBx:U11>0.0754</PDBx:U11>
         <PDBx:U12>-0.0342</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.0951</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.0401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="188">
         <PDBx:U11>0.1451</PDBx:U11>
         <PDBx:U12>-0.0311</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.1611</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.0514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="189">
         <PDBx:U11>0.1177</PDBx:U11>
         <PDBx:U12>-0.0282</PDBx:U12>
         <PDBx:U13>0.0098</PDBx:U13>
         <PDBx:U22>0.1370</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.0416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="190">
         <PDBx:U11>0.1287</PDBx:U11>
         <PDBx:U12>-0.0397</PDBx:U12>
         <PDBx:U13>0.0141</PDBx:U13>
         <PDBx:U22>0.1560</PDBx:U22>
         <PDBx:U23>-0.0210</PDBx:U23>
         <PDBx:U33>0.0506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="191">
         <PDBx:U11>0.3984</PDBx:U11>
         <PDBx:U12>-0.0463</PDBx:U12>
         <PDBx:U13>0.0237</PDBx:U13>
         <PDBx:U22>0.4218</PDBx:U22>
         <PDBx:U23>-0.0312</PDBx:U23>
         <PDBx:U33>0.2378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="192">
         <PDBx:U11>0.5556</PDBx:U11>
         <PDBx:U12>-0.0533</PDBx:U12>
         <PDBx:U13>0.0276</PDBx:U13>
         <PDBx:U22>0.5866</PDBx:U22>
         <PDBx:U23>-0.0389</PDBx:U23>
         <PDBx:U33>0.3964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="193">
         <PDBx:U11>0.7273</PDBx:U11>
         <PDBx:U12>-0.0577</PDBx:U12>
         <PDBx:U13>0.0298</PDBx:U13>
         <PDBx:U22>0.7594</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.5657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="194">
         <PDBx:U11>0.8605</PDBx:U11>
         <PDBx:U12>-0.0623</PDBx:U12>
         <PDBx:U13>0.0300</PDBx:U13>
         <PDBx:U22>0.8830</PDBx:U22>
         <PDBx:U23>-0.0361</PDBx:U23>
         <PDBx:U33>0.6862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="195">
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         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.1191</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.0455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="196">
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         <PDBx:U12>-0.0302</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.1230</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.0440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="197">
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         <PDBx:U12>-0.0352</PDBx:U12>
         <PDBx:U13>0.0125</PDBx:U13>
         <PDBx:U22>0.1858</PDBx:U22>
         <PDBx:U23>-0.0088</PDBx:U23>
         <PDBx:U33>0.0457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="198">
         <PDBx:U11>0.1582</PDBx:U11>
         <PDBx:U12>-0.0375</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1577</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.0398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="199">
         <PDBx:U11>0.1235</PDBx:U11>
         <PDBx:U12>-0.0253</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.1253</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.0488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="200">
         <PDBx:U11>0.1336</PDBx:U11>
         <PDBx:U12>-0.0234</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1339</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="201">
         <PDBx:U11>0.1686</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1720</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.0551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="202">
         <PDBx:U11>0.1343</PDBx:U11>
         <PDBx:U12>-0.0217</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.1300</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="203">
         <PDBx:U11>0.1699</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.1710</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="204">
         <PDBx:U11>0.1882</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1852</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.0591</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="205">
         <PDBx:U11>0.1449</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1361</PDBx:U22>
         <PDBx:U23>0.0011</PDBx:U23>
         <PDBx:U33>0.0540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="206">
         <PDBx:U11>0.1655</PDBx:U11>
         <PDBx:U12>-0.0185</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.1599</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.0558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="207">
         <PDBx:U11>0.1572</PDBx:U11>
         <PDBx:U12>-0.0192</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.1456</PDBx:U22>
         <PDBx:U23>0.0032</PDBx:U23>
         <PDBx:U33>0.0564</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="208">
         <PDBx:U11>0.1575</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1479</PDBx:U22>
         <PDBx:U23>0.0033</PDBx:U23>
         <PDBx:U33>0.0580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="209">
         <PDBx:U11>0.1523</PDBx:U11>
         <PDBx:U12>-0.0374</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.1604</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
         <PDBx:U33>0.0403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="210">
         <PDBx:U11>0.1730</PDBx:U11>
         <PDBx:U12>-0.0429</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.1793</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.0428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="211">
         <PDBx:U11>0.2540</PDBx:U11>
         <PDBx:U12>-0.0489</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.2586</PDBx:U22>
         <PDBx:U23>-0.0117</PDBx:U23>
         <PDBx:U33>0.0704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="212">
         <PDBx:U11>0.2658</PDBx:U11>
         <PDBx:U12>-0.0518</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.2636</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.0731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="213">
         <PDBx:U11>0.2150</PDBx:U11>
         <PDBx:U12>-0.0404</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.2154</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.0532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="214">
         <PDBx:U11>0.3751</PDBx:U11>
         <PDBx:U12>-0.0353</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.3772</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="215">
         <PDBx:U11>0.5779</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.5746</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.3983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="216">
         <PDBx:U11>0.7912</PDBx:U11>
         <PDBx:U12>-0.0350</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.7836</PDBx:U22>
         <PDBx:U23>0.0042</PDBx:U23>
         <PDBx:U33>0.6039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="217">
         <PDBx:U11>0.9411</PDBx:U11>
         <PDBx:U12>-0.0323</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.9297</PDBx:U22>
         <PDBx:U23>0.0076</PDBx:U23>
         <PDBx:U33>0.7516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="218">
         <PDBx:U11>0.6213</PDBx:U11>
         <PDBx:U12>-0.0270</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.6103</PDBx:U22>
         <PDBx:U23>0.0084</PDBx:U23>
         <PDBx:U33>0.4366</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="219">
         <PDBx:U11>0.8224</PDBx:U11>
         <PDBx:U12>-0.0351</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.8066</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.6256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="220">
         <PDBx:U11>0.1971</PDBx:U11>
         <PDBx:U12>-0.0507</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.2071</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.0513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="221">
         <PDBx:U11>0.1869</PDBx:U11>
         <PDBx:U12>-0.0574</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.1965</PDBx:U22>
         <PDBx:U23>-0.0165</PDBx:U23>
         <PDBx:U33>0.0503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="222">
         <PDBx:U11>0.2031</PDBx:U11>
         <PDBx:U12>-0.0561</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.2064</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.0501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="223">
         <PDBx:U11>0.2198</PDBx:U11>
         <PDBx:U12>-0.0617</PDBx:U12>
         <PDBx:U13>0.0221</PDBx:U13>
         <PDBx:U22>0.2222</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.0466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="224">
         <PDBx:U11>0.1536</PDBx:U11>
         <PDBx:U12>-0.0493</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1528</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
         <PDBx:U33>0.0406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="225">
         <PDBx:U11>0.1437</PDBx:U11>
         <PDBx:U12>-0.0476</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.1370</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.0446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="226">
         <PDBx:U11>0.1909</PDBx:U11>
         <PDBx:U12>-0.0424</PDBx:U12>
         <PDBx:U13>0.0144</PDBx:U13>
         <PDBx:U22>0.1886</PDBx:U22>
         <PDBx:U23>-0.0100</PDBx:U23>
         <PDBx:U33>0.0461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="227">
         <PDBx:U11>0.1587</PDBx:U11>
         <PDBx:U12>-0.0379</PDBx:U12>
         <PDBx:U13>0.0116</PDBx:U13>
         <PDBx:U22>0.1607</PDBx:U22>
         <PDBx:U23>-0.0095</PDBx:U23>
         <PDBx:U33>0.0467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="228">
         <PDBx:U11>0.1704</PDBx:U11>
         <PDBx:U12>-0.0436</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.1563</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="229">
         <PDBx:U11>0.3984</PDBx:U11>
         <PDBx:U12>-0.0485</PDBx:U12>
         <PDBx:U13>0.0126</PDBx:U13>
         <PDBx:U22>0.3770</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.1938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="230">
         <PDBx:U11>0.6290</PDBx:U11>
         <PDBx:U12>-0.0440</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.6000</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.4213</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="231">
         <PDBx:U11>0.4823</PDBx:U11>
         <PDBx:U12>-0.0418</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.4533</PDBx:U22>
         <PDBx:U23>0.0079</PDBx:U23>
         <PDBx:U33>0.2753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="232">
         <PDBx:U11>0.6184</PDBx:U11>
         <PDBx:U12>-0.0426</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.5844</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.4086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="233">
         <PDBx:U11>0.1493</PDBx:U11>
         <PDBx:U12>-0.0431</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.1440</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="234">
         <PDBx:U11>0.1485</PDBx:U11>
         <PDBx:U12>-0.0382</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.1466</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="235">
         <PDBx:U11>0.1765</PDBx:U11>
         <PDBx:U12>-0.0316</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1704</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="236">
         <PDBx:U11>0.1675</PDBx:U11>
         <PDBx:U12>-0.0314</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.1549</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="237">
         <PDBx:U11>0.1775</PDBx:U11>
         <PDBx:U12>-0.0410</PDBx:U12>
         <PDBx:U13>0.0146</PDBx:U13>
         <PDBx:U22>0.1756</PDBx:U22>
         <PDBx:U23>-0.0124</PDBx:U23>
         <PDBx:U33>0.0454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="238">
         <PDBx:U11>0.2723</PDBx:U11>
         <PDBx:U12>-0.0474</PDBx:U12>
         <PDBx:U13>0.0223</PDBx:U13>
         <PDBx:U22>0.2764</PDBx:U22>
         <PDBx:U23>-0.0218</PDBx:U23>
         <PDBx:U33>0.0945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="239">
         <PDBx:U11>0.5894</PDBx:U11>
         <PDBx:U12>-0.0452</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.6033</PDBx:U22>
         <PDBx:U23>-0.0280</PDBx:U23>
         <PDBx:U33>0.4220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="240">
         <PDBx:U11>0.6482</PDBx:U11>
         <PDBx:U12>-0.0410</PDBx:U12>
         <PDBx:U13>0.0223</PDBx:U13>
         <PDBx:U22>0.6663</PDBx:U22>
         <PDBx:U23>-0.0310</PDBx:U23>
         <PDBx:U33>0.4881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="241">
         <PDBx:U11>0.6401</PDBx:U11>
         <PDBx:U12>-0.0474</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.6570</PDBx:U22>
         <PDBx:U23>-0.0298</PDBx:U23>
         <PDBx:U33>0.4734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="242">
         <PDBx:U11>0.1155</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.1130</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="243">
         <PDBx:U11>0.0929</PDBx:U11>
         <PDBx:U12>-0.0213</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.0874</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="244">
         <PDBx:U11>0.1383</PDBx:U11>
         <PDBx:U12>-0.0179</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1353</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="245">
         <PDBx:U11>0.1014</PDBx:U11>
         <PDBx:U12>-0.0188</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1038</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="246">
         <PDBx:U11>0.1266</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.1216</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="247">
         <PDBx:U11>0.1266</PDBx:U11>
         <PDBx:U12>-0.0216</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1185</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="248">
         <PDBx:U11>0.1074</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1080</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="249">
         <PDBx:U11>0.1034</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.0970</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>230</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="250">
         <PDBx:U11>0.1067</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1020</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>230</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="251">
         <PDBx:U11>0.1692</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.1636</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.0538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>230</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="252">
         <PDBx:U11>0.1956</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.1872</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>230</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="253">
         <PDBx:U11>0.1150</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1072</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>230</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="254">
         <PDBx:U11>0.0991</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.0957</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="255">
         <PDBx:U11>0.0941</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.0882</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="256">
         <PDBx:U11>0.1442</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.1360</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.0500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="257">
         <PDBx:U11>0.1382</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1326</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.0474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="258">
         <PDBx:U11>0.1431</PDBx:U11>
         <PDBx:U12>-0.0026</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1400</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.0554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="259">
         <PDBx:U11>0.1356</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1286</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.0557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="260">
         <PDBx:U11>0.1330</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.1323</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="261">
         <PDBx:U11>0.0719</PDBx:U11>
         <PDBx:U12>0.0013</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.0592</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="262">
         <PDBx:U11>0.0662</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.0503</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="263">
         <PDBx:U11>0.1288</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1092</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="264">
         <PDBx:U11>0.1350</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.1130</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.0413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="265">
         <PDBx:U11>0.0979</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.0792</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="266">
         <PDBx:U11>0.3151</PDBx:U11>
         <PDBx:U12>0.0044</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.2936</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.1556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="267">
         <PDBx:U11>0.4085</PDBx:U11>
         <PDBx:U12>0.0034</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.3856</PDBx:U22>
         <PDBx:U23>0.0015</PDBx:U23>
         <PDBx:U33>0.2465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="268">
         <PDBx:U11>0.5463</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.5257</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.3860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="269">
         <PDBx:U11>0.5919</PDBx:U11>
         <PDBx:U12>0.0025</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.5698</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.4296</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="270">
         <PDBx:U11>0.0672</PDBx:U11>
         <PDBx:U12>0.0078</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.0471</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="271">
         <PDBx:U11>0.0656</PDBx:U11>
         <PDBx:U12>0.0095</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.0413</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="272">
         <PDBx:U11>0.1443</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.1120</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="273">
         <PDBx:U11>0.1492</PDBx:U11>
         <PDBx:U12>0.0123</PDBx:U12>
         <PDBx:U13>-0.0099</PDBx:U13>
         <PDBx:U22>0.1173</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.0532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="274">
         <PDBx:U11>0.1130</PDBx:U11>
         <PDBx:U12>0.0117</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.0925</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.0480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="275">
         <PDBx:U11>0.1260</PDBx:U11>
         <PDBx:U12>0.0089</PDBx:U12>
         <PDBx:U13>-0.0051</PDBx:U13>
         <PDBx:U22>0.1113</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.0542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="276">
         <PDBx:U11>0.1088</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>0.0821</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.0476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="277">
         <PDBx:U11>0.2051</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>0.1972</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.0856</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="278">
         <PDBx:U11>0.1286</PDBx:U11>
         <PDBx:U12>0.0104</PDBx:U12>
         <PDBx:U13>-0.0085</PDBx:U13>
         <PDBx:U22>0.0892</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="279">
         <PDBx:U11>0.1354</PDBx:U11>
         <PDBx:U12>0.0107</PDBx:U12>
         <PDBx:U13>-0.0095</PDBx:U13>
         <PDBx:U22>0.0870</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.0499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="280">
         <PDBx:U11>0.1252</PDBx:U11>
         <PDBx:U12>0.0125</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>0.0694</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.0498</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="281">
         <PDBx:U11>0.1452</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>-0.0121</PDBx:U13>
         <PDBx:U22>0.0915</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="282">
         <PDBx:U11>0.1624</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.1114</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.0546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="283">
         <PDBx:U11>0.1752</PDBx:U11>
         <PDBx:U12>0.0054</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.1302</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.0647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="284">
         <PDBx:U11>0.1966</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1582</PDBx:U22>
         <PDBx:U23>0.0015</PDBx:U23>
         <PDBx:U33>0.0762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="285">
         <PDBx:U11>0.1839</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.1373</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.0669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="286">
         <PDBx:U11>0.2093</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.1751</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.0820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="287">
         <PDBx:U11>0.2005</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0066</PDBx:U13>
         <PDBx:U22>0.1591</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.0748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="288">
         <PDBx:U11>0.1717</PDBx:U11>
         <PDBx:U12>0.0029</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1361</PDBx:U22>
         <PDBx:U23>0.0017</PDBx:U23>
         <PDBx:U33>0.0762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="289">
         <PDBx:U11>0.1070</PDBx:U11>
         <PDBx:U12>0.0141</PDBx:U12>
         <PDBx:U13>-0.0106</PDBx:U13>
         <PDBx:U22>0.0419</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>235</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="290">
         <PDBx:U11>0.1192</PDBx:U11>
         <PDBx:U12>0.0157</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.0444</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>235</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="291">
         <PDBx:U11>0.1784</PDBx:U11>
         <PDBx:U12>0.0112</PDBx:U12>
         <PDBx:U13>-0.0204</PDBx:U13>
         <PDBx:U22>0.0966</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>235</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="292">
         <PDBx:U11>0.1697</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0171</PDBx:U13>
         <PDBx:U22>0.0898</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>235</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="293">
         <PDBx:U11>0.1860</PDBx:U11>
         <PDBx:U12>0.0192</PDBx:U12>
         <PDBx:U13>-0.0274</PDBx:U13>
         <PDBx:U22>0.1054</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0573</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>235</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="294">
         <PDBx:U11>0.2916</PDBx:U11>
         <PDBx:U12>0.0168</PDBx:U12>
         <PDBx:U13>-0.0401</PDBx:U13>
         <PDBx:U22>0.2075</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.0959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>235</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="295">
         <PDBx:U11>0.1747</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>-0.0216</PDBx:U13>
         <PDBx:U22>0.0832</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>236</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="296">
         <PDBx:U11>0.1900</PDBx:U11>
         <PDBx:U12>0.0068</PDBx:U12>
         <PDBx:U13>-0.0221</PDBx:U13>
         <PDBx:U22>0.0900</PDBx:U22>
         <PDBx:U23>0.0011</PDBx:U23>
         <PDBx:U33>0.0519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>236</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="297">
         <PDBx:U11>0.2535</PDBx:U11>
         <PDBx:U12>0.0034</PDBx:U12>
         <PDBx:U13>-0.0284</PDBx:U13>
         <PDBx:U22>0.1477</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>0.0681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>236</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="298">
         <PDBx:U11>0.2943</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>-0.0298</PDBx:U13>
         <PDBx:U22>0.1887</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.0666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>236</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="299">
         <PDBx:U11>0.2222</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0316</PDBx:U13>
         <PDBx:U22>0.1116</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>236</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="300">
         <PDBx:U11>0.2435</PDBx:U11>
         <PDBx:U12>0.0129</PDBx:U12>
         <PDBx:U13>-0.0414</PDBx:U13>
         <PDBx:U22>0.1268</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.0497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>236</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="301">
         <PDBx:U11>0.1851</PDBx:U11>
         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>-0.0223</PDBx:U13>
         <PDBx:U22>0.0733</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="302">
         <PDBx:U11>0.1991</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>-0.0248</PDBx:U13>
         <PDBx:U22>0.0813</PDBx:U22>
         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.0517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="303">
         <PDBx:U11>0.2207</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>-0.0245</PDBx:U13>
         <PDBx:U22>0.1141</PDBx:U22>
         <PDBx:U23>0.0052</PDBx:U23>
         <PDBx:U33>0.0542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="304">
         <PDBx:U11>0.1903</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>-0.0211</PDBx:U13>
         <PDBx:U22>0.0794</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.0418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="305">
         <PDBx:U11>0.2152</PDBx:U11>
         <PDBx:U12>0.0053</PDBx:U12>
         <PDBx:U13>-0.0337</PDBx:U13>
         <PDBx:U22>0.0882</PDBx:U22>
         <PDBx:U23>0.0033</PDBx:U23>
         <PDBx:U33>0.0453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="306">
         <PDBx:U11>0.1680</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>-0.0264</PDBx:U13>
         <PDBx:U22>0.0487</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.0435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="307">
         <PDBx:U11>0.2943</PDBx:U11>
         <PDBx:U12>0.0144</PDBx:U12>
         <PDBx:U13>-0.0529</PDBx:U13>
         <PDBx:U22>0.1680</PDBx:U22>
         <PDBx:U23>0.0047</PDBx:U23>
         <PDBx:U33>0.0779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="308">
         <PDBx:U11>0.2090</PDBx:U11>
         <PDBx:U12>0.0196</PDBx:U12>
         <PDBx:U13>-0.0417</PDBx:U13>
         <PDBx:U22>0.0871</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="309">
         <PDBx:U11>0.2744</PDBx:U11>
         <PDBx:U12>0.0247</PDBx:U12>
         <PDBx:U13>-0.0659</PDBx:U13>
         <PDBx:U22>0.1500</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="310">
         <PDBx:U11>0.2680</PDBx:U11>
         <PDBx:U12>0.0229</PDBx:U12>
         <PDBx:U13>-0.0652</PDBx:U13>
         <PDBx:U22>0.1259</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.0579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="311">
         <PDBx:U11>0.2057</PDBx:U11>
         <PDBx:U12>0.0292</PDBx:U12>
         <PDBx:U13>-0.0498</PDBx:U13>
         <PDBx:U22>0.0850</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.0544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="312">
         <PDBx:U11>0.1371</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>-0.0131</PDBx:U13>
         <PDBx:U22>0.0428</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>238</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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      <PDBx:atom_site_anisotrop id="329">
         <PDBx:U11>0.6873</PDBx:U11>
         <PDBx:U12>-0.0214</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.6049</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.4582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="330">
         <PDBx:U11>0.1335</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.0544</PDBx:U22>
         <PDBx:U23>0.0017</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="331">
         <PDBx:U11>0.1321</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.0583</PDBx:U22>
         <PDBx:U23>0.0017</PDBx:U23>
         <PDBx:U33>0.0383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="332">
         <PDBx:U11>0.2144</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.1502</PDBx:U22>
         <PDBx:U23>0.0061</PDBx:U23>
         <PDBx:U33>0.0510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="333">
         <PDBx:U11>0.2245</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1677</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.0511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="334">
         <PDBx:U11>0.1532</PDBx:U11>
         <PDBx:U12>-0.0226</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.0712</PDBx:U22>
         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="335">
         <PDBx:U11>0.3060</PDBx:U11>
         <PDBx:U12>-0.0272</PDBx:U12>
         <PDBx:U13>-0.0076</PDBx:U13>
         <PDBx:U22>0.2126</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.0697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="336">
         <PDBx:U11>0.4560</PDBx:U11>
         <PDBx:U12>-0.0330</PDBx:U12>
         <PDBx:U13>-0.0076</PDBx:U13>
         <PDBx:U22>0.3557</PDBx:U22>
         <PDBx:U23>0.0123</PDBx:U23>
         <PDBx:U33>0.1978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="337">
         <PDBx:U11>0.7055</PDBx:U11>
         <PDBx:U12>-0.0356</PDBx:U12>
         <PDBx:U13>-0.0121</PDBx:U13>
         <PDBx:U22>0.5898</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.4330</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="338">
         <PDBx:U11>1.0263</PDBx:U11>
         <PDBx:U12>-0.0412</PDBx:U12>
         <PDBx:U13>-0.0130</PDBx:U13>
         <PDBx:U22>0.9016</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.7411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="339">
         <PDBx:U11>0.8981</PDBx:U11>
         <PDBx:U12>-0.0448</PDBx:U12>
         <PDBx:U13>-0.0092</PDBx:U13>
         <PDBx:U22>0.7793</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.6135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="340">
         <PDBx:U11>0.9574</PDBx:U11>
         <PDBx:U12>-0.0433</PDBx:U12>
         <PDBx:U13>-0.0179</PDBx:U13>
         <PDBx:U22>0.8171</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.6582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="341">
         <PDBx:U11>0.1356</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.0716</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.0419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>241</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="342">
         <PDBx:U11>0.1155</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.0598</PDBx:U22>
         <PDBx:U23>0.0011</PDBx:U23>
         <PDBx:U33>0.0436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>241</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="343">
         <PDBx:U11>0.1718</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.1226</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.0542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>241</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="344">
         <PDBx:U11>0.1669</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.1242</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.0494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>241</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="345">
         <PDBx:U11>0.1023</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.0449</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>242</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="362">
         <PDBx:U11>0.0837</PDBx:U11>
         <PDBx:U12>-0.0122</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.0413</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="363">
         <PDBx:U11>0.0927</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.0555</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="364">
         <PDBx:U11>0.0732</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.0422</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="365">
         <PDBx:U11>0.1163</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.0670</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.0443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="366">
         <PDBx:U11>0.1551</PDBx:U11>
         <PDBx:U12>-0.0198</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1104</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="367">
         <PDBx:U11>0.2241</PDBx:U11>
         <PDBx:U12>-0.0196</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1818</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0633</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="368">
         <PDBx:U11>0.2207</PDBx:U11>
         <PDBx:U12>-0.0231</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.1790</PDBx:U22>
         <PDBx:U23>0.0011</PDBx:U23>
         <PDBx:U33>0.0711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="369">
         <PDBx:U11>0.2378</PDBx:U11>
         <PDBx:U12>-0.0222</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.2008</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.0693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="370">
         <PDBx:U11>0.2730</PDBx:U11>
         <PDBx:U12>-0.0258</PDBx:U12>
         <PDBx:U13>0.0128</PDBx:U13>
         <PDBx:U22>0.2372</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="371">
         <PDBx:U11>0.2296</PDBx:U11>
         <PDBx:U12>-0.0253</PDBx:U12>
         <PDBx:U13>0.0104</PDBx:U13>
         <PDBx:U22>0.1958</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="372">
         <PDBx:U11>0.0822</PDBx:U11>
         <PDBx:U12>-0.0136</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.0428</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="373">
         <PDBx:U11>0.0845</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.0504</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="374">
         <PDBx:U11>0.1173</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.0885</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="375">
         <PDBx:U11>0.1446</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.1210</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="376">
         <PDBx:U11>0.0832</PDBx:U11>
         <PDBx:U12>-0.0158</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.0455</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="377">
         <PDBx:U11>0.0813</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.0491</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="378">
         <PDBx:U11>0.1314</PDBx:U11>
         <PDBx:U12>-0.0189</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1043</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="379">
         <PDBx:U11>0.1089</PDBx:U11>
         <PDBx:U12>-0.0199</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0862</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="380">
         <PDBx:U11>0.2834</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>0.0148</PDBx:U13>
         <PDBx:U22>0.2676</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.1066</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="381">
         <PDBx:U11>0.1112</PDBx:U11>
         <PDBx:U12>-0.0225</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.0973</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="382">
         <PDBx:U11>0.1930</PDBx:U11>
         <PDBx:U12>-0.0215</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.1815</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.0626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="383">
         <PDBx:U11>0.0701</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.0415</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="384">
         <PDBx:U11>0.0622</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.0388</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="385">
         <PDBx:U11>0.0675</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.0443</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="386">
         <PDBx:U11>0.0558</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.0385</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="387">
         <PDBx:U11>0.0650</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0407</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="388">
         <PDBx:U11>0.2259</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.2012</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>0.0734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="389">
         <PDBx:U11>0.5219</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.4969</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.3551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="390">
         <PDBx:U11>0.4030</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.3753</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>0.2338</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="391">
         <PDBx:U11>0.4348</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.4121</PDBx:U22>
         <PDBx:U23>0.0052</PDBx:U23>
         <PDBx:U33>0.2707</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="392">
         <PDBx:U11>0.0610</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.0389</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>246</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="393">
         <PDBx:U11>0.0675</PDBx:U11>
         <PDBx:U12>-0.0051</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.0459</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>246</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="394">
         <PDBx:U11>0.1100</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.0921</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.0442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="411">
         <PDBx:U11>0.0714</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.0570</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.0439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="412">
         <PDBx:U11>0.1242</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1118</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="413">
         <PDBx:U11>0.1484</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.1395</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="414">
         <PDBx:U11>0.0739</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.0607</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.0482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="415">
         <PDBx:U11>0.0930</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.0796</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.0486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="416">
         <PDBx:U11>0.1346</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1236</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.0483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="417">
         <PDBx:U11>0.1253</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1140</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.0451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="418">
         <PDBx:U11>0.1184</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.1026</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.0521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="419">
         <PDBx:U11>0.1677</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1501</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.0656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="420">
         <PDBx:U11>0.2031</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1846</PDBx:U22>
         <PDBx:U23>0.0052</PDBx:U23>
         <PDBx:U33>0.0737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="421">
         <PDBx:U11>0.1963</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1775</PDBx:U22>
         <PDBx:U23>0.0048</PDBx:U23>
         <PDBx:U33>0.0674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="422">
         <PDBx:U11>0.2679</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.2478</PDBx:U22>
         <PDBx:U23>0.0068</PDBx:U23>
         <PDBx:U33>0.1086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="423">
         <PDBx:U11>0.2016</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.1818</PDBx:U22>
         <PDBx:U23>0.0050</PDBx:U23>
         <PDBx:U33>0.0681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="424">
         <PDBx:U11>0.2936</PDBx:U11>
         <PDBx:U12>0.0004</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.2735</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.1335</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="425">
         <PDBx:U11>0.3627</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.3419</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.2024</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="426">
         <PDBx:U11>0.0812</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.0725</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.0502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="427">
         <PDBx:U11>0.0783</PDBx:U11>
         <PDBx:U12>-0.0011</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.0730</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="428">
         <PDBx:U11>0.1151</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.1144</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="429">
         <PDBx:U11>0.1008</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1040</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="430">
         <PDBx:U11>0.0896</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.0843</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0537</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="431">
         <PDBx:U11>0.0515</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.0429</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="432">
         <PDBx:U11>0.2862</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.2771</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.1249</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="433">
         <PDBx:U11>0.1163</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1098</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="434">
         <PDBx:U11>0.2024</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1892</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="435">
         <PDBx:U11>0.0515</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.0509</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="436">
         <PDBx:U11>0.0521</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0565</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="437">
         <PDBx:U11>0.0543</PDBx:U11>
         <PDBx:U12>0.0044</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.0597</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="438">
         <PDBx:U11>0.0743</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.0746</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="439">
         <PDBx:U11>0.0866</PDBx:U11>
         <PDBx:U12>0.0013</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.0899</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.0464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="440">
         <PDBx:U11>0.0528</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.0548</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="441">
         <PDBx:U11>0.0970</PDBx:U11>
         <PDBx:U12>0.0027</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1058</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="442">
         <PDBx:U11>0.0537</PDBx:U11>
         <PDBx:U12>0.0049</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.0656</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="443">
         <PDBx:U11>0.0569</PDBx:U11>
         <PDBx:U12>0.0087</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.0703</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="444">
         <PDBx:U11>0.0726</PDBx:U11>
         <PDBx:U12>0.0124</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.0814</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="445">
         <PDBx:U11>0.0586</PDBx:U11>
         <PDBx:U12>0.0126</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.0684</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="446">
         <PDBx:U11>0.1133</PDBx:U11>
         <PDBx:U12>0.0086</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.1352</PDBx:U22>
         <PDBx:U23>-0.0156</PDBx:U23>
         <PDBx:U33>0.0431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="447">
         <PDBx:U11>0.1074</PDBx:U11>
         <PDBx:U12>0.0135</PDBx:U12>
         <PDBx:U13>-0.0068</PDBx:U13>
         <PDBx:U22>0.1305</PDBx:U22>
         <PDBx:U23>-0.0172</PDBx:U23>
         <PDBx:U33>0.0420</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="448">
         <PDBx:U11>0.1189</PDBx:U11>
         <PDBx:U12>0.0048</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1437</PDBx:U22>
         <PDBx:U23>-0.0169</PDBx:U23>
         <PDBx:U33>0.0414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="449">
         <PDBx:U11>0.0711</PDBx:U11>
         <PDBx:U12>0.0150</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.0743</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="450">
         <PDBx:U11>0.1017</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>-0.0080</PDBx:U13>
         <PDBx:U22>0.0980</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.0495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="451">
         <PDBx:U11>0.1337</PDBx:U11>
         <PDBx:U12>0.0163</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.1252</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.0475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="452">
         <PDBx:U11>0.1514</PDBx:U11>
         <PDBx:U12>0.0185</PDBx:U12>
         <PDBx:U13>-0.0143</PDBx:U13>
         <PDBx:U22>0.1389</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.0549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="453">
         <PDBx:U11>0.1412</PDBx:U11>
         <PDBx:U12>0.0215</PDBx:U12>
         <PDBx:U13>-0.0162</PDBx:U13>
         <PDBx:U22>0.1419</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.0533</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="454">
         <PDBx:U11>0.2219</PDBx:U11>
         <PDBx:U12>0.0235</PDBx:U12>
         <PDBx:U13>-0.0253</PDBx:U13>
         <PDBx:U22>0.2248</PDBx:U22>
         <PDBx:U23>-0.0202</PDBx:U23>
         <PDBx:U33>0.1044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="455">
         <PDBx:U11>0.3281</PDBx:U11>
         <PDBx:U12>0.0293</PDBx:U12>
         <PDBx:U13>-0.0321</PDBx:U13>
         <PDBx:U22>0.3305</PDBx:U22>
         <PDBx:U23>-0.0253</PDBx:U23>
         <PDBx:U33>0.2182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="456">
         <PDBx:U11>0.3069</PDBx:U11>
         <PDBx:U12>0.0310</PDBx:U12>
         <PDBx:U13>-0.0381</PDBx:U13>
         <PDBx:U22>0.2948</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.1875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="457">
         <PDBx:U11>0.1042</PDBx:U11>
         <PDBx:U12>0.0129</PDBx:U12>
         <PDBx:U13>-0.0055</PDBx:U13>
         <PDBx:U22>0.0954</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.0438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="458">
         <PDBx:U11>0.0900</PDBx:U11>
         <PDBx:U12>0.0115</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.0771</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="459">
         <PDBx:U11>0.1213</PDBx:U11>
         <PDBx:U12>0.0114</PDBx:U12>
         <PDBx:U13>-0.0065</PDBx:U13>
         <PDBx:U22>0.1006</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="460">
         <PDBx:U11>0.1016</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.0770</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="461">
         <PDBx:U11>0.0813</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.0704</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="462">
         <PDBx:U11>0.1249</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1108</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="463">
         <PDBx:U11>0.1383</PDBx:U11>
         <PDBx:U12>0.0075</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.1258</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="464">
         <PDBx:U11>0.1351</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1216</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="465">
         <PDBx:U11>0.0776</PDBx:U11>
         <PDBx:U12>0.0104</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.0542</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="466">
         <PDBx:U11>0.0936</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.0632</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="467">
         <PDBx:U11>0.1248</PDBx:U11>
         <PDBx:U12>0.0107</PDBx:U12>
         <PDBx:U13>-0.0101</PDBx:U13>
         <PDBx:U22>0.0880</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.0398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="468">
         <PDBx:U11>0.1054</PDBx:U11>
         <PDBx:U12>0.0138</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.0679</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="469">
         <PDBx:U11>0.1171</PDBx:U11>
         <PDBx:U12>0.0077</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.0854</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.0429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="470">
         <PDBx:U11>0.1444</PDBx:U11>
         <PDBx:U12>0.0055</PDBx:U12>
         <PDBx:U13>-0.0076</PDBx:U13>
         <PDBx:U22>0.1176</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.0470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="471">
         <PDBx:U11>0.2328</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>-0.0127</PDBx:U13>
         <PDBx:U22>0.2048</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.0838</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="472">
         <PDBx:U11>0.2446</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>-0.0146</PDBx:U13>
         <PDBx:U22>0.2104</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.0731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="473">
         <PDBx:U11>0.3123</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.2790</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.1384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="474">
         <PDBx:U11>0.1398</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>-0.0047</PDBx:U13>
         <PDBx:U22>0.1123</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="475">
         <PDBx:U11>0.2544</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.2161</PDBx:U22>
         <PDBx:U23>0.0156</PDBx:U23>
         <PDBx:U33>0.0741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="476">
         <PDBx:U11>0.1024</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>-0.0068</PDBx:U13>
         <PDBx:U22>0.0608</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0105</PDBx:U13>
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         <PDBx:U23>0.0017</PDBx:U23>
         <PDBx:U33>0.0451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0114</PDBx:U13>
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         <PDBx:U23>0.0044</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0069</PDBx:U13>
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         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0010</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0187</PDBx:U13>
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         <PDBx:U23>0.0033</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0212</PDBx:U13>
         <PDBx:U22>0.1625</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0027</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="484">
         <PDBx:U11>0.2224</PDBx:U11>
         <PDBx:U12>0.0136</PDBx:U12>
         <PDBx:U13>-0.0247</PDBx:U13>
         <PDBx:U22>0.1589</PDBx:U22>
         <PDBx:U23>0.0064</PDBx:U23>
         <PDBx:U33>0.0697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="485">
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         <PDBx:U12>0.0179</PDBx:U12>
         <PDBx:U13>-0.0290</PDBx:U13>
         <PDBx:U22>0.1576</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.0699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="486">
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         <PDBx:U12>0.0051</PDBx:U12>
         <PDBx:U13>-0.0161</PDBx:U13>
         <PDBx:U22>0.1041</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.0449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="487">
         <PDBx:U11>0.1813</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>-0.0160</PDBx:U13>
         <PDBx:U22>0.1130</PDBx:U22>
         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.0447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>-0.0130</PDBx:U13>
         <PDBx:U22>0.1195</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.0481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.1167</PDBx:U22>
         <PDBx:U23>0.0095</PDBx:U23>
         <PDBx:U33>0.0460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U13>-0.0236</PDBx:U13>
         <PDBx:U22>0.1415</PDBx:U22>
         <PDBx:U23>0.0152</PDBx:U23>
         <PDBx:U33>0.0491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.1506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.7436</PDBx:U11>
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         <PDBx:U23>0.0205</PDBx:U23>
         <PDBx:U33>0.5386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>0.0134</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0041</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U22>0.0382</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0035</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.0659</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0026</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.0509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0001</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0003</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0049</PDBx:U23>
         <PDBx:U33>0.0406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0035</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U33>0.0471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="526">
         <PDBx:U11>0.1829</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1636</PDBx:U22>
         <PDBx:U23>0.0074</PDBx:U23>
         <PDBx:U33>0.0600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="527">
         <PDBx:U11>0.0691</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.0516</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="528">
         <PDBx:U11>0.0775</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.0617</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.0431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="529">
         <PDBx:U11>0.1413</PDBx:U11>
         <PDBx:U12>-0.0015</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1247</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.0517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="530">
         <PDBx:U11>0.1219</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1078</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="531">
         <PDBx:U11>0.1587</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1420</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.0525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="532">
         <PDBx:U11>0.1850</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.1714</PDBx:U22>
         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.0600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="533">
         <PDBx:U11>0.1523</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1368</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.0566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="534">
         <PDBx:U11>0.0547</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.0391</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="535">
         <PDBx:U11>0.0550</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.0400</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="536">
         <PDBx:U11>0.1012</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.0880</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.0411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="537">
         <PDBx:U11>0.0526</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.0404</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="538">
         <PDBx:U11>0.1048</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.0900</PDBx:U22>
         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="539">
         <PDBx:U11>0.1261</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1080</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="540">
         <PDBx:U11>0.1123</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.0995</PDBx:U22>
         <PDBx:U23>0.0029</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="541">
         <PDBx:U11>0.1353</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1180</PDBx:U22>
         <PDBx:U23>0.0030</PDBx:U23>
         <PDBx:U33>0.0522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="542">
         <PDBx:U11>0.0513</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.0395</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="543">
         <PDBx:U11>0.0523</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0404</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="544">
         <PDBx:U11>0.1146</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.1000</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.0447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="545">
         <PDBx:U11>0.1340</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.1189</PDBx:U22>
         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.0472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="546">
         <PDBx:U11>0.0504</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0402</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="547">
         <PDBx:U11>0.0635</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.0476</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="548">
         <PDBx:U11>0.0875</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.0681</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="549">
         <PDBx:U11>0.1527</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1331</PDBx:U22>
         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.0509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="550">
         <PDBx:U11>0.1649</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1477</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.0455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="551">
         <PDBx:U11>0.1057</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0840</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.0443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="552">
         <PDBx:U11>0.1226</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1003</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.0507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="553">
         <PDBx:U11>0.1094</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.0866</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.0503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="554">
         <PDBx:U11>0.1976</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1695</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.0556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="555">
         <PDBx:U11>0.1880</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1576</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.0540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="556">
         <PDBx:U11>0.1282</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1106</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="557">
         <PDBx:U11>0.2064</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1901</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="558">
         <PDBx:U11>0.2203</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.2000</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0035</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0003</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0008</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U33>0.4756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.4401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U22>0.1057</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.0621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0098</PDBx:U13>
         <PDBx:U22>0.1123</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.0604</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="575">
         <PDBx:U11>0.3874</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.3881</PDBx:U22>
         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.2573</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="576">
         <PDBx:U11>0.2680</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.2762</PDBx:U22>
         <PDBx:U23>-0.0294</PDBx:U23>
         <PDBx:U33>0.1407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="577">
         <PDBx:U11>0.1198</PDBx:U11>
         <PDBx:U12>0.0115</PDBx:U12>
         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.0811</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="578">
         <PDBx:U11>0.1288</PDBx:U11>
         <PDBx:U12>0.0154</PDBx:U12>
         <PDBx:U13>-0.0132</PDBx:U13>
         <PDBx:U22>0.0824</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.0471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="579">
         <PDBx:U11>0.1605</PDBx:U11>
         <PDBx:U12>0.0174</PDBx:U12>
         <PDBx:U13>-0.0199</PDBx:U13>
         <PDBx:U22>0.1222</PDBx:U22>
         <PDBx:U23>-0.0191</PDBx:U23>
         <PDBx:U33>0.0470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="580">
         <PDBx:U11>0.1658</PDBx:U11>
         <PDBx:U12>0.0155</PDBx:U12>
         <PDBx:U13>-0.0188</PDBx:U13>
         <PDBx:U22>0.1344</PDBx:U22>
         <PDBx:U23>-0.0236</PDBx:U23>
         <PDBx:U33>0.0470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="581">
         <PDBx:U11>0.1840</PDBx:U11>
         <PDBx:U12>0.0132</PDBx:U12>
         <PDBx:U13>-0.0187</PDBx:U13>
         <PDBx:U22>0.1299</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.0565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="582">
         <PDBx:U11>0.2917</PDBx:U11>
         <PDBx:U12>0.0158</PDBx:U12>
         <PDBx:U13>-0.0294</PDBx:U13>
         <PDBx:U22>0.2254</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.1285</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="583">
         <PDBx:U11>0.2935</PDBx:U11>
         <PDBx:U12>0.0201</PDBx:U12>
         <PDBx:U13>-0.0341</PDBx:U13>
         <PDBx:U22>0.2272</PDBx:U22>
         <PDBx:U23>-0.0217</PDBx:U23>
         <PDBx:U33>0.1359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="584">
         <PDBx:U11>0.3609</PDBx:U11>
         <PDBx:U12>0.0138</PDBx:U12>
         <PDBx:U13>-0.0299</PDBx:U13>
         <PDBx:U22>0.2849</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.1886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="585">
         <PDBx:U11>0.1338</PDBx:U11>
         <PDBx:U12>0.0223</PDBx:U12>
         <PDBx:U13>-0.0198</PDBx:U13>
         <PDBx:U22>0.0957</PDBx:U22>
         <PDBx:U23>-0.0161</PDBx:U23>
         <PDBx:U33>0.0479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="586">
         <PDBx:U11>0.1029</PDBx:U11>
         <PDBx:U12>0.0258</PDBx:U12>
         <PDBx:U13>-0.0178</PDBx:U13>
         <PDBx:U22>0.0766</PDBx:U22>
         <PDBx:U23>-0.0153</PDBx:U23>
         <PDBx:U33>0.0454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="587">
         <PDBx:U11>0.1644</PDBx:U11>
         <PDBx:U12>0.0278</PDBx:U12>
         <PDBx:U13>-0.0293</PDBx:U13>
         <PDBx:U22>0.1315</PDBx:U22>
         <PDBx:U23>-0.0313</PDBx:U23>
         <PDBx:U33>0.0676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="588">
         <PDBx:U11>0.1772</PDBx:U11>
         <PDBx:U12>0.0285</PDBx:U12>
         <PDBx:U13>-0.0342</PDBx:U13>
         <PDBx:U22>0.1506</PDBx:U22>
         <PDBx:U23>-0.0453</PDBx:U23>
         <PDBx:U33>0.0696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="589">
         <PDBx:U11>0.1199</PDBx:U11>
         <PDBx:U12>0.0274</PDBx:U12>
         <PDBx:U13>-0.0217</PDBx:U13>
         <PDBx:U22>0.0977</PDBx:U22>
         <PDBx:U23>-0.0222</PDBx:U23>
         <PDBx:U33>0.0508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="590">
         <PDBx:U11>0.2065</PDBx:U11>
         <PDBx:U12>0.0293</PDBx:U12>
         <PDBx:U13>-0.0382</PDBx:U13>
         <PDBx:U22>0.1705</PDBx:U22>
         <PDBx:U23>-0.0390</PDBx:U23>
         <PDBx:U33>0.0800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>-0.0031</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0026</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0057</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0143</PDBx:U23>
         <PDBx:U33>0.0754</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.0169</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>0.4122</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.2967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="632">
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         <PDBx:U13>-0.0166</PDBx:U13>
         <PDBx:U22>0.2762</PDBx:U22>
         <PDBx:U23>-0.0226</PDBx:U23>
         <PDBx:U33>0.1567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="633">
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         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>0.3866</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.2726</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="634">
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         <PDBx:U12>0.0083</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.0647</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.0451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>-0.0047</PDBx:U13>
         <PDBx:U22>0.0717</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.0792</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.0809</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.0491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0017</PDBx:U23>
