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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_atom_id>OG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>197</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1711">
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>342</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>197</PDBx:label_seq_id>
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      <PDBx:atom_site id="1712">
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="1713">
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1714">
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1715">
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         <PDBx:Cartn_y>8.39991</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.52439</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1716">
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         <PDBx:Cartn_x>12.40851</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.84711</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.42070</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1717">
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         <PDBx:Cartn_x>14.20035</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.23145</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.83801</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1718">
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         <PDBx:Cartn_x>12.96147</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.01519</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.32268</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1719">
         <PDBx:B_iso_or_equiv>26.00907</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.81079</PDBx:Cartn_x>
         <PDBx:Cartn_y>7.24455</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.41477</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1720">
         <PDBx:B_iso_or_equiv>31.21351</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.21776</PDBx:Cartn_x>
         <PDBx:Cartn_y>6.64553</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.57813</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1721">
         <PDBx:B_iso_or_equiv>35.51896</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.50450</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.30572</PDBx:Cartn_y>
         <PDBx:Cartn_z>3.31032</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1722">
         <PDBx:B_iso_or_equiv>35.05816</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.55002</PDBx:Cartn_x>
         <PDBx:Cartn_y>5.97228</PDBx:Cartn_y>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1723">
         <PDBx:B_iso_or_equiv>39.53677</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.03047</PDBx:Cartn_x>
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         <PDBx:Cartn_z>2.95481</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1724">
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         <PDBx:Cartn_z>7.65368</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1725">
         <PDBx:B_iso_or_equiv>48.39662</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.78507</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.62458</PDBx:Cartn_y>
         <PDBx:Cartn_z>1.46309</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>198</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1726">
         <PDBx:B_iso_or_equiv>28.97604</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>5.07644</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.53924</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
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         <PDBx:auth_seq_id>344</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>201</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_x>10.19523</PDBx:Cartn_x>
         <PDBx:Cartn_y>6.03414</PDBx:Cartn_y>
         <PDBx:Cartn_z>2.99158</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>201</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1796">
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         <PDBx:Cartn_y>4.06828</PDBx:Cartn_y>
         <PDBx:Cartn_z>1.10571</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>201</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1797">
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         <PDBx:Cartn_z>1.72397</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>201</PDBx:label_seq_id>
         <PDBx:occupancy>0.423</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1798">
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         <PDBx:Cartn_z>-0.43627</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>201</PDBx:label_seq_id>
         <PDBx:occupancy>0.577</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1799">
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         <PDBx:Cartn_z>3.68732</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>201</PDBx:label_seq_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1800">
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1801">
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>4.81291</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
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         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1804">
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         <PDBx:Cartn_z>3.28216</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
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         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1805">
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         <PDBx:Cartn_z>3.31149</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="4">
         <PDBx:U11>0.58774</PDBx:U11>
         <PDBx:U12>0.25330</PDBx:U12>
         <PDBx:U13>-0.16853</PDBx:U13>
         <PDBx:U22>0.54076</PDBx:U22>
         <PDBx:U23>-0.08762</PDBx:U23>
         <PDBx:U33>0.61804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>0</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="5">
         <PDBx:U11>0.67294</PDBx:U11>
         <PDBx:U12>0.22582</PDBx:U12>
         <PDBx:U13>-0.18254</PDBx:U13>
         <PDBx:U22>0.61096</PDBx:U22>
         <PDBx:U23>-0.07201</PDBx:U23>
         <PDBx:U33>0.68150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>0</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="6">
         <PDBx:U11>0.66833</PDBx:U11>
         <PDBx:U12>0.21473</PDBx:U12>
         <PDBx:U13>-0.17595</PDBx:U13>
         <PDBx:U22>0.62839</PDBx:U22>
         <PDBx:U23>-0.06739</PDBx:U23>
         <PDBx:U33>0.68881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>0</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="7">
         <PDBx:U11>0.67413</PDBx:U11>
         <PDBx:U12>0.21090</PDBx:U12>
         <PDBx:U13>-0.15490</PDBx:U13>
         <PDBx:U22>0.66756</PDBx:U22>
         <PDBx:U23>-0.06909</PDBx:U23>
         <PDBx:U33>0.71341</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>0</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="8">
         <PDBx:U11>0.43625</PDBx:U11>
         <PDBx:U12>0.20743</PDBx:U12>
         <PDBx:U13>-0.14803</PDBx:U13>
         <PDBx:U22>0.40594</PDBx:U22>
         <PDBx:U23>-0.07241</PDBx:U23>
         <PDBx:U33>0.44472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>0</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="9">
         <PDBx:U11>0.85565</PDBx:U11>
         <PDBx:U12>0.25404</PDBx:U12>
         <PDBx:U13>-0.19519</PDBx:U13>
         <PDBx:U22>0.76163</PDBx:U22>
         <PDBx:U23>-0.08235</PDBx:U23>
         <PDBx:U33>0.85732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="10">
         <PDBx:U11>1.01387</PDBx:U11>
         <PDBx:U12>0.26182</PDBx:U12>
         <PDBx:U13>-0.19661</PDBx:U13>
         <PDBx:U22>0.89600</PDBx:U22>
         <PDBx:U23>-0.08767</PDBx:U23>
         <PDBx:U33>0.99865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="11">
         <PDBx:U11>0.89383</PDBx:U11>
         <PDBx:U12>0.27722</PDBx:U12>
         <PDBx:U13>-0.19003</PDBx:U13>
         <PDBx:U22>0.79643</PDBx:U22>
         <PDBx:U23>-0.09454</PDBx:U23>
         <PDBx:U33>0.90481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="12">
         <PDBx:U11>1.00102</PDBx:U11>
         <PDBx:U12>0.28162</PDBx:U12>
         <PDBx:U13>-0.18388</PDBx:U13>
         <PDBx:U22>0.89466</PDBx:U22>
         <PDBx:U23>-0.10042</PDBx:U23>
         <PDBx:U33>1.00244</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="13">
         <PDBx:U11>1.22087</PDBx:U11>
         <PDBx:U12>0.26480</PDBx:U12>
         <PDBx:U13>-0.21447</PDBx:U13>
         <PDBx:U22>1.06561</PDBx:U22>
         <PDBx:U23>-0.08492</PDBx:U23>
         <PDBx:U33>1.18319</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="14">
         <PDBx:U11>1.40847</PDBx:U11>
         <PDBx:U12>0.27564</PDBx:U12>
         <PDBx:U13>-0.21864</PDBx:U13>
         <PDBx:U22>1.22834</PDBx:U22>
         <PDBx:U23>-0.09002</PDBx:U23>
         <PDBx:U33>1.35804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="15">
         <PDBx:U11>1.44972</PDBx:U11>
         <PDBx:U12>0.27273</PDBx:U12>
         <PDBx:U13>-0.21044</PDBx:U13>
         <PDBx:U22>1.25749</PDBx:U22>
         <PDBx:U23>-0.09434</PDBx:U23>
         <PDBx:U33>1.38123</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="16">
         <PDBx:U11>1.48978</PDBx:U11>
         <PDBx:U12>0.28959</PDBx:U12>
         <PDBx:U13>-0.23074</PDBx:U13>
         <PDBx:U22>1.29341</PDBx:U22>
         <PDBx:U23>-0.09129</PDBx:U23>
         <PDBx:U33>1.44180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="17">
         <PDBx:U11>1.49126</PDBx:U11>
         <PDBx:U12>0.28401</PDBx:U12>
         <PDBx:U13>-0.21686</PDBx:U13>
         <PDBx:U22>1.27582</PDBx:U22>
         <PDBx:U23>-0.09837</PDBx:U23>
         <PDBx:U33>1.41425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="18">
         <PDBx:U11>1.51623</PDBx:U11>
         <PDBx:U12>0.29465</PDBx:U12>
         <PDBx:U13>-0.22895</PDBx:U13>
         <PDBx:U22>1.29746</PDBx:U22>
         <PDBx:U23>-0.09656</PDBx:U23>
         <PDBx:U33>1.45150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="19">
         <PDBx:U11>0.71177</PDBx:U11>
         <PDBx:U12>0.28544</PDBx:U12>
         <PDBx:U13>-0.19081</PDBx:U13>
         <PDBx:U22>0.64224</PDBx:U22>
         <PDBx:U23>-0.09409</PDBx:U23>
         <PDBx:U33>0.75622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.09404</PDBx:U23>
         <PDBx:U33>0.75591</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.64979</PDBx:U11>
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         <PDBx:U13>-0.18576</PDBx:U13>
         <PDBx:U22>0.59799</PDBx:U22>
         <PDBx:U23>-0.10052</PDBx:U23>
         <PDBx:U33>0.72110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.18582</PDBx:U13>
         <PDBx:U22>0.59898</PDBx:U22>
         <PDBx:U23>-0.10036</PDBx:U23>
         <PDBx:U33>0.72199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.16597</PDBx:U13>
         <PDBx:U22>0.62702</PDBx:U22>
         <PDBx:U23>-0.10521</PDBx:U23>
         <PDBx:U33>0.73688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.16603</PDBx:U13>
         <PDBx:U22>0.62526</PDBx:U22>
         <PDBx:U23>-0.10518</PDBx:U23>
         <PDBx:U33>0.73515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.15916</PDBx:U13>
         <PDBx:U22>0.67632</PDBx:U22>
         <PDBx:U23>-0.11206</PDBx:U23>
         <PDBx:U33>0.79253</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="26">
         <PDBx:U11>0.68577</PDBx:U11>
         <PDBx:U12>0.31391</PDBx:U12>
         <PDBx:U13>-0.15931</PDBx:U13>
         <PDBx:U22>0.67254</PDBx:U22>
         <PDBx:U23>-0.11206</PDBx:U23>
         <PDBx:U33>0.78884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="27">
         <PDBx:U11>0.60663</PDBx:U11>
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         <PDBx:U13>-0.19434</PDBx:U13>
         <PDBx:U22>0.57539</PDBx:U22>
         <PDBx:U23>-0.09782</PDBx:U23>
         <PDBx:U33>0.71003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="28">
         <PDBx:U11>0.60441</PDBx:U11>
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         <PDBx:U13>-0.19408</PDBx:U13>
         <PDBx:U22>0.57479</PDBx:U22>
         <PDBx:U23>-0.09749</PDBx:U23>
         <PDBx:U33>0.70868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="29">
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         <PDBx:U13>-0.21519</PDBx:U13>
         <PDBx:U22>0.56541</PDBx:U22>
         <PDBx:U23>-0.09219</PDBx:U23>
         <PDBx:U33>0.71256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="30">
         <PDBx:U11>0.62325</PDBx:U11>
         <PDBx:U12>0.31507</PDBx:U12>
         <PDBx:U13>-0.21514</PDBx:U13>
         <PDBx:U22>0.57075</PDBx:U22>
         <PDBx:U23>-0.09274</PDBx:U23>
         <PDBx:U33>0.71966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="31">
         <PDBx:U11>0.62994</PDBx:U11>
         <PDBx:U12>0.32304</PDBx:U12>
         <PDBx:U13>-0.22242</PDBx:U13>
         <PDBx:U22>0.60118</PDBx:U22>
         <PDBx:U23>-0.09017</PDBx:U23>
         <PDBx:U33>0.75820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="32">
         <PDBx:U11>0.61139</PDBx:U11>
         <PDBx:U12>0.29909</PDBx:U12>
         <PDBx:U13>-0.22324</PDBx:U13>
         <PDBx:U22>0.54723</PDBx:U22>
         <PDBx:U23>-0.08497</PDBx:U23>
         <PDBx:U33>0.68772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="33">
         <PDBx:U11>0.65939</PDBx:U11>
         <PDBx:U12>0.32105</PDBx:U12>
         <PDBx:U13>-0.22504</PDBx:U13>
         <PDBx:U22>0.56418</PDBx:U22>
         <PDBx:U23>-0.09491</PDBx:U23>
         <PDBx:U33>0.72559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="34">
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         <PDBx:U12>0.32924</PDBx:U12>
         <PDBx:U13>-0.22015</PDBx:U13>
         <PDBx:U22>0.61078</PDBx:U22>
         <PDBx:U23>-0.09280</PDBx:U23>
         <PDBx:U33>0.77180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.52393</PDBx:U11>
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         <PDBx:U13>-0.15629</PDBx:U13>
         <PDBx:U22>0.51476</PDBx:U22>
         <PDBx:U23>-0.10178</PDBx:U23>
         <PDBx:U33>0.60708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>150</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="69">
         <PDBx:U11>0.53358</PDBx:U11>
         <PDBx:U12>0.31037</PDBx:U12>
         <PDBx:U13>-0.07324</PDBx:U13>
         <PDBx:U22>0.56978</PDBx:U22>
         <PDBx:U23>-0.14495</PDBx:U23>
         <PDBx:U33>0.61412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="70">
         <PDBx:U11>0.51003</PDBx:U11>
         <PDBx:U12>0.30347</PDBx:U12>
         <PDBx:U13>-0.05559</PDBx:U13>
         <PDBx:U22>0.57648</PDBx:U22>
         <PDBx:U23>-0.14453</PDBx:U23>
         <PDBx:U33>0.60095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="71">
         <PDBx:U11>0.49421</PDBx:U11>
         <PDBx:U12>0.29280</PDBx:U12>
         <PDBx:U13>-0.05135</PDBx:U13>
         <PDBx:U22>0.55735</PDBx:U22>
         <PDBx:U23>-0.14268</PDBx:U23>
         <PDBx:U33>0.56396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="72">
         <PDBx:U11>0.51546</PDBx:U11>
         <PDBx:U12>0.30064</PDBx:U12>
         <PDBx:U13>-0.08669</PDBx:U13>
         <PDBx:U22>0.54759</PDBx:U22>
         <PDBx:U23>-0.13438</PDBx:U23>
         <PDBx:U33>0.59544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="73">
         <PDBx:U11>0.63906</PDBx:U11>
         <PDBx:U12>0.30896</PDBx:U12>
         <PDBx:U13>-0.10395</PDBx:U13>
         <PDBx:U22>0.64715</PDBx:U22>
         <PDBx:U23>-0.13377</PDBx:U23>
         <PDBx:U33>0.71651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="74">
         <PDBx:U11>0.65251</PDBx:U11>
         <PDBx:U12>0.32315</PDBx:U12>
         <PDBx:U13>-0.10596</PDBx:U13>
         <PDBx:U22>0.64774</PDBx:U22>
         <PDBx:U23>-0.14110</PDBx:U23>
         <PDBx:U33>0.73151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="75">
         <PDBx:U11>0.61844</PDBx:U11>
         <PDBx:U12>0.30131</PDBx:U12>
         <PDBx:U13>-0.11547</PDBx:U13>
         <PDBx:U22>0.61950</PDBx:U22>
         <PDBx:U23>-0.12587</PDBx:U23>
         <PDBx:U33>0.69170</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="76">
         <PDBx:U11>0.50912</PDBx:U11>
         <PDBx:U12>0.30952</PDBx:U12>
         <PDBx:U13>-0.04546</PDBx:U13>
         <PDBx:U22>0.60531</PDBx:U22>
         <PDBx:U23>-0.14570</PDBx:U23>
         <PDBx:U33>0.63328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="77">
         <PDBx:U11>0.48909</PDBx:U11>
         <PDBx:U12>0.30268</PDBx:U12>
         <PDBx:U13>-0.02842</PDBx:U13>
         <PDBx:U22>0.61503</PDBx:U22>
         <PDBx:U23>-0.14429</PDBx:U23>
         <PDBx:U33>0.62607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="78">
         <PDBx:U11>0.48781</PDBx:U11>
         <PDBx:U12>0.29530</PDBx:U12>
         <PDBx:U13>-0.03053</PDBx:U13>
         <PDBx:U22>0.63660</PDBx:U22>
         <PDBx:U23>-0.13462</PDBx:U23>
         <PDBx:U33>0.65022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="79">
         <PDBx:U11>0.47307</PDBx:U11>
         <PDBx:U12>0.30307</PDBx:U12>
         <PDBx:U13>-0.03670</PDBx:U13>
         <PDBx:U22>0.63082</PDBx:U22>
         <PDBx:U23>-0.13357</PDBx:U23>
         <PDBx:U33>0.66104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="80">
         <PDBx:U11>0.51095</PDBx:U11>
         <PDBx:U12>0.31472</PDBx:U12>
         <PDBx:U13>-0.01157</PDBx:U13>
         <PDBx:U22>0.65350</PDBx:U22>
         <PDBx:U23>-0.15431</PDBx:U23>
         <PDBx:U33>0.66520</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="81">
         <PDBx:U11>0.49252</PDBx:U11>
         <PDBx:U12>0.30703</PDBx:U12>
         <PDBx:U13>0.00632</PDBx:U13>
         <PDBx:U22>0.66646</PDBx:U22>
         <PDBx:U23>-0.15190</PDBx:U23>
         <PDBx:U33>0.66166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="82">
         <PDBx:U11>0.53587</PDBx:U11>
         <PDBx:U12>0.32041</PDBx:U12>
         <PDBx:U13>-0.00890</PDBx:U13>
         <PDBx:U22>0.65424</PDBx:U22>
         <PDBx:U23>-0.16424</PDBx:U23>
         <PDBx:U33>0.66164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="83">
         <PDBx:U11>0.43640</PDBx:U11>
         <PDBx:U12>0.28060</PDBx:U12>
         <PDBx:U13>-0.02610</PDBx:U13>
         <PDBx:U22>0.59392</PDBx:U22>
         <PDBx:U23>-0.12749</PDBx:U23>
         <PDBx:U33>0.59178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>157</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="84">
         <PDBx:U11>0.41320</PDBx:U11>
         <PDBx:U12>0.27184</PDBx:U12>
         <PDBx:U13>-0.02725</PDBx:U13>
         <PDBx:U22>0.59067</PDBx:U22>
         <PDBx:U23>-0.11833</PDBx:U23>
         <PDBx:U33>0.59007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>157</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
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      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="101">
         <PDBx:U11>0.46794</PDBx:U11>
         <PDBx:U12>0.30227</PDBx:U12>
         <PDBx:U13>0.05994</PDBx:U13>
         <PDBx:U22>0.76878</PDBx:U22>
         <PDBx:U23>-0.14367</PDBx:U23>
         <PDBx:U33>0.76015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>159</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="102">
         <PDBx:U11>0.43674</PDBx:U11>
         <PDBx:U12>0.27760</PDBx:U12>
         <PDBx:U13>0.03950</PDBx:U13>
         <PDBx:U22>0.67229</PDBx:U22>
         <PDBx:U23>-0.13718</PDBx:U23>
         <PDBx:U33>0.62699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="103">
         <PDBx:U11>0.42646</PDBx:U11>
         <PDBx:U12>0.26691</PDBx:U12>
         <PDBx:U13>0.04692</PDBx:U13>
         <PDBx:U22>0.65855</PDBx:U22>
         <PDBx:U23>-0.13516</PDBx:U23>
         <PDBx:U33>0.58969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="104">
         <PDBx:U11>0.42275</PDBx:U11>
         <PDBx:U12>0.26304</PDBx:U12>
         <PDBx:U13>0.03308</PDBx:U13>
         <PDBx:U22>0.62450</PDBx:U22>
         <PDBx:U23>-0.13420</PDBx:U23>
         <PDBx:U33>0.54914</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="105">
         <PDBx:U11>0.43198</PDBx:U11>
         <PDBx:U12>0.26213</PDBx:U12>
         <PDBx:U13>0.03834</PDBx:U13>
         <PDBx:U22>0.62418</PDBx:U22>
         <PDBx:U23>-0.13846</PDBx:U23>
         <PDBx:U33>0.53208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="106">
         <PDBx:U11>0.41615</PDBx:U11>
         <PDBx:U12>0.25337</PDBx:U12>
         <PDBx:U13>0.05151</PDBx:U13>
         <PDBx:U22>0.66785</PDBx:U22>
         <PDBx:U23>-0.12446</PDBx:U23>
         <PDBx:U33>0.59254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="107">
         <PDBx:U11>0.47025</PDBx:U11>
         <PDBx:U12>0.24291</PDBx:U12>
         <PDBx:U13>0.05976</PDBx:U13>
         <PDBx:U22>0.72157</PDBx:U22>
         <PDBx:U23>-0.12117</PDBx:U23>
         <PDBx:U33>0.62267</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="108">
         <PDBx:U11>0.38217</PDBx:U11>
         <PDBx:U12>0.23079</PDBx:U12>
         <PDBx:U13>0.06525</PDBx:U13>
         <PDBx:U22>0.65263</PDBx:U22>
         <PDBx:U23>-0.11118</PDBx:U23>
         <PDBx:U33>0.55072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="109">
         <PDBx:U11>0.35774</PDBx:U11>
         <PDBx:U12>0.22078</PDBx:U12>
         <PDBx:U13>0.07012</PDBx:U13>
         <PDBx:U22>0.62441</PDBx:U22>
         <PDBx:U23>-0.10645</PDBx:U23>
         <PDBx:U33>0.50044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="110">
         <PDBx:U11>0.44871</PDBx:U11>
         <PDBx:U12>0.21010</PDBx:U12>
         <PDBx:U13>0.07887</PDBx:U13>
         <PDBx:U22>0.73080</PDBx:U22>
         <PDBx:U23>-0.09868</PDBx:U23>
         <PDBx:U33>0.59887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="111">
         <PDBx:U11>0.47351</PDBx:U11>
         <PDBx:U12>0.20750</PDBx:U12>
         <PDBx:U13>0.08398</PDBx:U13>
         <PDBx:U22>0.77601</PDBx:U22>
         <PDBx:U23>-0.09539</PDBx:U23>
         <PDBx:U33>0.65699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="112">
         <PDBx:U11>0.46262</PDBx:U11>
         <PDBx:U12>0.20232</PDBx:U12>
         <PDBx:U13>0.08210</PDBx:U13>
         <PDBx:U22>0.73983</PDBx:U22>
         <PDBx:U23>-0.09395</PDBx:U23>
         <PDBx:U33>0.58754</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="113">
         <PDBx:U11>0.41127</PDBx:U11>
         <PDBx:U12>0.26046</PDBx:U12>
         <PDBx:U13>0.01575</PDBx:U13>
         <PDBx:U22>0.59790</PDBx:U22>
         <PDBx:U23>-0.12863</PDBx:U23>
         <PDBx:U33>0.53510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="114">
         <PDBx:U11>0.40420</PDBx:U11>
         <PDBx:U12>0.25435</PDBx:U12>
         <PDBx:U13>0.00312</PDBx:U13>
         <PDBx:U22>0.56424</PDBx:U22>
         <PDBx:U23>-0.12576</PDBx:U23>
         <PDBx:U33>0.49603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="115">
         <PDBx:U11>0.42713</PDBx:U11>
         <PDBx:U12>0.26442</PDBx:U12>
         <PDBx:U13>-0.00949</PDBx:U13>
         <PDBx:U22>0.56084</PDBx:U22>
         <PDBx:U23>-0.13221</PDBx:U23>
         <PDBx:U33>0.50740</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="116">
         <PDBx:U11>0.43108</PDBx:U11>
         <PDBx:U12>0.26904</PDBx:U12>
         <PDBx:U13>-0.01971</PDBx:U13>
         <PDBx:U22>0.56056</PDBx:U22>
         <PDBx:U23>-0.13083</PDBx:U23>
         <PDBx:U33>0.52558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="117">
         <PDBx:U11>0.37604</PDBx:U11>
         <PDBx:U12>0.24213</PDBx:U12>
         <PDBx:U13>-0.00579</PDBx:U13>
         <PDBx:U22>0.53584</PDBx:U22>
         <PDBx:U23>-0.11445</PDBx:U23>
         <PDBx:U33>0.46992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="118">
         <PDBx:U11>0.35463</PDBx:U11>
         <PDBx:U12>0.23179</PDBx:U12>
         <PDBx:U13>0.00567</PDBx:U13>
         <PDBx:U22>0.53787</PDBx:U22>
         <PDBx:U23>-0.10738</PDBx:U23>
         <PDBx:U33>0.46030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="119">
         <PDBx:U11>0.34670</PDBx:U11>
         <PDBx:U12>0.22445</PDBx:U12>
         <PDBx:U13>0.01293</PDBx:U13>
         <PDBx:U22>0.53052</PDBx:U22>
         <PDBx:U23>-0.10502</PDBx:U23>
         <PDBx:U33>0.43239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="120">
         <PDBx:U11>0.34471</PDBx:U11>
         <PDBx:U12>0.22964</PDBx:U12>
         <PDBx:U13>0.00883</PDBx:U13>
         <PDBx:U22>0.54926</PDBx:U22>
         <PDBx:U23>-0.10286</PDBx:U23>
         <PDBx:U33>0.48162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="121">
         <PDBx:U11>0.33027</PDBx:U11>
         <PDBx:U12>0.21527</PDBx:U12>
         <PDBx:U13>0.02326</PDBx:U13>
         <PDBx:U22>0.53353</PDBx:U22>
         <PDBx:U23>-0.09820</PDBx:U23>
         <PDBx:U33>0.42549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="122">
         <PDBx:U11>0.32725</PDBx:U11>
         <PDBx:U12>0.21962</PDBx:U12>
         <PDBx:U13>0.01941</PDBx:U13>
         <PDBx:U22>0.55143</PDBx:U22>
         <PDBx:U23>-0.09630</PDBx:U23>
         <PDBx:U33>0.47470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="123">
         <PDBx:U11>0.32086</PDBx:U11>
         <PDBx:U12>0.21252</PDBx:U12>
         <PDBx:U13>0.02676</PDBx:U13>
         <PDBx:U22>0.54339</PDBx:U22>
         <PDBx:U23>-0.09398</PDBx:U23>
         <PDBx:U33>0.44670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="124">
         <PDBx:U11>0.37098</PDBx:U11>
         <PDBx:U12>0.20285</PDBx:U12>
         <PDBx:U13>0.03709</PDBx:U13>
         <PDBx:U22>0.61101</PDBx:U22>
         <PDBx:U23>-0.08719</PDBx:U23>
         <PDBx:U33>0.50588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="125">
         <PDBx:U11>0.44380</PDBx:U11>
         <PDBx:U12>0.26738</PDBx:U12>
         <PDBx:U13>-0.00956</PDBx:U13>
         <PDBx:U22>0.55862</PDBx:U22>
         <PDBx:U23>-0.13877</PDBx:U23>
         <PDBx:U33>0.49728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="126">
         <PDBx:U11>0.46912</PDBx:U11>
         <PDBx:U12>0.27635</PDBx:U12>
         <PDBx:U13>-0.02092</PDBx:U13>
         <PDBx:U22>0.55556</PDBx:U22>
         <PDBx:U23>-0.14524</PDBx:U23>
         <PDBx:U33>0.50858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="127">
         <PDBx:U11>0.45899</PDBx:U11>
         <PDBx:U12>0.26763</PDBx:U12>
         <PDBx:U13>-0.03577</PDBx:U13>
         <PDBx:U22>0.52028</PDBx:U22>
         <PDBx:U23>-0.13936</PDBx:U23>
         <PDBx:U33>0.47331</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="128">
         <PDBx:U11>0.44989</PDBx:U11>
         <PDBx:U12>0.25966</PDBx:U12>
         <PDBx:U13>-0.03441</PDBx:U13>
         <PDBx:U22>0.50572</PDBx:U22>
         <PDBx:U23>-0.13748</PDBx:U23>
         <PDBx:U33>0.44271</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="129">
         <PDBx:U11>0.49793</PDBx:U11>
         <PDBx:U12>0.28455</PDBx:U12>
         <PDBx:U13>-0.01229</PDBx:U13>
         <PDBx:U22>0.57551</PDBx:U22>
         <PDBx:U23>-0.15680</PDBx:U23>
         <PDBx:U33>0.52221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="130">
         <PDBx:U11>0.52698</PDBx:U11>
         <PDBx:U12>0.29336</PDBx:U12>
         <PDBx:U13>-0.02383</PDBx:U13>
         <PDBx:U22>0.57242</PDBx:U22>
         <PDBx:U23>-0.16357</PDBx:U23>
         <PDBx:U33>0.53575</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="131">
         <PDBx:U11>0.55720</PDBx:U11>
         <PDBx:U12>0.30003</PDBx:U12>
         <PDBx:U13>-0.01499</PDBx:U13>
         <PDBx:U22>0.59134</PDBx:U22>
         <PDBx:U23>-0.17550</PDBx:U23>
         <PDBx:U33>0.54834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="132">
         <PDBx:U11>0.55651</PDBx:U11>
         <PDBx:U12>0.29859</PDBx:U12>
         <PDBx:U13>0.00079</PDBx:U13>
         <PDBx:U22>0.60997</PDBx:U22>
         <PDBx:U23>-0.17875</PDBx:U23>
         <PDBx:U33>0.54922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="133">
         <PDBx:U11>0.58357</PDBx:U11>
         <PDBx:U12>0.30596</PDBx:U12>
         <PDBx:U13>-0.02358</PDBx:U13>
         <PDBx:U22>0.58835</PDBx:U22>
         <PDBx:U23>-0.18154</PDBx:U23>
         <PDBx:U33>0.55812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="134">
         <PDBx:U11>0.46301</PDBx:U11>
         <PDBx:U12>0.26939</PDBx:U12>
         <PDBx:U13>-0.04970</PDBx:U13>
         <PDBx:U22>0.50886</PDBx:U22>
         <PDBx:U23>-0.13651</PDBx:U23>
         <PDBx:U33>0.47992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="135">
         <PDBx:U11>0.45651</PDBx:U11>
         <PDBx:U12>0.26089</PDBx:U12>
         <PDBx:U13>-0.06304</PDBx:U13>
         <PDBx:U22>0.47733</PDBx:U22>
         <PDBx:U23>-0.13104</PDBx:U23>
         <PDBx:U33>0.45008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="136">
         <PDBx:U11>0.47950</PDBx:U11>
         <PDBx:U12>0.26380</PDBx:U12>
         <PDBx:U13>-0.06680</PDBx:U13>
         <PDBx:U22>0.47301</PDBx:U22>
         <PDBx:U23>-0.13759</PDBx:U23>
         <PDBx:U33>0.44488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="137">
         <PDBx:U11>0.50974</PDBx:U11>
         <PDBx:U12>0.27519</PDBx:U12>
         <PDBx:U13>-0.06821</PDBx:U13>
         <PDBx:U22>0.48973</PDBx:U22>
         <PDBx:U23>-0.14591</PDBx:U23>
         <PDBx:U33>0.47358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="138">
         <PDBx:U11>0.46154</PDBx:U11>
         <PDBx:U12>0.26261</PDBx:U12>
         <PDBx:U13>-0.07665</PDBx:U13>
         <PDBx:U22>0.47041</PDBx:U22>
         <PDBx:U23>-0.12708</PDBx:U23>
         <PDBx:U33>0.46254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="139">
         <PDBx:U11>0.43911</PDBx:U11>
         <PDBx:U12>0.25843</PDBx:U12>
         <PDBx:U13>-0.07363</PDBx:U13>
         <PDBx:U22>0.47461</PDBx:U22>
         <PDBx:U23>-0.12031</PDBx:U23>
         <PDBx:U33>0.46763</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="140">
         <PDBx:U11>0.47609</PDBx:U11>
         <PDBx:U12>0.25360</PDBx:U12>
         <PDBx:U13>-0.08910</PDBx:U13>
         <PDBx:U22>0.45652</PDBx:U22>
         <PDBx:U23>-0.12216</PDBx:U23>
         <PDBx:U33>0.45050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="141">
         <PDBx:U11>0.44263</PDBx:U11>
         <PDBx:U12>0.25813</PDBx:U12>
         <PDBx:U13>-0.08785</PDBx:U13>
         <PDBx:U22>0.46702</PDBx:U22>
         <PDBx:U23>-0.11526</PDBx:U23>
         <PDBx:U33>0.47636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="142">
         <PDBx:U11>0.46711</PDBx:U11>
         <PDBx:U12>0.25361</PDBx:U12>
         <PDBx:U13>-0.06864</PDBx:U13>
         <PDBx:U22>0.45149</PDBx:U22>
         <PDBx:U23>-0.13387</PDBx:U23>
         <PDBx:U33>0.41087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="143">
         <PDBx:U11>0.60284</PDBx:U11>
         <PDBx:U12>0.25429</PDBx:U12>
         <PDBx:U13>-0.07425</PDBx:U13>
         <PDBx:U22>0.55870</PDBx:U22>
         <PDBx:U23>-0.13882</PDBx:U23>
         <PDBx:U33>0.51947</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="144">
         <PDBx:U11>0.57280</PDBx:U11>
         <PDBx:U12>0.24604</PDBx:U12>
         <PDBx:U13>-0.08797</PDBx:U13>
         <PDBx:U22>0.50231</PDBx:U22>
         <PDBx:U23>-0.13260</PDBx:U23>
         <PDBx:U33>0.47142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="145">
         <PDBx:U11>0.64336</PDBx:U11>
         <PDBx:U12>0.24716</PDBx:U12>
         <PDBx:U13>-0.09499</PDBx:U13>
         <PDBx:U22>0.54397</PDBx:U22>
         <PDBx:U23>-0.13635</PDBx:U23>
         <PDBx:U33>0.52142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="146">
         <PDBx:U11>0.53294</PDBx:U11>
         <PDBx:U12>0.25069</PDBx:U12>
         <PDBx:U13>-0.06442</PDBx:U13>
         <PDBx:U22>0.49710</PDBx:U22>
         <PDBx:U23>-0.14174</PDBx:U23>
         <PDBx:U33>0.43695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="147">
         <PDBx:U11>0.56109</PDBx:U11>
         <PDBx:U12>0.25926</PDBx:U12>
         <PDBx:U13>-0.05000</PDBx:U13>
         <PDBx:U22>0.54622</PDBx:U22>
         <PDBx:U23>-0.14945</PDBx:U23>
         <PDBx:U33>0.47832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="148">
         <PDBx:U11>0.47825</PDBx:U11>
         <PDBx:U12>0.23839</PDBx:U12>
         <PDBx:U13>-0.06238</PDBx:U13>
         <PDBx:U22>0.45755</PDBx:U22>
         <PDBx:U23>-0.13206</PDBx:U23>
         <PDBx:U33>0.38154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="149">
         <PDBx:U11>0.53324</PDBx:U11>
         <PDBx:U12>0.23729</PDBx:U12>
         <PDBx:U13>-0.09126</PDBx:U13>
         <PDBx:U22>0.47006</PDBx:U22>
         <PDBx:U23>-0.12356</PDBx:U23>
         <PDBx:U33>0.43831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="150">
         <PDBx:U11>0.55911</PDBx:U11>
         <PDBx:U12>0.22831</PDBx:U12>
         <PDBx:U13>-0.10200</PDBx:U13>
         <PDBx:U22>0.47135</PDBx:U22>
         <PDBx:U23>-0.11786</PDBx:U23>
         <PDBx:U33>0.44559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="151">
         <PDBx:U11>0.51140</PDBx:U11>
         <PDBx:U12>0.22098</PDBx:U12>
         <PDBx:U13>-0.10406</PDBx:U13>
         <PDBx:U22>0.43362</PDBx:U22>
         <PDBx:U23>-0.10962</PDBx:U23>
         <PDBx:U33>0.40972</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="152">
         <PDBx:U11>0.51257</PDBx:U11>
         <PDBx:U12>0.21966</PDBx:U12>
         <PDBx:U13>-0.09561</PDBx:U13>
         <PDBx:U22>0.46302</PDBx:U22>
         <PDBx:U23>-0.10708</PDBx:U23>
         <PDBx:U33>0.43126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="153">
         <PDBx:U11>0.64680</PDBx:U11>
         <PDBx:U12>0.22012</PDBx:U12>
         <PDBx:U13>-0.09949</PDBx:U13>
         <PDBx:U22>0.55517</PDBx:U22>
         <PDBx:U23>-0.11638</PDBx:U23>
         <PDBx:U33>0.51615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="154">
         <PDBx:U11>0.81582</PDBx:U11>
         <PDBx:U12>0.21200</PDBx:U12>
         <PDBx:U13>-0.11006</PDBx:U13>
         <PDBx:U22>0.69367</PDBx:U22>
         <PDBx:U23>-0.11221</PDBx:U23>
         <PDBx:U33>0.66417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="155">
         <PDBx:U11>0.94022</PDBx:U11>
         <PDBx:U12>0.21352</PDBx:U12>
         <PDBx:U13>-0.11972</PDBx:U13>
         <PDBx:U22>0.79494</PDBx:U22>
         <PDBx:U23>-0.11162</PDBx:U23>
         <PDBx:U33>0.78198</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="156">
         <PDBx:U11>0.81537</PDBx:U11>
         <PDBx:U12>0.20393</PDBx:U12>
         <PDBx:U13>-0.10842</PDBx:U13>
         <PDBx:U22>0.69221</PDBx:U22>
         <PDBx:U23>-0.10920</PDBx:U23>
         <PDBx:U33>0.65414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="157">
         <PDBx:U11>0.45398</PDBx:U11>
         <PDBx:U12>0.21552</PDBx:U12>
         <PDBx:U13>-0.11481</PDBx:U13>
         <PDBx:U22>0.35139</PDBx:U22>
         <PDBx:U23>-0.10545</PDBx:U23>
         <PDBx:U33>0.33846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="158">
         <PDBx:U11>0.47107</PDBx:U11>
         <PDBx:U12>0.20616</PDBx:U12>
         <PDBx:U13>-0.11655</PDBx:U13>
         <PDBx:U22>0.37262</PDBx:U22>
         <PDBx:U23>-0.09778</PDBx:U23>
         <PDBx:U33>0.36049</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="159">
         <PDBx:U11>0.49654</PDBx:U11>
         <PDBx:U12>0.19433</PDBx:U12>
         <PDBx:U13>-0.11393</PDBx:U13>
         <PDBx:U22>0.39467</PDBx:U22>
         <PDBx:U23>-0.09288</PDBx:U23>
         <PDBx:U33>0.37277</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="160">
         <PDBx:U11>0.52032</PDBx:U11>
         <PDBx:U12>0.19168</PDBx:U12>
         <PDBx:U13>-0.11882</PDBx:U13>
         <PDBx:U22>0.39552</PDBx:U22>
         <PDBx:U23>-0.09343</PDBx:U23>
         <PDBx:U33>0.37593</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="161">
         <PDBx:U11>0.54088</PDBx:U11>
         <PDBx:U12>0.20698</PDBx:U12>
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         <PDBx:U22>0.41666</PDBx:U22>
         <PDBx:U23>-0.09604</PDBx:U23>
         <PDBx:U33>0.42184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="162">
         <PDBx:U11>0.54974</PDBx:U11>
         <PDBx:U12>0.20678</PDBx:U12>
         <PDBx:U13>-0.12919</PDBx:U13>
         <PDBx:U22>0.42572</PDBx:U22>
         <PDBx:U23>-0.09592</PDBx:U23>
         <PDBx:U33>0.43078</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="163">
         <PDBx:U11>0.56307</PDBx:U11>
         <PDBx:U12>0.20375</PDBx:U12>
         <PDBx:U13>-0.13715</PDBx:U13>
         <PDBx:U22>0.40546</PDBx:U22>
         <PDBx:U23>-0.09607</PDBx:U23>
         <PDBx:U33>0.41692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="164">
         <PDBx:U11>0.57334</PDBx:U11>
         <PDBx:U12>0.21867</PDBx:U12>
         <PDBx:U13>-0.13192</PDBx:U13>
         <PDBx:U22>0.45529</PDBx:U22>
         <PDBx:U23>-0.09986</PDBx:U23>
         <PDBx:U33>0.47056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="165">
         <PDBx:U11>0.57584</PDBx:U11>
         <PDBx:U12>0.22033</PDBx:U12>
         <PDBx:U13>-0.13284</PDBx:U13>
         <PDBx:U22>0.45420</PDBx:U22>
         <PDBx:U23>-0.10096</PDBx:U23>
         <PDBx:U33>0.47104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="166">
         <PDBx:U11>0.50377</PDBx:U11>
         <PDBx:U12>0.19638</PDBx:U12>
         <PDBx:U13>-0.13016</PDBx:U13>
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         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>166</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>173</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
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      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="215">
         <PDBx:U11>0.39643</PDBx:U11>
         <PDBx:U12>0.18095</PDBx:U12>
         <PDBx:U13>-0.10056</PDBx:U13>
         <PDBx:U22>0.40521</PDBx:U22>
         <PDBx:U23>-0.06918</PDBx:U23>
         <PDBx:U33>0.39485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="216">
         <PDBx:U11>0.43124</PDBx:U11>
         <PDBx:U12>0.19157</PDBx:U12>
         <PDBx:U13>-0.12966</PDBx:U13>
         <PDBx:U22>0.37251</PDBx:U22>
         <PDBx:U23>-0.07490</PDBx:U23>
         <PDBx:U33>0.38718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="217">
         <PDBx:U11>0.67562</PDBx:U11>
         <PDBx:U12>0.19617</PDBx:U12>
         <PDBx:U13>-0.12684</PDBx:U13>
         <PDBx:U22>0.60736</PDBx:U22>
         <PDBx:U23>-0.08030</PDBx:U23>
         <PDBx:U33>0.61803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="218">
         <PDBx:U11>0.75132</PDBx:U11>
         <PDBx:U12>0.20945</PDBx:U12>
         <PDBx:U13>-0.13505</PDBx:U13>
         <PDBx:U22>0.67178</PDBx:U22>
         <PDBx:U23>-0.08587</PDBx:U23>
         <PDBx:U33>0.69446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="219">
         <PDBx:U11>0.83135</PDBx:U11>
         <PDBx:U12>0.20946</PDBx:U12>
         <PDBx:U13>-0.14987</PDBx:U13>
         <PDBx:U22>0.71934</PDBx:U22>
         <PDBx:U23>-0.08401</PDBx:U23>
         <PDBx:U33>0.75583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="220">
         <PDBx:U11>0.89269</PDBx:U11>
         <PDBx:U12>0.22147</PDBx:U12>
         <PDBx:U13>-0.15744</PDBx:U13>
         <PDBx:U22>0.76203</PDBx:U22>
         <PDBx:U23>-0.08950</PDBx:U23>
         <PDBx:U33>0.81007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="221">
         <PDBx:U11>0.35773</PDBx:U11>
         <PDBx:U12>0.17643</PDBx:U12>
         <PDBx:U13>-0.10136</PDBx:U13>
         <PDBx:U22>0.33337</PDBx:U22>
         <PDBx:U23>-0.07155</PDBx:U23>
         <PDBx:U33>0.31599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="222">
         <PDBx:U11>0.31521</PDBx:U11>
         <PDBx:U12>0.17705</PDBx:U12>
         <PDBx:U13>-0.08954</PDBx:U13>
         <PDBx:U22>0.31194</PDBx:U22>
         <PDBx:U23>-0.07275</PDBx:U23>
         <PDBx:U33>0.28125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="223">
         <PDBx:U11>0.45458</PDBx:U11>
         <PDBx:U12>0.18606</PDBx:U12>
         <PDBx:U13>-0.09122</PDBx:U13>
         <PDBx:U22>0.44137</PDBx:U22>
         <PDBx:U23>-0.07992</PDBx:U23>
         <PDBx:U33>0.40880</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="224">
         <PDBx:U11>0.34939</PDBx:U11>
         <PDBx:U12>0.18562</PDBx:U12>
         <PDBx:U13>-0.09820</PDBx:U13>
         <PDBx:U22>0.31072</PDBx:U22>
         <PDBx:U23>-0.08170</PDBx:U23>
         <PDBx:U33>0.28134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="225">
         <PDBx:U11>0.31865</PDBx:U11>
         <PDBx:U12>0.16630</PDBx:U12>
         <PDBx:U13>-0.08220</PDBx:U13>
         <PDBx:U22>0.31854</PDBx:U22>
         <PDBx:U23>-0.06765</PDBx:U23>
         <PDBx:U33>0.27746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="226">
         <PDBx:U11>0.31490</PDBx:U11>
         <PDBx:U12>0.16780</PDBx:U12>
         <PDBx:U13>-0.07116</PDBx:U13>
         <PDBx:U22>0.33608</PDBx:U22>
         <PDBx:U23>-0.06850</PDBx:U23>
         <PDBx:U33>0.28072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="227">
         <PDBx:U11>0.31638</PDBx:U11>
         <PDBx:U12>0.15780</PDBx:U12>
         <PDBx:U13>-0.08102</PDBx:U13>
         <PDBx:U22>0.32312</PDBx:U22>
         <PDBx:U23>-0.06093</PDBx:U23>
         <PDBx:U33>0.28589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="228">
         <PDBx:U11>0.42081</PDBx:U11>
         <PDBx:U12>0.19411</PDBx:U12>
         <PDBx:U13>-0.08451</PDBx:U13>
         <PDBx:U22>0.42683</PDBx:U22>
         <PDBx:U23>-0.08412</PDBx:U23>
         <PDBx:U33>0.38975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="229">
         <PDBx:U11>0.35827</PDBx:U11>
         <PDBx:U12>0.20364</PDBx:U12>
         <PDBx:U13>-0.08489</PDBx:U13>
         <PDBx:U22>0.35623</PDBx:U22>
         <PDBx:U23>-0.09178</PDBx:U23>
         <PDBx:U33>0.31743</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="230">
         <PDBx:U11>0.38718</PDBx:U11>
         <PDBx:U12>0.20299</PDBx:U12>
         <PDBx:U13>-0.07285</PDBx:U13>
         <PDBx:U22>0.40386</PDBx:U22>
         <PDBx:U23>-0.09294</PDBx:U23>
         <PDBx:U33>0.34746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="231">
         <PDBx:U11>0.32665</PDBx:U11>
         <PDBx:U12>0.19773</PDBx:U12>
         <PDBx:U13>-0.06362</PDBx:U13>
         <PDBx:U22>0.36624</PDBx:U22>
         <PDBx:U23>-0.08832</PDBx:U23>
         <PDBx:U33>0.30123</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="232">
         <PDBx:U11>0.37973</PDBx:U11>
         <PDBx:U12>0.21627</PDBx:U12>
         <PDBx:U13>-0.08792</PDBx:U13>
         <PDBx:U22>0.38014</PDBx:U22>
         <PDBx:U23>-0.09743</PDBx:U23>
         <PDBx:U33>0.35360</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="233">
         <PDBx:U11>0.39655</PDBx:U11>
         <PDBx:U12>0.21800</PDBx:U12>
         <PDBx:U13>-0.10182</PDBx:U13>
         <PDBx:U22>0.37420</PDBx:U22>
         <PDBx:U23>-0.09632</PDBx:U23>
         <PDBx:U33>0.36463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="234">
         <PDBx:U11>0.36680</PDBx:U11>
         <PDBx:U12>0.21812</PDBx:U12>
         <PDBx:U13>-0.07860</PDBx:U13>
         <PDBx:U22>0.39914</PDBx:U22>
         <PDBx:U23>-0.09606</PDBx:U23>
         <PDBx:U33>0.37072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="235">
         <PDBx:U11>0.36400</PDBx:U11>
         <PDBx:U12>0.20829</PDBx:U12>
         <PDBx:U13>-0.07354</PDBx:U13>
         <PDBx:U22>0.36885</PDBx:U22>
         <PDBx:U23>-0.09898</PDBx:U23>
         <PDBx:U33>0.30765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="236">
         <PDBx:U11>0.41166</PDBx:U11>
         <PDBx:U12>0.20984</PDBx:U12>
         <PDBx:U13>-0.06333</PDBx:U13>
         <PDBx:U22>0.43108</PDBx:U22>
         <PDBx:U23>-0.10170</PDBx:U23>
         <PDBx:U33>0.35271</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="237">
         <PDBx:U11>0.38019</PDBx:U11>
         <PDBx:U12>0.22145</PDBx:U12>
         <PDBx:U13>-0.05714</PDBx:U13>
         <PDBx:U22>0.41012</PDBx:U22>
         <PDBx:U23>-0.10963</PDBx:U23>
         <PDBx:U33>0.33337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="238">
         <PDBx:U11>0.40439</PDBx:U11>
         <PDBx:U12>0.23018</PDBx:U12>
         <PDBx:U13>-0.06344</PDBx:U13>
         <PDBx:U22>0.41806</PDBx:U22>
         <PDBx:U23>-0.11587</PDBx:U23>
         <PDBx:U33>0.35458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="239">
         <PDBx:U11>0.43221</PDBx:U11>
         <PDBx:U12>0.20863</PDBx:U12>
         <PDBx:U13>-0.06770</PDBx:U13>
         <PDBx:U22>0.43191</PDBx:U22>
         <PDBx:U23>-0.10418</PDBx:U23>
         <PDBx:U33>0.34759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="240">
         <PDBx:U11>0.37416</PDBx:U11>
         <PDBx:U12>0.21090</PDBx:U12>
         <PDBx:U13>-0.05812</PDBx:U13>
         <PDBx:U22>0.38713</PDBx:U22>
         <PDBx:U23>-0.10767</PDBx:U23>
         <PDBx:U33>0.28434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="241">
         <PDBx:U11>0.56737</PDBx:U11>
         <PDBx:U12>0.20878</PDBx:U12>
         <PDBx:U13>-0.06316</PDBx:U13>
         <PDBx:U22>0.56117</PDBx:U22>
         <PDBx:U23>-0.10981</PDBx:U23>
         <PDBx:U33>0.45368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="242">
         <PDBx:U11>0.67538</PDBx:U11>
         <PDBx:U12>0.20456</PDBx:U12>
         <PDBx:U13>-0.07334</PDBx:U13>
         <PDBx:U22>0.64651</PDBx:U22>
         <PDBx:U23>-0.10764</PDBx:U23>
         <PDBx:U33>0.55054</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="243">
         <PDBx:U11>0.57310</PDBx:U11>
         <PDBx:U12>0.21064</PDBx:U12>
         <PDBx:U13>-0.05656</PDBx:U13>
         <PDBx:U22>0.57397</PDBx:U22>
         <PDBx:U23>-0.11369</PDBx:U23>
         <PDBx:U33>0.45168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="244">
         <PDBx:U11>0.37094</PDBx:U11>
         <PDBx:U12>0.22149</PDBx:U12>
         <PDBx:U13>-0.04425</PDBx:U13>
         <PDBx:U22>0.42707</PDBx:U22>
         <PDBx:U23>-0.10931</PDBx:U23>
         <PDBx:U33>0.33764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>178</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="245">
         <PDBx:U11>0.38781</PDBx:U11>
         <PDBx:U12>0.23180</PDBx:U12>
         <PDBx:U13>-0.03545</PDBx:U13>
         <PDBx:U22>0.45753</PDBx:U22>
         <PDBx:U23>-0.11672</PDBx:U23>
         <PDBx:U33>0.36942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>178</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="246">
         <PDBx:U11>0.39231</PDBx:U11>
         <PDBx:U12>0.23237</PDBx:U12>
         <PDBx:U13>-0.02278</PDBx:U13>
         <PDBx:U22>0.47447</PDBx:U22>
         <PDBx:U23>-0.12025</PDBx:U23>
         <PDBx:U33>0.36585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>178</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="247">
         <PDBx:U11>0.37515</PDBx:U11>
         <PDBx:U12>0.22391</PDBx:U12>
         <PDBx:U13>-0.01870</PDBx:U13>
         <PDBx:U22>0.46582</PDBx:U22>
         <PDBx:U23>-0.11419</PDBx:U23>
         <PDBx:U33>0.34128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>178</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="248">
         <PDBx:U11>0.37606</PDBx:U11>
         <PDBx:U12>0.23165</PDBx:U12>
         <PDBx:U13>-0.03026</PDBx:U13>
         <PDBx:U22>0.46889</PDBx:U22>
         <PDBx:U23>-0.11299</PDBx:U23>
         <PDBx:U33>0.38822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>178</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="249">
         <PDBx:U11>0.38874</PDBx:U11>
         <PDBx:U12>0.23248</PDBx:U12>
         <PDBx:U13>-0.04453</PDBx:U13>
         <PDBx:U22>0.47029</PDBx:U22>
         <PDBx:U23>-0.10949</PDBx:U23>
         <PDBx:U33>0.41305</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>178</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="250">
         <PDBx:U11>0.41773</PDBx:U11>
         <PDBx:U12>0.24266</PDBx:U12>
         <PDBx:U13>-0.01617</PDBx:U13>
         <PDBx:U22>0.50066</PDBx:U22>
         <PDBx:U23>-0.13012</PDBx:U23>
         <PDBx:U33>0.39283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="251">
         <PDBx:U11>0.42683</PDBx:U11>
         <PDBx:U12>0.24415</PDBx:U12>
         <PDBx:U13>-0.00104</PDBx:U13>
         <PDBx:U22>0.52532</PDBx:U22>
         <PDBx:U23>-0.13462</PDBx:U23>
         <PDBx:U33>0.39870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="252">
         <PDBx:U11>0.41725</PDBx:U11>
         <PDBx:U12>0.24403</PDBx:U12>
         <PDBx:U13>0.01149</PDBx:U13>
         <PDBx:U22>0.54511</PDBx:U22>
         <PDBx:U23>-0.13201</PDBx:U23>
         <PDBx:U33>0.41821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="253">
         <PDBx:U11>0.42526</PDBx:U11>
         <PDBx:U12>0.25148</PDBx:U12>
         <PDBx:U13>0.01208</PDBx:U13>
         <PDBx:U22>0.55905</PDBx:U22>
         <PDBx:U23>-0.13530</PDBx:U23>
         <PDBx:U33>0.44907</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="254">
         <PDBx:U11>0.46587</PDBx:U11>
         <PDBx:U12>0.25511</PDBx:U12>
         <PDBx:U13>0.00198</PDBx:U13>
         <PDBx:U22>0.55018</PDBx:U22>
         <PDBx:U23>-0.14769</PDBx:U23>
         <PDBx:U33>0.42615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="255">
         <PDBx:U11>0.47583</PDBx:U11>
         <PDBx:U12>0.25472</PDBx:U12>
         <PDBx:U13>-0.01086</PDBx:U13>
         <PDBx:U22>0.52845</PDBx:U22>
         <PDBx:U23>-0.15070</PDBx:U23>
         <PDBx:U33>0.40811</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="256">
         <PDBx:U11>0.47596</PDBx:U11>
         <PDBx:U12>0.25622</PDBx:U12>
         <PDBx:U13>0.02000</PDBx:U13>
         <PDBx:U22>0.57730</PDBx:U22>
         <PDBx:U23>-0.15316</PDBx:U23>
         <PDBx:U33>0.43259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="257">
         <PDBx:U11>0.51435</PDBx:U11>
         <PDBx:U12>0.26602</PDBx:U12>
         <PDBx:U13>-0.01040</PDBx:U13>
         <PDBx:U22>0.54741</PDBx:U22>
         <PDBx:U23>-0.16380</PDBx:U23>
         <PDBx:U33>0.43762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="258">
         <PDBx:U11>0.40291</PDBx:U11>
         <PDBx:U12>0.23600</PDBx:U12>
         <PDBx:U13>0.02172</PDBx:U13>
         <PDBx:U22>0.54905</PDBx:U22>
         <PDBx:U23>-0.12618</PDBx:U23>
         <PDBx:U33>0.40376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="259">
         <PDBx:U11>0.39694</PDBx:U11>
         <PDBx:U12>0.23475</PDBx:U12>
         <PDBx:U13>0.03540</PDBx:U13>
         <PDBx:U22>0.57056</PDBx:U22>
         <PDBx:U23>-0.12386</PDBx:U23>
         <PDBx:U33>0.42424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="260">
         <PDBx:U11>0.42452</PDBx:U11>
         <PDBx:U12>0.24184</PDBx:U12>
         <PDBx:U13>0.05137</PDBx:U13>
         <PDBx:U22>0.60684</PDBx:U22>
         <PDBx:U23>-0.13383</PDBx:U23>
         <PDBx:U33>0.44928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="261">
         <PDBx:U11>0.43141</PDBx:U11>
         <PDBx:U12>0.23800</PDBx:U12>
         <PDBx:U13>0.05980</PDBx:U13>
         <PDBx:U22>0.61591</PDBx:U22>
         <PDBx:U23>-0.13428</PDBx:U23>
         <PDBx:U33>0.43597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="262">
         <PDBx:U11>0.37107</PDBx:U11>
         <PDBx:U12>0.22222</PDBx:U12>
         <PDBx:U13>0.03914</PDBx:U13>
         <PDBx:U22>0.55839</PDBx:U22>
         <PDBx:U23>-0.11227</PDBx:U23>
         <PDBx:U33>0.39970</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="263">
         <PDBx:U11>0.40329</PDBx:U11>
         <PDBx:U12>0.21970</PDBx:U12>
         <PDBx:U13>0.05304</PDBx:U13>
         <PDBx:U22>0.61767</PDBx:U22>
         <PDBx:U23>-0.10946</PDBx:U23>
         <PDBx:U33>0.46028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="274">
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.17273</PDBx:U23>
         <PDBx:U33>0.54536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="276">
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>182</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.13573</PDBx:U23>
         <PDBx:U33>0.68695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>182</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>182</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>182</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="280">
         <PDBx:U11>0.56939</PDBx:U11>
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         <PDBx:pdbx_auth_seq_id>185</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="297">
         <PDBx:U11>0.44727</PDBx:U11>
         <PDBx:U12>0.23159</PDBx:U12>
         <PDBx:U13>0.02539</PDBx:U13>
         <PDBx:U22>0.55935</PDBx:U22>
         <PDBx:U23>-0.13719</PDBx:U23>
         <PDBx:U33>0.35437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>185</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="298">
         <PDBx:U11>0.44808</PDBx:U11>
         <PDBx:U12>0.22224</PDBx:U12>
         <PDBx:U13>0.04272</PDBx:U13>
         <PDBx:U22>0.60057</PDBx:U22>
         <PDBx:U23>-0.12392</PDBx:U23>
         <PDBx:U33>0.37800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="299">
         <PDBx:U11>0.41393</PDBx:U11>
         <PDBx:U12>0.21444</PDBx:U12>
         <PDBx:U13>0.03112</PDBx:U13>
         <PDBx:U22>0.56123</PDBx:U22>
         <PDBx:U23>-0.11323</PDBx:U23>
         <PDBx:U33>0.33935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="300">
         <PDBx:U11>0.40744</PDBx:U11>
         <PDBx:U12>0.21595</PDBx:U12>
         <PDBx:U13>0.01736</PDBx:U13>
         <PDBx:U22>0.54140</PDBx:U22>
         <PDBx:U23>-0.11236</PDBx:U23>
         <PDBx:U33>0.34493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="301">
         <PDBx:U11>0.38131</PDBx:U11>
         <PDBx:U12>0.22009</PDBx:U12>
         <PDBx:U13>0.01843</PDBx:U13>
         <PDBx:U22>0.52047</PDBx:U22>
         <PDBx:U23>-0.11461</PDBx:U23>
         <PDBx:U33>0.34057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="302">
         <PDBx:U11>0.57255</PDBx:U11>
         <PDBx:U12>0.20601</PDBx:U12>
         <PDBx:U13>0.03919</PDBx:U13>
         <PDBx:U22>0.74175</PDBx:U22>
         <PDBx:U23>-0.10160</PDBx:U23>
         <PDBx:U33>0.51043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="303">
         <PDBx:U11>0.64630</PDBx:U11>
         <PDBx:U12>0.19847</PDBx:U12>
         <PDBx:U13>0.02921</PDBx:U13>
         <PDBx:U22>0.81357</PDBx:U22>
         <PDBx:U23>-0.09044</PDBx:U23>
         <PDBx:U33>0.59177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="304">
         <PDBx:U11>0.72258</PDBx:U11>
         <PDBx:U12>0.19059</PDBx:U12>
         <PDBx:U13>0.03865</PDBx:U13>
         <PDBx:U22>0.91047</PDBx:U22>
         <PDBx:U23>-0.07998</PDBx:U23>
         <PDBx:U33>0.68327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="305">
         <PDBx:U11>0.65414</PDBx:U11>
         <PDBx:U12>0.18273</PDBx:U12>
         <PDBx:U13>0.03055</PDBx:U13>
         <PDBx:U22>0.83847</PDBx:U22>
         <PDBx:U23>-0.06941</PDBx:U23>
         <PDBx:U33>0.61821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="306">
         <PDBx:U11>0.65736</PDBx:U11>
         <PDBx:U12>0.17489</PDBx:U12>
         <PDBx:U13>0.03650</PDBx:U13>
         <PDBx:U22>0.85460</PDBx:U22>
         <PDBx:U23>-0.05908</PDBx:U23>
         <PDBx:U33>0.63103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="307">
         <PDBx:U11>0.73748</PDBx:U11>
         <PDBx:U12>0.17340</PDBx:U12>
         <PDBx:U13>0.05040</PDBx:U13>
         <PDBx:U22>0.95239</PDBx:U22>
         <PDBx:U23>-0.05743</PDBx:U23>
         <PDBx:U33>0.71787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="308">
         <PDBx:U11>0.46814</PDBx:U11>
         <PDBx:U12>0.16815</PDBx:U12>
         <PDBx:U13>0.02937</PDBx:U13>
         <PDBx:U22>0.65944</PDBx:U22>
         <PDBx:U23>-0.05059</PDBx:U23>
         <PDBx:U33>0.44425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="309">
         <PDBx:U11>0.37295</PDBx:U11>
         <PDBx:U12>0.21248</PDBx:U12>
         <PDBx:U13>0.00455</PDBx:U13>
         <PDBx:U22>0.48913</PDBx:U22>
         <PDBx:U23>-0.10926</PDBx:U23>
         <PDBx:U33>0.29577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="310">
         <PDBx:U11>0.37540</PDBx:U11>
         <PDBx:U12>0.21206</PDBx:U12>
         <PDBx:U13>-0.00830</PDBx:U13>
         <PDBx:U22>0.47650</PDBx:U22>
         <PDBx:U23>-0.10751</PDBx:U23>
         <PDBx:U33>0.30509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="311">
         <PDBx:U11>0.34980</PDBx:U11>
         <PDBx:U12>0.20302</PDBx:U12>
         <PDBx:U13>-0.00908</PDBx:U13>
         <PDBx:U22>0.46202</PDBx:U22>
         <PDBx:U23>-0.09612</PDBx:U23>
         <PDBx:U33>0.29459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="312">
         <PDBx:U11>0.38003</PDBx:U11>
         <PDBx:U12>0.19614</PDBx:U12>
         <PDBx:U13>-0.00616</PDBx:U13>
         <PDBx:U22>0.50048</PDBx:U22>
         <PDBx:U23>-0.08856</PDBx:U23>
         <PDBx:U33>0.31985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="313">
         <PDBx:U11>0.40800</PDBx:U11>
         <PDBx:U12>0.21149</PDBx:U12>
         <PDBx:U13>-0.02072</PDBx:U13>
         <PDBx:U22>0.48303</PDBx:U22>
         <PDBx:U23>-0.10978</PDBx:U23>
         <PDBx:U33>0.31523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="314">
         <PDBx:U11>0.43187</PDBx:U11>
         <PDBx:U12>0.21984</PDBx:U12>
         <PDBx:U13>-0.02282</PDBx:U13>
         <PDBx:U22>0.48857</PDBx:U22>
         <PDBx:U23>-0.12157</PDBx:U23>
         <PDBx:U33>0.32576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="315">
         <PDBx:U11>0.46143</PDBx:U11>
         <PDBx:U12>0.22143</PDBx:U12>
         <PDBx:U13>-0.03522</PDBx:U13>
         <PDBx:U22>0.49042</PDBx:U22>
         <PDBx:U23>-0.12519</PDBx:U23>
         <PDBx:U33>0.34373</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="316">
         <PDBx:U11>0.44800</PDBx:U11>
         <PDBx:U12>0.22650</PDBx:U12>
         <PDBx:U13>-0.01325</PDBx:U13>
         <PDBx:U22>0.50849</PDBx:U22>
         <PDBx:U23>-0.13079</PDBx:U23>
         <PDBx:U33>0.33762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="317">
         <PDBx:U11>0.47949</PDBx:U11>
         <PDBx:U12>0.22876</PDBx:U12>
         <PDBx:U13>-0.03370</PDBx:U13>
         <PDBx:U22>0.49537</PDBx:U22>
         <PDBx:U23>-0.13600</PDBx:U23>
         <PDBx:U33>0.35126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="318">
         <PDBx:U11>0.50726</PDBx:U11>
         <PDBx:U12>0.23217</PDBx:U12>
         <PDBx:U13>-0.02018</PDBx:U13>
         <PDBx:U22>0.54203</PDBx:U22>
         <PDBx:U23>-0.14007</PDBx:U23>
         <PDBx:U33>0.38314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="319">
         <PDBx:U11>0.32731</PDBx:U11>
         <PDBx:U12>0.20314</PDBx:U12>
         <PDBx:U13>-0.01321</PDBx:U13>
         <PDBx:U22>0.43855</PDBx:U22>
         <PDBx:U23>-0.09504</PDBx:U23>
         <PDBx:U33>0.29007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="320">
         <PDBx:U11>0.30290</PDBx:U11>
         <PDBx:U12>0.19416</PDBx:U12>
         <PDBx:U13>-0.01384</PDBx:U13>
         <PDBx:U22>0.42214</PDBx:U22>
         <PDBx:U23>-0.08552</PDBx:U23>
         <PDBx:U33>0.28092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="321">
         <PDBx:U11>0.32758</PDBx:U11>
         <PDBx:U12>0.19297</PDBx:U12>
         <PDBx:U13>-0.02680</PDBx:U13>
         <PDBx:U22>0.42668</PDBx:U22>
         <PDBx:U23>-0.08515</PDBx:U23>
         <PDBx:U33>0.30418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="322">
         <PDBx:U11>0.40436</PDBx:U11>
         <PDBx:U12>0.20020</PDBx:U12>
         <PDBx:U13>-0.03413</PDBx:U13>
         <PDBx:U22>0.48687</PDBx:U22>
         <PDBx:U23>-0.09205</PDBx:U23>
         <PDBx:U33>0.37340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="323">
         <PDBx:U11>0.29878</PDBx:U11>
         <PDBx:U12>0.19440</PDBx:U12>
         <PDBx:U13>-0.00367</PDBx:U13>
         <PDBx:U22>0.44117</PDBx:U22>
         <PDBx:U23>-0.08419</PDBx:U23>
         <PDBx:U33>0.30361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="324">
         <PDBx:U11>0.33048</PDBx:U11>
         <PDBx:U12>0.19433</PDBx:U12>
         <PDBx:U13>0.01045</PDBx:U13>
         <PDBx:U22>0.49160</PDBx:U22>
         <PDBx:U23>-0.08401</PDBx:U23>
         <PDBx:U33>0.33400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="325">
         <PDBx:U11>0.31654</PDBx:U11>
         <PDBx:U12>0.20438</PDBx:U12>
         <PDBx:U13>-0.00538</PDBx:U13>
         <PDBx:U22>0.45772</PDBx:U22>
         <PDBx:U23>-0.09231</PDBx:U23>
         <PDBx:U33>0.33468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="326">
         <PDBx:U11>0.28358</PDBx:U11>
         <PDBx:U12>0.18348</PDBx:U12>
         <PDBx:U13>-0.02937</PDBx:U13>
         <PDBx:U22>0.38218</PDBx:U22>
         <PDBx:U23>-0.07699</PDBx:U23>
         <PDBx:U33>0.26557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>189</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="327">
         <PDBx:U11>0.28077</PDBx:U11>
         <PDBx:U12>0.18139</PDBx:U12>
         <PDBx:U13>-0.03976</PDBx:U13>
         <PDBx:U22>0.36313</PDBx:U22>
         <PDBx:U23>-0.07595</PDBx:U23>
         <PDBx:U33>0.26416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>189</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="328">
         <PDBx:U11>0.30025</PDBx:U11>
         <PDBx:U12>0.18171</PDBx:U12>
         <PDBx:U13>-0.03784</PDBx:U13>
         <PDBx:U22>0.39680</PDBx:U22>
         <PDBx:U23>-0.07415</PDBx:U23>
         <PDBx:U33>0.30931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>189</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="329">
         <PDBx:U11>0.32436</PDBx:U11>
         <PDBx:U12>0.17756</PDBx:U12>
         <PDBx:U13>-0.02876</PDBx:U13>
         <PDBx:U22>0.44134</PDBx:U22>
         <PDBx:U23>-0.06972</PDBx:U23>
         <PDBx:U33>0.34940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>189</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="330">
         <PDBx:U11>0.27755</PDBx:U11>
         <PDBx:U12>0.17081</PDBx:U12>
         <PDBx:U13>-0.04319</PDBx:U13>
         <PDBx:U22>0.34922</PDBx:U22>
         <PDBx:U23>-0.06895</PDBx:U23>
         <PDBx:U33>0.25071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>189</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="331">
         <PDBx:U11>0.28896</PDBx:U11>
         <PDBx:U12>0.18713</PDBx:U12>
         <PDBx:U13>-0.04680</PDBx:U13>
         <PDBx:U22>0.37484</PDBx:U22>
         <PDBx:U23>-0.07752</PDBx:U23>
         <PDBx:U33>0.30251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="332">
         <PDBx:U11>0.28671</PDBx:U11>
         <PDBx:U12>0.18833</PDBx:U12>
         <PDBx:U13>-0.04738</PDBx:U13>
         <PDBx:U22>0.38577</PDBx:U22>
         <PDBx:U23>-0.07577</PDBx:U23>
         <PDBx:U33>0.32535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="333">
         <PDBx:U11>0.32358</PDBx:U11>
         <PDBx:U12>0.18441</PDBx:U12>
         <PDBx:U13>-0.05939</PDBx:U13>
         <PDBx:U22>0.40525</PDBx:U22>
         <PDBx:U23>-0.07254</PDBx:U23>
         <PDBx:U33>0.35771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="334">
         <PDBx:U11>0.30372</PDBx:U11>
         <PDBx:U12>0.18910</PDBx:U12>
         <PDBx:U13>-0.06948</PDBx:U13>
         <PDBx:U22>0.36357</PDBx:U22>
         <PDBx:U23>-0.07621</PDBx:U23>
         <PDBx:U33>0.32359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="335">
         <PDBx:U11>0.30635</PDBx:U11>
         <PDBx:U12>0.20100</PDBx:U12>
         <PDBx:U13>-0.04612</PDBx:U13>
         <PDBx:U22>0.41428</PDBx:U22>
         <PDBx:U23>-0.08307</PDBx:U23>
         <PDBx:U33>0.36013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="336">
         <PDBx:U11>0.33189</PDBx:U11>
         <PDBx:U12>0.20210</PDBx:U12>
         <PDBx:U13>-0.04714</PDBx:U13>
         <PDBx:U22>0.45639</PDBx:U22>
         <PDBx:U23>-0.08050</PDBx:U23>
         <PDBx:U33>0.41434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="337">
         <PDBx:U11>0.30958</PDBx:U11>
         <PDBx:U12>0.20468</PDBx:U12>
         <PDBx:U13>-0.03294</PDBx:U13>
         <PDBx:U22>0.43351</PDBx:U22>
         <PDBx:U23>-0.08699</PDBx:U23>
         <PDBx:U33>0.36532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="338">
         <PDBx:U11>0.26997</PDBx:U11>
         <PDBx:U12>0.17614</PDBx:U12>
         <PDBx:U13>-0.05837</PDBx:U13>
         <PDBx:U22>0.36056</PDBx:U22>
         <PDBx:U23>-0.06589</PDBx:U23>
         <PDBx:U33>0.31588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="339">
         <PDBx:U11>0.27105</PDBx:U11>
         <PDBx:U12>0.17226</PDBx:U12>
         <PDBx:U13>-0.06907</PDBx:U13>
         <PDBx:U22>0.34745</PDBx:U22>
         <PDBx:U23>-0.06278</PDBx:U23>
         <PDBx:U33>0.31370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="340">
         <PDBx:U11>0.28372</PDBx:U11>
         <PDBx:U12>0.17990</PDBx:U12>
         <PDBx:U13>-0.07583</PDBx:U13>
         <PDBx:U22>0.36819</PDBx:U22>
         <PDBx:U23>-0.06463</PDBx:U23>
         <PDBx:U33>0.34647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="341">
         <PDBx:U11>0.28565</PDBx:U11>
         <PDBx:U12>0.18032</PDBx:U12>
         <PDBx:U13>-0.07051</PDBx:U13>
         <PDBx:U22>0.39439</PDBx:U22>
         <PDBx:U23>-0.06292</PDBx:U23>
         <PDBx:U33>0.37375</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="342">
         <PDBx:U11>0.26400</PDBx:U11>
         <PDBx:U12>0.16065</PDBx:U12>
         <PDBx:U13>-0.06505</PDBx:U13>
         <PDBx:U22>0.34633</PDBx:U22>
         <PDBx:U23>-0.05540</PDBx:U23>
         <PDBx:U33>0.31006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="343">
         <PDBx:U11>0.33182</PDBx:U11>
         <PDBx:U12>0.15600</PDBx:U12>
         <PDBx:U13>-0.07531</PDBx:U13>
         <PDBx:U22>0.39957</PDBx:U22>
         <PDBx:U23>-0.05237</PDBx:U23>
         <PDBx:U33>0.37254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="344">
         <PDBx:U11>0.28308</PDBx:U11>
         <PDBx:U12>0.14494</PDBx:U12>
         <PDBx:U13>-0.06976</PDBx:U13>
         <PDBx:U22>0.35320</PDBx:U22>
         <PDBx:U23>-0.04608</PDBx:U23>
         <PDBx:U33>0.32211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="345">
         <PDBx:U11>0.27659</PDBx:U11>
         <PDBx:U12>0.14053</PDBx:U12>
         <PDBx:U13>-0.07953</PDBx:U13>
         <PDBx:U22>0.33408</PDBx:U22>
         <PDBx:U23>-0.04354</PDBx:U23>
         <PDBx:U33>0.31111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="346">
         <PDBx:U11>0.29524</PDBx:U11>
         <PDBx:U12>0.13097</PDBx:U12>
         <PDBx:U13>-0.07367</PDBx:U13>
         <PDBx:U22>0.35454</PDBx:U22>
         <PDBx:U23>-0.03823</PDBx:U23>
         <PDBx:U33>0.32818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="347">
         <PDBx:U11>0.31337</PDBx:U11>
         <PDBx:U12>0.18601</PDBx:U12>
         <PDBx:U13>-0.08787</PDBx:U13>
         <PDBx:U22>0.37772</PDBx:U22>
         <PDBx:U23>-0.06781</PDBx:U23>
         <PDBx:U33>0.36566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="348">
         <PDBx:U11>0.32025</PDBx:U11>
         <PDBx:U12>0.19469</PDBx:U12>
         <PDBx:U13>-0.09630</PDBx:U13>
         <PDBx:U22>0.39042</PDBx:U22>
         <PDBx:U23>-0.06947</PDBx:U23>
         <PDBx:U33>0.39066</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="349">
         <PDBx:U11>0.34341</PDBx:U11>
         <PDBx:U12>0.18905</PDBx:U12>
         <PDBx:U13>-0.10799</PDBx:U13>
         <PDBx:U22>0.40181</PDBx:U22>
         <PDBx:U23>-0.06478</PDBx:U23>
         <PDBx:U33>0.40926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="350">
         <PDBx:U11>0.37164</PDBx:U11>
         <PDBx:U12>0.18691</PDBx:U12>
         <PDBx:U13>-0.11676</PDBx:U13>
         <PDBx:U22>0.40208</PDBx:U22>
         <PDBx:U23>-0.06466</PDBx:U23>
         <PDBx:U33>0.41297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="351">
         <PDBx:U11>0.34695</PDBx:U11>
         <PDBx:U12>0.20698</PDBx:U12>
         <PDBx:U13>-0.10263</PDBx:U13>
         <PDBx:U22>0.40207</PDBx:U22>
         <PDBx:U23>-0.07625</PDBx:U23>
         <PDBx:U33>0.40962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="352">
         <PDBx:U11>0.34746</PDBx:U11>
         <PDBx:U12>0.21242</PDBx:U12>
         <PDBx:U13>-0.09095</PDBx:U13>
         <PDBx:U22>0.41212</PDBx:U22>
         <PDBx:U23>-0.08176</PDBx:U23>
         <PDBx:U33>0.41101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="353">
         <PDBx:U11>0.36397</PDBx:U11>
         <PDBx:U12>0.21675</PDBx:U12>
         <PDBx:U13>-0.11133</PDBx:U13>
         <PDBx:U22>0.42752</PDBx:U22>
         <PDBx:U23>-0.07730</PDBx:U23>
         <PDBx:U33>0.44863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="354">
         <PDBx:U11>0.37570</PDBx:U11>
         <PDBx:U12>0.22519</PDBx:U12>
         <PDBx:U13>-0.09642</PDBx:U13>
         <PDBx:U22>0.42502</PDBx:U22>
         <PDBx:U23>-0.08922</PDBx:U23>
         <PDBx:U33>0.43184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="355">
         <PDBx:U11>0.31369</PDBx:U11>
         <PDBx:U12>0.18668</PDBx:U12>
         <PDBx:U13>-0.10865</PDBx:U13>
         <PDBx:U22>0.39244</PDBx:U22>
         <PDBx:U23>-0.06117</PDBx:U23>
         <PDBx:U33>0.40228</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="356">
         <PDBx:U11>0.31378</PDBx:U11>
         <PDBx:U12>0.17973</PDBx:U12>
         <PDBx:U13>-0.11871</PDBx:U13>
         <PDBx:U22>0.38348</PDBx:U22>
         <PDBx:U23>-0.05664</PDBx:U23>
         <PDBx:U33>0.39717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="357">
         <PDBx:U11>0.35057</PDBx:U11>
         <PDBx:U12>0.18785</PDBx:U12>
         <PDBx:U13>-0.13421</PDBx:U13>
         <PDBx:U22>0.41455</PDBx:U22>
         <PDBx:U23>-0.05769</PDBx:U23>
         <PDBx:U33>0.44017</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="358">
         <PDBx:U11>0.38212</PDBx:U11>
         <PDBx:U12>0.19725</PDBx:U12>
         <PDBx:U13>-0.13509</PDBx:U13>
         <PDBx:U22>0.46551</PDBx:U22>
         <PDBx:U23>-0.05990</PDBx:U23>
         <PDBx:U33>0.49654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="359">
         <PDBx:U11>0.29166</PDBx:U11>
         <PDBx:U12>0.17136</PDBx:U12>
         <PDBx:U13>-0.11199</PDBx:U13>
         <PDBx:U22>0.38539</PDBx:U22>
         <PDBx:U23>-0.05198</PDBx:U23>
         <PDBx:U33>0.39422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="360">
         <PDBx:U11>0.29513</PDBx:U11>
         <PDBx:U12>0.16486</PDBx:U12>
         <PDBx:U13>-0.12364</PDBx:U13>
         <PDBx:U22>0.37932</PDBx:U22>
         <PDBx:U23>-0.04837</PDBx:U23>
         <PDBx:U33>0.39176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="361">
         <PDBx:U11>0.28706</PDBx:U11>
         <PDBx:U12>0.16368</PDBx:U12>
         <PDBx:U13>-0.09787</PDBx:U13>
         <PDBx:U22>0.38322</PDBx:U22>
         <PDBx:U23>-0.05018</PDBx:U23>
         <PDBx:U33>0.38141</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U23>-0.05773</PDBx:U23>
         <PDBx:U33>0.81445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>195</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="379">
         <PDBx:U11>0.40968</PDBx:U11>
         <PDBx:U12>0.18636</PDBx:U12>
         <PDBx:U13>-0.19441</PDBx:U13>
         <PDBx:U22>0.48473</PDBx:U22>
         <PDBx:U23>-0.04703</PDBx:U23>
         <PDBx:U33>0.53347</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="380">
         <PDBx:U11>0.48124</PDBx:U11>
         <PDBx:U12>0.17788</PDBx:U12>
         <PDBx:U13>-0.20780</PDBx:U13>
         <PDBx:U22>0.53918</PDBx:U22>
         <PDBx:U23>-0.04369</PDBx:U23>
         <PDBx:U33>0.58728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="381">
         <PDBx:U11>0.50567</PDBx:U11>
         <PDBx:U12>0.16662</PDBx:U12>
         <PDBx:U13>-0.20096</PDBx:U13>
         <PDBx:U22>0.58446</PDBx:U22>
         <PDBx:U23>-0.04183</PDBx:U23>
         <PDBx:U33>0.62409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="382">
         <PDBx:U11>0.43286</PDBx:U11>
         <PDBx:U12>0.16176</PDBx:U12>
         <PDBx:U13>-0.18501</PDBx:U13>
         <PDBx:U22>0.51877</PDBx:U22>
         <PDBx:U23>-0.04205</PDBx:U23>
         <PDBx:U33>0.55186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="383">
         <PDBx:U11>0.55557</PDBx:U11>
         <PDBx:U12>0.17292</PDBx:U12>
         <PDBx:U13>-0.20997</PDBx:U13>
         <PDBx:U22>0.57154</PDBx:U22>
         <PDBx:U23>-0.04287</PDBx:U23>
         <PDBx:U33>0.61946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="384">
         <PDBx:U11>0.50085</PDBx:U11>
         <PDBx:U12>0.16122</PDBx:U12>
         <PDBx:U13>-0.21850</PDBx:U13>
         <PDBx:U22>0.50020</PDBx:U22>
         <PDBx:U23>-0.03936</PDBx:U23>
         <PDBx:U33>0.54446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="385">
         <PDBx:U11>0.55781</PDBx:U11>
         <PDBx:U12>0.18320</PDBx:U12>
         <PDBx:U13>-0.22025</PDBx:U13>
         <PDBx:U22>0.55013</PDBx:U22>
         <PDBx:U23>-0.04427</PDBx:U23>
         <PDBx:U33>0.60805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="386">
         <PDBx:U11>0.48027</PDBx:U11>
         <PDBx:U12>0.16225</PDBx:U12>
         <PDBx:U13>-0.21391</PDBx:U13>
         <PDBx:U22>0.56767</PDBx:U22>
         <PDBx:U23>-0.04005</PDBx:U23>
         <PDBx:U33>0.60756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="387">
         <PDBx:U11>0.47114</PDBx:U11>
         <PDBx:U12>0.15240</PDBx:U12>
         <PDBx:U13>-0.20944</PDBx:U13>
         <PDBx:U22>0.58310</PDBx:U22>
         <PDBx:U23>-0.03915</PDBx:U23>
         <PDBx:U33>0.61666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="388">
         <PDBx:U11>0.47023</PDBx:U11>
         <PDBx:U12>0.14203</PDBx:U12>
         <PDBx:U13>-0.19701</PDBx:U13>
         <PDBx:U22>0.56956</PDBx:U22>
         <PDBx:U23>-0.03838</PDBx:U23>
         <PDBx:U33>0.59594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="389">
         <PDBx:U11>0.49406</PDBx:U11>
         <PDBx:U12>0.13856</PDBx:U12>
         <PDBx:U13>-0.18296</PDBx:U13>
         <PDBx:U22>0.61556</PDBx:U22>
         <PDBx:U23>-0.03841</PDBx:U23>
         <PDBx:U33>0.63755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="390">
         <PDBx:U11>0.58222</PDBx:U11>
         <PDBx:U12>0.14708</PDBx:U12>
         <PDBx:U13>-0.22815</PDBx:U13>
         <PDBx:U22>0.69521</PDBx:U22>
         <PDBx:U23>-0.03788</PDBx:U23>
         <PDBx:U33>0.72939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="391">
         <PDBx:U11>0.81871</PDBx:U11>
         <PDBx:U12>0.13575</PDBx:U12>
         <PDBx:U13>-0.22521</PDBx:U13>
         <PDBx:U22>0.95636</PDBx:U22>
         <PDBx:U23>-0.03790</PDBx:U23>
         <PDBx:U33>0.98485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="392">
         <PDBx:U11>0.86314</PDBx:U11>
         <PDBx:U12>0.13432</PDBx:U12>
         <PDBx:U13>-0.20913</PDBx:U13>
         <PDBx:U22>1.02452</PDBx:U22>
         <PDBx:U23>-0.03846</PDBx:U23>
         <PDBx:U33>1.05028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="393">
         <PDBx:U11>0.95334</PDBx:U11>
         <PDBx:U12>0.12761</PDBx:U12>
         <PDBx:U13>-0.23935</PDBx:U13>
         <PDBx:U22>1.08551</PDBx:U22>
         <PDBx:U23>-0.03744</PDBx:U23>
         <PDBx:U33>1.11235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="394">
         <PDBx:U11>0.43737</PDBx:U11>
         <PDBx:U12>0.13697</PDBx:U12>
         <PDBx:U13>-0.20177</PDBx:U13>
         <PDBx:U22>0.50110</PDBx:U22>
         <PDBx:U23>-0.03733</PDBx:U23>
         <PDBx:U33>0.52658</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="395">
         <PDBx:U11>0.47652</PDBx:U11>
         <PDBx:U12>0.12731</PDBx:U12>
         <PDBx:U13>-0.19110</PDBx:U13>
         <PDBx:U22>0.52968</PDBx:U22>
         <PDBx:U23>-0.03651</PDBx:U23>
         <PDBx:U33>0.54894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="396">
         <PDBx:U11>0.40736</PDBx:U11>
         <PDBx:U12>0.13066</PDBx:U12>
         <PDBx:U13>-0.17270</PDBx:U13>
         <PDBx:U22>0.46662</PDBx:U22>
         <PDBx:U23>-0.03718</PDBx:U23>
         <PDBx:U33>0.48307</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="397">
         <PDBx:U11>0.41180</PDBx:U11>
         <PDBx:U12>0.12472</PDBx:U12>
         <PDBx:U13>-0.16092</PDBx:U13>
         <PDBx:U22>0.48085</PDBx:U22>
         <PDBx:U23>-0.03641</PDBx:U23>
         <PDBx:U33>0.49211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="398">
         <PDBx:U11>0.61253</PDBx:U11>
         <PDBx:U12>0.12115</PDBx:U12>
         <PDBx:U13>-0.19883</PDBx:U13>
         <PDBx:U22>0.62573</PDBx:U22>
         <PDBx:U23>-0.03501</PDBx:U23>
         <PDBx:U33>0.64467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="399">
         <PDBx:U11>0.63889</PDBx:U11>
         <PDBx:U12>0.12608</PDBx:U12>
         <PDBx:U13>-0.19653</PDBx:U13>
         <PDBx:U22>0.62354</PDBx:U22>
         <PDBx:U23>-0.03497</PDBx:U23>
         <PDBx:U33>0.64560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="400">
         <PDBx:U11>0.64993</PDBx:U11>
         <PDBx:U12>0.11856</PDBx:U12>
         <PDBx:U13>-0.20481</PDBx:U13>
         <PDBx:U22>0.59572</PDBx:U22>
         <PDBx:U23>-0.03264</PDBx:U23>
         <PDBx:U33>0.61784</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="401">
         <PDBx:U11>0.74153</PDBx:U11>
         <PDBx:U12>0.12407</PDBx:U12>
         <PDBx:U13>-0.20984</PDBx:U13>
         <PDBx:U22>0.65993</PDBx:U22>
         <PDBx:U23>-0.03236</PDBx:U23>
         <PDBx:U33>0.68821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="402">
         <PDBx:U11>0.82920</PDBx:U11>
         <PDBx:U12>0.13142</PDBx:U12>
         <PDBx:U13>-0.22385</PDBx:U13>
         <PDBx:U22>0.74257</PDBx:U22>
         <PDBx:U23>-0.03223</PDBx:U23>
         <PDBx:U33>0.77773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="403">
         <PDBx:U11>0.92672</PDBx:U11>
         <PDBx:U12>0.13602</PDBx:U12>
         <PDBx:U13>-0.22818</PDBx:U13>
         <PDBx:U22>0.81295</PDBx:U22>
         <PDBx:U23>-0.03206</PDBx:U23>
         <PDBx:U33>0.85449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="404">
         <PDBx:U11>0.80924</PDBx:U11>
         <PDBx:U12>0.13428</PDBx:U12>
         <PDBx:U13>-0.23412</PDBx:U13>
         <PDBx:U22>0.74514</PDBx:U22>
         <PDBx:U23>-0.03225</PDBx:U23>
         <PDBx:U33>0.78129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="405">
         <PDBx:U11>0.37121</PDBx:U11>
         <PDBx:U12>0.14003</PDBx:U12>
         <PDBx:U13>-0.17065</PDBx:U13>
         <PDBx:U22>0.42495</PDBx:U22>
         <PDBx:U23>-0.03877</PDBx:U23>
         <PDBx:U33>0.44483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="406">
         <PDBx:U11>0.37592</PDBx:U11>
         <PDBx:U12>0.14246</PDBx:U12>
         <PDBx:U13>-0.15438</PDBx:U13>
         <PDBx:U22>0.43370</PDBx:U22>
         <PDBx:U23>-0.03985</PDBx:U23>
         <PDBx:U33>0.44978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="407">
         <PDBx:U11>0.34310</PDBx:U11>
         <PDBx:U12>0.14559</PDBx:U12>
         <PDBx:U13>-0.14339</PDBx:U13>
         <PDBx:U22>0.43705</PDBx:U22>
         <PDBx:U23>-0.04029</PDBx:U23>
         <PDBx:U33>0.45088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="408">
         <PDBx:U11>0.33008</PDBx:U11>
         <PDBx:U12>0.14248</PDBx:U12>
         <PDBx:U13>-0.12859</PDBx:U13>
         <PDBx:U22>0.43302</PDBx:U22>
         <PDBx:U23>-0.03951</PDBx:U23>
         <PDBx:U33>0.44089</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="409">
         <PDBx:U11>0.33473</PDBx:U11>
         <PDBx:U12>0.15025</PDBx:U12>
         <PDBx:U13>-0.15725</PDBx:U13>
         <PDBx:U22>0.37032</PDBx:U22>
         <PDBx:U23>-0.04225</PDBx:U23>
         <PDBx:U33>0.39085</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="410">
         <PDBx:U11>0.39632</PDBx:U11>
         <PDBx:U12>0.14507</PDBx:U12>
         <PDBx:U13>-0.16450</PDBx:U13>
         <PDBx:U22>0.39492</PDBx:U22>
         <PDBx:U23>-0.04105</PDBx:U23>
         <PDBx:U33>0.41699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="411">
         <PDBx:U11>0.43651</PDBx:U11>
         <PDBx:U12>0.13621</PDBx:U12>
         <PDBx:U13>-0.15618</PDBx:U13>
         <PDBx:U22>0.42301</PDBx:U22>
         <PDBx:U23>-0.03938</PDBx:U23>
         <PDBx:U33>0.43930</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="412">
         <PDBx:U11>0.48335</PDBx:U11>
         <PDBx:U12>0.14887</PDBx:U12>
         <PDBx:U13>-0.17961</PDBx:U13>
         <PDBx:U22>0.45887</PDBx:U22>
         <PDBx:U23>-0.04107</PDBx:U23>
         <PDBx:U33>0.48864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="413">
         <PDBx:U11>0.49432</PDBx:U11>
         <PDBx:U12>0.13079</PDBx:U12>
         <PDBx:U13>-0.16147</PDBx:U13>
         <PDBx:U22>0.44723</PDBx:U22>
         <PDBx:U23>-0.03793</PDBx:U23>
         <PDBx:U33>0.46510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="414">
         <PDBx:U11>0.47657</PDBx:U11>
         <PDBx:U12>0.14290</PDBx:U12>
         <PDBx:U13>-0.18520</PDBx:U13>
         <PDBx:U22>0.41645</PDBx:U22>
         <PDBx:U23>-0.03926</PDBx:U23>
         <PDBx:U33>0.44769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="415">
         <PDBx:U11>0.58733</PDBx:U11>
         <PDBx:U12>0.13354</PDBx:U12>
         <PDBx:U13>-0.17548</PDBx:U13>
         <PDBx:U22>0.51647</PDBx:U22>
         <PDBx:U23>-0.03775</PDBx:U23>
         <PDBx:U33>0.54160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="416">
         <PDBx:U11>0.67160</PDBx:U11>
         <PDBx:U12>0.12679</PDBx:U12>
         <PDBx:U13>-0.17929</PDBx:U13>
         <PDBx:U22>0.56597</PDBx:U22>
         <PDBx:U23>-0.03559</PDBx:U23>
         <PDBx:U33>0.59247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="417">
         <PDBx:U11>0.34109</PDBx:U11>
         <PDBx:U12>0.15174</PDBx:U12>
         <PDBx:U13>-0.15021</PDBx:U13>
         <PDBx:U22>0.45562</PDBx:U22>
         <PDBx:U23>-0.04119</PDBx:U23>
         <PDBx:U33>0.47435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="418">
         <PDBx:U11>0.34628</PDBx:U11>
         <PDBx:U12>0.15151</PDBx:U12>
         <PDBx:U13>-0.15033</PDBx:U13>
         <PDBx:U22>0.46102</PDBx:U22>
         <PDBx:U23>-0.04113</PDBx:U23>
         <PDBx:U33>0.47970</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="419">
         <PDBx:U11>0.35444</PDBx:U11>
         <PDBx:U12>0.15336</PDBx:U12>
         <PDBx:U13>-0.13972</PDBx:U13>
         <PDBx:U22>0.50464</PDBx:U22>
         <PDBx:U23>-0.04111</PDBx:U23>
         <PDBx:U33>0.52178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="420">
         <PDBx:U11>0.35196</PDBx:U11>
         <PDBx:U12>0.15348</PDBx:U12>
         <PDBx:U13>-0.13981</PDBx:U13>
         <PDBx:U22>0.50231</PDBx:U22>
         <PDBx:U23>-0.04114</PDBx:U23>
         <PDBx:U33>0.51952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="421">
         <PDBx:U11>0.34014</PDBx:U11>
         <PDBx:U12>0.14224</PDBx:U12>
         <PDBx:U13>-0.13303</PDBx:U13>
         <PDBx:U22>0.50493</PDBx:U22>
         <PDBx:U23>-0.03832</PDBx:U23>
         <PDBx:U33>0.51677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="422">
         <PDBx:U11>0.34252</PDBx:U11>
         <PDBx:U12>0.14253</PDBx:U12>
         <PDBx:U13>-0.13344</PDBx:U13>
         <PDBx:U22>0.50920</PDBx:U22>
         <PDBx:U23>-0.03836</PDBx:U23>
         <PDBx:U33>0.52134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="423">
         <PDBx:U11>0.30417</PDBx:U11>
         <PDBx:U12>0.14002</PDBx:U12>
         <PDBx:U13>-0.11767</PDBx:U13>
         <PDBx:U22>0.48563</PDBx:U22>
         <PDBx:U23>-0.03714</PDBx:U23>
         <PDBx:U33>0.49321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="424">
         <PDBx:U11>0.31153</PDBx:U11>
         <PDBx:U12>0.14066</PDBx:U12>
         <PDBx:U13>-0.11847</PDBx:U13>
         <PDBx:U22>0.49769</PDBx:U22>
         <PDBx:U23>-0.03725</PDBx:U23>
         <PDBx:U33>0.50601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="425">
         <PDBx:U11>0.35632</PDBx:U11>
         <PDBx:U12>0.16083</PDBx:U12>
         <PDBx:U13>-0.15010</PDBx:U13>
         <PDBx:U22>0.52716</PDBx:U22>
         <PDBx:U23>-0.04222</PDBx:U23>
         <PDBx:U33>0.55111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="426">
         <PDBx:U11>0.36178</PDBx:U11>
         <PDBx:U12>0.16182</PDBx:U12>
         <PDBx:U13>-0.15016</PDBx:U13>
         <PDBx:U22>0.53138</PDBx:U22>
         <PDBx:U23>-0.04247</PDBx:U23>
         <PDBx:U33>0.55571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U33>0.38796</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="444">
         <PDBx:U11>0.28862</PDBx:U11>
         <PDBx:U12>0.13494</PDBx:U12>
         <PDBx:U13>-0.08638</PDBx:U13>
         <PDBx:U22>0.43913</PDBx:U22>
         <PDBx:U23>-0.03513</PDBx:U23>
         <PDBx:U33>0.43178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="445">
         <PDBx:U11>0.21441</PDBx:U11>
         <PDBx:U12>0.13141</PDBx:U12>
         <PDBx:U13>-0.07599</PDBx:U13>
         <PDBx:U22>0.39496</PDBx:U22>
         <PDBx:U23>-0.03259</PDBx:U23>
         <PDBx:U33>0.38637</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="446">
         <PDBx:U11>0.26067</PDBx:U11>
         <PDBx:U12>0.12902</PDBx:U12>
         <PDBx:U13>-0.06220</PDBx:U13>
         <PDBx:U22>0.44693</PDBx:U22>
         <PDBx:U23>-0.03080</PDBx:U23>
         <PDBx:U33>0.43321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="447">
         <PDBx:U11>0.24883</PDBx:U11>
         <PDBx:U12>0.14586</PDBx:U12>
         <PDBx:U13>-0.09086</PDBx:U13>
         <PDBx:U22>0.39874</PDBx:U22>
         <PDBx:U23>-0.03943</PDBx:U23>
         <PDBx:U33>0.39522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="448">
         <PDBx:U11>0.20888</PDBx:U11>
         <PDBx:U12>0.13053</PDBx:U12>
         <PDBx:U13>-0.08285</PDBx:U13>
         <PDBx:U22>0.40863</PDBx:U22>
         <PDBx:U23>-0.03240</PDBx:U23>
         <PDBx:U33>0.40465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="449">
         <PDBx:U11>0.20697</PDBx:U11>
         <PDBx:U12>0.13046</PDBx:U12>
         <PDBx:U13>-0.08270</PDBx:U13>
         <PDBx:U22>0.40694</PDBx:U22>
         <PDBx:U23>-0.03237</PDBx:U23>
         <PDBx:U33>0.40293</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="450">
         <PDBx:U11>0.19520</PDBx:U11>
         <PDBx:U12>0.12557</PDBx:U12>
         <PDBx:U13>-0.07321</PDBx:U13>
         <PDBx:U22>0.42390</PDBx:U22>
         <PDBx:U23>-0.02988</PDBx:U23>
         <PDBx:U33>0.41955</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="451">
         <PDBx:U11>0.19483</PDBx:U11>
         <PDBx:U12>0.12563</PDBx:U12>
         <PDBx:U13>-0.07251</PDBx:U13>
         <PDBx:U22>0.42371</PDBx:U22>
         <PDBx:U23>-0.02983</PDBx:U23>
         <PDBx:U33>0.41919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="452">
         <PDBx:U11>0.25302</PDBx:U11>
         <PDBx:U12>0.11564</PDBx:U12>
         <PDBx:U13>-0.06613</PDBx:U13>