         <PDBx:U33>0.0614</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="640">
         <PDBx:U11>0.1667</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>0.0990</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.0592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="641">
         <PDBx:U11>0.2392</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>-0.0112</PDBx:U13>
         <PDBx:U22>0.1783</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.0655</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="642">
         <PDBx:U11>0.0722</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.0439</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="643">
         <PDBx:U11>0.0758</PDBx:U11>
         <PDBx:U12>0.0027</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.0511</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="644">
         <PDBx:U11>0.0990</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.0753</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.0455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="645">
         <PDBx:U11>0.0693</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.0446</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="646">
         <PDBx:U11>0.0677</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.0477</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="647">
         <PDBx:U11>0.0928</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.0748</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="648">
         <PDBx:U11>0.1338</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>-0.0045</PDBx:U13>
         <PDBx:U22>0.1121</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.0481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="649">
         <PDBx:U11>0.0935</PDBx:U11>
         <PDBx:U12>0.0023</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.0822</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="650">
         <PDBx:U11>0.1299</PDBx:U11>
         <PDBx:U12>0.0075</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.1128</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="651">
         <PDBx:U11>0.1450</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1346</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.0520</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="652">
         <PDBx:U11>0.1068</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0999</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="653">
         <PDBx:U11>0.1244</PDBx:U11>
         <PDBx:U12>0.0037</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.1215</PDBx:U22>
         <PDBx:U23>-0.0109</PDBx:U23>
         <PDBx:U33>0.0466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="654">
         <PDBx:U11>0.1286</PDBx:U11>
         <PDBx:U12>-0.0025</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1275</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.0463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="655">
         <PDBx:U11>0.1391</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1405</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.0490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="656">
         <PDBx:U11>0.0837</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.0627</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="657">
         <PDBx:U11>0.0633</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.0437</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="658">
         <PDBx:U11>0.0724</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.0564</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="659">
         <PDBx:U11>0.0511</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.0380</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="660">
         <PDBx:U11>0.0851</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0639</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.0442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="661">
         <PDBx:U11>0.1543</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.1291</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="662">
         <PDBx:U11>0.1690</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1425</PDBx:U22>
         <PDBx:U23>0.0034</PDBx:U23>
         <PDBx:U33>0.0569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="663">
         <PDBx:U11>0.1695</PDBx:U11>
         <PDBx:U12>-0.0015</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1448</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.0543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="664">
         <PDBx:U11>0.0507</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0384</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="665">
         <PDBx:U11>0.0515</PDBx:U11>
         <PDBx:U12>-0.0045</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.0395</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="666">
         <PDBx:U11>0.0784</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.0646</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="667">
         <PDBx:U11>0.0519</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0391</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="668">
         <PDBx:U11>0.1023</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.0920</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="669">
         <PDBx:U11>0.1185</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1104</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="670">
         <PDBx:U11>0.1052</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.0957</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="671">
         <PDBx:U11>0.0532</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.0404</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="672">
         <PDBx:U11>0.0555</PDBx:U11>
         <PDBx:U12>-0.0064</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0404</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="673">
         <PDBx:U11>0.0900</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0727</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="674">
         <PDBx:U11>0.0592</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.0449</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="675">
         <PDBx:U11>0.0912</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.0735</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="676">
         <PDBx:U11>0.1325</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.1157</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="677">
         <PDBx:U11>0.0815</PDBx:U11>
         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.0604</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="678">
         <PDBx:U11>0.1087</PDBx:U11>
         <PDBx:U12>-0.0151</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.0850</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="679">
         <PDBx:U11>0.2005</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.1794</PDBx:U22>
         <PDBx:U23>0.0032</PDBx:U23>
         <PDBx:U33>0.0516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="680">
         <PDBx:U11>0.2147</PDBx:U11>
         <PDBx:U12>-0.0136</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.1951</PDBx:U22>
         <PDBx:U23>0.0030</PDBx:U23>
         <PDBx:U33>0.0563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="681">
         <PDBx:U11>0.1436</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1136</PDBx:U22>
         <PDBx:U23>0.0042</PDBx:U23>
         <PDBx:U33>0.0446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="682">
         <PDBx:U11>0.2849</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2516</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.1024</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="683">
         <PDBx:U11>0.2794</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.2488</PDBx:U22>
         <PDBx:U23>0.0116</PDBx:U23>
         <PDBx:U33>0.0977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="684">
         <PDBx:U11>0.2738</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.2353</PDBx:U22>
         <PDBx:U23>0.0136</PDBx:U23>
         <PDBx:U33>0.0888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="685">
         <PDBx:U11>0.1409</PDBx:U11>
         <PDBx:U12>-0.0209</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1202</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.0469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="686">
         <PDBx:U11>0.1465</PDBx:U11>
         <PDBx:U12>-0.0231</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1292</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="687">
         <PDBx:U11>0.1685</PDBx:U11>
         <PDBx:U12>-0.0266</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.1460</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="688">
         <PDBx:U11>0.1542</PDBx:U11>
         <PDBx:U12>-0.0306</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.1268</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="689">
         <PDBx:U11>0.1762</PDBx:U11>
         <PDBx:U12>-0.0262</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1649</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.0597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="690">
         <PDBx:U11>0.1874</PDBx:U11>
         <PDBx:U12>-0.0288</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.1807</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.0677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="691">
         <PDBx:U11>0.2130</PDBx:U11>
         <PDBx:U12>-0.0248</PDBx:U12>
         <PDBx:U13>0.0122</PDBx:U13>
         <PDBx:U22>0.2104</PDBx:U22>
         <PDBx:U23>-0.0117</PDBx:U23>
         <PDBx:U33>0.0734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="692">
         <PDBx:U11>0.2125</PDBx:U11>
         <PDBx:U12>-0.0352</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.2057</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="693">
         <PDBx:U11>0.2523</PDBx:U11>
         <PDBx:U12>-0.0267</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.2545</PDBx:U22>
         <PDBx:U23>-0.0186</PDBx:U23>
         <PDBx:U33>0.0902</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="694">
         <PDBx:U11>0.2205</PDBx:U11>
         <PDBx:U12>-0.0380</PDBx:U12>
         <PDBx:U13>0.0178</PDBx:U13>
         <PDBx:U22>0.2187</PDBx:U22>
         <PDBx:U23>-0.0171</PDBx:U23>
         <PDBx:U33>0.0649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="695">
         <PDBx:U11>0.3010</PDBx:U11>
         <PDBx:U12>-0.0333</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.3040</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.1347</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="696">
         <PDBx:U11>0.3457</PDBx:U11>
         <PDBx:U12>-0.0358</PDBx:U12>
         <PDBx:U13>0.0209</PDBx:U13>
         <PDBx:U22>0.3544</PDBx:U22>
         <PDBx:U23>-0.0272</PDBx:U23>
         <PDBx:U33>0.1823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="697">
         <PDBx:U11>0.1251</PDBx:U11>
         <PDBx:U12>-0.0253</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.1030</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="698">
         <PDBx:U11>0.1437</PDBx:U11>
         <PDBx:U12>-0.0285</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1169</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="699">
         <PDBx:U11>0.1412</PDBx:U11>
         <PDBx:U12>-0.0317</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1198</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.0398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="700">
         <PDBx:U11>0.0856</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.0684</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="701">
         <PDBx:U11>0.1696</PDBx:U11>
         <PDBx:U12>-0.0244</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1386</PDBx:U22>
         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.0503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="702">
         <PDBx:U11>0.2222</PDBx:U11>
         <PDBx:U12>-0.0225</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1860</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.0622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="703">
         <PDBx:U11>0.2564</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.2134</PDBx:U22>
         <PDBx:U23>0.0076</PDBx:U23>
         <PDBx:U33>0.0610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="704">
         <PDBx:U11>0.2469</PDBx:U11>
         <PDBx:U12>-0.0177</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.2115</PDBx:U22>
         <PDBx:U23>0.0072</PDBx:U23>
         <PDBx:U33>0.0650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="705">
         <PDBx:U11>0.2501</PDBx:U11>
         <PDBx:U12>-0.0226</PDBx:U12>
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         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>285</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>285</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="738">
         <PDBx:U11>0.1097</PDBx:U11>
         <PDBx:U12>-0.0196</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.0854</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="739">
         <PDBx:U11>0.1102</PDBx:U11>
         <PDBx:U12>-0.0235</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.0845</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.0419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="740">
         <PDBx:U11>0.1193</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.0857</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="741">
         <PDBx:U11>0.1627</PDBx:U11>
         <PDBx:U12>-0.0163</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.1237</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.0459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="742">
         <PDBx:U11>0.1609</PDBx:U11>
         <PDBx:U12>-0.0205</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1138</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="743">
         <PDBx:U11>0.1625</PDBx:U11>
         <PDBx:U12>-0.0125</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1212</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.0477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="744">
         <PDBx:U11>0.0706</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.0523</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="745">
         <PDBx:U11>0.0756</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.0635</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="746">
         <PDBx:U11>0.1149</PDBx:U11>
         <PDBx:U12>-0.0204</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.1071</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.0403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="747">
         <PDBx:U11>0.1096</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.1027</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="748">
         <PDBx:U11>0.0881</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.0804</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.0431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="749">
         <PDBx:U11>0.0880</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.0866</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="750">
         <PDBx:U11>0.1263</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.1246</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.0531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="751">
         <PDBx:U11>0.1133</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1183</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.0517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="752">
         <PDBx:U11>0.1498</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.1535</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.0587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="753">
         <PDBx:U11>0.1555</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.1661</PDBx:U22>
         <PDBx:U23>-0.0188</PDBx:U23>
         <PDBx:U33>0.0605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="754">
         <PDBx:U11>0.1373</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.1475</PDBx:U22>
         <PDBx:U23>-0.0161</PDBx:U23>
         <PDBx:U33>0.0558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="755">
         <PDBx:U11>0.0889</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.0839</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.0396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="756">
         <PDBx:U11>0.0739</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.0740</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="757">
         <PDBx:U11>0.1480</PDBx:U11>
         <PDBx:U12>-0.0314</PDBx:U12>
         <PDBx:U13>0.0148</PDBx:U13>
         <PDBx:U22>0.1421</PDBx:U22>
         <PDBx:U23>-0.0150</PDBx:U23>
         <PDBx:U33>0.0500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="758">
         <PDBx:U11>0.1694</PDBx:U11>
         <PDBx:U12>-0.0355</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.1673</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.0512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="759">
         <PDBx:U11>0.0801</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.0827</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.0415</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="760">
         <PDBx:U11>0.2043</PDBx:U11>
         <PDBx:U12>-0.0194</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.2123</PDBx:U22>
         <PDBx:U23>-0.0245</PDBx:U23>
         <PDBx:U33>0.0706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="761">
         <PDBx:U11>0.1912</PDBx:U11>
         <PDBx:U12>-0.0158</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.2001</PDBx:U22>
         <PDBx:U23>-0.0230</PDBx:U23>
         <PDBx:U33>0.0671</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="762">
         <PDBx:U11>0.3254</PDBx:U11>
         <PDBx:U12>-0.0193</PDBx:U12>
         <PDBx:U13>0.0163</PDBx:U13>
         <PDBx:U22>0.3366</PDBx:U22>
         <PDBx:U23>-0.0297</PDBx:U23>
         <PDBx:U33>0.1761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="763">
         <PDBx:U11>0.0870</PDBx:U11>
         <PDBx:U12>-0.0323</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.0718</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="764">
         <PDBx:U11>0.0970</PDBx:U11>
         <PDBx:U12>-0.0377</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.0733</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.0396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="765">
         <PDBx:U11>0.1682</PDBx:U11>
         <PDBx:U12>-0.0390</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>0.1424</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.0498</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="766">
         <PDBx:U11>0.1882</PDBx:U11>
         <PDBx:U12>-0.0451</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.1599</PDBx:U22>
         <PDBx:U23>-0.0155</PDBx:U23>
         <PDBx:U33>0.0441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="767">
         <PDBx:U11>0.1056</PDBx:U11>
         <PDBx:U12>-0.0354</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.0727</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.0391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="768">
         <PDBx:U11>0.1662</PDBx:U11>
         <PDBx:U12>-0.0407</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.1236</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.0427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="769">
         <PDBx:U11>0.2002</PDBx:U11>
         <PDBx:U12>-0.0453</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.1556</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.0468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="770">
         <PDBx:U11>0.1858</PDBx:U11>
         <PDBx:U12>-0.0413</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.1351</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="771">
         <PDBx:U11>0.2239</PDBx:U11>
         <PDBx:U12>-0.0507</PDBx:U12>
         <PDBx:U13>0.0170</PDBx:U13>
         <PDBx:U22>0.1685</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.0474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="772">
         <PDBx:U11>0.2218</PDBx:U11>
         <PDBx:U12>-0.0462</PDBx:U12>
         <PDBx:U13>0.0160</PDBx:U13>
         <PDBx:U22>0.1600</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.0404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="773">
         <PDBx:U11>0.2874</PDBx:U11>
         <PDBx:U12>-0.0511</PDBx:U12>
         <PDBx:U13>0.0195</PDBx:U13>
         <PDBx:U22>0.2231</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="774">
         <PDBx:U11>0.3675</PDBx:U11>
         <PDBx:U12>-0.0566</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.2908</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.1329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="775">
         <PDBx:U11>0.1202</PDBx:U11>
         <PDBx:U12>-0.0345</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.0951</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.0482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="776">
         <PDBx:U11>0.1158</PDBx:U11>
         <PDBx:U12>-0.0359</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.0889</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.0437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="777">
         <PDBx:U11>0.1912</PDBx:U11>
         <PDBx:U12>-0.0374</PDBx:U12>
         <PDBx:U13>0.0215</PDBx:U13>
         <PDBx:U22>0.1740</PDBx:U22>
         <PDBx:U23>-0.0185</PDBx:U23>
         <PDBx:U33>0.0558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="778">
         <PDBx:U11>0.1864</PDBx:U11>
         <PDBx:U12>-0.0413</PDBx:U12>
         <PDBx:U13>0.0227</PDBx:U13>
         <PDBx:U22>0.1679</PDBx:U22>
         <PDBx:U23>-0.0194</PDBx:U23>
         <PDBx:U33>0.0548</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="779">
         <PDBx:U11>0.1178</PDBx:U11>
         <PDBx:U12>-0.0303</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.0888</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.0410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="780">
         <PDBx:U11>0.1680</PDBx:U11>
         <PDBx:U12>-0.0277</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.1304</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="781">
         <PDBx:U11>0.1437</PDBx:U11>
         <PDBx:U12>-0.0226</PDBx:U12>
         <PDBx:U13>0.0104</PDBx:U13>
         <PDBx:U22>0.1070</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="782">
         <PDBx:U11>0.1795</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.1316</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.0403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="783">
         <PDBx:U11>0.1523</PDBx:U11>
         <PDBx:U12>-0.0352</PDBx:U12>
         <PDBx:U13>0.0174</PDBx:U13>
         <PDBx:U22>0.1444</PDBx:U22>
         <PDBx:U23>-0.0170</PDBx:U23>
         <PDBx:U33>0.0528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="784">
         <PDBx:U11>0.1615</PDBx:U11>
         <PDBx:U12>-0.0366</PDBx:U12>
         <PDBx:U13>0.0200</PDBx:U13>
         <PDBx:U22>0.1637</PDBx:U22>
         <PDBx:U23>-0.0230</PDBx:U23>
         <PDBx:U33>0.0583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="785">
         <PDBx:U11>0.2237</PDBx:U11>
         <PDBx:U12>-0.0431</PDBx:U12>
         <PDBx:U13>0.0297</PDBx:U13>
         <PDBx:U22>0.2269</PDBx:U22>
         <PDBx:U23>-0.0349</PDBx:U23>
         <PDBx:U33>0.0699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="786">
         <PDBx:U11>0.2597</PDBx:U11>
         <PDBx:U12>-0.0469</PDBx:U12>
         <PDBx:U13>0.0349</PDBx:U13>
         <PDBx:U22>0.2655</PDBx:U22>
         <PDBx:U23>-0.0422</PDBx:U23>
         <PDBx:U33>0.0890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="787">
         <PDBx:U11>0.1509</PDBx:U11>
         <PDBx:U12>-0.0315</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.1612</PDBx:U22>
         <PDBx:U23>-0.0239</PDBx:U23>
         <PDBx:U33>0.0565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="788">
         <PDBx:U11>0.3212</PDBx:U11>
         <PDBx:U12>-0.0247</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.3319</PDBx:U22>
         <PDBx:U23>-0.0345</PDBx:U23>
         <PDBx:U33>0.1681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="789">
         <PDBx:U11>0.0973</PDBx:U11>
         <PDBx:U12>-0.0266</PDBx:U12>
         <PDBx:U13>0.0121</PDBx:U13>
         <PDBx:U22>0.1169</PDBx:U22>
         <PDBx:U23>-0.0190</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="790">
         <PDBx:U11>0.1717</PDBx:U11>
         <PDBx:U12>-0.0220</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.1779</PDBx:U22>
         <PDBx:U23>-0.0194</PDBx:U23>
         <PDBx:U33>0.0763</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="791">
         <PDBx:U11>0.1875</PDBx:U11>
         <PDBx:U12>-0.0461</PDBx:U12>
         <PDBx:U13>0.0255</PDBx:U13>
         <PDBx:U22>0.1879</PDBx:U22>
         <PDBx:U23>-0.0283</PDBx:U23>
         <PDBx:U33>0.0614</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="792">
         <PDBx:U11>0.2098</PDBx:U11>
         <PDBx:U12>-0.0536</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.2111</PDBx:U22>
         <PDBx:U23>-0.0340</PDBx:U23>
         <PDBx:U33>0.0666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="793">
         <PDBx:U11>0.2778</PDBx:U11>
         <PDBx:U12>-0.0597</PDBx:U12>
         <PDBx:U13>0.0378</PDBx:U13>
         <PDBx:U22>0.2685</PDBx:U22>
         <PDBx:U23>-0.0381</PDBx:U23>
         <PDBx:U33>0.0874</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="794">
         <PDBx:U11>0.2969</PDBx:U11>
         <PDBx:U12>-0.0671</PDBx:U12>
         <PDBx:U13>0.0418</PDBx:U13>
         <PDBx:U22>0.2899</PDBx:U22>
         <PDBx:U23>-0.0432</PDBx:U23>
         <PDBx:U33>0.1027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="795">
         <PDBx:U11>0.1837</PDBx:U11>
         <PDBx:U12>-0.0542</PDBx:U12>
         <PDBx:U13>0.0263</PDBx:U13>
         <PDBx:U22>0.1849</PDBx:U22>
         <PDBx:U23>-0.0288</PDBx:U23>
         <PDBx:U33>0.0642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="796">
         <PDBx:U11>0.3140</PDBx:U11>
         <PDBx:U12>-0.0481</PDBx:U12>
         <PDBx:U13>0.0329</PDBx:U13>
         <PDBx:U22>0.3250</PDBx:U22>
         <PDBx:U23>-0.0428</PDBx:U23>
         <PDBx:U33>0.1451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="797">
         <PDBx:U11>0.6619</PDBx:U11>
         <PDBx:U12>-0.0498</PDBx:U12>
         <PDBx:U13>0.0327</PDBx:U13>
         <PDBx:U22>0.6708</PDBx:U22>
         <PDBx:U23>-0.0412</PDBx:U23>
         <PDBx:U33>0.4900</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="798">
         <PDBx:U11>0.8626</PDBx:U11>
         <PDBx:U12>-0.0441</PDBx:U12>
         <PDBx:U13>0.0300</PDBx:U13>
         <PDBx:U22>0.8778</PDBx:U22>
         <PDBx:U23>-0.0424</PDBx:U23>
         <PDBx:U33>0.6993</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="799">
         <PDBx:U11>1.1364</PDBx:U11>
         <PDBx:U12>-0.0450</PDBx:U12>
         <PDBx:U13>0.0298</PDBx:U13>
         <PDBx:U22>1.1519</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.9725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="800">
         <PDBx:U11>1.0279</PDBx:U11>
         <PDBx:U12>-0.0515</PDBx:U12>
         <PDBx:U13>0.0320</PDBx:U13>
         <PDBx:U22>1.0381</PDBx:U22>
         <PDBx:U23>-0.0406</PDBx:U23>
         <PDBx:U33>0.8553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="801">
         <PDBx:U11>1.0116</PDBx:U11>
         <PDBx:U12>-0.0396</PDBx:U12>
         <PDBx:U13>0.0272</PDBx:U13>
         <PDBx:U22>1.0323</PDBx:U22>
         <PDBx:U23>-0.0432</PDBx:U23>
         <PDBx:U33>0.8554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="802">
         <PDBx:U11>0.2190</PDBx:U11>
         <PDBx:U12>-0.0583</PDBx:U12>
         <PDBx:U13>0.0307</PDBx:U13>
         <PDBx:U22>0.1981</PDBx:U22>
         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.0549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="803">
         <PDBx:U11>0.2215</PDBx:U11>
         <PDBx:U12>-0.0643</PDBx:U12>
         <PDBx:U13>0.0308</PDBx:U13>
         <PDBx:U22>0.1880</PDBx:U22>
         <PDBx:U23>-0.0239</PDBx:U23>
         <PDBx:U33>0.0509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="804">
         <PDBx:U11>0.2926</PDBx:U11>
         <PDBx:U12>-0.0611</PDBx:U12>
         <PDBx:U13>0.0345</PDBx:U13>
         <PDBx:U22>0.2521</PDBx:U22>
         <PDBx:U23>-0.0244</PDBx:U23>
         <PDBx:U33>0.0819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="805">
         <PDBx:U11>0.2666</PDBx:U11>
         <PDBx:U12>-0.0540</PDBx:U12>
         <PDBx:U13>0.0319</PDBx:U13>
         <PDBx:U22>0.2284</PDBx:U22>
         <PDBx:U23>-0.0222</PDBx:U23>
         <PDBx:U33>0.0631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="806">
         <PDBx:U11>0.2390</PDBx:U11>
         <PDBx:U12>-0.0645</PDBx:U12>
         <PDBx:U13>0.0296</PDBx:U13>
         <PDBx:U22>0.1958</PDBx:U22>
         <PDBx:U23>-0.0200</PDBx:U23>
         <PDBx:U33>0.0519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="807">
         <PDBx:U11>0.2452</PDBx:U11>
         <PDBx:U12>-0.0660</PDBx:U12>
         <PDBx:U13>0.0322</PDBx:U13>
         <PDBx:U22>0.2078</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.0453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="808">
         <PDBx:U11>0.2862</PDBx:U11>
         <PDBx:U12>-0.0739</PDBx:U12>
         <PDBx:U13>0.0384</PDBx:U13>
         <PDBx:U22>0.2534</PDBx:U22>
         <PDBx:U23>-0.0303</PDBx:U23>
         <PDBx:U33>0.0682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="809">
         <PDBx:U11>0.2567</PDBx:U11>
         <PDBx:U12>-0.0599</PDBx:U12>
         <PDBx:U13>0.0308</PDBx:U13>
         <PDBx:U22>0.2206</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.0467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="810">
         <PDBx:U11>0.3194</PDBx:U11>
         <PDBx:U12>-0.0758</PDBx:U12>
         <PDBx:U13>0.0392</PDBx:U13>
         <PDBx:U22>0.2919</PDBx:U22>
         <PDBx:U23>-0.0326</PDBx:U23>
         <PDBx:U33>0.1029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="811">
         <PDBx:U11>0.2732</PDBx:U11>
         <PDBx:U12>-0.0616</PDBx:U12>
         <PDBx:U13>0.0315</PDBx:U13>
         <PDBx:U22>0.2419</PDBx:U22>
         <PDBx:U23>-0.0231</PDBx:U23>
         <PDBx:U33>0.0645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="812">
         <PDBx:U11>0.3762</PDBx:U11>
         <PDBx:U12>-0.0693</PDBx:U12>
         <PDBx:U13>0.0356</PDBx:U13>
         <PDBx:U22>0.3495</PDBx:U22>
         <PDBx:U23>-0.0289</PDBx:U23>
         <PDBx:U33>0.1646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="813">
         <PDBx:U11>0.4170</PDBx:U11>
         <PDBx:U12>-0.0710</PDBx:U12>
         <PDBx:U13>0.0364</PDBx:U13>
         <PDBx:U22>0.3956</PDBx:U22>
         <PDBx:U23>-0.0313</PDBx:U23>
         <PDBx:U33>0.2073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="814">
         <PDBx:U11>0.3016</PDBx:U11>
         <PDBx:U12>-0.0672</PDBx:U12>
         <PDBx:U13>0.0357</PDBx:U13>
         <PDBx:U22>0.2506</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.0799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="815">
         <PDBx:U11>0.2990</PDBx:U11>
         <PDBx:U12>-0.0656</PDBx:U12>
         <PDBx:U13>0.0337</PDBx:U13>
         <PDBx:U22>0.2378</PDBx:U22>
         <PDBx:U23>-0.0193</PDBx:U23>
         <PDBx:U33>0.0732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="816">
         <PDBx:U11>0.3535</PDBx:U11>
         <PDBx:U12>-0.0659</PDBx:U12>
         <PDBx:U13>0.0298</PDBx:U13>
         <PDBx:U22>0.2790</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.1185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="817">
         <PDBx:U11>0.3735</PDBx:U11>
         <PDBx:U12>-0.0699</PDBx:U12>
         <PDBx:U13>0.0303</PDBx:U13>
         <PDBx:U22>0.2975</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.1332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="818">
         <PDBx:U11>0.3854</PDBx:U11>
         <PDBx:U12>-0.0727</PDBx:U12>
         <PDBx:U13>0.0373</PDBx:U13>
         <PDBx:U22>0.3202</PDBx:U22>
         <PDBx:U23>-0.0222</PDBx:U23>
         <PDBx:U33>0.1524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="819">
         <PDBx:U11>0.3998</PDBx:U11>
         <PDBx:U12>-0.0818</PDBx:U12>
         <PDBx:U13>0.0398</PDBx:U13>
         <PDBx:U22>0.3291</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.1554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="820">
         <PDBx:U11>0.3388</PDBx:U11>
         <PDBx:U12>-0.0722</PDBx:U12>
         <PDBx:U13>0.0407</PDBx:U13>
         <PDBx:U22>0.2869</PDBx:U22>
         <PDBx:U23>-0.0284</PDBx:U23>
         <PDBx:U33>0.1150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="821">
         <PDBx:U11>0.2981</PDBx:U11>
         <PDBx:U12>-0.0615</PDBx:U12>
         <PDBx:U13>0.0259</PDBx:U13>
         <PDBx:U22>0.2145</PDBx:U22>
         <PDBx:U23>-0.0088</PDBx:U23>
         <PDBx:U33>0.0617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="822">
         <PDBx:U11>0.3002</PDBx:U11>
         <PDBx:U12>-0.0608</PDBx:U12>
         <PDBx:U13>0.0212</PDBx:U13>
         <PDBx:U22>0.2036</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.0565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="823">
         <PDBx:U11>0.3628</PDBx:U11>
         <PDBx:U12>-0.0646</PDBx:U12>
         <PDBx:U13>0.0199</PDBx:U13>
         <PDBx:U22>0.2511</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.1070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="824">
         <PDBx:U11>0.4077</PDBx:U11>
         <PDBx:U12>-0.0659</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.2969</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="825">
         <PDBx:U11>0.3342</PDBx:U11>
         <PDBx:U12>-0.0515</PDBx:U12>
         <PDBx:U13>0.0168</PDBx:U13>
         <PDBx:U22>0.2400</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="826">
         <PDBx:U11>0.3132</PDBx:U11>
         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>0.0181</PDBx:U13>
         <PDBx:U22>0.2322</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0874</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="827">
         <PDBx:U11>0.3294</PDBx:U11>
         <PDBx:U12>-0.0461</PDBx:U12>
         <PDBx:U13>0.0156</PDBx:U13>
         <PDBx:U22>0.2362</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.1010</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="828">
         <PDBx:U11>0.2944</PDBx:U11>
         <PDBx:U12>-0.0661</PDBx:U12>
         <PDBx:U13>0.0146</PDBx:U13>
         <PDBx:U22>0.1684</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.0429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="829">
         <PDBx:U11>0.3082</PDBx:U11>
         <PDBx:U12>-0.0687</PDBx:U12>
         <PDBx:U13>0.0121</PDBx:U13>
         <PDBx:U22>0.1655</PDBx:U22>
         <PDBx:U23>0.0048</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="830">
         <PDBx:U11>0.3661</PDBx:U11>
         <PDBx:U12>-0.0592</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.2212</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.0962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="831">
         <PDBx:U11>0.3298</PDBx:U11>
         <PDBx:U12>-0.0524</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.1965</PDBx:U22>
         <PDBx:U23>0.0076</PDBx:U23>
         <PDBx:U33>0.0725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="832">
         <PDBx:U11>0.3697</PDBx:U11>
         <PDBx:U12>-0.0753</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.2116</PDBx:U22>
         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.0750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="833">
         <PDBx:U11>0.3649</PDBx:U11>
         <PDBx:U12>-0.0704</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.2070</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.0728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="834">
         <PDBx:U11>0.3944</PDBx:U11>
         <PDBx:U12>-0.0858</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.2386</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.0912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="835">
         <PDBx:U11>0.3586</PDBx:U11>
         <PDBx:U12>-0.0588</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1990</PDBx:U22>
         <PDBx:U23>0.0105</PDBx:U23>
         <PDBx:U33>0.0815</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="836">
         <PDBx:U11>0.3555</PDBx:U11>
         <PDBx:U12>-0.0500</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1931</PDBx:U22>
         <PDBx:U23>0.0122</PDBx:U23>
         <PDBx:U33>0.0858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="837">
         <PDBx:U11>0.3532</PDBx:U11>
         <PDBx:U12>-0.0457</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.1899</PDBx:U22>
         <PDBx:U23>0.0149</PDBx:U23>
         <PDBx:U33>0.0850</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="838">
         <PDBx:U11>0.2851</PDBx:U11>
         <PDBx:U12>-0.0384</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.1317</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.0461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="839">
         <PDBx:U11>0.4408</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.2612</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.1619</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="840">
         <PDBx:U11>0.4468</PDBx:U11>
         <PDBx:U12>-0.0427</PDBx:U12>
         <PDBx:U13>-0.0142</PDBx:U13>
         <PDBx:U22>0.2600</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.1718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="841">
         <PDBx:U11>0.4329</PDBx:U11>
         <PDBx:U12>-0.0521</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.2579</PDBx:U22>
         <PDBx:U23>0.0105</PDBx:U23>
         <PDBx:U33>0.1582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="842">
         <PDBx:U11>0.3493</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.1747</PDBx:U22>
         <PDBx:U23>0.0176</PDBx:U23>
         <PDBx:U33>0.0675</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="843">
         <PDBx:U11>0.3343</PDBx:U11>
         <PDBx:U12>-0.0481</PDBx:U12>
         <PDBx:U13>-0.0135</PDBx:U13>
         <PDBx:U22>0.1578</PDBx:U22>
         <PDBx:U23>0.0203</PDBx:U23>
         <PDBx:U33>0.0518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="844">
         <PDBx:U11>0.3548</PDBx:U11>
         <PDBx:U12>-0.0452</PDBx:U12>
         <PDBx:U13>-0.0096</PDBx:U13>
         <PDBx:U22>0.1969</PDBx:U22>
         <PDBx:U23>0.0182</PDBx:U23>
         <PDBx:U33>0.0852</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="845">
         <PDBx:U11>0.3379</PDBx:U11>
         <PDBx:U12>-0.0383</PDBx:U12>
         <PDBx:U13>-0.0127</PDBx:U13>
         <PDBx:U22>0.1850</PDBx:U22>
         <PDBx:U23>0.0188</PDBx:U23>
         <PDBx:U33>0.0771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="846">
         <PDBx:U11>0.3640</PDBx:U11>
         <PDBx:U12>-0.0563</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.1739</PDBx:U22>
         <PDBx:U23>0.0230</PDBx:U23>
         <PDBx:U33>0.0638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="847">
         <PDBx:U11>0.5599</PDBx:U11>
         <PDBx:U12>-0.0623</PDBx:U12>
         <PDBx:U13>-0.0170</PDBx:U13>
         <PDBx:U22>0.3508</PDBx:U22>
         <PDBx:U23>0.0248</PDBx:U23>
         <PDBx:U33>0.2435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="848">
         <PDBx:U11>0.9259</PDBx:U11>
         <PDBx:U12>-0.0577</PDBx:U12>
         <PDBx:U13>-0.0264</PDBx:U13>
         <PDBx:U22>0.6991</PDBx:U22>
         <PDBx:U23>0.0284</PDBx:U23>
         <PDBx:U33>0.6031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="849">
         <PDBx:U11>0.8806</PDBx:U11>
         <PDBx:U12>-0.0583</PDBx:U12>
         <PDBx:U13>-0.0316</PDBx:U13>
         <PDBx:U22>0.6436</PDBx:U22>
         <PDBx:U23>0.0318</PDBx:U23>
         <PDBx:U33>0.5488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="850">
         <PDBx:U11>0.8820</PDBx:U11>
         <PDBx:U12>-0.0539</PDBx:U12>
         <PDBx:U13>-0.0286</PDBx:U13>
         <PDBx:U22>0.6506</PDBx:U22>
         <PDBx:U23>0.0278</PDBx:U23>
         <PDBx:U33>0.5624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="851">
         <PDBx:U11>0.2863</PDBx:U11>
         <PDBx:U12>-0.0502</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.1390</PDBx:U22>
         <PDBx:U23>0.0116</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>0.0067</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>303</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>303</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>303</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:U13>-0.0191</PDBx:U13>
         <PDBx:U22>0.1118</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.0451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>303</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="869">
         <PDBx:U11>0.3028</PDBx:U11>
         <PDBx:U12>-0.0118</PDBx:U12>
         <PDBx:U13>-0.0283</PDBx:U13>
         <PDBx:U22>0.1499</PDBx:U22>
         <PDBx:U23>0.0160</PDBx:U23>
         <PDBx:U33>0.0728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>303</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="870">
         <PDBx:U11>0.3495</PDBx:U11>
         <PDBx:U12>-0.0224</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>0.1756</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.1001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>303</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="871">
         <PDBx:U11>0.2266</PDBx:U11>
         <PDBx:U12>-0.0226</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.0977</PDBx:U22>
         <PDBx:U23>0.0091</PDBx:U23>
         <PDBx:U33>0.0453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="872">
         <PDBx:U11>0.2202</PDBx:U11>
         <PDBx:U12>-0.0221</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.0965</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.0413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="873">
         <PDBx:U11>0.2462</PDBx:U11>
         <PDBx:U12>-0.0186</PDBx:U12>
         <PDBx:U13>-0.0104</PDBx:U13>
         <PDBx:U22>0.1381</PDBx:U22>
         <PDBx:U23>0.0123</PDBx:U23>
         <PDBx:U33>0.0492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="874">
         <PDBx:U11>0.2252</PDBx:U11>
         <PDBx:U12>-0.0142</PDBx:U12>
         <PDBx:U13>-0.0117</PDBx:U13>
         <PDBx:U22>0.1220</PDBx:U22>
         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.0435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="875">
         <PDBx:U11>0.2738</PDBx:U11>
         <PDBx:U12>-0.0294</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.1454</PDBx:U22>
         <PDBx:U23>0.0171</PDBx:U23>
         <PDBx:U33>0.0420</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="876">
         <PDBx:U11>0.3853</PDBx:U11>
         <PDBx:U12>-0.0324</PDBx:U12>
         <PDBx:U13>-0.0179</PDBx:U13>
         <PDBx:U22>0.2398</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.1299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="877">
         <PDBx:U11>0.3735</PDBx:U11>
         <PDBx:U12>-0.0415</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.2238</PDBx:U22>
         <PDBx:U23>0.0226</PDBx:U23>
         <PDBx:U33>0.1057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="878">
         <PDBx:U11>0.4205</PDBx:U11>
         <PDBx:U12>-0.0421</PDBx:U12>
         <PDBx:U13>-0.0151</PDBx:U13>
         <PDBx:U22>0.2747</PDBx:U22>
         <PDBx:U23>0.0235</PDBx:U23>
         <PDBx:U33>0.1522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="879">
         <PDBx:U11>0.4089</PDBx:U11>
         <PDBx:U12>-0.0509</PDBx:U12>
         <PDBx:U13>-0.0147</PDBx:U13>
         <PDBx:U22>0.2531</PDBx:U22>
         <PDBx:U23>0.0251</PDBx:U23>
         <PDBx:U33>0.1251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="880">
         <PDBx:U11>0.1824</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>-0.0047</PDBx:U13>
         <PDBx:U22>0.0827</PDBx:U22>
         <PDBx:U23>0.0049</PDBx:U23>
         <PDBx:U33>0.0403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="881">
         <PDBx:U11>0.1615</PDBx:U11>
         <PDBx:U12>-0.0181</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.0753</PDBx:U22>
         <PDBx:U23>0.0033</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="882">
         <PDBx:U11>0.1848</PDBx:U11>
         <PDBx:U12>-0.0123</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1023</PDBx:U22>
         <PDBx:U23>0.0052</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="883">
         <PDBx:U11>0.1510</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.0765</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="884">
         <PDBx:U11>0.1551</PDBx:U11>
         <PDBx:U12>-0.0214</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.0759</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="885">
         <PDBx:U11>0.2051</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1237</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="886">
         <PDBx:U11>0.1816</PDBx:U11>
         <PDBx:U12>-0.0313</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.1056</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="887">
         <PDBx:U11>0.2412</PDBx:U11>
         <PDBx:U12>-0.0284</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1658</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.0473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="888">
         <PDBx:U11>0.1399</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.0526</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="889">
         <PDBx:U11>0.1448</PDBx:U11>
         <PDBx:U12>-0.0064</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.0614</PDBx:U22>
         <PDBx:U23>0.0017</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="890">
         <PDBx:U11>0.1854</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.0997</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.0472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="891">
         <PDBx:U11>0.1511</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.0738</PDBx:U22>
         <PDBx:U23>0.0015</PDBx:U23>
         <PDBx:U33>0.0477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="892">
         <PDBx:U11>0.1650</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>-0.0051</PDBx:U13>
         <PDBx:U22>0.0763</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.0396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="893">
         <PDBx:U11>0.1384</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.0416</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="894">
         <PDBx:U11>0.1420</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>-0.0119</PDBx:U13>
         <PDBx:U22>0.0422</PDBx:U22>
         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="895">
         <PDBx:U11>0.1947</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.1027</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.0494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="896">
         <PDBx:U11>0.1515</PDBx:U11>
         <PDBx:U12>0.0066</PDBx:U12>
         <PDBx:U13>-0.0137</PDBx:U13>
         <PDBx:U22>0.0644</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.0434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="897">
         <PDBx:U11>0.1606</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>-0.0168</PDBx:U13>
         <PDBx:U22>0.0456</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.0406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="898">
         <PDBx:U11>0.1979</PDBx:U11>
         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>-0.0262</PDBx:U13>
         <PDBx:U22>0.0783</PDBx:U22>
         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.0461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="899">
         <PDBx:U11>0.1836</PDBx:U11>
         <PDBx:U12>0.0114</PDBx:U12>
         <PDBx:U13>-0.0272</PDBx:U13>
         <PDBx:U22>0.0683</PDBx:U22>
         <PDBx:U23>0.0015</PDBx:U23>
         <PDBx:U33>0.0462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="900">
         <PDBx:U11>0.2261</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>-0.0340</PDBx:U13>
         <PDBx:U22>0.0899</PDBx:U22>
         <PDBx:U23>0.0095</PDBx:U23>
         <PDBx:U33>0.0467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="934">
         <PDBx:U11>0.1828</PDBx:U11>
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         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1592</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.0583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="935">
         <PDBx:U11>0.1936</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
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         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.0545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="936">
         <PDBx:U11>0.2353</PDBx:U11>
         <PDBx:U12>0.0080</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.2111</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.1000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="937">
         <PDBx:U11>0.1230</PDBx:U11>
         <PDBx:U12>0.0176</PDBx:U12>
         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.0885</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.0462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="938">
         <PDBx:U11>0.1272</PDBx:U11>
         <PDBx:U12>0.0215</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.0951</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.0473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="939">
         <PDBx:U11>0.1584</PDBx:U11>
         <PDBx:U12>0.0218</PDBx:U12>
         <PDBx:U13>-0.0164</PDBx:U13>
         <PDBx:U22>0.1305</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.0540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="940">
         <PDBx:U11>0.0929</PDBx:U11>
         <PDBx:U12>0.0238</PDBx:U12>
         <PDBx:U13>-0.0104</PDBx:U13>
         <PDBx:U22>0.0737</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.0420</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="941">
         <PDBx:U11>0.1579</PDBx:U11>
         <PDBx:U12>0.0242</PDBx:U12>
         <PDBx:U13>-0.0206</PDBx:U13>
         <PDBx:U22>0.1162</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.0513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="942">
         <PDBx:U11>0.1407</PDBx:U11>
         <PDBx:U12>0.0206</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.1085</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.0492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="943">
         <PDBx:U11>0.1261</PDBx:U11>
         <PDBx:U12>0.0210</PDBx:U12>
         <PDBx:U13>-0.0123</PDBx:U13>
         <PDBx:U22>0.0977</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.0490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="944">
         <PDBx:U11>0.1383</PDBx:U11>
         <PDBx:U12>0.0182</PDBx:U12>
         <PDBx:U13>-0.0105</PDBx:U13>
         <PDBx:U22>0.1196</PDBx:U22>
         <PDBx:U23>-0.0087</PDBx:U23>
         <PDBx:U33>0.0503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="945">
         <PDBx:U11>0.0941</PDBx:U11>
         <PDBx:U12>0.0194</PDBx:U12>
         <PDBx:U13>-0.0072</PDBx:U13>
         <PDBx:U22>0.0827</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.0465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="946">
         <PDBx:U11>0.1466</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>-0.0137</PDBx:U13>
         <PDBx:U22>0.1120</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="947">
         <PDBx:U11>0.1938</PDBx:U11>
         <PDBx:U12>0.0194</PDBx:U12>
         <PDBx:U13>-0.0201</PDBx:U13>
         <PDBx:U22>0.1637</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.0642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="948">
         <PDBx:U11>0.2217</PDBx:U11>
         <PDBx:U12>0.0229</PDBx:U12>
         <PDBx:U13>-0.0259</PDBx:U13>
         <PDBx:U22>0.1918</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.0893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="949">
         <PDBx:U11>0.2344</PDBx:U11>
         <PDBx:U12>0.0169</PDBx:U12>
         <PDBx:U13>-0.0177</PDBx:U13>
         <PDBx:U22>0.2086</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.0963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0087</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0200</PDBx:U13>
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         <PDBx:U23>-0.0062</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.0443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="953">
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         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.0893</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="954">
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         <PDBx:U12>0.0122</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1153</PDBx:U22>
         <PDBx:U23>-0.0095</PDBx:U23>
         <PDBx:U33>0.0507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1365</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.0532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="956">
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         <PDBx:U12>0.0093</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1052</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="957">
         <PDBx:U11>0.2299</PDBx:U11>
         <PDBx:U12>0.0064</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.2178</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.0917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="958">
         <PDBx:U11>0.2165</PDBx:U11>
         <PDBx:U12>0.0060</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.2026</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.0746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="959">
         <PDBx:U11>0.2932</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.2794</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.1517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="960">
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         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.0630</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="961">
         <PDBx:U11>0.0766</PDBx:U11>
         <PDBx:U12>0.0133</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.0804</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.0479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="962">
         <PDBx:U11>0.1754</PDBx:U11>
         <PDBx:U12>0.0159</PDBx:U12>
         <PDBx:U13>-0.0073</PDBx:U13>
         <PDBx:U22>0.1805</PDBx:U22>
         <PDBx:U23>-0.0308</PDBx:U23>
         <PDBx:U33>0.0716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="963">
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         <PDBx:U12>0.0147</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.1944</PDBx:U22>
         <PDBx:U23>-0.0372</PDBx:U23>
         <PDBx:U33>0.0831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.0683</PDBx:U11>
         <PDBx:U12>0.0144</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.0698</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.0440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1018</PDBx:U11>
         <PDBx:U12>0.0106</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1002</PDBx:U22>
         <PDBx:U23>-0.0107</PDBx:U23>
         <PDBx:U33>0.0475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="966">
         <PDBx:U11>0.1239</PDBx:U11>
         <PDBx:U12>0.0108</PDBx:U12>
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         <PDBx:U22>0.1193</PDBx:U22>
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         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0346</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="983">
         <PDBx:U11>0.2647</PDBx:U11>
         <PDBx:U12>0.0150</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.3123</PDBx:U22>
         <PDBx:U23>-0.0619</PDBx:U23>
         <PDBx:U33>0.1912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="984">
         <PDBx:U11>0.5472</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.6071</PDBx:U22>
         <PDBx:U23>-0.0721</PDBx:U23>
         <PDBx:U33>0.4823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="985">
         <PDBx:U11>0.3063</PDBx:U11>
         <PDBx:U12>0.0142</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.3708</PDBx:U22>
         <PDBx:U23>-0.0786</PDBx:U23>
         <PDBx:U33>0.2502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="986">
         <PDBx:U11>0.5117</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.5769</PDBx:U22>
         <PDBx:U23>-0.0742</PDBx:U23>
         <PDBx:U33>0.4450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="987">
         <PDBx:U11>0.1819</PDBx:U11>
         <PDBx:U12>0.0253</PDBx:U12>
         <PDBx:U13>-0.0185</PDBx:U13>
         <PDBx:U22>0.2093</PDBx:U22>
         <PDBx:U23>-0.0485</PDBx:U23>
         <PDBx:U33>0.0999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="988">
         <PDBx:U11>0.1923</PDBx:U11>
         <PDBx:U12>0.0300</PDBx:U12>
         <PDBx:U13>-0.0245</PDBx:U13>
         <PDBx:U22>0.2194</PDBx:U22>
         <PDBx:U23>-0.0504</PDBx:U23>
         <PDBx:U33>0.1141</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="989">
         <PDBx:U11>0.2360</PDBx:U11>
         <PDBx:U12>0.0283</PDBx:U12>
         <PDBx:U13>-0.0219</PDBx:U13>
         <PDBx:U22>0.2747</PDBx:U22>
         <PDBx:U23>-0.0573</PDBx:U23>
         <PDBx:U33>0.1642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="990">
         <PDBx:U11>0.2461</PDBx:U11>
         <PDBx:U12>0.0235</PDBx:U12>
         <PDBx:U13>-0.0168</PDBx:U13>
         <PDBx:U22>0.2872</PDBx:U22>
         <PDBx:U23>-0.0552</PDBx:U23>
         <PDBx:U33>0.1694</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="991">
         <PDBx:U11>0.2401</PDBx:U11>
         <PDBx:U12>0.0312</PDBx:U12>
         <PDBx:U13>-0.0279</PDBx:U13>
         <PDBx:U22>0.2567</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.1525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="992">
         <PDBx:U11>0.2501</PDBx:U11>
         <PDBx:U12>0.0300</PDBx:U12>
         <PDBx:U13>-0.0273</PDBx:U13>
         <PDBx:U22>0.2566</PDBx:U22>
         <PDBx:U23>-0.0348</PDBx:U23>
         <PDBx:U33>0.1538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="993">
         <PDBx:U11>0.2970</PDBx:U11>
         <PDBx:U12>0.0371</PDBx:U12>
         <PDBx:U13>-0.0361</PDBx:U13>
         <PDBx:U22>0.3106</PDBx:U22>
         <PDBx:U23>-0.0440</PDBx:U23>
         <PDBx:U33>0.2131</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="994">
         <PDBx:U11>0.2209</PDBx:U11>
         <PDBx:U12>0.0291</PDBx:U12>
         <PDBx:U13>-0.0286</PDBx:U13>
         <PDBx:U22>0.2186</PDBx:U22>
         <PDBx:U23>-0.0269</PDBx:U23>
         <PDBx:U33>0.1145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="995">
         <PDBx:U11>0.2008</PDBx:U11>
         <PDBx:U12>0.0317</PDBx:U12>
         <PDBx:U13>-0.0250</PDBx:U13>
         <PDBx:U22>0.2472</PDBx:U22>
         <PDBx:U23>-0.0661</PDBx:U23>
         <PDBx:U33>0.1403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="996">
         <PDBx:U11>0.1966</PDBx:U11>
         <PDBx:U12>0.0298</PDBx:U12>
         <PDBx:U13>-0.0223</PDBx:U13>
         <PDBx:U22>0.2557</PDBx:U22>
         <PDBx:U23>-0.0745</PDBx:U23>
         <PDBx:U33>0.1436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="997">
         <PDBx:U11>0.2555</PDBx:U11>
         <PDBx:U12>0.0327</PDBx:U12>
         <PDBx:U13>-0.0266</PDBx:U13>
         <PDBx:U22>0.3141</PDBx:U22>
         <PDBx:U23>-0.0736</PDBx:U23>
         <PDBx:U33>0.2025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="998">
         <PDBx:U11>0.2484</PDBx:U11>
         <PDBx:U12>0.0380</PDBx:U12>
         <PDBx:U13>-0.0336</PDBx:U13>
         <PDBx:U22>0.2988</PDBx:U22>
         <PDBx:U23>-0.0701</PDBx:U23>
         <PDBx:U33>0.1939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="999">
         <PDBx:U11>0.2570</PDBx:U11>
         <PDBx:U12>0.0319</PDBx:U12>
         <PDBx:U13>-0.0234</PDBx:U13>
         <PDBx:U22>0.3261</PDBx:U22>
         <PDBx:U23>-0.0858</PDBx:U23>
         <PDBx:U33>0.2176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1000">
         <PDBx:U11>0.2487</PDBx:U11>
         <PDBx:U12>0.0287</PDBx:U12>
         <PDBx:U13>-0.0196</PDBx:U13>
         <PDBx:U22>0.3322</PDBx:U22>
         <PDBx:U23>-0.0955</PDBx:U23>
         <PDBx:U33>0.2173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1001">
         <PDBx:U11>0.2615</PDBx:U11>
         <PDBx:U12>0.0290</PDBx:U12>
         <PDBx:U13>-0.0195</PDBx:U13>
         <PDBx:U22>0.3300</PDBx:U22>
         <PDBx:U23>-0.0858</PDBx:U23>
         <PDBx:U33>0.2213</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1002">
         <PDBx:U11>0.2039</PDBx:U11>
         <PDBx:U12>0.0287</PDBx:U12>
         <PDBx:U13>-0.0222</PDBx:U13>
         <PDBx:U22>0.2700</PDBx:U22>
         <PDBx:U23>-0.0761</PDBx:U23>
         <PDBx:U33>0.1508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1003">
         <PDBx:U11>0.2226</PDBx:U11>
         <PDBx:U12>0.0308</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>0.2899</PDBx:U22>
         <PDBx:U23>-0.0761</PDBx:U23>
         <PDBx:U33>0.1700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1004">
         <PDBx:U11>0.2895</PDBx:U11>
         <PDBx:U12>0.0248</PDBx:U12>
         <PDBx:U13>-0.0191</PDBx:U13>
         <PDBx:U22>0.3593</PDBx:U22>
         <PDBx:U23>-0.0736</PDBx:U23>
         <PDBx:U33>0.2303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1005">
         <PDBx:U11>0.3036</PDBx:U11>
         <PDBx:U12>0.0188</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.3743</PDBx:U22>
         <PDBx:U23>-0.0724</PDBx:U23>
         <PDBx:U33>0.2397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1006">
         <PDBx:U11>0.2725</PDBx:U11>
         <PDBx:U12>0.0262</PDBx:U12>
         <PDBx:U13>-0.0215</PDBx:U13>
         <PDBx:U22>0.3431</PDBx:U22>
         <PDBx:U23>-0.0730</PDBx:U23>
         <PDBx:U33>0.2129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1007">
         <PDBx:U11>0.2762</PDBx:U11>
         <PDBx:U12>0.0207</PDBx:U12>
         <PDBx:U13>-0.0160</PDBx:U13>
         <PDBx:U22>0.3485</PDBx:U22>
         <PDBx:U23>-0.0705</PDBx:U23>
         <PDBx:U33>0.2102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1008">
         <PDBx:U11>0.3247</PDBx:U11>
         <PDBx:U12>0.0185</PDBx:U12>
         <PDBx:U13>-0.0142</PDBx:U13>
         <PDBx:U22>0.3853</PDBx:U22>
         <PDBx:U23>-0.0595</PDBx:U23>
         <PDBx:U33>0.2463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1009">
         <PDBx:U11>0.3412</PDBx:U11>
         <PDBx:U12>0.0129</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.4012</PDBx:U22>
         <PDBx:U23>-0.0570</PDBx:U23>
         <PDBx:U33>0.2565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1010">
         <PDBx:U11>0.4783</PDBx:U11>
         <PDBx:U12>0.0227</PDBx:U12>
         <PDBx:U13>-0.0187</PDBx:U13>
         <PDBx:U22>0.5559</PDBx:U22>
         <PDBx:U23>-0.0738</PDBx:U23>
         <PDBx:U33>0.4161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1011">
         <PDBx:U11>0.5063</PDBx:U11>
         <PDBx:U12>0.0259</PDBx:U12>
         <PDBx:U13>-0.0216</PDBx:U13>
         <PDBx:U22>0.5947</PDBx:U22>
         <PDBx:U23>-0.0847</PDBx:U23>
         <PDBx:U33>0.4571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1012">
         <PDBx:U11>0.4810</PDBx:U11>
         <PDBx:U12>0.0164</PDBx:U12>
         <PDBx:U13>-0.0122</PDBx:U13>
         <PDBx:U22>0.5624</PDBx:U22>
         <PDBx:U23>-0.0735</PDBx:U23>
         <PDBx:U33>0.4140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1013">
         <PDBx:U11>0.2569</PDBx:U11>
         <PDBx:U12>0.0228</PDBx:U12>
         <PDBx:U13>-0.0197</PDBx:U13>
         <PDBx:U22>0.3078</PDBx:U22>
         <PDBx:U23>-0.0536</PDBx:U23>
         <PDBx:U33>0.1750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1014">
         <PDBx:U11>0.2315</PDBx:U11>
         <PDBx:U12>0.0212</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.2718</PDBx:U22>
         <PDBx:U23>-0.0443</PDBx:U23>
         <PDBx:U33>0.1392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1015">
         <PDBx:U11>0.2843</PDBx:U11>
         <PDBx:U12>0.0217</PDBx:U12>
         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.3209</PDBx:U22>
         <PDBx:U23>-0.0435</PDBx:U23>
         <PDBx:U33>0.1921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1016">
         <PDBx:U11>0.2781</PDBx:U11>
         <PDBx:U12>0.0235</PDBx:U12>
         <PDBx:U13>-0.0212</PDBx:U13>
         <PDBx:U22>0.3056</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.1810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1017">
         <PDBx:U11>0.2451</PDBx:U11>
         <PDBx:U12>0.0243</PDBx:U12>
         <PDBx:U13>-0.0241</PDBx:U13>
         <PDBx:U22>0.2773</PDBx:U22>
         <PDBx:U23>-0.0386</PDBx:U23>
         <PDBx:U33>0.1477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1018">
         <PDBx:U11>0.2918</PDBx:U11>
         <PDBx:U12>0.0234</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.3275</PDBx:U22>
         <PDBx:U23>-0.0388</PDBx:U23>
         <PDBx:U33>0.1936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1019">
         <PDBx:U11>0.3511</PDBx:U11>
         <PDBx:U12>0.0178</PDBx:U12>
         <PDBx:U13>-0.0174</PDBx:U13>
         <PDBx:U22>0.3872</PDBx:U22>
         <PDBx:U23>-0.0355</PDBx:U23>
         <PDBx:U33>0.2466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1020">
         <PDBx:U11>0.3169</PDBx:U11>
         <PDBx:U12>0.0151</PDBx:U12>
         <PDBx:U13>-0.0141</PDBx:U13>
         <PDBx:U22>0.3478</PDBx:U22>
         <PDBx:U23>-0.0307</PDBx:U23>
         <PDBx:U33>0.2062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1021">
         <PDBx:U11>0.2151</PDBx:U11>
         <PDBx:U12>0.0162</PDBx:U12>
         <PDBx:U13>-0.0158</PDBx:U13>
         <PDBx:U22>0.2572</PDBx:U22>
         <PDBx:U23>-0.0382</PDBx:U23>
         <PDBx:U33>0.1121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1022">
         <PDBx:U11>0.2122</PDBx:U11>
         <PDBx:U12>0.0192</PDBx:U12>
         <PDBx:U13>-0.0145</PDBx:U13>
         <PDBx:U22>0.2563</PDBx:U22>
         <PDBx:U23>-0.0494</PDBx:U23>
         <PDBx:U33>0.1251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1023">
         <PDBx:U11>0.2028</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>-0.0135</PDBx:U13>
         <PDBx:U22>0.2454</PDBx:U22>
         <PDBx:U23>-0.0500</PDBx:U23>
         <PDBx:U33>0.1169</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1024">
         <PDBx:U11>0.2264</PDBx:U11>
         <PDBx:U12>0.0155</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.2618</PDBx:U22>
         <PDBx:U23>-0.0428</PDBx:U23>
         <PDBx:U33>0.1310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1025">
         <PDBx:U11>0.2450</PDBx:U11>
         <PDBx:U12>0.0114</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.2796</PDBx:U22>
         <PDBx:U23>-0.0396</PDBx:U23>
         <PDBx:U33>0.1433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1026">
         <PDBx:U11>0.1209</PDBx:U11>
         <PDBx:U12>0.0177</PDBx:U12>
         <PDBx:U13>-0.0095</PDBx:U13>
         <PDBx:U22>0.1532</PDBx:U22>
         <PDBx:U23>-0.0313</PDBx:U23>
         <PDBx:U33>0.0565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1027">
         <PDBx:U11>0.0822</PDBx:U11>
         <PDBx:U12>0.0150</PDBx:U12>
         <PDBx:U13>-0.0051</PDBx:U13>
         <PDBx:U22>0.1105</PDBx:U22>
         <PDBx:U23>-0.0157</PDBx:U23>
         <PDBx:U33>0.0539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1028">
         <PDBx:U11>0.1405</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.1698</PDBx:U22>
         <PDBx:U23>-0.0328</PDBx:U23>
         <PDBx:U33>0.0600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1029">
         <PDBx:U11>0.1480</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1790</PDBx:U22>
         <PDBx:U23>-0.0378</PDBx:U23>
         <PDBx:U33>0.0687</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1030">
         <PDBx:U11>0.0864</PDBx:U11>
         <PDBx:U12>0.0182</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.1033</PDBx:U22>
         <PDBx:U23>-0.0122</PDBx:U23>
         <PDBx:U33>0.0541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1031">
         <PDBx:U11>0.1826</PDBx:U11>
         <PDBx:U12>0.0145</PDBx:U12>
         <PDBx:U13>-0.0093</PDBx:U13>
         <PDBx:U22>0.1912</PDBx:U22>
         <PDBx:U23>-0.0233</PDBx:U23>
         <PDBx:U33>0.0669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1032">
         <PDBx:U11>0.1202</PDBx:U11>
         <PDBx:U12>0.0177</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.1215</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.0480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1033">
         <PDBx:U11>0.1408</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0083</PDBx:U13>
         <PDBx:U22>0.1392</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.0412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1034">
         <PDBx:U11>0.1282</PDBx:U11>
         <PDBx:U12>0.0142</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.1324</PDBx:U22>
         <PDBx:U23>-0.0169</PDBx:U23>
         <PDBx:U33>0.0419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1035">
         <PDBx:U11>0.0947</PDBx:U11>
         <PDBx:U12>0.0066</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1269</PDBx:U22>
         <PDBx:U23>-0.0217</PDBx:U23>
         <PDBx:U33>0.0480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1036">
         <PDBx:U11>0.0937</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1295</PDBx:U22>
         <PDBx:U23>-0.0234</PDBx:U23>
         <PDBx:U33>0.0505</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1037">
         <PDBx:U11>0.1208</PDBx:U11>
         <PDBx:U12>0.0053</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1477</PDBx:U22>
         <PDBx:U23>-0.0261</PDBx:U23>
         <PDBx:U33>0.0516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1038">
         <PDBx:U11>0.0872</PDBx:U11>
         <PDBx:U12>0.0068</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1077</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.0473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1039">
         <PDBx:U11>0.1136</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1478</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.0550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1040">
         <PDBx:U11>0.1721</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1967</PDBx:U22>
         <PDBx:U23>-0.0297</PDBx:U23>
         <PDBx:U33>0.0627</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1041">
         <PDBx:U11>0.1261</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.1536</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.0543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1042">
         <PDBx:U11>0.0841</PDBx:U11>
         <PDBx:U12>0.0044</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.1164</PDBx:U22>
         <PDBx:U23>-0.0219</PDBx:U23>
         <PDBx:U33>0.0445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1043">
         <PDBx:U11>0.0957</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1216</PDBx:U22>
         <PDBx:U23>-0.0213</PDBx:U23>
         <PDBx:U33>0.0464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1044">
         <PDBx:U11>0.1253</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.1448</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.0460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1045">
         <PDBx:U11>0.0993</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1226</PDBx:U22>
         <PDBx:U23>-0.0187</PDBx:U23>
         <PDBx:U33>0.0433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1046">
         <PDBx:U11>0.1182</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1487</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.0546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1047">
         <PDBx:U11>0.1150</PDBx:U11>
         <PDBx:U12>0.0025</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1276</PDBx:U22>
         <PDBx:U23>-0.0159</PDBx:U23>
         <PDBx:U33>0.0458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1048">
         <PDBx:U11>0.1193</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.1269</PDBx:U22>
         <PDBx:U23>-0.0117</PDBx:U23>
         <PDBx:U33>0.0508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1049">
         <PDBx:U11>0.1303</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.1344</PDBx:U22>
         <PDBx:U23>-0.0128</PDBx:U23>
         <PDBx:U33>0.0454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1050">
         <PDBx:U11>0.1054</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.1078</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1051">
         <PDBx:U11>0.1700</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1719</PDBx:U22>
         <PDBx:U23>-0.0130</PDBx:U23>
         <PDBx:U33>0.0603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1052">
         <PDBx:U11>0.1775</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.1824</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.0624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1053">
         <PDBx:U11>0.1952</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1927</PDBx:U22>
         <PDBx:U23>-0.0108</PDBx:U23>
         <PDBx:U33>0.0625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1054">
         <PDBx:U11>0.2390</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.1066</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1055">
         <PDBx:U11>0.0557</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.0599</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1056">
         <PDBx:U11>0.0557</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.0567</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1057">
         <PDBx:U11>0.1024</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0975</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.0442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.0673</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0614</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1059">
         <PDBx:U11>0.0653</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.0698</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1060">
         <PDBx:U11>0.0904</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.0820</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1061">
         <PDBx:U11>0.0622</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.0498</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1062">
         <PDBx:U11>0.0635</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0500</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1063">
         <PDBx:U11>0.0572</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0416</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1064">
         <PDBx:U11>0.0811</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.0661</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.0425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1065">
         <PDBx:U11>0.1255</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1079</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1066">
         <PDBx:U11>0.1574</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.1392</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1067">
         <PDBx:U11>0.1577</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1383</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.0475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1068">
         <PDBx:U11>0.1489</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1293</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1069">
         <PDBx:U11>0.1530</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1328</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.0473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1070">
         <PDBx:U11>0.0827</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.0704</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1071">
         <PDBx:U11>0.0858</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.0721</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.0450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1072">
         <PDBx:U11>0.1591</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.1425</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1073">
         <PDBx:U11>0.1966</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.1787</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1074">
         <PDBx:U11>0.0641</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.0490</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1075">
         <PDBx:U11>0.0665</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.0555</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1076">
         <PDBx:U11>0.1827</PDBx:U11>
         <PDBx:U12>-0.0197</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.1692</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.0824</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1077">
         <PDBx:U11>0.2693</PDBx:U11>
         <PDBx:U12>-0.0197</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.2523</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.0978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1078">
         <PDBx:U11>0.3361</PDBx:U11>
         <PDBx:U12>-0.0234</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.3141</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.1526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1079">
         <PDBx:U11>0.3540</PDBx:U11>
         <PDBx:U12>-0.0276</PDBx:U12>
         <PDBx:U13>0.0144</PDBx:U13>
         <PDBx:U22>0.3299</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.1645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1080">
         <PDBx:U11>0.1827</PDBx:U11>
         <PDBx:U12>-0.0232</PDBx:U12>
         <PDBx:U13>0.0094</PDBx:U13>
         <PDBx:U22>0.1570</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.0423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1081">
         <PDBx:U11>0.1039</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.0862</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1082">
         <PDBx:U11>0.1181</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.0990</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1083">
         <PDBx:U11>0.1331</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1144</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1084">
         <PDBx:U11>0.1174</PDBx:U11>
         <PDBx:U12>-0.0011</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.0980</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.0475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1085">
         <PDBx:U11>0.1611</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1396</PDBx:U22>
         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.0542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1086">
         <PDBx:U11>0.2810</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.2588</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.1149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1087">
         <PDBx:U11>0.2967</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.2754</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.1312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1088">
         <PDBx:U11>0.2813</PDBx:U11>
         <PDBx:U12>-0.0010</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.2580</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.1146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1089">
         <PDBx:U11>0.1121</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.0941</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.0522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1090">
         <PDBx:U11>0.1202</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1009</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1091">
         <PDBx:U11>0.1539</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.1347</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1092">
         <PDBx:U11>0.1708</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.1529</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1093">
         <PDBx:U11>0.1343</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1147</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.0551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1094">
         <PDBx:U11>0.2209</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1979</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1095">
         <PDBx:U11>0.2276</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.2027</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.0776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1096">
         <PDBx:U11>0.2522</PDBx:U11>
         <PDBx:U12>0.0022</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.2286</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0016</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1843</PDBx:U11>
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         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.0540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0004</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.0744</PDBx:U11>
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         <PDBx:U13>0.0024</PDBx:U13>
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         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0059</PDBx:U13>
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         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1113">
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         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.0871</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1114">
         <PDBx:U11>0.1619</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1465</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1115">
         <PDBx:U11>0.1895</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1754</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1116">
         <PDBx:U11>0.1469</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1369</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1117">
         <PDBx:U11>0.1551</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1494</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.0695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1118">
         <PDBx:U11>0.2902</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.2859</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.1396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1119">
         <PDBx:U11>0.5316</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.5325</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.3842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1120">
         <PDBx:U11>0.7090</PDBx:U11>
         <PDBx:U12>0.0020</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.7106</PDBx:U22>
         <PDBx:U23>-0.0196</PDBx:U23>
         <PDBx:U33>0.5623</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1121">
         <PDBx:U11>0.1164</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.0981</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1122">
         <PDBx:U11>0.1272</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1074</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1123">
         <PDBx:U11>0.1495</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1267</PDBx:U22>
         <PDBx:U23>0.0011</PDBx:U23>
         <PDBx:U33>0.0514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1124">
         <PDBx:U11>0.1607</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1370</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.0539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1125">
         <PDBx:U11>0.1425</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.1226</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.0669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1126">
         <PDBx:U11>0.2472</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.2282</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1127">
         <PDBx:U11>0.2480</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.2301</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1128">
         <PDBx:U11>0.2351</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.2153</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.0749</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1129">
         <PDBx:U11>0.0673</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0426</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1130">
         <PDBx:U11>0.0651</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.0388</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1131">
         <PDBx:U11>0.1255</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.0961</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1132">
         <PDBx:U11>0.1213</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.0942</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1133">
         <PDBx:U11>0.1167</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.0837</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1134">
         <PDBx:U11>0.1109</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0791</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1135">
         <PDBx:U11>0.1144</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.0750</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.0404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1136">
         <PDBx:U11>0.1129</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.0786</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1137">
         <PDBx:U11>0.0812</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0493</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1138">
         <PDBx:U11>0.0744</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.0426</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1139">
         <PDBx:U11>0.1425</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1030</PDBx:U22>
         <PDBx:U23>0.0015</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1140">
         <PDBx:U11>0.1518</PDBx:U11>
         <PDBx:U12>-0.0142</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1074</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1141">
         <PDBx:U11>0.0722</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0427</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1142">
         <PDBx:U11>0.1232</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.0985</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1143">
         <PDBx:U11>0.1329</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1089</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1144">
         <PDBx:U11>0.2262</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.2068</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.0610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1145">
         <PDBx:U11>0.0889</PDBx:U11>
         <PDBx:U12>-0.0206</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.0483</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1146">
         <PDBx:U11>0.1061</PDBx:U11>
         <PDBx:U12>-0.0248</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0574</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1147">
         <PDBx:U11>0.1717</PDBx:U11>
         <PDBx:U12>-0.0283</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1214</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1148">
         <PDBx:U11>0.1600</PDBx:U11>
         <PDBx:U12>-0.0306</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.1159</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1149">
         <PDBx:U11>0.1679</PDBx:U11>
         <PDBx:U12>-0.0290</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.1194</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1150">
         <PDBx:U11>0.1674</PDBx:U11>
         <PDBx:U12>-0.0345</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1089</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1151">
         <PDBx:U11>0.1643</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.1179</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1152">
         <PDBx:U11>0.1553</PDBx:U11>
         <PDBx:U12>-0.0285</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.0968</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1153">
         <PDBx:U11>0.1521</PDBx:U11>
         <PDBx:U12>-0.0320</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.0902</PDBx:U22>
         <PDBx:U23>0.0027</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1154">
         <PDBx:U11>0.2526</PDBx:U11>
         <PDBx:U12>-0.0396</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1845</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.0462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1155">
         <PDBx:U11>0.2600</PDBx:U11>
         <PDBx:U12>-0.0414</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.1889</PDBx:U22>
         <PDBx:U23>0.0072</PDBx:U23>
         <PDBx:U33>0.0524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1156">
         <PDBx:U11>0.1767</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1080</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1157">
         <PDBx:U11>0.2538</PDBx:U11>
         <PDBx:U12>-0.0222</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1904</PDBx:U22>
         <PDBx:U23>0.0108</PDBx:U23>
         <PDBx:U33>0.0799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1158">
         <PDBx:U11>0.3440</PDBx:U11>
         <PDBx:U12>-0.0195</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.2748</PDBx:U22>
         <PDBx:U23>0.0164</PDBx:U23>
         <PDBx:U33>0.1377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1159">
         <PDBx:U11>0.3075</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.2455</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.1099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1160">
         <PDBx:U11>0.2958</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>-0.0106</PDBx:U13>
         <PDBx:U22>0.2300</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.0962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1161">
         <PDBx:U11>0.2271</PDBx:U11>
         <PDBx:U12>-0.0442</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1574</PDBx:U22>
         <PDBx:U23>0.0061</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1162">
         <PDBx:U11>0.2114</PDBx:U11>
         <PDBx:U12>-0.0526</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1355</PDBx:U22>
         <PDBx:U23>0.0039</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1163">
         <PDBx:U11>0.3038</PDBx:U11>
         <PDBx:U12>-0.0546</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.2137</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.0643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1164">
         <PDBx:U11>0.3259</PDBx:U11>
         <PDBx:U12>-0.0609</PDBx:U12>
         <PDBx:U13>0.0079</PDBx:U13>
         <PDBx:U22>0.2316</PDBx:U22>
         <PDBx:U23>0.0105</PDBx:U23>
         <PDBx:U33>0.0693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1165">
         <PDBx:U11>0.2299</PDBx:U11>
         <PDBx:U12>-0.0565</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.1538</PDBx:U22>
         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1166">
         <PDBx:U11>0.3638</PDBx:U11>
         <PDBx:U12>-0.0669</PDBx:U12>
         <PDBx:U13>0.0121</PDBx:U13>
         <PDBx:U22>0.2840</PDBx:U22>
         <PDBx:U23>0.0066</PDBx:U23>
         <PDBx:U33>0.1093</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1167">
         <PDBx:U11>0.4347</PDBx:U11>
         <PDBx:U12>-0.0707</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.3586</PDBx:U22>
         <PDBx:U23>0.0054</PDBx:U23>
         <PDBx:U33>0.1785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1168">
         <PDBx:U11>0.5332</PDBx:U11>
         <PDBx:U12>-0.0818</PDBx:U12>
         <PDBx:U13>0.0165</PDBx:U13>
         <PDBx:U22>0.4526</PDBx:U22>
         <PDBx:U23>0.0033</PDBx:U23>
         <PDBx:U33>0.2644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1169">
         <PDBx:U11>0.4964</PDBx:U11>
         <PDBx:U12>-0.0856</PDBx:U12>
         <PDBx:U13>0.0199</PDBx:U13>
         <PDBx:U22>0.4253</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.2306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1170">
         <PDBx:U11>0.2641</PDBx:U11>
         <PDBx:U12>-0.0492</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1671</PDBx:U22>
         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.0574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1171">
         <PDBx:U11>0.3049</PDBx:U11>
         <PDBx:U12>-0.0502</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.1930</PDBx:U22>
         <PDBx:U23>0.0171</PDBx:U23>
         <PDBx:U33>0.0614</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1172">
         <PDBx:U11>0.3051</PDBx:U11>
         <PDBx:U12>-0.0477</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1929</PDBx:U22>
         <PDBx:U23>0.0168</PDBx:U23>
         <PDBx:U33>0.0607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1173">
         <PDBx:U11>0.3324</PDBx:U11>
         <PDBx:U12>-0.0478</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.2079</PDBx:U22>
         <PDBx:U23>0.0206</PDBx:U23>
         <PDBx:U33>0.0692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1174">
         <PDBx:U11>0.3505</PDBx:U11>
         <PDBx:U12>-0.0452</PDBx:U12>
         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.2310</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.0891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0227</PDBx:U23>
         <PDBx:U33>0.2076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2266</PDBx:U11>
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         <PDBx:U23>0.0128</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1177">
         <PDBx:U11>0.4630</PDBx:U11>
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         <PDBx:U22>0.3472</PDBx:U22>
         <PDBx:U23>0.0249</PDBx:U23>
         <PDBx:U33>0.2160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2616</PDBx:U11>
         <PDBx:U12>-0.0454</PDBx:U12>
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         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.0503</PDBx:U33>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0096</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2686</PDBx:U11>
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         <PDBx:U23>0.0137</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0110</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2303</PDBx:U11>
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         <PDBx:U23>0.0102</PDBx:U23>
         <PDBx:U33>0.0519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0056</PDBx:U13>
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         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0124</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0098</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2896</PDBx:U11>
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         <PDBx:U23>0.0185</PDBx:U23>
         <PDBx:U33>0.0700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1187">
         <PDBx:U11>0.2617</PDBx:U11>
         <PDBx:U12>-0.0205</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.1688</PDBx:U22>
         <PDBx:U23>0.0174</PDBx:U23>
         <PDBx:U33>0.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3197</PDBx:U11>
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         <PDBx:U22>0.2069</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.0878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1189">
         <PDBx:U11>0.2150</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
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         <PDBx:U22>0.1426</PDBx:U22>
         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.0573</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2149</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1530</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.0600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2380</PDBx:U11>
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         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>0.0105</PDBx:U23>
         <PDBx:U33>0.0650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0074</PDBx:U13>
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         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.0712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0082</PDBx:U23>
         <PDBx:U33>0.0598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2964</PDBx:U11>
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         <PDBx:U33>0.1082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U11>0.2127</PDBx:U11>
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         <PDBx:U23>0.0077</PDBx:U23>
         <PDBx:U33>0.0666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1196">
         <PDBx:U11>0.2224</PDBx:U11>
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         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1759</PDBx:U22>
         <PDBx:U23>0.0085</PDBx:U23>
         <PDBx:U33>0.0704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1732</PDBx:U11>
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         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1336</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.0503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1198">
         <PDBx:U11>0.1673</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.1303</PDBx:U22>
         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.0403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1199">
         <PDBx:U11>0.2517</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.2053</PDBx:U22>
         <PDBx:U23>0.0114</PDBx:U23>
         <PDBx:U33>0.0740</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1200">
         <PDBx:U11>0.3126</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.2717</PDBx:U22>
         <PDBx:U23>0.0102</PDBx:U23>
         <PDBx:U33>0.1348</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1201">
         <PDBx:U11>0.0951</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.0583</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1202">
         <PDBx:U11>0.0653</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.0380</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1203">
         <PDBx:U11>0.1056</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.0772</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1204">
         <PDBx:U11>0.1094</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0811</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1205">
         <PDBx:U11>0.0964</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.0658</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.0478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1206">
         <PDBx:U11>0.1092</PDBx:U11>
         <PDBx:U12>0.0027</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.0748</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.0521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1207">
         <PDBx:U11>0.1485</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1226</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.0515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1208">
         <PDBx:U11>0.2986</PDBx:U11>
         <PDBx:U12>0.0051</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.2647</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.1451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1209">
         <PDBx:U11>0.1012</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.0754</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.0440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1210">
         <PDBx:U11>0.1205</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0971</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.0476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1211">
         <PDBx:U11>0.1880</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.1662</PDBx:U22>
         <PDBx:U23>0.0035</PDBx:U23>
         <PDBx:U33>0.0654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1212">
         <PDBx:U11>0.1688</PDBx:U11>
         <PDBx:U12>0.0004</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.1469</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1213">
         <PDBx:U11>0.1431</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.1202</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.0501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1214">
         <PDBx:U11>0.1581</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1373</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.0622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1215">
         <PDBx:U11>0.1865</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.1656</PDBx:U22>
         <PDBx:U23>0.0030</PDBx:U23>
         <PDBx:U33>0.0671</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1216">
         <PDBx:U11>0.2204</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1993</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.0660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1217">
         <PDBx:U11>0.2286</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.2075</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.0672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1218">
         <PDBx:U11>0.2360</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.2154</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.0753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1219">
         <PDBx:U11>0.4754</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.4561</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.3155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1220">
         <PDBx:U11>0.5049</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.4865</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.3457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1221">
         <PDBx:U11>0.6243</PDBx:U11>
         <PDBx:U12>0.0020</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.6051</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.4644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1222">
         <PDBx:U11>0.1520</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1315</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.0581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1223">
         <PDBx:U11>0.1413</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.1218</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.0583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1224">
         <PDBx:U11>0.1639</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1435</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.0466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1225">
         <PDBx:U11>0.1572</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.1382</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.0401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1226">
         <PDBx:U11>0.1463</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1281</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.0634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1227">
         <PDBx:U11>0.2102</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.1913</PDBx:U22>
         <PDBx:U23>0.0029</PDBx:U23>
         <PDBx:U33>0.0846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1228">
         <PDBx:U11>0.2319</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.2139</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.0862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1229">
         <PDBx:U11>0.2424</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.2234</PDBx:U22>
         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.0885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1230">
         <PDBx:U11>0.1183</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.0953</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1231">
         <PDBx:U11>0.1144</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0883</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1232">
         <PDBx:U11>0.1919</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1648</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.0577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1233">
         <PDBx:U11>0.1950</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1657</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.0566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1234">
         <PDBx:U11>0.1333</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1077</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.0559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1235">
         <PDBx:U11>0.1462</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1201</PDBx:U22>
         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.0622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1236">
         <PDBx:U11>0.1707</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1494</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.0569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1237">
         <PDBx:U11>0.1638</PDBx:U11>
         <PDBx:U12>-0.0131</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1436</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1238">
         <PDBx:U11>0.1589</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.0654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1239">
         <PDBx:U11>0.2401</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.2082</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.0777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1240">
         <PDBx:U11>0.2376</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.2060</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.0753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1241">
         <PDBx:U11>0.2677</PDBx:U11>
         <PDBx:U12>-0.0111</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.2302</PDBx:U22>
         <PDBx:U23>0.0035</PDBx:U23>
         <PDBx:U33>0.0870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1242">
         <PDBx:U11>0.0860</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0677</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1243">
         <PDBx:U11>0.0872</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.0738</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.0445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1244">
         <PDBx:U11>0.1592</PDBx:U11>
         <PDBx:U12>-0.0127</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.1481</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1245">
         <PDBx:U11>0.1569</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.1429</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.0492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1246">
         <PDBx:U11>0.0681</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.0563</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1247">
         <PDBx:U11>0.0931</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.0872</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.0500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1248">
         <PDBx:U11>0.0919</PDBx:U11>
         <PDBx:U12>-0.0182</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.0902</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1249">
         <PDBx:U11>0.1609</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.1658</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.0618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1250">
         <PDBx:U11>0.1768</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.1823</PDBx:U22>
         <PDBx:U23>-0.0165</PDBx:U23>
         <PDBx:U33>0.0607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1251">
         <PDBx:U11>0.1593</PDBx:U11>
         <PDBx:U12>-0.0218</PDBx:U12>
         <PDBx:U13>0.0130</PDBx:U13>
         <PDBx:U22>0.1590</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.0535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1252">
         <PDBx:U11>0.1647</PDBx:U11>
         <PDBx:U12>-0.0252</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.1574</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.0494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1253">
         <PDBx:U11>0.1639</PDBx:U11>
         <PDBx:U12>-0.0188</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.1662</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.0560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1254">
         <PDBx:U11>0.1131</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.1224</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.0543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1255">
         <PDBx:U11>0.1264</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.0097</PDBx:U13>
         <PDBx:U22>0.1425</PDBx:U22>
         <PDBx:U23>-0.0162</PDBx:U23>
         <PDBx:U33>0.0569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1256">
         <PDBx:U11>0.1777</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>0.2008</PDBx:U22>
         <PDBx:U23>-0.0301</PDBx:U23>
         <PDBx:U33>0.0669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1257">
         <PDBx:U11>0.1945</PDBx:U11>
         <PDBx:U12>-0.0245</PDBx:U12>
         <PDBx:U13>0.0205</PDBx:U13>
         <PDBx:U22>0.2173</PDBx:U22>
         <PDBx:U23>-0.0329</PDBx:U23>
         <PDBx:U33>0.0717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1258">
         <PDBx:U11>0.1566</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1716</PDBx:U22>
         <PDBx:U23>-0.0185</PDBx:U23>
         <PDBx:U33>0.0642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1259">
         <PDBx:U11>0.1030</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1109</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.0594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1260">
         <PDBx:U11>0.1487</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.1560</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.0627</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1261">
         <PDBx:U11>0.0971</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1043</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.0463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1262">
         <PDBx:U11>0.2175</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0145</PDBx:U13>
         <PDBx:U22>0.2237</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.0661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1263">
         <PDBx:U11>0.2305</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.2364</PDBx:U22>
         <PDBx:U23>-0.0153</PDBx:U23>
         <PDBx:U33>0.0822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1264">
         <PDBx:U11>0.1772</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0128</PDBx:U13>
         <PDBx:U22>0.1825</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.0630</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1265">
         <PDBx:U11>0.1151</PDBx:U11>
         <PDBx:U12>-0.0165</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.1463</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.0565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1266">
         <PDBx:U11>0.1327</PDBx:U11>
         <PDBx:U12>-0.0188</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.1727</PDBx:U22>
         <PDBx:U23>-0.0359</PDBx:U23>
         <PDBx:U33>0.0592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1267">
         <PDBx:U11>0.2084</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>0.0208</PDBx:U13>
         <PDBx:U22>0.2528</PDBx:U22>
         <PDBx:U23>-0.0536</PDBx:U23>
         <PDBx:U33>0.0955</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1268">
         <PDBx:U11>0.1785</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0172</PDBx:U13>
         <PDBx:U22>0.2229</PDBx:U22>
         <PDBx:U23>-0.0521</PDBx:U23>
         <PDBx:U33>0.0710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1269">
         <PDBx:U11>0.1484</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.1902</PDBx:U22>
         <PDBx:U23>-0.0433</PDBx:U23>
         <PDBx:U33>0.0644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1270">
         <PDBx:U11>0.2007</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.0203</PDBx:U13>
         <PDBx:U22>0.2496</PDBx:U22>
         <PDBx:U23>-0.0598</PDBx:U23>
         <PDBx:U33>0.0986</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1271">
         <PDBx:U11>0.2269</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.2812</PDBx:U22>
         <PDBx:U23>-0.0656</PDBx:U23>
         <PDBx:U33>0.1365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1272">
         <PDBx:U11>0.2351</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0252</PDBx:U13>
         <PDBx:U22>0.2879</PDBx:U22>
         <PDBx:U23>-0.0640</PDBx:U23>
         <PDBx:U33>0.1299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1273">
         <PDBx:U11>0.2222</PDBx:U11>
         <PDBx:U12>-0.0149</PDBx:U12>
         <PDBx:U13>0.0209</PDBx:U13>
         <PDBx:U22>0.2849</PDBx:U22>
         <PDBx:U23>-0.0736</PDBx:U23>
         <PDBx:U33>0.1367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1274">
         <PDBx:U11>0.2293</PDBx:U11>
         <PDBx:U12>-0.0225</PDBx:U12>
         <PDBx:U13>0.0258</PDBx:U13>
         <PDBx:U22>0.2913</PDBx:U22>
         <PDBx:U23>-0.0728</PDBx:U23>
         <PDBx:U33>0.1347</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1275">
         <PDBx:U11>0.2176</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>0.0251</PDBx:U13>
         <PDBx:U22>0.2686</PDBx:U22>
         <PDBx:U23>-0.0601</PDBx:U23>
         <PDBx:U33>0.1048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1276">
         <PDBx:U11>0.2356</PDBx:U11>
         <PDBx:U12>-0.0247</PDBx:U12>
         <PDBx:U13>0.0260</PDBx:U13>
         <PDBx:U22>0.2957</PDBx:U22>
         <PDBx:U23>-0.0674</PDBx:U23>
         <PDBx:U33>0.1298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1277">
         <PDBx:U11>0.2693</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>0.0263</PDBx:U13>
         <PDBx:U22>0.3389</PDBx:U22>
         <PDBx:U23>-0.0765</PDBx:U23>
         <PDBx:U33>0.1748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1278">
         <PDBx:U11>0.2524</PDBx:U11>
         <PDBx:U12>-0.0301</PDBx:U12>
         <PDBx:U13>0.0306</PDBx:U13>
         <PDBx:U22>0.3260</PDBx:U22>
         <PDBx:U23>-0.0812</PDBx:U23>
         <PDBx:U33>0.1566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1279">
         <PDBx:U11>0.2948</PDBx:U11>
         <PDBx:U12>-0.0329</PDBx:U12>
         <PDBx:U13>0.0310</PDBx:U13>
         <PDBx:U22>0.3559</PDBx:U22>
         <PDBx:U23>-0.0693</PDBx:U23>
         <PDBx:U33>0.1809</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1280">
         <PDBx:U11>0.5163</PDBx:U11>
         <PDBx:U12>-0.0339</PDBx:U12>
         <PDBx:U13>0.0322</PDBx:U13>
         <PDBx:U22>0.5878</PDBx:U22>
         <PDBx:U23>-0.0776</PDBx:U23>
         <PDBx:U33>0.4102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1281">
         <PDBx:U11>0.5194</PDBx:U11>
         <PDBx:U12>-0.0286</PDBx:U12>
         <PDBx:U13>0.0288</PDBx:U13>
         <PDBx:U22>0.5914</PDBx:U22>
         <PDBx:U23>-0.0762</PDBx:U23>
         <PDBx:U33>0.4175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1282">
         <PDBx:U11>0.6575</PDBx:U11>
         <PDBx:U12>-0.0401</PDBx:U12>
         <PDBx:U13>0.0366</PDBx:U13>
         <PDBx:U22>0.7372</PDBx:U22>
         <PDBx:U23>-0.0859</PDBx:U23>
         <PDBx:U33>0.5535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1283">
         <PDBx:U11>0.2295</PDBx:U11>
         <PDBx:U12>-0.0163</PDBx:U12>
         <PDBx:U13>0.0212</PDBx:U13>
         <PDBx:U22>0.3015</PDBx:U22>
         <PDBx:U23>-0.0785</PDBx:U23>
         <PDBx:U33>0.1456</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1284">
         <PDBx:U11>0.2146</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.2947</PDBx:U22>
         <PDBx:U23>-0.0869</PDBx:U23>
         <PDBx:U33>0.1426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1285">
         <PDBx:U11>0.2443</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0240</PDBx:U13>
         <PDBx:U22>0.3378</PDBx:U22>
         <PDBx:U23>-0.0988</PDBx:U23>
         <PDBx:U33>0.1803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1286">
         <PDBx:U11>0.2324</PDBx:U11>
         <PDBx:U12>-0.0197</PDBx:U12>
         <PDBx:U13>0.0253</PDBx:U13>
         <PDBx:U22>0.3324</PDBx:U22>
         <PDBx:U23>-0.1059</PDBx:U23>
         <PDBx:U33>0.1755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1287">
         <PDBx:U11>0.2617</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.3401</PDBx:U22>
         <PDBx:U23>-0.0865</PDBx:U23>
         <PDBx:U33>0.1983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1288">
         <PDBx:U11>0.3975</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.4816</PDBx:U22>
         <PDBx:U23>-0.0909</PDBx:U23>
         <PDBx:U33>0.3407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1289">
         <PDBx:U11>0.2170</PDBx:U11>
         <PDBx:U12>-0.0215</PDBx:U12>
         <PDBx:U13>0.0259</PDBx:U13>
         <PDBx:U22>0.3150</PDBx:U22>
         <PDBx:U23>-0.1017</PDBx:U23>
         <PDBx:U33>0.1523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1290">
         <PDBx:U11>0.2052</PDBx:U11>
         <PDBx:U12>-0.0264</PDBx:U12>
         <PDBx:U13>0.0299</PDBx:U13>
         <PDBx:U22>0.3170</PDBx:U22>
         <PDBx:U23>-0.1141</PDBx:U23>
         <PDBx:U33>0.1485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1291">
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         <PDBx:U13>0.0369</PDBx:U13>
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         <PDBx:U23>-0.1176</PDBx:U23>
         <PDBx:U33>0.2115</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1292">
         <PDBx:U11>0.2411</PDBx:U11>
         <PDBx:U12>-0.0398</PDBx:U12>
         <PDBx:U13>0.0398</PDBx:U13>
         <PDBx:U22>0.3671</PDBx:U22>
         <PDBx:U23>-0.1287</PDBx:U23>
         <PDBx:U33>0.1869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1293">
         <PDBx:U11>0.2109</PDBx:U11>
         <PDBx:U12>-0.0277</PDBx:U12>
         <PDBx:U13>0.0306</PDBx:U13>
         <PDBx:U22>0.3260</PDBx:U22>
         <PDBx:U23>-0.1156</PDBx:U23>
         <PDBx:U33>0.1535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1294">
         <PDBx:U11>0.2629</PDBx:U11>
         <PDBx:U12>-0.0418</PDBx:U12>
         <PDBx:U13>0.0396</PDBx:U13>
         <PDBx:U22>0.3666</PDBx:U22>
         <PDBx:U23>-0.1087</PDBx:U23>
         <PDBx:U33>0.1842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1295">
         <PDBx:U11>0.2815</PDBx:U11>
         <PDBx:U12>-0.0520</PDBx:U12>
         <PDBx:U13>0.0458</PDBx:U13>
         <PDBx:U22>0.3850</PDBx:U22>
         <PDBx:U23>-0.1106</PDBx:U23>
         <PDBx:U33>0.1935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1296">
         <PDBx:U11>0.3360</PDBx:U11>
         <PDBx:U12>-0.0513</PDBx:U12>
         <PDBx:U13>0.0451</PDBx:U13>
         <PDBx:U22>0.4325</PDBx:U22>
         <PDBx:U23>-0.1054</PDBx:U23>
         <PDBx:U33>0.2437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1297">
         <PDBx:U11>0.3391</PDBx:U11>
         <PDBx:U12>-0.0592</PDBx:U12>
         <PDBx:U13>0.0497</PDBx:U13>
         <PDBx:U22>0.4364</PDBx:U22>
         <PDBx:U23>-0.1081</PDBx:U23>
         <PDBx:U33>0.2410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1298">
         <PDBx:U11>0.4389</PDBx:U11>
         <PDBx:U12>-0.0589</PDBx:U12>
         <PDBx:U13>0.0490</PDBx:U13>
         <PDBx:U22>0.5343</PDBx:U22>
         <PDBx:U23>-0.1048</PDBx:U23>
         <PDBx:U33>0.3353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1299">
         <PDBx:U11>0.4484</PDBx:U11>
         <PDBx:U12>-0.0535</PDBx:U12>
         <PDBx:U13>0.0448</PDBx:U13>
         <PDBx:U22>0.5309</PDBx:U22>
         <PDBx:U23>-0.0928</PDBx:U23>
         <PDBx:U33>0.3371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1300">
         <PDBx:U11>0.3970</PDBx:U11>
         <PDBx:U12>-0.0619</PDBx:U12>
         <PDBx:U13>0.0513</PDBx:U13>
         <PDBx:U22>0.5002</PDBx:U22>
         <PDBx:U23>-0.1113</PDBx:U23>
         <PDBx:U33>0.2963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1301">
         <PDBx:U11>0.2685</PDBx:U11>
         <PDBx:U12>-0.0426</PDBx:U12>
         <PDBx:U13>0.0395</PDBx:U13>
         <PDBx:U22>0.3581</PDBx:U22>
         <PDBx:U23>-0.0981</PDBx:U23>
         <PDBx:U33>0.1785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1302">
         <PDBx:U11>0.2560</PDBx:U11>
         <PDBx:U12>-0.0409</PDBx:U12>
         <PDBx:U13>0.0382</PDBx:U13>
         <PDBx:U22>0.3382</PDBx:U22>
         <PDBx:U23>-0.0922</PDBx:U23>
         <PDBx:U33>0.1621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1303">
         <PDBx:U11>0.3062</PDBx:U11>
         <PDBx:U12>-0.0473</PDBx:U12>
         <PDBx:U13>0.0409</PDBx:U13>
         <PDBx:U22>0.3780</PDBx:U22>
         <PDBx:U23>-0.0844</PDBx:U23>
         <PDBx:U33>0.1954</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1304">
         <PDBx:U11>0.3266</PDBx:U11>
         <PDBx:U12>-0.0527</PDBx:U12>
         <PDBx:U13>0.0437</PDBx:U13>
         <PDBx:U22>0.3971</PDBx:U22>
         <PDBx:U23>-0.0850</PDBx:U23>
         <PDBx:U33>0.2103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1305">
         <PDBx:U11>0.2782</PDBx:U11>
         <PDBx:U12>-0.0418</PDBx:U12>
         <PDBx:U13>0.0397</PDBx:U13>
         <PDBx:U22>0.3691</PDBx:U22>
         <PDBx:U23>-0.1008</PDBx:U23>
         <PDBx:U33>0.1938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1306">
         <PDBx:U11>0.4477</PDBx:U11>
         <PDBx:U12>-0.0374</PDBx:U12>
         <PDBx:U13>0.0370</PDBx:U13>
         <PDBx:U22>0.5330</PDBx:U22>
         <PDBx:U23>-0.0962</PDBx:U23>
         <PDBx:U33>0.3641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1307">
         <PDBx:U11>0.4321</PDBx:U11>
         <PDBx:U12>-0.0316</PDBx:U12>
         <PDBx:U13>0.0329</PDBx:U13>
         <PDBx:U22>0.5077</PDBx:U22>
         <PDBx:U23>-0.0871</PDBx:U23>
         <PDBx:U33>0.3445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1308">
         <PDBx:U11>0.5190</PDBx:U11>
         <PDBx:U12>-0.0396</PDBx:U12>
         <PDBx:U13>0.0390</PDBx:U13>
         <PDBx:U22>0.6102</PDBx:U22>
         <PDBx:U23>-0.1025</PDBx:U23>
         <PDBx:U33>0.4408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1309">
         <PDBx:U11>0.2399</PDBx:U11>
         <PDBx:U12>-0.0468</PDBx:U12>
         <PDBx:U13>0.0397</PDBx:U13>
         <PDBx:U22>0.3045</PDBx:U22>
         <PDBx:U23>-0.0778</PDBx:U23>
         <PDBx:U33>0.1210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1310">
         <PDBx:U11>0.2200</PDBx:U11>
         <PDBx:U12>-0.0516</PDBx:U12>
         <PDBx:U13>0.0409</PDBx:U13>
         <PDBx:U22>0.2734</PDBx:U22>
         <PDBx:U23>-0.0700</PDBx:U23>
         <PDBx:U33>0.0853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1311">
         <PDBx:U11>0.2550</PDBx:U11>
         <PDBx:U12>-0.0446</PDBx:U12>
         <PDBx:U13>0.0361</PDBx:U13>
         <PDBx:U22>0.2988</PDBx:U22>
         <PDBx:U23>-0.0602</PDBx:U23>
         <PDBx:U33>0.1170</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1312">
         <PDBx:U11>0.2872</PDBx:U11>
         <PDBx:U12>-0.0383</PDBx:U12>
         <PDBx:U13>0.0330</PDBx:U13>
         <PDBx:U22>0.3327</PDBx:U22>
         <PDBx:U23>-0.0595</PDBx:U23>
         <PDBx:U33>0.1563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1313">
         <PDBx:U11>0.3507</PDBx:U11>
         <PDBx:U12>-0.0589</PDBx:U12>
         <PDBx:U13>0.0445</PDBx:U13>
         <PDBx:U22>0.4045</PDBx:U22>
         <PDBx:U23>-0.0723</PDBx:U23>
         <PDBx:U33>0.2084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1314">
         <PDBx:U11>0.3513</PDBx:U11>
         <PDBx:U12>-0.0542</PDBx:U12>
         <PDBx:U13>0.0425</PDBx:U13>
         <PDBx:U22>0.4084</PDBx:U22>
         <PDBx:U23>-0.0729</PDBx:U23>
         <PDBx:U33>0.2154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1315">
         <PDBx:U11>0.3599</PDBx:U11>
         <PDBx:U12>-0.0678</PDBx:U12>
         <PDBx:U13>0.0501</PDBx:U13>
         <PDBx:U22>0.4228</PDBx:U22>
         <PDBx:U23>-0.0823</PDBx:U23>
         <PDBx:U33>0.2186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1316">
         <PDBx:U11>0.1828</PDBx:U11>
         <PDBx:U12>-0.0471</PDBx:U12>
         <PDBx:U13>0.0307</PDBx:U13>
         <PDBx:U22>0.2177</PDBx:U22>
         <PDBx:U23>-0.0458</PDBx:U23>
         <PDBx:U33>0.0650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1317">
         <PDBx:U11>0.1875</PDBx:U11>
         <PDBx:U12>-0.0411</PDBx:U12>
         <PDBx:U13>0.0268</PDBx:U13>
         <PDBx:U22>0.2135</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.0674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1318">
         <PDBx:U11>0.2230</PDBx:U11>
         <PDBx:U12>-0.0435</PDBx:U12>
         <PDBx:U13>0.0297</PDBx:U13>
         <PDBx:U22>0.2421</PDBx:U22>
         <PDBx:U23>-0.0382</PDBx:U23>
         <PDBx:U33>0.0754</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1319">
         <PDBx:U11>0.2410</PDBx:U11>
         <PDBx:U12>-0.0506</PDBx:U12>
         <PDBx:U13>0.0336</PDBx:U13>
         <PDBx:U22>0.2567</PDBx:U22>
         <PDBx:U23>-0.0405</PDBx:U23>
         <PDBx:U33>0.0755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1320">
         <PDBx:U11>0.2330</PDBx:U11>
         <PDBx:U12>-0.0394</PDBx:U12>
         <PDBx:U13>0.0301</PDBx:U13>
         <PDBx:U22>0.2524</PDBx:U22>
         <PDBx:U23>-0.0403</PDBx:U23>
         <PDBx:U33>0.0768</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1321">
         <PDBx:U11>0.2423</PDBx:U11>
         <PDBx:U12>-0.0364</PDBx:U12>
         <PDBx:U13>0.0300</PDBx:U13>
         <PDBx:U22>0.2686</PDBx:U22>
         <PDBx:U23>-0.0448</PDBx:U23>
         <PDBx:U33>0.0967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1322">
         <PDBx:U11>0.2526</PDBx:U11>
         <PDBx:U12>-0.0339</PDBx:U12>
         <PDBx:U13>0.0263</PDBx:U13>
         <PDBx:U22>0.2643</PDBx:U22>
         <PDBx:U23>-0.0326</PDBx:U23>
         <PDBx:U33>0.0936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1323">
         <PDBx:U11>0.2943</PDBx:U11>
         <PDBx:U12>-0.0376</PDBx:U12>
         <PDBx:U13>0.0302</PDBx:U13>
         <PDBx:U22>0.3174</PDBx:U22>
         <PDBx:U23>-0.0429</PDBx:U23>
         <PDBx:U33>0.1453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1324">
         <PDBx:U11>0.1650</PDBx:U11>
         <PDBx:U12>-0.0393</PDBx:U12>
         <PDBx:U13>0.0217</PDBx:U13>
         <PDBx:U22>0.1827</PDBx:U22>
         <PDBx:U23>-0.0278</PDBx:U23>
         <PDBx:U33>0.0592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1325">
         <PDBx:U11>0.1827</PDBx:U11>
         <PDBx:U12>-0.0407</PDBx:U12>
         <PDBx:U13>0.0233</PDBx:U13>
         <PDBx:U22>0.1946</PDBx:U22>
         <PDBx:U23>-0.0273</PDBx:U23>
         <PDBx:U33>0.0581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1326">
         <PDBx:U11>0.2865</PDBx:U11>
         <PDBx:U12>-0.0441</PDBx:U12>
         <PDBx:U13>0.0289</PDBx:U13>
         <PDBx:U22>0.2875</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.1055</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1327">
         <PDBx:U11>0.3111</PDBx:U11>
         <PDBx:U12>-0.0496</PDBx:U12>
         <PDBx:U13>0.0308</PDBx:U13>
         <PDBx:U22>0.3086</PDBx:U22>
         <PDBx:U23>-0.0295</PDBx:U23>
         <PDBx:U33>0.1218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1328">
         <PDBx:U11>0.1875</PDBx:U11>
         <PDBx:U12>-0.0336</PDBx:U12>
         <PDBx:U13>0.0214</PDBx:U13>
         <PDBx:U22>0.1982</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.0574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1329">
         <PDBx:U11>0.1943</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.1985</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.0567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1330">
         <PDBx:U11>0.1683</PDBx:U11>
         <PDBx:U12>-0.0282</PDBx:U12>
         <PDBx:U13>0.0160</PDBx:U13>
         <PDBx:U22>0.1706</PDBx:U22>
         <PDBx:U23>-0.0167</PDBx:U23>
         <PDBx:U33>0.0542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1331">
         <PDBx:U11>0.2449</PDBx:U11>
         <PDBx:U12>-0.0241</PDBx:U12>
         <PDBx:U13>0.0197</PDBx:U13>
         <PDBx:U22>0.2467</PDBx:U22>
         <PDBx:U23>-0.0200</PDBx:U23>
         <PDBx:U33>0.0817</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1332">
         <PDBx:U11>0.2515</PDBx:U11>
         <PDBx:U12>-0.0420</PDBx:U12>
         <PDBx:U13>0.0258</PDBx:U13>
         <PDBx:U22>0.2469</PDBx:U22>
         <PDBx:U23>-0.0240</PDBx:U23>
         <PDBx:U33>0.0750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1333">
         <PDBx:U11>0.2615</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>0.0249</PDBx:U13>
         <PDBx:U22>0.2462</PDBx:U22>
         <PDBx:U23>-0.0198</PDBx:U23>
         <PDBx:U33>0.0723</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1334">
         <PDBx:U11>0.3049</PDBx:U11>
         <PDBx:U12>-0.0511</PDBx:U12>
         <PDBx:U13>0.0275</PDBx:U13>
         <PDBx:U22>0.2879</PDBx:U22>
         <PDBx:U23>-0.0221</PDBx:U23>
         <PDBx:U33>0.1017</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1335">
         <PDBx:U11>0.2621</PDBx:U11>
         <PDBx:U12>-0.0535</PDBx:U12>
         <PDBx:U13>0.0243</PDBx:U13>
         <PDBx:U22>0.2354</PDBx:U22>
         <PDBx:U23>-0.0173</PDBx:U23>
         <PDBx:U33>0.0622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1336">
         <PDBx:U11>0.2923</PDBx:U11>
         <PDBx:U12>-0.0398</PDBx:U12>
         <PDBx:U13>0.0214</PDBx:U13>
         <PDBx:U22>0.2698</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.0935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1337">
         <PDBx:U11>0.2857</PDBx:U11>
         <PDBx:U12>-0.0346</PDBx:U12>
         <PDBx:U13>0.0196</PDBx:U13>
         <PDBx:U22>0.2659</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.0940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1338">
         <PDBx:U11>0.2874</PDBx:U11>
         <PDBx:U12>-0.0364</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.2652</PDBx:U22>
         <PDBx:U23>-0.0124</PDBx:U23>
         <PDBx:U33>0.0915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1339">
         <PDBx:U11>0.2015</PDBx:U11>
         <PDBx:U12>-0.0294</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.1761</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.0705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1340">
         <PDBx:U11>0.3076</PDBx:U11>
         <PDBx:U12>-0.0535</PDBx:U12>
         <PDBx:U13>0.0307</PDBx:U13>
         <PDBx:U22>0.2998</PDBx:U22>
         <PDBx:U23>-0.0283</PDBx:U23>
         <PDBx:U33>0.1111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1341">
         <PDBx:U11>0.3341</PDBx:U11>
         <PDBx:U12>-0.0597</PDBx:U12>
         <PDBx:U13>0.0333</PDBx:U13>
         <PDBx:U22>0.3266</PDBx:U22>
         <PDBx:U23>-0.0313</PDBx:U23>
         <PDBx:U33>0.1327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1358">
         <PDBx:U11>1.0120</PDBx:U11>
         <PDBx:U12>-0.0870</PDBx:U12>
         <PDBx:U13>0.0317</PDBx:U13>
         <PDBx:U22>0.9684</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.7522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1359">
         <PDBx:U11>0.9950</PDBx:U11>
         <PDBx:U12>-0.0886</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.9275</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.7112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1360">
         <PDBx:U11>0.4766</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.4284</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.2398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1361">
         <PDBx:U11>0.4776</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>0.0159</PDBx:U13>
         <PDBx:U22>0.4295</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.2409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1362">
         <PDBx:U11>0.4637</PDBx:U11>
         <PDBx:U12>-0.0497</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.4120</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.2265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1363">
         <PDBx:U11>0.4652</PDBx:U11>
         <PDBx:U12>-0.0499</PDBx:U12>
         <PDBx:U13>0.0120</PDBx:U13>
         <PDBx:U22>0.4137</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.2281</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1364">
         <PDBx:U11>0.4680</PDBx:U11>
         <PDBx:U12>-0.0424</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.4244</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.2448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1365">
         <PDBx:U11>0.4693</PDBx:U11>
         <PDBx:U12>-0.0424</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.4257</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.2461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1366">
         <PDBx:U11>0.4523</PDBx:U11>
         <PDBx:U12>-0.0395</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.4147</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.2381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1367">
         <PDBx:U11>0.4545</PDBx:U11>
         <PDBx:U12>-0.0395</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.4168</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.2402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1368">
         <PDBx:U11>0.4845</PDBx:U11>
         <PDBx:U12>-0.0481</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.4210</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2374</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1369">
         <PDBx:U11>0.4872</PDBx:U11>
         <PDBx:U12>-0.0488</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.4236</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.2393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1370">
         <PDBx:U11>0.5442</PDBx:U11>
         <PDBx:U12>-0.0539</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.4703</PDBx:U22>
         <PDBx:U23>0.0011</PDBx:U23>
         <PDBx:U33>0.2819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1371">
         <PDBx:U11>0.5295</PDBx:U11>
         <PDBx:U12>-0.0446</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.4637</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.2838</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1372">
         <PDBx:U11>0.5699</PDBx:U11>