         <PDBx:U22>0.47819</PDBx:U22>
         <PDBx:U23>-0.02629</PDBx:U23>
         <PDBx:U33>0.47067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="453">
         <PDBx:U11>0.24455</PDBx:U11>
         <PDBx:U12>0.11544</PDBx:U12>
         <PDBx:U13>-0.06621</PDBx:U13>
         <PDBx:U22>0.47055</PDBx:U22>
         <PDBx:U23>-0.02625</PDBx:U23>
         <PDBx:U33>0.46314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="454">
         <PDBx:U11>0.21744</PDBx:U11>
         <PDBx:U12>0.11205</PDBx:U12>
         <PDBx:U13>-0.05188</PDBx:U13>
         <PDBx:U22>0.45647</PDBx:U22>
         <PDBx:U23>-0.02350</PDBx:U23>
         <PDBx:U33>0.44680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="455">
         <PDBx:U11>0.22009</PDBx:U11>
         <PDBx:U12>0.11144</PDBx:U12>
         <PDBx:U13>-0.05245</PDBx:U13>
         <PDBx:U22>0.46157</PDBx:U22>
         <PDBx:U23>-0.02342</PDBx:U23>
         <PDBx:U33>0.45239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="456">
         <PDBx:U11>0.20327</PDBx:U11>
         <PDBx:U12>0.12509</PDBx:U12>
         <PDBx:U13>-0.08425</PDBx:U13>
         <PDBx:U22>0.45269</PDBx:U22>
         <PDBx:U23>-0.03075</PDBx:U23>
         <PDBx:U33>0.45351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="457">
         <PDBx:U11>0.20278</PDBx:U11>
         <PDBx:U12>0.12578</PDBx:U12>
         <PDBx:U13>-0.08218</PDBx:U13>
         <PDBx:U22>0.45472</PDBx:U22>
         <PDBx:U23>-0.03070</PDBx:U23>
         <PDBx:U33>0.45539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="458">
         <PDBx:U11>0.22132</PDBx:U11>
         <PDBx:U12>0.13622</PDBx:U12>
         <PDBx:U13>-0.09280</PDBx:U13>
         <PDBx:U22>0.47388</PDBx:U22>
         <PDBx:U23>-0.03408</PDBx:U23>
         <PDBx:U33>0.47936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="459">
         <PDBx:U11>0.22451</PDBx:U11>
         <PDBx:U12>0.13670</PDBx:U12>
         <PDBx:U13>-0.08349</PDBx:U13>
         <PDBx:U22>0.49066</PDBx:U22>
         <PDBx:U23>-0.03351</PDBx:U23>
         <PDBx:U33>0.49520</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="460">
         <PDBx:U11>0.22326</PDBx:U11>
         <PDBx:U12>0.13899</PDBx:U12>
         <PDBx:U13>-0.08762</PDBx:U13>
         <PDBx:U22>0.51101</PDBx:U22>
         <PDBx:U23>-0.03417</PDBx:U23>
         <PDBx:U33>0.51927</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="461">
         <PDBx:U11>0.24566</PDBx:U11>
         <PDBx:U12>0.13975</PDBx:U12>
         <PDBx:U13>-0.06520</PDBx:U13>
         <PDBx:U22>0.52947</PDBx:U22>
         <PDBx:U23>-0.03339</PDBx:U23>
         <PDBx:U33>0.53177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="462">
         <PDBx:U11>0.37068</PDBx:U11>
         <PDBx:U12>0.15152</PDBx:U12>
         <PDBx:U13>-0.09387</PDBx:U13>
         <PDBx:U22>0.66146</PDBx:U22>
         <PDBx:U23>-0.03765</PDBx:U23>
         <PDBx:U33>0.67492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="463">
         <PDBx:U11>0.20144</PDBx:U11>
         <PDBx:U12>0.13215</PDBx:U12>
         <PDBx:U13>-0.05535</PDBx:U13>
         <PDBx:U22>0.51395</PDBx:U22>
         <PDBx:U23>-0.03024</PDBx:U23>
         <PDBx:U33>0.51608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="464">
         <PDBx:U11>0.32679</PDBx:U11>
         <PDBx:U12>0.16009</PDBx:U12>
         <PDBx:U13>-0.08259</PDBx:U13>
         <PDBx:U22>0.62769</PDBx:U22>
         <PDBx:U23>-0.03991</PDBx:U23>
         <PDBx:U33>0.64184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="465">
         <PDBx:U11>0.36901</PDBx:U11>
         <PDBx:U12>0.13401</PDBx:U12>
         <PDBx:U13>-0.05482</PDBx:U13>
         <PDBx:U22>0.71152</PDBx:U22>
         <PDBx:U23>-0.03061</PDBx:U23>
         <PDBx:U33>0.71741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="466">
         <PDBx:U11>0.23265</PDBx:U11>
         <PDBx:U12>0.15683</PDBx:U12>
         <PDBx:U13>-0.06456</PDBx:U13>
         <PDBx:U22>0.54128</PDBx:U22>
         <PDBx:U23>-0.03883</PDBx:U23>
         <PDBx:U33>0.55034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="467">
         <PDBx:U11>0.34662</PDBx:U11>
         <PDBx:U12>0.14435</PDBx:U12>
         <PDBx:U13>-0.06419</PDBx:U13>
         <PDBx:U22>0.69486</PDBx:U22>
         <PDBx:U23>-0.03402</PDBx:U23>
         <PDBx:U33>0.70543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="468">
         <PDBx:U11>0.32784</PDBx:U11>
         <PDBx:U12>0.17219</PDBx:U12>
         <PDBx:U13>-0.08959</PDBx:U13>
         <PDBx:U22>0.63067</PDBx:U22>
         <PDBx:U23>-0.04360</PDBx:U23>
         <PDBx:U33>0.65097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="469">
         <PDBx:U11>0.32374</PDBx:U11>
         <PDBx:U12>0.12541</PDBx:U12>
         <PDBx:U13>-0.04477</PDBx:U13>
         <PDBx:U22>0.69112</PDBx:U22>
         <PDBx:U23>-0.02742</PDBx:U23>
         <PDBx:U33>0.69656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="470">
         <PDBx:U11>0.23170</PDBx:U11>
         <PDBx:U12>0.11144</PDBx:U12>
         <PDBx:U13>-0.07581</PDBx:U13>
         <PDBx:U22>0.43730</PDBx:U22>
         <PDBx:U23>-0.02658</PDBx:U23>
         <PDBx:U33>0.43016</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="471">
         <PDBx:U11>0.24892</PDBx:U11>
         <PDBx:U12>0.10350</PDBx:U12>
         <PDBx:U13>-0.06947</PDBx:U13>
         <PDBx:U22>0.44948</PDBx:U22>
         <PDBx:U23>-0.02393</PDBx:U23>
         <PDBx:U33>0.44043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="472">
         <PDBx:U11>0.26097</PDBx:U11>
         <PDBx:U12>0.10455</PDBx:U12>
         <PDBx:U13>-0.05552</PDBx:U13>
         <PDBx:U22>0.45088</PDBx:U22>
         <PDBx:U23>-0.02122</PDBx:U23>
         <PDBx:U33>0.43673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="473">
         <PDBx:U11>0.22104</PDBx:U11>
         <PDBx:U12>0.09967</PDBx:U12>
         <PDBx:U13>-0.04365</PDBx:U13>
         <PDBx:U22>0.41924</PDBx:U22>
         <PDBx:U23>-0.01765</PDBx:U23>
         <PDBx:U33>0.40366</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="474">
         <PDBx:U11>0.23250</PDBx:U11>
         <PDBx:U12>0.10008</PDBx:U12>
         <PDBx:U13>-0.08328</PDBx:U13>
         <PDBx:U22>0.41106</PDBx:U22>
         <PDBx:U23>-0.02614</PDBx:U23>
         <PDBx:U33>0.40404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="475">
         <PDBx:U11>0.29247</PDBx:U11>
         <PDBx:U12>0.09349</PDBx:U12>
         <PDBx:U13>-0.07727</PDBx:U13>
         <PDBx:U22>0.46784</PDBx:U22>
         <PDBx:U23>-0.02458</PDBx:U23>
         <PDBx:U33>0.46062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>205</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="480">
         <PDBx:U11>0.21493</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02484</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="482">
         <PDBx:U11>0.34897</PDBx:U11>
         <PDBx:U12>0.12067</PDBx:U12>
         <PDBx:U13>-0.05010</PDBx:U13>
         <PDBx:U22>0.45878</PDBx:U22>
         <PDBx:U23>-0.02856</PDBx:U23>
         <PDBx:U33>0.42499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="483">
         <PDBx:U11>0.33189</PDBx:U11>
         <PDBx:U12>0.12651</PDBx:U12>
         <PDBx:U13>-0.05941</PDBx:U13>
         <PDBx:U22>0.43635</PDBx:U22>
         <PDBx:U23>-0.03258</PDBx:U23>
         <PDBx:U33>0.40710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="484">
         <PDBx:U11>0.34250</PDBx:U11>
         <PDBx:U12>0.11797</PDBx:U12>
         <PDBx:U13>-0.04629</PDBx:U13>
         <PDBx:U22>0.43997</PDBx:U22>
         <PDBx:U23>-0.02741</PDBx:U23>
         <PDBx:U33>0.40108</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="485">
         <PDBx:U11>0.26098</PDBx:U11>
         <PDBx:U12>0.11651</PDBx:U12>
         <PDBx:U13>-0.03436</PDBx:U13>
         <PDBx:U22>0.45880</PDBx:U22>
         <PDBx:U23>-0.02319</PDBx:U23>
         <PDBx:U33>0.43517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="486">
         <PDBx:U11>0.18412</PDBx:U11>
         <PDBx:U12>0.11756</PDBx:U12>
         <PDBx:U13>-0.02146</PDBx:U13>
         <PDBx:U22>0.40163</PDBx:U22>
         <PDBx:U23>-0.02312</PDBx:U23>
         <PDBx:U33>0.37469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="487">
         <PDBx:U11>0.19151</PDBx:U11>
         <PDBx:U12>0.10897</PDBx:U12>
         <PDBx:U13>-0.01216</PDBx:U13>
         <PDBx:U22>0.42358</PDBx:U22>
         <PDBx:U23>-0.01853</PDBx:U23>
         <PDBx:U33>0.39782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="488">
         <PDBx:U11>0.19734</PDBx:U11>
         <PDBx:U12>0.10681</PDBx:U12>
         <PDBx:U13>0.00033</PDBx:U13>
         <PDBx:U22>0.43471</PDBx:U22>
         <PDBx:U23>-0.01702</PDBx:U23>
         <PDBx:U33>0.40261</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="489">
         <PDBx:U11>0.22990</PDBx:U11>
         <PDBx:U12>0.12481</PDBx:U12>
         <PDBx:U13>-0.02422</PDBx:U13>
         <PDBx:U22>0.46503</PDBx:U22>
         <PDBx:U23>-0.02696</PDBx:U23>
         <PDBx:U33>0.44238</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="490">
         <PDBx:U11>0.21279</PDBx:U11>
         <PDBx:U12>0.13433</PDBx:U12>
         <PDBx:U13>-0.03087</PDBx:U13>
         <PDBx:U22>0.43308</PDBx:U22>
         <PDBx:U23>-0.03214</PDBx:U23>
         <PDBx:U33>0.40908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="491">
         <PDBx:U11>0.24334</PDBx:U11>
         <PDBx:U12>0.12443</PDBx:U12>
         <PDBx:U13>-0.00980</PDBx:U13>
         <PDBx:U22>0.50298</PDBx:U22>
         <PDBx:U23>-0.02686</PDBx:U23>
         <PDBx:U33>0.47818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="492">
         <PDBx:U11>0.19963</PDBx:U11>
         <PDBx:U12>0.14259</PDBx:U12>
         <PDBx:U13>-0.03815</PDBx:U13>
         <PDBx:U22>0.43350</PDBx:U22>
         <PDBx:U23>-0.03579</PDBx:U23>
         <PDBx:U33>0.41683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="493">
         <PDBx:U11>0.22200</PDBx:U11>
         <PDBx:U12>0.10378</PDBx:U12>
         <PDBx:U13>-0.01840</PDBx:U13>
         <PDBx:U22>0.46145</PDBx:U22>
         <PDBx:U23>-0.01674</PDBx:U23>
         <PDBx:U33>0.44246</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="494">
         <PDBx:U11>0.16080</PDBx:U11>
         <PDBx:U12>0.09499</PDBx:U12>
         <PDBx:U13>-0.00923</PDBx:U13>
         <PDBx:U22>0.41436</PDBx:U22>
         <PDBx:U23>-0.01288</PDBx:U23>
         <PDBx:U33>0.39742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="495">
         <PDBx:U11>0.13092</PDBx:U11>
         <PDBx:U12>0.09083</PDBx:U12>
         <PDBx:U13>-0.00307</PDBx:U13>
         <PDBx:U22>0.36768</PDBx:U22>
         <PDBx:U23>-0.00952</PDBx:U23>
         <PDBx:U33>0.34679</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="496">
         <PDBx:U11>0.19381</PDBx:U11>
         <PDBx:U12>0.08630</PDBx:U12>
         <PDBx:U13>0.00952</PDBx:U13>
         <PDBx:U22>0.43778</PDBx:U22>
         <PDBx:U23>-0.00672</PDBx:U23>
         <PDBx:U33>0.41329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="497">
         <PDBx:U11>0.22473</PDBx:U11>
         <PDBx:U12>0.08964</PDBx:U12>
         <PDBx:U13>-0.01876</PDBx:U13>
         <PDBx:U22>0.49109</PDBx:U22>
         <PDBx:U23>-0.01271</PDBx:U23>
         <PDBx:U33>0.48050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="498">
         <PDBx:U11>0.49410</PDBx:U11>
         <PDBx:U12>0.09123</PDBx:U12>
         <PDBx:U13>-0.02103</PDBx:U13>
         <PDBx:U22>0.78576</PDBx:U22>
         <PDBx:U23>-0.01440</PDBx:U23>
         <PDBx:U33>0.77842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="499">
         <PDBx:U11>0.70715</PDBx:U11>
         <PDBx:U12>0.08550</PDBx:U12>
         <PDBx:U13>-0.03453</PDBx:U13>
         <PDBx:U22>1.01031</PDBx:U22>
         <PDBx:U23>-0.01587</PDBx:U23>
         <PDBx:U33>1.00657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="500">
         <PDBx:U11>0.78927</PDBx:U11>
         <PDBx:U12>0.08004</PDBx:U12>
         <PDBx:U13>-0.04188</PDBx:U13>
         <PDBx:U22>1.08039</PDBx:U22>
         <PDBx:U23>-0.01683</PDBx:U23>
         <PDBx:U33>1.07739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="501">
         <PDBx:U11>0.76034</PDBx:U11>
         <PDBx:U12>0.08643</PDBx:U12>
         <PDBx:U13>-0.03860</PDBx:U13>
         <PDBx:U22>1.08701</PDBx:U22>
         <PDBx:U23>-0.01732</PDBx:U23>
         <PDBx:U33>1.08569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="502">
         <PDBx:U11>0.23550</PDBx:U11>
         <PDBx:U12>0.09227</PDBx:U12>
         <PDBx:U13>-0.01149</PDBx:U13>
         <PDBx:U22>0.45004</PDBx:U22>
         <PDBx:U23>-0.00968</PDBx:U23>
         <PDBx:U33>0.42869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="503">
         <PDBx:U11>0.17725</PDBx:U11>
         <PDBx:U12>0.08940</PDBx:U12>
         <PDBx:U13>-0.00564</PDBx:U13>
         <PDBx:U22>0.37611</PDBx:U22>
         <PDBx:U23>-0.00610</PDBx:U23>
         <PDBx:U33>0.35131</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="504">
         <PDBx:U11>0.20633</PDBx:U11>
         <PDBx:U12>0.09156</PDBx:U12>
         <PDBx:U13>0.00382</PDBx:U13>
         <PDBx:U22>0.40293</PDBx:U22>
         <PDBx:U23>-0.00508</PDBx:U23>
         <PDBx:U33>0.36830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="505">
         <PDBx:U11>0.21250</PDBx:U11>
         <PDBx:U12>0.08777</PDBx:U12>
         <PDBx:U13>0.01363</PDBx:U13>
         <PDBx:U22>0.41161</PDBx:U22>
         <PDBx:U23>-0.00062</PDBx:U23>
         <PDBx:U33>0.37188</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="506">
         <PDBx:U11>0.13444</PDBx:U11>
         <PDBx:U12>0.09123</PDBx:U12>
         <PDBx:U13>-0.01569</PDBx:U13>
         <PDBx:U22>0.31004</PDBx:U22>
         <PDBx:U23>-0.00728</PDBx:U23>
         <PDBx:U33>0.28614</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="507">
         <PDBx:U11>0.22873</PDBx:U11>
         <PDBx:U12>0.08940</PDBx:U12>
         <PDBx:U13>-0.00870</PDBx:U13>
         <PDBx:U22>0.38926</PDBx:U22>
         <PDBx:U23>-0.00347</PDBx:U23>
         <PDBx:U33>0.36164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="508">
         <PDBx:U11>0.12656</PDBx:U11>
         <PDBx:U12>0.08853</PDBx:U12>
         <PDBx:U13>-0.02520</PDBx:U13>
         <PDBx:U22>0.30413</PDBx:U22>
         <PDBx:U23>-0.00893</PDBx:U23>
         <PDBx:U33>0.28618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="509">
         <PDBx:U11>0.20916</PDBx:U11>
         <PDBx:U12>0.09802</PDBx:U12>
         <PDBx:U13>0.00030</PDBx:U13>
         <PDBx:U22>0.40126</PDBx:U22>
         <PDBx:U23>-0.00905</PDBx:U23>
         <PDBx:U33>0.36190</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="510">
         <PDBx:U11>0.17890</PDBx:U11>
         <PDBx:U12>0.10085</PDBx:U12>
         <PDBx:U13>0.00740</PDBx:U13>
         <PDBx:U22>0.36954</PDBx:U22>
         <PDBx:U23>-0.00902</PDBx:U23>
         <PDBx:U33>0.31766</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="511">
         <PDBx:U11>0.17832</PDBx:U11>
         <PDBx:U12>0.09949</PDBx:U12>
         <PDBx:U13>0.01947</PDBx:U13>
         <PDBx:U22>0.38987</PDBx:U22>
         <PDBx:U23>-0.00750</PDBx:U23>
         <PDBx:U33>0.33127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.02727</PDBx:U13>
         <PDBx:U22>0.46329</PDBx:U22>
         <PDBx:U23>-0.00398</PDBx:U23>
         <PDBx:U33>0.39200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="513">
         <PDBx:U11>0.31458</PDBx:U11>
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         <PDBx:U13>0.00120</PDBx:U13>
         <PDBx:U22>0.49844</PDBx:U22>
         <PDBx:U23>-0.01479</PDBx:U23>
         <PDBx:U33>0.44309</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="514">
         <PDBx:U11>0.35220</PDBx:U11>
         <PDBx:U12>0.10933</PDBx:U12>
         <PDBx:U13>-0.00808</PDBx:U13>
         <PDBx:U22>0.51286</PDBx:U22>
         <PDBx:U23>-0.01587</PDBx:U23>
         <PDBx:U33>0.45896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="515">
         <PDBx:U11>0.41212</PDBx:U11>
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         <PDBx:U13>-0.01524</PDBx:U13>
         <PDBx:U22>0.56717</PDBx:U22>
         <PDBx:U23>-0.02218</PDBx:U23>
         <PDBx:U33>0.51269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="516">
         <PDBx:U11>0.42046</PDBx:U11>
         <PDBx:U12>0.10694</PDBx:U12>
         <PDBx:U13>-0.00363</PDBx:U13>
         <PDBx:U22>0.57110</PDBx:U22>
         <PDBx:U23>-0.01258</PDBx:U23>
         <PDBx:U33>0.50799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="517">
         <PDBx:U11>0.19883</PDBx:U11>
         <PDBx:U12>0.09880</PDBx:U12>
         <PDBx:U13>0.02120</PDBx:U13>
         <PDBx:U22>0.42910</PDBx:U22>
         <PDBx:U23>-0.00953</PDBx:U23>
         <PDBx:U33>0.37762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="518">
         <PDBx:U11>0.22427</PDBx:U11>
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         <PDBx:U13>0.03441</PDBx:U13>
         <PDBx:U22>0.47505</PDBx:U22>
         <PDBx:U23>-0.00795</PDBx:U23>
         <PDBx:U33>0.41727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="519">
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         <PDBx:U13>0.04167</PDBx:U13>
         <PDBx:U22>0.49429</PDBx:U22>
         <PDBx:U23>-0.00065</PDBx:U23>
         <PDBx:U33>0.43360</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.48300</PDBx:U22>
         <PDBx:U23>0.00391</PDBx:U23>
         <PDBx:U33>0.40933</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="521">
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         <PDBx:U13>0.03494</PDBx:U13>
         <PDBx:U22>0.52893</PDBx:U22>
         <PDBx:U23>-0.01119</PDBx:U23>
         <PDBx:U33>0.48175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01707</PDBx:U23>
         <PDBx:U33>0.52875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01912</PDBx:U23>
         <PDBx:U33>0.81074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.92129</PDBx:U22>
         <PDBx:U23>-0.01652</PDBx:U23>
         <PDBx:U33>0.89549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:U13>0.08127</PDBx:U13>
         <PDBx:U22>0.73031</PDBx:U22>
         <PDBx:U23>0.01487</PDBx:U23>
         <PDBx:U33>0.62864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="558">
         <PDBx:U11>0.43529</PDBx:U11>
         <PDBx:U12>0.06495</PDBx:U12>
         <PDBx:U13>0.09734</PDBx:U13>
         <PDBx:U22>0.71862</PDBx:U22>
         <PDBx:U23>0.03483</PDBx:U23>
         <PDBx:U33>0.60922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="559">
         <PDBx:U11>0.20330</PDBx:U11>
         <PDBx:U12>0.07578</PDBx:U12>
         <PDBx:U13>0.07232</PDBx:U13>
         <PDBx:U22>0.43290</PDBx:U22>
         <PDBx:U23>0.04210</PDBx:U23>
         <PDBx:U33>0.33301</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="560">
         <PDBx:U11>0.23039</PDBx:U11>
         <PDBx:U12>0.07337</PDBx:U12>
         <PDBx:U13>0.07397</PDBx:U13>
         <PDBx:U22>0.44734</PDBx:U22>
         <PDBx:U23>0.05363</PDBx:U23>
         <PDBx:U33>0.35310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="561">
         <PDBx:U11>0.24422</PDBx:U11>
         <PDBx:U12>0.07995</PDBx:U12>
         <PDBx:U13>0.07192</PDBx:U13>
         <PDBx:U22>0.45284</PDBx:U22>
         <PDBx:U23>0.05938</PDBx:U23>
         <PDBx:U33>0.34462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="562">
         <PDBx:U11>0.20347</PDBx:U11>
         <PDBx:U12>0.07947</PDBx:U12>
         <PDBx:U13>0.07699</PDBx:U13>
         <PDBx:U22>0.40832</PDBx:U22>
         <PDBx:U23>0.07203</PDBx:U23>
         <PDBx:U33>0.29834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="563">
         <PDBx:U11>0.21751</PDBx:U11>
         <PDBx:U12>0.07120</PDBx:U12>
         <PDBx:U13>0.06633</PDBx:U13>
         <PDBx:U22>0.42148</PDBx:U22>
         <PDBx:U23>0.05007</PDBx:U23>
         <PDBx:U33>0.34706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="564">
         <PDBx:U11>0.22985</PDBx:U11>
         <PDBx:U12>0.06523</PDBx:U12>
         <PDBx:U13>0.06784</PDBx:U13>
         <PDBx:U22>0.44497</PDBx:U22>
         <PDBx:U23>0.04560</PDBx:U23>
         <PDBx:U33>0.38143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="565">
         <PDBx:U11>0.26425</PDBx:U11>
         <PDBx:U12>0.06926</PDBx:U12>
         <PDBx:U13>0.06914</PDBx:U13>
         <PDBx:U22>0.45397</PDBx:U22>
         <PDBx:U23>0.06136</PDBx:U23>
         <PDBx:U33>0.38979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="566">
         <PDBx:U11>0.18911</PDBx:U11>
         <PDBx:U12>0.08620</PDBx:U12>
         <PDBx:U13>0.06430</PDBx:U13>
         <PDBx:U22>0.39486</PDBx:U22>
         <PDBx:U23>0.05088</PDBx:U23>
         <PDBx:U33>0.27765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="567">
         <PDBx:U11>0.24591</PDBx:U11>
         <PDBx:U12>0.09234</PDBx:U12>
         <PDBx:U13>0.06065</PDBx:U13>
         <PDBx:U22>0.44541</PDBx:U22>
         <PDBx:U23>0.05454</PDBx:U23>
         <PDBx:U33>0.31426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="568">
         <PDBx:U11>0.24987</PDBx:U11>
         <PDBx:U12>0.09830</PDBx:U12>
         <PDBx:U13>0.06128</PDBx:U13>
         <PDBx:U22>0.45970</PDBx:U22>
         <PDBx:U23>0.04828</PDBx:U23>
         <PDBx:U33>0.30772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="569">
         <PDBx:U11>0.28159</PDBx:U11>
         <PDBx:U12>0.10278</PDBx:U12>
         <PDBx:U13>0.05331</PDBx:U13>
         <PDBx:U22>0.48516</PDBx:U22>
         <PDBx:U23>0.03965</PDBx:U23>
         <PDBx:U33>0.33048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="570">
         <PDBx:U11>0.22590</PDBx:U11>
         <PDBx:U12>0.09268</PDBx:U12>
         <PDBx:U13>0.05023</PDBx:U13>
         <PDBx:U22>0.40759</PDBx:U22>
         <PDBx:U23>0.04975</PDBx:U23>
         <PDBx:U33>0.28908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="571">
         <PDBx:U11>0.30458</PDBx:U11>
         <PDBx:U12>0.09805</PDBx:U12>
         <PDBx:U13>0.04604</PDBx:U13>
         <PDBx:U22>0.48157</PDBx:U22>
         <PDBx:U23>0.05254</PDBx:U23>
         <PDBx:U33>0.34965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="572">
         <PDBx:U11>0.27651</PDBx:U11>
         <PDBx:U12>0.10226</PDBx:U12>
         <PDBx:U13>0.05101</PDBx:U13>
         <PDBx:U22>0.46369</PDBx:U22>
         <PDBx:U23>0.06124</PDBx:U23>
         <PDBx:U33>0.31325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="573">
         <PDBx:U11>0.27164</PDBx:U11>
         <PDBx:U12>0.09784</PDBx:U12>
         <PDBx:U13>0.03801</PDBx:U13>
         <PDBx:U22>0.43578</PDBx:U22>
         <PDBx:U23>0.04622</PDBx:U23>
         <PDBx:U33>0.31102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="606">
         <PDBx:U11>0.39500</PDBx:U11>
         <PDBx:U12>0.11886</PDBx:U12>
         <PDBx:U13>0.04833</PDBx:U13>
         <PDBx:U22>0.59521</PDBx:U22>
         <PDBx:U23>0.08488</PDBx:U23>
         <PDBx:U33>0.39863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="607">
         <PDBx:U11>0.36353</PDBx:U11>
         <PDBx:U12>0.11158</PDBx:U12>
         <PDBx:U13>0.03871</PDBx:U13>
         <PDBx:U22>0.53789</PDBx:U22>
         <PDBx:U23>0.08611</PDBx:U23>
         <PDBx:U33>0.37692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>221</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="608">
         <PDBx:U11>0.22230</PDBx:U11>
         <PDBx:U12>0.09946</PDBx:U12>
         <PDBx:U13>0.02892</PDBx:U13>
         <PDBx:U22>0.37005</PDBx:U22>
         <PDBx:U23>0.04942</PDBx:U23>
         <PDBx:U33>0.24399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="609">
         <PDBx:U11>0.24396</PDBx:U11>
         <PDBx:U12>0.09346</PDBx:U12>
         <PDBx:U13>0.02506</PDBx:U13>
         <PDBx:U22>0.37576</PDBx:U22>
         <PDBx:U23>0.04451</PDBx:U23>
         <PDBx:U33>0.27195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="610">
         <PDBx:U11>0.29744</PDBx:U11>
         <PDBx:U12>0.09310</PDBx:U12>
         <PDBx:U13>0.01848</PDBx:U13>
         <PDBx:U22>0.42144</PDBx:U22>
         <PDBx:U23>0.03309</PDBx:U23>
         <PDBx:U33>0.32021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="611">
         <PDBx:U11>0.37457</PDBx:U11>
         <PDBx:U12>0.08891</PDBx:U12>
         <PDBx:U13>0.01598</PDBx:U13>
         <PDBx:U22>0.48718</PDBx:U22>
         <PDBx:U23>0.02912</PDBx:U23>
         <PDBx:U33>0.40222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="612">
         <PDBx:U11>0.26932</PDBx:U11>
         <PDBx:U12>0.08892</PDBx:U12>
         <PDBx:U13>0.02940</PDBx:U13>
         <PDBx:U22>0.39782</PDBx:U22>
         <PDBx:U23>0.04689</PDBx:U23>
         <PDBx:U33>0.31152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="613">
         <PDBx:U11>0.28667</PDBx:U11>
         <PDBx:U12>0.08878</PDBx:U12>
         <PDBx:U13>0.03561</PDBx:U13>
         <PDBx:U22>0.41710</PDBx:U22>
         <PDBx:U23>0.05896</PDBx:U23>
         <PDBx:U33>0.33512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="614">
         <PDBx:U11>0.36934</PDBx:U11>
         <PDBx:U12>0.08715</PDBx:U12>
         <PDBx:U13>0.03488</PDBx:U13>
         <PDBx:U22>0.48997</PDBx:U22>
         <PDBx:U23>0.06237</PDBx:U23>
         <PDBx:U33>0.42006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="615">
         <PDBx:U11>0.25307</PDBx:U11>
         <PDBx:U12>0.09064</PDBx:U12>
         <PDBx:U13>0.04279</PDBx:U13>
         <PDBx:U22>0.39556</PDBx:U22>
         <PDBx:U23>0.06746</PDBx:U23>
         <PDBx:U33>0.30624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="616">
         <PDBx:U11>0.39592</PDBx:U11>
         <PDBx:U12>0.08819</PDBx:U12>
         <PDBx:U13>0.04041</PDBx:U13>
         <PDBx:U22>0.51716</PDBx:U22>
         <PDBx:U23>0.07422</PDBx:U23>
         <PDBx:U33>0.45343</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="617">
         <PDBx:U11>0.32243</PDBx:U11>
         <PDBx:U12>0.09143</PDBx:U12>
         <PDBx:U13>0.04901</PDBx:U13>
         <PDBx:U22>0.46562</PDBx:U22>
         <PDBx:U23>0.08083</PDBx:U23>
         <PDBx:U33>0.38172</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="618">
         <PDBx:U11>0.44553</PDBx:U11>
         <PDBx:U12>0.09070</PDBx:U12>
         <PDBx:U13>0.04736</PDBx:U13>
         <PDBx:U22>0.57721</PDBx:U22>
         <PDBx:U23>0.08431</PDBx:U23>
         <PDBx:U33>0.50695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="619">
         <PDBx:U11>0.25961</PDBx:U11>
         <PDBx:U12>0.09843</PDBx:U12>
         <PDBx:U13>0.01598</PDBx:U13>
         <PDBx:U22>0.38956</PDBx:U22>
         <PDBx:U23>0.02819</PDBx:U23>
         <PDBx:U33>0.27193</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="620">
         <PDBx:U11>0.29352</PDBx:U11>
         <PDBx:U12>0.09971</PDBx:U12>
         <PDBx:U13>0.00916</PDBx:U13>
         <PDBx:U22>0.41452</PDBx:U22>
         <PDBx:U23>0.01877</PDBx:U23>
         <PDBx:U33>0.29780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="621">
         <PDBx:U11>0.29400</PDBx:U11>
         <PDBx:U12>0.09729</PDBx:U12>
         <PDBx:U13>0.00635</PDBx:U13>
         <PDBx:U22>0.40688</PDBx:U22>
         <PDBx:U23>0.01248</PDBx:U23>
         <PDBx:U33>0.30465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="622">
         <PDBx:U11>0.27296</PDBx:U11>
         <PDBx:U12>0.09647</PDBx:U12>
         <PDBx:U13>0.00096</PDBx:U13>
         <PDBx:U22>0.37406</PDBx:U22>
         <PDBx:U23>0.00741</PDBx:U23>
         <PDBx:U33>0.27894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="623">
         <PDBx:U11>0.26070</PDBx:U11>
         <PDBx:U12>0.09743</PDBx:U12>
         <PDBx:U13>0.00549</PDBx:U13>
         <PDBx:U22>0.37285</PDBx:U22>
         <PDBx:U23>0.01904</PDBx:U23>
         <PDBx:U33>0.26109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="624">
         <PDBx:U11>0.31161</PDBx:U11>
         <PDBx:U12>0.10076</PDBx:U12>
         <PDBx:U13>0.00626</PDBx:U13>
         <PDBx:U22>0.43340</PDBx:U22>
         <PDBx:U23>0.02472</PDBx:U23>
         <PDBx:U33>0.30642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="625">
         <PDBx:U11>0.33615</PDBx:U11>
         <PDBx:U12>0.09836</PDBx:U12>
         <PDBx:U13>0.00152</PDBx:U13>
         <PDBx:U22>0.45171</PDBx:U22>
         <PDBx:U23>0.02416</PDBx:U23>
         <PDBx:U33>0.33072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="626">
         <PDBx:U11>0.38997</PDBx:U11>
         <PDBx:U12>0.10278</PDBx:U12>
         <PDBx:U13>-0.00064</PDBx:U13>
         <PDBx:U22>0.51608</PDBx:U22>
         <PDBx:U23>0.02702</PDBx:U23>
         <PDBx:U33>0.37738</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="627">
         <PDBx:U11>0.41598</PDBx:U11>
         <PDBx:U12>0.10893</PDBx:U12>
         <PDBx:U13>-0.00482</PDBx:U13>
         <PDBx:U22>0.54641</PDBx:U22>
         <PDBx:U23>0.02089</PDBx:U23>
         <PDBx:U33>0.38984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="628">
         <PDBx:U11>0.32116</PDBx:U11>
         <PDBx:U12>0.11197</PDBx:U12>
         <PDBx:U13>-0.00706</PDBx:U13>
         <PDBx:U22>0.44516</PDBx:U22>
         <PDBx:U23>0.01147</PDBx:U23>
         <PDBx:U33>0.28780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="629">
         <PDBx:U11>0.44148</PDBx:U11>
         <PDBx:U12>0.11225</PDBx:U12>
         <PDBx:U13>-0.00775</PDBx:U13>
         <PDBx:U22>0.58159</PDBx:U22>
         <PDBx:U23>0.02394</PDBx:U23>
         <PDBx:U33>0.40851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="630">
         <PDBx:U11>0.24994</PDBx:U11>
         <PDBx:U12>0.09684</PDBx:U12>
         <PDBx:U13>0.00960</PDBx:U13>
         <PDBx:U22>0.37013</PDBx:U22>
         <PDBx:U23>0.01289</PDBx:U23>
         <PDBx:U33>0.27134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="631">
         <PDBx:U11>0.35799</PDBx:U11>
         <PDBx:U12>0.09706</PDBx:U12>
         <PDBx:U13>0.00561</PDBx:U13>
         <PDBx:U22>0.47468</PDBx:U22>
         <PDBx:U23>0.00630</PDBx:U23>
         <PDBx:U33>0.38522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="632">
         <PDBx:U11>0.34491</PDBx:U11>
         <PDBx:U12>0.10383</PDBx:U12>
         <PDBx:U13>0.00411</PDBx:U13>
         <PDBx:U22>0.46855</PDBx:U22>
         <PDBx:U23>0.00037</PDBx:U23>
         <PDBx:U33>0.36699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="633">
         <PDBx:U11>0.28527</PDBx:U11>
         <PDBx:U12>0.10759</PDBx:U12>
         <PDBx:U13>0.00887</PDBx:U13>
         <PDBx:U22>0.42123</PDBx:U22>
         <PDBx:U23>0.00221</PDBx:U23>
         <PDBx:U33>0.30455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="634">
         <PDBx:U11>0.32562</PDBx:U11>
         <PDBx:U12>0.09381</PDBx:U12>
         <PDBx:U13>0.00914</PDBx:U13>
         <PDBx:U22>0.44907</PDBx:U22>
         <PDBx:U23>0.00853</PDBx:U23>
         <PDBx:U33>0.37005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="635">
         <PDBx:U11>0.33963</PDBx:U11>
         <PDBx:U12>0.08752</PDBx:U12>
         <PDBx:U13>0.01147</PDBx:U13>
         <PDBx:U22>0.45461</PDBx:U22>
         <PDBx:U23>0.01427</PDBx:U23>
         <PDBx:U33>0.39027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="636">
         <PDBx:U11>0.25602</PDBx:U11>
         <PDBx:U12>0.10628</PDBx:U12>
         <PDBx:U13>-0.00246</PDBx:U13>
         <PDBx:U22>0.37155</PDBx:U22>
         <PDBx:U23>-0.00662</PDBx:U23>
         <PDBx:U33>0.27584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="637">
         <PDBx:U11>0.33830</PDBx:U11>
         <PDBx:U12>0.11389</PDBx:U12>
         <PDBx:U13>-0.00429</PDBx:U13>
         <PDBx:U22>0.45855</PDBx:U22>
         <PDBx:U23>-0.01327</PDBx:U23>
         <PDBx:U33>0.35344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="638">
         <PDBx:U11>0.24130</PDBx:U11>
         <PDBx:U12>0.11577</PDBx:U12>
         <PDBx:U13>0.00238</PDBx:U13>
         <PDBx:U22>0.37998</PDBx:U22>
         <PDBx:U23>-0.01261</PDBx:U23>
         <PDBx:U33>0.27104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="639">
         <PDBx:U11>0.31953</PDBx:U11>
         <PDBx:U12>0.11147</PDBx:U12>
         <PDBx:U13>0.00502</PDBx:U13>
         <PDBx:U22>0.46429</PDBx:U22>
         <PDBx:U23>-0.00968</PDBx:U23>
         <PDBx:U33>0.36565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="640">
         <PDBx:U11>0.43164</PDBx:U11>
         <PDBx:U12>0.11641</PDBx:U12>
         <PDBx:U13>-0.01296</PDBx:U13>
         <PDBx:U22>0.53889</PDBx:U22>
         <PDBx:U23>-0.01998</PDBx:U23>
         <PDBx:U33>0.44387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="641">
         <PDBx:U11>0.33180</PDBx:U11>
         <PDBx:U12>0.11393</PDBx:U12>
         <PDBx:U13>-0.01457</PDBx:U13>
         <PDBx:U22>0.44160</PDBx:U22>
         <PDBx:U23>-0.01945</PDBx:U23>
         <PDBx:U33>0.36042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="642">
         <PDBx:U11>0.54090</PDBx:U11>
         <PDBx:U12>0.12541</PDBx:U12>
         <PDBx:U13>-0.01558</PDBx:U13>
         <PDBx:U22>0.64953</PDBx:U22>
         <PDBx:U23>-0.02755</PDBx:U23>
         <PDBx:U33>0.54600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="643">
         <PDBx:U11>0.24437</PDBx:U11>
         <PDBx:U12>0.12242</PDBx:U12>
         <PDBx:U13>0.00567</PDBx:U13>
         <PDBx:U22>0.39292</PDBx:U22>
         <PDBx:U23>-0.01574</PDBx:U23>
         <PDBx:U33>0.26862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="644">
         <PDBx:U11>0.24093</PDBx:U11>
         <PDBx:U12>0.12238</PDBx:U12>
         <PDBx:U13>0.00579</PDBx:U13>
         <PDBx:U22>0.38962</PDBx:U22>
         <PDBx:U23>-0.01562</PDBx:U23>
         <PDBx:U33>0.26508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="645">
         <PDBx:U11>0.25456</PDBx:U11>
         <PDBx:U12>0.12426</PDBx:U12>
         <PDBx:U13>0.01405</PDBx:U13>
         <PDBx:U22>0.42212</PDBx:U22>
         <PDBx:U23>-0.01541</PDBx:U23>
         <PDBx:U33>0.29215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="646">
         <PDBx:U11>0.25494</PDBx:U11>
         <PDBx:U12>0.12433</PDBx:U12>
         <PDBx:U13>0.01413</PDBx:U13>
         <PDBx:U22>0.42265</PDBx:U22>
         <PDBx:U23>-0.01541</PDBx:U23>
         <PDBx:U33>0.29244</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="647">
         <PDBx:U11>0.28769</PDBx:U11>
         <PDBx:U12>0.12996</PDBx:U12>
         <PDBx:U13>0.01167</PDBx:U13>
         <PDBx:U22>0.45896</PDBx:U22>
         <PDBx:U23>-0.02368</PDBx:U23>
         <PDBx:U33>0.33597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="648">
         <PDBx:U11>0.28925</PDBx:U11>
         <PDBx:U12>0.12993</PDBx:U12>
         <PDBx:U13>0.01154</PDBx:U13>
         <PDBx:U22>0.46027</PDBx:U22>
         <PDBx:U23>-0.02369</PDBx:U23>
         <PDBx:U33>0.33747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="649">
         <PDBx:U11>0.25420</PDBx:U11>
         <PDBx:U12>0.13719</PDBx:U12>
         <PDBx:U13>0.00785</PDBx:U13>
         <PDBx:U22>0.42016</PDBx:U22>
         <PDBx:U23>-0.03047</PDBx:U23>
         <PDBx:U33>0.29166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="650">
         <PDBx:U11>0.25497</PDBx:U11>
         <PDBx:U12>0.13707</PDBx:U12>
         <PDBx:U13>0.00740</PDBx:U13>
         <PDBx:U22>0.42015</PDBx:U22>
         <PDBx:U23>-0.03049</PDBx:U23>
         <PDBx:U33>0.29232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="651">
         <PDBx:U11>0.31449</PDBx:U11>
         <PDBx:U12>0.12847</PDBx:U12>
         <PDBx:U13>0.02074</PDBx:U13>
         <PDBx:U22>0.49241</PDBx:U22>
         <PDBx:U23>-0.01340</PDBx:U23>
         <PDBx:U33>0.33948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="652">
         <PDBx:U11>0.31281</PDBx:U11>
         <PDBx:U12>0.12874</PDBx:U12>
         <PDBx:U13>0.02085</PDBx:U13>
         <PDBx:U22>0.49109</PDBx:U22>
         <PDBx:U23>-0.01365</PDBx:U23>
         <PDBx:U33>0.33778</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="653">
         <PDBx:U11>0.32648</PDBx:U11>
         <PDBx:U12>0.12422</PDBx:U12>
         <PDBx:U13>0.02320</PDBx:U13>
         <PDBx:U22>0.50372</PDBx:U22>
         <PDBx:U23>-0.00362</PDBx:U23>
         <PDBx:U33>0.34317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="654">
         <PDBx:U11>0.32602</PDBx:U11>
         <PDBx:U12>0.13029</PDBx:U12>
         <PDBx:U13>0.03176</PDBx:U13>
         <PDBx:U22>0.52445</PDBx:U22>
         <PDBx:U23>-0.01367</PDBx:U23>
         <PDBx:U33>0.36310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="655">
         <PDBx:U11>0.40831</PDBx:U11>
         <PDBx:U12>0.12950</PDBx:U12>
         <PDBx:U13>0.02918</PDBx:U13>
         <PDBx:U22>0.59740</PDBx:U22>
         <PDBx:U23>-0.00070</PDBx:U23>
         <PDBx:U33>0.41145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="656">
         <PDBx:U11>0.43095</PDBx:U11>
         <PDBx:U12>0.13527</PDBx:U12>
         <PDBx:U13>0.03856</PDBx:U13>
         <PDBx:U22>0.63873</PDBx:U22>
         <PDBx:U23>-0.01256</PDBx:U23>
         <PDBx:U33>0.45178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="657">
         <PDBx:U11>0.40724</PDBx:U11>
         <PDBx:U12>0.12802</PDBx:U12>
         <PDBx:U13>0.03858</PDBx:U13>
         <PDBx:U22>0.61018</PDBx:U22>
         <PDBx:U23>0.00507</PDBx:U23>
         <PDBx:U33>0.41585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="658">
         <PDBx:U11>0.41133</PDBx:U11>
         <PDBx:U12>0.13698</PDBx:U12>
         <PDBx:U13>0.03512</PDBx:U13>
         <PDBx:U22>0.61301</PDBx:U22>
         <PDBx:U23>-0.00932</PDBx:U23>
         <PDBx:U33>0.41363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="659">
         <PDBx:U11>0.40244</PDBx:U11>
         <PDBx:U12>0.13564</PDBx:U12>
         <PDBx:U13>0.02389</PDBx:U13>
         <PDBx:U22>0.58614</PDBx:U22>
         <PDBx:U23>-0.00471</PDBx:U23>
         <PDBx:U33>0.38697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="660">
         <PDBx:U11>0.49887</PDBx:U11>
         <PDBx:U12>0.13766</PDBx:U12>
         <PDBx:U13>0.04860</PDBx:U13>
         <PDBx:U22>0.72222</PDBx:U22>
         <PDBx:U23>-0.01554</PDBx:U23>
         <PDBx:U33>0.52692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="661">
         <PDBx:U11>0.24769</PDBx:U11>
         <PDBx:U12>0.12730</PDBx:U12>
         <PDBx:U13>0.01355</PDBx:U13>
         <PDBx:U22>0.42836</PDBx:U22>
         <PDBx:U23>-0.02320</PDBx:U23>
         <PDBx:U33>0.31816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="662">
         <PDBx:U11>0.18950</PDBx:U11>
         <PDBx:U12>0.13341</PDBx:U12>
         <PDBx:U13>0.01232</PDBx:U13>
         <PDBx:U22>0.37823</PDBx:U22>
         <PDBx:U23>-0.03001</PDBx:U23>
         <PDBx:U33>0.27515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="663">
         <PDBx:U11>0.32445</PDBx:U11>
         <PDBx:U12>0.13750</PDBx:U12>
         <PDBx:U13>0.02379</PDBx:U13>
         <PDBx:U22>0.53281</PDBx:U22>
         <PDBx:U23>-0.03229</PDBx:U23>
         <PDBx:U33>0.41756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="664">
         <PDBx:U11>0.28687</PDBx:U11>
         <PDBx:U12>0.13261</PDBx:U12>
         <PDBx:U13>0.03345</PDBx:U13>
         <PDBx:U22>0.50776</PDBx:U22>
         <PDBx:U23>-0.02702</PDBx:U23>
         <PDBx:U33>0.38549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="665">
         <PDBx:U11>0.25275</PDBx:U11>
         <PDBx:U12>0.12931</PDBx:U12>
         <PDBx:U13>0.00907</PDBx:U13>
         <PDBx:U22>0.44625</PDBx:U22>
         <PDBx:U23>-0.02833</PDBx:U23>
         <PDBx:U33>0.36099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="666">
         <PDBx:U11>0.24457</PDBx:U11>
         <PDBx:U12>0.13591</PDBx:U12>
         <PDBx:U13>0.00799</PDBx:U13>
         <PDBx:U22>0.45107</PDBx:U22>
         <PDBx:U23>-0.03404</PDBx:U23>
         <PDBx:U33>0.37429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="667">
         <PDBx:U11>0.36299</PDBx:U11>
         <PDBx:U12>0.13024</PDBx:U12>
         <PDBx:U13>0.00278</PDBx:U13>
         <PDBx:U22>0.57735</PDBx:U22>
         <PDBx:U23>-0.03045</PDBx:U23>
         <PDBx:U33>0.51855</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="668">
         <PDBx:U11>0.36390</PDBx:U11>
         <PDBx:U12>0.12191</PDBx:U12>
         <PDBx:U13>0.01678</PDBx:U13>
         <PDBx:U22>0.59779</PDBx:U22>
         <PDBx:U23>-0.02494</PDBx:U23>
         <PDBx:U33>0.53517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="669">
         <PDBx:U11>0.28603</PDBx:U11>
         <PDBx:U12>0.14658</PDBx:U12>
         <PDBx:U13>0.02341</PDBx:U13>
         <PDBx:U22>0.49659</PDBx:U22>
         <PDBx:U23>-0.04031</PDBx:U23>
         <PDBx:U33>0.37896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="670">
         <PDBx:U11>0.34044</PDBx:U11>
         <PDBx:U12>0.15130</PDBx:U12>
         <PDBx:U13>0.03545</PDBx:U13>
         <PDBx:U22>0.56894</PDBx:U22>
         <PDBx:U23>-0.04407</PDBx:U23>
         <PDBx:U33>0.43969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>228</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:U33>0.37777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="769">
         <PDBx:U11>0.23327</PDBx:U11>
         <PDBx:U12>0.16558</PDBx:U12>
         <PDBx:U13>-0.03311</PDBx:U13>
         <PDBx:U22>0.40194</PDBx:U22>
         <PDBx:U23>-0.05403</PDBx:U23>
         <PDBx:U33>0.35772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="770">
         <PDBx:U11>0.23840</PDBx:U11>
         <PDBx:U12>0.16834</PDBx:U12>
         <PDBx:U13>-0.02808</PDBx:U13>
         <PDBx:U22>0.39767</PDBx:U22>
         <PDBx:U23>-0.05772</PDBx:U23>
         <PDBx:U33>0.34055</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="771">
         <PDBx:U11>0.31291</PDBx:U11>
         <PDBx:U12>0.16966</PDBx:U12>
         <PDBx:U13>-0.03562</PDBx:U13>
         <PDBx:U22>0.45020</PDBx:U22>
         <PDBx:U23>-0.05991</PDBx:U23>
         <PDBx:U33>0.39232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="772">
         <PDBx:U11>0.22626</PDBx:U11>
         <PDBx:U12>0.15461</PDBx:U12>
         <PDBx:U13>-0.03671</PDBx:U13>
         <PDBx:U22>0.38488</PDBx:U22>
         <PDBx:U23>-0.04731</PDBx:U23>
         <PDBx:U33>0.34206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="773">
         <PDBx:U11>0.26210</PDBx:U11>
         <PDBx:U12>0.15284</PDBx:U12>
         <PDBx:U13>-0.04496</PDBx:U13>
         <PDBx:U22>0.42653</PDBx:U22>
         <PDBx:U23>-0.04479</PDBx:U23>
         <PDBx:U33>0.39538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="774">
         <PDBx:U11>0.20314</PDBx:U11>
         <PDBx:U12>0.14685</PDBx:U12>
         <PDBx:U13>-0.02476</PDBx:U13>
         <PDBx:U22>0.37224</PDBx:U22>
         <PDBx:U23>-0.04246</PDBx:U23>
         <PDBx:U33>0.32031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="775">
         <PDBx:U11>0.27899</PDBx:U11>
         <PDBx:U12>0.14338</PDBx:U12>
         <PDBx:U13>-0.04995</PDBx:U13>
         <PDBx:U22>0.42961</PDBx:U22>
         <PDBx:U23>-0.03973</PDBx:U23>
         <PDBx:U33>0.40000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="776">
         <PDBx:U11>0.23733</PDBx:U11>
         <PDBx:U12>0.16892</PDBx:U12>
         <PDBx:U13>-0.01554</PDBx:U13>
         <PDBx:U22>0.41315</PDBx:U22>
         <PDBx:U23>-0.05838</PDBx:U23>
         <PDBx:U33>0.34506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="777">
         <PDBx:U11>0.24438</PDBx:U11>
         <PDBx:U12>0.17209</PDBx:U12>
         <PDBx:U13>-0.01077</PDBx:U13>
         <PDBx:U22>0.41424</PDBx:U22>
         <PDBx:U23>-0.06200</PDBx:U23>
         <PDBx:U33>0.33092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="778">
         <PDBx:U11>0.22949</PDBx:U11>
         <PDBx:U12>0.16253</PDBx:U12>