         <PDBx:U12>-0.0556</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.4966</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.3057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1373">
         <PDBx:U11>0.5626</PDBx:U11>
         <PDBx:U12>-0.0487</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.4909</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.3087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1374">
         <PDBx:U11>0.5803</PDBx:U11>
         <PDBx:U12>-0.0582</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.4943</PDBx:U22>
         <PDBx:U23>0.0034</PDBx:U23>
         <PDBx:U33>0.3036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1375">
         <PDBx:U11>0.5452</PDBx:U11>
         <PDBx:U12>-0.0373</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.4822</PDBx:U22>
         <PDBx:U23>0.0027</PDBx:U23>
         <PDBx:U33>0.3084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1376">
         <PDBx:U11>0.5757</PDBx:U11>
         <PDBx:U12>-0.0611</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.4908</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.2958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1377">
         <PDBx:U11>0.5507</PDBx:U11>
         <PDBx:U12>-0.0434</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.4788</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.3015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1378">
         <PDBx:U11>0.5874</PDBx:U11>
         <PDBx:U12>-0.0629</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.4941</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.2992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1379">
         <PDBx:U11>0.5448</PDBx:U11>
         <PDBx:U12>-0.0366</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.4782</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.3059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1380">
         <PDBx:U11>0.4072</PDBx:U11>
         <PDBx:U12>-0.0398</PDBx:U12>
         <PDBx:U13>0.0097</PDBx:U13>
         <PDBx:U22>0.3633</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1852</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1381">
         <PDBx:U11>0.3712</PDBx:U11>
         <PDBx:U12>-0.0337</PDBx:U12>
         <PDBx:U13>0.0094</PDBx:U13>
         <PDBx:U22>0.3334</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.1603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1382">
         <PDBx:U11>0.3529</PDBx:U11>
         <PDBx:U12>-0.0283</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.3122</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1383">
         <PDBx:U11>0.3268</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.2784</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.1101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1384">
         <PDBx:U11>0.3878</PDBx:U11>
         <PDBx:U12>-0.0340</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.3496</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.1754</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1385">
         <PDBx:U11>0.4697</PDBx:U11>
         <PDBx:U12>-0.0286</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.4367</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.2670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1386">
         <PDBx:U11>0.5142</PDBx:U11>
         <PDBx:U12>-0.0301</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.4818</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.3098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1387">
         <PDBx:U11>0.4793</PDBx:U11>
         <PDBx:U12>-0.0334</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.4390</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.2631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1388">
         <PDBx:U11>0.5060</PDBx:U11>
         <PDBx:U12>-0.0388</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.4645</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.2833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1389">
         <PDBx:U11>0.2885</PDBx:U11>
         <PDBx:U12>-0.0413</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.2542</PDBx:U22>
         <PDBx:U23>-0.0088</PDBx:U23>
         <PDBx:U33>0.0715</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1390">
         <PDBx:U11>0.3593</PDBx:U11>
         <PDBx:U12>-0.0419</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.3089</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.1243</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1391">
         <PDBx:U11>0.2902</PDBx:U11>
         <PDBx:U12>-0.0240</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.2553</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0910</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1392">
         <PDBx:U11>0.2653</PDBx:U11>
         <PDBx:U12>-0.0193</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.2290</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1393">
         <PDBx:U11>0.3016</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.2706</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.1137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1394">
         <PDBx:U11>0.3153</PDBx:U11>
         <PDBx:U12>-0.0163</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.2888</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1316</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1395">
         <PDBx:U11>0.3023</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.2664</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.1070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1396">
         <PDBx:U11>0.3066</PDBx:U11>
         <PDBx:U12>-0.0241</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.2656</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.1022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1397">
         <PDBx:U11>0.2914</PDBx:U11>
         <PDBx:U12>-0.0181</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.2627</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1049</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1398">
         <PDBx:U11>0.2536</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.2221</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.0762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1399">
         <PDBx:U11>0.2458</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.2185</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.0784</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1400">
         <PDBx:U11>0.2643</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.2369</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.0860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1401">
         <PDBx:U11>0.2643</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.2332</PDBx:U22>
         <PDBx:U23>-0.0001</PDBx:U23>
         <PDBx:U33>0.0806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1402">
         <PDBx:U11>0.1793</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1556</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.0603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1403">
         <PDBx:U11>0.1455</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1233</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1404">
         <PDBx:U11>0.1122</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0913</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1405">
         <PDBx:U11>0.0837</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0651</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.0383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1406">
         <PDBx:U11>0.2315</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.2124</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.0660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1407">
         <PDBx:U11>0.2492</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.2291</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1408">
         <PDBx:U11>0.2250</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.2084</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.0846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1409">
         <PDBx:U11>0.0915</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.0690</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1410">
         <PDBx:U11>0.0834</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.0619</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1411">
         <PDBx:U11>0.1220</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.1053</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1412">
         <PDBx:U11>0.1156</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1004</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1413">
         <PDBx:U11>0.1108</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.0863</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1414">
         <PDBx:U11>0.1834</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1520</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1415">
         <PDBx:U11>0.2926</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.2565</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1416">
         <PDBx:U11>0.2865</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>-0.0136</PDBx:U13>
         <PDBx:U22>0.2419</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1417">
         <PDBx:U11>0.4498</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.4040</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.2467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1418">
         <PDBx:U11>0.1001</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.0856</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1419">
         <PDBx:U11>0.1064</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.0952</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1420">
         <PDBx:U11>0.1344</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1233</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1421">
         <PDBx:U11>0.1166</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.1069</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1422">
         <PDBx:U11>0.0596</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0502</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1423">
         <PDBx:U11>0.0578</PDBx:U11>
         <PDBx:U12>-0.0051</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0511</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1424">
         <PDBx:U11>0.0570</PDBx:U11>
         <PDBx:U12>-0.0045</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.0523</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1425">
         <PDBx:U11>0.0820</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.0797</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.0410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1426">
         <PDBx:U11>0.1978</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1981</PDBx:U22>
         <PDBx:U23>-0.0154</PDBx:U23>
         <PDBx:U33>0.0662</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1427">
         <PDBx:U11>0.0861</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.0888</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1428">
         <PDBx:U11>0.1512</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1537</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.0476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1429">
         <PDBx:U11>0.0590</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0462</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1430">
         <PDBx:U11>0.0715</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.0586</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1431">
         <PDBx:U11>0.1306</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.1183</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.0533</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1432">
         <PDBx:U11>0.1194</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.1077</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.0465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1433">
         <PDBx:U11>0.0832</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.0688</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1434">
         <PDBx:U11>0.0983</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.0837</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1435">
         <PDBx:U11>0.1245</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1084</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1436">
         <PDBx:U11>0.1040</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.0905</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1437">
         <PDBx:U11>0.1098</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0932</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1438">
         <PDBx:U11>0.1083</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.0957</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1439">
         <PDBx:U11>0.1596</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.1454</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.0487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1440">
         <PDBx:U11>0.0980</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.0842</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1441">
         <PDBx:U11>0.1054</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.0928</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1442">
         <PDBx:U11>0.1028</PDBx:U11>
         <PDBx:U12>-0.0130</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.0910</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1443">
         <PDBx:U11>0.1663</PDBx:U11>
         <PDBx:U12>-0.0141</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1581</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.0535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1444">
         <PDBx:U11>0.0983</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.0911</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.0477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1445">
         <PDBx:U11>0.1377</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1232</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.0489</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1446">
         <PDBx:U11>0.1842</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.1661</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.0570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1447">
         <PDBx:U11>0.2284</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.2049</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.0539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1448">
         <PDBx:U11>0.2088</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.1803</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1449">
         <PDBx:U11>0.1292</PDBx:U11>
         <PDBx:U12>-0.0151</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.1230</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.0485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1450">
         <PDBx:U11>0.1315</PDBx:U11>
         <PDBx:U12>-0.0162</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.1292</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.0523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1451">
         <PDBx:U11>0.1400</PDBx:U11>
         <PDBx:U12>-0.0202</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.1393</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.0447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1452">
         <PDBx:U11>0.1270</PDBx:U11>
         <PDBx:U12>-0.0228</PDBx:U12>
         <PDBx:U13>0.0116</PDBx:U13>
         <PDBx:U22>0.1238</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1453">
         <PDBx:U11>0.1549</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.1555</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.0579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1454">
         <PDBx:U11>0.0991</PDBx:U11>
         <PDBx:U12>-0.0216</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.1018</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.0447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1455">
         <PDBx:U11>0.1066</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.1112</PDBx:U22>
         <PDBx:U23>-0.0127</PDBx:U23>
         <PDBx:U33>0.0455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0168</PDBx:U23>
         <PDBx:U33>0.0548</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.1319</PDBx:U11>
         <PDBx:U12>-0.0254</PDBx:U12>
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         <PDBx:U23>-0.0193</PDBx:U23>
         <PDBx:U33>0.0482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1745</PDBx:U11>
         <PDBx:U12>-0.0194</PDBx:U12>
         <PDBx:U13>0.0217</PDBx:U13>
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         <PDBx:U23>-0.0253</PDBx:U23>
         <PDBx:U33>0.0500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0182</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.1271</PDBx:U22>
         <PDBx:U23>-0.0155</PDBx:U23>
         <PDBx:U33>0.0442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>381</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.0765</PDBx:U11>
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         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.0857</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.0828</PDBx:U11>
         <PDBx:U12>-0.0371</PDBx:U12>
         <PDBx:U13>0.0120</PDBx:U13>
         <PDBx:U22>0.0937</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.0419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.1324</PDBx:U11>
         <PDBx:U12>-0.0369</PDBx:U12>
         <PDBx:U13>0.0165</PDBx:U13>
         <PDBx:U22>0.1365</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.0429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1464">
         <PDBx:U11>0.1398</PDBx:U11>
         <PDBx:U12>-0.0424</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.1425</PDBx:U22>
         <PDBx:U23>-0.0186</PDBx:U23>
         <PDBx:U33>0.0431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1465">
         <PDBx:U11>0.0826</PDBx:U11>
         <PDBx:U12>-0.0372</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.1004</PDBx:U22>
         <PDBx:U23>-0.0169</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1466">
         <PDBx:U11>0.2240</PDBx:U11>
         <PDBx:U12>-0.0285</PDBx:U12>
         <PDBx:U13>0.0273</PDBx:U13>
         <PDBx:U22>0.2393</PDBx:U22>
         <PDBx:U23>-0.0359</PDBx:U23>
         <PDBx:U33>0.0827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1467">
         <PDBx:U11>0.3815</PDBx:U11>
         <PDBx:U12>-0.0225</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>0.3954</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.2466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1468">
         <PDBx:U11>0.2139</PDBx:U11>
         <PDBx:U12>-0.0218</PDBx:U12>
         <PDBx:U13>0.0251</PDBx:U13>
         <PDBx:U22>0.2272</PDBx:U22>
         <PDBx:U23>-0.0341</PDBx:U23>
         <PDBx:U33>0.0798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3637</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0230</PDBx:U13>
         <PDBx:U22>0.3761</PDBx:U22>
         <PDBx:U23>-0.0331</PDBx:U23>
         <PDBx:U33>0.2317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.1022</PDBx:U11>
         <PDBx:U12>-0.0322</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.1020</PDBx:U22>
         <PDBx:U23>-0.0108</PDBx:U23>
         <PDBx:U33>0.0427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1471">
         <PDBx:U11>0.1083</PDBx:U11>
         <PDBx:U12>-0.0322</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.1018</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1472">
         <PDBx:U11>0.1455</PDBx:U11>
         <PDBx:U12>-0.0336</PDBx:U12>
         <PDBx:U13>0.0120</PDBx:U13>
         <PDBx:U22>0.1340</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1473">
         <PDBx:U11>0.1106</PDBx:U11>
         <PDBx:U12>-0.0375</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.0940</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1474">
         <PDBx:U11>0.1806</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.1721</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.0450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1475">
         <PDBx:U11>0.1778</PDBx:U11>
         <PDBx:U12>-0.0261</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1629</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1476">
         <PDBx:U11>0.1796</PDBx:U11>
         <PDBx:U12>-0.0243</PDBx:U12>
         <PDBx:U13>0.0164</PDBx:U13>
         <PDBx:U22>0.1751</PDBx:U22>
         <PDBx:U23>-0.0155</PDBx:U23>
         <PDBx:U33>0.0450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1477">
         <PDBx:U11>0.1263</PDBx:U11>
         <PDBx:U12>-0.0311</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.1159</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1478">
         <PDBx:U11>0.1121</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.0981</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1479">
         <PDBx:U11>0.2231</PDBx:U11>
         <PDBx:U12>-0.0379</PDBx:U12>
         <PDBx:U13>0.0155</PDBx:U13>
         <PDBx:U22>0.2081</PDBx:U22>
         <PDBx:U23>-0.0143</PDBx:U23>
         <PDBx:U33>0.0546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1480">
         <PDBx:U11>0.2372</PDBx:U11>
         <PDBx:U12>-0.0399</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.2157</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.0486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1481">
         <PDBx:U11>0.1000</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.0893</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.0404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1482">
         <PDBx:U11>0.1716</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.1606</PDBx:U22>
         <PDBx:U23>-0.0096</PDBx:U23>
         <PDBx:U33>0.0480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1483">
         <PDBx:U11>0.1798</PDBx:U11>
         <PDBx:U12>-0.0206</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.1722</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.0532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1484">
         <PDBx:U11>0.1519</PDBx:U11>
         <PDBx:U12>-0.0209</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.1359</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1485">
         <PDBx:U11>0.1674</PDBx:U11>
         <PDBx:U12>-0.0416</PDBx:U12>
         <PDBx:U13>0.0148</PDBx:U13>
         <PDBx:U22>0.1583</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.0497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1486">
         <PDBx:U11>0.1815</PDBx:U11>
         <PDBx:U12>-0.0486</PDBx:U12>
         <PDBx:U13>0.0174</PDBx:U13>
         <PDBx:U22>0.1726</PDBx:U22>
         <PDBx:U23>-0.0168</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1487">
         <PDBx:U11>0.2315</PDBx:U11>
         <PDBx:U12>-0.0540</PDBx:U12>
         <PDBx:U13>0.0234</PDBx:U13>
         <PDBx:U22>0.2217</PDBx:U22>
         <PDBx:U23>-0.0225</PDBx:U23>
         <PDBx:U33>0.0521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1488">
         <PDBx:U11>0.2136</PDBx:U11>
         <PDBx:U12>-0.0613</PDBx:U12>
         <PDBx:U13>0.0243</PDBx:U13>
         <PDBx:U22>0.2049</PDBx:U22>
         <PDBx:U23>-0.0238</PDBx:U23>
         <PDBx:U33>0.0440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1489">
         <PDBx:U11>0.2150</PDBx:U11>
         <PDBx:U12>-0.0492</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.2137</PDBx:U22>
         <PDBx:U23>-0.0243</PDBx:U23>
         <PDBx:U33>0.0546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1490">
         <PDBx:U11>0.3915</PDBx:U11>
         <PDBx:U12>-0.0475</PDBx:U12>
         <PDBx:U13>0.0299</PDBx:U13>
         <PDBx:U22>0.3975</PDBx:U22>
         <PDBx:U23>-0.0319</PDBx:U23>
         <PDBx:U33>0.2156</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1491">
         <PDBx:U11>0.3853</PDBx:U11>
         <PDBx:U12>-0.0480</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.3918</PDBx:U22>
         <PDBx:U23>-0.0328</PDBx:U23>
         <PDBx:U33>0.2100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1492">
         <PDBx:U11>0.4956</PDBx:U11>
         <PDBx:U12>-0.0458</PDBx:U12>
         <PDBx:U13>0.0315</PDBx:U13>
         <PDBx:U22>0.5068</PDBx:U22>
         <PDBx:U23>-0.0349</PDBx:U23>
         <PDBx:U33>0.3281</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1493">
         <PDBx:U11>0.1859</PDBx:U11>
         <PDBx:U12>-0.0519</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.1747</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.0478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1494">
         <PDBx:U11>0.2227</PDBx:U11>
         <PDBx:U12>-0.0563</PDBx:U12>
         <PDBx:U13>0.0227</PDBx:U13>
         <PDBx:U22>0.2104</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.0541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1495">
         <PDBx:U11>0.2539</PDBx:U11>
         <PDBx:U12>-0.0611</PDBx:U12>
         <PDBx:U13>0.0309</PDBx:U13>
         <PDBx:U22>0.2503</PDBx:U22>
         <PDBx:U23>-0.0310</PDBx:U23>
         <PDBx:U33>0.0602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1496">
         <PDBx:U11>0.2920</PDBx:U11>
         <PDBx:U12>-0.0676</PDBx:U12>
         <PDBx:U13>0.0337</PDBx:U13>
         <PDBx:U22>0.2876</PDBx:U22>
         <PDBx:U23>-0.0338</PDBx:U23>
         <PDBx:U33>0.0864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1497">
         <PDBx:U11>0.2723</PDBx:U11>
         <PDBx:U12>-0.0611</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.2498</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.0542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1498">
         <PDBx:U11>0.4709</PDBx:U11>
         <PDBx:U12>-0.0639</PDBx:U12>
         <PDBx:U13>0.0240</PDBx:U13>
         <PDBx:U22>0.4440</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.2439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1499">
         <PDBx:U11>0.4865</PDBx:U11>
         <PDBx:U12>-0.0592</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.4621</PDBx:U22>
         <PDBx:U23>-0.0201</PDBx:U23>
         <PDBx:U33>0.2669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1500">
         <PDBx:U11>0.5238</PDBx:U11>
         <PDBx:U12>-0.0712</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.4903</PDBx:U22>
         <PDBx:U23>-0.0200</PDBx:U23>
         <PDBx:U33>0.2836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1501">
         <PDBx:U11>0.1602</PDBx:U11>
         <PDBx:U12>-0.0591</PDBx:U12>
         <PDBx:U13>0.0239</PDBx:U13>
         <PDBx:U22>0.1648</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1502">
         <PDBx:U11>0.1828</PDBx:U11>
         <PDBx:U12>-0.0624</PDBx:U12>
         <PDBx:U13>0.0310</PDBx:U13>
         <PDBx:U22>0.1968</PDBx:U22>
         <PDBx:U23>-0.0351</PDBx:U23>
         <PDBx:U33>0.0492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1503">
         <PDBx:U11>0.2369</PDBx:U11>
         <PDBx:U12>-0.0581</PDBx:U12>
         <PDBx:U13>0.0379</PDBx:U13>
         <PDBx:U22>0.2548</PDBx:U22>
         <PDBx:U23>-0.0451</PDBx:U23>
         <PDBx:U33>0.0663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1504">
         <PDBx:U11>0.2658</PDBx:U11>
         <PDBx:U12>-0.0616</PDBx:U12>
         <PDBx:U13>0.0412</PDBx:U13>
         <PDBx:U22>0.2911</PDBx:U22>
         <PDBx:U23>-0.0518</PDBx:U23>
         <PDBx:U33>0.1005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1505">
         <PDBx:U11>0.2420</PDBx:U11>
         <PDBx:U12>-0.0593</PDBx:U12>
         <PDBx:U13>0.0389</PDBx:U13>
         <PDBx:U22>0.2619</PDBx:U22>
         <PDBx:U23>-0.0463</PDBx:U23>
         <PDBx:U33>0.0727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1506">
         <PDBx:U11>0.2455</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>0.0361</PDBx:U13>
         <PDBx:U22>0.2650</PDBx:U22>
         <PDBx:U23>-0.0436</PDBx:U23>
         <PDBx:U33>0.0843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1507">
         <PDBx:U11>0.1758</PDBx:U11>
         <PDBx:U12>-0.0526</PDBx:U12>
         <PDBx:U13>0.0280</PDBx:U13>
         <PDBx:U22>0.1898</PDBx:U22>
         <PDBx:U23>-0.0325</PDBx:U23>
         <PDBx:U33>0.0511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1508">
         <PDBx:U11>0.1803</PDBx:U11>
         <PDBx:U12>-0.0489</PDBx:U12>
         <PDBx:U13>0.0282</PDBx:U13>
         <PDBx:U22>0.1975</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.0572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1509">
         <PDBx:U11>0.2557</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>0.0366</PDBx:U13>
         <PDBx:U22>0.2741</PDBx:U22>
         <PDBx:U23>-0.0448</PDBx:U23>
         <PDBx:U33>0.0895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1510">
         <PDBx:U11>0.2506</PDBx:U11>
         <PDBx:U12>-0.0597</PDBx:U12>
         <PDBx:U13>0.0369</PDBx:U13>
         <PDBx:U22>0.2629</PDBx:U22>
         <PDBx:U23>-0.0424</PDBx:U23>
         <PDBx:U33>0.0719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1511">
         <PDBx:U11>0.2211</PDBx:U11>
         <PDBx:U12>-0.0414</PDBx:U12>
         <PDBx:U13>0.0290</PDBx:U13>
         <PDBx:U22>0.2317</PDBx:U22>
         <PDBx:U23>-0.0339</PDBx:U23>
         <PDBx:U33>0.0648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1512">
         <PDBx:U11>0.2335</PDBx:U11>
         <PDBx:U12>-0.0364</PDBx:U12>
         <PDBx:U13>0.0291</PDBx:U13>
         <PDBx:U22>0.2480</PDBx:U22>
         <PDBx:U23>-0.0366</PDBx:U23>
         <PDBx:U33>0.0806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1513">
         <PDBx:U11>0.2502</PDBx:U11>
         <PDBx:U12>-0.0437</PDBx:U12>
         <PDBx:U13>0.0281</PDBx:U13>
         <PDBx:U22>0.2522</PDBx:U22>
         <PDBx:U23>-0.0296</PDBx:U23>
         <PDBx:U33>0.0750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1514">
         <PDBx:U11>0.1936</PDBx:U11>
         <PDBx:U12>-0.0304</PDBx:U12>
         <PDBx:U13>0.0239</PDBx:U13>
         <PDBx:U22>0.2038</PDBx:U22>
         <PDBx:U23>-0.0293</PDBx:U23>
         <PDBx:U33>0.0553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1515">
         <PDBx:U11>0.2137</PDBx:U11>
         <PDBx:U12>-0.0539</PDBx:U12>
         <PDBx:U13>0.0352</PDBx:U13>
         <PDBx:U22>0.2404</PDBx:U22>
         <PDBx:U23>-0.0465</PDBx:U23>
         <PDBx:U33>0.0759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1516">
         <PDBx:U11>0.2149</PDBx:U11>
         <PDBx:U12>-0.0597</PDBx:U12>
         <PDBx:U13>0.0376</PDBx:U13>
         <PDBx:U22>0.2450</PDBx:U22>
         <PDBx:U23>-0.0501</PDBx:U23>
         <PDBx:U33>0.0773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1517">
         <PDBx:U11>0.2385</PDBx:U11>
         <PDBx:U12>-0.0549</PDBx:U12>
         <PDBx:U13>0.0384</PDBx:U13>
         <PDBx:U22>0.2633</PDBx:U22>
         <PDBx:U23>-0.0502</PDBx:U23>
         <PDBx:U33>0.0777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1518">
         <PDBx:U11>0.2088</PDBx:U11>
         <PDBx:U12>-0.0488</PDBx:U12>
         <PDBx:U13>0.0360</PDBx:U13>
         <PDBx:U22>0.2370</PDBx:U22>
         <PDBx:U23>-0.0501</PDBx:U23>
         <PDBx:U33>0.0611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1519">
         <PDBx:U11>0.2485</PDBx:U11>
         <PDBx:U12>-0.0597</PDBx:U12>
         <PDBx:U13>0.0433</PDBx:U13>
         <PDBx:U22>0.2903</PDBx:U22>
         <PDBx:U23>-0.0637</PDBx:U23>
         <PDBx:U33>0.1060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1520">
         <PDBx:U11>0.3913</PDBx:U11>
         <PDBx:U12>-0.0659</PDBx:U12>
         <PDBx:U13>0.0475</PDBx:U13>
         <PDBx:U22>0.4384</PDBx:U22>
         <PDBx:U23>-0.0707</PDBx:U23>
         <PDBx:U33>0.2445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1521">
         <PDBx:U11>0.2092</PDBx:U11>
         <PDBx:U12>-0.0708</PDBx:U12>
         <PDBx:U13>0.0445</PDBx:U13>
         <PDBx:U22>0.2509</PDBx:U22>
         <PDBx:U23>-0.0622</PDBx:U23>
         <PDBx:U33>0.0712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1522">
         <PDBx:U11>0.3596</PDBx:U11>
         <PDBx:U12>-0.0674</PDBx:U12>
         <PDBx:U13>0.0502</PDBx:U13>
         <PDBx:U22>0.4181</PDBx:U22>
         <PDBx:U23>-0.0803</PDBx:U23>
         <PDBx:U33>0.2239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1523">
         <PDBx:U11>0.2589</PDBx:U11>
         <PDBx:U12>-0.0585</PDBx:U12>
         <PDBx:U13>0.0377</PDBx:U13>
         <PDBx:U22>0.2754</PDBx:U22>
         <PDBx:U23>-0.0454</PDBx:U23>
         <PDBx:U33>0.0853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1524">
         <PDBx:U11>0.2859</PDBx:U11>
         <PDBx:U12>-0.0546</PDBx:U12>
         <PDBx:U13>0.0351</PDBx:U13>
         <PDBx:U22>0.2974</PDBx:U22>
         <PDBx:U23>-0.0407</PDBx:U23>
         <PDBx:U33>0.1102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1525">
         <PDBx:U11>0.3142</PDBx:U11>
         <PDBx:U12>-0.0563</PDBx:U12>
         <PDBx:U13>0.0372</PDBx:U13>
         <PDBx:U22>0.3318</PDBx:U22>
         <PDBx:U23>-0.0455</PDBx:U23>
         <PDBx:U33>0.1430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1526">
         <PDBx:U11>0.3011</PDBx:U11>
         <PDBx:U12>-0.0527</PDBx:U12>
         <PDBx:U13>0.0351</PDBx:U13>
         <PDBx:U22>0.3158</PDBx:U22>
         <PDBx:U23>-0.0422</PDBx:U23>
         <PDBx:U33>0.1299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1527">
         <PDBx:U11>0.3453</PDBx:U11>
         <PDBx:U12>-0.0568</PDBx:U12>
         <PDBx:U13>0.0329</PDBx:U13>
         <PDBx:U22>0.3453</PDBx:U22>
         <PDBx:U23>-0.0339</PDBx:U23>
         <PDBx:U33>0.1553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1528">
         <PDBx:U11>0.4146</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>0.0290</PDBx:U13>
         <PDBx:U22>0.4093</PDBx:U22>
         <PDBx:U23>-0.0282</PDBx:U23>
         <PDBx:U33>0.2242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1529">
         <PDBx:U11>0.5044</PDBx:U11>
         <PDBx:U12>-0.0517</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>0.4857</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.2991</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1530">
         <PDBx:U11>0.4711</PDBx:U11>
         <PDBx:U12>-0.0574</PDBx:U12>
         <PDBx:U13>0.0257</PDBx:U13>
         <PDBx:U22>0.4495</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.2574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1531">
         <PDBx:U11>0.2465</PDBx:U11>
         <PDBx:U12>-0.0611</PDBx:U12>
         <PDBx:U13>0.0412</PDBx:U13>
         <PDBx:U22>0.2734</PDBx:U22>
         <PDBx:U23>-0.0539</PDBx:U23>
         <PDBx:U33>0.0807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1532">
         <PDBx:U11>0.2434</PDBx:U11>
         <PDBx:U12>-0.0624</PDBx:U12>
         <PDBx:U13>0.0434</PDBx:U13>
         <PDBx:U22>0.2783</PDBx:U22>
         <PDBx:U23>-0.0603</PDBx:U23>
         <PDBx:U33>0.0843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1533">
         <PDBx:U11>0.2990</PDBx:U11>
         <PDBx:U12>-0.0550</PDBx:U12>
         <PDBx:U13>0.0418</PDBx:U13>
         <PDBx:U22>0.3429</PDBx:U22>
         <PDBx:U23>-0.0649</PDBx:U23>
         <PDBx:U33>0.1566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1534">
         <PDBx:U11>0.3226</PDBx:U11>
         <PDBx:U12>-0.0545</PDBx:U12>
         <PDBx:U13>0.0427</PDBx:U13>
         <PDBx:U22>0.3746</PDBx:U22>
         <PDBx:U23>-0.0712</PDBx:U23>
         <PDBx:U33>0.1887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1535">
         <PDBx:U11>0.3047</PDBx:U11>
         <PDBx:U12>-0.0729</PDBx:U12>
         <PDBx:U13>0.0488</PDBx:U13>
         <PDBx:U22>0.3449</PDBx:U22>
         <PDBx:U23>-0.0678</PDBx:U23>
         <PDBx:U33>0.1412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1536">
         <PDBx:U11>0.4715</PDBx:U11>
         <PDBx:U12>-0.0815</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.5015</PDBx:U22>
         <PDBx:U23>-0.0638</PDBx:U23>
         <PDBx:U33>0.2896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1537">
         <PDBx:U11>0.5847</PDBx:U11>
         <PDBx:U12>-0.0838</PDBx:U12>
         <PDBx:U13>0.0498</PDBx:U13>
         <PDBx:U22>0.6075</PDBx:U22>
         <PDBx:U23>-0.0601</PDBx:U23>
         <PDBx:U33>0.3930</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1538">
         <PDBx:U11>0.6854</PDBx:U11>
         <PDBx:U12>-0.0950</PDBx:U12>
         <PDBx:U13>0.0528</PDBx:U13>
         <PDBx:U22>0.7011</PDBx:U22>
         <PDBx:U23>-0.0601</PDBx:U23>
         <PDBx:U33>0.4766</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1539">
         <PDBx:U11>0.8139</PDBx:U11>
         <PDBx:U12>-0.0979</PDBx:U12>
         <PDBx:U13>0.0526</PDBx:U13>
         <PDBx:U22>0.8227</PDBx:U22>
         <PDBx:U23>-0.0575</PDBx:U23>
         <PDBx:U33>0.5957</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1540">
         <PDBx:U11>0.2240</PDBx:U11>
         <PDBx:U12>-0.0495</PDBx:U12>
         <PDBx:U13>0.0391</PDBx:U13>
         <PDBx:U22>0.2663</PDBx:U22>
         <PDBx:U23>-0.0622</PDBx:U23>
         <PDBx:U33>0.0862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1541">
         <PDBx:U11>0.2079</PDBx:U11>
         <PDBx:U12>-0.0424</PDBx:U12>
         <PDBx:U13>0.0368</PDBx:U13>
         <PDBx:U22>0.2563</PDBx:U22>
         <PDBx:U23>-0.0658</PDBx:U23>
         <PDBx:U33>0.0843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1542">
         <PDBx:U11>0.2042</PDBx:U11>
         <PDBx:U12>-0.0344</PDBx:U12>
         <PDBx:U13>0.0320</PDBx:U13>
         <PDBx:U22>0.2459</PDBx:U22>
         <PDBx:U23>-0.0585</PDBx:U23>
         <PDBx:U33>0.0815</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1543">
         <PDBx:U11>0.2229</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0301</PDBx:U13>
         <PDBx:U22>0.2580</PDBx:U22>
         <PDBx:U23>-0.0526</PDBx:U23>
         <PDBx:U33>0.0962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1544">
         <PDBx:U11>0.2170</PDBx:U11>
         <PDBx:U12>-0.0430</PDBx:U12>
         <PDBx:U13>0.0379</PDBx:U13>
         <PDBx:U22>0.2690</PDBx:U22>
         <PDBx:U23>-0.0695</PDBx:U23>
         <PDBx:U33>0.0983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1545">
         <PDBx:U11>0.2645</PDBx:U11>
         <PDBx:U12>-0.0368</PDBx:U12>
         <PDBx:U13>0.0358</PDBx:U13>
         <PDBx:U22>0.3233</PDBx:U22>
         <PDBx:U23>-0.0751</PDBx:U23>
         <PDBx:U33>0.1606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1546">
         <PDBx:U11>0.2875</PDBx:U11>
         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>0.0335</PDBx:U13>
         <PDBx:U22>0.3439</PDBx:U22>
         <PDBx:U23>-0.0733</PDBx:U23>
         <PDBx:U33>0.1878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1547">
         <PDBx:U11>0.2815</PDBx:U11>
         <PDBx:U12>-0.0349</PDBx:U12>
         <PDBx:U13>0.0355</PDBx:U13>
         <PDBx:U22>0.3489</PDBx:U22>
         <PDBx:U23>-0.0828</PDBx:U23>
         <PDBx:U33>0.1887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1548">
         <PDBx:U11>0.2794</PDBx:U11>
         <PDBx:U12>-0.0275</PDBx:U12>
         <PDBx:U13>0.0316</PDBx:U13>
         <PDBx:U22>0.3422</PDBx:U22>
         <PDBx:U23>-0.0797</PDBx:U23>
         <PDBx:U33>0.1926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1549">
         <PDBx:U11>0.2848</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>0.0325</PDBx:U13>
         <PDBx:U22>0.3546</PDBx:U22>
         <PDBx:U23>-0.0857</PDBx:U23>
         <PDBx:U33>0.2029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1550">
         <PDBx:U11>0.1496</PDBx:U11>
         <PDBx:U12>-0.0323</PDBx:U12>
         <PDBx:U13>0.0246</PDBx:U13>
         <PDBx:U22>0.1957</PDBx:U22>
         <PDBx:U23>-0.0484</PDBx:U23>
         <PDBx:U33>0.0677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1551">
         <PDBx:U11>0.1256</PDBx:U11>
         <PDBx:U12>-0.0263</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.1665</PDBx:U22>
         <PDBx:U23>-0.0366</PDBx:U23>
         <PDBx:U33>0.0635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1552">
         <PDBx:U11>0.1713</PDBx:U11>
         <PDBx:U12>-0.0185</PDBx:U12>
         <PDBx:U13>0.0215</PDBx:U13>
         <PDBx:U22>0.2073</PDBx:U22>
         <PDBx:U23>-0.0490</PDBx:U23>
         <PDBx:U33>0.0672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1553">
         <PDBx:U11>0.1646</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.1931</PDBx:U22>
         <PDBx:U23>-0.0420</PDBx:U23>
         <PDBx:U33>0.0571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1554">
         <PDBx:U11>0.1393</PDBx:U11>
         <PDBx:U12>-0.0231</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.1829</PDBx:U22>
         <PDBx:U23>-0.0424</PDBx:U23>
         <PDBx:U33>0.0670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1555">
         <PDBx:U11>0.1609</PDBx:U11>
         <PDBx:U12>-0.0167</PDBx:U12>
         <PDBx:U13>0.0170</PDBx:U13>
         <PDBx:U22>0.1962</PDBx:U22>
         <PDBx:U23>-0.0404</PDBx:U23>
         <PDBx:U33>0.0720</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1556">
         <PDBx:U11>0.2037</PDBx:U11>
         <PDBx:U12>-0.0174</PDBx:U12>
         <PDBx:U13>0.0199</PDBx:U13>
         <PDBx:U22>0.2305</PDBx:U22>
         <PDBx:U23>-0.0403</PDBx:U23>
         <PDBx:U33>0.0825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1557">
         <PDBx:U11>0.1725</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.2069</PDBx:U22>
         <PDBx:U23>-0.0426</PDBx:U23>
         <PDBx:U33>0.0820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1558">
         <PDBx:U11>0.2077</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0165</PDBx:U13>
         <PDBx:U22>0.2286</PDBx:U22>
         <PDBx:U23>-0.0342</PDBx:U23>
         <PDBx:U33>0.0854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1559">
         <PDBx:U11>0.2036</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.2296</PDBx:U22>
         <PDBx:U23>-0.0412</PDBx:U23>
         <PDBx:U33>0.0928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1560">
         <PDBx:U11>0.1918</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.2132</PDBx:U22>
         <PDBx:U23>-0.0313</PDBx:U23>
         <PDBx:U33>0.0889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1561">
         <PDBx:U11>0.1504</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0198</PDBx:U13>
         <PDBx:U22>0.1942</PDBx:U22>
         <PDBx:U23>-0.0517</PDBx:U23>
         <PDBx:U33>0.0676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1562">
         <PDBx:U11>0.1621</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0185</PDBx:U13>
         <PDBx:U22>0.2023</PDBx:U22>
         <PDBx:U23>-0.0552</PDBx:U23>
         <PDBx:U33>0.0717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1563">
         <PDBx:U11>0.1609</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.1954</PDBx:U22>
         <PDBx:U23>-0.0485</PDBx:U23>
         <PDBx:U33>0.0677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1564">
         <PDBx:U11>0.1033</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.1356</PDBx:U22>
         <PDBx:U23>-0.0298</PDBx:U23>
         <PDBx:U33>0.0547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1565">
         <PDBx:U11>0.1922</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>0.0193</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>-0.0667</PDBx:U23>
         <PDBx:U33>0.1076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1566">
         <PDBx:U11>0.3722</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.4165</PDBx:U22>
         <PDBx:U23>-0.0663</PDBx:U23>
         <PDBx:U33>0.2938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1567">
         <PDBx:U11>0.6869</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.7271</PDBx:U22>
         <PDBx:U23>-0.0645</PDBx:U23>
         <PDBx:U33>0.6118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1568">
         <PDBx:U11>0.5830</PDBx:U11>
         <PDBx:U12>0.0077</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.6170</PDBx:U22>
         <PDBx:U23>-0.0621</PDBx:U23>
         <PDBx:U33>0.5093</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1569">
         <PDBx:U11>0.6295</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.6725</PDBx:U22>
         <PDBx:U23>-0.0656</PDBx:U23>
         <PDBx:U33>0.5552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1570">
         <PDBx:U11>0.1252</PDBx:U11>
         <PDBx:U12>-0.0216</PDBx:U12>
         <PDBx:U13>0.0177</PDBx:U13>
         <PDBx:U22>0.1631</PDBx:U22>
         <PDBx:U23>-0.0383</PDBx:U23>
         <PDBx:U33>0.0601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1571">
         <PDBx:U11>0.1052</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>0.0153</PDBx:U13>
         <PDBx:U22>0.1377</PDBx:U22>
         <PDBx:U23>-0.0290</PDBx:U23>
         <PDBx:U33>0.0531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1572">
         <PDBx:U11>0.1005</PDBx:U11>
         <PDBx:U12>-0.0204</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.1238</PDBx:U22>
         <PDBx:U23>-0.0216</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1573">
         <PDBx:U11>0.0880</PDBx:U11>
         <PDBx:U12>-0.0183</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1070</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.0434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1574">
         <PDBx:U11>0.2040</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>0.0288</PDBx:U13>
         <PDBx:U22>0.2341</PDBx:U22>
         <PDBx:U23>-0.0487</PDBx:U23>
         <PDBx:U33>0.0777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1575">
         <PDBx:U11>0.4007</PDBx:U11>
         <PDBx:U12>-0.0323</PDBx:U12>
         <PDBx:U13>0.0317</PDBx:U13>
         <PDBx:U22>0.4392</PDBx:U22>
         <PDBx:U23>-0.0569</PDBx:U23>
         <PDBx:U33>0.2808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1576">
         <PDBx:U11>0.0825</PDBx:U11>
         <PDBx:U12>-0.0207</PDBx:U12>
         <PDBx:U13>0.0094</PDBx:U13>
         <PDBx:U22>0.1039</PDBx:U22>
         <PDBx:U23>-0.0157</PDBx:U23>
         <PDBx:U33>0.0479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1577">
         <PDBx:U11>0.0643</PDBx:U11>
         <PDBx:U12>-0.0177</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.0781</PDBx:U22>
         <PDBx:U23>-0.0093</PDBx:U23>
         <PDBx:U33>0.0404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1578">
         <PDBx:U11>0.0760</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.0875</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.0407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1579">
         <PDBx:U11>0.0758</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.0817</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.0421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1580">
         <PDBx:U11>0.0867</PDBx:U11>
         <PDBx:U12>-0.0188</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.0988</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1581">
         <PDBx:U11>0.1160</PDBx:U11>
         <PDBx:U12>-0.0241</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.1251</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.0500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1582">
         <PDBx:U11>0.1567</PDBx:U11>
         <PDBx:U12>-0.0238</PDBx:U12>
         <PDBx:U13>0.0148</PDBx:U13>
         <PDBx:U22>0.1588</PDBx:U22>
         <PDBx:U23>-0.0163</PDBx:U23>
         <PDBx:U33>0.0512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1583">
         <PDBx:U11>0.1801</PDBx:U11>
         <PDBx:U12>-0.0285</PDBx:U12>
         <PDBx:U13>0.0203</PDBx:U13>
         <PDBx:U22>0.1927</PDBx:U22>
         <PDBx:U23>-0.0266</PDBx:U23>
         <PDBx:U33>0.0621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1584">
         <PDBx:U11>0.1842</PDBx:U11>
         <PDBx:U12>-0.0286</PDBx:U12>
         <PDBx:U13>0.0177</PDBx:U13>
         <PDBx:U22>0.1823</PDBx:U22>
         <PDBx:U23>-0.0178</PDBx:U23>
         <PDBx:U33>0.0530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1585">
         <PDBx:U11>0.2181</PDBx:U11>
         <PDBx:U12>-0.0340</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>0.2264</PDBx:U22>
         <PDBx:U23>-0.0296</PDBx:U23>
         <PDBx:U33>0.0663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1586">
         <PDBx:U11>0.1856</PDBx:U11>
         <PDBx:U12>-0.0344</PDBx:U12>
         <PDBx:U13>0.0196</PDBx:U13>
         <PDBx:U22>0.1864</PDBx:U22>
         <PDBx:U23>-0.0205</PDBx:U23>
         <PDBx:U33>0.0567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1587">
         <PDBx:U11>0.0653</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.0818</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1588">
         <PDBx:U11>0.0585</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.0721</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1589">
         <PDBx:U11>0.0825</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.0929</PDBx:U22>
         <PDBx:U23>-0.0124</PDBx:U23>
         <PDBx:U33>0.0425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1590">
         <PDBx:U11>0.0585</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.0633</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1591">
         <PDBx:U11>0.0879</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.1060</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.0446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1592">
         <PDBx:U11>0.2389</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.2554</PDBx:U22>
         <PDBx:U23>-0.0370</PDBx:U23>
         <PDBx:U33>0.1308</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1593">
         <PDBx:U11>0.3278</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.3512</PDBx:U22>
         <PDBx:U23>-0.0447</PDBx:U23>
         <PDBx:U33>0.2301</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1594">
         <PDBx:U11>0.3816</PDBx:U11>
         <PDBx:U12>0.0092</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.4013</PDBx:U22>
         <PDBx:U23>-0.0441</PDBx:U23>
         <PDBx:U33>0.2879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1595">
         <PDBx:U11>0.3100</PDBx:U11>
         <PDBx:U12>0.0117</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.3368</PDBx:U22>
         <PDBx:U23>-0.0522</PDBx:U23>
         <PDBx:U33>0.2269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1596">
         <PDBx:U11>0.0833</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.0994</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.0461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1597">
         <PDBx:U11>0.0640</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0796</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.0414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1598">
         <PDBx:U11>0.0824</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.0909</PDBx:U22>
         <PDBx:U23>-0.0119</PDBx:U23>
         <PDBx:U33>0.0418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1599">
         <PDBx:U11>0.0696</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0744</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1600">
         <PDBx:U11>0.0625</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.0864</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.0431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1601">
         <PDBx:U11>0.1611</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.1850</PDBx:U22>
         <PDBx:U23>-0.0430</PDBx:U23>
         <PDBx:U33>0.0771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1602">
         <PDBx:U11>0.1386</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>0.0159</PDBx:U13>
         <PDBx:U22>0.1723</PDBx:U22>
         <PDBx:U23>-0.0481</PDBx:U23>
         <PDBx:U33>0.0640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1603">
         <PDBx:U11>0.2417</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>0.0168</PDBx:U13>
         <PDBx:U22>0.2791</PDBx:U22>
         <PDBx:U23>-0.0627</PDBx:U23>
         <PDBx:U33>0.1596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1604">
         <PDBx:U11>0.4715</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>0.0197</PDBx:U13>
         <PDBx:U22>0.5183</PDBx:U22>
         <PDBx:U23>-0.0710</PDBx:U23>
         <PDBx:U33>0.3958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1605">
         <PDBx:U11>0.2874</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.0245</PDBx:U13>
         <PDBx:U22>0.3378</PDBx:U22>
         <PDBx:U23>-0.0721</PDBx:U23>
         <PDBx:U33>0.2064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1606">
         <PDBx:U11>0.3420</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.3946</PDBx:U22>
         <PDBx:U23>-0.0785</PDBx:U23>
         <PDBx:U33>0.2779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1607">
         <PDBx:U11>0.0597</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.0678</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1608">
         <PDBx:U11>0.0666</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.0695</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1609">
         <PDBx:U11>0.1188</PDBx:U11>
         <PDBx:U12>-0.0064</PDBx:U12>
         <PDBx:U13>0.0080</PDBx:U13>
         <PDBx:U22>0.1158</PDBx:U22>
         <PDBx:U23>-0.0102</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1610">
         <PDBx:U11>0.1154</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1094</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.0425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1611">
         <PDBx:U11>0.0619</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.0646</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1612">
         <PDBx:U11>0.0620</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.0590</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1613">
         <PDBx:U11>0.0559</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.0479</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1614">
         <PDBx:U11>0.1174</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.1060</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.0468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1615">
         <PDBx:U11>0.0643</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0488</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1616">
         <PDBx:U11>0.0556</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.0481</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1617">
         <PDBx:U11>0.0981</PDBx:U11>
         <PDBx:U12>-0.0014</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.0909</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.0431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1618">
         <PDBx:U11>0.1113</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1030</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1619">
         <PDBx:U11>0.1425</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1361</PDBx:U22>
         <PDBx:U23>-0.0087</PDBx:U23>
         <PDBx:U33>0.0519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1620">
         <PDBx:U11>0.0772</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.0687</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.0424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1621">
         <PDBx:U11>0.0771</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.0651</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.0435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1622">
         <PDBx:U11>0.0945</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.0807</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.0417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1623">
         <PDBx:U11>0.0686</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.0498</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1624">
         <PDBx:U11>0.1052</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.0964</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.0467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1625">
         <PDBx:U11>0.0946</PDBx:U11>
         <PDBx:U12>0.0077</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.0878</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.0483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1626">
         <PDBx:U11>0.1531</PDBx:U11>
         <PDBx:U12>0.0078</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.1372</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.0500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1627">
         <PDBx:U11>0.2276</PDBx:U11>
         <PDBx:U12>0.0107</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.2102</PDBx:U22>
         <PDBx:U23>-0.0210</PDBx:U23>
         <PDBx:U33>0.1082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1628">
         <PDBx:U11>0.0595</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.0509</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1629">
         <PDBx:U11>0.0664</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.0570</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1630">
         <PDBx:U11>0.1016</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.0876</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1631">
         <PDBx:U11>0.0970</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.0803</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1632">
         <PDBx:U11>0.0722</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.0676</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1633">
         <PDBx:U11>0.0588</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.0534</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1634">
         <PDBx:U11>0.0815</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.0770</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1635">
         <PDBx:U11>0.0593</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.0521</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1636">
         <PDBx:U11>0.1224</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.1175</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.0424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1637">
         <PDBx:U11>0.0587</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.0512</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1638">
         <PDBx:U11>0.1278</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.1217</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.0505</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1639">
         <PDBx:U11>0.1662</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0137</PDBx:U13>
         <PDBx:U22>0.1606</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.0561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1640">
         <PDBx:U11>0.0703</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.0564</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1641">
         <PDBx:U11>0.0793</PDBx:U11>
         <PDBx:U12>-0.0028</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.0628</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1642">
         <PDBx:U11>0.1235</PDBx:U11>
         <PDBx:U12>-0.0014</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.1025</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1643">
         <PDBx:U11>0.1023</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0793</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1644">
         <PDBx:U11>0.0933</PDBx:U11>
         <PDBx:U12>-0.0028</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.0777</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1645">
         <PDBx:U11>0.0855</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.0626</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.0418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1646">
         <PDBx:U11>0.1066</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.0776</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1647">
         <PDBx:U11>0.1390</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1069</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1648">
         <PDBx:U11>0.1257</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.0890</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1649">
         <PDBx:U11>0.1375</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.1062</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1650">
         <PDBx:U11>0.2172</PDBx:U11>
         <PDBx:U12>0.0038</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1781</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.0688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1651">
         <PDBx:U11>0.2740</PDBx:U11>
         <PDBx:U12>0.0068</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.2325</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1276</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1652">
         <PDBx:U11>0.2293</PDBx:U11>
         <PDBx:U12>0.0095</PDBx:U12>
         <PDBx:U13>-0.0054</PDBx:U13>
         <PDBx:U22>0.1859</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.0883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1653">
         <PDBx:U11>0.1155</PDBx:U11>
         <PDBx:U12>0.0004</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.0861</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1654">
         <PDBx:U11>0.1120</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.0802</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1655">
         <PDBx:U11>0.1248</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.0938</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1656">
         <PDBx:U11>0.1239</PDBx:U11>
         <PDBx:U12>-0.0045</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.0886</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1657">
         <PDBx:U11>0.0650</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.0392</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1658">
         <PDBx:U11>0.0670</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.0426</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.0406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1659">
         <PDBx:U11>0.1162</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.0883</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1660">
         <PDBx:U11>0.0804</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0509</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1661">
         <PDBx:U11>0.0601</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0407</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1662">
         <PDBx:U11>0.0858</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.0700</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1663">
         <PDBx:U11>0.0775</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.0645</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1664">
         <PDBx:U11>0.0601</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.0453</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1665">
         <PDBx:U11>0.0674</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0388</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1666">
         <PDBx:U11>0.0708</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0391</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1667">
         <PDBx:U11>0.1276</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.0877</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1668">
         <PDBx:U11>0.1262</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.0848</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1669">
         <PDBx:U11>0.1240</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.0910</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.0426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1670">
         <PDBx:U11>0.1161</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.0786</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1671">
         <PDBx:U11>0.1223</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.0949</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1672">
         <PDBx:U11>0.0821</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.0389</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1673">
         <PDBx:U11>0.0914</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.0391</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.0382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1674">
         <PDBx:U11>0.1435</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.0913</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1675">
         <PDBx:U11>0.1497</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.0915</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1676">
         <PDBx:U11>0.1116</PDBx:U11>
         <PDBx:U12>-0.0045</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.0559</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1677">
         <PDBx:U11>0.1309</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.0714</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.0406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1678">
         <PDBx:U11>0.1276</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.0703</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1679">
         <PDBx:U11>0.1999</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1342</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1680">
         <PDBx:U11>0.1589</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.0984</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1681">
         <PDBx:U11>0.2276</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0066</PDBx:U13>
         <PDBx:U22>0.1584</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.0672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1682">
         <PDBx:U11>0.1944</PDBx:U11>
         <PDBx:U12>0.0034</PDBx:U12>
         <PDBx:U13>-0.0060</PDBx:U13>
         <PDBx:U22>0.1283</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1683">
         <PDBx:U11>0.0882</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0429</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1684">
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         <PDBx:U12>-0.0133</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.0645</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1685">
         <PDBx:U11>0.1058</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.0638</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.0419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1686">
         <PDBx:U11>0.1159</PDBx:U11>
         <PDBx:U12>-0.0201</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.0699</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.0535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1687">
         <PDBx:U11>0.1120</PDBx:U11>
         <PDBx:U12>-0.0122</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.0759</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1688">
         <PDBx:U11>0.1332</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.1002</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.0562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1689">
         <PDBx:U11>0.1853</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>0.0163</PDBx:U13>
         <PDBx:U22>0.1504</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.0608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1690">
         <PDBx:U11>0.1280</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1014</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.0561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1691">
         <PDBx:U11>0.1795</PDBx:U11>
         <PDBx:U12>-0.0179</PDBx:U12>
         <PDBx:U13>0.0177</PDBx:U13>
         <PDBx:U22>0.1495</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.0606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1692">
         <PDBx:U11>0.1840</PDBx:U11>
         <PDBx:U12>-0.0177</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.1595</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.0617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1693">
         <PDBx:U11>0.1454</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.1230</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.0574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1694">
         <PDBx:U11>0.1789</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.1608</PDBx:U22>
         <PDBx:U23>-0.0147</PDBx:U23>
         <PDBx:U33>0.0623</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1695">
         <PDBx:U11>0.1737</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.1576</PDBx:U22>
         <PDBx:U23>-0.0122</PDBx:U23>
         <PDBx:U33>0.0617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1696">
         <PDBx:U11>0.1836</PDBx:U11>
         <PDBx:U12>-0.0180</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.1698</PDBx:U22>
         <PDBx:U23>-0.0154</PDBx:U23>
         <PDBx:U33>0.0632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1697">
         <PDBx:U11>0.0825</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.0453</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1698">
         <PDBx:U11>0.0824</PDBx:U11>
         <PDBx:U12>-0.0180</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.0482</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.0387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1699">
         <PDBx:U11>0.1224</PDBx:U11>
         <PDBx:U12>-0.0212</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.0811</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.0444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1700">
         <PDBx:U11>0.1303</PDBx:U11>
         <PDBx:U12>-0.0253</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.0902</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.0410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1701">
         <PDBx:U11>0.0762</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.0467</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1702">
         <PDBx:U11>0.1500</PDBx:U11>
         <PDBx:U12>-0.0123</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.1265</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.0484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1703">
         <PDBx:U11>0.2468</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.2267</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.0879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1704">
         <PDBx:U11>0.1435</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.1260</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.0401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1705">
         <PDBx:U11>0.0643</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.0431</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.0383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1706">
         <PDBx:U11>0.0959</PDBx:U11>
         <PDBx:U12>-0.0199</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.0472</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1707">
         <PDBx:U11>0.1066</PDBx:U11>
         <PDBx:U12>-0.0232</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.0494</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1708">
         <PDBx:U11>0.1619</PDBx:U11>
         <PDBx:U12>-0.0267</PDBx:U12>
         <PDBx:U13>0.0098</PDBx:U13>
         <PDBx:U22>0.0976</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.0457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1709">
         <PDBx:U11>0.1428</PDBx:U11>
         <PDBx:U12>-0.0320</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.0744</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.0441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1710">
         <PDBx:U11>0.1480</PDBx:U11>
         <PDBx:U12>-0.0205</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.0846</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.0423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1711">
         <PDBx:U11>0.1460</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.0892</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.0460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1712">
         <PDBx:U11>0.1316</PDBx:U11>
         <PDBx:U12>-0.0245</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.0575</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.0384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1713">
         <PDBx:U11>0.1497</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.0898</PDBx:U22>
         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.0462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1714">
         <PDBx:U11>0.1164</PDBx:U11>
         <PDBx:U12>-0.0242</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.0496</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1715">
         <PDBx:U11>0.1261</PDBx:U11>
         <PDBx:U12>-0.0267</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.0515</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1716">
         <PDBx:U11>0.2013</PDBx:U11>
         <PDBx:U12>-0.0315</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.1309</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.0559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1717">
         <PDBx:U11>0.2132</PDBx:U11>
         <PDBx:U12>-0.0362</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>0.1348</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.0473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1718">
         <PDBx:U11>0.1240</PDBx:U11>
         <PDBx:U12>-0.0224</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.0494</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1719">
         <PDBx:U11>0.1847</PDBx:U11>
         <PDBx:U12>-0.0308</PDBx:U12>
         <PDBx:U13>0.0153</PDBx:U13>
         <PDBx:U22>0.1260</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.0564</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1720">
         <PDBx:U11>0.1898</PDBx:U11>
         <PDBx:U12>-0.0350</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>0.1368</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.0566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1721">
         <PDBx:U11>0.1980</PDBx:U11>
         <PDBx:U12>-0.0408</PDBx:U12>
         <PDBx:U13>0.0215</PDBx:U13>
         <PDBx:U22>0.1427</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.0506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1722">
         <PDBx:U11>0.2255</PDBx:U11>
         <PDBx:U12>-0.0461</PDBx:U12>
         <PDBx:U13>0.0274</PDBx:U13>
         <PDBx:U22>0.1697</PDBx:U22>
         <PDBx:U23>-0.0163</PDBx:U23>
         <PDBx:U33>0.0495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1723">
         <PDBx:U11>0.1778</PDBx:U11>
         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.1374</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0564</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1724">
         <PDBx:U11>0.2262</PDBx:U11>
         <PDBx:U12>-0.0280</PDBx:U12>
         <PDBx:U13>0.0234</PDBx:U13>
         <PDBx:U22>0.1896</PDBx:U22>
         <PDBx:U23>-0.0154</PDBx:U23>
         <PDBx:U33>0.0704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1725">
         <PDBx:U11>0.3002</PDBx:U11>
         <PDBx:U12>-0.0252</PDBx:U12>
         <PDBx:U13>0.0260</PDBx:U13>
         <PDBx:U22>0.2743</PDBx:U22>
         <PDBx:U23>-0.0193</PDBx:U23>
         <PDBx:U33>0.1322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1726">
         <PDBx:U11>0.2248</PDBx:U11>
         <PDBx:U12>-0.0282</PDBx:U12>
         <PDBx:U13>0.0270</PDBx:U13>
         <PDBx:U22>0.2056</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.0676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1727">
         <PDBx:U11>0.3742</PDBx:U11>
         <PDBx:U12>-0.0294</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.3591</PDBx:U22>
         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.2088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1728">
         <PDBx:U11>0.2239</PDBx:U11>
         <PDBx:U12>-0.0285</PDBx:U12>
         <PDBx:U13>0.0295</PDBx:U13>
         <PDBx:U22>0.2066</PDBx:U22>
         <PDBx:U23>-0.0251</PDBx:U23>
         <PDBx:U33>0.0656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1729">
         <PDBx:U11>0.1915</PDBx:U11>
         <PDBx:U12>-0.0327</PDBx:U12>
         <PDBx:U13>0.0271</PDBx:U13>
         <PDBx:U22>0.1833</PDBx:U22>
         <PDBx:U23>-0.0259</PDBx:U23>
         <PDBx:U33>0.0611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1730">
         <PDBx:U11>0.1638</PDBx:U11>
         <PDBx:U12>-0.0403</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>0.1074</PDBx:U22>
         <PDBx:U23>-0.0088</PDBx:U23>
         <PDBx:U33>0.0438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1731">
         <PDBx:U11>0.1660</PDBx:U11>
         <PDBx:U12>-0.0459</PDBx:U12>
         <PDBx:U13>0.0180</PDBx:U13>
         <PDBx:U22>0.1082</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.0417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1732">
         <PDBx:U11>0.2307</PDBx:U11>
         <PDBx:U12>-0.0497</PDBx:U12>
         <PDBx:U13>0.0230</PDBx:U13>
         <PDBx:U22>0.1589</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.0440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1733">
         <PDBx:U11>0.1975</PDBx:U11>
         <PDBx:U12>-0.0553</PDBx:U12>
         <PDBx:U13>0.0200</PDBx:U13>
         <PDBx:U22>0.1223</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.0414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1734">
         <PDBx:U11>0.1765</PDBx:U11>
         <PDBx:U12>-0.0431</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.1258</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.0415</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1735">
         <PDBx:U11>0.1110</PDBx:U11>
         <PDBx:U12>-0.0400</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.0728</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.0403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1736">
         <PDBx:U11>0.1702</PDBx:U11>
         <PDBx:U12>-0.0438</PDBx:U12>
         <PDBx:U13>0.0227</PDBx:U13>
         <PDBx:U22>0.1402</PDBx:U22>
         <PDBx:U23>-0.0171</PDBx:U23>
         <PDBx:U33>0.0436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1737">
         <PDBx:U11>0.1929</PDBx:U11>
         <PDBx:U12>-0.0479</PDBx:U12>
         <PDBx:U13>0.0253</PDBx:U13>
         <PDBx:U22>0.1668</PDBx:U22>
         <PDBx:U23>-0.0203</PDBx:U23>
         <PDBx:U33>0.0583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1738">
         <PDBx:U11>0.3325</PDBx:U11>
         <PDBx:U12>-0.0521</PDBx:U12>
         <PDBx:U13>0.0366</PDBx:U13>
         <PDBx:U22>0.3129</PDBx:U22>
         <PDBx:U23>-0.0328</PDBx:U23>
         <PDBx:U33>0.1436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1739">
         <PDBx:U11>0.1992</PDBx:U11>
         <PDBx:U12>-0.0550</PDBx:U12>
         <PDBx:U13>0.0326</PDBx:U13>
         <PDBx:U22>0.1823</PDBx:U22>
         <PDBx:U23>-0.0299</PDBx:U23>
         <PDBx:U33>0.0511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1740">
         <PDBx:U11>0.3644</PDBx:U11>
         <PDBx:U12>-0.0556</PDBx:U12>
         <PDBx:U13>0.0381</PDBx:U13>
         <PDBx:U22>0.3489</PDBx:U22>
         <PDBx:U23>-0.0360</PDBx:U23>
         <PDBx:U33>0.1748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1741">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0474</PDBx:U12>
         <PDBx:U13>0.0230</PDBx:U13>
         <PDBx:U22>0.1902</PDBx:U22>
         <PDBx:U23>-0.0086</PDBx:U23>
         <PDBx:U33>0.0578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1742">
         <PDBx:U11>0.3091</PDBx:U11>
         <PDBx:U12>-0.0513</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.2126</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.0787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1743">
         <PDBx:U11>0.3838</PDBx:U11>
         <PDBx:U12>-0.0588</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>0.2826</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.1453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1744">
         <PDBx:U11>0.3742</PDBx:U11>
         <PDBx:U12>-0.0582</PDBx:U12>
         <PDBx:U13>0.0268</PDBx:U13>
         <PDBx:U22>0.2762</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.1396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1745">
         <PDBx:U11>0.3199</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.2146</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.0904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1746">
         <PDBx:U11>0.3926</PDBx:U11>
         <PDBx:U12>-0.0497</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.2660</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.1473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1747">
         <PDBx:U11>0.3858</PDBx:U11>
         <PDBx:U12>-0.0663</PDBx:U12>
         <PDBx:U13>0.0264</PDBx:U13>
         <PDBx:U22>0.2778</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.1358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1748">
         <PDBx:U11>0.3932</PDBx:U11>
         <PDBx:U12>-0.0751</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.2806</PDBx:U22>
         <PDBx:U23>-0.0111</PDBx:U23>
         <PDBx:U33>0.1336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1749">
         <PDBx:U11>0.4553</PDBx:U11>
         <PDBx:U12>-0.0790</PDBx:U12>
         <PDBx:U13>0.0273</PDBx:U13>
         <PDBx:U22>0.3224</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.1808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1750">
         <PDBx:U11>0.4713</PDBx:U11>
         <PDBx:U12>-0.0807</PDBx:U12>
         <PDBx:U13>0.0239</PDBx:U13>
         <PDBx:U22>0.3273</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.1874</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1751">
         <PDBx:U11>0.4319</PDBx:U11>
         <PDBx:U12>-0.0821</PDBx:U12>
         <PDBx:U13>0.0349</PDBx:U13>
         <PDBx:U22>0.3263</PDBx:U22>
         <PDBx:U23>-0.0150</PDBx:U23>
         <PDBx:U33>0.1694</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1752">
         <PDBx:U11>0.5717</PDBx:U11>
         <PDBx:U12>-0.0881</PDBx:U12>
         <PDBx:U13>0.0405</PDBx:U13>
         <PDBx:U22>0.4729</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.3092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1753">
         <PDBx:U11>0.4277</PDBx:U11>
         <PDBx:U12>-0.0794</PDBx:U12>
         <PDBx:U13>0.0277</PDBx:U13>
         <PDBx:U22>0.2898</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.1519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1754">
         <PDBx:U11>0.4452</PDBx:U11>
         <PDBx:U12>-0.0830</PDBx:U12>
         <PDBx:U13>0.0248</PDBx:U13>
         <PDBx:U22>0.2875</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.1555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1755">
         <PDBx:U11>0.5089</PDBx:U11>
         <PDBx:U12>-0.0914</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.3512</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.2132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1756">
         <PDBx:U11>0.4970</PDBx:U11>
         <PDBx:U12>-0.0889</PDBx:U12>
         <PDBx:U13>0.0334</PDBx:U13>
         <PDBx:U22>0.3495</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.2110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1757">
         <PDBx:U11>0.4786</PDBx:U11>
         <PDBx:U12>-0.0746</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.3145</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.1942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1758">
         <PDBx:U11>0.4699</PDBx:U11>
         <PDBx:U12>-0.0661</PDBx:U12>
         <PDBx:U13>0.0138</PDBx:U13>
         <PDBx:U22>0.3083</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.1935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1759">
         <PDBx:U11>0.5068</PDBx:U11>
         <PDBx:U12>-0.0785</PDBx:U12>
         <PDBx:U13>0.0156</PDBx:U13>
         <PDBx:U22>0.3210</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.2074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1760">
         <PDBx:U11>0.5615</PDBx:U11>
         <PDBx:U12>-0.0575</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.4063</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.2983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1761">
         <PDBx:U11>0.4715</PDBx:U11>
         <PDBx:U12>-0.1014</PDBx:U12>
         <PDBx:U13>0.0322</PDBx:U13>
         <PDBx:U22>0.3023</PDBx:U22>
         <PDBx:U23>-0.0088</PDBx:U23>
         <PDBx:U33>0.1594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1762">
         <PDBx:U11>0.4774</PDBx:U11>
         <PDBx:U12>-0.1111</PDBx:U12>
         <PDBx:U13>0.0383</PDBx:U13>
         <PDBx:U22>0.3073</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.1574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1763">
         <PDBx:U11>0.5059</PDBx:U11>
         <PDBx:U12>-0.1126</PDBx:U12>
         <PDBx:U13>0.0450</PDBx:U13>
         <PDBx:U22>0.3577</PDBx:U22>
         <PDBx:U23>-0.0203</PDBx:U23>
         <PDBx:U33>0.1978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1764">
         <PDBx:U11>0.4853</PDBx:U11>
         <PDBx:U12>-0.1148</PDBx:U12>
         <PDBx:U13>0.0493</PDBx:U13>
         <PDBx:U22>0.3437</PDBx:U22>
         <PDBx:U23>-0.0248</PDBx:U23>
         <PDBx:U33>0.1807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1765">
         <PDBx:U11>0.4573</PDBx:U11>
         <PDBx:U12>-0.1103</PDBx:U12>
         <PDBx:U13>0.0453</PDBx:U13>
         <PDBx:U22>0.3204</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.1562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1766">
         <PDBx:U11>0.4358</PDBx:U11>
         <PDBx:U12>-0.1103</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.3199</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.1472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1767">
         <PDBx:U11>0.4436</PDBx:U11>
         <PDBx:U12>-0.1019</PDBx:U12>
         <PDBx:U13>0.0506</PDBx:U13>
         <PDBx:U22>0.3418</PDBx:U22>
         <PDBx:U23>-0.0302</PDBx:U23>
         <PDBx:U33>0.1716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1768">
         <PDBx:U11>0.4298</PDBx:U11>
         <PDBx:U12>-0.1024</PDBx:U12>
         <PDBx:U13>0.0547</PDBx:U13>
         <PDBx:U22>0.3441</PDBx:U22>
         <PDBx:U23>-0.0365</PDBx:U23>
         <PDBx:U33>0.1671</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1769">
         <PDBx:U11>0.3509</PDBx:U11>
         <PDBx:U12>-0.0942</PDBx:U12>
         <PDBx:U13>0.0459</PDBx:U13>
         <PDBx:U22>0.2430</PDBx:U22>
         <PDBx:U23>-0.0255</PDBx:U23>
         <PDBx:U33>0.0825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1770">
         <PDBx:U11>0.3423</PDBx:U11>
         <PDBx:U12>-0.0865</PDBx:U12>
         <PDBx:U13>0.0457</PDBx:U13>
         <PDBx:U22>0.2455</PDBx:U22>
         <PDBx:U23>-0.0269</PDBx:U23>
         <PDBx:U33>0.0880</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1771">
         <PDBx:U11>0.3844</PDBx:U11>
         <PDBx:U12>-0.0773</PDBx:U12>
         <PDBx:U13>0.0414</PDBx:U13>
         <PDBx:U22>0.2935</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.1404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1772">
         <PDBx:U11>0.3910</PDBx:U11>
         <PDBx:U12>-0.0743</PDBx:U12>
         <PDBx:U13>0.0367</PDBx:U13>
         <PDBx:U22>0.2898</PDBx:U22>
         <PDBx:U23>-0.0185</PDBx:U23>
         <PDBx:U33>0.1430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1773">
         <PDBx:U11>0.3905</PDBx:U11>
         <PDBx:U12>-0.0859</PDBx:U12>
         <PDBx:U13>0.0446</PDBx:U13>
         <PDBx:U22>0.2837</PDBx:U22>
         <PDBx:U23>-0.0253</PDBx:U23>
         <PDBx:U33>0.1329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1774">
         <PDBx:U11>0.4185</PDBx:U11>
         <PDBx:U12>-0.0959</PDBx:U12>
         <PDBx:U13>0.0496</PDBx:U13>
         <PDBx:U22>0.3067</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.1506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1775">
         <PDBx:U11>0.3800</PDBx:U11>
         <PDBx:U12>-0.0775</PDBx:U12>
         <PDBx:U13>0.0436</PDBx:U13>
         <PDBx:U22>0.2835</PDBx:U22>
         <PDBx:U23>-0.0260</PDBx:U23>
         <PDBx:U33>0.1368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1776">
         <PDBx:U11>0.5163</PDBx:U11>
         <PDBx:U12>-0.1000</PDBx:U12>
         <PDBx:U13>0.0560</PDBx:U13>
         <PDBx:U22>0.4217</PDBx:U22>
         <PDBx:U23>-0.0370</PDBx:U23>
         <PDBx:U33>0.2552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1777">
         <PDBx:U11>0.3243</PDBx:U11>
         <PDBx:U12>-0.0731</PDBx:U12>
         <PDBx:U13>0.0429</PDBx:U13>
         <PDBx:U22>0.2497</PDBx:U22>
         <PDBx:U23>-0.0273</PDBx:U23>
         <PDBx:U33>0.0929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1778">
         <PDBx:U11>0.2959</PDBx:U11>
         <PDBx:U12>-0.0650</PDBx:U12>
         <PDBx:U13>0.0396</PDBx:U13>
         <PDBx:U22>0.2285</PDBx:U22>
         <PDBx:U23>-0.0251</PDBx:U23>
         <PDBx:U33>0.0746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1779">
         <PDBx:U11>0.3479</PDBx:U11>
         <PDBx:U12>-0.0614</PDBx:U12>
         <PDBx:U13>0.0415</PDBx:U13>
         <PDBx:U22>0.2966</PDBx:U22>
         <PDBx:U23>-0.0297</PDBx:U23>
         <PDBx:U33>0.1389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1780">
         <PDBx:U11>0.3443</PDBx:U11>
         <PDBx:U12>-0.0654</PDBx:U12>
         <PDBx:U13>0.0454</PDBx:U13>
         <PDBx:U22>0.2998</PDBx:U22>
         <PDBx:U23>-0.0350</PDBx:U23>
         <PDBx:U33>0.1364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1781">
         <PDBx:U11>0.3002</PDBx:U11>
         <PDBx:U12>-0.0660</PDBx:U12>
         <PDBx:U13>0.0384</PDBx:U13>
         <PDBx:U22>0.2321</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.0759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1782">
         <PDBx:U11>0.3429</PDBx:U11>
         <PDBx:U12>-0.0716</PDBx:U12>
         <PDBx:U13>0.0427</PDBx:U13>
         <PDBx:U22>0.2841</PDBx:U22>
         <PDBx:U23>-0.0293</PDBx:U23>
         <PDBx:U33>0.1189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1783">
         <PDBx:U11>0.3805</PDBx:U11>
         <PDBx:U12>-0.0810</PDBx:U12>
         <PDBx:U13>0.0459</PDBx:U13>
         <PDBx:U22>0.3154</PDBx:U22>
         <PDBx:U23>-0.0312</PDBx:U23>
         <PDBx:U33>0.1451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1784">
         <PDBx:U11>0.3655</PDBx:U11>
         <PDBx:U12>-0.0692</PDBx:U12>
         <PDBx:U13>0.0441</PDBx:U13>
         <PDBx:U22>0.3217</PDBx:U22>
         <PDBx:U23>-0.0339</PDBx:U23>
         <PDBx:U33>0.1518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1785">
         <PDBx:U11>0.3806</PDBx:U11>
         <PDBx:U12>-0.0840</PDBx:U12>
         <PDBx:U13>0.0495</PDBx:U13>
         <PDBx:U22>0.3282</PDBx:U22>
         <PDBx:U23>-0.0375</PDBx:U23>
         <PDBx:U33>0.1500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1786">
         <PDBx:U11>0.3713</PDBx:U11>
         <PDBx:U12>-0.0767</PDBx:U12>
         <PDBx:U13>0.0483</PDBx:U13>
         <PDBx:U22>0.3318</PDBx:U22>
         <PDBx:U23>-0.0393</PDBx:U23>
         <PDBx:U33>0.1541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1787">
         <PDBx:U11>0.2952</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>0.0385</PDBx:U13>
         <PDBx:U22>0.2496</PDBx:U22>
         <PDBx:U23>-0.0278</PDBx:U23>
         <PDBx:U33>0.0949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1788">
         <PDBx:U11>0.2731</PDBx:U11>
         <PDBx:U12>-0.0505</PDBx:U12>
         <PDBx:U13>0.0393</PDBx:U13>
         <PDBx:U22>0.2410</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.0830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1789">
         <PDBx:U11>0.2914</PDBx:U11>
         <PDBx:U12>-0.0496</PDBx:U12>
         <PDBx:U13>0.0390</PDBx:U13>
         <PDBx:U22>0.2677</PDBx:U22>
         <PDBx:U23>-0.0336</PDBx:U23>
         <PDBx:U33>0.1055</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1790">
         <PDBx:U11>0.2940</PDBx:U11>
         <PDBx:U12>-0.0507</PDBx:U12>
         <PDBx:U13>0.0379</PDBx:U13>
         <PDBx:U22>0.2657</PDBx:U22>
         <PDBx:U23>-0.0312</PDBx:U23>
         <PDBx:U33>0.1039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1791">
         <PDBx:U11>0.2755</PDBx:U11>
         <PDBx:U12>-0.0437</PDBx:U12>
         <PDBx:U13>0.0364</PDBx:U13>
         <PDBx:U22>0.2441</PDBx:U22>
         <PDBx:U23>-0.0287</PDBx:U23>
         <PDBx:U33>0.0917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1792">
         <PDBx:U11>0.3169</PDBx:U11>
         <PDBx:U12>-0.0442</PDBx:U12>
         <PDBx:U13>0.0367</PDBx:U13>
         <PDBx:U22>0.2792</PDBx:U22>
         <PDBx:U23>-0.0277</PDBx:U23>
         <PDBx:U33>0.1311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1793">
         <PDBx:U11>0.5562</PDBx:U11>
         <PDBx:U12>-0.0464</PDBx:U12>
         <PDBx:U13>0.0353</PDBx:U13>
         <PDBx:U22>0.5039</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.3615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1794">
         <PDBx:U11>0.4722</PDBx:U11>
         <PDBx:U12>-0.0447</PDBx:U12>
         <PDBx:U13>0.0324</PDBx:U13>
         <PDBx:U22>0.4139</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.2748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1795">
         <PDBx:U11>0.4296</PDBx:U11>
         <PDBx:U12>-0.0497</PDBx:U12>
         <PDBx:U13>0.0369</PDBx:U13>
         <PDBx:U22>0.3715</PDBx:U22>
         <PDBx:U23>-0.0250</PDBx:U23>
         <PDBx:U33>0.2304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1796">
         <PDBx:U11>0.2445</PDBx:U11>
         <PDBx:U12>-0.0476</PDBx:U12>
         <PDBx:U13>0.0395</PDBx:U13>
         <PDBx:U22>0.2327</PDBx:U22>
         <PDBx:U23>-0.0380</PDBx:U23>
         <PDBx:U33>0.0677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1797">
         <PDBx:U11>0.2413</PDBx:U11>
         <PDBx:U12>-0.0460</PDBx:U12>
         <PDBx:U13>0.0382</PDBx:U13>
         <PDBx:U22>0.2378</PDBx:U22>
         <PDBx:U23>-0.0400</PDBx:U23>
         <PDBx:U33>0.0724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1798">
         <PDBx:U11>0.2459</PDBx:U11>
         <PDBx:U12>-0.0393</PDBx:U12>
         <PDBx:U13>0.0346</PDBx:U13>
         <PDBx:U22>0.2411</PDBx:U22>
         <PDBx:U23>-0.0359</PDBx:U23>
         <PDBx:U33>0.0765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1799">
         <PDBx:U11>0.2200</PDBx:U11>
         <PDBx:U12>-0.0356</PDBx:U12>
         <PDBx:U13>0.0322</PDBx:U13>
         <PDBx:U22>0.2124</PDBx:U22>
         <PDBx:U23>-0.0319</PDBx:U23>
         <PDBx:U33>0.0558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1800">
         <PDBx:U11>0.2728</PDBx:U11>
         <PDBx:U12>-0.0452</PDBx:U12>
         <PDBx:U13>0.0400</PDBx:U13>
         <PDBx:U22>0.2820</PDBx:U22>
         <PDBx:U23>-0.0476</PDBx:U23>
         <PDBx:U33>0.1077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1801">
         <PDBx:U11>0.5415</PDBx:U11>
         <PDBx:U12>-0.0393</PDBx:U12>
         <PDBx:U13>0.0374</PDBx:U13>
         <PDBx:U22>0.5551</PDBx:U22>
         <PDBx:U23>-0.0471</PDBx:U23>
         <PDBx:U33>0.3830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1802">
         <PDBx:U11>0.5591</PDBx:U11>
         <PDBx:U12>-0.0380</PDBx:U12>
         <PDBx:U13>0.0369</PDBx:U13>
         <PDBx:U22>0.5667</PDBx:U22>
         <PDBx:U23>-0.0432</PDBx:U23>
         <PDBx:U33>0.3985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1803">
         <PDBx:U11>0.6970</PDBx:U11>
         <PDBx:U12>-0.0363</PDBx:U12>
         <PDBx:U13>0.0359</PDBx:U13>
         <PDBx:U22>0.7199</PDBx:U22>
         <PDBx:U23>-0.0512</PDBx:U23>
         <PDBx:U33>0.5454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1804">
         <PDBx:U11>0.1809</PDBx:U11>
         <PDBx:U12>-0.0394</PDBx:U12>
         <PDBx:U13>0.0261</PDBx:U13>
         <PDBx:U22>0.1786</PDBx:U22>
         <PDBx:U23>-0.0276</PDBx:U23>
         <PDBx:U33>0.0596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1805">
         <PDBx:U11>0.1613</PDBx:U11>
         <PDBx:U12>-0.0337</PDBx:U12>
         <PDBx:U13>0.0206</PDBx:U13>
         <PDBx:U22>0.1577</PDBx:U22>
         <PDBx:U23>-0.0213</PDBx:U23>
         <PDBx:U33>0.0585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1806">
         <PDBx:U11>0.1681</PDBx:U11>
         <PDBx:U12>-0.0285</PDBx:U12>
         <PDBx:U13>0.0203</PDBx:U13>
         <PDBx:U22>0.1706</PDBx:U22>
         <PDBx:U23>-0.0234</PDBx:U23>
         <PDBx:U33>0.0612</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1807">
         <PDBx:U11>0.1356</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>0.0180</PDBx:U13>
         <PDBx:U22>0.1471</PDBx:U22>
         <PDBx:U23>-0.0235</PDBx:U23>
         <PDBx:U33>0.0515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1808">
         <PDBx:U11>0.1775</PDBx:U11>
         <PDBx:U12>-0.0326</PDBx:U12>
         <PDBx:U13>0.0219</PDBx:U13>
         <PDBx:U22>0.1755</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.0597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1809">
         <PDBx:U11>0.1529</PDBx:U11>
         <PDBx:U12>-0.0270</PDBx:U12>
         <PDBx:U13>0.0160</PDBx:U13>
         <PDBx:U22>0.1501</PDBx:U22>
         <PDBx:U23>-0.0170</PDBx:U23>
         <PDBx:U33>0.0605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1810">
         <PDBx:U11>0.1566</PDBx:U11>
         <PDBx:U12>-0.0255</PDBx:U12>
         <PDBx:U13>0.0148</PDBx:U13>
         <PDBx:U22>0.1453</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.0612</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1811">
         <PDBx:U11>0.1454</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0145</PDBx:U13>
         <PDBx:U22>0.1494</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.0572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1812">
         <PDBx:U11>0.1792</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>0.0149</PDBx:U13>
         <PDBx:U22>0.1674</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.0663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1813">
         <PDBx:U11>0.1521</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.1541</PDBx:U22>
         <PDBx:U23>-0.0165</PDBx:U23>
         <PDBx:U33>0.0568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1814">
         <PDBx:U11>0.2316</PDBx:U11>
         <PDBx:U12>-0.0163</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.2260</PDBx:U22>
         <PDBx:U23>-0.0201</PDBx:U23>
         <PDBx:U33>0.0746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1815">
         <PDBx:U11>0.1655</PDBx:U11>
         <PDBx:U12>-0.0131</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1590</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.0646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1816">
         <PDBx:U11>0.0958</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.0942</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.0498</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1817">
         <PDBx:U11>0.0956</PDBx:U11>
         <PDBx:U12>-0.0217</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.0987</PDBx:U22>
         <PDBx:U23>-0.0108</PDBx:U23>
         <PDBx:U33>0.0502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1818">
         <PDBx:U11>0.1609</PDBx:U11>
         <PDBx:U12>-0.0169</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.1591</PDBx:U22>
         <PDBx:U23>-0.0162</PDBx:U23>
         <PDBx:U33>0.0582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1819">
         <PDBx:U11>0.1417</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0125</PDBx:U13>
         <PDBx:U22>0.1335</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1820">
         <PDBx:U11>0.1100</PDBx:U11>
         <PDBx:U12>-0.0225</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.1137</PDBx:U22>
         <PDBx:U23>-0.0134</PDBx:U23>
         <PDBx:U33>0.0531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1821">
         <PDBx:U11>0.2278</PDBx:U11>
         <PDBx:U12>-0.0235</PDBx:U12>
         <PDBx:U13>0.0273</PDBx:U13>
         <PDBx:U22>0.2364</PDBx:U22>
         <PDBx:U23>-0.0347</PDBx:U23>
         <PDBx:U33>0.0759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1822">
         <PDBx:U11>0.2384</PDBx:U11>
         <PDBx:U12>-0.0216</PDBx:U12>
         <PDBx:U13>0.0258</PDBx:U13>
         <PDBx:U22>0.2560</PDBx:U22>
         <PDBx:U23>-0.0394</PDBx:U23>
         <PDBx:U33>0.0917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1823">
         <PDBx:U11>0.2425</PDBx:U11>
         <PDBx:U12>-0.0175</PDBx:U12>
         <PDBx:U13>0.0223</PDBx:U13>
         <PDBx:U22>0.2618</PDBx:U22>
         <PDBx:U23>-0.0384</PDBx:U23>
         <PDBx:U33>0.0985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1824">
         <PDBx:U11>0.2451</PDBx:U11>
         <PDBx:U12>-0.0246</PDBx:U12>
         <PDBx:U13>0.0282</PDBx:U13>
         <PDBx:U22>0.2685</PDBx:U22>
         <PDBx:U23>-0.0451</PDBx:U23>
         <PDBx:U33>0.1001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1825">
         <PDBx:U11>0.1372</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.1391</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.0575</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1826">
         <PDBx:U11>0.1336</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.1320</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.0560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1827">
         <PDBx:U11>0.1452</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.1417</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1828">
         <PDBx:U11>0.1484</PDBx:U11>
         <PDBx:U12>-0.0120</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1478</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.0494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1829">
         <PDBx:U11>0.1361</PDBx:U11>
         <PDBx:U12>-0.0079</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.1378</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.0608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1830">
         <PDBx:U11>0.1966</PDBx:U11>
         <PDBx:U12>-0.0064</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.1979</PDBx:U22>
         <PDBx:U23>-0.0160</PDBx:U23>
         <PDBx:U33>0.0753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1831">
         <PDBx:U11>0.2146</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.2188</PDBx:U22>
         <PDBx:U23>-0.0197</PDBx:U23>
         <PDBx:U33>0.0787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1832">
         <PDBx:U11>0.2173</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.2134</PDBx:U22>
         <PDBx:U23>-0.0147</PDBx:U23>
         <PDBx:U33>0.0723</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1833">
         <PDBx:U11>0.1072</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.0997</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.0445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1834">
         <PDBx:U11>0.1049</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.0968</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.0449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1835">
         <PDBx:U11>0.1175</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1137</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.0478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1836">
         <PDBx:U11>0.0582</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.0559</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1837">
         <PDBx:U11>0.1322</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.1208</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.0493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1838">
         <PDBx:U11>0.1633</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.1520</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.0527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1839">
         <PDBx:U11>0.1082</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.0975</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1840">
         <PDBx:U11>0.0600</PDBx:U11>
         <PDBx:U12>-0.0118</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.0580</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1841">
         <PDBx:U11>0.0599</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.0618</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1842">
         <PDBx:U11>0.0970</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.1034</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
         <PDBx:U33>0.0460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1843">
         <PDBx:U11>0.0608</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.0700</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1844">
         <PDBx:U11>0.0628</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.0634</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.0388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1845">
         <PDBx:U11>0.0673</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.0653</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1846">
         <PDBx:U11>0.0772</PDBx:U11>
         <PDBx:U12>-0.0130</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.0762</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1847">
         <PDBx:U11>0.0698</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.0649</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1848">
         <PDBx:U11>0.0643</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.0619</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.0391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1849">
         <PDBx:U11>0.0593</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.0532</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1850">
         <PDBx:U11>0.0984</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.0937</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.0401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1851">
         <PDBx:U11>0.0608</PDBx:U11>
         <PDBx:U12>-0.0130</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.0558</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1852">
         <PDBx:U11>0.0771</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.0850</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.0399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1853">
         <PDBx:U11>0.0902</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1039</PDBx:U22>
         <PDBx:U23>-0.0119</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1854">
         <PDBx:U11>0.1557</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>0.0126</PDBx:U13>
         <PDBx:U22>0.1726</PDBx:U22>
         <PDBx:U23>-0.0248</PDBx:U23>
         <PDBx:U33>0.0473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1855">
         <PDBx:U11>0.1836</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.2049</PDBx:U22>
         <PDBx:U23>-0.0318</PDBx:U23>
         <PDBx:U33>0.0558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1856">
         <PDBx:U11>0.1025</PDBx:U11>
         <PDBx:U12>-0.0132</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.1166</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.0446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1857">
         <PDBx:U11>0.0872</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.1007</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.0433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1858">
         <PDBx:U11>0.0985</PDBx:U11>
         <PDBx:U12>-0.0183</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.1049</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.0419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1859">
         <PDBx:U11>0.0788</PDBx:U11>
         <PDBx:U12>-0.0198</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.0985</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1860">
         <PDBx:U11>0.1424</PDBx:U11>
         <PDBx:U12>-0.0209</PDBx:U12>
         <PDBx:U13>0.0169</PDBx:U13>
         <PDBx:U22>0.1464</PDBx:U22>
         <PDBx:U23>-0.0190</PDBx:U23>
         <PDBx:U33>0.0543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1861">
         <PDBx:U11>0.0893</PDBx:U11>
         <PDBx:U12>-0.0237</PDBx:U12>
         <PDBx:U13>0.0116</PDBx:U13>
         <PDBx:U22>0.1071</PDBx:U22>
         <PDBx:U23>-0.0165</PDBx:U23>
         <PDBx:U33>0.0466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1862">
         <PDBx:U11>0.1798</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.1886</PDBx:U22>
         <PDBx:U23>-0.0278</PDBx:U23>
         <PDBx:U33>0.0628</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1863">
         <PDBx:U11>0.2760</PDBx:U11>
         <PDBx:U12>-0.0252</PDBx:U12>
         <PDBx:U13>0.0312</PDBx:U13>
         <PDBx:U22>0.2819</PDBx:U22>
         <PDBx:U23>-0.0351</PDBx:U23>
         <PDBx:U33>0.1242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1864">
         <PDBx:U11>0.1114</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1272</PDBx:U22>
         <PDBx:U23>-0.0171</PDBx:U23>
         <PDBx:U33>0.0426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1865">
         <PDBx:U11>0.1085</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.1279</PDBx:U22>
         <PDBx:U23>-0.0185</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1866">
         <PDBx:U11>0.1797</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0165</PDBx:U13>
         <PDBx:U22>0.1979</PDBx:U22>
         <PDBx:U23>-0.0294</PDBx:U23>
         <PDBx:U33>0.0499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1867">
         <PDBx:U11>0.1949</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.2157</PDBx:U22>
         <PDBx:U23>-0.0345</PDBx:U23>
         <PDBx:U33>0.0499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1868">
         <PDBx:U11>0.1352</PDBx:U11>
         <PDBx:U12>-0.0181</PDBx:U12>
         <PDBx:U13>0.0159</PDBx:U13>
         <PDBx:U22>0.1508</PDBx:U22>
         <PDBx:U23>-0.0222</PDBx:U23>
         <PDBx:U33>0.0495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1869">
         <PDBx:U11>0.2053</PDBx:U11>
         <PDBx:U12>-0.0169</PDBx:U12>
         <PDBx:U13>0.0220</PDBx:U13>
         <PDBx:U22>0.2140</PDBx:U22>
         <PDBx:U23>-0.0263</PDBx:U23>
         <PDBx:U33>0.0773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1870">
         <PDBx:U11>0.2012</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0204</PDBx:U13>
         <PDBx:U22>0.2079</PDBx:U22>
         <PDBx:U23>-0.0244</PDBx:U23>
         <PDBx:U33>0.0688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1871">
         <PDBx:U11>0.2432</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>0.0271</PDBx:U13>
         <PDBx:U22>0.2486</PDBx:U22>
         <PDBx:U23>-0.0295</PDBx:U23>
         <PDBx:U33>0.0961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1872">
         <PDBx:U11>0.0991</PDBx:U11>
         <PDBx:U12>-0.0124</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.1154</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.0414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1873">
         <PDBx:U11>0.0901</PDBx:U11>
         <PDBx:U12>-0.0125</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.1056</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1874">
         <PDBx:U11>0.1486</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.1613</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.0583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1875">
         <PDBx:U11>0.1566</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1682</PDBx:U22>
         <PDBx:U23>-0.0181</PDBx:U23>
         <PDBx:U33>0.0524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1876">
         <PDBx:U11>0.0959</PDBx:U11>
         <PDBx:U12>-0.0142</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1075</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.0423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1877">
         <PDBx:U11>0.1517</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>0.0152</PDBx:U13>
         <PDBx:U22>0.1635</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.0464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1878">
         <PDBx:U11>0.1714</PDBx:U11>
         <PDBx:U12>-0.0159</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.1791</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.0527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1879">
         <PDBx:U11>0.1673</PDBx:U11>
         <PDBx:U12>-0.0171</PDBx:U12>
         <PDBx:U13>0.0178</PDBx:U13>
         <PDBx:U22>0.1821</PDBx:U22>
         <PDBx:U23>-0.0250</PDBx:U23>
         <PDBx:U33>0.0452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1880">
         <PDBx:U11>0.1262</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.1373</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.0499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1881">
         <PDBx:U11>0.1390</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.1467</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.0495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1882">
         <PDBx:U11>0.2119</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.2208</PDBx:U22>
         <PDBx:U23>-0.0255</PDBx:U23>
         <PDBx:U33>0.0609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1883">
         <PDBx:U11>0.1624</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1754</PDBx:U22>
         <PDBx:U23>-0.0219</PDBx:U23>
         <PDBx:U33>0.0483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1884">
         <PDBx:U11>0.1809</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1824</PDBx:U22>
         <PDBx:U23>-0.0162</PDBx:U23>
         <PDBx:U33>0.0501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1885">
         <PDBx:U11>0.1768</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1772</PDBx:U22>
         <PDBx:U23>-0.0150</PDBx:U23>
         <PDBx:U33>0.0467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1886">
         <PDBx:U11>0.1736</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1749</PDBx:U22>
         <PDBx:U23>-0.0149</PDBx:U23>
         <PDBx:U33>0.0508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1887">
         <PDBx:U11>0.2312</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.2382</PDBx:U22>
         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.0744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1888">
         <PDBx:U11>0.2221</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.2318</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.0710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1889">
         <PDBx:U11>0.2626</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.2693</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.1097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1890">
         <PDBx:U11>0.2068</PDBx:U11>
         <PDBx:U12>0.0022</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.2097</PDBx:U22>
         <PDBx:U23>-0.0197</PDBx:U23>
         <PDBx:U33>0.0742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1891">
         <PDBx:U11>0.2498</PDBx:U11>
         <PDBx:U12>0.0060</PDBx:U12>
         <PDBx:U13>-0.0151</PDBx:U13>
         <PDBx:U22>0.2563</PDBx:U22>
         <PDBx:U23>-0.0298</PDBx:U23>
         <PDBx:U33>0.0932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1892">
         <PDBx:U11>0.3297</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.3324</PDBx:U22>
         <PDBx:U23>-0.0272</PDBx:U23>
         <PDBx:U33>0.1669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1893">
         <PDBx:U11>0.2678</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>-0.0093</PDBx:U13>
         <PDBx:U22>0.2693</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.1042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1894">
         <PDBx:U11>0.2391</PDBx:U11>
         <PDBx:U12>0.0062</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.2489</PDBx:U22>
         <PDBx:U23>-0.0301</PDBx:U23>
         <PDBx:U33>0.0904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1895">
         <PDBx:U11>0.2385</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>-0.0098</PDBx:U13>
         <PDBx:U22>0.2459</PDBx:U22>
         <PDBx:U23>-0.0284</PDBx:U23>
         <PDBx:U33>0.0900</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1896">
         <PDBx:U11>0.2978</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>-0.0139</PDBx:U13>
         <PDBx:U22>0.2975</PDBx:U22>
         <PDBx:U23>-0.0244</PDBx:U23>
         <PDBx:U33>0.1430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1897">
         <PDBx:U11>0.2795</PDBx:U11>
         <PDBx:U12>0.0094</PDBx:U12>
         <PDBx:U13>-0.0181</PDBx:U13>
         <PDBx:U22>0.2761</PDBx:U22>
         <PDBx:U23>-0.0244</PDBx:U23>
         <PDBx:U33>0.1210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1898">
         <PDBx:U11>0.2712</PDBx:U11>
         <PDBx:U12>0.0093</PDBx:U12>
         <PDBx:U13>-0.0116</PDBx:U13>
         <PDBx:U22>0.2840</PDBx:U22>
         <PDBx:U23>-0.0335</PDBx:U23>
         <PDBx:U33>0.1287</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1899">
         <PDBx:U11>0.3852</PDBx:U11>
         <PDBx:U12>0.0072</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.4051</PDBx:U22>
         <PDBx:U23>-0.0376</PDBx:U23>
         <PDBx:U33>0.2475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1900">
         <PDBx:U11>0.2824</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.2783</PDBx:U22>
         <PDBx:U23>-0.0210</PDBx:U23>
         <PDBx:U33>0.1256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1901">
         <PDBx:U11>0.2791</PDBx:U11>
         <PDBx:U12>0.0075</PDBx:U12>
         <PDBx:U13>-0.0153</PDBx:U13>
         <PDBx:U22>0.2673</PDBx:U22>
         <PDBx:U23>-0.0171</PDBx:U23>
         <PDBx:U33>0.1156</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1902">
         <PDBx:U11>0.2911</PDBx:U11>
         <PDBx:U12>0.0054</PDBx:U12>
         <PDBx:U13>-0.0158</PDBx:U13>
         <PDBx:U22>0.2756</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.1214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1903">
         <PDBx:U11>0.2881</PDBx:U11>
         <PDBx:U12>0.0064</PDBx:U12>
         <PDBx:U13>-0.0207</PDBx:U13>
         <PDBx:U22>0.2679</PDBx:U22>
         <PDBx:U23>-0.0149</PDBx:U23>
         <PDBx:U33>0.1132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1904">
         <PDBx:U11>0.3219</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>-0.0211</PDBx:U13>
         <PDBx:U22>0.3071</PDBx:U22>
         <PDBx:U23>-0.0182</PDBx:U23>
         <PDBx:U33>0.1578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1905">
         <PDBx:U11>0.5104</PDBx:U11>
         <PDBx:U12>0.0106</PDBx:U12>
         <PDBx:U13>-0.0237</PDBx:U13>
         <PDBx:U22>0.4867</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.3385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1906">
         <PDBx:U11>0.5138</PDBx:U11>
         <PDBx:U12>0.0078</PDBx:U12>
         <PDBx:U13>-0.0198</PDBx:U13>
         <PDBx:U22>0.4884</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.3397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1907">
         <PDBx:U11>0.6435</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>-0.0297</PDBx:U13>
         <PDBx:U22>0.6142</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.4674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1908">
         <PDBx:U11>0.2368</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0106</PDBx:U13>
         <PDBx:U22>0.2235</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.0722</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1909">
         <PDBx:U11>0.2302</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>-0.0099</PDBx:U13>
         <PDBx:U22>0.2145</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.0713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1910">
         <PDBx:U11>0.2399</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>-0.0122</PDBx:U13>
         <PDBx:U22>0.2168</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.0612</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1911">
         <PDBx:U11>0.1893</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.1635</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.0501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1912">
         <PDBx:U11>0.2470</PDBx:U11>
         <PDBx:U12>-0.0026</PDBx:U12>
         <PDBx:U13>-0.0051</PDBx:U13>
         <PDBx:U22>0.2358</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.0767</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1913">
         <PDBx:U11>0.3022</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.2920</PDBx:U22>
         <PDBx:U23>-0.0130</PDBx:U23>
         <PDBx:U33>0.1357</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1914">
         <PDBx:U11>0.2424</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.2329</PDBx:U22>
         <PDBx:U23>-0.0144</PDBx:U23>
         <PDBx:U33>0.0781</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1915">
         <PDBx:U11>0.1913</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>-0.0101</PDBx:U13>
         <PDBx:U22>0.1647</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.0553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1916">
         <PDBx:U11>0.1851</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>-0.0098</PDBx:U13>
         <PDBx:U22>0.1509</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.0554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1917">
         <PDBx:U11>0.2316</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.2002</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.0629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1918">
         <PDBx:U11>0.2202</PDBx:U11>
         <PDBx:U12>-0.0123</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.1953</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.0643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1919">
         <PDBx:U11>0.2180</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>-0.0158</PDBx:U13>
         <PDBx:U22>0.1776</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.0568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1920">
         <PDBx:U11>0.3167</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.2800</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.1096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1921">
         <PDBx:U11>0.1736</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>-0.0051</PDBx:U13>
         <PDBx:U22>0.1371</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1922">
         <PDBx:U11>0.1465</PDBx:U11>
         <PDBx:U12>-0.0201</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1133</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.0426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1923">
         <PDBx:U11>0.1943</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1639</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1924">
         <PDBx:U11>0.1597</PDBx:U11>
         <PDBx:U12>-0.0238</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.1355</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.0389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1925">
         <PDBx:U11>0.1942</PDBx:U11>
         <PDBx:U12>-0.0246</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.1553</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.0464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1926">
         <PDBx:U11>0.2047</PDBx:U11>
         <PDBx:U12>-0.0297</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.1699</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.0483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1927">
         <PDBx:U11>0.1860</PDBx:U11>
         <PDBx:U12>-0.0222</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.1456</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.0484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1928">
         <PDBx:U11>0.1639</PDBx:U11>
         <PDBx:U12>-0.0232</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.1288</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.0393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1945">
         <PDBx:U11>0.3963</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>-0.0234</PDBx:U13>
         <PDBx:U22>0.3769</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.2074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1946">
         <PDBx:U11>0.0873</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.0741</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.0383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1947">
         <PDBx:U11>0.0956</PDBx:U11>
         <PDBx:U12>-0.0165</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.0855</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.0439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1948">
         <PDBx:U11>0.1555</PDBx:U11>
         <PDBx:U12>-0.0206</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1469</PDBx:U22>
         <PDBx:U23>-0.0093</PDBx:U23>
         <PDBx:U33>0.0436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1949">
         <PDBx:U11>0.1667</PDBx:U11>
         <PDBx:U12>-0.0208</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.1621</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1950">
         <PDBx:U11>0.1292</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.1165</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.0507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1951">
         <PDBx:U11>0.1676</PDBx:U11>
         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1546</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1952">
         <PDBx:U11>0.2108</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.2026</PDBx:U22>
         <PDBx:U23>-0.0119</PDBx:U23>
         <PDBx:U33>0.0541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1953">
         <PDBx:U11>0.1906</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1839</PDBx:U22>
         <PDBx:U23>-0.0102</PDBx:U23>
         <PDBx:U33>0.0626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1954">
         <PDBx:U11>0.1421</PDBx:U11>
         <PDBx:U12>-0.0243</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.1303</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1955">
         <PDBx:U11>0.1495</PDBx:U11>
         <PDBx:U12>-0.0292</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.1400</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.0426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1956">
         <PDBx:U11>0.2019</PDBx:U11>
         <PDBx:U12>-0.0300</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.1961</PDBx:U22>
         <PDBx:U23>-0.0154</PDBx:U23>
         <PDBx:U33>0.0515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1957">
         <PDBx:U11>0.1807</PDBx:U11>
         <PDBx:U12>-0.0314</PDBx:U12>
         <PDBx:U13>0.0144</PDBx:U13>
         <PDBx:U22>0.1795</PDBx:U22>
         <PDBx:U23>-0.0161</PDBx:U23>
         <PDBx:U33>0.0517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1958">
         <PDBx:U11>0.1223</PDBx:U11>
         <PDBx:U12>-0.0339</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1078</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.0391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1959">
         <PDBx:U11>0.3805</PDBx:U11>
         <PDBx:U12>-0.0392</PDBx:U12>
         <PDBx:U13>0.0163</PDBx:U13>
         <PDBx:U22>0.3686</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.1849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1960">
         <PDBx:U11>0.5727</PDBx:U11>
         <PDBx:U12>-0.0449</PDBx:U12>
         <PDBx:U13>0.0149</PDBx:U13>
         <PDBx:U22>0.5546</PDBx:U22>
         <PDBx:U23>-0.0169</PDBx:U23>
         <PDBx:U33>0.3644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1961">
         <PDBx:U11>0.6541</PDBx:U11>
         <PDBx:U12>-0.0449</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.6308</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.4379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1962">
         <PDBx:U11>0.7501</PDBx:U11>
         <PDBx:U12>-0.0473</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.7288</PDBx:U22>
         <PDBx:U23>-0.0164</PDBx:U23>
         <PDBx:U33>0.5324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1963">
         <PDBx:U11>0.6346</PDBx:U11>
         <PDBx:U12>-0.0502</PDBx:U12>
         <PDBx:U13>0.0162</PDBx:U13>
         <PDBx:U22>0.6204</PDBx:U22>
         <PDBx:U23>-0.0202</PDBx:U23>
         <PDBx:U33>0.4229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1964">
         <PDBx:U11>0.5300</PDBx:U11>
         <PDBx:U12>-0.0467</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.5037</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.3052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1965">
         <PDBx:U11>0.1608</PDBx:U11>
         <PDBx:U12>-0.0291</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.1534</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1966">
         <PDBx:U11>0.1492</PDBx:U11>
         <PDBx:U12>-0.0299</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1456</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1967">
         <PDBx:U11>0.1563</PDBx:U11>
         <PDBx:U12>-0.0278</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.1579</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.0412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1968">
         <PDBx:U11>0.1937</PDBx:U11>
         <PDBx:U12>-0.0298</PDBx:U12>
         <PDBx:U13>0.0169</PDBx:U13>
         <PDBx:U22>0.1987</PDBx:U22>
         <PDBx:U23>-0.0213</PDBx:U23>
         <PDBx:U33>0.0458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1969">
         <PDBx:U11>0.1811</PDBx:U11>
         <PDBx:U12>-0.0276</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1749</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.0404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1970">
         <PDBx:U11>0.2119</PDBx:U11>
         <PDBx:U12>-0.0311</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.1995</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.0459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1971">
         <PDBx:U11>0.3450</PDBx:U11>
         <PDBx:U12>-0.0284</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.3292</PDBx:U22>
         <PDBx:U23>-0.0164</PDBx:U23>
         <PDBx:U33>0.1403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1972">
         <PDBx:U11>0.5095</PDBx:U11>
         <PDBx:U12>-0.0324</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.4883</PDBx:U22>
         <PDBx:U23>-0.0157</PDBx:U23>
         <PDBx:U33>0.2935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1973">
         <PDBx:U11>0.6713</PDBx:U11>
         <PDBx:U12>-0.0360</PDBx:U12>
         <PDBx:U13>-0.0068</PDBx:U13>
         <PDBx:U22>0.6414</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.4444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1974">
         <PDBx:U11>0.0808</PDBx:U11>
         <PDBx:U12>-0.0243</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.0827</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.0392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1975">
         <PDBx:U11>0.0744</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.0794</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.0394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1976">
         <PDBx:U11>0.1279</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.1329</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.0417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1977">
         <PDBx:U11>0.1157</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>0.0130</PDBx:U13>
         <PDBx:U22>0.1232</PDBx:U22>
         <PDBx:U23>-0.0144</PDBx:U23>
         <PDBx:U33>0.0421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1978">
         <PDBx:U11>0.1071</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0080</PDBx:U13>
         <PDBx:U22>0.1112</PDBx:U22>
         <PDBx:U23>-0.0101</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1979">
         <PDBx:U11>0.0987</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.1035</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.0404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1980">
         <PDBx:U11>0.1088</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.1148</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1981">
         <PDBx:U11>0.0725</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.0753</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1982">
         <PDBx:U11>0.0701</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.0734</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.0397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1983">
         <PDBx:U11>0.1375</PDBx:U11>
         <PDBx:U12>-0.0254</PDBx:U12>
         <PDBx:U13>0.0164</PDBx:U13>
         <PDBx:U22>0.1436</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1984">
         <PDBx:U11>0.1329</PDBx:U11>
         <PDBx:U12>-0.0252</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.1413</PDBx:U22>
         <PDBx:U23>-0.0191</PDBx:U23>
         <PDBx:U33>0.0441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1985">
         <PDBx:U11>0.1109</PDBx:U11>
         <PDBx:U12>-0.0198</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1111</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.0407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1986">
         <PDBx:U11>0.1163</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.1171</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.0414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1987">
         <PDBx:U11>0.1031</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1014</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.0417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1988">
         <PDBx:U11>0.1272</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.1330</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.0460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1989">
         <PDBx:U11>0.1213</PDBx:U11>
         <PDBx:U12>-0.0342</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.1301</PDBx:U22>
         <PDBx:U23>-0.0172</PDBx:U23>
         <PDBx:U33>0.0429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1990">
         <PDBx:U11>0.1991</PDBx:U11>
         <PDBx:U12>-0.0364</PDBx:U12>
         <PDBx:U13>0.0264</PDBx:U13>
         <PDBx:U22>0.2109</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1991">
         <PDBx:U11>0.2085</PDBx:U11>
         <PDBx:U12>-0.0391</PDBx:U12>
         <PDBx:U13>0.0303</PDBx:U13>
         <PDBx:U22>0.2246</PDBx:U22>
         <PDBx:U23>-0.0342</PDBx:U23>
         <PDBx:U33>0.0603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1992">
         <PDBx:U11>0.1302</PDBx:U11>
         <PDBx:U12>-0.0372</PDBx:U12>
         <PDBx:U13>0.0152</PDBx:U13>
         <PDBx:U22>0.1357</PDBx:U22>
         <PDBx:U23>-0.0163</PDBx:U23>
         <PDBx:U33>0.0465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1993">
         <PDBx:U11>0.1753</PDBx:U11>
         <PDBx:U12>-0.0335</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.1782</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.0504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1994">
         <PDBx:U11>0.1461</PDBx:U11>
         <PDBx:U12>-0.0373</PDBx:U12>
         <PDBx:U13>0.0184</PDBx:U13>
         <PDBx:U22>0.1559</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.0447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1995">