         <PDBx:U13>-0.00695</PDBx:U13>
         <PDBx:U22>0.39587</PDBx:U22>
         <PDBx:U23>-0.05527</PDBx:U23>
         <PDBx:U33>0.30109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="779">
         <PDBx:U11>0.26672</PDBx:U11>
         <PDBx:U12>0.15582</PDBx:U12>
         <PDBx:U13>0.00075</PDBx:U13>
         <PDBx:U22>0.44712</PDBx:U22>
         <PDBx:U23>-0.04945</PDBx:U23>
         <PDBx:U33>0.35020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="780">
         <PDBx:U11>0.25646</PDBx:U11>
         <PDBx:U12>0.17915</PDBx:U12>
         <PDBx:U13>0.00105</PDBx:U13>
         <PDBx:U22>0.44559</PDBx:U22>
         <PDBx:U23>-0.06720</PDBx:U23>
         <PDBx:U33>0.35444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="781">
         <PDBx:U11>0.26819</PDBx:U11>
         <PDBx:U12>0.18382</PDBx:U12>
         <PDBx:U13>0.00365</PDBx:U13>
         <PDBx:U22>0.44839</PDBx:U22>
         <PDBx:U23>-0.07214</PDBx:U23>
         <PDBx:U33>0.34097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="782">
         <PDBx:U11>0.27086</PDBx:U11>
         <PDBx:U12>0.18891</PDBx:U12>
         <PDBx:U13>-0.00130</PDBx:U13>
         <PDBx:U22>0.46747</PDBx:U22>
         <PDBx:U23>-0.07312</PDBx:U23>
         <PDBx:U33>0.39028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="783">
         <PDBx:U11>0.23167</PDBx:U11>
         <PDBx:U12>0.16249</PDBx:U12>
         <PDBx:U13>-0.01209</PDBx:U13>
         <PDBx:U22>0.38009</PDBx:U22>
         <PDBx:U23>-0.05619</PDBx:U23>
         <PDBx:U33>0.27831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>241</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="784">
         <PDBx:U11>0.22866</PDBx:U11>
         <PDBx:U12>0.15496</PDBx:U12>
         <PDBx:U13>-0.00980</PDBx:U13>
         <PDBx:U22>0.37278</PDBx:U22>
         <PDBx:U23>-0.04999</PDBx:U23>
         <PDBx:U33>0.26056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>241</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.04740</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.03957</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.03342</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.03506</PDBx:U23>
         <PDBx:U33>0.25017</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>246</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="850">
         <PDBx:U11>0.30862</PDBx:U11>
         <PDBx:U12>0.08588</PDBx:U12>
         <PDBx:U13>-0.04942</PDBx:U13>
         <PDBx:U22>0.26155</PDBx:U22>
         <PDBx:U23>-0.02337</PDBx:U23>
         <PDBx:U33>0.21191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="851">
         <PDBx:U11>0.32533</PDBx:U11>
         <PDBx:U12>0.08518</PDBx:U12>
         <PDBx:U13>-0.04656</PDBx:U13>
         <PDBx:U22>0.27220</PDBx:U22>
         <PDBx:U23>-0.02082</PDBx:U23>
         <PDBx:U33>0.22902</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="852">
         <PDBx:U11>0.26642</PDBx:U11>
         <PDBx:U12>0.09398</PDBx:U12>
         <PDBx:U13>-0.04629</PDBx:U13>
         <PDBx:U22>0.24886</PDBx:U22>
         <PDBx:U23>-0.02142</PDBx:U23>
         <PDBx:U33>0.18677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="853">
         <PDBx:U11>0.39716</PDBx:U11>
         <PDBx:U12>0.08676</PDBx:U12>
         <PDBx:U13>-0.06820</PDBx:U13>
         <PDBx:U22>0.28218</PDBx:U22>
         <PDBx:U23>-0.03049</PDBx:U23>
         <PDBx:U33>0.25251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="854">
         <PDBx:U11>0.40743</PDBx:U11>
         <PDBx:U12>0.07971</PDBx:U12>
         <PDBx:U13>-0.07352</PDBx:U13>
         <PDBx:U22>0.25800</PDBx:U22>
         <PDBx:U23>-0.03041</PDBx:U23>
         <PDBx:U33>0.23896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="855">
         <PDBx:U11>0.50370</PDBx:U11>
         <PDBx:U12>0.08222</PDBx:U12>
         <PDBx:U13>-0.08302</PDBx:U13>
         <PDBx:U22>0.33226</PDBx:U22>
         <PDBx:U23>-0.03561</PDBx:U23>
         <PDBx:U33>0.31835</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="856">
         <PDBx:U11>0.50411</PDBx:U11>
         <PDBx:U12>0.07094</PDBx:U12>
         <PDBx:U13>-0.08378</PDBx:U13>
         <PDBx:U22>0.30923</PDBx:U22>
         <PDBx:U23>-0.03543</PDBx:U23>
         <PDBx:U33>0.30235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="857">
         <PDBx:U11>0.40739</PDBx:U11>
         <PDBx:U12>0.08526</PDBx:U12>
         <PDBx:U13>-0.07880</PDBx:U13>
         <PDBx:U22>0.24854</PDBx:U22>
         <PDBx:U23>-0.02902</PDBx:U23>
         <PDBx:U33>0.23312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="858">
         <PDBx:U11>0.52941</PDBx:U11>
         <PDBx:U12>0.08133</PDBx:U12>
         <PDBx:U13>-0.08790</PDBx:U13>
         <PDBx:U22>0.33219</PDBx:U22>
         <PDBx:U23>-0.02872</PDBx:U23>
         <PDBx:U33>0.32677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="859">
         <PDBx:U11>0.57647</PDBx:U11>
         <PDBx:U12>0.06663</PDBx:U12>
         <PDBx:U13>-0.08296</PDBx:U13>
         <PDBx:U22>0.35917</PDBx:U22>
         <PDBx:U23>-0.02470</PDBx:U23>
         <PDBx:U33>0.35720</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="860">
         <PDBx:U11>0.61699</PDBx:U11>
         <PDBx:U12>0.08999</PDBx:U12>
         <PDBx:U13>-0.09742</PDBx:U13>
         <PDBx:U22>0.40597</PDBx:U22>
         <PDBx:U23>-0.03355</PDBx:U23>
         <PDBx:U33>0.40908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="861">
         <PDBx:U11>0.71258</PDBx:U11>
         <PDBx:U12>0.06218</PDBx:U12>
         <PDBx:U13>-0.09112</PDBx:U13>
         <PDBx:U22>0.45807</PDBx:U22>
         <PDBx:U23>-0.02320</PDBx:U23>
         <PDBx:U33>0.46449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="862">
         <PDBx:U11>0.73966</PDBx:U11>
         <PDBx:U12>0.08562</PDBx:U12>
         <PDBx:U13>-0.10507</PDBx:U13>
         <PDBx:U22>0.49406</PDBx:U22>
         <PDBx:U23>-0.03305</PDBx:U23>
         <PDBx:U33>0.50771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="863">
         <PDBx:U11>0.73786</PDBx:U11>
         <PDBx:U12>0.07264</PDBx:U12>
         <PDBx:U13>-0.10260</PDBx:U13>
         <PDBx:U22>0.46836</PDBx:U22>
         <PDBx:U23>-0.02580</PDBx:U23>
         <PDBx:U33>0.48585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="864">
         <PDBx:U11>0.88311</PDBx:U11>
         <PDBx:U12>0.06655</PDBx:U12>
         <PDBx:U13>-0.10881</PDBx:U13>
         <PDBx:U22>0.58410</PDBx:U22>
         <PDBx:U23>-0.02351</PDBx:U23>
         <PDBx:U33>0.60875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="865">
         <PDBx:U11>0.40619</PDBx:U11>
         <PDBx:U12>0.09673</PDBx:U12>
         <PDBx:U13>-0.08968</PDBx:U13>
         <PDBx:U22>0.24093</PDBx:U22>
         <PDBx:U23>-0.04069</PDBx:U23>
         <PDBx:U33>0.22445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="866">
         <PDBx:U11>0.52270</PDBx:U11>
         <PDBx:U12>0.10015</PDBx:U12>
         <PDBx:U13>-0.09771</PDBx:U13>
         <PDBx:U22>0.33604</PDBx:U22>
         <PDBx:U23>-0.04587</PDBx:U23>
         <PDBx:U33>0.32717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="867">
         <PDBx:U11>0.53852</PDBx:U11>
         <PDBx:U12>0.09012</PDBx:U12>
         <PDBx:U13>-0.09465</PDBx:U13>
         <PDBx:U22>0.35352</PDBx:U22>
         <PDBx:U23>-0.04825</PDBx:U23>
         <PDBx:U33>0.34094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="868">
         <PDBx:U11>0.53071</PDBx:U11>
         <PDBx:U12>0.08319</PDBx:U12>
         <PDBx:U13>-0.09878</PDBx:U13>
         <PDBx:U22>0.32094</PDBx:U22>
         <PDBx:U23>-0.04922</PDBx:U23>
         <PDBx:U33>0.31852</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="869">
         <PDBx:U11>0.46240</PDBx:U11>
         <PDBx:U12>0.11598</PDBx:U12>
         <PDBx:U13>-0.10170</PDBx:U13>
         <PDBx:U22>0.29028</PDBx:U22>
         <PDBx:U23>-0.05091</PDBx:U23>
         <PDBx:U33>0.27652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="870">
         <PDBx:U11>0.69383</PDBx:U11>
         <PDBx:U12>0.11800</PDBx:U12>
         <PDBx:U13>-0.10578</PDBx:U13>
         <PDBx:U22>0.51659</PDBx:U22>
         <PDBx:U23>-0.05290</PDBx:U23>
         <PDBx:U33>0.50487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="871">
         <PDBx:U11>0.77395</PDBx:U11>
         <PDBx:U12>0.11387</PDBx:U12>
         <PDBx:U13>-0.11320</PDBx:U13>
         <PDBx:U22>0.56831</PDBx:U22>
         <PDBx:U23>-0.05040</PDBx:U23>
         <PDBx:U33>0.56713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="872">
         <PDBx:U11>0.76707</PDBx:U11>
         <PDBx:U12>0.12241</PDBx:U12>
         <PDBx:U13>-0.10079</PDBx:U13>
         <PDBx:U22>0.61532</PDBx:U22>
         <PDBx:U23>-0.05420</PDBx:U23>
         <PDBx:U33>0.59691</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="873">
         <PDBx:U11>0.47976</PDBx:U11>
         <PDBx:U12>0.08800</PDBx:U12>
         <PDBx:U13>-0.08716</PDBx:U13>
         <PDBx:U22>0.32562</PDBx:U22>
         <PDBx:U23>-0.04727</PDBx:U23>
         <PDBx:U33>0.29970</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="874">
         <PDBx:U11>0.47330</PDBx:U11>
         <PDBx:U12>0.07849</PDBx:U12>
         <PDBx:U13>-0.08591</PDBx:U13>
         <PDBx:U22>0.32400</PDBx:U22>
         <PDBx:U23>-0.04923</PDBx:U23>
         <PDBx:U33>0.29404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="875">
         <PDBx:U11>0.56088</PDBx:U11>
         <PDBx:U12>0.06075</PDBx:U12>
         <PDBx:U13>-0.08279</PDBx:U13>
         <PDBx:U22>0.39478</PDBx:U22>
         <PDBx:U23>-0.04561</PDBx:U23>
         <PDBx:U33>0.37454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="876">
         <PDBx:U11>0.50125</PDBx:U11>
         <PDBx:U12>0.05181</PDBx:U12>
         <PDBx:U13>-0.08670</PDBx:U13>
         <PDBx:U22>0.31839</PDBx:U22>
         <PDBx:U23>-0.04910</PDBx:U23>
         <PDBx:U33>0.30350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="877">
         <PDBx:U11>0.42201</PDBx:U11>
         <PDBx:U12>0.08036</PDBx:U12>
         <PDBx:U13>-0.07920</PDBx:U13>
         <PDBx:U22>0.31058</PDBx:U22>
         <PDBx:U23>-0.04672</PDBx:U23>
         <PDBx:U33>0.26517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="878">
         <PDBx:U11>0.42865</PDBx:U11>
         <PDBx:U12>0.07318</PDBx:U12>
         <PDBx:U13>-0.08108</PDBx:U13>
         <PDBx:U22>0.32433</PDBx:U22>
         <PDBx:U23>-0.04962</PDBx:U23>
         <PDBx:U33>0.27256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="879">
         <PDBx:U11>0.43180</PDBx:U11>
         <PDBx:U12>0.05770</PDBx:U12>
         <PDBx:U13>-0.07785</PDBx:U13>
         <PDBx:U22>0.32834</PDBx:U22>
         <PDBx:U23>-0.04638</PDBx:U23>
         <PDBx:U33>0.28126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="880">
         <PDBx:U11>0.46610</PDBx:U11>
         <PDBx:U12>0.08145</PDBx:U12>
         <PDBx:U13>-0.08635</PDBx:U13>
         <PDBx:U22>0.36713</PDBx:U22>
         <PDBx:U23>-0.05638</PDBx:U23>
         <PDBx:U33>0.30453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="881">
         <PDBx:U11>0.47877</PDBx:U11>
         <PDBx:U12>0.05035</PDBx:U12>
         <PDBx:U13>-0.08143</PDBx:U13>
         <PDBx:U22>0.38297</PDBx:U22>
         <PDBx:U23>-0.04935</PDBx:U23>
         <PDBx:U33>0.33044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="882">
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="883">
         <PDBx:U11>0.48904</PDBx:U11>
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         <PDBx:U23>-0.05594</PDBx:U23>
         <PDBx:U33>0.33332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="884">
         <PDBx:U11>0.44984</PDBx:U11>
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         <PDBx:U23>-0.03909</PDBx:U23>
         <PDBx:U33>0.27030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="885">
         <PDBx:U11>0.45924</PDBx:U11>
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         <PDBx:U13>-0.06950</PDBx:U13>
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         <PDBx:U23>-0.03584</PDBx:U23>
         <PDBx:U33>0.27227</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="886">
         <PDBx:U11>0.49288</PDBx:U11>
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         <PDBx:U13>-0.07747</PDBx:U13>
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         <PDBx:U23>-0.03783</PDBx:U23>
         <PDBx:U33>0.27649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="887">
         <PDBx:U11>0.53684</PDBx:U11>
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         <PDBx:U13>-0.07658</PDBx:U13>
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         <PDBx:U23>-0.03821</PDBx:U23>
         <PDBx:U33>0.31076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="888">
         <PDBx:U11>0.45507</PDBx:U11>
         <PDBx:U12>0.03407</PDBx:U12>
         <PDBx:U13>-0.05935</PDBx:U13>
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         <PDBx:U23>-0.02979</PDBx:U23>
         <PDBx:U33>0.27617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="889">
         <PDBx:U11>0.42335</PDBx:U11>
         <PDBx:U12>0.03583</PDBx:U12>
         <PDBx:U13>-0.05048</PDBx:U13>
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         <PDBx:U23>-0.02712</PDBx:U23>
         <PDBx:U33>0.27397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="890">
         <PDBx:U11>0.48246</PDBx:U11>
         <PDBx:U12>0.01710</PDBx:U12>
         <PDBx:U13>-0.05310</PDBx:U13>
         <PDBx:U22>0.29026</PDBx:U22>
         <PDBx:U23>-0.02705</PDBx:U23>
         <PDBx:U33>0.28927</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="891">
         <PDBx:U11>0.46075</PDBx:U11>
         <PDBx:U12>0.03530</PDBx:U12>
         <PDBx:U13>-0.04084</PDBx:U13>
         <PDBx:U22>0.33704</PDBx:U22>
         <PDBx:U23>-0.02242</PDBx:U23>
         <PDBx:U33>0.31965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="892">
         <PDBx:U11>0.50591</PDBx:U11>
         <PDBx:U12>0.04517</PDBx:U12>
         <PDBx:U13>-0.08564</PDBx:U13>
         <PDBx:U22>0.26924</PDBx:U22>
         <PDBx:U23>-0.03876</PDBx:U23>
         <PDBx:U33>0.27594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="893">
         <PDBx:U11>0.59879</PDBx:U11>
         <PDBx:U12>0.04301</PDBx:U12>
         <PDBx:U13>-0.09375</PDBx:U13>
         <PDBx:U22>0.32342</PDBx:U22>
         <PDBx:U23>-0.03800</PDBx:U23>
         <PDBx:U33>0.34345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="894">
         <PDBx:U11>0.65736</PDBx:U11>
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         <PDBx:U13>-0.09903</PDBx:U13>
         <PDBx:U22>0.37288</PDBx:U22>
         <PDBx:U23>-0.04236</PDBx:U23>
         <PDBx:U33>0.39807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="895">
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         <PDBx:U23>-0.04083</PDBx:U23>
         <PDBx:U33>0.39181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="896">
         <PDBx:U11>0.66253</PDBx:U11>
         <PDBx:U12>0.05834</PDBx:U12>
         <PDBx:U13>-0.10122</PDBx:U13>
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         <PDBx:U23>-0.03541</PDBx:U23>
         <PDBx:U33>0.40504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="897">
         <PDBx:U11>0.83610</PDBx:U11>
         <PDBx:U12>0.05878</PDBx:U12>
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         <PDBx:U23>-0.03206</PDBx:U23>
         <PDBx:U33>0.55587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="898">
         <PDBx:U11>0.94736</PDBx:U11>
         <PDBx:U12>0.07072</PDBx:U12>
         <PDBx:U13>-0.11970</PDBx:U13>
         <PDBx:U22>0.62932</PDBx:U22>
         <PDBx:U23>-0.02914</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.04160</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.03201</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="922">
         <PDBx:U11>0.69872</PDBx:U11>
         <PDBx:U12>-0.01743</PDBx:U12>
         <PDBx:U13>-0.06692</PDBx:U13>
         <PDBx:U22>0.41881</PDBx:U22>
         <PDBx:U23>-0.03323</PDBx:U23>
         <PDBx:U33>0.44604</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="923">
         <PDBx:U11>0.61863</PDBx:U11>
         <PDBx:U12>-0.02090</PDBx:U12>
         <PDBx:U13>-0.05394</PDBx:U13>
         <PDBx:U22>0.35776</PDBx:U22>
         <PDBx:U23>-0.02811</PDBx:U23>
         <PDBx:U33>0.37931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="924">
         <PDBx:U11>0.58498</PDBx:U11>
         <PDBx:U12>-0.03091</PDBx:U12>
         <PDBx:U13>-0.04256</PDBx:U13>
         <PDBx:U22>0.35769</PDBx:U22>
         <PDBx:U23>-0.02777</PDBx:U23>
         <PDBx:U33>0.37531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="925">
         <PDBx:U11>0.61236</PDBx:U11>
         <PDBx:U12>-0.03947</PDBx:U12>
         <PDBx:U13>-0.02937</PDBx:U13>
         <PDBx:U22>0.39413</PDBx:U22>
         <PDBx:U23>-0.02426</PDBx:U23>
         <PDBx:U33>0.41143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.74622</PDBx:U11>
         <PDBx:U12>-0.03134</PDBx:U12>
         <PDBx:U13>-0.04953</PDBx:U13>
         <PDBx:U22>0.45200</PDBx:U22>
         <PDBx:U23>-0.02341</PDBx:U23>
         <PDBx:U33>0.47958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="927">
         <PDBx:U11>0.84444</PDBx:U11>
         <PDBx:U12>-0.01994</PDBx:U12>
         <PDBx:U13>-0.06194</PDBx:U13>
         <PDBx:U22>0.52024</PDBx:U22>
         <PDBx:U23>-0.02256</PDBx:U23>
         <PDBx:U33>0.55138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.00216</PDBx:U12>
         <PDBx:U13>-0.06707</PDBx:U13>
         <PDBx:U22>0.56809</PDBx:U22>
         <PDBx:U23>-0.02316</PDBx:U23>
         <PDBx:U33>0.59284</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>1.00502</PDBx:U11>
         <PDBx:U12>-0.02638</PDBx:U12>
         <PDBx:U13>-0.06857</PDBx:U13>
         <PDBx:U22>0.64021</PDBx:U22>
         <PDBx:U23>-0.02000</PDBx:U23>
         <PDBx:U33>0.68084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02193</PDBx:U23>
         <PDBx:U33>0.70839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:U12>-0.04595</PDBx:U12>
         <PDBx:U13>-0.01141</PDBx:U13>
         <PDBx:U22>0.44949</PDBx:U22>
         <PDBx:U23>-0.02399</PDBx:U23>
         <PDBx:U33>0.45812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="948">
         <PDBx:U11>0.38685</PDBx:U11>
         <PDBx:U12>0.00654</PDBx:U12>
         <PDBx:U13>-0.02479</PDBx:U13>
         <PDBx:U22>0.34830</PDBx:U22>
         <PDBx:U23>-0.01935</PDBx:U23>
         <PDBx:U33>0.32754</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="949">
         <PDBx:U11>0.32328</PDBx:U11>
         <PDBx:U12>0.01450</PDBx:U12>
         <PDBx:U13>-0.03067</PDBx:U13>
         <PDBx:U22>0.31318</PDBx:U22>
         <PDBx:U23>-0.01823</PDBx:U23>
         <PDBx:U33>0.28233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="950">
         <PDBx:U11>0.28055</PDBx:U11>
         <PDBx:U12>0.00794</PDBx:U12>
         <PDBx:U13>-0.02441</PDBx:U13>
         <PDBx:U22>0.29751</PDBx:U22>
         <PDBx:U23>-0.01485</PDBx:U23>
         <PDBx:U33>0.27009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="951">
         <PDBx:U11>0.37831</PDBx:U11>
         <PDBx:U12>0.00233</PDBx:U12>
         <PDBx:U13>-0.01211</PDBx:U13>
         <PDBx:U22>0.39801</PDBx:U22>
         <PDBx:U23>-0.01248</PDBx:U23>
         <PDBx:U33>0.38018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="952">
         <PDBx:U11>0.26014</PDBx:U11>
         <PDBx:U12>0.02981</PDBx:U12>
         <PDBx:U13>-0.03050</PDBx:U13>
         <PDBx:U22>0.26155</PDBx:U22>
         <PDBx:U23>-0.01503</PDBx:U23>
         <PDBx:U33>0.22309</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="953">
         <PDBx:U11>0.29736</PDBx:U11>
         <PDBx:U12>0.03837</PDBx:U12>
         <PDBx:U13>-0.03734</PDBx:U13>
         <PDBx:U22>0.27921</PDBx:U22>
         <PDBx:U23>-0.01858</PDBx:U23>
         <PDBx:U33>0.23657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="954">
         <PDBx:U11>0.35641</PDBx:U11>
         <PDBx:U12>0.04341</PDBx:U12>
         <PDBx:U13>-0.04814</PDBx:U13>
         <PDBx:U22>0.33474</PDBx:U22>
         <PDBx:U23>-0.02344</PDBx:U23>
         <PDBx:U33>0.28322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="955">
         <PDBx:U11>0.29265</PDBx:U11>
         <PDBx:U12>0.04167</PDBx:U12>
         <PDBx:U13>-0.03325</PDBx:U13>
         <PDBx:U22>0.25975</PDBx:U22>
         <PDBx:U23>-0.01768</PDBx:U23>
         <PDBx:U33>0.22227</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="956">
         <PDBx:U11>0.41961</PDBx:U11>
         <PDBx:U12>0.05263</PDBx:U12>
         <PDBx:U13>-0.05367</PDBx:U13>
         <PDBx:U22>0.38098</PDBx:U22>
         <PDBx:U23>-0.02739</PDBx:U23>
         <PDBx:U33>0.32745</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="957">
         <PDBx:U11>0.34167</PDBx:U11>
         <PDBx:U12>0.05051</PDBx:U12>
         <PDBx:U13>-0.04063</PDBx:U13>
         <PDBx:U22>0.29281</PDBx:U22>
         <PDBx:U23>-0.02103</PDBx:U23>
         <PDBx:U33>0.25274</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="958">
         <PDBx:U11>0.37810</PDBx:U11>
         <PDBx:U12>0.05651</PDBx:U12>
         <PDBx:U13>-0.05019</PDBx:U13>
         <PDBx:U22>0.32718</PDBx:U22>
         <PDBx:U23>-0.02584</PDBx:U23>
         <PDBx:U33>0.27988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="959">
         <PDBx:U11>0.33274</PDBx:U11>
         <PDBx:U12>0.00876</PDBx:U12>
         <PDBx:U13>-0.03336</PDBx:U13>
         <PDBx:U22>0.36952</PDBx:U22>
         <PDBx:U23>-0.01516</PDBx:U23>
         <PDBx:U33>0.33403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="960">
         <PDBx:U11>0.36819</PDBx:U11>
         <PDBx:U12>0.00587</PDBx:U12>
         <PDBx:U13>-0.03116</PDBx:U13>
         <PDBx:U22>0.43607</PDBx:U22>
         <PDBx:U23>-0.01124</PDBx:U23>
         <PDBx:U33>0.40216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="961">
         <PDBx:U11>0.25866</PDBx:U11>
         <PDBx:U12>0.01686</PDBx:U12>
         <PDBx:U13>-0.02295</PDBx:U13>
         <PDBx:U22>0.34456</PDBx:U22>
         <PDBx:U23>-0.00439</PDBx:U23>
         <PDBx:U33>0.31231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="962">
         <PDBx:U11>0.24708</PDBx:U11>
         <PDBx:U12>0.02836</PDBx:U12>
         <PDBx:U13>-0.02409</PDBx:U13>
         <PDBx:U22>0.32931</PDBx:U22>
         <PDBx:U23>-0.00240</PDBx:U23>
         <PDBx:U33>0.29044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="963">
         <PDBx:U11>0.43799</PDBx:U11>
         <PDBx:U12>0.00744</PDBx:U12>
         <PDBx:U13>-0.04580</PDBx:U13>
         <PDBx:U22>0.52132</PDBx:U22>
         <PDBx:U23>-0.01257</PDBx:U23>
         <PDBx:U33>0.47445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="964">
         <PDBx:U11>0.60804</PDBx:U11>
         <PDBx:U12>-0.00488</PDBx:U12>
         <PDBx:U13>-0.04999</PDBx:U13>
         <PDBx:U22>0.70882</PDBx:U22>
         <PDBx:U23>-0.01373</PDBx:U23>
         <PDBx:U33>0.66518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="965">
         <PDBx:U11>0.76076</PDBx:U11>
         <PDBx:U12>-0.00343</PDBx:U12>
         <PDBx:U13>-0.06686</PDBx:U13>
         <PDBx:U22>0.86892</PDBx:U22>
         <PDBx:U23>-0.01671</PDBx:U23>
         <PDBx:U33>0.80961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="966">
         <PDBx:U11>0.77762</PDBx:U11>
         <PDBx:U12>0.01214</PDBx:U12>
         <PDBx:U13>-0.07176</PDBx:U13>
         <PDBx:U22>0.89888</PDBx:U22>
         <PDBx:U23>-0.01208</PDBx:U23>
         <PDBx:U33>0.82456</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="967">
         <PDBx:U11>0.83032</PDBx:U11>
         <PDBx:U12>0.01559</PDBx:U12>
         <PDBx:U13>-0.08531</PDBx:U13>
         <PDBx:U22>0.96101</PDBx:U22>
         <PDBx:U23>-0.01327</PDBx:U23>
         <PDBx:U33>0.86948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="968">
         <PDBx:U11>0.77939</PDBx:U11>
         <PDBx:U12>0.00467</PDBx:U12>
         <PDBx:U13>-0.09632</PDBx:U13>
         <PDBx:U22>0.90774</PDBx:U22>
         <PDBx:U23>-0.01973</PDBx:U23>
         <PDBx:U33>0.81263</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="969">
         <PDBx:U11>0.77599</PDBx:U11>
         <PDBx:U12>0.02899</PDBx:U12>
         <PDBx:U13>-0.08773</PDBx:U13>
         <PDBx:U22>0.91733</PDBx:U22>
         <PDBx:U23>-0.00811</PDBx:U23>
         <PDBx:U33>0.81166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="970">
         <PDBx:U11>0.24925</PDBx:U11>
         <PDBx:U12>0.01327</PDBx:U12>
         <PDBx:U13>-0.01444</PDBx:U13>
         <PDBx:U22>0.35527</PDBx:U22>
         <PDBx:U23>-0.00096</PDBx:U23>
         <PDBx:U33>0.33302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="971">
         <PDBx:U11>0.29673</PDBx:U11>
         <PDBx:U12>0.02288</PDBx:U12>
         <PDBx:U13>-0.00473</PDBx:U13>
         <PDBx:U22>0.41459</PDBx:U22>
         <PDBx:U23>0.00492</PDBx:U23>
         <PDBx:U33>0.39850</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="972">
         <PDBx:U11>0.23412</PDBx:U11>
         <PDBx:U12>0.03663</PDBx:U12>
         <PDBx:U13>-0.01333</PDBx:U13>
         <PDBx:U22>0.36736</PDBx:U22>
         <PDBx:U23>0.01063</PDBx:U23>
         <PDBx:U33>0.33997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="973">
         <PDBx:U11>0.25570</PDBx:U11>
         <PDBx:U12>0.04593</PDBx:U12>
         <PDBx:U13>-0.00810</PDBx:U13>
         <PDBx:U22>0.38622</PDBx:U22>
         <PDBx:U23>0.01444</PDBx:U23>
         <PDBx:U33>0.35994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="974">
         <PDBx:U11>0.26269</PDBx:U11>
         <PDBx:U12>0.01775</PDBx:U12>
         <PDBx:U13>0.00555</PDBx:U13>
         <PDBx:U22>0.40083</PDBx:U22>
         <PDBx:U23>0.00685</PDBx:U23>
         <PDBx:U33>0.39878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="975">
         <PDBx:U11>0.25123</PDBx:U11>
         <PDBx:U12>0.02675</PDBx:U12>
         <PDBx:U13>0.01801</PDBx:U13>
         <PDBx:U22>0.39550</PDBx:U22>
         <PDBx:U23>0.01146</PDBx:U23>
         <PDBx:U33>0.40412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="976">
         <PDBx:U11>0.32082</PDBx:U11>
         <PDBx:U12>0.02668</PDBx:U12>
         <PDBx:U13>0.02678</PDBx:U13>
         <PDBx:U22>0.43615</PDBx:U22>
         <PDBx:U23>0.00869</PDBx:U23>
         <PDBx:U33>0.44693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="977">
         <PDBx:U11>0.30655</PDBx:U11>
         <PDBx:U12>0.02141</PDBx:U12>
         <PDBx:U13>0.02978</PDBx:U13>
         <PDBx:U22>0.46941</PDBx:U22>
         <PDBx:U23>0.01153</PDBx:U23>
         <PDBx:U33>0.49368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="978">
         <PDBx:U11>0.18919</PDBx:U11>
         <PDBx:U12>0.03721</PDBx:U12>
         <PDBx:U13>-0.02659</PDBx:U13>
         <PDBx:U22>0.33763</PDBx:U22>
         <PDBx:U23>0.01135</PDBx:U23>
         <PDBx:U33>0.29858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="979">
         <PDBx:U11>0.25701</PDBx:U11>
         <PDBx:U12>0.04957</PDBx:U12>
         <PDBx:U13>-0.03404</PDBx:U13>
         <PDBx:U22>0.41888</PDBx:U22>
         <PDBx:U23>0.01762</PDBx:U23>
         <PDBx:U33>0.36716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="980">
         <PDBx:U11>0.22585</PDBx:U11>
         <PDBx:U12>0.05643</PDBx:U12>
         <PDBx:U13>-0.03577</PDBx:U13>
         <PDBx:U22>0.36931</PDBx:U22>
         <PDBx:U23>0.01561</PDBx:U23>
         <PDBx:U33>0.30625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="981">
         <PDBx:U11>0.21760</PDBx:U11>
         <PDBx:U12>0.06664</PDBx:U12>
         <PDBx:U13>-0.03494</PDBx:U13>
         <PDBx:U22>0.36699</PDBx:U22>
         <PDBx:U23>0.02142</PDBx:U23>
         <PDBx:U33>0.29809</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="982">
         <PDBx:U11>0.34773</PDBx:U11>
         <PDBx:U12>0.04805</PDBx:U12>
         <PDBx:U13>-0.04889</PDBx:U13>
         <PDBx:U22>0.52843</PDBx:U22>
         <PDBx:U23>0.01851</PDBx:U23>
         <PDBx:U33>0.46407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="983">
         <PDBx:U11>0.34788</PDBx:U11>
         <PDBx:U12>0.04803</PDBx:U12>
         <PDBx:U13>-0.04895</PDBx:U13>
         <PDBx:U22>0.52840</PDBx:U22>
         <PDBx:U23>0.01845</PDBx:U23>
         <PDBx:U33>0.46393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="984">
         <PDBx:U11>0.44323</PDBx:U11>
         <PDBx:U12>0.03742</PDBx:U12>
         <PDBx:U13>-0.05743</PDBx:U13>
         <PDBx:U22>0.61089</PDBx:U22>
         <PDBx:U23>0.00942</PDBx:U23>
         <PDBx:U33>0.53994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="985">
         <PDBx:U11>0.36432</PDBx:U11>
         <PDBx:U12>0.04355</PDBx:U12>
         <PDBx:U13>-0.04886</PDBx:U13>
         <PDBx:U22>0.56987</PDBx:U22>
         <PDBx:U23>0.02191</PDBx:U23>
         <PDBx:U33>0.51656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="986">
         <PDBx:U11>0.51412</PDBx:U11>
         <PDBx:U12>0.02612</PDBx:U12>
         <PDBx:U13>-0.05145</PDBx:U13>
         <PDBx:U22>0.67135</PDBx:U22>
         <PDBx:U23>0.00442</PDBx:U23>
         <PDBx:U33>0.61297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="987">
         <PDBx:U11>0.31093</PDBx:U11>
         <PDBx:U12>0.04798</PDBx:U12>
         <PDBx:U13>-0.03815</PDBx:U13>
         <PDBx:U22>0.52610</PDBx:U22>
         <PDBx:U23>0.02711</PDBx:U23>
         <PDBx:U33>0.48776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="988">
         <PDBx:U11>0.50308</PDBx:U11>
         <PDBx:U12>0.03997</PDBx:U12>
         <PDBx:U13>-0.06956</PDBx:U13>
         <PDBx:U22>0.66939</PDBx:U22>
         <PDBx:U23>0.00715</PDBx:U23>
         <PDBx:U33>0.58081</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="989">
         <PDBx:U11>0.43150</PDBx:U11>
         <PDBx:U12>0.03560</PDBx:U12>
         <PDBx:U13>-0.05980</PDBx:U13>
         <PDBx:U22>0.64752</PDBx:U22>
         <PDBx:U23>0.01889</PDBx:U23>
         <PDBx:U33>0.58864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="990">
         <PDBx:U11>0.19877</PDBx:U11>
         <PDBx:U12>0.05106</PDBx:U12>
         <PDBx:U13>-0.03778</PDBx:U13>
         <PDBx:U22>0.31975</PDBx:U22>
         <PDBx:U23>0.00766</PDBx:U23>
         <PDBx:U33>0.25478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="991">
         <PDBx:U11>0.21814</PDBx:U11>
         <PDBx:U12>0.05844</PDBx:U12>
         <PDBx:U13>-0.03862</PDBx:U13>
         <PDBx:U22>0.32295</PDBx:U22>
         <PDBx:U23>0.00521</PDBx:U23>
         <PDBx:U33>0.25000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="992">
         <PDBx:U11>0.22478</PDBx:U11>
         <PDBx:U12>0.06128</PDBx:U12>
         <PDBx:U13>-0.02715</PDBx:U13>
         <PDBx:U22>0.31941</PDBx:U22>
         <PDBx:U23>0.00716</PDBx:U23>
         <PDBx:U33>0.25782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="993">
         <PDBx:U11>0.20831</PDBx:U11>
         <PDBx:U12>0.07010</PDBx:U12>
         <PDBx:U13>-0.02579</PDBx:U13>
         <PDBx:U22>0.30285</PDBx:U22>
         <PDBx:U23>0.00952</PDBx:U23>
         <PDBx:U33>0.23595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="994">
         <PDBx:U11>0.28240</PDBx:U11>
         <PDBx:U12>0.05342</PDBx:U12>
         <PDBx:U13>-0.04570</PDBx:U13>
         <PDBx:U22>0.36522</PDBx:U22>
         <PDBx:U23>-0.00385</PDBx:U23>
         <PDBx:U33>0.28854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="995">
         <PDBx:U11>0.32973</PDBx:U11>
         <PDBx:U12>0.05357</PDBx:U12>
         <PDBx:U13>-0.05807</PDBx:U13>
         <PDBx:U22>0.41915</PDBx:U22>
         <PDBx:U23>-0.00711</PDBx:U23>
         <PDBx:U33>0.32708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="996">
         <PDBx:U11>0.36172</PDBx:U11>
         <PDBx:U12>0.04916</PDBx:U12>
         <PDBx:U13>-0.06574</PDBx:U13>
         <PDBx:U22>0.43181</PDBx:U22>
         <PDBx:U23>-0.01587</PDBx:U23>
         <PDBx:U33>0.33667</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="997">
         <PDBx:U11>0.35832</PDBx:U11>
         <PDBx:U12>0.05738</PDBx:U12>
         <PDBx:U13>-0.06458</PDBx:U13>
         <PDBx:U22>0.46986</PDBx:U22>
         <PDBx:U23>-0.00287</PDBx:U23>
         <PDBx:U33>0.36445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="998">
         <PDBx:U11>0.36816</PDBx:U11>
         <PDBx:U12>0.04986</PDBx:U12>
         <PDBx:U13>-0.07596</PDBx:U13>
         <PDBx:U22>0.44831</PDBx:U22>
         <PDBx:U23>-0.01791</PDBx:U23>
         <PDBx:U33>0.33806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="999">
         <PDBx:U11>0.41585</PDBx:U11>
         <PDBx:U12>0.05464</PDBx:U12>
         <PDBx:U13>-0.07588</PDBx:U13>
         <PDBx:U22>0.52161</PDBx:U22>
         <PDBx:U23>-0.00982</PDBx:U23>
         <PDBx:U33>0.40374</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1000">
         <PDBx:U11>0.25421</PDBx:U11>
         <PDBx:U12>0.05315</PDBx:U12>
         <PDBx:U13>-0.01844</PDBx:U13>
         <PDBx:U22>0.34072</PDBx:U22>
         <PDBx:U23>0.00604</PDBx:U23>
         <PDBx:U33>0.29418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1001">
         <PDBx:U11>0.20969</PDBx:U11>
         <PDBx:U12>0.05497</PDBx:U12>
         <PDBx:U13>-0.00756</PDBx:U13>
         <PDBx:U22>0.28652</PDBx:U22>
         <PDBx:U23>0.00756</PDBx:U23>
         <PDBx:U33>0.25024</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1002">
         <PDBx:U11>0.12876</PDBx:U11>
         <PDBx:U12>0.06396</PDBx:U12>
         <PDBx:U13>-0.00279</PDBx:U13>
         <PDBx:U22>0.22325</PDBx:U22>
         <PDBx:U23>0.01510</PDBx:U23>
         <PDBx:U33>0.18868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1003">
         <PDBx:U11>0.20231</PDBx:U11>
         <PDBx:U12>0.06955</PDBx:U12>
         <PDBx:U13>0.00106</PDBx:U13>
         <PDBx:U22>0.29070</PDBx:U22>
         <PDBx:U23>0.01667</PDBx:U23>
         <PDBx:U33>0.25710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1004">
         <PDBx:U11>0.21648</PDBx:U11>
         <PDBx:U12>0.04397</PDBx:U12>
         <PDBx:U13>0.00244</PDBx:U13>
         <PDBx:U22>0.28384</PDBx:U22>
         <PDBx:U23>0.00521</PDBx:U23>
         <PDBx:U33>0.26181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1005">
         <PDBx:U11>0.22085</PDBx:U11>
         <PDBx:U12>0.03445</PDBx:U12>
         <PDBx:U13>-0.00168</PDBx:U13>
         <PDBx:U22>0.26474</PDBx:U22>
         <PDBx:U23>-0.00124</PDBx:U23>
         <PDBx:U33>0.24218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1006">
         <PDBx:U11>0.20404</PDBx:U11>
         <PDBx:U12>0.04585</PDBx:U12>
         <PDBx:U13>0.01390</PDBx:U13>
         <PDBx:U22>0.26239</PDBx:U22>
         <PDBx:U23>0.00652</PDBx:U23>
         <PDBx:U33>0.24997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1007">
         <PDBx:U11>0.25656</PDBx:U11>
         <PDBx:U12>0.02160</PDBx:U12>
         <PDBx:U13>0.00970</PDBx:U13>
         <PDBx:U22>0.28998</PDBx:U22>
         <PDBx:U23>-0.00320</PDBx:U23>
         <PDBx:U33>0.27979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1008">
         <PDBx:U11>0.14270</PDBx:U11>
         <PDBx:U12>0.06511</PDBx:U12>
         <PDBx:U13>-0.00339</PDBx:U13>
         <PDBx:U22>0.25857</PDBx:U22>
         <PDBx:U23>0.02011</PDBx:U23>
         <PDBx:U33>0.22576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1009">
         <PDBx:U11>0.18025</PDBx:U11>
         <PDBx:U12>0.07390</PDBx:U12>
         <PDBx:U13>0.00062</PDBx:U13>
         <PDBx:U22>0.31030</PDBx:U22>
         <PDBx:U23>0.02830</PDBx:U23>
         <PDBx:U33>0.28148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1010">
         <PDBx:U11>0.20994</PDBx:U11>
         <PDBx:U12>0.08011</PDBx:U12>
         <PDBx:U13>-0.00515</PDBx:U13>
         <PDBx:U22>0.33718</PDBx:U22>
         <PDBx:U23>0.03060</PDBx:U23>
         <PDBx:U33>0.29541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1011">
         <PDBx:U11>0.17637</PDBx:U11>
         <PDBx:U12>0.07982</PDBx:U12>
         <PDBx:U13>0.00061</PDBx:U13>
         <PDBx:U22>0.29290</PDBx:U22>
         <PDBx:U23>0.03191</PDBx:U23>
         <PDBx:U33>0.25830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1012">
         <PDBx:U11>0.12981</PDBx:U11>
         <PDBx:U12>0.07472</PDBx:U12>
         <PDBx:U13>-0.00236</PDBx:U13>
         <PDBx:U22>0.28303</PDBx:U22>
         <PDBx:U23>0.03350</PDBx:U23>
         <PDBx:U33>0.25744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1013">
         <PDBx:U11>0.15002</PDBx:U11>
         <PDBx:U12>0.07646</PDBx:U12>
         <PDBx:U13>0.00163</PDBx:U13>
         <PDBx:U22>0.30040</PDBx:U22>
         <PDBx:U23>0.03764</PDBx:U23>
         <PDBx:U33>0.28771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1014">
         <PDBx:U11>0.13798</PDBx:U11>
         <PDBx:U12>0.07654</PDBx:U12>
         <PDBx:U13>-0.00390</PDBx:U13>
         <PDBx:U22>0.30510</PDBx:U22>
         <PDBx:U23>0.04067</PDBx:U23>
         <PDBx:U33>0.29636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1015">
         <PDBx:U11>0.13969</PDBx:U11>
         <PDBx:U12>0.07247</PDBx:U12>
         <PDBx:U13>0.00248</PDBx:U13>
         <PDBx:U22>0.31899</PDBx:U22>
         <PDBx:U23>0.03825</PDBx:U23>
         <PDBx:U33>0.32231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1016">
         <PDBx:U11>0.23126</PDBx:U11>
         <PDBx:U12>0.06795</PDBx:U12>
         <PDBx:U13>-0.00294</PDBx:U13>
         <PDBx:U22>0.42830</PDBx:U22>
         <PDBx:U23>0.03731</PDBx:U23>
         <PDBx:U33>0.42581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1017">
         <PDBx:U11>0.17473</PDBx:U11>
         <PDBx:U12>0.06749</PDBx:U12>
         <PDBx:U13>-0.01674</PDBx:U13>
         <PDBx:U22>0.37695</PDBx:U22>
         <PDBx:U23>0.03729</PDBx:U23>
         <PDBx:U33>0.35451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1018">
         <PDBx:U11>0.18537</PDBx:U11>
         <PDBx:U12>0.06188</PDBx:U12>
         <PDBx:U13>0.00577</PDBx:U13>
         <PDBx:U22>0.39327</PDBx:U22>
         <PDBx:U23>0.03511</PDBx:U23>
         <PDBx:U33>0.40454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1019">
         <PDBx:U11>0.16107</PDBx:U11>
         <PDBx:U12>0.08158</PDBx:U12>
         <PDBx:U13>-0.01603</PDBx:U13>
         <PDBx:U22>0.29322</PDBx:U22>
         <PDBx:U23>0.02914</PDBx:U23>
         <PDBx:U33>0.23387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1020">
         <PDBx:U11>0.17576</PDBx:U11>
         <PDBx:U12>0.08161</PDBx:U12>
         <PDBx:U13>-0.01602</PDBx:U13>
         <PDBx:U22>0.30772</PDBx:U22>
         <PDBx:U23>0.02899</PDBx:U23>
         <PDBx:U33>0.24830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1021">
         <PDBx:U11>0.20805</PDBx:U11>
         <PDBx:U12>0.08340</PDBx:U12>
         <PDBx:U13>-0.01861</PDBx:U13>
         <PDBx:U22>0.33342</PDBx:U22>
         <PDBx:U23>0.02931</PDBx:U23>
         <PDBx:U33>0.26314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1022">
         <PDBx:U11>0.20034</PDBx:U11>
         <PDBx:U12>0.08341</PDBx:U12>
         <PDBx:U13>-0.01887</PDBx:U13>
         <PDBx:U22>0.32598</PDBx:U22>
         <PDBx:U23>0.02924</PDBx:U23>
         <PDBx:U33>0.25540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1023">
         <PDBx:U11>0.17789</PDBx:U11>
         <PDBx:U12>0.08449</PDBx:U12>
         <PDBx:U13>-0.01418</PDBx:U13>
         <PDBx:U22>0.28811</PDBx:U22>
         <PDBx:U23>0.02502</PDBx:U23>
         <PDBx:U33>0.21865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1024">
         <PDBx:U11>0.19020</PDBx:U11>
         <PDBx:U12>0.08460</PDBx:U12>
         <PDBx:U13>-0.01469</PDBx:U13>
         <PDBx:U22>0.30065</PDBx:U22>
         <PDBx:U23>0.02487</PDBx:U23>
         <PDBx:U33>0.23023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1025">
         <PDBx:U11>0.19655</PDBx:U11>
         <PDBx:U12>0.08457</PDBx:U12>
         <PDBx:U13>-0.01029</PDBx:U13>
         <PDBx:U22>0.30276</PDBx:U22>
         <PDBx:U23>0.02692</PDBx:U23>
         <PDBx:U33>0.23298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1026">
         <PDBx:U11>0.18645</PDBx:U11>
         <PDBx:U12>0.08483</PDBx:U12>
         <PDBx:U13>-0.01107</PDBx:U13>
         <PDBx:U22>0.29315</PDBx:U22>
         <PDBx:U23>0.02669</PDBx:U23>
         <PDBx:U33>0.22160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1027">
         <PDBx:U11>0.18545</PDBx:U11>
         <PDBx:U12>0.08466</PDBx:U12>
         <PDBx:U13>-0.02980</PDBx:U13>
         <PDBx:U22>0.31663</PDBx:U22>
         <PDBx:U23>0.02644</PDBx:U23>
         <PDBx:U33>0.22692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1028">
         <PDBx:U11>0.20717</PDBx:U11>
         <PDBx:U12>0.08448</PDBx:U12>
         <PDBx:U13>-0.03029</PDBx:U13>
         <PDBx:U22>0.33951</PDBx:U22>
         <PDBx:U23>0.02664</PDBx:U23>
         <PDBx:U33>0.24980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1029">
         <PDBx:U11>0.24413</PDBx:U11>
         <PDBx:U12>0.08318</PDBx:U12>
         <PDBx:U13>-0.03636</PDBx:U13>
         <PDBx:U22>0.39032</PDBx:U22>
         <PDBx:U23>0.03131</PDBx:U23>
         <PDBx:U33>0.29712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1030">
         <PDBx:U11>0.24817</PDBx:U11>
         <PDBx:U12>0.08258</PDBx:U12>
         <PDBx:U13>-0.03682</PDBx:U13>
         <PDBx:U22>0.39650</PDBx:U22>
         <PDBx:U23>0.03135</PDBx:U23>
         <PDBx:U33>0.30513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1031">
         <PDBx:U11>0.31187</PDBx:U11>
         <PDBx:U12>0.08358</PDBx:U12>
         <PDBx:U13>-0.04739</PDBx:U13>
         <PDBx:U22>0.46079</PDBx:U22>
         <PDBx:U23>0.02770</PDBx:U23>
         <PDBx:U33>0.34667</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1032">
         <PDBx:U11>0.29760</PDBx:U11>
         <PDBx:U12>0.08072</PDBx:U12>
         <PDBx:U13>-0.04982</PDBx:U13>
         <PDBx:U22>0.45305</PDBx:U22>
         <PDBx:U23>0.02621</PDBx:U23>
         <PDBx:U33>0.34545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1033">
         <PDBx:U11>0.30544</PDBx:U11>
         <PDBx:U12>0.08101</PDBx:U12>
         <PDBx:U13>-0.05635</PDBx:U13>
         <PDBx:U22>0.46939</PDBx:U22>
         <PDBx:U23>0.03208</PDBx:U23>
         <PDBx:U33>0.35192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1034">
         <PDBx:U11>0.35010</PDBx:U11>
         <PDBx:U12>0.08287</PDBx:U12>
         <PDBx:U13>-0.05523</PDBx:U13>
         <PDBx:U22>0.49909</PDBx:U22>
         <PDBx:U23>0.02297</PDBx:U23>
         <PDBx:U33>0.37265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1035">
         <PDBx:U11>0.41726</PDBx:U11>
         <PDBx:U12>0.08240</PDBx:U12>
         <PDBx:U13>-0.05101</PDBx:U13>
         <PDBx:U22>0.58553</PDBx:U22>
         <PDBx:U23>0.04093</PDBx:U23>
         <PDBx:U33>0.48144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1036">
         <PDBx:U11>0.32517</PDBx:U11>
         <PDBx:U12>0.07924</PDBx:U12>
         <PDBx:U13>-0.06872</PDBx:U13>
         <PDBx:U22>0.48141</PDBx:U22>
         <PDBx:U23>0.01953</PDBx:U23>
         <PDBx:U33>0.34049</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1037">
         <PDBx:U11>0.17525</PDBx:U11>
         <PDBx:U12>0.08585</PDBx:U12>
         <PDBx:U13>-0.01617</PDBx:U13>
         <PDBx:U22>0.27751</PDBx:U22>
         <PDBx:U23>0.01905</PDBx:U23>
         <PDBx:U33>0.20771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1038">
         <PDBx:U11>0.18765</PDBx:U11>
         <PDBx:U12>0.08728</PDBx:U12>
         <PDBx:U13>-0.01436</PDBx:U13>
         <PDBx:U22>0.27432</PDBx:U22>
         <PDBx:U23>0.01459</PDBx:U23>
         <PDBx:U33>0.20585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1039">
         <PDBx:U11>0.22693</PDBx:U11>
         <PDBx:U12>0.08472</PDBx:U12>
         <PDBx:U13>-0.00462</PDBx:U13>
         <PDBx:U22>0.30807</PDBx:U22>
         <PDBx:U23>0.01754</PDBx:U23>
         <PDBx:U33>0.25430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1040">
         <PDBx:U11>0.18210</PDBx:U11>
         <PDBx:U12>0.08394</PDBx:U12>
         <PDBx:U13>-0.00250</PDBx:U13>
         <PDBx:U22>0.25771</PDBx:U22>
         <PDBx:U23>0.01724</PDBx:U23>
         <PDBx:U33>0.20461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1041">
         <PDBx:U11>0.20749</PDBx:U11>
         <PDBx:U12>0.08298</PDBx:U12>
         <PDBx:U13>-0.01887</PDBx:U13>
         <PDBx:U22>0.27532</PDBx:U22>
         <PDBx:U23>0.00659</PDBx:U23>
         <PDBx:U33>0.20931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1042">
         <PDBx:U11>0.24590</PDBx:U11>
         <PDBx:U12>0.08304</PDBx:U12>
         <PDBx:U13>-0.02904</PDBx:U13>
         <PDBx:U22>0.31304</PDBx:U22>
         <PDBx:U23>0.00163</PDBx:U23>
         <PDBx:U33>0.23476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1043">
         <PDBx:U11>0.33459</PDBx:U11>
         <PDBx:U12>0.07268</PDBx:U12>
         <PDBx:U13>-0.03316</PDBx:U13>
         <PDBx:U22>0.37676</PDBx:U22>
         <PDBx:U23>-0.00610</PDBx:U23>
         <PDBx:U33>0.30746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1044">
         <PDBx:U11>0.22256</PDBx:U11>
         <PDBx:U12>0.07747</PDBx:U12>
         <PDBx:U13>-0.03341</PDBx:U13>
         <PDBx:U22>0.24376</PDBx:U22>
         <PDBx:U23>-0.00990</PDBx:U23>
         <PDBx:U33>0.17878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1045">
         <PDBx:U11>0.15902</PDBx:U11>
         <PDBx:U12>0.08322</PDBx:U12>
         <PDBx:U13>0.00177</PDBx:U13>
         <PDBx:U22>0.24294</PDBx:U22>
         <PDBx:U23>0.01996</PDBx:U23>
         <PDBx:U33>0.20095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1046">
         <PDBx:U11>0.12739</PDBx:U11>
         <PDBx:U12>0.08060</PDBx:U12>
         <PDBx:U13>0.01167</PDBx:U13>
         <PDBx:U22>0.20390</PDBx:U22>
         <PDBx:U23>0.02154</PDBx:U23>
         <PDBx:U33>0.17678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1047">
         <PDBx:U11>0.14000</PDBx:U11>
         <PDBx:U12>0.07834</PDBx:U12>
         <PDBx:U13>0.01290</PDBx:U13>
         <PDBx:U22>0.21961</PDBx:U22>
         <PDBx:U23>0.02594</PDBx:U23>
         <PDBx:U33>0.19514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1048">
         <PDBx:U11>0.20097</PDBx:U11>
         <PDBx:U12>0.07699</PDBx:U12>
         <PDBx:U13>0.01670</PDBx:U13>
         <PDBx:U22>0.27303</PDBx:U22>
         <PDBx:U23>0.02582</PDBx:U23>
         <PDBx:U33>0.25416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1049">
         <PDBx:U11>0.13676</PDBx:U11>
         <PDBx:U12>0.07608</PDBx:U12>
         <PDBx:U13>0.01998</PDBx:U13>
         <PDBx:U22>0.21431</PDBx:U22>
         <PDBx:U23>0.02194</PDBx:U23>
         <PDBx:U33>0.20083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1050">
         <PDBx:U11>0.13673</PDBx:U11>
         <PDBx:U12>0.07878</PDBx:U12>
         <PDBx:U13>0.00934</PDBx:U13>
         <PDBx:U22>0.22748</PDBx:U22>
         <PDBx:U23>0.03006</PDBx:U23>
         <PDBx:U33>0.19825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1051">
         <PDBx:U11>0.15929</PDBx:U11>
         <PDBx:U12>0.07861</PDBx:U12>
         <PDBx:U13>0.01078</PDBx:U13>
         <PDBx:U22>0.25220</PDBx:U22>
         <PDBx:U23>0.03520</PDBx:U23>
         <PDBx:U33>0.22388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1052">
         <PDBx:U11>0.18407</PDBx:U11>
         <PDBx:U12>0.07941</PDBx:U12>
         <PDBx:U13>0.00952</PDBx:U13>
         <PDBx:U22>0.27434</PDBx:U22>
         <PDBx:U23>0.03440</PDBx:U23>
         <PDBx:U33>0.23545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1053">
         <PDBx:U11>0.17755</PDBx:U11>
         <PDBx:U12>0.07858</PDBx:U12>
         <PDBx:U13>0.01383</PDBx:U13>
         <PDBx:U22>0.26470</PDBx:U22>
         <PDBx:U23>0.03684</PDBx:U23>
         <PDBx:U33>0.23058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1054">
         <PDBx:U11>0.16041</PDBx:U11>
         <PDBx:U12>0.08043</PDBx:U12>
         <PDBx:U13>0.00600</PDBx:U13>
         <PDBx:U22>0.26542</PDBx:U22>
         <PDBx:U23>0.04004</PDBx:U23>
         <PDBx:U33>0.23145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1055">
         <PDBx:U11>0.21726</PDBx:U11>
         <PDBx:U12>0.08166</PDBx:U12>
         <PDBx:U13>0.00834</PDBx:U13>
         <PDBx:U22>0.32412</PDBx:U22>
         <PDBx:U23>0.04698</PDBx:U23>
         <PDBx:U33>0.29310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1056">
         <PDBx:U11>0.19065</PDBx:U11>
         <PDBx:U12>0.08112</PDBx:U12>
         <PDBx:U13>0.01414</PDBx:U13>
         <PDBx:U22>0.29377</PDBx:U22>
         <PDBx:U23>0.04947</PDBx:U23>
         <PDBx:U33>0.27964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1057">
         <PDBx:U11>0.25098</PDBx:U11>
         <PDBx:U12>0.08424</PDBx:U12>
         <PDBx:U13>0.00547</PDBx:U13>
         <PDBx:U22>0.36344</PDBx:U22>
         <PDBx:U23>0.05137</PDBx:U23>
         <PDBx:U33>0.31751</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1058">
         <PDBx:U11>0.28172</PDBx:U11>
         <PDBx:U12>0.08335</PDBx:U12>
         <PDBx:U13>0.01608</PDBx:U13>
         <PDBx:U22>0.38573</PDBx:U22>
         <PDBx:U23>0.05688</PDBx:U23>
         <PDBx:U33>0.37495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1059">
         <PDBx:U11>0.38661</PDBx:U11>
         <PDBx:U12>0.08631</PDBx:U12>
         <PDBx:U13>0.00809</PDBx:U13>
         <PDBx:U22>0.50123</PDBx:U22>
         <PDBx:U23>0.05950</PDBx:U23>
         <PDBx:U33>0.45717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1060">
         <PDBx:U11>0.41848</PDBx:U11>
         <PDBx:U12>0.08590</PDBx:U12>
         <PDBx:U13>0.01296</PDBx:U13>
         <PDBx:U22>0.52826</PDBx:U22>
         <PDBx:U23>0.06248</PDBx:U23>
         <PDBx:U33>0.50265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1061">
         <PDBx:U11>0.42086</PDBx:U11>
         <PDBx:U12>0.08872</PDBx:U12>
         <PDBx:U13>0.01554</PDBx:U13>
         <PDBx:U22>0.53152</PDBx:U22>
         <PDBx:U23>0.07151</PDBx:U23>
         <PDBx:U33>0.50916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1062">
         <PDBx:U11>0.18308</PDBx:U11>
         <PDBx:U12>0.08148</PDBx:U12>
         <PDBx:U13>0.00397</PDBx:U13>
         <PDBx:U22>0.27528</PDBx:U22>
         <PDBx:U23>0.03059</PDBx:U23>
         <PDBx:U33>0.22215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1063">
         <PDBx:U11>0.18459</PDBx:U11>
         <PDBx:U12>0.08308</PDBx:U12>
         <PDBx:U13>0.00366</PDBx:U13>
         <PDBx:U22>0.27644</PDBx:U22>
         <PDBx:U23>0.02888</PDBx:U23>
         <PDBx:U33>0.21312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1064">
         <PDBx:U11>0.18871</PDBx:U11>
         <PDBx:U12>0.08134</PDBx:U12>
         <PDBx:U13>0.00603</PDBx:U13>
         <PDBx:U22>0.27097</PDBx:U22>
         <PDBx:U23>0.02511</PDBx:U23>
         <PDBx:U33>0.21640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1065">
         <PDBx:U11>0.16067</PDBx:U11>
         <PDBx:U12>0.08129</PDBx:U12>
         <PDBx:U13>0.00839</PDBx:U13>
         <PDBx:U22>0.24418</PDBx:U22>
         <PDBx:U23>0.02610</PDBx:U23>
         <PDBx:U33>0.18869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1066">
         <PDBx:U11>0.19798</PDBx:U11>
         <PDBx:U12>0.08684</PDBx:U12>
         <PDBx:U13>-0.00249</PDBx:U13>
         <PDBx:U22>0.29308</PDBx:U22>
         <PDBx:U23>0.02407</PDBx:U23>
         <PDBx:U33>0.21321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1067">
         <PDBx:U11>0.23760</PDBx:U11>
         <PDBx:U12>0.08905</PDBx:U12>
         <PDBx:U13>-0.00567</PDBx:U13>
         <PDBx:U22>0.34397</PDBx:U22>
         <PDBx:U23>0.02808</PDBx:U23>
         <PDBx:U33>0.25235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1068">
         <PDBx:U11>0.27090</PDBx:U11>
         <PDBx:U12>0.09362</PDBx:U12>
         <PDBx:U13>-0.01153</PDBx:U13>
         <PDBx:U22>0.38063</PDBx:U22>
         <PDBx:U23>0.02254</PDBx:U23>
         <PDBx:U33>0.27064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1069">
         <PDBx:U11>0.23976</PDBx:U11>
         <PDBx:U12>0.09519</PDBx:U12>
         <PDBx:U13>-0.01425</PDBx:U13>
         <PDBx:U22>0.34162</PDBx:U22>
         <PDBx:U23>0.01504</PDBx:U23>
         <PDBx:U33>0.23076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1070">
         <PDBx:U11>0.35214</PDBx:U11>
         <PDBx:U12>0.09637</PDBx:U12>
         <PDBx:U13>-0.01421</PDBx:U13>
         <PDBx:U22>0.47254</PDBx:U22>
         <PDBx:U23>0.02594</PDBx:U23>
         <PDBx:U33>0.34775</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1071">
         <PDBx:U11>0.14631</PDBx:U11>
         <PDBx:U12>0.08072</PDBx:U12>
         <PDBx:U13>0.00510</PDBx:U13>
         <PDBx:U22>0.21996</PDBx:U22>
         <PDBx:U23>0.02100</PDBx:U23>
         <PDBx:U33>0.17257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1072">
         <PDBx:U11>0.17622</PDBx:U11>
         <PDBx:U12>0.08006</PDBx:U12>
         <PDBx:U13>0.00636</PDBx:U13>
         <PDBx:U22>0.24045</PDBx:U22>
         <PDBx:U23>0.01776</PDBx:U23>
         <PDBx:U33>0.20020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1073">
         <PDBx:U11>0.19151</PDBx:U11>
         <PDBx:U12>0.07733</PDBx:U12>
         <PDBx:U13>0.01314</PDBx:U13>
         <PDBx:U22>0.25492</PDBx:U22>
         <PDBx:U23>0.02161</PDBx:U23>
         <PDBx:U33>0.22661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1074">
         <PDBx:U11>0.16053</PDBx:U11>
         <PDBx:U12>0.07701</PDBx:U12>
         <PDBx:U13>0.01403</PDBx:U13>
         <PDBx:U22>0.22286</PDBx:U22>
         <PDBx:U23>0.02102</PDBx:U23>
         <PDBx:U33>0.19659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1075">
         <PDBx:U11>0.20980</PDBx:U11>
         <PDBx:U12>0.08170</PDBx:U12>
         <PDBx:U13>0.00461</PDBx:U13>
         <PDBx:U22>0.26301</PDBx:U22>
         <PDBx:U23>0.01343</PDBx:U23>
         <PDBx:U33>0.22646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1076">
         <PDBx:U11>0.21632</PDBx:U11>
         <PDBx:U12>0.08523</PDBx:U12>
         <PDBx:U13>-0.00364</PDBx:U13>
         <PDBx:U22>0.26659</PDBx:U22>
         <PDBx:U23>0.00856</PDBx:U23>
         <PDBx:U33>0.21932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1077">
         <PDBx:U11>0.19650</PDBx:U11>
         <PDBx:U12>0.08207</PDBx:U12>
         <PDBx:U13>0.00608</PDBx:U13>
         <PDBx:U22>0.23774</PDBx:U22>
         <PDBx:U23>0.01073</PDBx:U23>
         <PDBx:U33>0.20893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1078">
         <PDBx:U11>0.21375</PDBx:U11>
         <PDBx:U12>0.08586</PDBx:U12>
         <PDBx:U13>-0.00553</PDBx:U13>
         <PDBx:U22>0.25012</PDBx:U22>
         <PDBx:U23>0.00513</PDBx:U23>
         <PDBx:U33>0.20758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1079">
         <PDBx:U11>0.14306</PDBx:U11>
         <PDBx:U12>0.07583</PDBx:U12>
         <PDBx:U13>0.01789</PDBx:U13>
         <PDBx:U22>0.20739</PDBx:U22>
         <PDBx:U23>0.02528</PDBx:U23>
         <PDBx:U33>0.18786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>273</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1080">
         <PDBx:U11>0.20970</PDBx:U11>
         <PDBx:U12>0.07396</PDBx:U12>
         <PDBx:U13>0.02459</PDBx:U13>
         <PDBx:U22>0.27104</PDBx:U22>
         <PDBx:U23>0.02848</PDBx:U23>
         <PDBx:U33>0.26388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>273</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1081">
         <PDBx:U11>0.13646</PDBx:U11>
         <PDBx:U12>0.07434</PDBx:U12>
         <PDBx:U13>0.02493</PDBx:U13>
         <PDBx:U22>0.20430</PDBx:U22>
         <PDBx:U23>0.03330</PDBx:U23>
         <PDBx:U33>0.19292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>273</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1082">
         <PDBx:U11>0.16748</PDBx:U11>
         <PDBx:U12>0.07352</PDBx:U12>
         <PDBx:U13>0.02887</PDBx:U13>
         <PDBx:U22>0.23228</PDBx:U22>
         <PDBx:U23>0.03447</PDBx:U23>
         <PDBx:U33>0.22802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>273</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1083">
         <PDBx:U11>0.16166</PDBx:U11>
         <PDBx:U12>0.07312</PDBx:U12>
         <PDBx:U13>0.02942</PDBx:U13>
         <PDBx:U22>0.22307</PDBx:U22>
         <PDBx:U23>0.03117</PDBx:U23>
         <PDBx:U33>0.22651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>273</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1084">
         <PDBx:U11>0.26224</PDBx:U11>
         <PDBx:U12>0.07231</PDBx:U12>
         <PDBx:U13>0.03476</PDBx:U13>
         <PDBx:U22>0.31421</PDBx:U22>
         <PDBx:U23>0.02569</PDBx:U23>
         <PDBx:U33>0.32638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>273</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1085">
         <PDBx:U11>0.12705</PDBx:U11>
         <PDBx:U12>0.07616</PDBx:U12>
         <PDBx:U13>0.02191</PDBx:U13>
         <PDBx:U22>0.20399</PDBx:U22>
         <PDBx:U23>0.03684</PDBx:U23>
         <PDBx:U33>0.18109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1086">
         <PDBx:U11>0.13808</PDBx:U11>
         <PDBx:U12>0.07769</PDBx:U12>
         <PDBx:U13>0.02397</PDBx:U13>
         <PDBx:U22>0.22198</PDBx:U22>
         <PDBx:U23>0.04292</PDBx:U23>
         <PDBx:U33>0.19286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1087">
         <PDBx:U11>0.17276</PDBx:U11>
         <PDBx:U12>0.07798</PDBx:U12>
         <PDBx:U13>0.02323</PDBx:U13>
         <PDBx:U22>0.25872</PDBx:U22>
         <PDBx:U23>0.03946</PDBx:U23>
         <PDBx:U33>0.22341</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1088">
         <PDBx:U11>0.18765</PDBx:U11>
         <PDBx:U12>0.07792</PDBx:U12>
         <PDBx:U13>0.02750</PDBx:U13>
         <PDBx:U22>0.27651</PDBx:U22>
         <PDBx:U23>0.04335</PDBx:U23>
         <PDBx:U33>0.24392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1089">
         <PDBx:U11>0.20807</PDBx:U11>
         <PDBx:U12>0.08091</PDBx:U12>
         <PDBx:U13>0.02106</PDBx:U13>
         <PDBx:U22>0.30205</PDBx:U22>
         <PDBx:U23>0.04735</PDBx:U23>
         <PDBx:U33>0.25817</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1090">
         <PDBx:U11>0.35182</PDBx:U11>
         <PDBx:U12>0.08177</PDBx:U12>
         <PDBx:U13>0.02158</PDBx:U13>
         <PDBx:U22>0.44780</PDBx:U22>
         <PDBx:U23>0.05352</PDBx:U23>
         <PDBx:U33>0.41001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1091">
         <PDBx:U11>0.47578</PDBx:U11>
         <PDBx:U12>0.08556</PDBx:U12>
         <PDBx:U13>0.02330</PDBx:U13>
         <PDBx:U22>0.58076</PDBx:U22>
         <PDBx:U23>0.06368</PDBx:U23>
         <PDBx:U33>0.53347</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1092">
         <PDBx:U11>0.67179</PDBx:U11>
         <PDBx:U12>0.08871</PDBx:U12>
         <PDBx:U13>0.02111</PDBx:U13>
         <PDBx:U22>0.78646</PDBx:U22>
         <PDBx:U23>0.06302</PDBx:U23>
         <PDBx:U33>0.71647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1093">
         <PDBx:U11>0.78988</PDBx:U11>
         <PDBx:U12>0.09339</PDBx:U12>
         <PDBx:U13>0.02437</PDBx:U13>
         <PDBx:U22>0.91541</PDBx:U22>
         <PDBx:U23>0.07388</PDBx:U23>
         <PDBx:U33>0.83179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1094">
         <PDBx:U11>0.13872</PDBx:U11>
         <PDBx:U12>0.07880</PDBx:U12>
         <PDBx:U13>0.01795</PDBx:U13>
         <PDBx:U22>0.22395</PDBx:U22>
         <PDBx:U23>0.03255</PDBx:U23>
         <PDBx:U33>0.18106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1095">
         <PDBx:U11>0.14424</PDBx:U11>
         <PDBx:U12>0.07876</PDBx:U12>
         <PDBx:U13>0.01793</PDBx:U13>
         <PDBx:U22>0.22930</PDBx:U22>
         <PDBx:U23>0.03248</PDBx:U23>
         <PDBx:U33>0.18660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1096">
         <PDBx:U11>0.14594</PDBx:U11>
         <PDBx:U12>0.07984</PDBx:U12>
         <PDBx:U13>0.01634</PDBx:U13>
         <PDBx:U22>0.23396</PDBx:U22>
         <PDBx:U23>0.02839</PDBx:U23>
         <PDBx:U33>0.18651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1097">
         <PDBx:U11>0.16333</PDBx:U11>
         <PDBx:U12>0.07988</PDBx:U12>
         <PDBx:U13>0.01611</PDBx:U13>
         <PDBx:U22>0.25117</PDBx:U22>
         <PDBx:U23>0.02817</PDBx:U23>
         <PDBx:U33>0.20350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1098">
         <PDBx:U11>0.19312</PDBx:U11>
         <PDBx:U12>0.07780</PDBx:U12>
         <PDBx:U13>0.01792</PDBx:U13>
         <PDBx:U22>0.27556</PDBx:U22>
         <PDBx:U23>0.02624</PDBx:U23>
         <PDBx:U33>0.24124</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1099">
         <PDBx:U11>0.17561</PDBx:U11>
         <PDBx:U12>0.07789</PDBx:U12>
         <PDBx:U13>0.01766</PDBx:U13>
         <PDBx:U22>0.25806</PDBx:U22>
         <PDBx:U23>0.02601</PDBx:U23>
         <PDBx:U33>0.22332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1100">
         <PDBx:U11>0.16438</PDBx:U11>
         <PDBx:U12>0.07784</PDBx:U12>
         <PDBx:U13>0.02019</PDBx:U13>
         <PDBx:U22>0.25315</PDBx:U22>
         <PDBx:U23>0.02726</PDBx:U23>
         <PDBx:U33>0.21978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1101">
         <PDBx:U11>0.16823</PDBx:U11>
         <PDBx:U12>0.07800</PDBx:U12>
         <PDBx:U13>0.01981</PDBx:U13>
         <PDBx:U22>0.25723</PDBx:U22>
         <PDBx:U23>0.02695</PDBx:U23>
         <PDBx:U33>0.22302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1102">
         <PDBx:U11>0.21996</PDBx:U11>
         <PDBx:U12>0.08212</PDBx:U12>
         <PDBx:U13>0.00996</PDBx:U13>
         <PDBx:U22>0.30580</PDBx:U22>
         <PDBx:U23>0.02147</PDBx:U23>
         <PDBx:U33>0.24985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1103">
         <PDBx:U11>0.20399</PDBx:U11>
         <PDBx:U12>0.08214</PDBx:U12>
         <PDBx:U13>0.00969</PDBx:U13>
         <PDBx:U22>0.28937</PDBx:U22>
         <PDBx:U23>0.02132</PDBx:U23>
         <PDBx:U33>0.23329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1104">
         <PDBx:U11>0.21433</PDBx:U11>
         <PDBx:U12>0.08381</PDBx:U12>
         <PDBx:U13>0.00827</PDBx:U13>
         <PDBx:U22>0.30371</PDBx:U22>
         <PDBx:U23>0.01753</PDBx:U23>
         <PDBx:U33>0.24505</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1105">
         <PDBx:U11>0.27143</PDBx:U11>
         <PDBx:U12>0.08490</PDBx:U12>
         <PDBx:U13>0.00824</PDBx:U13>
         <PDBx:U22>0.36268</PDBx:U22>
         <PDBx:U23>0.02262</PDBx:U23>
         <PDBx:U33>0.29325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1106">
         <PDBx:U11>0.17708</PDBx:U11>
         <PDBx:U12>0.07678</PDBx:U12>
         <PDBx:U13>0.01698</PDBx:U13>
         <PDBx:U22>0.24885</PDBx:U22>
         <PDBx:U23>0.02311</PDBx:U23>
         <PDBx:U33>0.22348</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1107">
         <PDBx:U11>0.15390</PDBx:U11>
         <PDBx:U12>0.07644</PDBx:U12>
         <PDBx:U13>0.01868</PDBx:U13>
         <PDBx:U22>0.22001</PDBx:U22>
         <PDBx:U23>0.02113</PDBx:U23>
         <PDBx:U33>0.20516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1108">
         <PDBx:U11>0.17130</PDBx:U11>
         <PDBx:U12>0.07445</PDBx:U12>
         <PDBx:U13>0.02678</PDBx:U13>
         <PDBx:U22>0.23768</PDBx:U22>
         <PDBx:U23>0.02681</PDBx:U23>
         <PDBx:U33>0.23390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1109">
         <PDBx:U11>0.17343</PDBx:U11>
         <PDBx:U12>0.07440</PDBx:U12>
         <PDBx:U13>0.02919</PDBx:U13>
         <PDBx:U22>0.24060</PDBx:U22>
         <PDBx:U23>0.02668</PDBx:U23>
         <PDBx:U33>0.24364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1110">
         <PDBx:U11>0.15228</PDBx:U11>
         <PDBx:U12>0.07748</PDBx:U12>
         <PDBx:U13>0.01718</PDBx:U13>
         <PDBx:U22>0.20518</PDBx:U22>
         <PDBx:U23>0.01702</PDBx:U23>
         <PDBx:U33>0.19497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1111">
         <PDBx:U11>0.14084</PDBx:U11>
         <PDBx:U12>0.07897</PDBx:U12>
         <PDBx:U13>0.01945</PDBx:U13>
         <PDBx:U22>0.18483</PDBx:U22>
         <PDBx:U23>0.01487</PDBx:U23>
         <PDBx:U33>0.18434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1112">
         <PDBx:U11>0.16943</PDBx:U11>
         <PDBx:U12>0.08014</PDBx:U12>
         <PDBx:U13>0.00842</PDBx:U13>
         <PDBx:U22>0.22049</PDBx:U22>
         <PDBx:U23>0.01208</PDBx:U23>
         <PDBx:U33>0.19948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1113">
         <PDBx:U11>0.14254</PDBx:U11>
         <PDBx:U12>0.07337</PDBx:U12>
         <PDBx:U13>0.03088</PDBx:U13>
         <PDBx:U22>0.20857</PDBx:U22>
         <PDBx:U23>0.03239</PDBx:U23>
         <PDBx:U33>0.20762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1114">
         <PDBx:U11>0.20464</PDBx:U11>
         <PDBx:U12>0.07230</PDBx:U12>
         <PDBx:U13>0.03855</PDBx:U13>
         <PDBx:U22>0.26920</PDBx:U22>
         <PDBx:U23>0.03909</PDBx:U23>
         <PDBx:U33>0.28016</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1115">
         <PDBx:U11>0.20829</PDBx:U11>
         <PDBx:U12>0.07283</PDBx:U12>
         <PDBx:U13>0.04007</PDBx:U13>
         <PDBx:U22>0.28407</PDBx:U22>
         <PDBx:U23>0.04355</PDBx:U23>
         <PDBx:U33>0.28953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1116">
         <PDBx:U11>0.19841</PDBx:U11>
         <PDBx:U12>0.07156</PDBx:U12>
         <PDBx:U13>0.04628</PDBx:U13>
         <PDBx:U22>0.27317</PDBx:U22>
         <PDBx:U23>0.04725</PDBx:U23>
         <PDBx:U33>0.29052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1117">
         <PDBx:U11>0.15166</PDBx:U11>
         <PDBx:U12>0.07263</PDBx:U12>
         <PDBx:U13>0.04122</PDBx:U13>
         <PDBx:U22>0.21450</PDBx:U22>
         <PDBx:U23>0.04503</PDBx:U23>
         <PDBx:U33>0.22928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1118">
         <PDBx:U11>0.22645</PDBx:U11>
         <PDBx:U12>0.07241</PDBx:U12>
         <PDBx:U13>0.04959</PDBx:U13>
         <PDBx:U22>0.28356</PDBx:U22>
         <PDBx:U23>0.05244</PDBx:U23>
         <PDBx:U33>0.31529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1119">
         <PDBx:U11>0.22759</PDBx:U11>
         <PDBx:U12>0.07074</PDBx:U12>
         <PDBx:U13>0.05515</PDBx:U13>
         <PDBx:U22>0.27422</PDBx:U22>
         <PDBx:U23>0.05023</PDBx:U23>
         <PDBx:U33>0.32190</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1120">
         <PDBx:U11>0.25258</PDBx:U11>
         <PDBx:U12>0.07469</PDBx:U12>
         <PDBx:U13>0.05114</PDBx:U13>
         <PDBx:U22>0.31527</PDBx:U22>
         <PDBx:U23>0.06181</PDBx:U23>
         <PDBx:U33>0.34475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1121">
         <PDBx:U11>0.23299</PDBx:U11>
         <PDBx:U12>0.07462</PDBx:U12>
         <PDBx:U13>0.03582</PDBx:U13>
         <PDBx:U22>0.31948</PDBx:U22>
         <PDBx:U23>0.04334</PDBx:U23>
         <PDBx:U33>0.30811</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1122">
         <PDBx:U11>0.22893</PDBx:U11>
         <PDBx:U12>0.07528</PDBx:U12>
         <PDBx:U13>0.03832</PDBx:U13>
         <PDBx:U22>0.32830</PDBx:U22>
         <PDBx:U23>0.04659</PDBx:U23>
         <PDBx:U33>0.30959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1123">
         <PDBx:U11>0.19623</PDBx:U11>
         <PDBx:U12>0.07388</PDBx:U12>
         <PDBx:U13>0.03728</PDBx:U13>
         <PDBx:U22>0.29935</PDBx:U22>
         <PDBx:U23>0.04064</PDBx:U23>
         <PDBx:U33>0.28558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1124">
         <PDBx:U11>0.20624</PDBx:U11>
         <PDBx:U12>0.07203</PDBx:U12>
         <PDBx:U13>0.04283</PDBx:U13>
         <PDBx:U22>0.31740</PDBx:U22>
         <PDBx:U23>0.04462</PDBx:U23>
         <PDBx:U33>0.30855</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1125">
         <PDBx:U11>0.21658</PDBx:U11>
         <PDBx:U12>0.07839</PDBx:U12>
         <PDBx:U13>0.03468</PDBx:U13>
         <PDBx:U22>0.32544</PDBx:U22>
         <PDBx:U23>0.04584</PDBx:U23>
         <PDBx:U33>0.28714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1126">
         <PDBx:U11>0.15343</PDBx:U11>
         <PDBx:U12>0.07948</PDBx:U12>
         <PDBx:U13>0.03667</PDBx:U13>
         <PDBx:U22>0.27681</PDBx:U22>
         <PDBx:U23>0.04547</PDBx:U23>
         <PDBx:U33>0.22860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1127">
         <PDBx:U11>0.21416</PDBx:U11>
         <PDBx:U12>0.07913</PDBx:U12>
         <PDBx:U13>0.04481</PDBx:U13>
         <PDBx:U22>0.34733</PDBx:U22>
         <PDBx:U23>0.05481</PDBx:U23>
         <PDBx:U33>0.29764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1128">
         <PDBx:U11>0.20861</PDBx:U11>
         <PDBx:U12>0.08105</PDBx:U12>
         <PDBx:U13>0.03121</PDBx:U13>
         <PDBx:U22>0.33600</PDBx:U22>
         <PDBx:U23>0.03652</PDBx:U23>
         <PDBx:U33>0.28067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1129">
         <PDBx:U11>0.22437</PDBx:U11>
         <PDBx:U12>0.07927</PDBx:U12>
         <PDBx:U13>0.04801</PDBx:U13>
         <PDBx:U22>0.37302</PDBx:U22>
         <PDBx:U23>0.05390</PDBx:U23>
         <PDBx:U33>0.31352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1130">
         <PDBx:U11>0.33324</PDBx:U11>
         <PDBx:U12>0.08223</PDBx:U12>
         <PDBx:U13>0.03376</PDBx:U13>
         <PDBx:U22>0.47546</PDBx:U22>
         <PDBx:U23>0.03518</PDBx:U23>
         <PDBx:U33>0.41205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1131">
         <PDBx:U11>0.21496</PDBx:U11>
         <PDBx:U12>0.08089</PDBx:U12>
         <PDBx:U13>0.04240</PDBx:U13>
         <PDBx:U22>0.36857</PDBx:U22>
         <PDBx:U23>0.04331</PDBx:U23>
         <PDBx:U33>0.30240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1132">
         <PDBx:U11>0.17269</PDBx:U11>
         <PDBx:U12>0.07484</PDBx:U12>
         <PDBx:U13>0.03021</PDBx:U13>
         <PDBx:U22>0.27102</PDBx:U22>
         <PDBx:U23>0.03198</PDBx:U23>
         <PDBx:U33>0.25663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1133">
         <PDBx:U11>0.16912</PDBx:U11>
         <PDBx:U12>0.07496</PDBx:U12>
         <PDBx:U13>0.02777</PDBx:U13>
         <PDBx:U22>0.27139</PDBx:U22>
         <PDBx:U23>0.02727</PDBx:U23>
         <PDBx:U33>0.26230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1134">
         <PDBx:U11>0.19873</PDBx:U11>
         <PDBx:U12>0.07252</PDBx:U12>
         <PDBx:U13>0.03493</PDBx:U13>
         <PDBx:U22>0.29443</PDBx:U22>
         <PDBx:U23>0.03112</PDBx:U23>
         <PDBx:U33>0.30321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1135">
         <PDBx:U11>0.22918</PDBx:U11>
         <PDBx:U12>0.06760</PDBx:U12>
         <PDBx:U13>0.03652</PDBx:U13>
         <PDBx:U22>0.33028</PDBx:U22>
         <PDBx:U23>0.03116</PDBx:U23>
         <PDBx:U33>0.34574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1136">
         <PDBx:U11>0.14892</PDBx:U11>
         <PDBx:U12>0.07800</PDBx:U12>
         <PDBx:U13>0.01829</PDBx:U13>
         <PDBx:U22>0.24357</PDBx:U22>
         <PDBx:U23>0.01931</PDBx:U23>
         <PDBx:U33>0.23146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1137">
         <PDBx:U11>0.21506</PDBx:U11>
         <PDBx:U12>0.07985</PDBx:U12>
         <PDBx:U13>0.01250</PDBx:U13>
         <PDBx:U22>0.30992</PDBx:U22>
         <PDBx:U23>0.01585</PDBx:U23>
         <PDBx:U33>0.28583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1138">
         <PDBx:U11>0.26689</PDBx:U11>
         <PDBx:U12>0.08235</PDBx:U12>
         <PDBx:U13>0.00413</PDBx:U13>
         <PDBx:U22>0.34921</PDBx:U22>
         <PDBx:U23>0.00993</PDBx:U23>
         <PDBx:U33>0.32526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1139">
         <PDBx:U11>0.24060</PDBx:U11>
         <PDBx:U12>0.08120</PDBx:U12>
         <PDBx:U13>0.01164</PDBx:U13>
         <PDBx:U22>0.35081</PDBx:U22>
         <PDBx:U23>0.01423</PDBx:U23>
         <PDBx:U33>0.31950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1140">
         <PDBx:U11>0.15466</PDBx:U11>
         <PDBx:U12>0.07203</PDBx:U12>
         <PDBx:U13>0.03872</PDBx:U13>
         <PDBx:U22>0.23395</PDBx:U22>
         <PDBx:U23>0.03249</PDBx:U23>
         <PDBx:U33>0.25298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1141">
         <PDBx:U11>0.17907</PDBx:U11>
         <PDBx:U12>0.06475</PDBx:U12>
         <PDBx:U13>0.04447</PDBx:U13>
         <PDBx:U22>0.24162</PDBx:U22>
         <PDBx:U23>0.03233</PDBx:U23>
         <PDBx:U33>0.28053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>282</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.01311</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.01691</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01943</PDBx:U23>
         <PDBx:U33>0.26493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.02029</PDBx:U23>
         <PDBx:U33>0.33208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02137</PDBx:U23>
         <PDBx:U33>0.31104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.01986</PDBx:U23>
         <PDBx:U33>0.24822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01646</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.01780</PDBx:U23>
         <PDBx:U33>0.24785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1207">
         <PDBx:U11>0.29238</PDBx:U11>
         <PDBx:U12>0.08483</PDBx:U12>
         <PDBx:U13>-0.05313</PDBx:U13>
         <PDBx:U22>0.24603</PDBx:U22>
         <PDBx:U23>-0.01599</PDBx:U23>
         <PDBx:U33>0.22621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1208">
         <PDBx:U11>0.32131</PDBx:U11>
         <PDBx:U12>0.09262</PDBx:U12>
         <PDBx:U13>-0.05929</PDBx:U13>
         <PDBx:U22>0.27572</PDBx:U22>
         <PDBx:U23>-0.01729</PDBx:U23>
         <PDBx:U33>0.25263</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1209">
         <PDBx:U11>0.34728</PDBx:U11>
         <PDBx:U12>0.09231</PDBx:U12>
         <PDBx:U13>-0.07675</PDBx:U13>
         <PDBx:U22>0.30451</PDBx:U22>
         <PDBx:U23>-0.02034</PDBx:U23>
         <PDBx:U33>0.28595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1210">
         <PDBx:U11>0.45481</PDBx:U11>
         <PDBx:U12>0.09259</PDBx:U12>
         <PDBx:U13>-0.08540</PDBx:U13>
         <PDBx:U22>0.38924</PDBx:U22>
         <PDBx:U23>-0.02233</PDBx:U23>
         <PDBx:U33>0.37166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1211">
         <PDBx:U11>0.49588</PDBx:U11>
         <PDBx:U12>0.08760</PDBx:U12>
         <PDBx:U13>-0.08727</PDBx:U13>
         <PDBx:U22>0.40274</PDBx:U22>
         <PDBx:U23>-0.02091</PDBx:U23>
         <PDBx:U33>0.38533</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1212">
         <PDBx:U11>0.52611</PDBx:U11>
         <PDBx:U12>0.09688</PDBx:U12>
         <PDBx:U13>-0.08860</PDBx:U13>
         <PDBx:U22>0.46952</PDBx:U22>
         <PDBx:U23>-0.02517</PDBx:U23>
         <PDBx:U33>0.45306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1213">
         <PDBx:U11>0.29019</PDBx:U11>
         <PDBx:U12>0.07871</PDBx:U12>
         <PDBx:U13>-0.03934</PDBx:U13>
         <PDBx:U22>0.24676</PDBx:U22>
         <PDBx:U23>-0.01329</PDBx:U23>
         <PDBx:U33>0.22895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1214">
         <PDBx:U11>0.28632</PDBx:U11>
         <PDBx:U12>0.08047</PDBx:U12>
         <PDBx:U13>-0.03263</PDBx:U13>
         <PDBx:U22>0.24855</PDBx:U22>
         <PDBx:U23>-0.01140</PDBx:U23>
         <PDBx:U33>0.22800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1215">
         <PDBx:U11>0.31364</PDBx:U11>
         <PDBx:U12>0.07529</PDBx:U12>
         <PDBx:U13>-0.03530</PDBx:U13>
         <PDBx:U22>0.25093</PDBx:U22>
         <PDBx:U23>-0.01285</PDBx:U23>
         <PDBx:U33>0.23112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1216">
         <PDBx:U11>0.34242</PDBx:U11>
         <PDBx:U12>0.06616</PDBx:U12>
         <PDBx:U13>-0.03277</PDBx:U13>
         <PDBx:U22>0.25942</PDBx:U22>
         <PDBx:U23>-0.01341</PDBx:U23>
         <PDBx:U33>0.24328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1217">
         <PDBx:U11>0.30369</PDBx:U11>
         <PDBx:U12>0.07656</PDBx:U12>
         <PDBx:U13>-0.01833</PDBx:U13>
         <PDBx:U22>0.27789</PDBx:U22>
         <PDBx:U23>-0.00752</PDBx:U23>
         <PDBx:U33>0.26086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1218">
         <PDBx:U11>0.24531</PDBx:U11>
         <PDBx:U12>0.08094</PDBx:U12>
         <PDBx:U13>-0.01485</PDBx:U13>
         <PDBx:U22>0.24276</PDBx:U22>
         <PDBx:U23>-0.00478</PDBx:U23>
         <PDBx:U33>0.22540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1219">
         <PDBx:U11>0.18237</PDBx:U11>
         <PDBx:U12>0.07614</PDBx:U12>
         <PDBx:U13>-0.00159</PDBx:U13>
         <PDBx:U22>0.18436</PDBx:U22>
         <PDBx:U23>-0.00061</PDBx:U23>
         <PDBx:U33>0.17485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1220">
         <PDBx:U11>0.20928</PDBx:U11>
         <PDBx:U12>0.08953</PDBx:U12>
         <PDBx:U13>-0.01708</PDBx:U13>
         <PDBx:U22>0.22727</PDBx:U22>
         <PDBx:U23>-0.00359</PDBx:U23>
         <PDBx:U33>0.20021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1221">
         <PDBx:U11>0.28644</PDBx:U11>
         <PDBx:U12>0.08040</PDBx:U12>
         <PDBx:U13>-0.03984</PDBx:U13>
         <PDBx:U22>0.22415</PDBx:U22>
         <PDBx:U23>-0.01373</PDBx:U23>
         <PDBx:U33>0.20062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1222">
         <PDBx:U11>0.29613</PDBx:U11>
         <PDBx:U12>0.07529</PDBx:U12>
         <PDBx:U13>-0.04290</PDBx:U13>
         <PDBx:U22>0.21024</PDBx:U22>
         <PDBx:U23>-0.01490</PDBx:U23>
         <PDBx:U33>0.18816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1223">
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.33358</PDBx:U11>
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         <PDBx:U23>-0.02116</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02717</PDBx:U23>
         <PDBx:U33>0.35698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.01648</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1234">
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         <PDBx:U33>0.23502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.33599</PDBx:U11>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.38134</PDBx:U11>
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         <PDBx:U13>-0.06234</PDBx:U13>
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         <PDBx:U23>-0.02584</PDBx:U23>
         <PDBx:U33>0.32040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.30774</PDBx:U11>
         <PDBx:U12>0.10635</PDBx:U12>
         <PDBx:U13>-0.06717</PDBx:U13>
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         <PDBx:U23>-0.02998</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.31296</PDBx:U11>
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         <PDBx:U13>-0.06653</PDBx:U13>
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         <PDBx:U23>-0.02440</PDBx:U23>
         <PDBx:U33>0.25072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1263">
         <PDBx:U11>0.25336</PDBx:U11>
         <PDBx:U12>0.10001</PDBx:U12>
         <PDBx:U13>-0.04246</PDBx:U13>
         <PDBx:U22>0.24328</PDBx:U22>
         <PDBx:U23>-0.02124</PDBx:U23>
         <PDBx:U33>0.19235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.24349</PDBx:U11>
         <PDBx:U12>0.09944</PDBx:U12>
         <PDBx:U13>-0.03601</PDBx:U13>
         <PDBx:U22>0.25000</PDBx:U22>
         <PDBx:U23>-0.01840</PDBx:U23>
         <PDBx:U33>0.19099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.04107</PDBx:U13>
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         <PDBx:U23>-0.02400</PDBx:U23>
         <PDBx:U33>0.19422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.30160</PDBx:U11>
         <PDBx:U12>0.10540</PDBx:U12>
         <PDBx:U13>-0.04808</PDBx:U13>
         <PDBx:U22>0.28452</PDBx:U22>
         <PDBx:U23>-0.02720</PDBx:U23>
         <PDBx:U33>0.22400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1267">
         <PDBx:U11>0.22054</PDBx:U11>
         <PDBx:U12>0.09625</PDBx:U12>
         <PDBx:U13>-0.03244</PDBx:U13>
         <PDBx:U22>0.22543</PDBx:U22>
         <PDBx:U23>-0.01363</PDBx:U23>
         <PDBx:U33>0.16986</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.26940</PDBx:U11>
         <PDBx:U12>0.09350</PDBx:U12>
         <PDBx:U13>-0.02816</PDBx:U13>
         <PDBx:U22>0.27119</PDBx:U22>
         <PDBx:U23>-0.00996</PDBx:U23>
         <PDBx:U33>0.22418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.09542</PDBx:U12>
         <PDBx:U13>-0.02675</PDBx:U13>
         <PDBx:U22>0.26691</PDBx:U22>
         <PDBx:U23>-0.00985</PDBx:U23>
         <PDBx:U33>0.20318</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.02114</PDBx:U13>
         <PDBx:U22>0.28875</PDBx:U22>
         <PDBx:U23>-0.00622</PDBx:U23>
         <PDBx:U33>0.24079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.10761</PDBx:U12>
         <PDBx:U13>-0.03801</PDBx:U13>
         <PDBx:U22>0.26716</PDBx:U22>
         <PDBx:U23>-0.02517</PDBx:U23>
         <PDBx:U33>0.19119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.04157</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.31633</PDBx:U11>
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         <PDBx:U23>-0.04490</PDBx:U23>
         <PDBx:U33>0.24915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1279">
         <PDBx:U11>0.27254</PDBx:U11>
         <PDBx:U12>0.11905</PDBx:U12>
         <PDBx:U13>-0.04712</PDBx:U13>
         <PDBx:U22>0.28919</PDBx:U22>
         <PDBx:U23>-0.03538</PDBx:U23>
         <PDBx:U33>0.19137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1280">
         <PDBx:U11>0.29290</PDBx:U11>
         <PDBx:U12>0.12110</PDBx:U12>
         <PDBx:U13>-0.04697</PDBx:U13>
         <PDBx:U22>0.32243</PDBx:U22>
         <PDBx:U23>-0.03520</PDBx:U23>
         <PDBx:U33>0.21014</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1281">
         <PDBx:U11>0.40301</PDBx:U11>
         <PDBx:U12>0.12982</PDBx:U12>
         <PDBx:U13>-0.04415</PDBx:U13>
         <PDBx:U22>0.44483</PDBx:U22>
         <PDBx:U23>-0.03942</PDBx:U23>
         <PDBx:U33>0.31703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1282">
         <PDBx:U11>0.35972</PDBx:U11>
         <PDBx:U12>0.13653</PDBx:U12>
         <PDBx:U13>-0.04711</PDBx:U13>
         <PDBx:U22>0.39373</PDBx:U22>
         <PDBx:U23>-0.04648</PDBx:U23>
         <PDBx:U33>0.26648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1283">
         <PDBx:U11>0.29653</PDBx:U11>
         <PDBx:U12>0.12018</PDBx:U12>
         <PDBx:U13>-0.05696</PDBx:U13>
         <PDBx:U22>0.31028</PDBx:U22>
         <PDBx:U23>-0.04012</PDBx:U23>
         <PDBx:U33>0.19891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.29691</PDBx:U11>
         <PDBx:U12>0.11041</PDBx:U12>
         <PDBx:U13>-0.05954</PDBx:U13>
         <PDBx:U22>0.30445</PDBx:U22>
         <PDBx:U23>-0.03517</PDBx:U23>
         <PDBx:U33>0.20095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.30057</PDBx:U11>
         <PDBx:U12>0.10489</PDBx:U12>
         <PDBx:U13>-0.05502</PDBx:U13>
         <PDBx:U22>0.32721</PDBx:U22>
         <PDBx:U23>-0.02735</PDBx:U23>
         <PDBx:U33>0.21911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.29785</PDBx:U11>
         <PDBx:U12>0.10476</PDBx:U12>
         <PDBx:U13>-0.06412</PDBx:U13>
         <PDBx:U22>0.27923</PDBx:U22>
         <PDBx:U23>-0.03827</PDBx:U23>
         <PDBx:U33>0.19065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.28749</PDBx:U11>
         <PDBx:U12>0.09392</PDBx:U12>
         <PDBx:U13>-0.05351</PDBx:U13>
         <PDBx:U22>0.30928</PDBx:U22>
         <PDBx:U23>-0.02381</PDBx:U23>
         <PDBx:U33>0.21243</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1288">
         <PDBx:U11>0.38150</PDBx:U11>
         <PDBx:U12>0.09246</PDBx:U12>
         <PDBx:U13>-0.06208</PDBx:U13>
         <PDBx:U22>0.35671</PDBx:U22>
         <PDBx:U23>-0.03429</PDBx:U23>
         <PDBx:U33>0.27769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1289">
         <PDBx:U11>0.31524</PDBx:U11>
         <PDBx:U12>0.08716</PDBx:U12>
         <PDBx:U13>-0.05628</PDBx:U13>
         <PDBx:U22>0.31204</PDBx:U22>
         <PDBx:U23>-0.02759</PDBx:U23>
         <PDBx:U33>0.22890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1290">
         <PDBx:U11>0.28254</PDBx:U11>
         <PDBx:U12>0.12984</PDBx:U12>
         <PDBx:U13>-0.03901</PDBx:U13>
         <PDBx:U22>0.34382</PDBx:U22>
         <PDBx:U23>-0.03453</PDBx:U23>
         <PDBx:U33>0.20105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1291">
         <PDBx:U11>0.33565</PDBx:U11>
         <PDBx:U12>0.13953</PDBx:U12>
         <PDBx:U13>-0.03646</PDBx:U13>
         <PDBx:U22>0.41005</PDBx:U22>
         <PDBx:U23>-0.03832</PDBx:U23>
         <PDBx:U33>0.24742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1292">
         <PDBx:U11>0.43209</PDBx:U11>
         <PDBx:U12>0.14899</PDBx:U12>
         <PDBx:U13>-0.04505</PDBx:U13>
         <PDBx:U22>0.49544</PDBx:U22>
         <PDBx:U23>-0.04948</PDBx:U23>
         <PDBx:U33>0.32598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1293">
         <PDBx:U11>0.42018</PDBx:U11>
         <PDBx:U12>0.15936</PDBx:U12>
         <PDBx:U13>-0.04651</PDBx:U13>
         <PDBx:U22>0.48389</PDBx:U22>
         <PDBx:U23>-0.05669</PDBx:U23>
         <PDBx:U33>0.30595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1294">
         <PDBx:U11>0.32737</PDBx:U11>
         <PDBx:U12>0.13750</PDBx:U12>
         <PDBx:U13>-0.03044</PDBx:U13>
         <PDBx:U22>0.42222</PDBx:U22>
         <PDBx:U23>-0.02957</PDBx:U23>
         <PDBx:U33>0.24437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1295">
         <PDBx:U11>0.37154</PDBx:U11>
         <PDBx:U12>0.14921</PDBx:U12>
         <PDBx:U13>-0.02893</PDBx:U13>
         <PDBx:U22>0.48056</PDBx:U22>
         <PDBx:U23>-0.03376</PDBx:U23>
         <PDBx:U33>0.27645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1296">
         <PDBx:U11>0.30843</PDBx:U11>
         <PDBx:U12>0.12976</PDBx:U12>
         <PDBx:U13>-0.02208</PDBx:U13>
         <PDBx:U22>0.41049</PDBx:U22>
         <PDBx:U23>-0.01972</PDBx:U23>
         <PDBx:U33>0.24178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1297">
         <PDBx:U11>0.45147</PDBx:U11>
         <PDBx:U12>0.14077</PDBx:U12>
         <PDBx:U13>-0.05156</PDBx:U13>
         <PDBx:U22>0.50354</PDBx:U22>
         <PDBx:U23>-0.04962</PDBx:U23>
         <PDBx:U33>0.33887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1298">
         <PDBx:U11>0.44863</PDBx:U11>
         <PDBx:U12>0.14067</PDBx:U12>
         <PDBx:U13>-0.05166</PDBx:U13>
         <PDBx:U22>0.50015</PDBx:U22>
         <PDBx:U23>-0.04963</PDBx:U23>
         <PDBx:U33>0.33620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1299">
         <PDBx:U11>0.48094</PDBx:U11>
         <PDBx:U12>0.14133</PDBx:U12>
         <PDBx:U13>-0.05893</PDBx:U13>
         <PDBx:U22>0.51478</PDBx:U22>
         <PDBx:U23>-0.05917</PDBx:U23>
         <PDBx:U33>0.35162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1300">
         <PDBx:U11>0.48427</PDBx:U11>