         <PDBx:U11>0.1423</PDBx:U11>
         <PDBx:U12>-0.0411</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.1547</PDBx:U22>
         <PDBx:U23>-0.0216</PDBx:U23>
         <PDBx:U33>0.0442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1996">
         <PDBx:U11>0.1771</PDBx:U11>
         <PDBx:U12>-0.0381</PDBx:U12>
         <PDBx:U13>0.0252</PDBx:U13>
         <PDBx:U22>0.1928</PDBx:U22>
         <PDBx:U23>-0.0287</PDBx:U23>
         <PDBx:U33>0.0469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1997">
         <PDBx:U11>0.1361</PDBx:U11>
         <PDBx:U12>-0.0414</PDBx:U12>
         <PDBx:U13>0.0220</PDBx:U13>
         <PDBx:U22>0.1561</PDBx:U22>
         <PDBx:U23>-0.0259</PDBx:U23>
         <PDBx:U33>0.0463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1998">
         <PDBx:U11>0.1605</PDBx:U11>
         <PDBx:U12>-0.0423</PDBx:U12>
         <PDBx:U13>0.0180</PDBx:U13>
         <PDBx:U22>0.1687</PDBx:U22>
         <PDBx:U23>-0.0209</PDBx:U23>
         <PDBx:U33>0.0445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1999">
         <PDBx:U11>0.2495</PDBx:U11>
         <PDBx:U12>-0.0455</PDBx:U12>
         <PDBx:U13>0.0234</PDBx:U13>
         <PDBx:U22>0.2529</PDBx:U22>
         <PDBx:U23>-0.0274</PDBx:U23>
         <PDBx:U33>0.0624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2000">
         <PDBx:U11>0.4227</PDBx:U11>
         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.4212</PDBx:U22>
         <PDBx:U23>-0.0256</PDBx:U23>
         <PDBx:U33>0.2245</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2001">
         <PDBx:U11>0.3395</PDBx:U11>
         <PDBx:U12>-0.0519</PDBx:U12>
         <PDBx:U13>0.0216</PDBx:U13>
         <PDBx:U22>0.3406</PDBx:U22>
         <PDBx:U23>-0.0278</PDBx:U23>
         <PDBx:U33>0.1398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2002">
         <PDBx:U11>0.4249</PDBx:U11>
         <PDBx:U12>-0.0465</PDBx:U12>
         <PDBx:U13>0.0155</PDBx:U13>
         <PDBx:U22>0.4170</PDBx:U22>
         <PDBx:U23>-0.0221</PDBx:U23>
         <PDBx:U33>0.2200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2003">
         <PDBx:U11>0.1274</PDBx:U11>
         <PDBx:U12>-0.0347</PDBx:U12>
         <PDBx:U13>0.0171</PDBx:U13>
         <PDBx:U22>0.1415</PDBx:U22>
         <PDBx:U23>-0.0198</PDBx:U23>
         <PDBx:U33>0.0437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2004">
         <PDBx:U11>0.1258</PDBx:U11>
         <PDBx:U12>-0.0329</PDBx:U12>
         <PDBx:U13>0.0180</PDBx:U13>
         <PDBx:U22>0.1422</PDBx:U22>
         <PDBx:U23>-0.0210</PDBx:U23>
         <PDBx:U33>0.0451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2005">
         <PDBx:U11>0.1736</PDBx:U11>
         <PDBx:U12>-0.0299</PDBx:U12>
         <PDBx:U13>0.0246</PDBx:U13>
         <PDBx:U22>0.1897</PDBx:U22>
         <PDBx:U23>-0.0277</PDBx:U23>
         <PDBx:U33>0.0622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2006">
         <PDBx:U11>0.1781</PDBx:U11>
         <PDBx:U12>-0.0291</PDBx:U12>
         <PDBx:U13>0.0263</PDBx:U13>
         <PDBx:U22>0.1953</PDBx:U22>
         <PDBx:U23>-0.0297</PDBx:U23>
         <PDBx:U33>0.0683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2007">
         <PDBx:U11>0.1212</PDBx:U11>
         <PDBx:U12>-0.0299</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.1363</PDBx:U22>
         <PDBx:U23>-0.0188</PDBx:U23>
         <PDBx:U33>0.0435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2008">
         <PDBx:U11>0.1694</PDBx:U11>
         <PDBx:U12>-0.0296</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.1876</PDBx:U22>
         <PDBx:U23>-0.0282</PDBx:U23>
         <PDBx:U33>0.0470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2009">
         <PDBx:U11>0.2529</PDBx:U11>
         <PDBx:U12>-0.0266</PDBx:U12>
         <PDBx:U13>0.0265</PDBx:U13>
         <PDBx:U22>0.2712</PDBx:U22>
         <PDBx:U23>-0.0327</PDBx:U23>
         <PDBx:U33>0.1008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2010">
         <PDBx:U11>0.1756</PDBx:U11>
         <PDBx:U12>-0.0275</PDBx:U12>
         <PDBx:U13>0.0226</PDBx:U13>
         <PDBx:U22>0.1962</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.0656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2011">
         <PDBx:U11>0.0743</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.0919</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.0408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2012">
         <PDBx:U11>0.1144</PDBx:U11>
         <PDBx:U12>-0.0300</PDBx:U12>
         <PDBx:U13>0.0163</PDBx:U13>
         <PDBx:U22>0.1287</PDBx:U22>
         <PDBx:U23>-0.0188</PDBx:U23>
         <PDBx:U33>0.0491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2013">
         <PDBx:U11>0.0982</PDBx:U11>
         <PDBx:U12>-0.0282</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.1120</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.0445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2014">
         <PDBx:U11>0.1671</PDBx:U11>
         <PDBx:U12>-0.0230</PDBx:U12>
         <PDBx:U13>0.0245</PDBx:U13>
         <PDBx:U22>0.1778</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.0572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2015">
         <PDBx:U11>0.1992</PDBx:U11>
         <PDBx:U12>-0.0208</PDBx:U12>
         <PDBx:U13>0.0300</PDBx:U13>
         <PDBx:U22>0.2091</PDBx:U22>
         <PDBx:U23>-0.0339</PDBx:U23>
         <PDBx:U33>0.0673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2016">
         <PDBx:U11>0.1451</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>0.0248</PDBx:U13>
         <PDBx:U22>0.1630</PDBx:U22>
         <PDBx:U23>-0.0296</PDBx:U23>
         <PDBx:U33>0.0527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2017">
         <PDBx:U11>0.2190</PDBx:U11>
         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>0.0339</PDBx:U13>
         <PDBx:U22>0.2396</PDBx:U22>
         <PDBx:U23>-0.0401</PDBx:U23>
         <PDBx:U33>0.0816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2018">
         <PDBx:U11>0.3540</PDBx:U11>
         <PDBx:U12>-0.0349</PDBx:U12>
         <PDBx:U13>0.0370</PDBx:U13>
         <PDBx:U22>0.3801</PDBx:U22>
         <PDBx:U23>-0.0459</PDBx:U23>
         <PDBx:U33>0.2225</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2019">
         <PDBx:U11>0.4676</PDBx:U11>
         <PDBx:U12>-0.0405</PDBx:U12>
         <PDBx:U13>0.0387</PDBx:U13>
         <PDBx:U22>0.4967</PDBx:U22>
         <PDBx:U23>-0.0480</PDBx:U23>
         <PDBx:U33>0.3318</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2020">
         <PDBx:U11>0.4541</PDBx:U11>
         <PDBx:U12>-0.0401</PDBx:U12>
         <PDBx:U13>0.0376</PDBx:U13>
         <PDBx:U22>0.4815</PDBx:U22>
         <PDBx:U23>-0.0468</PDBx:U23>
         <PDBx:U33>0.3165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2021">
         <PDBx:U11>0.0891</PDBx:U11>
         <PDBx:U12>-0.0235</PDBx:U12>
         <PDBx:U13>0.0121</PDBx:U13>
         <PDBx:U22>0.0980</PDBx:U22>
         <PDBx:U23>-0.0136</PDBx:U23>
         <PDBx:U33>0.0424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2022">
         <PDBx:U11>0.0961</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>0.0128</PDBx:U13>
         <PDBx:U22>0.1022</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.0427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2023">
         <PDBx:U11>0.1568</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.1592</PDBx:U22>
         <PDBx:U23>-0.0195</PDBx:U23>
         <PDBx:U33>0.0561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2024">
         <PDBx:U11>0.1701</PDBx:U11>
         <PDBx:U12>-0.0168</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.1725</PDBx:U22>
         <PDBx:U23>-0.0197</PDBx:U23>
         <PDBx:U33>0.0586</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2025">
         <PDBx:U11>0.0922</PDBx:U11>
         <PDBx:U12>-0.0213</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.0994</PDBx:U22>
         <PDBx:U23>-0.0128</PDBx:U23>
         <PDBx:U33>0.0430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2026">
         <PDBx:U11>0.1366</PDBx:U11>
         <PDBx:U12>-0.0226</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.1476</PDBx:U22>
         <PDBx:U23>-0.0213</PDBx:U23>
         <PDBx:U33>0.0453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2027">
         <PDBx:U11>0.1446</PDBx:U11>
         <PDBx:U12>-0.0218</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.1571</PDBx:U22>
         <PDBx:U23>-0.0218</PDBx:U23>
         <PDBx:U33>0.0472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2028">
         <PDBx:U11>0.2128</PDBx:U11>
         <PDBx:U12>-0.0223</PDBx:U12>
         <PDBx:U13>0.0307</PDBx:U13>
         <PDBx:U22>0.2247</PDBx:U22>
         <PDBx:U23>-0.0327</PDBx:U23>
         <PDBx:U33>0.0733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2029">
         <PDBx:U11>0.0916</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.0904</PDBx:U22>
         <PDBx:U23>-0.0100</PDBx:U23>
         <PDBx:U33>0.0470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2030">
         <PDBx:U11>0.1097</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>0.0120</PDBx:U13>
         <PDBx:U22>0.1044</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.0461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2031">
         <PDBx:U11>0.1386</PDBx:U11>
         <PDBx:U12>-0.0141</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.1311</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.0433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2032">
         <PDBx:U11>0.1263</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.1202</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2033">
         <PDBx:U11>0.0660</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.0580</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.0398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2034">
         <PDBx:U11>0.0652</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.0612</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.0402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2035">
         <PDBx:U11>0.0727</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.0696</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.0405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2036">
         <PDBx:U11>0.1514</PDBx:U11>
         <PDBx:U12>-0.0130</PDBx:U12>
         <PDBx:U13>0.0177</PDBx:U13>
         <PDBx:U22>0.1512</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2037">
         <PDBx:U11>0.2511</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>0.0244</PDBx:U13>
         <PDBx:U22>0.2549</PDBx:U22>
         <PDBx:U23>-0.0286</PDBx:U23>
         <PDBx:U33>0.1189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2038">
         <PDBx:U11>0.1128</PDBx:U11>
         <PDBx:U12>-0.0188</PDBx:U12>
         <PDBx:U13>0.0145</PDBx:U13>
         <PDBx:U22>0.1178</PDBx:U22>
         <PDBx:U23>-0.0161</PDBx:U23>
         <PDBx:U33>0.0434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2039">
         <PDBx:U11>0.1047</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.1129</PDBx:U22>
         <PDBx:U23>-0.0178</PDBx:U23>
         <PDBx:U33>0.0442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2040">
         <PDBx:U11>0.0965</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.0855</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.0422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2041">
         <PDBx:U11>0.1088</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.0957</PDBx:U22>
         <PDBx:U23>-0.0088</PDBx:U23>
         <PDBx:U33>0.0461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2042">
         <PDBx:U11>0.1331</PDBx:U11>
         <PDBx:U12>-0.0159</PDBx:U12>
         <PDBx:U13>0.0153</PDBx:U13>
         <PDBx:U22>0.1163</PDBx:U22>
         <PDBx:U23>-0.0124</PDBx:U23>
         <PDBx:U33>0.0472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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      <PDBx:atom_site_anisotrop id="2059">
         <PDBx:U11>0.2266</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.0208</PDBx:U13>
         <PDBx:U22>0.1751</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.0706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2060">
         <PDBx:U11>0.2314</PDBx:U11>
         <PDBx:U12>-0.0127</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>0.1845</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.0795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2061">
         <PDBx:U11>0.2536</PDBx:U11>
         <PDBx:U12>-0.0165</PDBx:U12>
         <PDBx:U13>0.0180</PDBx:U13>
         <PDBx:U22>0.1890</PDBx:U22>
         <PDBx:U23>-0.0181</PDBx:U23>
         <PDBx:U33>0.0911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2062">
         <PDBx:U11>0.3377</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0196</PDBx:U13>
         <PDBx:U22>0.2987</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.1932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2063">
         <PDBx:U11>0.2999</PDBx:U11>
         <PDBx:U12>-0.0275</PDBx:U12>
         <PDBx:U13>0.0280</PDBx:U13>
         <PDBx:U22>0.2469</PDBx:U22>
         <PDBx:U23>-0.0215</PDBx:U23>
         <PDBx:U33>0.1295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2064">
         <PDBx:U11>0.3214</PDBx:U11>
         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>0.0306</PDBx:U13>
         <PDBx:U22>0.2641</PDBx:U22>
         <PDBx:U23>-0.0233</PDBx:U23>
         <PDBx:U33>0.1458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2065">
         <PDBx:U11>0.3916</PDBx:U11>
         <PDBx:U12>-0.0322</PDBx:U12>
         <PDBx:U13>0.0283</PDBx:U13>
         <PDBx:U22>0.3212</PDBx:U22>
         <PDBx:U23>-0.0219</PDBx:U23>
         <PDBx:U33>0.2117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2066">
         <PDBx:U11>0.3556</PDBx:U11>
         <PDBx:U12>-0.0305</PDBx:U12>
         <PDBx:U13>0.0246</PDBx:U13>
         <PDBx:U22>0.2769</PDBx:U22>
         <PDBx:U23>-0.0191</PDBx:U23>
         <PDBx:U33>0.1725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2067">
         <PDBx:U11>0.3416</PDBx:U11>
         <PDBx:U12>-0.0364</PDBx:U12>
         <PDBx:U13>0.0324</PDBx:U13>
         <PDBx:U22>0.2842</PDBx:U22>
         <PDBx:U23>-0.0234</PDBx:U23>
         <PDBx:U33>0.1599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2068">
         <PDBx:U11>0.3815</PDBx:U11>
         <PDBx:U12>-0.0339</PDBx:U12>
         <PDBx:U13>0.0298</PDBx:U13>
         <PDBx:U22>0.3243</PDBx:U22>
         <PDBx:U23>-0.0207</PDBx:U23>
         <PDBx:U33>0.2002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2069">
         <PDBx:U11>0.3119</PDBx:U11>
         <PDBx:U12>-0.0283</PDBx:U12>
         <PDBx:U13>0.0276</PDBx:U13>
         <PDBx:U22>0.2602</PDBx:U22>
         <PDBx:U23>-0.0200</PDBx:U23>
         <PDBx:U33>0.1386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2070">
         <PDBx:U11>0.3845</PDBx:U11>
         <PDBx:U12>-0.0336</PDBx:U12>
         <PDBx:U13>0.0299</PDBx:U13>
         <PDBx:U22>0.3126</PDBx:U22>
         <PDBx:U23>-0.0242</PDBx:U23>
         <PDBx:U33>0.2051</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2071">
         <PDBx:U11>0.4076</PDBx:U11>
         <PDBx:U12>-0.0332</PDBx:U12>
         <PDBx:U13>0.0274</PDBx:U13>
         <PDBx:U22>0.3233</PDBx:U22>
         <PDBx:U23>-0.0236</PDBx:U23>
         <PDBx:U33>0.2250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2072">
         <PDBx:U11>0.4673</PDBx:U11>
         <PDBx:U12>-0.0360</PDBx:U12>
         <PDBx:U13>0.0249</PDBx:U13>
         <PDBx:U22>0.3680</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.2733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2073">
         <PDBx:U11>0.4801</PDBx:U11>
         <PDBx:U12>-0.0332</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.3702</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.2844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2074">
         <PDBx:U11>0.4529</PDBx:U11>
         <PDBx:U12>-0.0355</PDBx:U12>
         <PDBx:U13>0.0304</PDBx:U13>
         <PDBx:U22>0.3692</PDBx:U22>
         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.2712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2075">
         <PDBx:U11>0.8834</PDBx:U11>
         <PDBx:U12>-0.0330</PDBx:U12>
         <PDBx:U13>0.0273</PDBx:U13>
         <PDBx:U22>0.7903</PDBx:U22>
         <PDBx:U23>-0.0272</PDBx:U23>
         <PDBx:U33>0.7028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2076">
         <PDBx:U11>0.8269</PDBx:U11>
         <PDBx:U12>-0.0278</PDBx:U12>
         <PDBx:U13>0.0239</PDBx:U13>
         <PDBx:U22>0.7348</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.6532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2077">
         <PDBx:U11>0.8123</PDBx:U11>
         <PDBx:U12>-0.0368</PDBx:U12>
         <PDBx:U13>0.0284</PDBx:U13>
         <PDBx:U22>0.7102</PDBx:U22>
         <PDBx:U23>-0.0281</PDBx:U23>
         <PDBx:U33>0.6254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2078">
         <PDBx:U11>0.4156</PDBx:U11>
         <PDBx:U12>-0.0415</PDBx:U12>
         <PDBx:U13>0.0276</PDBx:U13>
         <PDBx:U22>0.3158</PDBx:U22>
         <PDBx:U23>-0.0203</PDBx:U23>
         <PDBx:U33>0.2139</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2079">
         <PDBx:U11>0.4290</PDBx:U11>
         <PDBx:U12>-0.0458</PDBx:U12>
         <PDBx:U13>0.0260</PDBx:U13>
         <PDBx:U22>0.3155</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.2146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2080">
         <PDBx:U11>0.4677</PDBx:U11>
         <PDBx:U12>-0.0421</PDBx:U12>
         <PDBx:U13>0.0209</PDBx:U13>
         <PDBx:U22>0.3488</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.2521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2081">
         <PDBx:U11>0.4679</PDBx:U11>
         <PDBx:U12>-0.0454</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.3364</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.2413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2082">
         <PDBx:U11>0.4715</PDBx:U11>
         <PDBx:U12>-0.0529</PDBx:U12>
         <PDBx:U13>0.0309</PDBx:U13>
         <PDBx:U22>0.3621</PDBx:U22>
         <PDBx:U23>-0.0195</PDBx:U23>
         <PDBx:U33>0.2511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2083">
         <PDBx:U11>0.6289</PDBx:U11>
         <PDBx:U12>-0.0514</PDBx:U12>
         <PDBx:U13>0.0326</PDBx:U13>
         <PDBx:U22>0.5337</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.4150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2084">
         <PDBx:U11>0.7343</PDBx:U11>
         <PDBx:U12>-0.0581</PDBx:U12>
         <PDBx:U13>0.0355</PDBx:U13>
         <PDBx:U22>0.6389</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.5124</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2085">
         <PDBx:U11>0.8423</PDBx:U11>
         <PDBx:U12>-0.0558</PDBx:U12>
         <PDBx:U13>0.0348</PDBx:U13>
         <PDBx:U22>0.7550</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.6246</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2086">
         <PDBx:U11>1.0095</PDBx:U11>
         <PDBx:U12>-0.0544</PDBx:U12>
         <PDBx:U13>0.0313</PDBx:U13>
         <PDBx:U22>0.9153</PDBx:U22>
         <PDBx:U23>-0.0170</PDBx:U23>
         <PDBx:U33>0.7878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2087">
         <PDBx:U11>0.8489</PDBx:U11>
         <PDBx:U12>-0.0549</PDBx:U12>
         <PDBx:U13>0.0275</PDBx:U13>
         <PDBx:U22>0.7392</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.6189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2088">
         <PDBx:U11>0.7733</PDBx:U11>
         <PDBx:U12>-0.0525</PDBx:U12>
         <PDBx:U13>0.0310</PDBx:U13>
         <PDBx:U22>0.6873</PDBx:U22>
         <PDBx:U23>-0.0168</PDBx:U23>
         <PDBx:U33>0.5560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2089">
         <PDBx:U11>0.4069</PDBx:U11>
         <PDBx:U12>-0.0358</PDBx:U12>
         <PDBx:U13>0.0192</PDBx:U13>
         <PDBx:U22>0.2973</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.2018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2090">
         <PDBx:U11>0.4033</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0144</PDBx:U13>
         <PDBx:U22>0.2898</PDBx:U22>
         <PDBx:U23>-0.0108</PDBx:U23>
         <PDBx:U33>0.1984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2091">
         <PDBx:U11>0.5015</PDBx:U11>
         <PDBx:U12>-0.0282</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.3763</PDBx:U22>
         <PDBx:U23>-0.0099</PDBx:U23>
         <PDBx:U33>0.2962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0176</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0002</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U33>0.4697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0022</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2141">
         <PDBx:U11>0.3235</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.2112</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2142">
         <PDBx:U11>0.3241</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1979</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.1091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2143">
         <PDBx:U11>0.3611</PDBx:U11>
         <PDBx:U12>-0.0338</PDBx:U12>
         <PDBx:U13>0.0079</PDBx:U13>
         <PDBx:U22>0.2382</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.1402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2144">
         <PDBx:U11>0.3672</PDBx:U11>
         <PDBx:U12>-0.0407</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.2455</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2145">
         <PDBx:U11>0.3385</PDBx:U11>
         <PDBx:U12>-0.0307</PDBx:U12>
         <PDBx:U13>0.0098</PDBx:U13>
         <PDBx:U22>0.2307</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2146">
         <PDBx:U11>0.3326</PDBx:U11>
         <PDBx:U12>-0.0149</PDBx:U12>
         <PDBx:U13>-0.0073</PDBx:U13>
         <PDBx:U22>0.1947</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.1301</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2147">
         <PDBx:U11>0.3067</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>-0.0092</PDBx:U13>
         <PDBx:U22>0.1726</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.1151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2148">
         <PDBx:U11>0.2823</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>-0.0122</PDBx:U13>
         <PDBx:U22>0.1555</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.1002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2149">
         <PDBx:U11>0.2774</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>-0.0101</PDBx:U13>
         <PDBx:U22>0.1628</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.1065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2150">
         <PDBx:U11>0.3625</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>-0.0146</PDBx:U13>
         <PDBx:U22>0.2124</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.1659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2151">
         <PDBx:U11>0.4881</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>-0.0117</PDBx:U13>
         <PDBx:U22>0.3347</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
         <PDBx:U33>0.2891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2152">
         <PDBx:U11>0.6596</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>-0.0176</PDBx:U13>
         <PDBx:U22>0.4936</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.4606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2153">
         <PDBx:U11>0.7369</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>-0.0250</PDBx:U13>
         <PDBx:U22>0.5529</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.5273</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2154">
         <PDBx:U11>0.9320</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>-0.0265</PDBx:U13>
         <PDBx:U22>0.7310</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.7068</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2155">
         <PDBx:U11>0.8093</PDBx:U11>
         <PDBx:U12>-0.0192</PDBx:U12>
         <PDBx:U13>-0.0206</PDBx:U13>
         <PDBx:U22>0.6079</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.5777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2156">
         <PDBx:U11>0.7633</PDBx:U11>
         <PDBx:U12>-0.0115</PDBx:U12>
         <PDBx:U13>-0.0340</PDBx:U13>
         <PDBx:U22>0.5454</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.5282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2157">
         <PDBx:U11>0.2529</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>-0.0171</PDBx:U13>
         <PDBx:U22>0.1183</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.0659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2158">
         <PDBx:U11>0.2495</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>-0.0203</PDBx:U13>
         <PDBx:U22>0.1210</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.0705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2159">
         <PDBx:U11>0.2923</PDBx:U11>
         <PDBx:U12>0.0021</PDBx:U12>
         <PDBx:U13>-0.0147</PDBx:U13>
         <PDBx:U22>0.1798</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2160">
         <PDBx:U11>0.2549</PDBx:U11>
         <PDBx:U12>0.0055</PDBx:U12>
         <PDBx:U13>-0.0139</PDBx:U13>
         <PDBx:U22>0.1532</PDBx:U22>
         <PDBx:U23>-0.0100</PDBx:U23>
         <PDBx:U33>0.0929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2161">
         <PDBx:U11>0.3054</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>-0.0267</PDBx:U13>
         <PDBx:U22>0.1644</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2162">
         <PDBx:U11>0.2919</PDBx:U11>
         <PDBx:U12>0.0087</PDBx:U12>
         <PDBx:U13>-0.0289</PDBx:U13>
         <PDBx:U22>0.1591</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2163">
         <PDBx:U11>0.3154</PDBx:U11>
         <PDBx:U12>0.0064</PDBx:U12>
         <PDBx:U13>-0.0336</PDBx:U13>
         <PDBx:U22>0.1583</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.1234</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2164">
         <PDBx:U11>0.2473</PDBx:U11>
         <PDBx:U12>-0.0028</PDBx:U12>
         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.1361</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.0674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2165">
         <PDBx:U11>0.1994</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.1017</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.0545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2166">
         <PDBx:U11>0.2526</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.1655</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.0854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2167">
         <PDBx:U11>0.2414</PDBx:U11>
         <PDBx:U12>-0.0014</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1649</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.0819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2168">
         <PDBx:U11>0.2308</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.1316</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.0578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2169">
         <PDBx:U11>0.3077</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.2009</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.1155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2170">
         <PDBx:U11>0.3545</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>-0.0066</PDBx:U13>
         <PDBx:U22>0.2576</PDBx:U22>
         <PDBx:U23>0.0015</PDBx:U23>
         <PDBx:U33>0.1698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2171">
         <PDBx:U11>0.2982</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.2135</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.1149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2172">
         <PDBx:U11>0.2190</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1288</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.0582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2173">
         <PDBx:U11>0.2050</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1247</PDBx:U22>
         <PDBx:U23>-0.0101</PDBx:U23>
         <PDBx:U33>0.0595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2174">
         <PDBx:U11>0.1964</PDBx:U11>
         <PDBx:U12>-0.0010</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1210</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.0540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2175">
         <PDBx:U11>0.1121</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.0506</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.0415</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2176">
         <PDBx:U11>0.2227</PDBx:U11>
         <PDBx:U12>-0.0089</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.1376</PDBx:U22>
         <PDBx:U23>-0.0126</PDBx:U23>
         <PDBx:U33>0.0621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2177">
         <PDBx:U11>0.2009</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1172</PDBx:U22>
         <PDBx:U23>-0.0154</PDBx:U23>
         <PDBx:U33>0.0549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2178">
         <PDBx:U11>0.2016</PDBx:U11>
         <PDBx:U12>0.0067</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1233</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.0616</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2179">
         <PDBx:U11>0.2016</PDBx:U11>
         <PDBx:U12>0.0083</PDBx:U12>
         <PDBx:U13>-0.0052</PDBx:U13>
         <PDBx:U22>0.1324</PDBx:U22>
         <PDBx:U23>-0.0210</PDBx:U23>
         <PDBx:U33>0.0663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2180">
         <PDBx:U11>0.1906</PDBx:U11>
         <PDBx:U12>0.0092</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.1316</PDBx:U22>
         <PDBx:U23>-0.0247</PDBx:U23>
         <PDBx:U33>0.0637</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2181">
         <PDBx:U11>0.2599</PDBx:U11>
         <PDBx:U12>0.0105</PDBx:U12>
         <PDBx:U13>-0.0120</PDBx:U13>
         <PDBx:U22>0.1705</PDBx:U22>
         <PDBx:U23>-0.0220</PDBx:U23>
         <PDBx:U33>0.1202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2182">
         <PDBx:U11>0.3525</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.2692</PDBx:U22>
         <PDBx:U23>-0.0280</PDBx:U23>
         <PDBx:U33>0.2251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2183">
         <PDBx:U11>0.4783</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>-0.0213</PDBx:U13>
         <PDBx:U22>0.3827</PDBx:U22>
         <PDBx:U23>-0.0294</PDBx:U23>
         <PDBx:U33>0.3508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2184">
         <PDBx:U11>0.4772</PDBx:U11>
         <PDBx:U12>0.0238</PDBx:U12>
         <PDBx:U13>-0.0236</PDBx:U13>
         <PDBx:U22>0.3880</PDBx:U22>
         <PDBx:U23>-0.0365</PDBx:U23>
         <PDBx:U33>0.3630</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2185">
         <PDBx:U11>0.3475</PDBx:U11>
         <PDBx:U12>0.0276</PDBx:U12>
         <PDBx:U13>-0.0266</PDBx:U13>
         <PDBx:U22>0.2644</PDBx:U22>
         <PDBx:U23>-0.0388</PDBx:U23>
         <PDBx:U33>0.2403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2186">
         <PDBx:U11>0.1865</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.1140</PDBx:U22>
         <PDBx:U23>-0.0156</PDBx:U23>
         <PDBx:U33>0.0522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2187">
         <PDBx:U11>0.1710</PDBx:U11>
         <PDBx:U12>0.0092</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.1066</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.0497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2188">
         <PDBx:U11>0.1951</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1410</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.0593</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2189">
         <PDBx:U11>0.1493</PDBx:U11>
         <PDBx:U12>0.0072</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1055</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.0492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2190">
         <PDBx:U11>0.1993</PDBx:U11>
         <PDBx:U12>0.0086</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.1276</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.0538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2191">
         <PDBx:U11>0.1941</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>-0.0151</PDBx:U13>
         <PDBx:U22>0.1124</PDBx:U22>
         <PDBx:U23>-0.0119</PDBx:U23>
         <PDBx:U33>0.0492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2192">
         <PDBx:U11>0.1936</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1307</PDBx:U22>
         <PDBx:U23>-0.0117</PDBx:U23>
         <PDBx:U33>0.0502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2193">
         <PDBx:U11>0.1391</PDBx:U11>
         <PDBx:U12>0.0105</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.0463</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.0395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2194">
         <PDBx:U11>0.1645</PDBx:U11>
         <PDBx:U12>0.0026</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.1107</PDBx:U22>
         <PDBx:U23>-0.0099</PDBx:U23>
         <PDBx:U33>0.0537</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2195">
         <PDBx:U11>0.1491</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.1043</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.0524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2196">
         <PDBx:U11>0.2243</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.1855</PDBx:U22>
         <PDBx:U23>-0.0195</PDBx:U23>
         <PDBx:U33>0.0906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2197">
         <PDBx:U11>0.2329</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.2018</PDBx:U22>
         <PDBx:U23>-0.0207</PDBx:U23>
         <PDBx:U33>0.1025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2198">
         <PDBx:U11>0.1726</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1251</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.0565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2199">
         <PDBx:U11>0.2132</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.1611</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.0610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2200">
         <PDBx:U11>0.2439</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.1891</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.0841</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2201">
         <PDBx:U11>0.2264</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.1600</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.0647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2202">
         <PDBx:U11>0.1636</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.1231</PDBx:U22>
         <PDBx:U23>-0.0158</PDBx:U23>
         <PDBx:U33>0.0580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2203">
         <PDBx:U11>0.1657</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.1314</PDBx:U22>
         <PDBx:U23>-0.0213</PDBx:U23>
         <PDBx:U33>0.0588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2204">
         <PDBx:U11>0.1832</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1532</PDBx:U22>
         <PDBx:U23>-0.0295</PDBx:U23>
         <PDBx:U33>0.0655</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2205">
         <PDBx:U11>0.1673</PDBx:U11>
         <PDBx:U12>0.0017</PDBx:U12>
         <PDBx:U13>0.0109</PDBx:U13>
         <PDBx:U22>0.1463</PDBx:U22>
         <PDBx:U23>-0.0310</PDBx:U23>
         <PDBx:U33>0.0578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2206">
         <PDBx:U11>0.1646</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.1248</PDBx:U22>
         <PDBx:U23>-0.0236</PDBx:U23>
         <PDBx:U33>0.0549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2207">
         <PDBx:U11>0.4102</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>0.0120</PDBx:U13>
         <PDBx:U22>0.3667</PDBx:U22>
         <PDBx:U23>-0.0262</PDBx:U23>
         <PDBx:U33>0.2797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2208">
         <PDBx:U11>0.6986</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.6489</PDBx:U22>
         <PDBx:U23>-0.0281</PDBx:U23>
         <PDBx:U33>0.5683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2209">
         <PDBx:U11>0.8496</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0141</PDBx:U13>
         <PDBx:U22>0.7969</PDBx:U22>
         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.7128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2210">
         <PDBx:U11>1.0042</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>0.0139</PDBx:U13>
         <PDBx:U22>0.9443</PDBx:U22>
         <PDBx:U23>-0.0273</PDBx:U23>
         <PDBx:U33>0.8649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2211">
         <PDBx:U11>0.8285</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.7630</PDBx:U22>
         <PDBx:U23>-0.0296</PDBx:U23>
         <PDBx:U33>0.6927</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2212">
         <PDBx:U11>0.8085</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0168</PDBx:U13>
         <PDBx:U22>0.7470</PDBx:U22>
         <PDBx:U23>-0.0262</PDBx:U23>
         <PDBx:U33>0.6631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2213">
         <PDBx:U11>0.1156</PDBx:U11>
         <PDBx:U12>0.0058</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.0856</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.0456</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2214">
         <PDBx:U11>0.1200</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.0964</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.0532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2215">
         <PDBx:U11>0.1947</PDBx:U11>
         <PDBx:U12>0.0078</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.1712</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.0843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2216">
         <PDBx:U11>0.2286</PDBx:U11>
         <PDBx:U12>0.0092</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.2102</PDBx:U22>
         <PDBx:U23>-0.0349</PDBx:U23>
         <PDBx:U33>0.1238</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2217">
         <PDBx:U11>0.1412</PDBx:U11>
         <PDBx:U12>0.0131</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.1090</PDBx:U22>
         <PDBx:U23>-0.0244</PDBx:U23>
         <PDBx:U33>0.0590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2218">
         <PDBx:U11>0.2758</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.2362</PDBx:U22>
         <PDBx:U23>-0.0384</PDBx:U23>
         <PDBx:U33>0.1738</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2219">
         <PDBx:U11>0.4685</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.4176</PDBx:U22>
         <PDBx:U23>-0.0384</PDBx:U23>
         <PDBx:U33>0.3660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2220">
         <PDBx:U11>0.5143</PDBx:U11>
         <PDBx:U12>0.0212</PDBx:U12>
         <PDBx:U13>-0.0147</PDBx:U13>
         <PDBx:U22>0.4578</PDBx:U22>
         <PDBx:U23>-0.0357</PDBx:U23>
         <PDBx:U33>0.4083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2221">
         <PDBx:U11>0.2825</PDBx:U11>
         <PDBx:U12>0.0203</PDBx:U12>
         <PDBx:U13>-0.0122</PDBx:U13>
         <PDBx:U22>0.2277</PDBx:U22>
         <PDBx:U23>-0.0414</PDBx:U23>
         <PDBx:U33>0.1828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2222">
         <PDBx:U11>0.0900</PDBx:U11>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U23>-0.0110</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0105</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0185</PDBx:U13>
         <PDBx:U22>0.1793</PDBx:U22>
         <PDBx:U23>-0.0313</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0211</PDBx:U13>
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         <PDBx:U23>-0.0317</PDBx:U23>
         <PDBx:U33>0.0695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.0800</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.0460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0071</PDBx:U13>
         <PDBx:U22>0.0836</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.0468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1104</PDBx:U22>
         <PDBx:U23>-0.0102</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.0798</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0073</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U22>0.1204</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U33>0.0418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2239">
         <PDBx:U11>0.1353</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.1084</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.0409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2240">
         <PDBx:U11>0.1357</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>0.0125</PDBx:U13>
         <PDBx:U22>0.1092</PDBx:U22>
         <PDBx:U23>-0.0111</PDBx:U23>
         <PDBx:U33>0.0430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2241">
         <PDBx:U11>0.1583</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>0.0135</PDBx:U13>
         <PDBx:U22>0.1297</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.0475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2242">
         <PDBx:U11>0.1260</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.1277</PDBx:U22>
         <PDBx:U23>-0.0226</PDBx:U23>
         <PDBx:U33>0.0603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2243">
         <PDBx:U11>0.1220</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.1316</PDBx:U22>
         <PDBx:U23>-0.0266</PDBx:U23>
         <PDBx:U33>0.0624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2244">
         <PDBx:U11>0.1614</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>0.0210</PDBx:U13>
         <PDBx:U22>0.1728</PDBx:U22>
         <PDBx:U23>-0.0385</PDBx:U23>
         <PDBx:U33>0.0613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2245">
         <PDBx:U11>0.1479</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.0183</PDBx:U13>
         <PDBx:U22>0.1591</PDBx:U22>
         <PDBx:U23>-0.0327</PDBx:U23>
         <PDBx:U33>0.0571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2246">
         <PDBx:U11>0.1488</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.1599</PDBx:U22>
         <PDBx:U23>-0.0382</PDBx:U23>
         <PDBx:U33>0.0752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2247">
         <PDBx:U11>0.2233</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0152</PDBx:U13>
         <PDBx:U22>0.2261</PDBx:U22>
         <PDBx:U23>-0.0484</PDBx:U23>
         <PDBx:U33>0.1306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2248">
         <PDBx:U11>0.2657</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>0.0165</PDBx:U13>
         <PDBx:U22>0.2673</PDBx:U22>
         <PDBx:U23>-0.0494</PDBx:U23>
         <PDBx:U33>0.1734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2249">
         <PDBx:U11>0.2482</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.2467</PDBx:U22>
         <PDBx:U23>-0.0489</PDBx:U23>
         <PDBx:U33>0.1588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2250">
         <PDBx:U11>0.3059</PDBx:U11>
         <PDBx:U12>0.0026</PDBx:U12>
         <PDBx:U13>0.0135</PDBx:U13>
         <PDBx:U22>0.3010</PDBx:U22>
         <PDBx:U23>-0.0504</PDBx:U23>
         <PDBx:U33>0.2163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2251">
         <PDBx:U11>0.2771</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.2688</PDBx:U22>
         <PDBx:U23>-0.0500</PDBx:U23>
         <PDBx:U33>0.1903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2252">
         <PDBx:U11>0.3867</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.3763</PDBx:U22>
         <PDBx:U23>-0.0506</PDBx:U23>
         <PDBx:U33>0.2995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2253">
         <PDBx:U11>0.4096</PDBx:U11>
         <PDBx:U12>0.0102</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.3912</PDBx:U22>
         <PDBx:U23>-0.0515</PDBx:U23>
         <PDBx:U33>0.3240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2254">
         <PDBx:U11>0.1083</PDBx:U11>
         <PDBx:U12>-0.0167</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.1260</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.0518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0666</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.4790</PDBx:U22>
         <PDBx:U23>-0.0722</PDBx:U23>
         <PDBx:U33>0.3500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0814</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0503</PDBx:U23>
         <PDBx:U33>0.0838</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2271">
         <PDBx:U11>0.1360</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>0.0183</PDBx:U13>
         <PDBx:U22>0.1750</PDBx:U22>
         <PDBx:U23>-0.0558</PDBx:U23>
         <PDBx:U33>0.0721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2272">
         <PDBx:U11>0.1381</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0170</PDBx:U13>
         <PDBx:U22>0.1798</PDBx:U22>
         <PDBx:U23>-0.0660</PDBx:U23>
         <PDBx:U33>0.0759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2273">
         <PDBx:U11>0.1871</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>0.0138</PDBx:U13>
         <PDBx:U22>0.2206</PDBx:U22>
         <PDBx:U23>-0.0697</PDBx:U23>
         <PDBx:U33>0.1201</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2274">
         <PDBx:U11>0.2207</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.2519</PDBx:U22>
         <PDBx:U23>-0.0710</PDBx:U23>
         <PDBx:U33>0.1587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2275">
         <PDBx:U11>0.1484</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.2002</PDBx:U22>
         <PDBx:U23>-0.0788</PDBx:U23>
         <PDBx:U33>0.0882</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2276">
         <PDBx:U11>0.1268</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1601</PDBx:U22>
         <PDBx:U23>-0.0587</PDBx:U23>
         <PDBx:U33>0.0729</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2277">
         <PDBx:U11>0.1149</PDBx:U11>
         <PDBx:U12>0.0037</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1428</PDBx:U22>
         <PDBx:U23>-0.0543</PDBx:U23>
         <PDBx:U33>0.0683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2278">
         <PDBx:U11>0.1822</PDBx:U11>
         <PDBx:U12>0.0083</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1934</PDBx:U22>
         <PDBx:U23>-0.0577</PDBx:U23>
         <PDBx:U33>0.1061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2279">
         <PDBx:U11>0.1764</PDBx:U11>
         <PDBx:U12>0.0126</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1802</PDBx:U22>
         <PDBx:U23>-0.0569</PDBx:U23>
         <PDBx:U33>0.1015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2280">
         <PDBx:U11>0.1241</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.1505</PDBx:U22>
         <PDBx:U23>-0.0579</PDBx:U23>
         <PDBx:U33>0.0703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2281">
         <PDBx:U11>0.1405</PDBx:U11>
         <PDBx:U12>0.0053</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.1533</PDBx:U22>
         <PDBx:U23>-0.0451</PDBx:U23>
         <PDBx:U33>0.0716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2282">
         <PDBx:U11>0.1315</PDBx:U11>
         <PDBx:U12>0.0072</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1361</PDBx:U22>
         <PDBx:U23>-0.0348</PDBx:U23>
         <PDBx:U33>0.0643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2283">
         <PDBx:U11>0.1619</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1586</PDBx:U22>
         <PDBx:U23>-0.0453</PDBx:U23>
         <PDBx:U33>0.0730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2284">
         <PDBx:U11>0.1554</PDBx:U11>
         <PDBx:U12>0.0139</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.1581</PDBx:U22>
         <PDBx:U23>-0.0501</PDBx:U23>
         <PDBx:U33>0.0731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2285">
         <PDBx:U11>0.1300</PDBx:U11>
         <PDBx:U12>0.0038</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1347</PDBx:U22>
         <PDBx:U23>-0.0298</PDBx:U23>
         <PDBx:U33>0.0594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2286">
         <PDBx:U11>0.1477</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1526</PDBx:U22>
         <PDBx:U23>-0.0317</PDBx:U23>
         <PDBx:U33>0.0646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2287">
         <PDBx:U11>0.0856</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.0935</PDBx:U22>
         <PDBx:U23>-0.0156</PDBx:U23>
         <PDBx:U33>0.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2288">
         <PDBx:U11>0.1302</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.1391</PDBx:U22>
         <PDBx:U23>-0.0240</PDBx:U23>
         <PDBx:U33>0.0577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2289">
         <PDBx:U11>0.2315</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0197</PDBx:U13>
         <PDBx:U22>0.2404</PDBx:U22>
         <PDBx:U23>-0.0339</PDBx:U23>
         <PDBx:U33>0.1120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2290">
         <PDBx:U11>0.0977</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1086</PDBx:U22>
         <PDBx:U23>-0.0172</PDBx:U23>
         <PDBx:U33>0.0435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2291">
         <PDBx:U11>0.2038</PDBx:U11>
         <PDBx:U12>-0.0136</PDBx:U12>
         <PDBx:U13>0.0221</PDBx:U13>
         <PDBx:U22>0.2145</PDBx:U22>
         <PDBx:U23>-0.0343</PDBx:U23>
         <PDBx:U33>0.0807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2292">
         <PDBx:U11>0.1321</PDBx:U11>
         <PDBx:U12>0.0148</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1212</PDBx:U22>
         <PDBx:U23>-0.0336</PDBx:U23>
         <PDBx:U33>0.0533</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2293">
         <PDBx:U11>0.1379</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.1210</PDBx:U22>
         <PDBx:U23>-0.0324</PDBx:U23>
         <PDBx:U33>0.0592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2294">
         <PDBx:U11>0.1823</PDBx:U11>
         <PDBx:U12>0.0184</PDBx:U12>
         <PDBx:U13>-0.0072</PDBx:U13>
         <PDBx:U22>0.1665</PDBx:U22>
         <PDBx:U23>-0.0376</PDBx:U23>
         <PDBx:U33>0.0863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2295">
         <PDBx:U11>0.1674</PDBx:U11>
         <PDBx:U12>0.0146</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1557</PDBx:U22>
         <PDBx:U23>-0.0354</PDBx:U23>
         <PDBx:U33>0.0674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2296">
         <PDBx:U11>0.1538</PDBx:U11>
         <PDBx:U12>0.0197</PDBx:U12>
         <PDBx:U13>-0.0103</PDBx:U13>
         <PDBx:U22>0.1228</PDBx:U22>
         <PDBx:U23>-0.0300</PDBx:U23>
         <PDBx:U33>0.0578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2297">
         <PDBx:U11>0.2167</PDBx:U11>
         <PDBx:U12>0.0201</PDBx:U12>
         <PDBx:U13>-0.0116</PDBx:U13>
         <PDBx:U22>0.1777</PDBx:U22>
         <PDBx:U23>-0.0333</PDBx:U23>
         <PDBx:U33>0.1122</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2298">
         <PDBx:U11>0.2033</PDBx:U11>
         <PDBx:U12>0.0185</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.1531</PDBx:U22>
         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.0877</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2299">
         <PDBx:U11>0.2871</PDBx:U11>
         <PDBx:U12>0.0250</PDBx:U12>
         <PDBx:U13>-0.0172</PDBx:U13>
         <PDBx:U22>0.2447</PDBx:U22>
         <PDBx:U23>-0.0382</PDBx:U23>
         <PDBx:U33>0.1898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2300">
         <PDBx:U11>0.1326</PDBx:U11>
         <PDBx:U12>0.0222</PDBx:U12>
         <PDBx:U13>-0.0112</PDBx:U13>
         <PDBx:U22>0.1185</PDBx:U22>
         <PDBx:U23>-0.0314</PDBx:U23>
         <PDBx:U33>0.0578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2301">
         <PDBx:U11>0.1309</PDBx:U11>
         <PDBx:U12>0.0217</PDBx:U12>
         <PDBx:U13>-0.0106</PDBx:U13>
         <PDBx:U22>0.1199</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.0599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2302">
         <PDBx:U11>0.1576</PDBx:U11>
         <PDBx:U12>0.0220</PDBx:U12>
         <PDBx:U13>-0.0134</PDBx:U13>
         <PDBx:U22>0.1332</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.0592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2303">
         <PDBx:U11>0.1478</PDBx:U11>
         <PDBx:U12>0.0239</PDBx:U12>
         <PDBx:U13>-0.0155</PDBx:U13>
         <PDBx:U22>0.1151</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.0576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2304">
         <PDBx:U11>0.2392</PDBx:U11>
         <PDBx:U12>0.0251</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.2293</PDBx:U22>
         <PDBx:U23>-0.0428</PDBx:U23>
         <PDBx:U33>0.1527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2305">
         <PDBx:U11>0.2249</PDBx:U11>
         <PDBx:U12>0.0300</PDBx:U12>
         <PDBx:U13>-0.0214</PDBx:U13>
         <PDBx:U22>0.2067</PDBx:U22>
         <PDBx:U23>-0.0434</PDBx:U23>
         <PDBx:U33>0.1400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2306">
         <PDBx:U11>0.1921</PDBx:U11>
         <PDBx:U12>0.0237</PDBx:U12>
         <PDBx:U13>-0.0117</PDBx:U13>
         <PDBx:U22>0.1943</PDBx:U22>
         <PDBx:U23>-0.0510</PDBx:U23>
         <PDBx:U33>0.1154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2307">
         <PDBx:U11>0.1125</PDBx:U11>
         <PDBx:U12>0.0209</PDBx:U12>
         <PDBx:U13>-0.0099</PDBx:U13>
         <PDBx:U22>0.0915</PDBx:U22>
         <PDBx:U23>-0.0149</PDBx:U23>
         <PDBx:U33>0.0457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2308">
         <PDBx:U11>0.1384</PDBx:U11>
         <PDBx:U12>0.0204</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.1070</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.0522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2309">
         <PDBx:U11>0.1597</PDBx:U11>
         <PDBx:U12>0.0243</PDBx:U12>
         <PDBx:U13>-0.0185</PDBx:U13>
         <PDBx:U22>0.1196</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.0590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2310">
         <PDBx:U11>0.1575</PDBx:U11>
         <PDBx:U12>0.0241</PDBx:U12>
         <PDBx:U13>-0.0198</PDBx:U13>
         <PDBx:U22>0.1068</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2311">
         <PDBx:U11>0.1521</PDBx:U11>
         <PDBx:U12>0.0179</PDBx:U12>
         <PDBx:U13>-0.0098</PDBx:U13>
         <PDBx:U22>0.1238</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.0568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2312">
         <PDBx:U11>0.1422</PDBx:U11>
         <PDBx:U12>0.0282</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.1070</PDBx:U22>
         <PDBx:U23>-0.0191</PDBx:U23>
         <PDBx:U33>0.0552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2313">
         <PDBx:U11>0.1723</PDBx:U11>
         <PDBx:U12>0.0318</PDBx:U12>
         <PDBx:U13>-0.0310</PDBx:U13>
         <PDBx:U22>0.1285</PDBx:U22>
         <PDBx:U23>-0.0256</PDBx:U23>
         <PDBx:U33>0.0623</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2314">
         <PDBx:U11>0.2581</PDBx:U11>
         <PDBx:U12>0.0338</PDBx:U12>
         <PDBx:U13>-0.0347</PDBx:U13>
         <PDBx:U22>0.2054</PDBx:U22>
         <PDBx:U23>-0.0262</PDBx:U23>
         <PDBx:U33>0.1474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2315">
         <PDBx:U11>0.2869</PDBx:U11>
         <PDBx:U12>0.0351</PDBx:U12>
         <PDBx:U13>-0.0397</PDBx:U13>
         <PDBx:U22>0.2222</PDBx:U22>
         <PDBx:U23>-0.0225</PDBx:U23>
         <PDBx:U33>0.1691</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2316">
         <PDBx:U11>0.1815</PDBx:U11>
         <PDBx:U12>0.0352</PDBx:U12>
         <PDBx:U13>-0.0333</PDBx:U13>
         <PDBx:U22>0.1464</PDBx:U22>
         <PDBx:U23>-0.0321</PDBx:U23>
         <PDBx:U33>0.0820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2317">
         <PDBx:U11>0.2740</PDBx:U11>
         <PDBx:U12>0.0406</PDBx:U12>
         <PDBx:U13>-0.0414</PDBx:U13>
         <PDBx:U22>0.2330</PDBx:U22>
         <PDBx:U23>-0.0338</PDBx:U23>
         <PDBx:U33>0.1765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2318">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>0.0400</PDBx:U12>
         <PDBx:U13>-0.0433</PDBx:U13>
         <PDBx:U22>0.2253</PDBx:U22>
         <PDBx:U23>-0.0284</PDBx:U23>
         <PDBx:U33>0.1657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2319">
         <PDBx:U11>0.3256</PDBx:U11>
         <PDBx:U12>0.0440</PDBx:U12>
         <PDBx:U13>-0.0429</PDBx:U13>
         <PDBx:U22>0.2958</PDBx:U22>
         <PDBx:U23>-0.0427</PDBx:U23>
         <PDBx:U33>0.2416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>288</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2320">
         <PDBx:U11>0.2002</PDBx:U11>
         <PDBx:U12>0.0335</PDBx:U12>
         <PDBx:U13>-0.0320</PDBx:U13>
         <PDBx:U22>0.1528</PDBx:U22>
         <PDBx:U23>-0.0304</PDBx:U23>
         <PDBx:U33>0.0959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2321">
         <PDBx:U11>0.2139</PDBx:U11>
         <PDBx:U12>0.0351</PDBx:U12>
         <PDBx:U13>-0.0350</PDBx:U13>
         <PDBx:U22>0.1583</PDBx:U22>
         <PDBx:U23>-0.0311</PDBx:U23>
         <PDBx:U33>0.1091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2322">
         <PDBx:U11>0.2433</PDBx:U11>
         <PDBx:U12>0.0315</PDBx:U12>
         <PDBx:U13>-0.0336</PDBx:U13>
         <PDBx:U22>0.1770</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.1260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2323">
         <PDBx:U11>0.2085</PDBx:U11>
         <PDBx:U12>0.0329</PDBx:U12>
         <PDBx:U13>-0.0384</PDBx:U13>
         <PDBx:U22>0.1300</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.0859</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2324">
         <PDBx:U11>0.2135</PDBx:U11>
         <PDBx:U12>0.0352</PDBx:U12>
         <PDBx:U13>-0.0319</PDBx:U13>
         <PDBx:U22>0.1671</PDBx:U22>
         <PDBx:U23>-0.0377</PDBx:U23>
         <PDBx:U33>0.1188</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2325">
         <PDBx:U11>0.2219</PDBx:U11>
         <PDBx:U12>0.0363</PDBx:U12>
         <PDBx:U13>-0.0339</PDBx:U13>
         <PDBx:U22>0.1679</PDBx:U22>
         <PDBx:U23>-0.0387</PDBx:U23>
         <PDBx:U33>0.1270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2326">
         <PDBx:U11>0.3839</PDBx:U11>
         <PDBx:U12>0.0414</PDBx:U12>
         <PDBx:U13>-0.0425</PDBx:U13>
         <PDBx:U22>0.3173</PDBx:U22>
         <PDBx:U23>-0.0392</PDBx:U23>
         <PDBx:U33>0.2881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2327">
         <PDBx:U11>0.5048</PDBx:U11>
         <PDBx:U12>0.0469</PDBx:U12>
         <PDBx:U13>-0.0474</PDBx:U13>
         <PDBx:U22>0.4438</PDBx:U22>
         <PDBx:U23>-0.0466</PDBx:U23>
         <PDBx:U33>0.4209</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2328">
         <PDBx:U11>0.7490</PDBx:U11>
         <PDBx:U12>0.0524</PDBx:U12>
         <PDBx:U13>-0.0562</PDBx:U13>
         <PDBx:U22>0.6785</PDBx:U22>
         <PDBx:U23>-0.0480</PDBx:U23>
         <PDBx:U33>0.6658</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2329">
         <PDBx:U11>0.5644</PDBx:U11>
         <PDBx:U12>0.0526</PDBx:U12>
         <PDBx:U13>-0.0611</PDBx:U13>
         <PDBx:U22>0.4770</PDBx:U22>
         <PDBx:U23>-0.0419</PDBx:U23>
         <PDBx:U33>0.4693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2330">
         <PDBx:U11>0.6494</PDBx:U11>
         <PDBx:U12>0.0575</PDBx:U12>
         <PDBx:U13>-0.0604</PDBx:U13>
         <PDBx:U22>0.5859</PDBx:U22>
         <PDBx:U23>-0.0558</PDBx:U23>
         <PDBx:U33>0.5786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>289</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2331">
         <PDBx:U11>0.2228</PDBx:U11>
         <PDBx:U12>0.0267</PDBx:U12>
         <PDBx:U13>-0.0274</PDBx:U13>
         <PDBx:U22>0.1610</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.1007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2332">
         <PDBx:U11>0.2094</PDBx:U11>
         <PDBx:U12>0.0227</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>0.1399</PDBx:U22>
         <PDBx:U23>-0.0150</PDBx:U23>
         <PDBx:U33>0.0764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2333">
         <PDBx:U11>0.2732</PDBx:U11>
         <PDBx:U12>0.0228</PDBx:U12>
         <PDBx:U13>-0.0298</PDBx:U13>
         <PDBx:U22>0.1929</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.1310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2334">
         <PDBx:U11>0.2527</PDBx:U11>
         <PDBx:U12>0.0211</PDBx:U12>
         <PDBx:U13>-0.0317</PDBx:U13>
         <PDBx:U22>0.1609</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.1015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2335">
         <PDBx:U11>0.2368</PDBx:U11>
         <PDBx:U12>0.0184</PDBx:U12>
         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.1761</PDBx:U22>
         <PDBx:U23>-0.0134</PDBx:U23>
         <PDBx:U33>0.1026</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2336">
         <PDBx:U11>0.2297</PDBx:U11>
         <PDBx:U12>0.0177</PDBx:U12>
         <PDBx:U13>-0.0144</PDBx:U13>
         <PDBx:U22>0.1772</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.1023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2337">
         <PDBx:U11>0.2311</PDBx:U11>
         <PDBx:U12>0.0144</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.1637</PDBx:U22>
         <PDBx:U23>-0.0084</PDBx:U23>
         <PDBx:U33>0.0865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2338">
         <PDBx:U11>0.2247</PDBx:U11>
         <PDBx:U12>0.0147</PDBx:U12>
         <PDBx:U13>-0.0089</PDBx:U13>
         <PDBx:U22>0.1825</PDBx:U22>
         <PDBx:U23>-0.0175</PDBx:U23>
         <PDBx:U33>0.0986</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>290</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2339">
         <PDBx:U11>0.2258</PDBx:U11>
         <PDBx:U12>0.0243</PDBx:U12>
         <PDBx:U13>-0.0313</PDBx:U13>
         <PDBx:U22>0.1492</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.0855</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2340">
         <PDBx:U11>0.2283</PDBx:U11>
         <PDBx:U12>0.0245</PDBx:U12>
         <PDBx:U13>-0.0357</PDBx:U13>
         <PDBx:U22>0.1426</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.0799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2341">
         <PDBx:U11>0.2658</PDBx:U11>
         <PDBx:U12>0.0280</PDBx:U12>
         <PDBx:U13>-0.0433</PDBx:U13>
         <PDBx:U22>0.1676</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.1152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2342">
         <PDBx:U11>0.2870</PDBx:U11>
         <PDBx:U12>0.0259</PDBx:U12>
         <PDBx:U13>-0.0459</PDBx:U13>
         <PDBx:U22>0.1759</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2343">
         <PDBx:U11>0.2167</PDBx:U11>
         <PDBx:U12>0.0264</PDBx:U12>
         <PDBx:U13>-0.0363</PDBx:U13>
         <PDBx:U22>0.1386</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.0731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2344">
         <PDBx:U11>0.2863</PDBx:U11>
         <PDBx:U12>0.0269</PDBx:U12>
         <PDBx:U13>-0.0415</PDBx:U13>
         <PDBx:U22>0.1988</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1348</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2345">
         <PDBx:U11>0.3772</PDBx:U11>
         <PDBx:U12>0.0284</PDBx:U12>
         <PDBx:U13>-0.0418</PDBx:U13>
         <PDBx:U22>0.2974</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.2303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2346">
         <PDBx:U11>0.3678</PDBx:U11>
         <PDBx:U12>0.0290</PDBx:U12>
         <PDBx:U13>-0.0476</PDBx:U13>
         <PDBx:U22>0.2777</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.2126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2347">
         <PDBx:U11>0.2755</PDBx:U11>
         <PDBx:U12>0.0295</PDBx:U12>
         <PDBx:U13>-0.0470</PDBx:U13>
         <PDBx:U22>0.1928</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2348">
         <PDBx:U11>0.2066</PDBx:U11>
         <PDBx:U12>0.0330</PDBx:U12>
         <PDBx:U13>-0.0466</PDBx:U13>
         <PDBx:U22>0.1119</PDBx:U22>
         <PDBx:U23>-0.0127</PDBx:U23>
         <PDBx:U33>0.0665</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2349">
         <PDBx:U11>0.2286</PDBx:U11>
         <PDBx:U12>0.0373</PDBx:U12>
         <PDBx:U13>-0.0548</PDBx:U13>
         <PDBx:U22>0.1220</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.0876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2350">
         <PDBx:U11>0.2704</PDBx:U11>
         <PDBx:U12>0.0345</PDBx:U12>
         <PDBx:U13>-0.0548</PDBx:U13>
         <PDBx:U22>0.1519</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.1203</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2351">
         <PDBx:U11>0.3034</PDBx:U11>
         <PDBx:U12>0.0336</PDBx:U12>
         <PDBx:U13>-0.0598</PDBx:U13>
         <PDBx:U22>0.1698</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2352">
         <PDBx:U11>0.2798</PDBx:U11>
         <PDBx:U12>0.0433</PDBx:U12>
         <PDBx:U13>-0.0580</PDBx:U13>
         <PDBx:U22>0.1810</PDBx:U22>
         <PDBx:U23>-0.0219</PDBx:U23>
         <PDBx:U33>0.1534</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2353">
         <PDBx:U11>0.4807</PDBx:U11>
         <PDBx:U12>0.0463</PDBx:U12>
         <PDBx:U13>-0.0597</PDBx:U13>
         <PDBx:U22>0.3911</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.3620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2354">
         <PDBx:U11>0.6013</PDBx:U11>
         <PDBx:U12>0.0510</PDBx:U12>
         <PDBx:U13>-0.0610</PDBx:U13>
         <PDBx:U22>0.5227</PDBx:U22>
         <PDBx:U23>-0.0343</PDBx:U23>
         <PDBx:U33>0.4983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2355">
         <PDBx:U11>0.6317</PDBx:U11>
         <PDBx:U12>0.0532</PDBx:U12>
         <PDBx:U13>-0.0619</PDBx:U13>
         <PDBx:U22>0.5633</PDBx:U22>
         <PDBx:U23>-0.0380</PDBx:U23>
         <PDBx:U33>0.5362</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2356">
         <PDBx:U11>0.7022</PDBx:U11>
         <PDBx:U12>0.0576</PDBx:U12>
         <PDBx:U13>-0.0636</PDBx:U13>
         <PDBx:U22>0.6447</PDBx:U22>
         <PDBx:U23>-0.0480</PDBx:U23>
         <PDBx:U33>0.6224</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2357">
         <PDBx:U11>0.2349</PDBx:U11>
         <PDBx:U12>0.0321</PDBx:U12>
         <PDBx:U13>-0.0487</PDBx:U13>
         <PDBx:U22>0.1230</PDBx:U22>
         <PDBx:U23>-0.0127</PDBx:U23>
         <PDBx:U33>0.0885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>293</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2358">
         <PDBx:U11>0.2472</PDBx:U11>
         <PDBx:U12>0.0288</PDBx:U12>
         <PDBx:U13>-0.0474</PDBx:U13>
         <PDBx:U22>0.1261</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.0931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>293</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2359">
         <PDBx:U11>0.3197</PDBx:U11>
         <PDBx:U12>0.0231</PDBx:U12>
         <PDBx:U13>-0.0462</PDBx:U13>
         <PDBx:U22>0.1881</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>293</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2360">