         <PDBx:U12>0.14080</PDBx:U12>
         <PDBx:U13>-0.05891</PDBx:U13>
         <PDBx:U22>0.51867</PDBx:U22>
         <PDBx:U23>-0.05883</PDBx:U23>
         <PDBx:U33>0.35505</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1301">
         <PDBx:U11>0.49021</PDBx:U11>
         <PDBx:U12>0.12933</PDBx:U12>
         <PDBx:U13>-0.06594</PDBx:U13>
         <PDBx:U22>0.50623</PDBx:U22>
         <PDBx:U23>-0.05836</PDBx:U23>
         <PDBx:U33>0.35807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1302">
         <PDBx:U11>0.49088</PDBx:U11>
         <PDBx:U12>0.12911</PDBx:U12>
         <PDBx:U13>-0.06600</PDBx:U13>
         <PDBx:U22>0.50686</PDBx:U22>
         <PDBx:U23>-0.05827</PDBx:U23>
         <PDBx:U33>0.35878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1303">
         <PDBx:U11>0.49476</PDBx:U11>
         <PDBx:U12>0.11997</PDBx:U12>
         <PDBx:U13>-0.06611</PDBx:U13>
         <PDBx:U22>0.52056</PDBx:U22>
         <PDBx:U23>-0.05128</PDBx:U23>
         <PDBx:U33>0.36982</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U23>-0.05129</PDBx:U23>
         <PDBx:U33>0.36570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.55164</PDBx:U11>
         <PDBx:U12>0.14119</PDBx:U12>
         <PDBx:U13>-0.05794</PDBx:U13>
         <PDBx:U22>0.59559</PDBx:U22>
         <PDBx:U23>-0.06097</PDBx:U23>
         <PDBx:U33>0.41268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.53469</PDBx:U11>
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         <PDBx:U13>-0.05780</PDBx:U13>
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         <PDBx:U23>-0.05926</PDBx:U23>
         <PDBx:U33>0.39724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.05132</PDBx:U23>
         <PDBx:U33>0.41890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.06850</PDBx:U23>
         <PDBx:U33>0.41200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.05303</PDBx:U23>
         <PDBx:U33>0.43208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.61457</PDBx:U11>
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         <PDBx:U23>-0.07800</PDBx:U23>
         <PDBx:U33>0.45153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1311">
         <PDBx:U11>0.52579</PDBx:U11>
         <PDBx:U12>0.12028</PDBx:U12>
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         <PDBx:U23>-0.04767</PDBx:U23>
         <PDBx:U33>0.38039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U23>-0.08505</PDBx:U23>
         <PDBx:U33>0.44697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U33>0.36214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.05586</PDBx:U13>
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         <PDBx:U23>-0.07753</PDBx:U23>
         <PDBx:U33>0.51297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U23>-0.06496</PDBx:U23>
         <PDBx:U33>0.34812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U33>0.37112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.06989</PDBx:U23>
         <PDBx:U33>0.34845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U33>0.31669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.53031</PDBx:U11>
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         <PDBx:U23>-0.06461</PDBx:U23>
         <PDBx:U33>0.38237</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1320">
         <PDBx:U11>0.49968</PDBx:U11>
         <PDBx:U12>0.13402</PDBx:U12>
         <PDBx:U13>-0.08127</PDBx:U13>
         <PDBx:U22>0.44120</PDBx:U22>
         <PDBx:U23>-0.07104</PDBx:U23>
         <PDBx:U33>0.34660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1321">
         <PDBx:U11>0.51048</PDBx:U11>
         <PDBx:U12>0.11108</PDBx:U12>
         <PDBx:U13>-0.08458</PDBx:U13>
         <PDBx:U22>0.47660</PDBx:U22>
         <PDBx:U23>-0.07305</PDBx:U23>
         <PDBx:U33>0.34554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1322">
         <PDBx:U11>0.50907</PDBx:U11>
         <PDBx:U12>0.11124</PDBx:U12>
         <PDBx:U13>-0.08461</PDBx:U13>
         <PDBx:U22>0.47479</PDBx:U22>
         <PDBx:U23>-0.07323</PDBx:U23>
         <PDBx:U33>0.34388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1323">
         <PDBx:U11>0.52724</PDBx:U11>
         <PDBx:U12>0.10163</PDBx:U12>
         <PDBx:U13>-0.09163</PDBx:U13>
         <PDBx:U22>0.48062</PDBx:U22>
         <PDBx:U23>-0.07874</PDBx:U23>
         <PDBx:U33>0.34916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1324">
         <PDBx:U11>0.52745</PDBx:U11>
         <PDBx:U12>0.10151</PDBx:U12>
         <PDBx:U13>-0.09172</PDBx:U13>
         <PDBx:U22>0.48035</PDBx:U22>
         <PDBx:U23>-0.07879</PDBx:U23>
         <PDBx:U33>0.34928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1325">
         <PDBx:U11>0.53976</PDBx:U11>
         <PDBx:U12>0.08722</PDBx:U12>
         <PDBx:U13>-0.09637</PDBx:U13>
         <PDBx:U22>0.49770</PDBx:U22>
         <PDBx:U23>-0.07407</PDBx:U23>
         <PDBx:U33>0.36721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1326">
         <PDBx:U11>0.53635</PDBx:U11>
         <PDBx:U12>0.08723</PDBx:U12>
         <PDBx:U13>-0.09631</PDBx:U13>
         <PDBx:U22>0.49358</PDBx:U22>
         <PDBx:U23>-0.07400</PDBx:U23>
         <PDBx:U33>0.36392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1327">
         <PDBx:U11>0.54166</PDBx:U11>
         <PDBx:U12>0.08583</PDBx:U12>
         <PDBx:U13>-0.09366</PDBx:U13>
         <PDBx:U22>0.52208</PDBx:U22>
         <PDBx:U23>-0.06575</PDBx:U23>
         <PDBx:U33>0.38388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1328">
         <PDBx:U11>0.53749</PDBx:U11>
         <PDBx:U12>0.08593</PDBx:U12>
         <PDBx:U13>-0.09346</PDBx:U13>
         <PDBx:U22>0.51636</PDBx:U22>
         <PDBx:U23>-0.06566</PDBx:U23>
         <PDBx:U33>0.37994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1329">
         <PDBx:U11>0.52174</PDBx:U11>
         <PDBx:U12>0.10488</PDBx:U12>
         <PDBx:U13>-0.09057</PDBx:U13>
         <PDBx:U22>0.48848</PDBx:U22>
         <PDBx:U23>-0.08195</PDBx:U23>
         <PDBx:U33>0.33674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1330">
         <PDBx:U11>0.52618</PDBx:U11>
         <PDBx:U12>0.10388</PDBx:U12>
         <PDBx:U13>-0.09115</PDBx:U13>
         <PDBx:U22>0.49208</PDBx:U22>
         <PDBx:U23>-0.08204</PDBx:U23>
         <PDBx:U33>0.34079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1331">
         <PDBx:U11>0.56679</PDBx:U11>
         <PDBx:U12>0.12013</PDBx:U12>
         <PDBx:U13>-0.08319</PDBx:U13>
         <PDBx:U22>0.54124</PDBx:U22>
         <PDBx:U23>-0.08404</PDBx:U23>
         <PDBx:U33>0.38247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1332">
         <PDBx:U11>0.56824</PDBx:U11>
         <PDBx:U12>0.11455</PDBx:U12>
         <PDBx:U13>-0.08956</PDBx:U13>
         <PDBx:U22>0.52094</PDBx:U22>
         <PDBx:U23>-0.09110</PDBx:U23>
         <PDBx:U33>0.37057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1333">
         <PDBx:U11>0.56157</PDBx:U11>
         <PDBx:U12>0.12625</PDBx:U12>
         <PDBx:U13>-0.07687</PDBx:U13>
         <PDBx:U22>0.55306</PDBx:U22>
         <PDBx:U23>-0.07753</PDBx:U23>
         <PDBx:U33>0.39095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1334">
         <PDBx:U11>0.51937</PDBx:U11>
         <PDBx:U12>0.12144</PDBx:U12>
         <PDBx:U13>-0.08960</PDBx:U13>
         <PDBx:U22>0.45486</PDBx:U22>
         <PDBx:U23>-0.09392</PDBx:U23>
         <PDBx:U33>0.32151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1335">
         <PDBx:U11>0.58868</PDBx:U11>
         <PDBx:U12>0.12574</PDBx:U12>
         <PDBx:U13>-0.08352</PDBx:U13>
         <PDBx:U22>0.55270</PDBx:U22>
         <PDBx:U23>-0.09246</PDBx:U23>
         <PDBx:U33>0.39168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1336">
         <PDBx:U11>0.59180</PDBx:U11>
         <PDBx:U12>0.11607</PDBx:U12>
         <PDBx:U13>-0.08868</PDBx:U13>
         <PDBx:U22>0.55139</PDBx:U22>
         <PDBx:U23>-0.09513</PDBx:U23>
         <PDBx:U33>0.38435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1337">
         <PDBx:U11>0.46857</PDBx:U11>
         <PDBx:U12>0.07651</PDBx:U12>
         <PDBx:U13>-0.10354</PDBx:U13>
         <PDBx:U22>0.40551</PDBx:U22>
         <PDBx:U23>-0.07943</PDBx:U23>
         <PDBx:U33>0.28526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1338">
         <PDBx:U11>0.52349</PDBx:U11>
         <PDBx:U12>0.06223</PDBx:U12>
         <PDBx:U13>-0.10883</PDBx:U13>
         <PDBx:U22>0.46217</PDBx:U22>
         <PDBx:U23>-0.07672</PDBx:U23>
         <PDBx:U33>0.34561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1339">
         <PDBx:U11>0.54893</PDBx:U11>
         <PDBx:U12>0.05009</PDBx:U12>
         <PDBx:U13>-0.11744</PDBx:U13>
         <PDBx:U22>0.47697</PDBx:U22>
         <PDBx:U23>-0.08368</PDBx:U23>
         <PDBx:U33>0.36018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1340">
         <PDBx:U11>0.52839</PDBx:U11>
         <PDBx:U12>0.05272</PDBx:U12>
         <PDBx:U13>-0.11871</PDBx:U13>
         <PDBx:U22>0.44083</PDBx:U22>
         <PDBx:U23>-0.09092</PDBx:U23>
         <PDBx:U33>0.32508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1341">
         <PDBx:U11>0.55792</PDBx:U11>
         <PDBx:U12>0.05861</PDBx:U12>
         <PDBx:U13>-0.10757</PDBx:U13>
         <PDBx:U22>0.47528</PDBx:U22>
         <PDBx:U23>-0.07517</PDBx:U23>
         <PDBx:U33>0.37876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1342">
         <PDBx:U11>0.51996</PDBx:U11>
         <PDBx:U12>0.05932</PDBx:U12>
         <PDBx:U13>-0.10923</PDBx:U13>
         <PDBx:U22>0.40229</PDBx:U22>
         <PDBx:U23>-0.08126</PDBx:U23>
         <PDBx:U33>0.32404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1343">
         <PDBx:U11>0.58649</PDBx:U11>
         <PDBx:U12>0.04634</PDBx:U12>
         <PDBx:U13>-0.11544</PDBx:U13>
         <PDBx:U22>0.44683</PDBx:U22>
         <PDBx:U23>-0.08648</PDBx:U23>
         <PDBx:U33>0.37888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1344">
         <PDBx:U11>0.63633</PDBx:U11>
         <PDBx:U12>0.07320</PDBx:U12>
         <PDBx:U13>-0.10540</PDBx:U13>
         <PDBx:U22>0.50861</PDBx:U22>
         <PDBx:U23>-0.08136</PDBx:U23>
         <PDBx:U33>0.43787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1345">
         <PDBx:U11>0.66934</PDBx:U11>
         <PDBx:U12>0.04786</PDBx:U12>
         <PDBx:U13>-0.11710</PDBx:U13>
         <PDBx:U22>0.49731</PDBx:U22>
         <PDBx:U23>-0.09072</PDBx:U23>
         <PDBx:U33>0.44680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1346">
         <PDBx:U11>0.69275</PDBx:U11>
         <PDBx:U12>0.07564</PDBx:U12>
         <PDBx:U13>-0.10855</PDBx:U13>
         <PDBx:U22>0.53410</PDBx:U22>
         <PDBx:U23>-0.08574</PDBx:U23>
         <PDBx:U33>0.48049</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1347">
         <PDBx:U11>0.71525</PDBx:U11>
         <PDBx:U12>0.06321</PDBx:U12>
         <PDBx:U13>-0.11407</PDBx:U13>
         <PDBx:U22>0.53402</PDBx:U22>
         <PDBx:U23>-0.08998</PDBx:U23>
         <PDBx:U33>0.49044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1348">
         <PDBx:U11>0.83148</PDBx:U11>
         <PDBx:U12>0.06603</PDBx:U12>
         <PDBx:U13>-0.11741</PDBx:U13>
         <PDBx:U22>0.61906</PDBx:U22>
         <PDBx:U23>-0.09326</PDBx:U23>
         <PDBx:U33>0.59273</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1349">
         <PDBx:U11>0.54511</PDBx:U11>
         <PDBx:U12>0.03640</PDBx:U12>
         <PDBx:U13>-0.12384</PDBx:U13>
         <PDBx:U22>0.48198</PDBx:U22>
         <PDBx:U23>-0.08196</PDBx:U23>
         <PDBx:U33>0.36480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1350">
         <PDBx:U11>0.60147</PDBx:U11>
         <PDBx:U12>0.02108</PDBx:U12>
         <PDBx:U13>-0.13276</PDBx:U13>
         <PDBx:U22>0.52588</PDBx:U22>
         <PDBx:U23>-0.08856</PDBx:U23>
         <PDBx:U33>0.41353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1351">
         <PDBx:U11>0.63680</PDBx:U11>
         <PDBx:U12>0.00700</PDBx:U12>
         <PDBx:U13>-0.13247</PDBx:U13>
         <PDBx:U22>0.54303</PDBx:U22>
         <PDBx:U23>-0.08733</PDBx:U23>
         <PDBx:U33>0.45288</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>302</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1352">
         <PDBx:U11>0.57006</PDBx:U11>
         <PDBx:U12>0.00782</PDBx:U12>
         <PDBx:U13>-0.12289</PDBx:U13>
         <PDBx:U22>0.48232</PDBx:U22>
         <PDBx:U23>-0.07869</PDBx:U23>
         <PDBx:U33>0.40131</PDBx:U33>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1369">
         <PDBx:U11>0.77781</PDBx:U11>
         <PDBx:U12>-0.07389</PDBx:U12>
         <PDBx:U13>-0.14029</PDBx:U13>
         <PDBx:U22>0.73099</PDBx:U22>
         <PDBx:U23>-0.08048</PDBx:U23>
         <PDBx:U33>0.67390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>304</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1370">
         <PDBx:U11>0.86564</PDBx:U11>
         <PDBx:U12>-0.11456</PDBx:U12>
         <PDBx:U13>-0.13050</PDBx:U13>
         <PDBx:U22>0.75998</PDBx:U22>
         <PDBx:U23>-0.08403</PDBx:U23>
         <PDBx:U33>0.74971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1371">
         <PDBx:U11>0.93698</PDBx:U11>
         <PDBx:U12>-0.13234</PDBx:U12>
         <PDBx:U13>-0.11867</PDBx:U13>
         <PDBx:U22>0.82388</PDBx:U22>
         <PDBx:U23>-0.07947</PDBx:U23>
         <PDBx:U33>0.83180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1372">
         <PDBx:U11>0.91944</PDBx:U11>
         <PDBx:U12>-0.13286</PDBx:U12>
         <PDBx:U13>-0.10732</PDBx:U13>
         <PDBx:U22>0.85048</PDBx:U22>
         <PDBx:U23>-0.07070</PDBx:U23>
         <PDBx:U33>0.85509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1373">
         <PDBx:U11>0.98338</PDBx:U11>
         <PDBx:U12>-0.12862</PDBx:U12>
         <PDBx:U13>-0.11305</PDBx:U13>
         <PDBx:U22>0.95359</PDBx:U22>
         <PDBx:U23>-0.06945</PDBx:U23>
         <PDBx:U33>0.94554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1374">
         <PDBx:U11>1.05515</PDBx:U11>
         <PDBx:U12>-0.15652</PDBx:U12>
         <PDBx:U13>-0.12583</PDBx:U13>
         <PDBx:U22>0.92846</PDBx:U22>
         <PDBx:U23>-0.08606</PDBx:U23>
         <PDBx:U33>0.94786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1375">
         <PDBx:U11>1.13848</PDBx:U11>
         <PDBx:U12>-0.17726</PDBx:U12>
         <PDBx:U13>-0.11309</PDBx:U13>
         <PDBx:U22>0.99676</PDBx:U22>
         <PDBx:U23>-0.08217</PDBx:U23>
         <PDBx:U33>1.03571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1376">
         <PDBx:U11>1.16716</PDBx:U11>
         <PDBx:U12>-0.19039</PDBx:U12>
         <PDBx:U13>-0.10297</PDBx:U13>
         <PDBx:U22>1.06246</PDBx:U22>
         <PDBx:U23>-0.07695</PDBx:U23>
         <PDBx:U33>1.10388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1377">
         <PDBx:U11>1.22047</PDBx:U11>
         <PDBx:U12>-0.18372</PDBx:U12>
         <PDBx:U13>-0.11090</PDBx:U13>
         <PDBx:U22>1.02703</PDBx:U22>
         <PDBx:U23>-0.08362</PDBx:U23>
         <PDBx:U33>1.08219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1378">
         <PDBx:U11>1.22278</PDBx:U11>
         <PDBx:U12>-0.21026</PDBx:U12>
         <PDBx:U13>-0.08925</PDBx:U13>
         <PDBx:U22>1.10481</PDBx:U22>
         <PDBx:U23>-0.07370</PDBx:U23>
         <PDBx:U33>1.16265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1379">
         <PDBx:U11>1.30419</PDBx:U11>
         <PDBx:U12>-0.20384</PDBx:U12>
         <PDBx:U13>-0.09856</PDBx:U13>
         <PDBx:U22>1.09483</PDBx:U22>
         <PDBx:U23>-0.07930</PDBx:U23>
         <PDBx:U33>1.16632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1380">
         <PDBx:U11>1.29773</PDBx:U11>
         <PDBx:U12>-0.21760</PDBx:U12>
         <PDBx:U13>-0.08695</PDBx:U13>
         <PDBx:U22>1.12667</PDBx:U22>
         <PDBx:U23>-0.07460</PDBx:U23>
         <PDBx:U33>1.19859</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1381">
         <PDBx:U11>1.32478</PDBx:U11>
         <PDBx:U12>-0.23850</PDBx:U12>
         <PDBx:U13>-0.07267</PDBx:U13>
         <PDBx:U22>1.13843</PDBx:U22>
         <PDBx:U23>-0.07062</PDBx:U23>
         <PDBx:U33>1.22520</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>305</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1382">
         <PDBx:U11>0.86969</PDBx:U11>
         <PDBx:U12>-0.13789</PDBx:U12>
         <PDBx:U13>-0.09136</PDBx:U13>
         <PDBx:U22>0.79291</PDBx:U22>
         <PDBx:U23>-0.06469</PDBx:U23>
         <PDBx:U33>0.80918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1383">
         <PDBx:U11>0.88000</PDBx:U11>
         <PDBx:U12>-0.13806</PDBx:U12>
         <PDBx:U13>-0.07808</PDBx:U13>
         <PDBx:U22>0.84115</PDBx:U22>
         <PDBx:U23>-0.05730</PDBx:U23>
         <PDBx:U33>0.85702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1384">
         <PDBx:U11>0.95052</PDBx:U11>
         <PDBx:U12>-0.16211</PDBx:U12>
         <PDBx:U13>-0.07122</PDBx:U13>
         <PDBx:U22>0.92637</PDBx:U22>
         <PDBx:U23>-0.05733</PDBx:U23>
         <PDBx:U33>0.95416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1385">
         <PDBx:U11>0.94725</PDBx:U11>
         <PDBx:U12>-0.16701</PDBx:U12>
         <PDBx:U13>-0.05487</PDBx:U13>
         <PDBx:U22>0.93923</PDBx:U22>
         <PDBx:U23>-0.05214</PDBx:U23>
         <PDBx:U33>0.97340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1386">
         <PDBx:U11>0.94824</PDBx:U11>
         <PDBx:U12>-0.12817</PDBx:U12>
         <PDBx:U13>-0.06335</PDBx:U13>
         <PDBx:U22>0.89463</PDBx:U22>
         <PDBx:U23>-0.05133</PDBx:U23>
         <PDBx:U33>0.91395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1387">
         <PDBx:U11>0.95583</PDBx:U11>
         <PDBx:U12>-0.11563</PDBx:U12>
         <PDBx:U13>-0.05442</PDBx:U13>
         <PDBx:U22>0.94043</PDBx:U22>
         <PDBx:U23>-0.04492</PDBx:U23>
         <PDBx:U33>0.95298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1388">
         <PDBx:U11>0.99579</PDBx:U11>
         <PDBx:U12>-0.12399</PDBx:U12>
         <PDBx:U13>-0.04079</PDBx:U13>
         <PDBx:U22>1.00009</PDBx:U22>
         <PDBx:U23>-0.04128</PDBx:U23>
         <PDBx:U33>1.01973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1389">
         <PDBx:U11>0.94934</PDBx:U11>
         <PDBx:U12>-0.09552</PDBx:U12>
         <PDBx:U13>-0.06127</PDBx:U13>
         <PDBx:U22>0.94382</PDBx:U22>
         <PDBx:U23>-0.04369</PDBx:U23>
         <PDBx:U33>0.94337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1390">
         <PDBx:U11>1.02959</PDBx:U11>
         <PDBx:U12>-0.16530</PDBx:U12>
         <PDBx:U13>-0.05697</PDBx:U13>
         <PDBx:U22>0.85018</PDBx:U22>
         <PDBx:U23>-0.05513</PDBx:U23>
         <PDBx:U33>0.90732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1391">
         <PDBx:U11>1.07365</PDBx:U11>
         <PDBx:U12>-0.14981</PDBx:U12>
         <PDBx:U13>-0.06758</PDBx:U13>
         <PDBx:U22>0.85673</PDBx:U22>
         <PDBx:U23>-0.05762</PDBx:U23>
         <PDBx:U33>0.91381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1392">
         <PDBx:U11>1.04477</PDBx:U11>
         <PDBx:U12>-0.13100</PDBx:U12>
         <PDBx:U13>-0.08155</PDBx:U13>
         <PDBx:U22>0.84574</PDBx:U22>
         <PDBx:U23>-0.06287</PDBx:U23>
         <PDBx:U33>0.88893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1393">
         <PDBx:U11>1.03482</PDBx:U11>
         <PDBx:U12>-0.12913</PDBx:U12>
         <PDBx:U13>-0.08380</PDBx:U13>
         <PDBx:U22>0.87704</PDBx:U22>
         <PDBx:U23>-0.06342</PDBx:U23>
         <PDBx:U33>0.90915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1394">
         <PDBx:U11>1.04147</PDBx:U11>
         <PDBx:U12>-0.13786</PDBx:U12>
         <PDBx:U13>-0.05842</PDBx:U13>
         <PDBx:U22>0.80907</PDBx:U22>
         <PDBx:U23>-0.05121</PDBx:U23>
         <PDBx:U33>0.86561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1395">
         <PDBx:U11>1.05024</PDBx:U11>
         <PDBx:U12>-0.14922</PDBx:U12>
         <PDBx:U13>-0.05445</PDBx:U13>
         <PDBx:U22>0.76833</PDBx:U22>
         <PDBx:U23>-0.04837</PDBx:U23>
         <PDBx:U33>0.83915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1396">
         <PDBx:U11>0.90346</PDBx:U11>
         <PDBx:U12>-0.13833</PDBx:U12>
         <PDBx:U13>-0.04597</PDBx:U13>
         <PDBx:U22>0.61110</PDBx:U22>
         <PDBx:U23>-0.04181</PDBx:U23>
         <PDBx:U33>0.67879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1397">
         <PDBx:U11>0.83623</PDBx:U11>
         <PDBx:U12>-0.11521</PDBx:U12>
         <PDBx:U13>-0.05744</PDBx:U13>
         <PDBx:U22>0.53057</PDBx:U22>
         <PDBx:U23>-0.04330</PDBx:U23>
         <PDBx:U33>0.59385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1398">
         <PDBx:U11>0.81592</PDBx:U11>
         <PDBx:U12>-0.10247</PDBx:U12>
         <PDBx:U13>-0.05406</PDBx:U13>
         <PDBx:U22>0.50405</PDBx:U22>
         <PDBx:U23>-0.03872</PDBx:U23>
         <PDBx:U33>0.56323</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1399">
         <PDBx:U11>0.80321</PDBx:U11>
         <PDBx:U12>-0.08204</PDBx:U12>
         <PDBx:U13>-0.06491</PDBx:U13>
         <PDBx:U22>0.48229</PDBx:U22>
         <PDBx:U23>-0.04068</PDBx:U23>
         <PDBx:U33>0.53834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1400">
         <PDBx:U11>0.82501</PDBx:U11>
         <PDBx:U12>-0.11061</PDBx:U12>
         <PDBx:U13>-0.03952</PDBx:U13>
         <PDBx:U22>0.51635</PDBx:U22>
         <PDBx:U23>-0.03275</PDBx:U23>
         <PDBx:U33>0.57447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1401">
         <PDBx:U11>1.00107</PDBx:U11>
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         <PDBx:U13>-0.09065</PDBx:U13>
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         <PDBx:U23>-0.06649</PDBx:U23>
         <PDBx:U33>0.81416</PDBx:U33>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.92863</PDBx:U11>
         <PDBx:U12>-0.09782</PDBx:U12>
         <PDBx:U13>-0.10182</PDBx:U13>
         <PDBx:U22>0.71020</PDBx:U22>
         <PDBx:U23>-0.07187</PDBx:U23>
         <PDBx:U33>0.74006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.79936</PDBx:U11>
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         <PDBx:U13>-0.09603</PDBx:U13>
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         <PDBx:U23>-0.06640</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.85114</PDBx:U11>
         <PDBx:U12>-0.07146</PDBx:U12>
         <PDBx:U13>-0.09006</PDBx:U13>
         <PDBx:U22>0.63198</PDBx:U22>
         <PDBx:U23>-0.06201</PDBx:U23>
         <PDBx:U33>0.65657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.93135</PDBx:U11>
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         <PDBx:U13>-0.11363</PDBx:U13>
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         <PDBx:U23>-0.07994</PDBx:U23>
         <PDBx:U33>0.70741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>1.08794</PDBx:U11>
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         <PDBx:U13>-0.12240</PDBx:U13>
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         <PDBx:U23>-0.08760</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>1.12723</PDBx:U11>
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         <PDBx:U23>-0.08834</PDBx:U23>
         <PDBx:U33>0.92257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>1.15306</PDBx:U11>
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         <PDBx:U23>-0.08957</PDBx:U23>
         <PDBx:U33>0.90399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.66042</PDBx:U11>
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         <PDBx:U13>-0.09880</PDBx:U13>
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         <PDBx:U23>-0.06661</PDBx:U23>
         <PDBx:U33>0.50031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.60838</PDBx:U11>
         <PDBx:U12>-0.04918</PDBx:U12>
         <PDBx:U13>-0.09265</PDBx:U13>
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         <PDBx:U23>-0.06086</PDBx:U23>
         <PDBx:U33>0.46105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.03120</PDBx:U12>
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         <PDBx:U23>-0.06555</PDBx:U23>
         <PDBx:U33>0.34811</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.07138</PDBx:U23>
         <PDBx:U33>0.40292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.71521</PDBx:U11>
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         <PDBx:U23>-0.05454</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.04705</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.74920</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.03599</PDBx:U23>
         <PDBx:U33>0.76005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1418">
         <PDBx:U11>0.54422</PDBx:U11>
         <PDBx:U12>-0.01434</PDBx:U12>
         <PDBx:U13>-0.09846</PDBx:U13>
         <PDBx:U22>0.41064</PDBx:U22>
         <PDBx:U23>-0.06319</PDBx:U23>
         <PDBx:U33>0.38247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1419">
         <PDBx:U11>0.56923</PDBx:U11>
         <PDBx:U12>0.00314</PDBx:U12>
         <PDBx:U13>-0.10270</PDBx:U13>
         <PDBx:U22>0.45158</PDBx:U22>
         <PDBx:U23>-0.06558</PDBx:U23>
         <PDBx:U33>0.40674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1420">
         <PDBx:U11>0.52036</PDBx:U11>
         <PDBx:U12>0.00879</PDBx:U12>
         <PDBx:U13>-0.09547</PDBx:U13>
         <PDBx:U22>0.44179</PDBx:U22>
         <PDBx:U23>-0.05729</PDBx:U23>
         <PDBx:U33>0.38550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1421">
         <PDBx:U11>0.46339</PDBx:U11>
         <PDBx:U12>0.00725</PDBx:U12>
         <PDBx:U13>-0.08563</PDBx:U13>
         <PDBx:U22>0.39075</PDBx:U22>
         <PDBx:U23>-0.05027</PDBx:U23>
         <PDBx:U33>0.34140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1422">
         <PDBx:U11>0.53754</PDBx:U11>
         <PDBx:U12>0.01856</PDBx:U12>
         <PDBx:U13>-0.10363</PDBx:U13>
         <PDBx:U22>0.39645</PDBx:U22>
         <PDBx:U23>-0.06833</PDBx:U23>
         <PDBx:U33>0.35482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1423">
         <PDBx:U11>0.59491</PDBx:U11>
         <PDBx:U12>0.01656</PDBx:U12>
         <PDBx:U13>-0.11170</PDBx:U13>
         <PDBx:U22>0.41244</PDBx:U22>
         <PDBx:U23>-0.07661</PDBx:U23>
         <PDBx:U33>0.38392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1424">
         <PDBx:U11>0.62769</PDBx:U11>
         <PDBx:U12>0.03242</PDBx:U12>
         <PDBx:U13>-0.11022</PDBx:U13>
         <PDBx:U22>0.42845</PDBx:U22>
         <PDBx:U23>-0.07582</PDBx:U23>
         <PDBx:U33>0.40677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1425">
         <PDBx:U11>0.73945</PDBx:U11>
         <PDBx:U12>0.03093</PDBx:U12>
         <PDBx:U13>-0.11371</PDBx:U13>
         <PDBx:U22>0.50594</PDBx:U22>
         <PDBx:U23>-0.07799</PDBx:U23>
         <PDBx:U33>0.50188</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1426">
         <PDBx:U11>0.74964</PDBx:U11>
         <PDBx:U12>0.04513</PDBx:U12>
         <PDBx:U13>-0.11476</PDBx:U13>
         <PDBx:U22>0.50189</PDBx:U22>
         <PDBx:U23>-0.07744</PDBx:U23>
         <PDBx:U33>0.50554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1427">
         <PDBx:U11>0.77281</PDBx:U11>
         <PDBx:U12>0.06063</PDBx:U12>
         <PDBx:U13>-0.11196</PDBx:U13>
         <PDBx:U22>0.54246</PDBx:U22>
         <PDBx:U23>-0.07536</PDBx:U23>
         <PDBx:U33>0.53847</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1428">
         <PDBx:U11>0.81028</PDBx:U11>
         <PDBx:U12>0.04374</PDBx:U12>
         <PDBx:U13>-0.11933</PDBx:U13>
         <PDBx:U22>0.53148</PDBx:U22>
         <PDBx:U23>-0.07892</PDBx:U23>
         <PDBx:U33>0.55053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1429">
         <PDBx:U11>0.48297</PDBx:U11>
         <PDBx:U12>0.01504</PDBx:U12>
         <PDBx:U13>-0.10052</PDBx:U13>
         <PDBx:U22>0.42883</PDBx:U22>
         <PDBx:U23>-0.05819</PDBx:U23>
         <PDBx:U33>0.35513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1430">
         <PDBx:U11>0.45795</PDBx:U11>
         <PDBx:U12>0.02152</PDBx:U12>
         <PDBx:U13>-0.09545</PDBx:U13>
         <PDBx:U22>0.43906</PDBx:U22>
         <PDBx:U23>-0.04995</PDBx:U23>
         <PDBx:U33>0.35421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1431">
         <PDBx:U11>0.46521</PDBx:U11>
         <PDBx:U12>0.03797</PDBx:U12>
         <PDBx:U13>-0.09769</PDBx:U13>
         <PDBx:U22>0.45371</PDBx:U22>
         <PDBx:U23>-0.05139</PDBx:U23>
         <PDBx:U33>0.35158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1432">
         <PDBx:U11>0.47251</PDBx:U11>
         <PDBx:U12>0.04033</PDBx:U12>
         <PDBx:U13>-0.10626</PDBx:U13>
         <PDBx:U22>0.45545</PDBx:U22>
         <PDBx:U23>-0.05889</PDBx:U23>
         <PDBx:U33>0.34193</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1433">
         <PDBx:U11>0.47568</PDBx:U11>
         <PDBx:U12>0.01121</PDBx:U12>
         <PDBx:U13>-0.10005</PDBx:U13>
         <PDBx:U22>0.48272</PDBx:U22>
         <PDBx:U23>-0.04772</PDBx:U23>
         <PDBx:U33>0.39248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.49703</PDBx:U11>
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         <PDBx:U23>-0.04660</PDBx:U23>
         <PDBx:U33>0.42610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.04479</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.37798</PDBx:U11>
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         <PDBx:U13>-0.08930</PDBx:U13>
         <PDBx:U22>0.38819</PDBx:U22>
         <PDBx:U23>-0.04512</PDBx:U23>
         <PDBx:U33>0.26748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.39165</PDBx:U11>
         <PDBx:U12>0.06343</PDBx:U12>
         <PDBx:U13>-0.09532</PDBx:U13>
         <PDBx:U22>0.42491</PDBx:U22>
         <PDBx:U23>-0.04377</PDBx:U23>
         <PDBx:U33>0.28430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.39715</PDBx:U11>
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         <PDBx:U13>-0.09660</PDBx:U13>
         <PDBx:U22>0.44941</PDBx:U22>
         <PDBx:U23>-0.03767</PDBx:U23>
         <PDBx:U33>0.30869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.41380</PDBx:U11>
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         <PDBx:U13>-0.07906</PDBx:U13>
         <PDBx:U22>0.43616</PDBx:U22>
         <PDBx:U23>-0.03687</PDBx:U23>
         <PDBx:U33>0.31786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1441">
         <PDBx:U11>0.43583</PDBx:U11>
         <PDBx:U12>0.07805</PDBx:U12>
         <PDBx:U13>-0.07404</PDBx:U13>
         <PDBx:U22>0.44099</PDBx:U22>
         <PDBx:U23>-0.03809</PDBx:U23>
         <PDBx:U33>0.33329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1442">
         <PDBx:U11>0.37062</PDBx:U11>
         <PDBx:U12>0.08970</PDBx:U12>
         <PDBx:U13>-0.07764</PDBx:U13>
         <PDBx:U22>0.36484</PDBx:U22>
         <PDBx:U23>-0.04606</PDBx:U23>
         <PDBx:U33>0.24956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1443">
         <PDBx:U11>0.55338</PDBx:U11>
         <PDBx:U12>0.06806</PDBx:U12>
         <PDBx:U13>-0.07365</PDBx:U13>
         <PDBx:U22>0.53513</PDBx:U22>
         <PDBx:U23>-0.03940</PDBx:U23>
         <PDBx:U33>0.44627</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1444">
         <PDBx:U11>0.40106</PDBx:U11>
         <PDBx:U12>0.07200</PDBx:U12>
         <PDBx:U13>-0.09878</PDBx:U13>
         <PDBx:U22>0.43249</PDBx:U22>
         <PDBx:U23>-0.04946</PDBx:U23>
         <PDBx:U33>0.27523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1445">
         <PDBx:U11>0.45406</PDBx:U11>
         <PDBx:U12>0.07208</PDBx:U12>
         <PDBx:U13>-0.10060</PDBx:U13>
         <PDBx:U22>0.50538</PDBx:U22>
         <PDBx:U23>-0.04567</PDBx:U23>
         <PDBx:U33>0.33065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1446">
         <PDBx:U11>0.43838</PDBx:U11>
         <PDBx:U12>0.07963</PDBx:U12>
         <PDBx:U13>-0.09157</PDBx:U13>
         <PDBx:U22>0.51108</PDBx:U22>
         <PDBx:U23>-0.03448</PDBx:U23>
         <PDBx:U33>0.33100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.40400</PDBx:U11>
         <PDBx:U12>0.07752</PDBx:U12>
         <PDBx:U13>-0.09332</PDBx:U13>
         <PDBx:U22>0.49621</PDBx:U22>
         <PDBx:U23>-0.02657</PDBx:U23>
         <PDBx:U33>0.30749</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1448">
         <PDBx:U11>0.56148</PDBx:U11>
         <PDBx:U12>0.07493</PDBx:U12>
         <PDBx:U13>-0.10179</PDBx:U13>
         <PDBx:U22>0.59942</PDBx:U22>
         <PDBx:U23>-0.05452</PDBx:U23>
         <PDBx:U33>0.41583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1449">
         <PDBx:U11>0.58924</PDBx:U11>
         <PDBx:U12>0.06531</PDBx:U12>
         <PDBx:U13>-0.11083</PDBx:U13>
         <PDBx:U22>0.60503</PDBx:U22>
         <PDBx:U23>-0.06482</PDBx:U23>
         <PDBx:U33>0.42890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
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         <PDBx:U22>0.43442</PDBx:U22>
         <PDBx:U23>-0.00596</PDBx:U23>
         <PDBx:U33>0.28443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1467">
         <PDBx:U11>0.25913</PDBx:U11>
         <PDBx:U12>0.10326</PDBx:U12>
         <PDBx:U13>-0.04195</PDBx:U13>
         <PDBx:U22>0.35159</PDBx:U22>
         <PDBx:U23>-0.00688</PDBx:U23>
         <PDBx:U33>0.20814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1468">
         <PDBx:U11>0.29671</PDBx:U11>
         <PDBx:U12>0.10582</PDBx:U12>
         <PDBx:U13>-0.03210</PDBx:U13>
         <PDBx:U22>0.39414</PDBx:U22>
         <PDBx:U23>-0.00289</PDBx:U23>
         <PDBx:U33>0.25218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1469">
         <PDBx:U11>0.22707</PDBx:U11>
         <PDBx:U12>0.10802</PDBx:U12>
         <PDBx:U13>-0.03026</PDBx:U13>
         <PDBx:U22>0.31158</PDBx:U22>
         <PDBx:U23>-0.00862</PDBx:U23>
         <PDBx:U33>0.17934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1470">
         <PDBx:U11>0.31189</PDBx:U11>
         <PDBx:U12>0.11246</PDBx:U12>
         <PDBx:U13>-0.03606</PDBx:U13>
         <PDBx:U22>0.38504</PDBx:U22>
         <PDBx:U23>-0.01728</PDBx:U23>
         <PDBx:U33>0.25138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1471">
         <PDBx:U11>0.24900</PDBx:U11>
         <PDBx:U12>0.11196</PDBx:U12>
         <PDBx:U13>-0.02997</PDBx:U13>
         <PDBx:U22>0.35788</PDBx:U22>
         <PDBx:U23>-0.00274</PDBx:U23>
         <PDBx:U33>0.19576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1472">
         <PDBx:U11>0.40032</PDBx:U11>
         <PDBx:U12>0.10939</PDBx:U12>
         <PDBx:U13>-0.03062</PDBx:U13>
         <PDBx:U22>0.52218</PDBx:U22>
         <PDBx:U23>0.00575</PDBx:U23>
         <PDBx:U33>0.35090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1473">
         <PDBx:U11>0.34061</PDBx:U11>
         <PDBx:U12>0.10335</PDBx:U12>
         <PDBx:U13>-0.03146</PDBx:U13>
         <PDBx:U22>0.46431</PDBx:U22>
         <PDBx:U23>0.01225</PDBx:U23>
         <PDBx:U33>0.30476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1474">
         <PDBx:U11>0.37395</PDBx:U11>
         <PDBx:U12>0.11418</PDBx:U12>
         <PDBx:U13>-0.03055</PDBx:U13>
         <PDBx:U22>0.50434</PDBx:U22>
         <PDBx:U23>0.00592</PDBx:U23>
         <PDBx:U33>0.31348</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1475">
         <PDBx:U11>0.23929</PDBx:U11>
         <PDBx:U12>0.10453</PDBx:U12>
         <PDBx:U13>-0.02322</PDBx:U13>
         <PDBx:U22>0.32388</PDBx:U22>
         <PDBx:U23>-0.00388</PDBx:U23>
         <PDBx:U33>0.20248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1476">
         <PDBx:U11>0.25243</PDBx:U11>
         <PDBx:U12>0.10468</PDBx:U12>
         <PDBx:U13>-0.02282</PDBx:U13>
         <PDBx:U22>0.32549</PDBx:U22>
         <PDBx:U23>-0.00811</PDBx:U23>
         <PDBx:U33>0.21407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1477">
         <PDBx:U11>0.27607</PDBx:U11>
         <PDBx:U12>0.10451</PDBx:U12>
         <PDBx:U13>-0.01640</PDBx:U13>
         <PDBx:U22>0.35728</PDBx:U22>
         <PDBx:U23>-0.00504</PDBx:U23>
         <PDBx:U33>0.24430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1478">
         <PDBx:U11>0.26548</PDBx:U11>
         <PDBx:U12>0.10360</PDBx:U12>
         <PDBx:U13>-0.01121</PDBx:U13>
         <PDBx:U22>0.35881</PDBx:U22>
         <PDBx:U23>0.00154</PDBx:U23>
         <PDBx:U33>0.23981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1479">
         <PDBx:U11>0.30599</PDBx:U11>
         <PDBx:U12>0.09940</PDBx:U12>
         <PDBx:U13>-0.02329</PDBx:U13>
         <PDBx:U22>0.36751</PDBx:U22>
         <PDBx:U23>-0.00648</PDBx:U23>
         <PDBx:U33>0.27296</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1480">
         <PDBx:U11>0.20977</PDBx:U11>
         <PDBx:U12>0.09386</PDBx:U12>
         <PDBx:U13>-0.01636</PDBx:U13>
         <PDBx:U22>0.27898</PDBx:U22>
         <PDBx:U23>0.00207</PDBx:U23>
         <PDBx:U33>0.19223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1481">
         <PDBx:U11>0.27272</PDBx:U11>
         <PDBx:U12>0.10012</PDBx:U12>
         <PDBx:U13>-0.03097</PDBx:U13>
         <PDBx:U22>0.32401</PDBx:U22>
         <PDBx:U23>-0.01010</PDBx:U23>
         <PDBx:U33>0.23120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1482">
         <PDBx:U11>0.23556</PDBx:U11>
         <PDBx:U12>0.09144</PDBx:U12>
         <PDBx:U13>-0.01055</PDBx:U13>
         <PDBx:U22>0.30650</PDBx:U22>
         <PDBx:U23>0.00503</PDBx:U23>
         <PDBx:U33>0.22578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1483">
         <PDBx:U11>0.23668</PDBx:U11>
         <PDBx:U12>0.10533</PDBx:U12>
         <PDBx:U13>-0.01774</PDBx:U13>
         <PDBx:U22>0.31053</PDBx:U22>
         <PDBx:U23>-0.00941</PDBx:U23>
         <PDBx:U33>0.20414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1484">
         <PDBx:U11>0.16918</PDBx:U11>
         <PDBx:U12>0.10329</PDBx:U12>
         <PDBx:U13>-0.01317</PDBx:U13>
         <PDBx:U22>0.24906</PDBx:U22>
         <PDBx:U23>-0.00648</PDBx:U23>
         <PDBx:U33>0.14702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1485">
         <PDBx:U11>0.16180</PDBx:U11>
         <PDBx:U12>0.10000</PDBx:U12>
         <PDBx:U13>-0.01589</PDBx:U13>
         <PDBx:U22>0.22962</PDBx:U22>
         <PDBx:U23>-0.00817</PDBx:U23>
         <PDBx:U33>0.14315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1486">
         <PDBx:U11>0.24095</PDBx:U11>
         <PDBx:U12>0.10147</PDBx:U12>
         <PDBx:U13>-0.02196</PDBx:U13>
         <PDBx:U22>0.29513</PDBx:U22>
         <PDBx:U23>-0.01304</PDBx:U23>
         <PDBx:U33>0.21292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1487">
         <PDBx:U11>0.25685</PDBx:U11>
         <PDBx:U12>0.10977</PDBx:U12>
         <PDBx:U13>-0.01273</PDBx:U13>
         <PDBx:U22>0.34581</PDBx:U22>
         <PDBx:U23>-0.01052</PDBx:U23>
         <PDBx:U33>0.23229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1488">
         <PDBx:U11>0.28514</PDBx:U11>
         <PDBx:U12>0.11505</PDBx:U12>
         <PDBx:U13>-0.00953</PDBx:U13>
         <PDBx:U22>0.38824</PDBx:U22>
         <PDBx:U23>-0.00869</PDBx:U23>
         <PDBx:U33>0.25419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1489">
         <PDBx:U11>0.30825</PDBx:U11>
         <PDBx:U12>0.11743</PDBx:U12>
         <PDBx:U13>-0.00352</PDBx:U13>
         <PDBx:U22>0.42635</PDBx:U22>
         <PDBx:U23>-0.00620</PDBx:U23>
         <PDBx:U33>0.28428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1490">
         <PDBx:U11>0.42329</PDBx:U11>
         <PDBx:U12>0.12385</PDBx:U12>
         <PDBx:U13>-0.00010</PDBx:U13>
         <PDBx:U22>0.55616</PDBx:U22>
         <PDBx:U23>-0.00350</PDBx:U23>
         <PDBx:U33>0.39003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1491">
         <PDBx:U11>0.44361</PDBx:U11>
         <PDBx:U12>0.12660</PDBx:U12>
         <PDBx:U13>0.00680</PDBx:U13>
         <PDBx:U22>0.59180</PDBx:U22>
         <PDBx:U23>-0.00140</PDBx:U23>
         <PDBx:U33>0.41669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1492">
         <PDBx:U11>0.21428</PDBx:U11>
         <PDBx:U12>0.09639</PDBx:U12>
         <PDBx:U13>-0.01197</PDBx:U13>
         <PDBx:U22>0.28672</PDBx:U22>
         <PDBx:U23>-0.00424</PDBx:U23>
         <PDBx:U33>0.20791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1493">
         <PDBx:U11>0.23067</PDBx:U11>
         <PDBx:U12>0.09461</PDBx:U12>
         <PDBx:U13>-0.01501</PDBx:U13>
         <PDBx:U22>0.29423</PDBx:U22>
         <PDBx:U23>-0.00584</PDBx:U23>
         <PDBx:U33>0.22744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1494">
         <PDBx:U11>0.20732</PDBx:U11>
         <PDBx:U12>0.09848</PDBx:U12>
         <PDBx:U13>-0.01818</PDBx:U13>
         <PDBx:U22>0.27506</PDBx:U22>
         <PDBx:U23>-0.01017</PDBx:U23>
         <PDBx:U33>0.20746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1495">
         <PDBx:U11>0.23014</PDBx:U11>
         <PDBx:U12>0.09989</PDBx:U12>
         <PDBx:U13>-0.01400</PDBx:U13>
         <PDBx:U22>0.31189</PDBx:U22>
         <PDBx:U23>-0.00895</PDBx:U23>
         <PDBx:U33>0.23892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1496">
         <PDBx:U11>0.23108</PDBx:U11>
         <PDBx:U12>0.08979</PDBx:U12>
         <PDBx:U13>-0.00973</PDBx:U13>
         <PDBx:U22>0.29755</PDBx:U22>
         <PDBx:U23>-0.00017</PDBx:U23>
         <PDBx:U33>0.23987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1497">
         <PDBx:U11>0.24379</PDBx:U11>
         <PDBx:U12>0.08980</PDBx:U12>
         <PDBx:U13>-0.01404</PDBx:U13>
         <PDBx:U22>0.30230</PDBx:U22>
         <PDBx:U23>-0.00267</PDBx:U23>
         <PDBx:U33>0.25401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1498">
         <PDBx:U11>0.22112</PDBx:U11>
         <PDBx:U12>0.08683</PDBx:U12>
         <PDBx:U13>-0.00606</PDBx:U13>
         <PDBx:U22>0.28434</PDBx:U22>
         <PDBx:U23>0.00410</PDBx:U23>
         <PDBx:U33>0.22908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1499">
         <PDBx:U11>0.22112</PDBx:U11>
         <PDBx:U12>0.10059</PDBx:U12>
         <PDBx:U13>-0.02568</PDBx:U13>
         <PDBx:U22>0.27677</PDBx:U22>
         <PDBx:U23>-0.01493</PDBx:U23>
         <PDBx:U33>0.21494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1500">
         <PDBx:U11>0.24107</PDBx:U11>
         <PDBx:U12>0.10511</PDBx:U12>
         <PDBx:U13>-0.03017</PDBx:U13>
         <PDBx:U22>0.30002</PDBx:U22>
         <PDBx:U23>-0.01930</PDBx:U23>
         <PDBx:U33>0.23950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1501">
         <PDBx:U11>0.33842</PDBx:U11>
         <PDBx:U12>0.10404</PDBx:U12>
         <PDBx:U13>-0.03654</PDBx:U13>
         <PDBx:U22>0.38900</PDBx:U22>
         <PDBx:U23>-0.01995</PDBx:U23>
         <PDBx:U33>0.33881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1502">
         <PDBx:U11>0.24790</PDBx:U11>
         <PDBx:U12>0.10047</PDBx:U12>
         <PDBx:U13>-0.03750</PDBx:U13>
         <PDBx:U22>0.28809</PDBx:U22>
         <PDBx:U23>-0.01782</PDBx:U23>
         <PDBx:U33>0.24275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1503">
         <PDBx:U11>0.20558</PDBx:U11>
         <PDBx:U12>0.11157</PDBx:U12>
         <PDBx:U13>-0.03564</PDBx:U13>
         <PDBx:U22>0.25680</PDBx:U22>
         <PDBx:U23>-0.02585</PDBx:U23>
         <PDBx:U33>0.19155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1504">
         <PDBx:U11>0.24622</PDBx:U11>
         <PDBx:U12>0.11378</PDBx:U12>
         <PDBx:U13>-0.03090</PDBx:U13>
         <PDBx:U22>0.30453</PDBx:U22>
         <PDBx:U23>-0.02605</PDBx:U23>
         <PDBx:U33>0.22631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1505">
         <PDBx:U11>0.23489</PDBx:U11>
         <PDBx:U12>0.11173</PDBx:U12>
         <PDBx:U13>-0.04387</PDBx:U13>
         <PDBx:U22>0.26349</PDBx:U22>
         <PDBx:U23>-0.02887</PDBx:U23>
         <PDBx:U33>0.20509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1506">
         <PDBx:U11>0.25908</PDBx:U11>
         <PDBx:U12>0.10817</PDBx:U12>
         <PDBx:U13>-0.04142</PDBx:U13>
         <PDBx:U22>0.31469</PDBx:U22>
         <PDBx:U23>-0.02323</PDBx:U23>
         <PDBx:U33>0.26717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1507">
         <PDBx:U11>0.26323</PDBx:U11>
         <PDBx:U12>0.10894</PDBx:U12>
         <PDBx:U13>-0.05019</PDBx:U13>
         <PDBx:U22>0.31323</PDBx:U22>
         <PDBx:U23>-0.02476</PDBx:U23>
         <PDBx:U33>0.27400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1508">
         <PDBx:U11>0.26073</PDBx:U11>
         <PDBx:U12>0.10471</PDBx:U12>
         <PDBx:U13>-0.04793</PDBx:U13>
         <PDBx:U22>0.32047</PDBx:U22>
         <PDBx:U23>-0.02084</PDBx:U23>
         <PDBx:U33>0.28510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1509">
         <PDBx:U11>0.32046</PDBx:U11>
         <PDBx:U12>0.10133</PDBx:U12>
         <PDBx:U13>-0.04930</PDBx:U13>
         <PDBx:U22>0.36919</PDBx:U22>
         <PDBx:U23>-0.01913</PDBx:U23>
         <PDBx:U33>0.33682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1510">
         <PDBx:U11>0.28303</PDBx:U11>
         <PDBx:U12>0.10879</PDBx:U12>
         <PDBx:U13>-0.05914</PDBx:U13>
         <PDBx:U22>0.30747</PDBx:U22>
         <PDBx:U23>-0.02700</PDBx:U23>
         <PDBx:U33>0.27274</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1511">
         <PDBx:U11>0.40553</PDBx:U11>
         <PDBx:U12>0.11136</PDBx:U12>
         <PDBx:U13>-0.07104</PDBx:U13>
         <PDBx:U22>0.42206</PDBx:U22>
         <PDBx:U23>-0.02960</PDBx:U23>
         <PDBx:U33>0.39467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1512">
         <PDBx:U11>0.32793</PDBx:U11>
         <PDBx:U12>0.11147</PDBx:U12>
         <PDBx:U13>-0.07237</PDBx:U13>
         <PDBx:U22>0.35978</PDBx:U22>
         <PDBx:U23>-0.02872</PDBx:U23>
         <PDBx:U33>0.33452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1513">
         <PDBx:U11>0.43238</PDBx:U11>
         <PDBx:U12>0.11325</PDBx:U12>
         <PDBx:U13>-0.07960</PDBx:U13>
         <PDBx:U22>0.42748</PDBx:U22>
         <PDBx:U23>-0.03235</PDBx:U23>
         <PDBx:U33>0.40413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1514">
         <PDBx:U11>0.21934</PDBx:U11>
         <PDBx:U12>0.10550</PDBx:U12>
         <PDBx:U13>-0.04473</PDBx:U13>
         <PDBx:U22>0.29930</PDBx:U22>
         <PDBx:U23>-0.01998</PDBx:U23>
         <PDBx:U33>0.26427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1515">
         <PDBx:U11>0.27586</PDBx:U11>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1548">
         <PDBx:U11>0.24750</PDBx:U11>
         <PDBx:U12>0.03413</PDBx:U12>
         <PDBx:U13>-0.01727</PDBx:U13>
         <PDBx:U22>0.35861</PDBx:U22>
         <PDBx:U23>-0.00635</PDBx:U23>
         <PDBx:U33>0.39361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1549">
         <PDBx:U11>0.23948</PDBx:U11>
         <PDBx:U12>0.02125</PDBx:U12>
         <PDBx:U13>-0.01793</PDBx:U13>
         <PDBx:U22>0.32411</PDBx:U22>
         <PDBx:U23>-0.00965</PDBx:U23>
         <PDBx:U33>0.37282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1550">
         <PDBx:U11>0.27666</PDBx:U11>
         <PDBx:U12>0.01649</PDBx:U12>
         <PDBx:U13>-0.03110</PDBx:U13>
         <PDBx:U22>0.35041</PDBx:U22>
         <PDBx:U23>-0.01640</PDBx:U23>
         <PDBx:U33>0.39954</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1551">
         <PDBx:U11>0.16945</PDBx:U11>
         <PDBx:U12>0.03129</PDBx:U12>
         <PDBx:U13>-0.01441</PDBx:U13>
         <PDBx:U22>0.31159</PDBx:U22>
         <PDBx:U23>-0.00446</PDBx:U23>
         <PDBx:U33>0.34672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1552">
         <PDBx:U11>0.14679</PDBx:U11>
         <PDBx:U12>0.04283</PDBx:U12>
         <PDBx:U13>-0.00856</PDBx:U13>
         <PDBx:U22>0.31460</PDBx:U22>
         <PDBx:U23>-0.00073</PDBx:U23>
         <PDBx:U33>0.33640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1553">
         <PDBx:U11>0.21167</PDBx:U11>
         <PDBx:U12>0.04493</PDBx:U12>
         <PDBx:U13>0.00674</PDBx:U13>
         <PDBx:U22>0.38230</PDBx:U22>
         <PDBx:U23>0.00749</PDBx:U23>
         <PDBx:U33>0.40140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1554">
         <PDBx:U11>0.22512</PDBx:U11>
         <PDBx:U12>0.05204</PDBx:U12>
         <PDBx:U13>-0.01856</PDBx:U13>
         <PDBx:U22>0.41412</PDBx:U22>
         <PDBx:U23>-0.00563</PDBx:U23>
         <PDBx:U33>0.42599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1555">
         <PDBx:U11>0.26481</PDBx:U11>
         <PDBx:U12>0.05487</PDBx:U12>
         <PDBx:U13>0.01234</PDBx:U13>
         <PDBx:U22>0.45782</PDBx:U22>
         <PDBx:U23>0.01032</PDBx:U23>
         <PDBx:U33>0.46227</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1556">
         <PDBx:U11>0.25114</PDBx:U11>
         <PDBx:U12>0.06288</PDBx:U12>
         <PDBx:U13>-0.01178</PDBx:U13>
         <PDBx:U22>0.46287</PDBx:U22>
         <PDBx:U23>-0.00353</PDBx:U23>
         <PDBx:U33>0.46203</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1557">
         <PDBx:U11>0.32083</PDBx:U11>
         <PDBx:U12>0.06365</PDBx:U12>
         <PDBx:U13>0.00376</PDBx:U13>
         <PDBx:U22>0.53405</PDBx:U22>
         <PDBx:U23>0.00418</PDBx:U23>
         <PDBx:U33>0.52845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1558">
         <PDBx:U11>0.25988</PDBx:U11>
         <PDBx:U12>0.06999</PDBx:U12>
         <PDBx:U13>0.00988</PDBx:U13>
         <PDBx:U22>0.48195</PDBx:U22>
         <PDBx:U23>0.00447</PDBx:U23>
         <PDBx:U33>0.46701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1559">
         <PDBx:U11>0.20458</PDBx:U11>
         <PDBx:U12>0.01595</PDBx:U12>
         <PDBx:U13>-0.00366</PDBx:U13>
         <PDBx:U22>0.27765</PDBx:U22>
         <PDBx:U23>-0.00482</PDBx:U23>
         <PDBx:U33>0.33777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1560">
         <PDBx:U11>0.31833</PDBx:U11>
         <PDBx:U12>0.00407</PDBx:U12>
         <PDBx:U13>-0.00111</PDBx:U13>
         <PDBx:U22>0.36458</PDBx:U22>
         <PDBx:U23>-0.00829</PDBx:U23>
         <PDBx:U33>0.44011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1561">
         <PDBx:U11>0.36781</PDBx:U11>
         <PDBx:U12>-0.00788</PDBx:U12>
         <PDBx:U13>-0.01185</PDBx:U13>
         <PDBx:U22>0.41708</PDBx:U22>
         <PDBx:U23>-0.01459</PDBx:U23>
         <PDBx:U33>0.49817</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1562">
         <PDBx:U11>0.36147</PDBx:U11>
         <PDBx:U12>-0.01550</PDBx:U12>
         <PDBx:U13>-0.01963</PDBx:U13>
         <PDBx:U22>0.38818</PDBx:U22>
         <PDBx:U23>-0.02186</PDBx:U23>
         <PDBx:U33>0.47299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1563">
         <PDBx:U11>0.28044</PDBx:U11>
         <PDBx:U12>0.00120</PDBx:U12>
         <PDBx:U13>0.01571</PDBx:U13>
         <PDBx:U22>0.32046</PDBx:U22>
         <PDBx:U23>-0.00095</PDBx:U23>
         <PDBx:U33>0.40996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1564">
         <PDBx:U11>0.37551</PDBx:U11>
         <PDBx:U12>0.01087</PDBx:U12>
         <PDBx:U13>0.02516</PDBx:U13>
         <PDBx:U22>0.40601</PDBx:U22>
         <PDBx:U23>0.00415</PDBx:U23>
         <PDBx:U33>0.49372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1565">
         <PDBx:U11>0.36552</PDBx:U11>
         <PDBx:U12>0.01900</PDBx:U12>
         <PDBx:U13>0.01958</PDBx:U13>
         <PDBx:U22>0.39545</PDBx:U22>
         <PDBx:U23>0.00194</PDBx:U23>
         <PDBx:U33>0.47042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1566">
         <PDBx:U11>0.40831</PDBx:U11>
         <PDBx:U12>0.00994</PDBx:U12>
         <PDBx:U13>0.03765</PDBx:U13>
         <PDBx:U22>0.43118</PDBx:U22>
         <PDBx:U23>0.01051</PDBx:U23>
         <PDBx:U33>0.53152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1567">
         <PDBx:U11>0.30937</PDBx:U11>
         <PDBx:U12>-0.01070</PDBx:U12>
         <PDBx:U13>-0.01204</PDBx:U13>
         <PDBx:U22>0.38633</PDBx:U22>
         <PDBx:U23>-0.01211</PDBx:U23>
         <PDBx:U33>0.46782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1568">
         <PDBx:U11>0.30965</PDBx:U11>
         <PDBx:U12>-0.01064</PDBx:U12>
         <PDBx:U13>-0.01189</PDBx:U13>
         <PDBx:U22>0.38664</PDBx:U22>
         <PDBx:U23>-0.01203</PDBx:U23>
         <PDBx:U33>0.46814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1569">
         <PDBx:U11>0.39967</PDBx:U11>
         <PDBx:U12>-0.02355</PDBx:U12>
         <PDBx:U13>-0.02210</PDBx:U13>
         <PDBx:U22>0.48249</PDBx:U22>
         <PDBx:U23>-0.01789</PDBx:U23>
         <PDBx:U33>0.57084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1570">
         <PDBx:U11>0.39913</PDBx:U11>
         <PDBx:U12>-0.02320</PDBx:U12>
         <PDBx:U13>-0.02184</PDBx:U13>
         <PDBx:U22>0.48345</PDBx:U22>
         <PDBx:U23>-0.01759</PDBx:U23>
         <PDBx:U33>0.57148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1571">
         <PDBx:U11>0.36765</PDBx:U11>
         <PDBx:U12>-0.01958</PDBx:U12>
         <PDBx:U13>-0.04197</PDBx:U13>
         <PDBx:U22>0.46576</PDBx:U22>
         <PDBx:U23>-0.02422</PDBx:U23>
         <PDBx:U33>0.54189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1572">
         <PDBx:U11>0.36338</PDBx:U11>
         <PDBx:U12>-0.01857</PDBx:U12>
         <PDBx:U13>-0.04106</PDBx:U13>
         <PDBx:U22>0.46592</PDBx:U22>
         <PDBx:U23>-0.02343</PDBx:U23>
         <PDBx:U33>0.54132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1573">
         <PDBx:U11>0.38444</PDBx:U11>
         <PDBx:U12>-0.02913</PDBx:U12>
         <PDBx:U13>-0.05297</PDBx:U13>
         <PDBx:U22>0.49356</PDBx:U22>
         <PDBx:U23>-0.02901</PDBx:U23>
         <PDBx:U33>0.57356</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1574">
         <PDBx:U11>0.37994</PDBx:U11>
         <PDBx:U12>-0.02655</PDBx:U12>
         <PDBx:U13>-0.05045</PDBx:U13>
         <PDBx:U22>0.50049</PDBx:U22>
         <PDBx:U23>-0.02702</PDBx:U23>
         <PDBx:U33>0.57881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1575">
         <PDBx:U11>0.43742</PDBx:U11>
         <PDBx:U12>-0.03088</PDBx:U12>
         <PDBx:U13>-0.01257</PDBx:U13>
         <PDBx:U22>0.54314</PDBx:U22>
         <PDBx:U23>-0.01249</PDBx:U23>
         <PDBx:U33>0.63964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1576">
         <PDBx:U11>0.43621</PDBx:U11>
         <PDBx:U12>-0.03052</PDBx:U12>
         <PDBx:U13>-0.01132</PDBx:U13>
         <PDBx:U22>0.54167</PDBx:U22>
         <PDBx:U23>-0.01186</PDBx:U23>
         <PDBx:U33>0.63837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1577">
         <PDBx:U11>0.42786</PDBx:U11>
         <PDBx:U12>-0.01989</PDBx:U12>
         <PDBx:U13>-0.00823</PDBx:U13>
         <PDBx:U22>0.56856</PDBx:U22>
         <PDBx:U23>-0.00678</PDBx:U23>
         <PDBx:U33>0.65156</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1578">
         <PDBx:U11>0.47578</PDBx:U11>
         <PDBx:U12>-0.03743</PDBx:U12>
         <PDBx:U13>0.00502</PDBx:U13>
         <PDBx:U22>0.55791</PDBx:U22>
         <PDBx:U23>-0.00641</PDBx:U23>
         <PDBx:U33>0.67184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1579">
         <PDBx:U11>0.38734</PDBx:U11>
         <PDBx:U12>-0.00634</PDBx:U12>
         <PDBx:U13>-0.01450</PDBx:U13>
         <PDBx:U22>0.53604</PDBx:U22>
         <PDBx:U23>-0.00803</PDBx:U23>
         <PDBx:U33>0.60429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1613">
         <PDBx:U11>0.42423</PDBx:U11>
         <PDBx:U12>-0.00224</PDBx:U12>
         <PDBx:U13>-0.06142</PDBx:U13>
         <PDBx:U22>0.38378</PDBx:U22>
         <PDBx:U23>-0.03821</PDBx:U23>
         <PDBx:U33>0.42608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1614">
         <PDBx:U11>0.35543</PDBx:U11>
         <PDBx:U12>-0.00038</PDBx:U12>
         <PDBx:U13>-0.05673</PDBx:U13>
         <PDBx:U22>0.35358</PDBx:U22>
         <PDBx:U23>-0.03356</PDBx:U23>
         <PDBx:U33>0.40293</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1615">
         <PDBx:U11>0.39949</PDBx:U11>
         <PDBx:U12>-0.00706</PDBx:U12>
         <PDBx:U13>-0.05758</PDBx:U13>
         <PDBx:U22>0.37869</PDBx:U22>
         <PDBx:U23>-0.03705</PDBx:U23>
         <PDBx:U33>0.43065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1616">
         <PDBx:U11>0.36487</PDBx:U11>
         <PDBx:U12>0.00652</PDBx:U12>
         <PDBx:U13>-0.04219</PDBx:U13>
         <PDBx:U22>0.33205</PDBx:U22>
         <PDBx:U23>-0.03121</PDBx:U23>
         <PDBx:U33>0.37729</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1617">
         <PDBx:U11>0.38012</PDBx:U11>
         <PDBx:U12>0.00325</PDBx:U12>
         <PDBx:U13>-0.04484</PDBx:U13>
         <PDBx:U22>0.33526</PDBx:U22>
         <PDBx:U23>-0.03379</PDBx:U23>
         <PDBx:U33>0.37985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1618">
         <PDBx:U11>0.32083</PDBx:U11>
         <PDBx:U12>0.00427</PDBx:U12>
         <PDBx:U13>-0.04020</PDBx:U13>
         <PDBx:U22>0.32866</PDBx:U22>
         <PDBx:U23>-0.02726</PDBx:U23>
         <PDBx:U33>0.38264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1619">
         <PDBx:U11>0.35538</PDBx:U11>
         <PDBx:U12>-0.00429</PDBx:U12>
         <PDBx:U13>-0.03958</PDBx:U13>
         <PDBx:U22>0.33933</PDBx:U22>
         <PDBx:U23>-0.03151</PDBx:U23>
         <PDBx:U33>0.39888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1620">
         <PDBx:U11>0.37902</PDBx:U11>
         <PDBx:U12>0.00895</PDBx:U12>
         <PDBx:U13>-0.03203</PDBx:U13>
         <PDBx:U22>0.36901</PDBx:U22>
         <PDBx:U23>-0.02576</PDBx:U23>
         <PDBx:U33>0.42076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1621">
         <PDBx:U11>0.36539</PDBx:U11>
         <PDBx:U12>0.00234</PDBx:U12>
         <PDBx:U13>-0.03221</PDBx:U13>
         <PDBx:U22>0.33571</PDBx:U22>
         <PDBx:U23>-0.02959</PDBx:U23>
         <PDBx:U33>0.39096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1622">
         <PDBx:U11>0.62234</PDBx:U11>
         <PDBx:U12>0.01009</PDBx:U12>
         <PDBx:U13>-0.12423</PDBx:U13>
         <PDBx:U22>0.56814</PDBx:U22>
         <PDBx:U23>-0.04424</PDBx:U23>
         <PDBx:U33>0.57798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1623">
         <PDBx:U11>0.56098</PDBx:U11>
         <PDBx:U12>0.02033</PDBx:U12>
         <PDBx:U13>-0.12588</PDBx:U13>
         <PDBx:U22>0.53007</PDBx:U22>
         <PDBx:U23>-0.04149</PDBx:U23>
         <PDBx:U33>0.53946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1624">
         <PDBx:U11>0.70799</PDBx:U11>
         <PDBx:U12>0.00803</PDBx:U12>
         <PDBx:U13>-0.14146</PDBx:U13>
         <PDBx:U22>0.62705</PDBx:U22>
         <PDBx:U23>-0.04644</PDBx:U23>
         <PDBx:U33>0.62774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1625">
         <PDBx:U11>0.67038</PDBx:U11>
         <PDBx:U12>0.02427</PDBx:U12>
         <PDBx:U13>-0.14495</PDBx:U13>
         <PDBx:U22>0.62125</PDBx:U22>
         <PDBx:U23>-0.04237</PDBx:U23>
         <PDBx:U33>0.62218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1626">
         <PDBx:U11>0.75832</PDBx:U11>
         <PDBx:U12>-0.00217</PDBx:U12>
         <PDBx:U13>-0.13011</PDBx:U13>
         <PDBx:U22>0.63977</PDBx:U22>
         <PDBx:U23>-0.04855</PDBx:U23>
         <PDBx:U33>0.63775</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1627">
         <PDBx:U11>0.71473</PDBx:U11>
         <PDBx:U12>0.01479</PDBx:U12>
         <PDBx:U13>-0.14106</PDBx:U13>
         <PDBx:U22>0.62485</PDBx:U22>
         <PDBx:U23>-0.04386</PDBx:U23>
         <PDBx:U33>0.62099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1628">
         <PDBx:U11>0.67592</PDBx:U11>
         <PDBx:U12>0.00105</PDBx:U12>
         <PDBx:U13>-0.11369</PDBx:U13>
         <PDBx:U22>0.54888</PDBx:U22>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1645">
         <PDBx:U11>0.98766</PDBx:U11>
         <PDBx:U12>-0.00557</PDBx:U12>
         <PDBx:U13>-0.19416</PDBx:U13>
         <PDBx:U22>0.85352</PDBx:U22>
         <PDBx:U23>-0.05214</PDBx:U23>
         <PDBx:U33>0.83351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1646">
         <PDBx:U11>0.93068</PDBx:U11>
         <PDBx:U12>-0.04074</PDBx:U12>
         <PDBx:U13>-0.16287</PDBx:U13>
         <PDBx:U22>0.74647</PDBx:U22>
         <PDBx:U23>-0.06587</PDBx:U23>
         <PDBx:U33>0.73092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1647">
         <PDBx:U11>0.95549</PDBx:U11>
         <PDBx:U12>-0.02542</PDBx:U12>
         <PDBx:U13>-0.17082</PDBx:U13>
         <PDBx:U22>0.76319</PDBx:U22>
         <PDBx:U23>-0.05621</PDBx:U23>
         <PDBx:U33>0.73567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1648">
         <PDBx:U11>0.89052</PDBx:U11>
         <PDBx:U12>-0.01032</PDBx:U12>
         <PDBx:U13>-0.15915</PDBx:U13>
         <PDBx:U22>0.70177</PDBx:U22>
         <PDBx:U23>-0.05031</PDBx:U23>
         <PDBx:U33>0.67484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1649">
         <PDBx:U11>0.73110</PDBx:U11>
         <PDBx:U12>0.01468</PDBx:U12>
         <PDBx:U13>-0.14695</PDBx:U13>
         <PDBx:U22>0.57371</PDBx:U22>
         <PDBx:U23>-0.04096</PDBx:U23>
         <PDBx:U33>0.55262</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1650">
         <PDBx:U11>0.88100</PDBx:U11>
         <PDBx:U12>-0.00264</PDBx:U12>
         <PDBx:U13>-0.16046</PDBx:U13>
         <PDBx:U22>0.68053</PDBx:U22>
         <PDBx:U23>-0.04314</PDBx:U23>
         <PDBx:U33>0.64946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1651">
         <PDBx:U11>0.66363</PDBx:U11>
         <PDBx:U12>0.01781</PDBx:U12>
         <PDBx:U13>-0.13650</PDBx:U13>
         <PDBx:U22>0.48841</PDBx:U22>
         <PDBx:U23>-0.03757</PDBx:U23>
         <PDBx:U33>0.46423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1652">
         <PDBx:U11>0.77666</PDBx:U11>
         <PDBx:U12>0.01177</PDBx:U12>
         <PDBx:U13>-0.15833</PDBx:U13>
         <PDBx:U22>0.59638</PDBx:U22>
         <PDBx:U23>-0.04002</PDBx:U23>
         <PDBx:U33>0.56906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1653">
         <PDBx:U11>0.58351</PDBx:U11>
         <PDBx:U12>0.03138</PDBx:U12>
         <PDBx:U13>-0.12990</PDBx:U13>
         <PDBx:U22>0.43571</PDBx:U22>
         <PDBx:U23>-0.03399</PDBx:U23>
         <PDBx:U33>0.41666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1654">
         <PDBx:U11>0.76763</PDBx:U11>
         <PDBx:U12>0.02091</PDBx:U12>
         <PDBx:U13>-0.16716</PDBx:U13>
         <PDBx:U22>0.61799</PDBx:U22>
         <PDBx:U23>-0.04022</PDBx:U23>
         <PDBx:U33>0.59503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1655">
         <PDBx:U11>0.66882</PDBx:U11>
         <PDBx:U12>0.04257</PDBx:U12>
         <PDBx:U13>-0.14410</PDBx:U13>
         <PDBx:U22>0.53793</PDBx:U22>
         <PDBx:U23>-0.03277</PDBx:U23>
         <PDBx:U33>0.51951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1656">
         <PDBx:U11>0.95567</PDBx:U11>
         <PDBx:U12>-0.00049</PDBx:U12>
         <PDBx:U13>-0.17908</PDBx:U13>
         <PDBx:U22>0.75378</PDBx:U22>
         <PDBx:U23>-0.03979</PDBx:U23>
         <PDBx:U33>0.72111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1657">
         <PDBx:U11>0.68513</PDBx:U11>
         <PDBx:U12>0.01778</PDBx:U12>
         <PDBx:U13>-0.14717</PDBx:U13>
         <PDBx:U22>0.48532</PDBx:U22>
         <PDBx:U23>-0.03369</PDBx:U23>
         <PDBx:U33>0.45678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1658">
         <PDBx:U11>0.94305</PDBx:U11>
         <PDBx:U12>0.00811</PDBx:U12>
         <PDBx:U13>-0.18242</PDBx:U13>
         <PDBx:U22>0.72823</PDBx:U22>
         <PDBx:U23>-0.03301</PDBx:U23>
         <PDBx:U33>0.69647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1659">
         <PDBx:U11>0.67493</PDBx:U11>
         <PDBx:U12>0.02136</PDBx:U12>
         <PDBx:U13>-0.13707</PDBx:U13>
         <PDBx:U22>0.46078</PDBx:U22>
         <PDBx:U23>-0.02921</PDBx:U23>
         <PDBx:U33>0.43257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1660">
         <PDBx:U11>0.95042</PDBx:U11>
         <PDBx:U12>0.00112</PDBx:U12>
         <PDBx:U13>-0.16692</PDBx:U13>
         <PDBx:U22>0.70459</PDBx:U22>
         <PDBx:U23>-0.03061</PDBx:U23>
         <PDBx:U33>0.66869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1661">
         <PDBx:U11>0.69518</PDBx:U11>
         <PDBx:U12>0.01231</PDBx:U12>
         <PDBx:U13>-0.11648</PDBx:U13>
         <PDBx:U22>0.46772</PDBx:U22>
         <PDBx:U23>-0.03159</PDBx:U23>
         <PDBx:U33>0.43631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1662">
         <PDBx:U11>0.92359</PDBx:U11>
         <PDBx:U12>0.00919</PDBx:U12>
         <PDBx:U13>-0.20102</PDBx:U13>
         <PDBx:U22>0.70386</PDBx:U22>
         <PDBx:U23>-0.03079</PDBx:U23>
         <PDBx:U33>0.67193</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1663">
         <PDBx:U11>0.70001</PDBx:U11>
         <PDBx:U12>0.01976</PDBx:U12>
         <PDBx:U13>-0.14436</PDBx:U13>
         <PDBx:U22>0.46151</PDBx:U22>
         <PDBx:U23>-0.02444</PDBx:U23>
         <PDBx:U33>0.43433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1664">
         <PDBx:U11>0.72471</PDBx:U11>
         <PDBx:U12>0.01349</PDBx:U12>
         <PDBx:U13>-0.14540</PDBx:U13>
         <PDBx:U22>0.52924</PDBx:U22>
         <PDBx:U23>-0.03712</PDBx:U23>
         <PDBx:U33>0.50029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1665">
         <PDBx:U11>0.56249</PDBx:U11>
         <PDBx:U12>0.03081</PDBx:U12>
         <PDBx:U13>-0.10879</PDBx:U13>
         <PDBx:U22>0.41883</PDBx:U22>
         <PDBx:U23>-0.03262</PDBx:U23>
         <PDBx:U33>0.40324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1666">
         <PDBx:U11>0.66020</PDBx:U11>
         <PDBx:U12>0.02601</PDBx:U12>
         <PDBx:U13>-0.14012</PDBx:U13>
         <PDBx:U22>0.48274</PDBx:U22>
         <PDBx:U23>-0.03428</PDBx:U23>
         <PDBx:U33>0.45698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1667">
         <PDBx:U11>0.48137</PDBx:U11>
         <PDBx:U12>0.04262</PDBx:U12>
         <PDBx:U13>-0.10238</PDBx:U13>
         <PDBx:U22>0.36100</PDBx:U22>
         <PDBx:U23>-0.02937</PDBx:U23>
         <PDBx:U33>0.34802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1668">
         <PDBx:U11>0.64879</PDBx:U11>
         <PDBx:U12>0.03187</PDBx:U12>
         <PDBx:U13>-0.14342</PDBx:U13>
         <PDBx:U22>0.45671</PDBx:U22>
         <PDBx:U23>-0.02882</PDBx:U23>
         <PDBx:U33>0.43214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1669">
         <PDBx:U11>0.55198</PDBx:U11>
         <PDBx:U12>0.04310</PDBx:U12>
         <PDBx:U13>-0.09328</PDBx:U13>
         <PDBx:U22>0.41402</PDBx:U22>
         <PDBx:U23>-0.02700</PDBx:U23>
         <PDBx:U33>0.39867</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1670">
         <PDBx:U11>0.63279</PDBx:U11>
         <PDBx:U12>0.02398</PDBx:U12>
         <PDBx:U13>-0.13865</PDBx:U13>
         <PDBx:U22>0.41234</PDBx:U22>
         <PDBx:U23>-0.02656</PDBx:U23>
         <PDBx:U33>0.38561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1671">
         <PDBx:U11>0.60123</PDBx:U11>
         <PDBx:U12>0.03400</PDBx:U12>
         <PDBx:U13>-0.09052</PDBx:U13>
         <PDBx:U22>0.43420</PDBx:U22>
         <PDBx:U23>-0.02763</PDBx:U23>
         <PDBx:U33>0.41544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1672">
         <PDBx:U11>0.60551</PDBx:U11>
         <PDBx:U12>0.02245</PDBx:U12>
         <PDBx:U13>-0.11396</PDBx:U13>
         <PDBx:U22>0.43280</PDBx:U22>
         <PDBx:U23>-0.03416</PDBx:U23>
         <PDBx:U33>0.41175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1673">
         <PDBx:U11>0.43050</PDBx:U11>
         <PDBx:U12>0.04313</PDBx:U12>
         <PDBx:U13>-0.08751</PDBx:U13>
         <PDBx:U22>0.33807</PDBx:U22>
         <PDBx:U23>-0.02878</PDBx:U23>
         <PDBx:U33>0.33158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1674">
         <PDBx:U11>0.55069</PDBx:U11>
         <PDBx:U12>0.03475</PDBx:U12>
         <PDBx:U13>-0.10676</PDBx:U13>
         <PDBx:U22>0.40210</PDBx:U22>
         <PDBx:U23>-0.03059</PDBx:U23>
         <PDBx:U33>0.38500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1675">
         <PDBx:U11>0.28099</PDBx:U11>
         <PDBx:U12>0.04348</PDBx:U12>
         <PDBx:U13>-0.09748</PDBx:U13>
         <PDBx:U22>0.20965</PDBx:U22>
         <PDBx:U23>-0.03067</PDBx:U23>
         <PDBx:U33>0.20583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1676">
         <PDBx:U11>0.63451</PDBx:U11>
         <PDBx:U12>0.01482</PDBx:U12>
         <PDBx:U13>-0.10473</PDBx:U13>
         <PDBx:U22>0.47399</PDBx:U22>
         <PDBx:U23>-0.03772</PDBx:U23>
         <PDBx:U33>0.45921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1677">
         <PDBx:U11>0.28731</PDBx:U11>
         <PDBx:U12>0.03254</PDBx:U12>
         <PDBx:U13>-0.06867</PDBx:U13>
         <PDBx:U22>0.18209</PDBx:U22>
         <PDBx:U23>-0.02954</PDBx:U23>
         <PDBx:U33>0.18041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1678">
         <PDBx:U11>0.59696</PDBx:U11>
         <PDBx:U12>0.04504</PDBx:U12>
         <PDBx:U13>-0.14955</PDBx:U13>
         <PDBx:U22>0.42461</PDBx:U22>
         <PDBx:U23>-0.02705</PDBx:U23>
         <PDBx:U33>0.40561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1679">
         <PDBx:U11>0.62814</PDBx:U11>
         <PDBx:U12>0.05030</PDBx:U12>
         <PDBx:U13>-0.15326</PDBx:U13>
         <PDBx:U22>0.44121</PDBx:U22>
         <PDBx:U23>-0.02367</PDBx:U23>
         <PDBx:U33>0.42742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1680">
         <PDBx:U11>0.62190</PDBx:U11>
         <PDBx:U12>0.06387</PDBx:U12>
         <PDBx:U13>-0.16037</PDBx:U13>
         <PDBx:U22>0.46057</PDBx:U22>
         <PDBx:U23>-0.02459</PDBx:U23>
         <PDBx:U33>0.45356</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1681">
         <PDBx:U11>0.68241</PDBx:U11>
         <PDBx:U12>0.07026</PDBx:U12>
         <PDBx:U13>-0.15112</PDBx:U13>
         <PDBx:U22>0.54941</PDBx:U22>
         <PDBx:U23>-0.02610</PDBx:U23>
         <PDBx:U33>0.54157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1682">
         <PDBx:U11>0.67571</PDBx:U11>
         <PDBx:U12>0.04869</PDBx:U12>
         <PDBx:U13>-0.14010</PDBx:U13>
         <PDBx:U22>0.47270</PDBx:U22>
         <PDBx:U23>-0.02154</PDBx:U23>
         <PDBx:U33>0.45837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1683">
         <PDBx:U11>0.60285</PDBx:U11>
         <PDBx:U12>0.04154</PDBx:U12>
         <PDBx:U13>-0.12746</PDBx:U13>
         <PDBx:U22>0.39521</PDBx:U22>
         <PDBx:U23>-0.02227</PDBx:U23>
         <PDBx:U33>0.37513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1684">
         <PDBx:U11>0.73555</PDBx:U11>
         <PDBx:U12>0.08179</PDBx:U12>
         <PDBx:U13>-0.15602</PDBx:U13>
         <PDBx:U22>0.63342</PDBx:U22>
         <PDBx:U23>-0.02796</PDBx:U23>
         <PDBx:U33>0.63074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>P</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>P</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>P</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1685">
         <PDBx:U11>0.69609</PDBx:U11>
         <PDBx:U12>0.07921</PDBx:U12>
         <PDBx:U13>-0.16868</PDBx:U13>
         <PDBx:U22>0.60789</PDBx:U22>
         <PDBx:U23>-0.02939</PDBx:U23>
         <PDBx:U33>0.60556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O1P</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O1P</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1686">
         <PDBx:U11>0.73388</PDBx:U11>
         <PDBx:U12>0.08795</PDBx:U12>
         <PDBx:U13>-0.14249</PDBx:U13>
         <PDBx:U22>0.66264</PDBx:U22>
         <PDBx:U23>-0.02881</PDBx:U23>
         <PDBx:U33>0.65817</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O2P</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O2P</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1687">
         <PDBx:U11>0.71098</PDBx:U11>
         <PDBx:U12>0.08827</PDBx:U12>
         <PDBx:U13>-0.16109</PDBx:U13>
         <PDBx:U22>0.59336</PDBx:U22>
         <PDBx:U23>-0.02767</PDBx:U23>
         <PDBx:U33>0.59686</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O3P</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SEP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O3P</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SEP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1688">
         <PDBx:U11>0.44959</PDBx:U11>
         <PDBx:U12>0.05312</PDBx:U12>
         <PDBx:U13>-0.08894</PDBx:U13>
         <PDBx:U22>0.32922</PDBx:U22>
         <PDBx:U23>-0.02460</PDBx:U23>
         <PDBx:U33>0.31492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1689">
         <PDBx:U11>0.48795</PDBx:U11>
         <PDBx:U12>0.05359</PDBx:U12>
         <PDBx:U13>-0.07921</PDBx:U13>
         <PDBx:U22>0.35777</PDBx:U22>
         <PDBx:U23>-0.02251</PDBx:U23>
         <PDBx:U33>0.34251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1690">
         <PDBx:U11>0.52371</PDBx:U11>
         <PDBx:U12>0.05511</PDBx:U12>
         <PDBx:U13>-0.09178</PDBx:U13>
         <PDBx:U22>0.36766</PDBx:U22>
         <PDBx:U23>-0.02175</PDBx:U23>
         <PDBx:U33>0.34912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1691">
         <PDBx:U11>0.52978</PDBx:U11>
         <PDBx:U12>0.04895</PDBx:U12>
         <PDBx:U13>-0.10162</PDBx:U13>
         <PDBx:U22>0.34937</PDBx:U22>
         <PDBx:U23>-0.02232</PDBx:U23>
         <PDBx:U33>0.32788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1692">
         <PDBx:U11>0.48591</PDBx:U11>
         <PDBx:U12>0.04244</PDBx:U12>
         <PDBx:U13>-0.06095</PDBx:U13>
         <PDBx:U22>0.34474</PDBx:U22>
         <PDBx:U23>-0.02275</PDBx:U23>
         <PDBx:U33>0.33149</PDBx:U33>
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         <PDBx:U22>0.35573</PDBx:U22>
         <PDBx:U23>-0.01866</PDBx:U23>
         <PDBx:U33>0.33583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1709">
         <PDBx:U11>0.49497</PDBx:U11>
         <PDBx:U12>0.06992</PDBx:U12>
         <PDBx:U13>-0.09566</PDBx:U13>
         <PDBx:U22>0.32474</PDBx:U22>
         <PDBx:U23>-0.01904</PDBx:U23>
         <PDBx:U33>0.31058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1710">
         <PDBx:U11>0.39831</PDBx:U11>
         <PDBx:U12>0.08036</PDBx:U12>
         <PDBx:U13>-0.10136</PDBx:U13>
         <PDBx:U22>0.25198</PDBx:U22>
         <PDBx:U23>-0.02192</PDBx:U23>
         <PDBx:U33>0.24167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1711">
         <PDBx:U11>0.51263</PDBx:U11>
         <PDBx:U12>0.06547</PDBx:U12>
         <PDBx:U13>-0.09769</PDBx:U13>
         <PDBx:U22>0.31358</PDBx:U22>
         <PDBx:U23>-0.01804</PDBx:U23>
         <PDBx:U33>0.30502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1712">
         <PDBx:U11>0.56905</PDBx:U11>
         <PDBx:U12>0.04681</PDBx:U12>
         <PDBx:U13>-0.10745</PDBx:U13>
         <PDBx:U22>0.34826</PDBx:U22>
         <PDBx:U23>-0.01778</PDBx:U23>
         <PDBx:U33>0.33239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1713">
         <PDBx:U11>0.55409</PDBx:U11>
         <PDBx:U12>0.03999</PDBx:U12>
         <PDBx:U13>-0.09109</PDBx:U13>
         <PDBx:U22>0.32047</PDBx:U22>
         <PDBx:U23>-0.01617</PDBx:U23>
         <PDBx:U33>0.30207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1714">
         <PDBx:U11>0.54016</PDBx:U11>
         <PDBx:U12>0.04997</PDBx:U12>
         <PDBx:U13>-0.09595</PDBx:U13>
         <PDBx:U22>0.33610</PDBx:U22>
         <PDBx:U23>-0.01862</PDBx:U23>
         <PDBx:U33>0.31603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1715">
         <PDBx:U11>0.58007</PDBx:U11>
         <PDBx:U12>0.02540</PDBx:U12>
         <PDBx:U13>-0.08079</PDBx:U13>
         <PDBx:U22>0.32523</PDBx:U22>
         <PDBx:U23>-0.01577</PDBx:U23>
         <PDBx:U33>0.30290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1716">
         <PDBx:U11>0.55461</PDBx:U11>
         <PDBx:U12>0.04294</PDBx:U12>
         <PDBx:U13>-0.08545</PDBx:U13>
         <PDBx:U22>0.33157</PDBx:U22>
         <PDBx:U23>-0.01675</PDBx:U23>
         <PDBx:U33>0.31149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1717">
         <PDBx:U11>0.55182</PDBx:U11>
         <PDBx:U12>0.01836</PDBx:U12>
         <PDBx:U13>-0.06206</PDBx:U13>
         <PDBx:U22>0.29498</PDBx:U22>
         <PDBx:U23>-0.01660</PDBx:U23>
         <PDBx:U33>0.27009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1718">
         <PDBx:U11>0.54739</PDBx:U11>
         <PDBx:U12>0.03139</PDBx:U12>
         <PDBx:U13>-0.08103</PDBx:U13>
         <PDBx:U22>0.29926</PDBx:U22>
         <PDBx:U23>-0.01511</PDBx:U23>
         <PDBx:U33>0.27919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1719">
         <PDBx:U11>0.51104</PDBx:U11>
         <PDBx:U12>0.00974</PDBx:U12>
         <PDBx:U13>-0.04780</PDBx:U13>
         <PDBx:U22>0.25226</PDBx:U22>
         <PDBx:U23>-0.01947</PDBx:U23>
         <PDBx:U33>0.22493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1720">
         <PDBx:U11>0.52729</PDBx:U11>
         <PDBx:U12>0.04446</PDBx:U12>
         <PDBx:U13>-0.08301</PDBx:U13>
         <PDBx:U22>0.33976</PDBx:U22>
         <PDBx:U23>-0.02061</PDBx:U23>
         <PDBx:U33>0.31892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1721">
         <PDBx:U11>0.64507</PDBx:U11>
         <PDBx:U12>0.01959</PDBx:U12>
         <PDBx:U13>-0.08887</PDBx:U13>
         <PDBx:U22>0.36147</PDBx:U22>
         <PDBx:U23>-0.01203</PDBx:U23>
         <PDBx:U33>0.34302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1722">
         <PDBx:U11>0.55018</PDBx:U11>
         <PDBx:U12>0.05402</PDBx:U12>
         <PDBx:U13>-0.08093</PDBx:U13>
         <PDBx:U22>0.39971</PDBx:U22>
         <PDBx:U23>-0.02107</PDBx:U23>
         <PDBx:U33>0.38216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1723">
         <PDBx:U11>0.69289</PDBx:U11>
         <PDBx:U12>0.02651</PDBx:U12>
         <PDBx:U13>-0.10693</PDBx:U13>
         <PDBx:U22>0.41197</PDBx:U22>
         <PDBx:U23>-0.01236</PDBx:U23>
         <PDBx:U33>0.39736</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1724">
         <PDBx:U11>0.51618</PDBx:U11>
         <PDBx:U12>0.06057</PDBx:U12>
         <PDBx:U13>-0.09824</PDBx:U13>
         <PDBx:U22>0.37536</PDBx:U22>
         <PDBx:U23>-0.02248</PDBx:U23>
         <PDBx:U33>0.35773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1725">
         <PDBx:U11>0.82351</PDBx:U11>
         <PDBx:U12>0.01732</PDBx:U12>
         <PDBx:U13>-0.11271</PDBx:U13>
         <PDBx:U22>0.51531</PDBx:U22>
         <PDBx:U23>-0.01000</PDBx:U23>
         <PDBx:U33>0.50003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1726">
         <PDBx:U11>0.44354</PDBx:U11>
         <PDBx:U12>0.06552</PDBx:U12>
         <PDBx:U13>-0.09457</PDBx:U13>
         <PDBx:U22>0.33622</PDBx:U22>
         <PDBx:U23>-0.02324</PDBx:U23>
         <PDBx:U33>0.32119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1727">
         <PDBx:U11>0.82503</PDBx:U11>
         <PDBx:U12>0.02341</PDBx:U12>
         <PDBx:U13>-0.12950</PDBx:U13>
         <PDBx:U22>0.52418</PDBx:U22>
         <PDBx:U23>-0.01117</PDBx:U23>
         <PDBx:U33>0.51102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1728">
         <PDBx:U11>0.42534</PDBx:U11>
         <PDBx:U12>0.07152</PDBx:U12>
         <PDBx:U13>-0.10796</PDBx:U13>
         <PDBx:U22>0.33337</PDBx:U22>
         <PDBx:U23>-0.02477</PDBx:U23>
         <PDBx:U33>0.31903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1729">
         <PDBx:U11>0.89088</PDBx:U11>
         <PDBx:U12>0.01753</PDBx:U12>
         <PDBx:U13>-0.13847</PDBx:U13>
         <PDBx:U22>0.57102</PDBx:U22>
         <PDBx:U23>-0.00962</PDBx:U23>
         <PDBx:U33>0.55648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1730">
         <PDBx:U11>0.52365</PDBx:U11>
         <PDBx:U12>0.07390</PDBx:U12>
         <PDBx:U13>-0.12548</PDBx:U13>
         <PDBx:U22>0.41665</PDBx:U22>
         <PDBx:U23>-0.02552</PDBx:U23>
         <PDBx:U33>0.40177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1731">
         <PDBx:U11>0.94425</PDBx:U11>
         <PDBx:U12>0.00526</PDBx:U12>
         <PDBx:U13>-0.13153</PDBx:U13>
         <PDBx:U22>0.59556</PDBx:U22>
         <PDBx:U23>-0.00678</PDBx:U23>
         <PDBx:U33>0.57730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1732">
         <PDBx:U11>0.30820</PDBx:U11>
         <PDBx:U12>0.07435</PDBx:U12>
         <PDBx:U13>-0.10320</PDBx:U13>
         <PDBx:U22>0.24654</PDBx:U22>
         <PDBx:U23>-0.02523</PDBx:U23>
         <PDBx:U33>0.23440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1733">
         <PDBx:U11>0.87476</PDBx:U11>
         <PDBx:U12>0.02365</PDBx:U12>
         <PDBx:U13>-0.15418</PDBx:U13>
         <PDBx:U22>0.56566</PDBx:U22>
         <PDBx:U23>-0.01097</PDBx:U23>
         <PDBx:U33>0.55295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1734">
         <PDBx:U11>0.46580</PDBx:U11>
         <PDBx:U12>0.04928</PDBx:U12>
         <PDBx:U13>-0.08043</PDBx:U13>
         <PDBx:U22>0.25755</PDBx:U22>
         <PDBx:U23>-0.01659</PDBx:U23>
         <PDBx:U33>0.23860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1735">
         <PDBx:U11>0.53213</PDBx:U11>
         <PDBx:U12>0.02176</PDBx:U12>
         <PDBx:U13>-0.06097</PDBx:U13>
         <PDBx:U22>0.27620</PDBx:U22>
         <PDBx:U23>-0.01501</PDBx:U23>
         <PDBx:U33>0.25360</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1736">
         <PDBx:U11>0.46519</PDBx:U11>
         <PDBx:U12>0.04194</PDBx:U12>
         <PDBx:U13>-0.06970</PDBx:U13>
         <PDBx:U22>0.24447</PDBx:U22>
         <PDBx:U23>-0.01534</PDBx:U23>
         <PDBx:U33>0.22626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1737">
         <PDBx:U11>0.56055</PDBx:U11>
         <PDBx:U12>0.01380</PDBx:U12>
         <PDBx:U13>-0.04281</PDBx:U13>
         <PDBx:U22>0.30547</PDBx:U22>
         <PDBx:U23>-0.01532</PDBx:U23>
         <PDBx:U33>0.28334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1738">
         <PDBx:U11>0.48517</PDBx:U11>
         <PDBx:U12>0.02953</PDBx:U12>
         <PDBx:U13>-0.05119</PDBx:U13>
         <PDBx:U22>0.26328</PDBx:U22>
         <PDBx:U23>-0.01581</PDBx:U23>
         <PDBx:U33>0.24413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1739">
         <PDBx:U11>0.47026</PDBx:U11>
         <PDBx:U12>0.01573</PDBx:U12>
         <PDBx:U13>-0.02789</PDBx:U13>
         <PDBx:U22>0.24615</PDBx:U22>
         <PDBx:U23>-0.01696</PDBx:U23>
         <PDBx:U33>0.22755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1740">
         <PDBx:U11>0.57274</PDBx:U11>
         <PDBx:U12>0.01857</PDBx:U12>
         <PDBx:U13>-0.04374</PDBx:U13>
         <PDBx:U22>0.32877</PDBx:U22>
         <PDBx:U23>-0.01509</PDBx:U23>
         <PDBx:U33>0.30849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1741">
         <PDBx:U11>0.49860</PDBx:U11>
         <PDBx:U12>0.00861</PDBx:U12>
         <PDBx:U13>-0.01126</PDBx:U13>
         <PDBx:U22>0.27775</PDBx:U22>
         <PDBx:U23>-0.01736</PDBx:U23>
         <PDBx:U33>0.26136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1742">
         <PDBx:U11>0.47481</PDBx:U11>
         <PDBx:U12>0.05055</PDBx:U12>
         <PDBx:U13>-0.06686</PDBx:U13>
         <PDBx:U22>0.27650</PDBx:U22>
         <PDBx:U23>-0.01561</PDBx:U23>
         <PDBx:U33>0.26058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1743">
         <PDBx:U11>0.55577</PDBx:U11>
         <PDBx:U12>0.01733</PDBx:U12>
         <PDBx:U13>-0.04578</PDBx:U13>
         <PDBx:U22>0.30044</PDBx:U22>
         <PDBx:U23>-0.01356</PDBx:U23>
         <PDBx:U33>0.28149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1744">
         <PDBx:U11>0.51636</PDBx:U11>
         <PDBx:U12>0.04364</PDBx:U12>
         <PDBx:U13>-0.06004</PDBx:U13>
         <PDBx:U22>0.30541</PDBx:U22>
         <PDBx:U23>-0.01470</PDBx:U23>
         <PDBx:U33>0.29109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1745">
         <PDBx:U11>0.58608</PDBx:U11>
         <PDBx:U12>0.01320</PDBx:U12>
         <PDBx:U13>-0.05562</PDBx:U13>
         <PDBx:U22>0.29982</PDBx:U22>
         <PDBx:U23>-0.01001</PDBx:U23>
         <PDBx:U33>0.28382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1746">
         <PDBx:U11>0.52236</PDBx:U11>
         <PDBx:U12>0.03591</PDBx:U12>
         <PDBx:U13>-0.06480</PDBx:U13>
         <PDBx:U22>0.27730</PDBx:U22>
         <PDBx:U23>-0.01324</PDBx:U23>
         <PDBx:U33>0.26411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1747">
         <PDBx:U11>0.55336</PDBx:U11>
         <PDBx:U12>0.01285</PDBx:U12>
         <PDBx:U13>-0.06660</PDBx:U13>
         <PDBx:U22>0.24999</PDBx:U22>
         <PDBx:U23>-0.00759</PDBx:U23>
         <PDBx:U33>0.23753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1748">
         <PDBx:U11>0.47717</PDBx:U11>
         <PDBx:U12>0.04261</PDBx:U12>
         <PDBx:U13>-0.04956</PDBx:U13>
         <PDBx:U22>0.28323</PDBx:U22>
         <PDBx:U23>-0.01480</PDBx:U23>
         <PDBx:U33>0.26971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1749">
         <PDBx:U11>0.61558</PDBx:U11>
         <PDBx:U12>0.00887</PDBx:U12>
         <PDBx:U13>-0.05531</PDBx:U13>
         <PDBx:U22>0.31354</PDBx:U22>
         <PDBx:U23>-0.00806</PDBx:U23>
         <PDBx:U33>0.30128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1750">
         <PDBx:U11>0.56732</PDBx:U11>
         <PDBx:U12>0.02952</PDBx:U12>
         <PDBx:U13>-0.05648</PDBx:U13>
         <PDBx:U22>0.31949</PDBx:U22>
         <PDBx:U23>-0.01289</PDBx:U23>
         <PDBx:U33>0.30844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1751">
         <PDBx:U11>0.67066</PDBx:U11>
         <PDBx:U12>0.00940</PDBx:U12>
         <PDBx:U13>-0.07251</PDBx:U13>
         <PDBx:U22>0.34102</PDBx:U22>
         <PDBx:U23>-0.00450</PDBx:U23>
         <PDBx:U33>0.33532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1752">
         <PDBx:U11>0.45724</PDBx:U11>
         <PDBx:U12>0.03368</PDBx:U12>
         <PDBx:U13>-0.04785</PDBx:U13>
         <PDBx:U22>0.24101</PDBx:U22>
         <PDBx:U23>-0.01406</PDBx:U23>
         <PDBx:U33>0.22963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1753">
         <PDBx:U11>0.65130</PDBx:U11>
         <PDBx:U12>0.00652</PDBx:U12>
         <PDBx:U13>-0.06574</PDBx:U13>
         <PDBx:U22>0.32110</PDBx:U22>
         <PDBx:U23>-0.00436</PDBx:U23>
         <PDBx:U33>0.31558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1754">
         <PDBx:U11>0.44091</PDBx:U11>
         <PDBx:U12>0.03108</PDBx:U12>
         <PDBx:U13>-0.04280</PDBx:U13>
         <PDBx:U22>0.24210</PDBx:U22>
         <PDBx:U23>-0.01711</PDBx:U23>
         <PDBx:U33>0.22434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1755">
         <PDBx:U11>0.42914</PDBx:U11>