         <PDBx:U11>0.3240</PDBx:U11>
         <PDBx:U12>0.0219</PDBx:U12>
         <PDBx:U13>-0.0505</PDBx:U13>
         <PDBx:U22>0.1770</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>293</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2361">
         <PDBx:U11>0.2685</PDBx:U11>
         <PDBx:U12>0.0268</PDBx:U12>
         <PDBx:U13>-0.0403</PDBx:U13>
         <PDBx:U22>0.1589</PDBx:U22>
         <PDBx:U23>-0.0134</PDBx:U23>
         <PDBx:U33>0.1215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>293</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2362">
         <PDBx:U11>0.3329</PDBx:U11>
         <PDBx:U12>0.0314</PDBx:U12>
         <PDBx:U13>-0.0417</PDBx:U13>
         <PDBx:U22>0.2314</PDBx:U22>
         <PDBx:U23>-0.0200</PDBx:U23>
         <PDBx:U33>0.1992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>293</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2363">
         <PDBx:U11>0.2342</PDBx:U11>
         <PDBx:U12>0.0232</PDBx:U12>
         <PDBx:U13>-0.0385</PDBx:U13>
         <PDBx:U22>0.1161</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.0798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>293</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2364">
         <PDBx:U11>0.2548</PDBx:U11>
         <PDBx:U12>0.0193</PDBx:U12>
         <PDBx:U13>-0.0407</PDBx:U13>
         <PDBx:U22>0.1314</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.0834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2365">
         <PDBx:U11>0.2663</PDBx:U11>
         <PDBx:U12>0.0134</PDBx:U12>
         <PDBx:U13>-0.0387</PDBx:U13>
         <PDBx:U22>0.1354</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.0815</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2366">
         <PDBx:U11>0.3072</PDBx:U11>
         <PDBx:U12>0.0135</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.1637</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.1127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2367">
         <PDBx:U11>0.2958</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0457</PDBx:U13>
         <PDBx:U22>0.1399</PDBx:U22>
         <PDBx:U23>0.0107</PDBx:U23>
         <PDBx:U33>0.0881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2368">
         <PDBx:U11>0.2444</PDBx:U11>
         <PDBx:U12>0.0097</PDBx:U12>
         <PDBx:U13>-0.0315</PDBx:U13>
         <PDBx:U22>0.1255</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.0608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2369">
         <PDBx:U11>0.2702</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>-0.0253</PDBx:U13>
         <PDBx:U22>0.1624</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.0936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2370">
         <PDBx:U11>0.2549</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.1597</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.0824</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2371">
         <PDBx:U11>0.2782</PDBx:U11>
         <PDBx:U12>0.0037</PDBx:U12>
         <PDBx:U13>-0.0223</PDBx:U13>
         <PDBx:U22>0.1645</PDBx:U22>
         <PDBx:U23>0.0034</PDBx:U23>
         <PDBx:U33>0.0938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2372">
         <PDBx:U11>0.2690</PDBx:U11>
         <PDBx:U12>0.0186</PDBx:U12>
         <PDBx:U13>-0.0497</PDBx:U13>
         <PDBx:U22>0.1281</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.0804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2373">
         <PDBx:U11>0.2648</PDBx:U11>
         <PDBx:U12>0.0193</PDBx:U12>
         <PDBx:U13>-0.0560</PDBx:U13>
         <PDBx:U22>0.1112</PDBx:U22>
         <PDBx:U23>0.0079</PDBx:U23>
         <PDBx:U33>0.0700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2374">
         <PDBx:U11>0.3795</PDBx:U11>
         <PDBx:U12>0.0204</PDBx:U12>
         <PDBx:U13>-0.0639</PDBx:U13>
         <PDBx:U22>0.2080</PDBx:U22>
         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.1737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2375">
         <PDBx:U11>0.3816</PDBx:U11>
         <PDBx:U12>0.0169</PDBx:U12>
         <PDBx:U13>-0.0675</PDBx:U13>
         <PDBx:U22>0.1951</PDBx:U22>
         <PDBx:U23>0.0141</PDBx:U23>
         <PDBx:U33>0.1611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2376">
         <PDBx:U11>0.3017</PDBx:U11>
         <PDBx:U12>0.0257</PDBx:U12>
         <PDBx:U13>-0.0612</PDBx:U13>
         <PDBx:U22>0.1552</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.1143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2377">
         <PDBx:U11>0.4025</PDBx:U11>
         <PDBx:U12>0.0243</PDBx:U12>
         <PDBx:U13>-0.0561</PDBx:U13>
         <PDBx:U22>0.2688</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.2192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2378">
         <PDBx:U11>0.3229</PDBx:U11>
         <PDBx:U12>0.0250</PDBx:U12>
         <PDBx:U13>-0.0659</PDBx:U13>
         <PDBx:U22>0.1525</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>0.1260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2379">
         <PDBx:U11>0.3600</PDBx:U11>
         <PDBx:U12>0.0270</PDBx:U12>
         <PDBx:U13>-0.0727</PDBx:U13>
         <PDBx:U22>0.1737</PDBx:U22>
         <PDBx:U23>0.0050</PDBx:U23>
         <PDBx:U33>0.1580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2380">
         <PDBx:U11>0.4887</PDBx:U11>
         <PDBx:U12>0.0198</PDBx:U12>
         <PDBx:U13>-0.0689</PDBx:U13>
         <PDBx:U22>0.2924</PDBx:U22>
         <PDBx:U23>0.0087</PDBx:U23>
         <PDBx:U33>0.2736</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2381">
         <PDBx:U11>0.5458</PDBx:U11>
         <PDBx:U12>0.0189</PDBx:U12>
         <PDBx:U13>-0.0747</PDBx:U13>
         <PDBx:U22>0.3313</PDBx:U22>
         <PDBx:U23>0.0109</PDBx:U23>
         <PDBx:U33>0.3193</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2382">
         <PDBx:U11>0.3636</PDBx:U11>
         <PDBx:U12>0.0332</PDBx:U12>
         <PDBx:U13>-0.0738</PDBx:U13>
         <PDBx:U22>0.1855</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2383">
         <PDBx:U11>0.7130</PDBx:U11>
         <PDBx:U12>0.0409</PDBx:U12>
         <PDBx:U13>-0.0795</PDBx:U13>
         <PDBx:U22>0.5420</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.5394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2384">
         <PDBx:U11>1.0327</PDBx:U11>
         <PDBx:U12>0.0465</PDBx:U12>
         <PDBx:U13>-0.0914</PDBx:U13>
         <PDBx:U22>0.8458</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.8557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2385">
         <PDBx:U11>1.0084</PDBx:U11>
         <PDBx:U12>0.0455</PDBx:U12>
         <PDBx:U13>-0.0962</PDBx:U13>
         <PDBx:U22>0.8036</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.8203</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2386">
         <PDBx:U11>0.9084</PDBx:U11>
         <PDBx:U12>0.0527</PDBx:U12>
         <PDBx:U13>-0.0965</PDBx:U13>
         <PDBx:U22>0.7278</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.7413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2387">
         <PDBx:U11>0.4310</PDBx:U11>
         <PDBx:U12>0.0147</PDBx:U12>
         <PDBx:U13>-0.0594</PDBx:U13>
         <PDBx:U22>0.2464</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.2174</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2388">
         <PDBx:U11>0.4312</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.0544</PDBx:U13>
         <PDBx:U22>0.2406</PDBx:U22>
         <PDBx:U23>0.0115</PDBx:U23>
         <PDBx:U33>0.2068</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2389">
         <PDBx:U11>0.4858</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>-0.0541</PDBx:U13>
         <PDBx:U22>0.2861</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.2458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2390">
         <PDBx:U11>0.5037</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>-0.0550</PDBx:U13>
         <PDBx:U22>0.2893</PDBx:U22>
         <PDBx:U23>0.0193</PDBx:U23>
         <PDBx:U33>0.2494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2391">
         <PDBx:U11>0.4106</PDBx:U11>
         <PDBx:U12>0.0053</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.2376</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.1956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2392">
         <PDBx:U11>0.4726</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>-0.0387</PDBx:U13>
         <PDBx:U22>0.2978</PDBx:U22>
         <PDBx:U23>0.0104</PDBx:U23>
         <PDBx:U33>0.2493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2393">
         <PDBx:U11>0.4835</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>-0.0403</PDBx:U13>
         <PDBx:U22>0.2995</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.2583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2394">
         <PDBx:U11>0.4523</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>-0.0304</PDBx:U13>
         <PDBx:U22>0.2960</PDBx:U22>
         <PDBx:U23>0.0083</PDBx:U23>
         <PDBx:U33>0.2383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2395">
         <PDBx:U11>0.4407</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>-0.0527</PDBx:U13>
         <PDBx:U22>0.2496</PDBx:U22>
         <PDBx:U23>0.0175</PDBx:U23>
         <PDBx:U33>0.2031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2396">
         <PDBx:U11>0.4521</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>-0.0517</PDBx:U13>
         <PDBx:U22>0.2549</PDBx:U22>
         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.2012</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2397">
         <PDBx:U11>0.5479</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>-0.0605</PDBx:U13>
         <PDBx:U22>0.3298</PDBx:U22>
         <PDBx:U23>0.0251</PDBx:U23>
         <PDBx:U33>0.2825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2398">
         <PDBx:U11>0.5619</PDBx:U11>
         <PDBx:U12>-0.0135</PDBx:U12>
         <PDBx:U13>-0.0599</PDBx:U13>
         <PDBx:U22>0.3311</PDBx:U22>
         <PDBx:U23>0.0283</PDBx:U23>
         <PDBx:U33>0.2805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2399">
         <PDBx:U11>0.4751</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>-0.0488</PDBx:U13>
         <PDBx:U22>0.2921</PDBx:U22>
         <PDBx:U23>0.0213</PDBx:U23>
         <PDBx:U33>0.2315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2400">
         <PDBx:U11>0.6014</PDBx:U11>
         <PDBx:U12>0.0025</PDBx:U12>
         <PDBx:U13>-0.0555</PDBx:U13>
         <PDBx:U22>0.4182</PDBx:U22>
         <PDBx:U23>0.0205</PDBx:U23>
         <PDBx:U33>0.3638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2401">
         <PDBx:U11>0.5113</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>-0.0688</PDBx:U13>
         <PDBx:U22>0.2895</PDBx:U22>
         <PDBx:U23>0.0242</PDBx:U23>
         <PDBx:U33>0.2511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2402">
         <PDBx:U11>0.5446</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>-0.0789</PDBx:U13>
         <PDBx:U22>0.3023</PDBx:U22>
         <PDBx:U23>0.0273</PDBx:U23>
         <PDBx:U33>0.2714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2403">
         <PDBx:U11>0.6343</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>-0.0818</PDBx:U13>
         <PDBx:U22>0.3720</PDBx:U22>
         <PDBx:U23>0.0296</PDBx:U23>
         <PDBx:U33>0.3460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2404">
         <PDBx:U11>0.6629</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>-0.0859</PDBx:U13>
         <PDBx:U22>0.3831</PDBx:U22>
         <PDBx:U23>0.0340</PDBx:U23>
         <PDBx:U33>0.3566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2405">
         <PDBx:U11>0.5629</PDBx:U11>
         <PDBx:U12>0.0126</PDBx:U12>
         <PDBx:U13>-0.0876</PDBx:U13>
         <PDBx:U22>0.3218</PDBx:U22>
         <PDBx:U23>0.0242</PDBx:U23>
         <PDBx:U33>0.3013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2406">
         <PDBx:U11>0.8004</PDBx:U11>
         <PDBx:U12>0.0193</PDBx:U12>
         <PDBx:U13>-0.0887</PDBx:U13>
         <PDBx:U22>0.5651</PDBx:U22>
         <PDBx:U23>0.0188</PDBx:U23>
         <PDBx:U33>0.5534</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2407">
         <PDBx:U11>1.1599</PDBx:U11>
         <PDBx:U12>0.0290</PDBx:U12>
         <PDBx:U13>-0.0951</PDBx:U13>
         <PDBx:U22>0.9318</PDBx:U22>
         <PDBx:U23>0.0140</PDBx:U23>
         <PDBx:U33>0.9279</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2408">
         <PDBx:U11>1.1269</PDBx:U11>
         <PDBx:U12>0.0311</PDBx:U12>
         <PDBx:U13>-0.0958</PDBx:U13>
         <PDBx:U22>0.9069</PDBx:U22>
         <PDBx:U23>0.0136</PDBx:U23>
         <PDBx:U33>0.8995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2409">
         <PDBx:U11>1.0740</PDBx:U11>
         <PDBx:U12>0.0349</PDBx:U12>
         <PDBx:U13>-0.0995</PDBx:U13>
         <PDBx:U22>0.8441</PDBx:U22>
         <PDBx:U23>0.0095</PDBx:U23>
         <PDBx:U33>0.8507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2410">
         <PDBx:U11>0.5923</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>-0.0791</PDBx:U13>
         <PDBx:U22>0.3327</PDBx:U22>
         <PDBx:U23>0.0267</PDBx:U23>
         <PDBx:U33>0.3105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2411">
         <PDBx:U11>0.6151</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>-0.0809</PDBx:U13>
         <PDBx:U22>0.3385</PDBx:U22>
         <PDBx:U23>0.0281</PDBx:U23>
         <PDBx:U33>0.3210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2412">
         <PDBx:U11>0.6833</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>-0.0736</PDBx:U13>
         <PDBx:U22>0.4022</PDBx:U22>
         <PDBx:U23>0.0313</PDBx:U23>
         <PDBx:U33>0.3737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2413">
         <PDBx:U11>0.7266</PDBx:U11>
         <PDBx:U12>-0.0222</PDBx:U12>
         <PDBx:U13>-0.0773</PDBx:U13>
         <PDBx:U22>0.4251</PDBx:U22>
         <PDBx:U23>0.0348</PDBx:U23>
         <PDBx:U33>0.3983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2414">
         <PDBx:U11>0.6221</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>-0.0780</PDBx:U13>
         <PDBx:U22>0.3542</PDBx:U22>
         <PDBx:U23>0.0234</PDBx:U23>
         <PDBx:U33>0.3418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2415">
         <PDBx:U11>0.8641</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>-0.0852</PDBx:U13>
         <PDBx:U22>0.5993</PDBx:U22>
         <PDBx:U23>0.0191</PDBx:U23>
         <PDBx:U33>0.5987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2416">
         <PDBx:U11>1.1315</PDBx:U11>
         <PDBx:U12>0.0124</PDBx:U12>
         <PDBx:U13>-0.0821</PDBx:U13>
         <PDBx:U22>0.8733</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.8771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2417">
         <PDBx:U11>1.0887</PDBx:U11>
         <PDBx:U12>0.0114</PDBx:U12>
         <PDBx:U13>-0.0853</PDBx:U13>
         <PDBx:U22>0.8158</PDBx:U22>
         <PDBx:U23>0.0148</PDBx:U23>
         <PDBx:U33>0.8269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>301</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>301</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>301</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>J.Med.Chem.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMCMAR</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0151</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0022-2623</PDBx:journal_id_ISSN>
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         <PDBx:page_first>457</PDBx:page_first>
         <PDBx:page_last>465</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1021/jm501597j</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>25437144</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>Selection of fragments for kinase inhibitor design: decoration is key.</PDBx:title>
         <PDBx:year>2015</PDBx:year>
      </PDBx:citation>
   </PDBx:citationCategory>
   <PDBx:citation_authorCategory>
      <PDBx:citation_author citation_id="primary" name="Czodrowski, P." ordinal="1"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Holzemann, G." ordinal="2"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Barnickel, G." ordinal="3"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Greiner, H." ordinal="4"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Musil, D." ordinal="5"></PDBx:citation_author>
   </PDBx:citation_authorCategory>
   <PDBx:database_2Category>
      <PDBx:database_2 database_code="4X0M" database_id="PDB"></PDBx:database_2>
      <PDBx:database_2 database_code="D_1000204873" database_id="WWPDB"></PDBx:database_2>
   </PDBx:database_2Category>
   <PDBx:diffrnCategory>
      <PDBx:diffrn id="1">
         <PDBx:ambient_temp>100</PDBx:ambient_temp>
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
   </PDBx:diffrnCategory>
   <PDBx:diffrn_detectorCategory>
      <PDBx:diffrn_detector diffrn_id="1">
         <PDBx:detector>PIXEL</PDBx:detector>
         <PDBx:pdbx_collection_date>2007-12-13</PDBx:pdbx_collection_date>
         <PDBx:type>DECTRIS PILATUS 6M</PDBx:type>
      </PDBx:diffrn_detector>
   </PDBx:diffrn_detectorCategory>
   <PDBx:diffrn_radiationCategory>
      <PDBx:diffrn_radiation diffrn_id="1">
         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>1.00000</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_synchrotron_beamline>X06SA</PDBx:pdbx_synchrotron_beamline>
         <PDBx:pdbx_synchrotron_site>SLS</PDBx:pdbx_synchrotron_site>
         <PDBx:pdbx_wavelength_list>1.00000</PDBx:pdbx_wavelength_list>
         <PDBx:source>SYNCHROTRON</PDBx:source>
         <PDBx:type>SLS BEAMLINE X06SA</PDBx:type>
      </PDBx:diffrn_source>
   </PDBx:diffrn_sourceCategory>
   <PDBx:entityCategory>
      <PDBx:entity id="1">
         <PDBx:formula_weight>34882.148</PDBx:formula_weight>
         <PDBx:pdbx_description>TGF-beta receptor type-1</PDBx:pdbx_description>
         <PDBx:pdbx_ec>2.7.11.30</PDBx:pdbx_ec>
         <PDBx:pdbx_fragment>UNP residues 200-503</PDBx:pdbx_fragment>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>man</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="2">
         <PDBx:formula_weight>162.149</PDBx:formula_weight>
         <PDBx:pdbx_description>4-aminopyrido[2,3-d]pyrimidin-5(8H)-one</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="3">
         <PDBx:formula_weight>96.063</PDBx:formula_weight>
         <PDBx:pdbx_description>SULFATE ION</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="4">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>173</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_name_comCategory>
      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>TGFR-1,Activin A receptor type II-like protein kinase of 53kD,Activin receptor-like kinase 5,ALK5,Serine/threonine-protein kinase receptor R4,SKR4,TGF-beta type I receptor,Transforming growth factor-beta receptor type I,TbetaR-I</PDBx:name>
      </PDBx:entity_name_com>
   </PDBx:entity_name_comCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>GTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWL
VSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRH
DSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSV
EEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>GTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWL
VSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRH
DSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSV
EEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="14">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="15">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="16">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="17">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="18">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="19">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="20">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="21">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="22">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="23">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="24">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="25">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="26">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="27">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="28">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="29">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="30">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="31">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="159">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="160">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="161">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="162">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="163">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="164">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="165">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="166">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="167">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="168">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="169">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="170">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="171">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="172">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="173">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="174">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="175">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="176">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="177">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="178">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="179">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="180">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="181">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="182">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="183">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="184">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="185">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="186">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="187">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="188">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="189">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="190">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="191">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="192">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="193">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="194">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="195">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="196">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="197">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="198">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="199">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="200">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="201">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="202">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="203">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="204">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="205">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="206">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="207">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="208">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="209">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="210">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="211">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="212">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="213">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="214">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="215">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="216">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="217">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="218">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="219">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="220">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="221">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="222">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="223">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="224">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="225">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="226">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="227">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="228">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="229">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="230">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="231">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="232">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="233">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="234">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="235">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="236">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="237">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="238">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="239">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="240">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="241">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="242">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="243">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="244">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="245">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="246">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="247">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="248">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="249">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="250">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="251">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="252">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="253">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="254">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="255">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="256">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="257">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="258">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="259">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="260">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="261">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="262">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="263">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="264">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="265">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="266">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="267">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="268">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="269">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="270">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="271">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="272">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="273">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="274">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="275">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="276">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="277">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="278">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="279">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="280">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="281">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="282">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="283">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="284">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="285">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="286">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="287">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="288">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="289">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="290">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="291">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="292">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="293">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="294">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="295">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="296">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="297">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="298">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="299">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="300">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="301">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="302">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="303">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="304">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="305">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_common_name>Human</PDBx:gene_src_common_name>
         <PDBx:host_org_common_name>fall armyworm</PDBx:host_org_common_name>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_beg_seq_num>1</PDBx:pdbx_beg_seq_num>
         <PDBx:pdbx_end_seq_num>305</PDBx:pdbx_end_seq_num>
         <PDBx:pdbx_gene_src_gene>TGFBR1, ALK5, SKR4</PDBx:pdbx_gene_src_gene>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>9606</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Homo sapiens</PDBx:pdbx_gene_src_scientific_name>
         <PDBx:pdbx_host_org_ncbi_taxonomy_id>7108</PDBx:pdbx_host_org_ncbi_taxonomy_id>
         <PDBx:pdbx_host_org_scientific_name>Spodoptera frugiperda</PDBx:pdbx_host_org_scientific_name>
         <PDBx:pdbx_seq_type>Biological sequence</PDBx:pdbx_seq_type>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="4X0M"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="4X0M" method="X-RAY DIFFRACTION">
         <PDBx:crystals_number>1</PDBx:crystals_number>
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>2.07</PDBx:density_Matthews>
         <PDBx:density_percent_sol>40.66</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:exptl_crystal_growCategory>
      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>VAPOR DIFFUSION, HANGING DROP</PDBx:method>
         <PDBx:pdbx_details>0.1 M Tris-HCl, 240 mM Li2SO4, 24&#37; PEG 4000, pH 7.5</PDBx:pdbx_details>
         <PDBx:pdbx_pH_range>7.5</PDBx:pdbx_pH_range>
         <PDBx:temp>293</PDBx:temp>
      </PDBx:exptl_crystal_grow>
   </PDBx:exptl_crystal_growCategory>
   <PDBx:pdbx_audit_revision_detailsCategory>
      <PDBx:pdbx_audit_revision_details data_content_type="Structure model" ordinal="1" revision_ordinal="1">
         <PDBx:provider>repository</PDBx:provider>
         <PDBx:type>Initial release</PDBx:type>
      </PDBx:pdbx_audit_revision_details>
   </PDBx:pdbx_audit_revision_detailsCategory>
   <PDBx:pdbx_audit_revision_groupCategory>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="1" revision_ordinal="2">
         <PDBx:group>Database references</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
   </PDBx:pdbx_audit_revision_groupCategory>
   <PDBx:pdbx_audit_revision_historyCategory>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="1">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>0</PDBx:minor_revision>
         <PDBx:revision_date>2014-12-24</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="2">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>1</PDBx:minor_revision>
         <PDBx:revision_date>2015-01-21</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
   </PDBx:pdbx_audit_revision_historyCategory>
   <PDBx:pdbx_database_relatedCategory>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="1vjy" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="4X0M">
         <PDBx:SG_entry>N</PDBx:SG_entry>
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>PDBE</PDBx:process_site>
         <PDBx:recvd_initial_deposition_date>2014-11-21</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>3WA</PDBx:comp_id>
         <PDBx:name>4-aminopyrido[2,3-d]pyrimidin-5(8H)-one</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>SO4</PDBx:comp_id>
         <PDBx:name>SULFATE ION</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="4">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>INH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>3WA</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>3WA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>601</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>SO4</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>SO4</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SO4</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>602</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>120</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>701</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>116</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>702</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>42</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>703</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>52</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>704</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>151</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>705</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>158</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>706</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>98</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>707</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>73</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>708</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>33</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>709</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>84</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>710</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>65</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>711</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>156</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>712</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>159</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>713</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>56</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>714</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>64</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>715</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>60</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>716</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>19</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>717</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>119</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>718</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>75</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>719</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>57</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>720</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>51</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>721</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>50</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>722</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>92</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>723</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>79</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>724</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>725</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>726</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>67</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>727</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>138</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>728</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>166</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>729</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>171</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>730</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>28</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>731</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>15</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>732</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>25</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>733</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>27</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>734</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>100</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>735</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>736</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>41</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>737</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>44</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>738</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>114</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>739</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>143</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>740</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>81</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>741</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>101</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>742</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>150</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>743</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>744</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>83</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>745</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>106</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>746</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>58</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>747</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>31</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>748</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>43</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>749</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>26</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>750</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>170</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>751</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>90</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>752</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>23</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>753</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>141</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>754</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>132</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>755</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>128</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>756</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>107</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>757</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>17</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>758</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>88</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>759</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>162</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>760</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>38</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>761</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>85</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>762</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>164</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>763</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>160</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>764</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>105</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>765</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>133</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>766</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>110</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>767</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>145</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>768</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>165</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>769</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>97</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>770</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>147</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>771</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>59</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>772</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>129</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>773</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>774</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>775</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>776</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>777</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>778</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>779</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>780</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>781</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>782</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>14</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>783</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>784</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>18</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>785</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>20</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>786</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>21</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>787</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>22</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>788</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>24</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>789</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>29</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>790</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>30</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>791</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>32</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>792</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>34</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>793</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>35</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>794</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>795</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>37</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>796</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>39</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>797</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>40</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>798</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>45</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>799</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>46</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>800</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>47</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>801</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>48</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>802</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>49</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>803</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>53</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>804</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>54</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>805</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>55</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>806</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>61</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>807</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>62</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>808</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>63</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>809</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>66</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>810</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="111">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>68</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>811</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="112">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>69</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>812</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="113">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>70</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>813</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="114">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>71</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>814</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="115">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>72</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>815</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="116">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>74</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>816</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="117">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>76</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>817</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="118">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>77</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>818</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="119">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>78</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>819</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="120">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>80</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>820</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="121">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>82</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>821</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="122">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>86</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>822</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="123">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>87</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>823</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="124">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>89</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>824</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="125">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>91</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>825</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="126">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>93</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>826</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="127">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>94</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>827</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="128">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>95</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>828</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="129">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>96</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>829</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="130">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>99</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>830</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="131">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>102</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>831</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="132">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>103</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>832</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="133">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>104</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>833</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="134">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>108</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>834</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="135">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>109</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>835</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="136">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>111</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>836</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="137">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>112</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>837</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="138">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>113</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>838</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="139">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>115</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>839</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="140">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>117</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>840</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="141">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>118</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>841</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="142">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>121</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>842</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="143">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>122</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>843</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="144">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>123</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>844</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="145">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>124</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>845</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="146">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>125</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>846</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="147">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>126</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>847</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="148">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>127</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>848</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="149">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>130</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>849</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="150">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>131</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>850</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="151">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>134</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>851</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="152">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>135</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>852</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="153">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>136</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>853</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="154">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>137</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>854</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="155">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>139</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>855</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="156">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>140</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>856</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="157">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>142</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>857</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="158">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>144</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>858</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="159">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>146</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>859</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="160">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>148</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>860</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="161">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>149</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>861</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="162">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>152</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>862</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="163">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>153</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>863</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="164">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>154</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>864</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="165">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>155</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>865</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="166">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>157</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>866</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="167">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>161</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>867</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="168">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>163</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>868</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="169">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>167</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>869</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="170">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>168</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>870</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="171">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>169</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>871</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="172">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>172</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>872</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="173">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>173</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>873</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="1">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>199</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>199</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="2">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>200</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>200</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="3">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>201</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>201</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="4">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>202</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>202</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="5">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>203</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>203</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="6">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>204</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>204</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="7">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>205</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>205</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="8">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>206</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>206</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="9">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>207</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>207</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="10">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>208</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>208</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="11">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>209</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>209</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="12">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>210</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>210</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="13">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>211</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>211</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="14">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>212</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>212</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="15">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>213</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>213</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="16">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>214</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>214</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="17">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>215</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>215</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="18">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>216</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>216</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="19">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>217</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="20">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>218</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>218</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="21">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>219</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>219</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="22">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>220</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>220</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="23">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>221</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="24">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>222</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>222</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="25">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>223</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>223</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="26">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>224</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>224</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="27">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>225</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>225</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="28">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>226</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>226</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="29">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>227</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>227</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="30">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>228</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>228</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="31">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>229</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>229</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="32">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>230</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>230</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="33">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>231</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>231</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="34">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>232</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>232</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="35">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>233</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>233</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="36">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>234</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>234</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="37">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>235</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>235</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="38">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>236</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>236</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="39">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>237</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>237</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="40">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>238</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>238</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="41">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>239</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>239</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="42">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>240</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>240</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="43">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>241</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>241</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="44">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>242</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>242</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="45">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>243</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>243</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="46">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>244</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>244</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="47">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>245</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>245</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="48">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>246</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>246</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="49">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>247</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>247</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="50">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>248</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>248</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="51">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>249</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>249</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="52">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>250</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>250</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="53">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>251</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>251</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="54">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>252</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>252</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="55">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>253</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>253</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="56">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>254</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>254</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="57">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>255</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>255</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="58">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>256</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>256</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="59">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>257</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>257</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="60">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>258</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>258</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="61">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>259</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>259</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="62">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>260</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>260</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="63">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>261</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>261</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="64">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>262</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>262</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="65">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>263</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>263</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="66">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>264</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>264</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="67">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>265</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>265</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="68">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>266</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>266</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="69">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>267</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>267</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="70">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>268</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>268</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="71">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>269</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>269</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="72">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>270</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>270</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="73">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>271</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>271</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="74">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>272</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>272</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="75">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>273</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>273</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="76">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>274</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>274</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="77">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>275</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>275</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="78">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>276</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>276</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="79">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>277</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>277</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="80">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>278</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>278</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="81">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>279</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>279</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="82">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>280</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>280</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="83">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>281</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>281</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="84">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>282</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>282</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="85">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>283</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>283</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="86">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>284</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>284</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="87">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>285</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>285</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="88">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>286</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>286</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="89">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>287</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>287</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="90">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>288</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>288</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="91">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>289</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>289</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="92">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>290</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>290</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="93">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>291</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>291</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="94">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>292</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>292</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="95">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>293</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>293</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="96">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>294</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>294</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="97">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>295</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>295</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="98">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>296</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>296</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="99">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>297</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>297</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="100">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>298</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>298</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="101">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>299</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>299</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="102">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>300</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>300</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="103">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>301</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="104">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>302</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>302</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="105">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>303</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>303</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="106">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>304</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>304</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="107">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>305</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>305</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="108">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>306</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>306</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="109">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>307</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>307</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="110">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>308</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>308</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="111">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>309</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>309</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="112">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>310</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>310</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="113">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>311</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>311</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="114">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>312</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>312</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="115">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>313</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>313</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="116">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>314</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>314</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="117">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>315</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>315</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="118">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>316</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>316</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="119">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>317</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>317</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="120">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>318</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>318</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="121">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>319</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>319</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="122">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>320</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>320</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="123">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>321</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>321</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="124">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>322</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>322</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="125">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>323</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>323</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="126">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>324</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>324</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="127">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>325</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>325</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="128">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>326</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>326</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="129">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>327</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>327</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="130">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>328</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>328</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="131">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>329</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>329</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="132">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>330</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>330</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="133">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>331</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>331</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="134">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>332</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>332</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="135">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>333</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>333</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="136">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>334</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>334</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="137">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>335</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>335</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="138">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>336</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>336</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="139">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>337</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>337</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="140">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>338</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>338</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="141">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>339</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>339</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="142">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>340</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>340</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="143">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>341</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>341</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="144">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>342</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>342</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="145">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>343</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>343</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="146">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>344</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>344</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="147">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>345</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>345</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="148">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>346</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>346</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="149">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>347</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>347</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="150">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>348</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>348</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="151">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>349</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>349</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="152">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>350</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>350</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="153">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>351</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>351</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="154">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>352</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>352</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="155">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>353</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>353</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="156">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>354</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>354</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="157">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>355</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>355</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="158">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>356</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>356</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="159">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>357</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>357</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="160">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>358</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>358</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="161">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>359</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>359</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="162">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>360</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>360</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="163">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>361</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>361</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="164">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>362</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>362</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="165">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>363</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>363</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="166">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>364</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>364</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="167">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>365</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>365</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="168">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>366</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>366</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="169">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>367</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>367</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="170">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>368</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>368</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="171">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>369</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>369</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="172">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>370</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>370</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="173">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>371</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="174">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>372</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="175">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>373</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="176">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>374</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="177">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>375</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="178">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>376</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="179">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>377</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="180">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>378</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="181">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>379</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="182">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>380</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="183">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="184">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="185">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="186">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="187">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="188">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="189">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="190">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="191">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="192">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>192</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="193">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>193</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="194">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>194</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="195">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>195</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="196">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="197">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="198">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>198</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="199">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>199</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="200">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>200</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="201">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>201</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="202">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>202</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="203">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>203</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="204">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>204</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="205">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>205</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="206">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>206</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="207">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>207</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="208">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>208</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="209">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>209</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="210">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>210</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="211">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>211</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="212">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>212</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="213">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>213</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="214">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>214</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="215">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>215</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="216">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>216</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="217">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>217</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="218">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>218</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="219">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>219</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="220">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>220</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="221">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>221</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="222">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>222</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="223">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>223</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="224">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>224</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="225">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>225</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="226">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>226</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="227">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>227</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="228">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>228</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="229">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>229</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="230">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>230</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="231">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>231</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="232">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>232</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="233">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>233</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="234">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>234</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="235">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>235</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="236">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>236</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="237">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>237</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="238">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>238</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="239">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>239</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="240">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>240</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="241">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>241</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="242">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>242</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="243">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>243</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="244">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>244</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="245">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>245</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="246">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>246</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="247">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>247</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="248">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>248</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="249">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>249</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="250">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>250</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="251">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>251</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="252">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>252</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="253">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>253</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="254">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>254</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="255">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>255</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="256">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>256</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="257">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>455</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>257</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="258">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>456</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>258</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="259">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>457</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>259</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="260">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>458</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>260</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="261">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>459</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>261</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="262">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>460</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>262</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="263">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>461</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>263</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="264">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>462</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>264</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="265">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>463</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>265</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="266">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>464</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>266</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="267">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>465</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>267</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="268">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>466</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>268</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="269">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>467</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>269</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="270">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>468</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>270</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="271">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>469</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>271</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="272">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>470</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>272</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="273">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>471</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>273</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="274">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>472</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>274</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="275">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>473</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>275</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="276">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>474</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>276</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="277">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>475</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>277</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="278">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>476</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>278</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="279">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>477</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>279</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="280">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>478</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>280</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="281">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>479</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>281</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="282">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>480</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>282</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="283">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>481</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>283</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="284">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>482</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>284</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="285">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>483</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>285</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="286">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>484</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>286</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="287">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>485</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>287</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>485</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="288">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>486</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>288</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>486</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="289">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>487</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>289</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>487</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="290">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>488</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>290</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>488</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="291">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>489</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>291</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>489</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="292">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>490</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>292</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>490</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="293">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>491</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>293</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>491</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="294">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>492</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>294</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>492</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="295">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>493</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>295</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>493</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="296">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>494</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>296</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>494</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="297">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>495</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>297</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>495</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="298">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>496</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>298</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>496</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="299">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>497</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>299</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>497</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="300">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>498</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>300</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>498</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="301">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>499</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>301</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>499</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="302">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>500</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>302</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>500</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="303">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>501</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>303</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="304">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>304</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="305">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>305</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_refine_tlsCategory>
      <PDBx:pdbx_refine_tls id="1">
         <PDBx:L11>0.2970</PDBx:L11>
         <PDBx:L12>0.3171</PDBx:L12>
         <PDBx:L13>0.1794</PDBx:L13>
         <PDBx:L22>0.4810</PDBx:L22>
         <PDBx:L23>0.5220</PDBx:L23>
         <PDBx:L33>0.5836</PDBx:L33>
         <PDBx:S11>-0.0015</PDBx:S11>
         <PDBx:S12>-0.0153</PDBx:S12>
         <PDBx:S13>0.0537</PDBx:S13>
         <PDBx:S21>-0.0316</PDBx:S21>
         <PDBx:S22>0.0002</PDBx:S22>
         <PDBx:S23>0.0356</PDBx:S23>
         <PDBx:S31>-0.0440</PDBx:S31>
         <PDBx:S32>0.0011</PDBx:S32>
         <PDBx:S33>0.0013</PDBx:S33>
         <PDBx:T11>0.0182</PDBx:T11>
         <PDBx:T12>0.0001</PDBx:T12>
         <PDBx:T13>0.0052</PDBx:T13>
         <PDBx:T22>-0.0058</PDBx:T22>
         <PDBx:T23>0.0018</PDBx:T23>
         <PDBx:T33>-0.1378</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>12.0520</PDBx:origin_x>
         <PDBx:origin_y>75.8878</PDBx:origin_y>
         <PDBx:origin_z>12.3086</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
   </PDBx:pdbx_refine_tlsCategory>
   <PDBx:pdbx_refine_tls_groupCategory>
      <PDBx:pdbx_refine_tls_group id="1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>199</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>501</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
         <PDBx:selection_details>{ A|* }</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
   </PDBx:pdbx_refine_tls_groupCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_and_software_defined_assembly</PDBx:details>
         <PDBx:method_details>PISA</PDBx:method_details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_assembly_propCategory>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="ABSA (A^2)">
         <PDBx:value>230</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="MORE">
         <PDBx:value>-17</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="SSA (A^2)">
         <PDBx:value>14350</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
   </PDBx:pdbx_struct_assembly_propCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>GLU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>209</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>GLU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>11</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ARG</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>221</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ARG</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>23</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>GLY</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>222</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>GLY</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>24</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>VAL</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>229</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>VAL</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>31</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="3" range_id_2="4" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LYS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>232</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LYS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>34</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>278</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>80</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="4" range_id_2="5" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>TRP</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>277</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>TRP</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>79</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ASP</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>266</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ASP</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>68</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ALA</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>330</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ALA</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>132</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>VAL</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>356</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>VAL</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>158</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="AA2">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ASP</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>359</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ASP</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>161</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>THR</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>364</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>THR</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>166</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA3">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>340</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>142</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>CYS</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>348</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>CYS</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>150</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>304</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>305</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
   </PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>263</PDBx:auth_seq_id>
         <PDBx:phi>-102.07</PDBx:phi>
         <PDBx:psi>-62.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>324</PDBx:auth_seq_id>
         <PDBx:phi>-103.77</PDBx:phi>
         <PDBx:psi>46.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>332</PDBx:auth_seq_id>
         <PDBx:phi>74.03</PDBx:phi>
         <PDBx:psi>-11.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>333</PDBx:auth_seq_id>
         <PDBx:phi>-141.56</PDBx:phi>
         <PDBx:psi>45.21</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>368</PDBx:auth_seq_id>
         <PDBx:phi>33.42</PDBx:phi>
         <PDBx:psi>70.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:pdbx_xplor_fileCategory>
      <PDBx:pdbx_xplor_file pdbx_refine_id="X-RAY DIFFRACTION" serial_no="1">
         <PDBx:param_file>protein_rep.param</PDBx:param_file>
      </PDBx:pdbx_xplor_file>
      <PDBx:pdbx_xplor_file pdbx_refine_id="X-RAY DIFFRACTION" serial_no="2">
         <PDBx:param_file>adp.par</PDBx:param_file>
      </PDBx:pdbx_xplor_file>
      <PDBx:pdbx_xplor_file pdbx_refine_id="X-RAY DIFFRACTION" serial_no="3">
         <PDBx:param_file>water_rep.param</PDBx:param_file>
      </PDBx:pdbx_xplor_file>
      <PDBx:pdbx_xplor_file pdbx_refine_id="X-RAY DIFFRACTION" serial_no="4">
         <PDBx:param_file>ion.param</PDBx:param_file>
      </PDBx:pdbx_xplor_file>
      <PDBx:pdbx_xplor_file pdbx_refine_id="X-RAY DIFFRACTION" serial_no="5">
         <PDBx:param_file>emd.par</PDBx:param_file>
      </PDBx:pdbx_xplor_file>
   </PDBx:pdbx_xplor_fileCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="4X0M" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_max>85.820</PDBx:B_iso_max>
         <PDBx:B_iso_mean>15.6100</PDBx:B_iso_mean>
         <PDBx:B_iso_min>3.340</PDBx:B_iso_min>
         <PDBx:aniso_B11>2.9072</PDBx:aniso_B11>
         <PDBx:aniso_B12>0.0000</PDBx:aniso_B12>
         <PDBx:aniso_B13>0.0000</PDBx:aniso_B13>
         <PDBx:aniso_B22>-2.0366</PDBx:aniso_B22>
         <PDBx:aniso_B23>0.0000</PDBx:aniso_B23>
         <PDBx:aniso_B33>-0.8707</PDBx:aniso_B33>
         <PDBx:correlation_coeff_Fo_to_Fc>0.9183</PDBx:correlation_coeff_Fo_to_Fc>
         <PDBx:correlation_coeff_Fo_to_Fc_free>0.8827</PDBx:correlation_coeff_Fo_to_Fc_free>
         <PDBx:ls_R_factor_R_free>0.2393</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.1839</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.2098</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.6800</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>38.6900</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>13989</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_R_work>15375</PDBx:ls_number_reflns_R_work>
         <PDBx:ls_number_reflns_obs>29363</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>47.6400</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>86.8300</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_R_Cruickshank_DPI>0.1210</PDBx:overall_SU_R_Cruickshank_DPI>
         <PDBx:pdbx_R_Free_selection_details>RANDOM</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>THROUGHOUT</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>0.000</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_SU_R_Blow_DPI>0.1250</PDBx:pdbx_overall_SU_R_Blow_DPI>
         <PDBx:pdbx_overall_SU_R_free_Blow_DPI>0.1280</PDBx:pdbx_overall_SU_R_free_Blow_DPI>
         <PDBx:pdbx_overall_SU_R_free_Cruickshank_DPI>0.1260</PDBx:pdbx_overall_SU_R_free_Cruickshank_DPI>
         <PDBx:pdbx_starting_model>1vjy</PDBx:pdbx_starting_model>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_analyzeCategory>
      <PDBx:refine_analyze entry_id="4X0M" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:Luzzati_coordinate_error_obs>0.220</PDBx:Luzzati_coordinate_error_obs>
      </PDBx:refine_analyze>
   </PDBx:refine_analyzeCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="final" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.6800</PDBx:d_res_high>
         <PDBx:d_res_low>38.6900</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>173</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>2619</PDBx:number_atoms_total>
         <PDBx:pdbx_B_iso_mean_ligand>16.47</PDBx:pdbx_B_iso_mean_ligand>
         <PDBx:pdbx_B_iso_mean_solvent>20.16</PDBx:pdbx_B_iso_mean_solvent>
         <PDBx:pdbx_number_atoms_ligand>17</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>2429</PDBx:pdbx_number_atoms_protein>
         <PDBx:pdbx_number_residues_total>303</PDBx:pdbx_number_residues_total>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="c_mcbond_it">
         <PDBx:dev_ideal>1.326</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.500</PDBx:dev_ideal_target>
         <PDBx:pdbx_restraint_function>SINUSOIDAL</PDBx:pdbx_restraint_function>
         <PDBx:weight>2.000</PDBx:weight>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="c_scbond_it">
         <PDBx:dev_ideal>2.133</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>2.000</PDBx:dev_ideal_target>
         <PDBx:pdbx_restraint_function>HARMONIC</PDBx:pdbx_restraint_function>
         <PDBx:weight>2.000</PDBx:weight>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="c_mcangle_it">
         <PDBx:dev_ideal>1.935</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>2.000</PDBx:dev_ideal_target>
         <PDBx:pdbx_restraint_function>HARMONIC</PDBx:pdbx_restraint_function>
         <PDBx:weight>5.000</PDBx:weight>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="c_scangle_it">
         <PDBx:dev_ideal>2.928</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>2.500</PDBx:dev_ideal_target>
         <PDBx:pdbx_restraint_function>HARMONIC</PDBx:pdbx_restraint_function>
         <PDBx:weight>20.000</PDBx:weight>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.6800" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.3142</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_work>0.1967</PDBx:R_factor_R_work>
         <PDBx:R_factor_all>0.2553</PDBx:R_factor_all>
         <PDBx:d_res_low>1.7400</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>1032</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>930</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>1962</PDBx:number_reflns_all>
         <PDBx:pdbx_total_number_of_bins_used>15</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free>52.6000</PDBx:percent_reflns_R_free>
         <PDBx:percent_reflns_obs>86.8300</PDBx:percent_reflns_obs>
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:B_iso_Wilson_estimate>12.850</PDBx:B_iso_Wilson_estimate>
         <PDBx:Rmerge_F_obs>0.179</PDBx:Rmerge_F_obs>
         <PDBx:d_resolution_high>1.680</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>38.7</PDBx:d_resolution_low>
         <PDBx:entry_id>4X0M</PDBx:entry_id>
         <PDBx:number_obs>32312</PDBx:number_obs>
         <PDBx:observed_criterion_sigma_I>-3.000</PDBx:observed_criterion_sigma_I>
         <PDBx:pdbx_Rmerge_I_obs>0.185</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_Rrim_I_all>0.218</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.247</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>9.220</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_number_measured_all>102541</PDBx:pdbx_number_measured_all>
         <PDBx:pdbx_redundancy>3.2</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>95.300</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_F_obs>0.397</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.429</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.680</PDBx:d_res_high>
         <PDBx:d_res_low>1.780</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>4.200</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>13178</PDBx:number_measured_obs>
         <PDBx:number_possible>5378</PDBx:number_possible>
         <PDBx:number_unique_obs>4546</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.514</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>84.500</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="2">
         <PDBx:Rmerge_F_obs>0.365</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.424</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.780</PDBx:d_res_high>
         <PDBx:d_res_low>1.900</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>5.510</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>15992</PDBx:number_measured_obs>
         <PDBx:number_possible>5085</PDBx:number_possible>
         <PDBx:number_unique_obs>5021</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.500</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.700</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="3">
         <PDBx:Rmerge_F_obs>0.279</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.367</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.900</PDBx:d_res_high>
         <PDBx:d_res_low>2.050</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>7.180</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>14979</PDBx:number_measured_obs>
         <PDBx:number_possible>4717</PDBx:number_possible>
         <PDBx:number_unique_obs>4641</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.431</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.400</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="4">
         <PDBx:Rmerge_F_obs>0.195</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.280</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.050</PDBx:d_res_high>
         <PDBx:d_res_low>2.250</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>9.000</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>14030</PDBx:number_measured_obs>
         <PDBx:number_possible>4382</PDBx:number_possible>
         <PDBx:number_unique_obs>4320</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.327</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="5">
         <PDBx:Rmerge_F_obs>0.162</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.227</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.250</PDBx:d_res_high>
         <PDBx:d_res_low>2.510</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>10.160</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>12935</PDBx:number_measured_obs>
         <PDBx:number_possible>3974</PDBx:number_possible>
         <PDBx:number_unique_obs>3890</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.265</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>97.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="6">
         <PDBx:Rmerge_F_obs>0.140</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.189</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.510</PDBx:d_res_high>
         <PDBx:d_res_low>2.900</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>11.470</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>11069</PDBx:number_measured_obs>
         <PDBx:number_possible>3539</PDBx:number_possible>
         <PDBx:number_unique_obs>3404</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.220</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>96.200</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="7">
         <PDBx:Rmerge_F_obs>0.100</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.128</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.900</PDBx:d_res_high>
         <PDBx:d_res_low>3.550</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>13.520</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>9077</PDBx:number_measured_obs>
         <PDBx:number_possible>3020</PDBx:number_possible>
         <PDBx:number_unique_obs>2892</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.151</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>95.800</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="8">
         <PDBx:Rmerge_F_obs>0.063</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.078</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.550</PDBx:d_res_high>
         <PDBx:d_res_low>5.000</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>16.780</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>7185</PDBx:number_measured_obs>
         <PDBx:number_possible>2387</PDBx:number_possible>
         <PDBx:number_unique_obs>2261</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.094</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>94.700</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="9">
         <PDBx:Rmerge_F_obs>0.049</PDBx:Rmerge_F_obs>
         <PDBx:Rmerge_I_obs>0.061</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>5.000</PDBx:d_res_high>
         <PDBx:meanI_over_sigI_obs>17.500</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>4096</PDBx:number_measured_obs>
         <PDBx:number_possible>1422</PDBx:number_possible>
         <PDBx:number_unique_obs>1337</PDBx:number_unique_obs>
         <PDBx:pdbx_Rrim_I_all>0.073</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>94.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:name>XSCALE</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>BUSTER</PDBx:name>
         <PDBx:version>2.11.4</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>data extraction</PDBx:classification>
         <PDBx:name>PDB_EXTRACT</PDBx:name>
         <PDBx:version>3.15</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:name>XDS</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="5">
         <PDBx:classification>phasing</PDBx:classification>
         <PDBx:name>MOLREP</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="4X0M">
         <PDBx:pdbx_descriptor>TGF-beta receptor type I (E.C.2.7.1.37)</PDBx:pdbx_descriptor>
         <PDBx:title>Selection of fragments for kinase inhibitor design: decoration is key</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>201</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>3</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>203</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>5</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>3</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>238</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>40</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>250</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>52</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>13</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>287</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>89</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TYR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>295</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TYR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>97</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>9</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>298</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>100</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>MET</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>318</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>MET</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>120</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>21</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P5">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>351</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>153</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>355</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>157</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P6">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>375</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>177</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>MET</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>379</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>MET</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>181</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P7">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ALA</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>380</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ALA</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>182</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>385</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>187</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA7</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P8">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>392</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>194</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>414</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>216</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA8</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>23</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P9">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>437</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>239</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>CYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>446</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>CYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>248</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA9</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>10</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P10">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>455</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>257</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>459</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>261</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P11">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>CYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>461</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>CYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>263</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>473</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>275</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>13</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P12">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>478</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>280</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>482</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>284</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P13">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>484</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>286</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>500</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>302</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>17</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="4X0M">
         <PDBx:pdbx_keywords>TRANSFERASE</PDBx:pdbx_keywords>
         <PDBx:text>TRANSFERASE, PROTEIN KINASE, INHIBITOR COMPLEX</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>TGFR1_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>200</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P36897</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>TIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLV
SDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHD
SATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVE
EMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>200</PDBx:db_align_beg>
         <PDBx:db_align_end>503</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4X0M</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>200</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>503</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P36897</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>2</PDBx:seq_align_beg>
         <PDBx:seq_align_end>305</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>expression tag</PDBx:details>
         <PDBx:mon_id>GLY</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>199</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4X0M</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P36897</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>1</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="AA1">
         <PDBx:number_strands>5</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA2">
         <PDBx:number_strands>3</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA3">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="4" range_id_2="5" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="AA2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA3">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>205</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>7</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>213</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>15</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>218</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>20</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TRP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>224</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TRP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>26</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>227</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>29</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>235</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>37</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>274</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>76</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>281</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>83</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="5" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PHE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>262</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PHE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>64</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>269</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>71</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>329</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>131</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>330</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>132</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>356</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>158</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>359</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>161</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>364</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>166</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>365</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>167</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>339</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>141</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>341</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>143</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>CYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>347</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>CYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>149</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>349</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>151</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>binding site for residue 3WA A 601</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>3WA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>9</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>binding site for residue SO4 A 602</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>SO4</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>7</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>211</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>13</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>230</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>32</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>62</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>280</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>82</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>281</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>83</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>282</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>84</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>283</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>85</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>340</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>142</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>861</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>9</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>337</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>139</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>179</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>435</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>237</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>436</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>238</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>710</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>787</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>806</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="4X0M">
         <PDBx:Int_Tables_number>19</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 21 21 21</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