         <PDBx:U12>0.02516</PDBx:U12>
         <PDBx:U13>-0.03330</PDBx:U13>
         <PDBx:U22>0.22779</PDBx:U22>
         <PDBx:U23>-0.01758</PDBx:U23>
         <PDBx:U33>0.21060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1756">
         <PDBx:U11>0.44304</PDBx:U11>
         <PDBx:U12>0.02130</PDBx:U12>
         <PDBx:U13>-0.02556</PDBx:U13>
         <PDBx:U22>0.24313</PDBx:U22>
         <PDBx:U23>-0.01847</PDBx:U23>
         <PDBx:U33>0.22688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1757">
         <PDBx:U11>0.40548</PDBx:U11>
         <PDBx:U12>0.02830</PDBx:U12>
         <PDBx:U13>-0.02088</PDBx:U13>
         <PDBx:U22>0.23256</PDBx:U22>
         <PDBx:U23>-0.01772</PDBx:U23>
         <PDBx:U33>0.21975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1758">
         <PDBx:U11>0.40392</PDBx:U11>
         <PDBx:U12>0.01907</PDBx:U12>
         <PDBx:U13>-0.02847</PDBx:U13>
         <PDBx:U22>0.20117</PDBx:U22>
         <PDBx:U23>-0.02091</PDBx:U23>
         <PDBx:U33>0.18423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1759">
         <PDBx:U11>0.37990</PDBx:U11>
         <PDBx:U12>0.02618</PDBx:U12>
         <PDBx:U13>-0.01891</PDBx:U13>
         <PDBx:U22>0.20970</PDBx:U22>
         <PDBx:U23>-0.01983</PDBx:U23>
         <PDBx:U33>0.19865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1760">
         <PDBx:U11>0.50032</PDBx:U11>
         <PDBx:U12>0.02695</PDBx:U12>
         <PDBx:U13>-0.03769</PDBx:U13>
         <PDBx:U22>0.31473</PDBx:U22>
         <PDBx:U23>-0.02106</PDBx:U23>
         <PDBx:U33>0.29883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1761">
         <PDBx:U11>0.36696</PDBx:U11>
         <PDBx:U12>0.03100</PDBx:U12>
         <PDBx:U13>-0.01394</PDBx:U13>
         <PDBx:U22>0.21984</PDBx:U22>
         <PDBx:U23>-0.01934</PDBx:U23>
         <PDBx:U33>0.21319</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1762">
         <PDBx:U11>0.40860</PDBx:U11>
         <PDBx:U12>0.02485</PDBx:U12>
         <PDBx:U13>-0.01164</PDBx:U13>
         <PDBx:U22>0.23714</PDBx:U22>
         <PDBx:U23>-0.01761</PDBx:U23>
         <PDBx:U33>0.22609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1763">
         <PDBx:U11>0.42228</PDBx:U11>
         <PDBx:U12>0.04060</PDBx:U12>
         <PDBx:U13>-0.02671</PDBx:U13>
         <PDBx:U22>0.27542</PDBx:U22>
         <PDBx:U23>-0.01603</PDBx:U23>
         <PDBx:U33>0.26278</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1764">
         <PDBx:U11>0.35711</PDBx:U11>
         <PDBx:U12>0.02818</PDBx:U12>
         <PDBx:U13>-0.01099</PDBx:U13>
         <PDBx:U22>0.19465</PDBx:U22>
         <PDBx:U23>-0.01564</PDBx:U23>
         <PDBx:U33>0.18377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1765">
         <PDBx:U11>0.39090</PDBx:U11>
         <PDBx:U12>0.04243</PDBx:U12>
         <PDBx:U13>-0.03204</PDBx:U13>
         <PDBx:U22>0.23618</PDBx:U22>
         <PDBx:U23>-0.01522</PDBx:U23>
         <PDBx:U33>0.22192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1766">
         <PDBx:U11>0.42357</PDBx:U11>
         <PDBx:U12>0.02031</PDBx:U12>
         <PDBx:U13>-0.00919</PDBx:U13>
         <PDBx:U22>0.24101</PDBx:U22>
         <PDBx:U23>-0.01536</PDBx:U23>
         <PDBx:U33>0.22918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1767">
         <PDBx:U11>0.39022</PDBx:U11>
         <PDBx:U12>0.04706</PDBx:U12>
         <PDBx:U13>-0.04811</PDBx:U13>
         <PDBx:U22>0.21951</PDBx:U22>
         <PDBx:U23>-0.01562</PDBx:U23>
         <PDBx:U33>0.20361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1768">
         <PDBx:U11>0.39708</PDBx:U11>
         <PDBx:U12>0.03816</PDBx:U12>
         <PDBx:U13>-0.01180</PDBx:U13>
         <PDBx:U22>0.26286</PDBx:U22>
         <PDBx:U23>-0.01412</PDBx:U23>
         <PDBx:U33>0.25262</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1769">
         <PDBx:U11>0.37313</PDBx:U11>
         <PDBx:U12>0.03933</PDBx:U12>
         <PDBx:U13>-0.02163</PDBx:U13>
         <PDBx:U22>0.22593</PDBx:U22>
         <PDBx:U23>-0.01422</PDBx:U23>
         <PDBx:U33>0.21313</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1770">
         <PDBx:U11>0.41659</PDBx:U11>
         <PDBx:U12>0.02225</PDBx:U12>
         <PDBx:U13>-0.00931</PDBx:U13>
         <PDBx:U22>0.24254</PDBx:U22>
         <PDBx:U23>-0.01421</PDBx:U23>
         <PDBx:U33>0.23162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1771">
         <PDBx:U11>0.44306</PDBx:U11>
         <PDBx:U12>0.04825</PDBx:U12>
         <PDBx:U13>-0.05284</PDBx:U13>
         <PDBx:U22>0.26148</PDBx:U22>
         <PDBx:U23>-0.01531</PDBx:U23>
         <PDBx:U33>0.24630</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1772">
         <PDBx:U11>0.36797</PDBx:U11>
         <PDBx:U12>0.04068</PDBx:U12>
         <PDBx:U13>-0.01216</PDBx:U13>
         <PDBx:U22>0.24182</PDBx:U22>
         <PDBx:U23>-0.01306</PDBx:U23>
         <PDBx:U33>0.23060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1773">
         <PDBx:U11>0.39268</PDBx:U11>
         <PDBx:U12>0.03943</PDBx:U12>
         <PDBx:U13>-0.02683</PDBx:U13>
         <PDBx:U22>0.23688</PDBx:U22>
         <PDBx:U23>-0.01411</PDBx:U23>
         <PDBx:U33>0.22345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1774">
         <PDBx:U11>0.37966</PDBx:U11>
         <PDBx:U12>0.03265</PDBx:U12>
         <PDBx:U13>-0.01126</PDBx:U13>
         <PDBx:U22>0.23404</PDBx:U22>
         <PDBx:U23>-0.01342</PDBx:U23>
         <PDBx:U33>0.22310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1775">
         <PDBx:U11>0.42983</PDBx:U11>
         <PDBx:U12>0.04378</PDBx:U12>
         <PDBx:U13>-0.04205</PDBx:U13>
         <PDBx:U22>0.25556</PDBx:U22>
         <PDBx:U23>-0.01480</PDBx:U23>
         <PDBx:U33>0.24135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1776">
         <PDBx:U11>0.42959</PDBx:U11>
         <PDBx:U12>0.03428</PDBx:U12>
         <PDBx:U13>-0.01240</PDBx:U13>
         <PDBx:U22>0.29254</PDBx:U22>
         <PDBx:U23>-0.01300</PDBx:U23>
         <PDBx:U33>0.28119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1777">
         <PDBx:U11>0.48771</PDBx:U11>
         <PDBx:U12>0.04364</PDBx:U12>
         <PDBx:U13>-0.04720</PDBx:U13>
         <PDBx:U22>0.30160</PDBx:U22>
         <PDBx:U23>-0.01509</PDBx:U23>
         <PDBx:U33>0.28885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1778">
         <PDBx:U11>0.44098</PDBx:U11>
         <PDBx:U12>0.00762</PDBx:U12>
         <PDBx:U13>-0.02011</PDBx:U13>
         <PDBx:U22>0.21674</PDBx:U22>
         <PDBx:U23>-0.02334</PDBx:U23>
         <PDBx:U33>0.19779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1779">
         <PDBx:U11>0.44234</PDBx:U11>
         <PDBx:U12>0.01787</PDBx:U12>
         <PDBx:U13>-0.02258</PDBx:U13>
         <PDBx:U22>0.24649</PDBx:U22>
         <PDBx:U23>-0.02210</PDBx:U23>
         <PDBx:U33>0.23187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1780">
         <PDBx:U11>0.48685</PDBx:U11>
         <PDBx:U12>0.00360</PDBx:U12>
         <PDBx:U13>-0.02276</PDBx:U13>
         <PDBx:U22>0.25652</PDBx:U22>
         <PDBx:U23>-0.02675</PDBx:U23>
         <PDBx:U33>0.23660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1781">
         <PDBx:U11>0.40098</PDBx:U11>
         <PDBx:U12>0.01464</PDBx:U12>
         <PDBx:U13>-0.02453</PDBx:U13>
         <PDBx:U22>0.20307</PDBx:U22>
         <PDBx:U23>-0.02510</PDBx:U23>
         <PDBx:U33>0.18910</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1782">
         <PDBx:U11>0.42628</PDBx:U11>
         <PDBx:U12>-0.00222</PDBx:U12>
         <PDBx:U13>-0.00198</PDBx:U13>
         <PDBx:U22>0.20063</PDBx:U22>
         <PDBx:U23>-0.02993</PDBx:U23>
         <PDBx:U33>0.18713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1783">
         <PDBx:U11>0.41991</PDBx:U11>
         <PDBx:U12>0.00497</PDBx:U12>
         <PDBx:U13>-0.00551</PDBx:U13>
         <PDBx:U22>0.21346</PDBx:U22>
         <PDBx:U23>-0.02838</PDBx:U23>
         <PDBx:U33>0.20351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1784">
         <PDBx:U11>0.51873</PDBx:U11>
         <PDBx:U12>-0.01139</PDBx:U12>
         <PDBx:U13>0.01169</PDBx:U13>
         <PDBx:U22>0.27578</PDBx:U22>
         <PDBx:U23>-0.03194</PDBx:U23>
         <PDBx:U33>0.26093</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1785">
         <PDBx:U11>0.45136</PDBx:U11>
         <PDBx:U12>-0.00369</PDBx:U12>
         <PDBx:U13>0.00363</PDBx:U13>
         <PDBx:U22>0.22423</PDBx:U22>
         <PDBx:U23>-0.02962</PDBx:U23>
         <PDBx:U33>0.21118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1786">
         <PDBx:U11>0.48126</PDBx:U11>
         <PDBx:U12>-0.00485</PDBx:U12>
         <PDBx:U13>-0.03333</PDBx:U13>
         <PDBx:U22>0.21719</PDBx:U22>
         <PDBx:U23>-0.02767</PDBx:U23>
         <PDBx:U33>0.18808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1787">
         <PDBx:U11>0.47529</PDBx:U11>
         <PDBx:U12>0.01166</PDBx:U12>
         <PDBx:U13>-0.04235</PDBx:U13>
         <PDBx:U22>0.25357</PDBx:U22>
         <PDBx:U23>-0.02596</PDBx:U23>
         <PDBx:U33>0.23209</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1788">
         <PDBx:U11>0.62825</PDBx:U11>
         <PDBx:U12>0.00193</PDBx:U12>
         <PDBx:U13>-0.05399</PDBx:U13>
         <PDBx:U22>0.36064</PDBx:U22>
         <PDBx:U23>-0.02253</PDBx:U23>
         <PDBx:U33>0.33018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1789">
         <PDBx:U11>0.48602</PDBx:U11>
         <PDBx:U12>0.00734</PDBx:U12>
         <PDBx:U13>-0.04786</PDBx:U13>
         <PDBx:U22>0.26083</PDBx:U22>
         <PDBx:U23>-0.02950</PDBx:U23>
         <PDBx:U33>0.23863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1790">
         <PDBx:U11>0.70227</PDBx:U11>
         <PDBx:U12>-0.00316</PDBx:U12>
         <PDBx:U13>-0.06604</PDBx:U13>
         <PDBx:U22>0.41807</PDBx:U22>
         <PDBx:U23>-0.02084</PDBx:U23>
         <PDBx:U33>0.38548</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1791">
         <PDBx:U11>0.57169</PDBx:U11>
         <PDBx:U12>0.00560</PDBx:U12>
         <PDBx:U13>-0.06836</PDBx:U13>
         <PDBx:U22>0.32426</PDBx:U22>
         <PDBx:U23>-0.02934</PDBx:U23>
         <PDBx:U33>0.29379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1792">
         <PDBx:U11>0.63673</PDBx:U11>
         <PDBx:U12>0.00198</PDBx:U12>
         <PDBx:U13>-0.07827</PDBx:U13>
         <PDBx:U22>0.36771</PDBx:U22>
         <PDBx:U23>-0.02414</PDBx:U23>
         <PDBx:U33>0.33500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1793">
         <PDBx:U11>0.55750</PDBx:U11>
         <PDBx:U12>0.01821</PDBx:U12>
         <PDBx:U13>-0.08598</PDBx:U13>
         <PDBx:U22>0.32431</PDBx:U22>
         <PDBx:U23>-0.02633</PDBx:U23>
         <PDBx:U33>0.29477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1794">
         <PDBx:U11>0.62364</PDBx:U11>
         <PDBx:U12>-0.00335</PDBx:U12>
         <PDBx:U13>-0.08696</PDBx:U13>
         <PDBx:U22>0.34606</PDBx:U22>
         <PDBx:U23>-0.02506</PDBx:U23>
         <PDBx:U33>0.31096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1795">
         <PDBx:U11>0.49062</PDBx:U11>
         <PDBx:U12>0.02044</PDBx:U12>
         <PDBx:U13>-0.09983</PDBx:U13>
         <PDBx:U22>0.24623</PDBx:U22>
         <PDBx:U23>-0.02217</PDBx:U23>
         <PDBx:U33>0.21833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1796">
         <PDBx:U11>0.65449</PDBx:U11>
         <PDBx:U12>0.00084</PDBx:U12>
         <PDBx:U13>-0.09833</PDBx:U13>
         <PDBx:U22>0.39364</PDBx:U22>
         <PDBx:U23>-0.02845</PDBx:U23>
         <PDBx:U33>0.35919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1797">
         <PDBx:U11>0.59486</PDBx:U11>
         <PDBx:U12>0.01053</PDBx:U12>
         <PDBx:U13>-0.09922</PDBx:U13>
         <PDBx:U22>0.32448</PDBx:U22>
         <PDBx:U23>-0.01987</PDBx:U23>
         <PDBx:U33>0.29518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1798">
         <PDBx:U11>0.80916</PDBx:U11>
         <PDBx:U12>-0.01335</PDBx:U12>
         <PDBx:U13>-0.08457</PDBx:U13>
         <PDBx:U22>0.50658</PDBx:U22>
         <PDBx:U23>-0.02278</PDBx:U23>
         <PDBx:U33>0.46809</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1799">
         <PDBx:U11>0.55407</PDBx:U11>
         <PDBx:U12>0.03284</PDBx:U12>
         <PDBx:U13>-0.11253</PDBx:U13>
         <PDBx:U22>0.32459</PDBx:U22>
         <PDBx:U23>-0.02070</PDBx:U23>
         <PDBx:U33>0.30158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1800">
         <PDBx:U11>0.45393</PDBx:U11>
         <PDBx:U12>0.00320</PDBx:U12>
         <PDBx:U13>0.00113</PDBx:U13>
         <PDBx:U22>0.25112</PDBx:U22>
         <PDBx:U23>-0.03031</PDBx:U23>
         <PDBx:U33>0.24547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1801">
         <PDBx:U11>0.38792</PDBx:U11>
         <PDBx:U12>0.00628</PDBx:U12>
         <PDBx:U13>0.00092</PDBx:U13>
         <PDBx:U22>0.19627</PDBx:U22>
         <PDBx:U23>-0.03002</PDBx:U23>
         <PDBx:U33>0.19392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1802">
         <PDBx:U11>0.42208</PDBx:U11>
         <PDBx:U12>-0.00121</PDBx:U12>
         <PDBx:U13>0.01934</PDBx:U13>
         <PDBx:U22>0.22087</PDBx:U22>
         <PDBx:U23>-0.03348</PDBx:U23>
         <PDBx:U33>0.22413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1803">
         <PDBx:U11>0.41749</PDBx:U11>
         <PDBx:U12>-0.00041</PDBx:U12>
         <PDBx:U13>0.01995</PDBx:U13>
         <PDBx:U22>0.21984</PDBx:U22>
         <PDBx:U23>-0.03360</PDBx:U23>
         <PDBx:U33>0.22500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1804">
         <PDBx:U11>0.46460</PDBx:U11>
         <PDBx:U12>-0.01243</PDBx:U12>
         <PDBx:U13>0.02086</PDBx:U13>
         <PDBx:U22>0.23532</PDBx:U22>
         <PDBx:U23>-0.03963</PDBx:U23>
         <PDBx:U33>0.23489</PDBx:U33>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1821">
         <PDBx:U11>0.45110</PDBx:U11>
         <PDBx:U12>-0.02398</PDBx:U12>
         <PDBx:U13>0.03453</PDBx:U13>
         <PDBx:U22>0.22036</PDBx:U22>
         <PDBx:U23>-0.05584</PDBx:U23>
         <PDBx:U33>0.25569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1822">
         <PDBx:U11>0.37960</PDBx:U11>
         <PDBx:U12>-0.01191</PDBx:U12>
         <PDBx:U13>0.02864</PDBx:U13>
         <PDBx:U22>0.18148</PDBx:U22>
         <PDBx:U23>-0.04708</PDBx:U23>
         <PDBx:U33>0.21904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1823">
         <PDBx:U11>0.44183</PDBx:U11>
         <PDBx:U12>-0.00484</PDBx:U12>
         <PDBx:U13>0.04218</PDBx:U13>
         <PDBx:U22>0.25580</PDBx:U22>
         <PDBx:U23>-0.04231</PDBx:U23>
         <PDBx:U33>0.29708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1824">
         <PDBx:U11>0.39908</PDBx:U11>
         <PDBx:U12>-0.00909</PDBx:U12>
         <PDBx:U13>0.05372</PDBx:U13>
         <PDBx:U22>0.19752</PDBx:U22>
         <PDBx:U23>-0.04513</PDBx:U23>
         <PDBx:U33>0.23696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1825">
         <PDBx:U11>0.34292</PDBx:U11>
         <PDBx:U12>0.00452</PDBx:U12>
         <PDBx:U13>0.04090</PDBx:U13>
         <PDBx:U22>0.18279</PDBx:U22>
         <PDBx:U23>-0.03578</PDBx:U23>
         <PDBx:U33>0.22792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1826">
         <PDBx:U11>0.49225</PDBx:U11>
         <PDBx:U12>-0.01915</PDBx:U12>
         <PDBx:U13>-0.00803</PDBx:U13>
         <PDBx:U22>0.25837</PDBx:U22>
         <PDBx:U23>-0.04820</PDBx:U23>
         <PDBx:U33>0.25941</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1827">
         <PDBx:U11>0.50888</PDBx:U11>
         <PDBx:U12>-0.01568</PDBx:U12>
         <PDBx:U13>-0.03176</PDBx:U13>
         <PDBx:U22>0.27812</PDBx:U22>
         <PDBx:U23>-0.04591</PDBx:U23>
         <PDBx:U33>0.27003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1828">
         <PDBx:U11>0.54902</PDBx:U11>
         <PDBx:U12>-0.02431</PDBx:U12>
         <PDBx:U13>-0.04166</PDBx:U13>
         <PDBx:U22>0.28518</PDBx:U22>
         <PDBx:U23>-0.04827</PDBx:U23>
         <PDBx:U33>0.26346</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1829">
         <PDBx:U11>0.59233</PDBx:U11>
         <PDBx:U12>-0.02778</PDBx:U12>
         <PDBx:U13>-0.05835</PDBx:U13>
         <PDBx:U22>0.32281</PDBx:U22>
         <PDBx:U23>-0.04945</PDBx:U23>
         <PDBx:U33>0.29562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1830">
         <PDBx:U11>0.49910</PDBx:U11>
         <PDBx:U12>-0.00324</PDBx:U12>
         <PDBx:U13>-0.03712</PDBx:U13>
         <PDBx:U22>0.29032</PDBx:U22>
         <PDBx:U23>-0.03923</PDBx:U23>
         <PDBx:U33>0.28173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1831">
         <PDBx:U11>0.61260</PDBx:U11>
         <PDBx:U12>0.00144</PDBx:U12>
         <PDBx:U13>-0.06115</PDBx:U13>
         <PDBx:U22>0.40466</PDBx:U22>
         <PDBx:U23>-0.03765</PDBx:U23>
         <PDBx:U33>0.38850</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1832">
         <PDBx:U11>0.44665</PDBx:U11>
         <PDBx:U12>0.00478</PDBx:U12>
         <PDBx:U13>-0.02895</PDBx:U13>
         <PDBx:U22>0.26994</PDBx:U22>
         <PDBx:U23>-0.03642</PDBx:U23>
         <PDBx:U33>0.27200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1833">
         <PDBx:U11>0.63062</PDBx:U11>
         <PDBx:U12>-0.02764</PDBx:U12>
         <PDBx:U13>-0.02970</PDBx:U13>
         <PDBx:U22>0.35362</PDBx:U22>
         <PDBx:U23>-0.04553</PDBx:U23>
         <PDBx:U33>0.32782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1834">
         <PDBx:U11>0.61833</PDBx:U11>
         <PDBx:U12>-0.03513</PDBx:U12>
         <PDBx:U13>-0.03415</PDBx:U13>
         <PDBx:U22>0.32087</PDBx:U22>
         <PDBx:U23>-0.04178</PDBx:U23>
         <PDBx:U33>0.28550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1835">
         <PDBx:U11>0.69976</PDBx:U11>
         <PDBx:U12>-0.04486</PDBx:U12>
         <PDBx:U13>-0.03338</PDBx:U13>
         <PDBx:U22>0.39005</PDBx:U22>
         <PDBx:U23>-0.04635</PDBx:U23>
         <PDBx:U33>0.35208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1836">
         <PDBx:U11>0.69880</PDBx:U11>
         <PDBx:U12>-0.04857</PDBx:U12>
         <PDBx:U13>-0.04799</PDBx:U13>
         <PDBx:U22>0.37687</PDBx:U22>
         <PDBx:U23>-0.04433</PDBx:U23>
         <PDBx:U33>0.33145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1837">
         <PDBx:U11>0.59944</PDBx:U11>
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         <PDBx:U13>-0.01701</PDBx:U13>
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         <PDBx:U23>-0.03871</PDBx:U23>
         <PDBx:U33>0.25511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1838">
         <PDBx:U11>0.60776</PDBx:U11>
         <PDBx:U12>-0.03053</PDBx:U12>
         <PDBx:U13>-0.02045</PDBx:U13>
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         <PDBx:U23>-0.03408</PDBx:U23>
         <PDBx:U33>0.27493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.68008</PDBx:U11>
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         <PDBx:U23>-0.03554</PDBx:U23>
         <PDBx:U33>0.30152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.68294</PDBx:U11>
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         <PDBx:U13>-0.00452</PDBx:U13>
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         <PDBx:U23>-0.03152</PDBx:U23>
         <PDBx:U33>0.34092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.01629</PDBx:U13>
         <PDBx:U22>0.34201</PDBx:U22>
         <PDBx:U23>-0.05251</PDBx:U23>
         <PDBx:U33>0.31142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.01250</PDBx:U13>
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         <PDBx:U23>-0.05766</PDBx:U23>
         <PDBx:U33>0.23602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.06266</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.06794</PDBx:U23>
         <PDBx:U33>0.36890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.06189</PDBx:U23>
         <PDBx:U33>0.30381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1846">
         <PDBx:U11>0.71789</PDBx:U11>
         <PDBx:U12>-0.06420</PDBx:U12>
         <PDBx:U13>0.02858</PDBx:U13>
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         <PDBx:U23>-0.05798</PDBx:U23>
         <PDBx:U33>0.35772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.05369</PDBx:U13>
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         <PDBx:U23>-0.06266</PDBx:U23>
         <PDBx:U33>0.32907</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.05466</PDBx:U23>
         <PDBx:U33>0.36601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.06146</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.06568</PDBx:U23>
         <PDBx:U33>0.32242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.07805</PDBx:U23>
         <PDBx:U33>0.29913</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1902">
         <PDBx:U11>0.28749</PDBx:U11>
         <PDBx:U12>0.02858</PDBx:U12>
         <PDBx:U13>0.03124</PDBx:U13>
         <PDBx:U22>0.19659</PDBx:U22>
         <PDBx:U23>-0.01840</PDBx:U23>
         <PDBx:U33>0.24206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1903">
         <PDBx:U11>0.29131</PDBx:U11>
         <PDBx:U12>0.02823</PDBx:U12>
         <PDBx:U13>0.02164</PDBx:U13>
         <PDBx:U22>0.19120</PDBx:U22>
         <PDBx:U23>-0.02027</PDBx:U23>
         <PDBx:U33>0.22367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1904">
         <PDBx:U11>0.25511</PDBx:U11>
         <PDBx:U12>0.03752</PDBx:U12>
         <PDBx:U13>0.01745</PDBx:U13>
         <PDBx:U22>0.17401</PDBx:U22>
         <PDBx:U23>-0.01518</PDBx:U23>
         <PDBx:U33>0.19909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1905">
         <PDBx:U11>0.26171</PDBx:U11>
         <PDBx:U12>0.03734</PDBx:U12>
         <PDBx:U13>0.01462</PDBx:U13>
         <PDBx:U22>0.17200</PDBx:U22>
         <PDBx:U23>-0.01581</PDBx:U23>
         <PDBx:U33>0.19020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1906">
         <PDBx:U11>0.37114</PDBx:U11>
         <PDBx:U12>0.02416</PDBx:U12>
         <PDBx:U13>0.00601</PDBx:U13>
         <PDBx:U22>0.26106</PDBx:U22>
         <PDBx:U23>-0.02425</PDBx:U23>
         <PDBx:U33>0.28667</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1907">
         <PDBx:U11>0.38157</PDBx:U11>
         <PDBx:U12>0.03259</PDBx:U12>
         <PDBx:U13>-0.00976</PDBx:U13>
         <PDBx:U22>0.29806</PDBx:U22>
         <PDBx:U23>-0.02130</PDBx:U23>
         <PDBx:U33>0.31825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1908">
         <PDBx:U11>0.23567</PDBx:U11>
         <PDBx:U12>0.04475</PDBx:U12>
         <PDBx:U13>0.01819</PDBx:U13>
         <PDBx:U22>0.17849</PDBx:U22>
         <PDBx:U23>-0.01019</PDBx:U23>
         <PDBx:U33>0.20504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1909">
         <PDBx:U11>0.20136</PDBx:U11>
         <PDBx:U12>0.05314</PDBx:U12>
         <PDBx:U13>0.01634</PDBx:U13>
         <PDBx:U22>0.16160</PDBx:U22>
         <PDBx:U23>-0.00583</PDBx:U23>
         <PDBx:U33>0.18082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1910">
         <PDBx:U11>0.23720</PDBx:U11>
         <PDBx:U12>0.05299</PDBx:U12>
         <PDBx:U13>0.02715</PDBx:U13>
         <PDBx:U22>0.19644</PDBx:U22>
         <PDBx:U23>-0.00381</PDBx:U23>
         <PDBx:U33>0.21938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1911">
         <PDBx:U11>0.22906</PDBx:U11>
         <PDBx:U12>0.05569</PDBx:U12>
         <PDBx:U13>0.02405</PDBx:U13>
         <PDBx:U22>0.19124</PDBx:U22>
         <PDBx:U23>-0.00308</PDBx:U23>
         <PDBx:U33>0.20702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1912">
         <PDBx:U11>0.22547</PDBx:U11>
         <PDBx:U12>0.05971</PDBx:U12>
         <PDBx:U13>0.01643</PDBx:U13>
         <PDBx:U22>0.21011</PDBx:U22>
         <PDBx:U23>-0.00076</PDBx:U23>
         <PDBx:U33>0.22868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1913">
         <PDBx:U11>0.22760</PDBx:U11>
         <PDBx:U12>0.06266</PDBx:U12>
         <PDBx:U13>0.00451</PDBx:U13>
         <PDBx:U22>0.22155</PDBx:U22>
         <PDBx:U23>-0.00249</PDBx:U23>
         <PDBx:U33>0.23286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1914">
         <PDBx:U11>0.26024</PDBx:U11>
         <PDBx:U12>0.06227</PDBx:U12>
         <PDBx:U13>-0.00627</PDBx:U13>
         <PDBx:U22>0.24339</PDBx:U22>
         <PDBx:U23>-0.00685</PDBx:U23>
         <PDBx:U33>0.24919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1915">
         <PDBx:U11>0.23263</PDBx:U11>
         <PDBx:U12>0.06570</PDBx:U12>
         <PDBx:U13>0.00615</PDBx:U13>
         <PDBx:U22>0.24522</PDBx:U22>
         <PDBx:U23>0.00094</PDBx:U23>
         <PDBx:U33>0.25659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1916">
         <PDBx:U11>0.19238</PDBx:U11>
         <PDBx:U12>0.05025</PDBx:U12>
         <PDBx:U13>0.03969</PDBx:U13>
         <PDBx:U22>0.14859</PDBx:U22>
         <PDBx:U23>-0.00299</PDBx:U23>
         <PDBx:U33>0.18394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1917">
         <PDBx:U11>0.19972</PDBx:U11>
         <PDBx:U12>0.05084</PDBx:U12>
         <PDBx:U13>0.05028</PDBx:U13>
         <PDBx:U22>0.15799</PDBx:U22>
         <PDBx:U23>-0.00121</PDBx:U23>
         <PDBx:U33>0.19888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1918">
         <PDBx:U11>0.26757</PDBx:U11>
         <PDBx:U12>0.04418</PDBx:U12>
         <PDBx:U13>0.05158</PDBx:U13>
         <PDBx:U22>0.20826</PDBx:U22>
         <PDBx:U23>-0.00624</PDBx:U23>
         <PDBx:U33>0.24518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1919">
         <PDBx:U11>0.20170</PDBx:U11>
         <PDBx:U12>0.04485</PDBx:U12>
         <PDBx:U13>0.05375</PDBx:U13>
         <PDBx:U22>0.14783</PDBx:U22>
         <PDBx:U23>-0.00496</PDBx:U23>
         <PDBx:U33>0.18211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1920">
         <PDBx:U11>0.21313</PDBx:U11>
         <PDBx:U12>0.05011</PDBx:U12>
         <PDBx:U13>0.06352</PDBx:U13>
         <PDBx:U22>0.16908</PDBx:U22>
         <PDBx:U23>-0.00017</PDBx:U23>
         <PDBx:U33>0.22692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1921">
         <PDBx:U11>0.17341</PDBx:U11>
         <PDBx:U12>0.05150</PDBx:U12>
         <PDBx:U13>0.07447</PDBx:U13>
         <PDBx:U22>0.13305</PDBx:U22>
         <PDBx:U23>0.00107</PDBx:U23>
         <PDBx:U33>0.19833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1922">
         <PDBx:U11>0.22228</PDBx:U11>
         <PDBx:U12>0.05595</PDBx:U12>
         <PDBx:U13>0.06228</PDBx:U13>
         <PDBx:U22>0.19410</PDBx:U22>
         <PDBx:U23>0.00637</PDBx:U23>
         <PDBx:U33>0.25618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1923">
         <PDBx:U11>0.23042</PDBx:U11>
         <PDBx:U12>0.03663</PDBx:U12>
         <PDBx:U13>0.05040</PDBx:U13>
         <PDBx:U22>0.14911</PDBx:U22>
         <PDBx:U23>-0.01188</PDBx:U23>
         <PDBx:U33>0.18533</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1924">
         <PDBx:U11>0.27042</PDBx:U11>
         <PDBx:U12>0.02916</PDBx:U12>
         <PDBx:U13>0.05124</PDBx:U13>
         <PDBx:U22>0.16935</PDBx:U22>
         <PDBx:U23>-0.01593</PDBx:U23>
         <PDBx:U33>0.19985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1925">
         <PDBx:U11>0.26795</PDBx:U11>
         <PDBx:U12>0.03203</PDBx:U12>
         <PDBx:U13>0.03931</PDBx:U13>
         <PDBx:U22>0.17033</PDBx:U22>
         <PDBx:U23>-0.01397</PDBx:U23>
         <PDBx:U33>0.18962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1926">
         <PDBx:U11>0.28114</PDBx:U11>
         <PDBx:U12>0.02907</PDBx:U12>
         <PDBx:U13>0.04318</PDBx:U13>
         <PDBx:U22>0.18081</PDBx:U22>
         <PDBx:U23>-0.01386</PDBx:U23>
         <PDBx:U33>0.19830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1927">
         <PDBx:U11>0.26807</PDBx:U11>
         <PDBx:U12>0.02115</PDBx:U12>
         <PDBx:U13>0.04780</PDBx:U13>
         <PDBx:U22>0.14227</PDBx:U22>
         <PDBx:U23>-0.02147</PDBx:U23>
         <PDBx:U33>0.17028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1928">
         <PDBx:U11>0.31328</PDBx:U11>
         <PDBx:U12>0.01285</PDBx:U12>
         <PDBx:U13>0.04763</PDBx:U13>
         <PDBx:U22>0.16433</PDBx:U22>
         <PDBx:U23>-0.02456</PDBx:U23>
         <PDBx:U33>0.18432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1929">
         <PDBx:U11>0.36083</PDBx:U11>
         <PDBx:U12>0.01239</PDBx:U12>
         <PDBx:U13>0.03391</PDBx:U13>
         <PDBx:U22>0.20233</PDBx:U22>
         <PDBx:U23>-0.02361</PDBx:U23>
         <PDBx:U33>0.21167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1930">
         <PDBx:U11>0.35340</PDBx:U11>
         <PDBx:U12>0.00388</PDBx:U12>
         <PDBx:U13>0.06288</PDBx:U13>
         <PDBx:U22>0.18742</PDBx:U22>
         <PDBx:U23>-0.02871</PDBx:U23>
         <PDBx:U33>0.21015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1931">
         <PDBx:U11>0.39283</PDBx:U11>
         <PDBx:U12>0.00252</PDBx:U12>
         <PDBx:U13>0.03941</PDBx:U13>
         <PDBx:U22>0.21039</PDBx:U22>
         <PDBx:U23>-0.02607</PDBx:U23>
         <PDBx:U33>0.21527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1932">
         <PDBx:U11>0.38644</PDBx:U11>
         <PDBx:U12>-0.00324</PDBx:U12>
         <PDBx:U13>0.05793</PDBx:U13>
         <PDBx:U22>0.19995</PDBx:U22>
         <PDBx:U23>-0.02956</PDBx:U23>
         <PDBx:U33>0.21189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1933">
         <PDBx:U11>0.35495</PDBx:U11>
         <PDBx:U12>0.00122</PDBx:U12>
         <PDBx:U13>0.08109</PDBx:U13>
         <PDBx:U22>0.18758</PDBx:U22>
         <PDBx:U23>-0.03216</PDBx:U23>
         <PDBx:U33>0.22162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1934">
         <PDBx:U11>0.38354</PDBx:U11>
         <PDBx:U12>-0.01404</PDBx:U12>
         <PDBx:U13>0.07155</PDBx:U13>
         <PDBx:U22>0.17659</PDBx:U22>
         <PDBx:U23>-0.03343</PDBx:U23>
         <PDBx:U33>0.18669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1967">
         <PDBx:U11>0.29231</PDBx:U11>
         <PDBx:U12>0.06059</PDBx:U12>
         <PDBx:U13>-0.00363</PDBx:U13>
         <PDBx:U22>0.25844</PDBx:U22>
         <PDBx:U23>-0.00544</PDBx:U23>
         <PDBx:U33>0.23813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1968">
         <PDBx:U11>0.32866</PDBx:U11>
         <PDBx:U12>0.06933</PDBx:U12>
         <PDBx:U13>-0.01067</PDBx:U13>
         <PDBx:U22>0.28973</PDBx:U22>
         <PDBx:U23>-0.00663</PDBx:U23>
         <PDBx:U33>0.26990</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1969">
         <PDBx:U11>0.25569</PDBx:U11>
         <PDBx:U12>0.03905</PDBx:U12>
         <PDBx:U13>0.02577</PDBx:U13>
         <PDBx:U22>0.21519</PDBx:U22>
         <PDBx:U23>-0.00441</PDBx:U23>
         <PDBx:U33>0.21448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1970">
         <PDBx:U11>0.28444</PDBx:U11>
         <PDBx:U12>0.03679</PDBx:U12>
         <PDBx:U13>0.03087</PDBx:U13>
         <PDBx:U22>0.26154</PDBx:U22>
         <PDBx:U23>-0.00269</PDBx:U23>
         <PDBx:U33>0.26344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1971">
         <PDBx:U11>0.33763</PDBx:U11>
         <PDBx:U12>0.02424</PDBx:U12>
         <PDBx:U13>0.03646</PDBx:U13>
         <PDBx:U22>0.30074</PDBx:U22>
         <PDBx:U23>-0.00560</PDBx:U23>
         <PDBx:U33>0.30606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1972">
         <PDBx:U11>0.27386</PDBx:U11>
         <PDBx:U12>0.02060</PDBx:U12>
         <PDBx:U13>0.03366</PDBx:U13>
         <PDBx:U22>0.24503</PDBx:U22>
         <PDBx:U23>-0.00569</PDBx:U23>
         <PDBx:U33>0.24898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1973">
         <PDBx:U11>0.19002</PDBx:U11>
         <PDBx:U12>0.04056</PDBx:U12>
         <PDBx:U13>0.04176</PDBx:U13>
         <PDBx:U22>0.18575</PDBx:U22>
         <PDBx:U23>0.00074</PDBx:U23>
         <PDBx:U33>0.19617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1974">
         <PDBx:U11>0.27076</PDBx:U11>
         <PDBx:U12>0.05173</PDBx:U12>
         <PDBx:U13>0.03709</PDBx:U13>
         <PDBx:U22>0.28041</PDBx:U22>
         <PDBx:U23>0.00492</PDBx:U23>
         <PDBx:U33>0.28792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1975">
         <PDBx:U11>0.27348</PDBx:U11>
         <PDBx:U12>0.05587</PDBx:U12>
         <PDBx:U13>0.04635</PDBx:U13>
         <PDBx:U22>0.30134</PDBx:U22>
         <PDBx:U23>0.00962</PDBx:U23>
         <PDBx:U33>0.31886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1976">
         <PDBx:U11>0.31186</PDBx:U11>
         <PDBx:U12>0.05763</PDBx:U12>
         <PDBx:U13>0.02416</PDBx:U13>
         <PDBx:U22>0.33147</PDBx:U22>
         <PDBx:U23>0.00610</PDBx:U23>
         <PDBx:U33>0.32631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1977">
         <PDBx:U11>0.26880</PDBx:U11>
         <PDBx:U12>0.01651</PDBx:U12>
         <PDBx:U13>0.04470</PDBx:U13>
         <PDBx:U22>0.21076</PDBx:U22>
         <PDBx:U23>-0.00807</PDBx:U23>
         <PDBx:U33>0.21999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1978">
         <PDBx:U11>0.26253</PDBx:U11>
         <PDBx:U12>0.01644</PDBx:U12>
         <PDBx:U13>0.04409</PDBx:U13>
         <PDBx:U22>0.20367</PDBx:U22>
         <PDBx:U23>-0.00813</PDBx:U23>
         <PDBx:U33>0.21254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1979">
         <PDBx:U11>0.27735</PDBx:U11>
         <PDBx:U12>0.00315</PDBx:U12>
         <PDBx:U13>0.05089</PDBx:U13>
         <PDBx:U22>0.20255</PDBx:U22>
         <PDBx:U23>-0.01051</PDBx:U23>
         <PDBx:U33>0.21349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1980">
         <PDBx:U11>0.27633</PDBx:U11>
         <PDBx:U12>0.00323</PDBx:U12>
         <PDBx:U13>0.05108</PDBx:U13>
         <PDBx:U22>0.20399</PDBx:U22>
         <PDBx:U23>-0.01036</PDBx:U23>
         <PDBx:U33>0.21519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1981">
         <PDBx:U11>0.29171</PDBx:U11>
         <PDBx:U12>0.00059</PDBx:U12>
         <PDBx:U13>0.03742</PDBx:U13>
         <PDBx:U22>0.20220</PDBx:U22>
         <PDBx:U23>-0.01120</PDBx:U23>
         <PDBx:U33>0.20735</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1982">
         <PDBx:U11>0.28073</PDBx:U11>
         <PDBx:U12>-0.00060</PDBx:U12>
         <PDBx:U13>0.03825</PDBx:U13>
         <PDBx:U22>0.18831</PDBx:U22>
         <PDBx:U23>-0.01140</PDBx:U23>
         <PDBx:U33>0.19369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1983">
         <PDBx:U11>0.29820</PDBx:U11>
         <PDBx:U12>-0.00721</PDBx:U12>
         <PDBx:U13>0.03794</PDBx:U13>
         <PDBx:U22>0.21022</PDBx:U22>
         <PDBx:U23>-0.01177</PDBx:U23>
         <PDBx:U33>0.21661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1984">
         <PDBx:U11>0.32747</PDBx:U11>
         <PDBx:U12>-0.01010</PDBx:U12>
         <PDBx:U13>0.03984</PDBx:U13>
         <PDBx:U22>0.23147</PDBx:U22>
         <PDBx:U23>-0.01220</PDBx:U23>
         <PDBx:U33>0.23832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1985">
         <PDBx:U11>0.33726</PDBx:U11>
         <PDBx:U12>-0.00444</PDBx:U12>
         <PDBx:U13>0.06007</PDBx:U13>
         <PDBx:U22>0.23727</PDBx:U22>
         <PDBx:U23>-0.01301</PDBx:U23>
         <PDBx:U33>0.24970</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1986">
         <PDBx:U11>0.30695</PDBx:U11>
         <PDBx:U12>-0.00503</PDBx:U12>
         <PDBx:U13>0.06543</PDBx:U13>
         <PDBx:U22>0.21686</PDBx:U22>
         <PDBx:U23>-0.01284</PDBx:U23>
         <PDBx:U33>0.23232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1987">
         <PDBx:U11>0.34193</PDBx:U11>
         <PDBx:U12>-0.00298</PDBx:U12>
         <PDBx:U13>0.07553</PDBx:U13>
         <PDBx:U22>0.25361</PDBx:U22>
         <PDBx:U23>-0.01380</PDBx:U23>
         <PDBx:U33>0.27401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1988">
         <PDBx:U11>0.41873</PDBx:U11>
         <PDBx:U12>-0.01985</PDBx:U12>
         <PDBx:U13>0.07587</PDBx:U13>
         <PDBx:U22>0.31748</PDBx:U22>
         <PDBx:U23>-0.01481</PDBx:U23>
         <PDBx:U33>0.33489</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1989">
         <PDBx:U11>0.35900</PDBx:U11>
         <PDBx:U12>-0.01910</PDBx:U12>
         <PDBx:U13>0.06486</PDBx:U13>
         <PDBx:U22>0.23700</PDBx:U22>
         <PDBx:U23>-0.01471</PDBx:U23>
         <PDBx:U33>0.24853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1990">
         <PDBx:U11>0.30986</PDBx:U11>
         <PDBx:U12>-0.00411</PDBx:U12>
         <PDBx:U13>0.05819</PDBx:U13>
         <PDBx:U22>0.19399</PDBx:U22>
         <PDBx:U23>-0.01398</PDBx:U23>
         <PDBx:U33>0.20424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1991">
         <PDBx:U11>0.31615</PDBx:U11>
         <PDBx:U12>-0.01007</PDBx:U12>
         <PDBx:U13>0.08405</PDBx:U13>
         <PDBx:U22>0.20192</PDBx:U22>
         <PDBx:U23>-0.01733</PDBx:U23>
         <PDBx:U33>0.22202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1992">
         <PDBx:U11>0.43500</PDBx:U11>
         <PDBx:U12>-0.02185</PDBx:U12>
         <PDBx:U13>0.08303</PDBx:U13>
         <PDBx:U22>0.36164</PDBx:U22>
         <PDBx:U23>-0.01417</PDBx:U23>
         <PDBx:U33>0.38516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1993">
         <PDBx:U11>0.34291</PDBx:U11>
         <PDBx:U12>0.00724</PDBx:U12>
         <PDBx:U13>0.02499</PDBx:U13>
         <PDBx:U22>0.23889</PDBx:U22>
         <PDBx:U23>-0.01148</PDBx:U23>
         <PDBx:U33>0.23896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1994">
         <PDBx:U11>0.38387</PDBx:U11>
         <PDBx:U12>0.00677</PDBx:U12>
         <PDBx:U13>0.01155</PDBx:U13>
         <PDBx:U22>0.26203</PDBx:U22>
         <PDBx:U23>-0.01262</PDBx:U23>
         <PDBx:U33>0.25886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1995">
         <PDBx:U11>0.35790</PDBx:U11>
         <PDBx:U12>0.01092</PDBx:U12>
         <PDBx:U13>0.00470</PDBx:U13>
         <PDBx:U22>0.25510</PDBx:U22>
         <PDBx:U23>-0.01287</PDBx:U23>
         <PDBx:U33>0.24955</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1996">
         <PDBx:U11>0.36392</PDBx:U11>
         <PDBx:U12>0.00511</PDBx:U12>
         <PDBx:U13>-0.00128</PDBx:U13>
         <PDBx:U22>0.24781</PDBx:U22>
         <PDBx:U23>-0.01456</PDBx:U23>
         <PDBx:U33>0.24295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1997">
         <PDBx:U11>0.35201</PDBx:U11>
         <PDBx:U12>0.01601</PDBx:U12>
         <PDBx:U13>-0.00059</PDBx:U13>
         <PDBx:U22>0.21633</PDBx:U22>
         <PDBx:U23>-0.01304</PDBx:U23>
         <PDBx:U33>0.20951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1998">
         <PDBx:U11>0.46483</PDBx:U11>
         <PDBx:U12>0.01693</PDBx:U12>
         <PDBx:U13>-0.01441</PDBx:U13>
         <PDBx:U22>0.30628</PDBx:U22>
         <PDBx:U23>-0.01445</PDBx:U23>
         <PDBx:U33>0.29890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1999">
         <PDBx:U11>0.57715</PDBx:U11>
         <PDBx:U12>0.02363</PDBx:U12>
         <PDBx:U13>-0.02571</PDBx:U13>
         <PDBx:U22>0.39909</PDBx:U22>
         <PDBx:U23>-0.01472</PDBx:U23>
         <PDBx:U33>0.39056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2000">
         <PDBx:U11>0.63302</PDBx:U11>
         <PDBx:U12>0.02785</PDBx:U12>
         <PDBx:U13>-0.03840</PDBx:U13>
         <PDBx:U22>0.43789</PDBx:U22>
         <PDBx:U23>-0.01594</PDBx:U23>
         <PDBx:U33>0.43062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2001">
         <PDBx:U11>0.53682</PDBx:U11>
         <PDBx:U12>0.02486</PDBx:U12>
         <PDBx:U13>-0.02261</PDBx:U13>
         <PDBx:U22>0.36018</PDBx:U22>
         <PDBx:U23>-0.01401</PDBx:U23>
         <PDBx:U33>0.35044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2002">
         <PDBx:U11>0.27422</PDBx:U11>
         <PDBx:U12>0.02022</PDBx:U12>
         <PDBx:U13>0.00502</PDBx:U13>
         <PDBx:U22>0.20044</PDBx:U22>
         <PDBx:U23>-0.01116</PDBx:U23>
         <PDBx:U33>0.19191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2003">
         <PDBx:U11>0.29591</PDBx:U11>
         <PDBx:U12>0.02292</PDBx:U12>
         <PDBx:U13>-0.00117</PDBx:U13>
         <PDBx:U22>0.24069</PDBx:U22>
         <PDBx:U23>-0.01132</PDBx:U23>
         <PDBx:U33>0.22787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2004">
         <PDBx:U11>0.34017</PDBx:U11>
         <PDBx:U12>0.01102</PDBx:U12>
         <PDBx:U13>0.00575</PDBx:U13>
         <PDBx:U22>0.29267</PDBx:U22>
         <PDBx:U23>-0.01142</PDBx:U23>
         <PDBx:U33>0.28485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2005">
         <PDBx:U11>0.34155</PDBx:U11>
         <PDBx:U12>0.00708</PDBx:U12>
         <PDBx:U13>-0.00128</PDBx:U13>
         <PDBx:U22>0.29588</PDBx:U22>
         <PDBx:U23>-0.01331</PDBx:U23>
         <PDBx:U33>0.28604</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2006">
         <PDBx:U11>0.24534</PDBx:U11>
         <PDBx:U12>0.03458</PDBx:U12>
         <PDBx:U13>-0.00145</PDBx:U13>
         <PDBx:U22>0.21869</PDBx:U22>
         <PDBx:U23>-0.00812</PDBx:U23>
         <PDBx:U33>0.20069</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2007">
         <PDBx:U11>0.29754</PDBx:U11>
         <PDBx:U12>0.04648</PDBx:U12>
         <PDBx:U13>-0.00936</PDBx:U13>
         <PDBx:U22>0.26991</PDBx:U22>
         <PDBx:U23>-0.00841</PDBx:U23>
         <PDBx:U33>0.24503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2008">
         <PDBx:U11>0.29588</PDBx:U11>
         <PDBx:U12>0.04841</PDBx:U12>
         <PDBx:U13>-0.01816</PDBx:U13>
         <PDBx:U22>0.24560</PDBx:U22>
         <PDBx:U23>-0.01204</PDBx:U23>
         <PDBx:U33>0.21949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2009">
         <PDBx:U11>0.27459</PDBx:U11>
         <PDBx:U12>0.05592</PDBx:U12>
         <PDBx:U13>-0.00795</PDBx:U13>
         <PDBx:U22>0.26949</PDBx:U22>
         <PDBx:U23>-0.00473</PDBx:U23>
         <PDBx:U33>0.24000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2010">
         <PDBx:U11>0.29242</PDBx:U11>
         <PDBx:U12>0.05987</PDBx:U12>
         <PDBx:U13>-0.02480</PDBx:U13>
         <PDBx:U22>0.24505</PDBx:U22>
         <PDBx:U23>-0.01282</PDBx:U23>
         <PDBx:U33>0.21338</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2011">
         <PDBx:U11>0.25885</PDBx:U11>
         <PDBx:U12>0.06560</PDBx:U12>
         <PDBx:U13>-0.01346</PDBx:U13>
         <PDBx:U22>0.25541</PDBx:U22>
         <PDBx:U23>-0.00511</PDBx:U23>
         <PDBx:U33>0.21959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2012">
         <PDBx:U11>0.27566</PDBx:U11>
         <PDBx:U12>0.06787</PDBx:U12>
         <PDBx:U13>-0.02171</PDBx:U13>
         <PDBx:U22>0.25321</PDBx:U22>
         <PDBx:U23>-0.00955</PDBx:U23>
         <PDBx:U33>0.21605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2013">
         <PDBx:U11>0.30668</PDBx:U11>
         <PDBx:U12>0.07809</PDBx:U12>
         <PDBx:U13>-0.02623</PDBx:U13>
         <PDBx:U22>0.29032</PDBx:U22>
         <PDBx:U23>-0.01019</PDBx:U23>
         <PDBx:U33>0.24745</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2014">
         <PDBx:U11>0.30419</PDBx:U11>
         <PDBx:U12>0.00527</PDBx:U12>
         <PDBx:U13>0.01979</PDBx:U13>
         <PDBx:U22>0.26264</PDBx:U22>
         <PDBx:U23>-0.00996</PDBx:U23>
         <PDBx:U33>0.26176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2015">
         <PDBx:U11>0.27087</PDBx:U11>
         <PDBx:U12>-0.00550</PDBx:U12>
         <PDBx:U13>0.02861</PDBx:U13>
         <PDBx:U22>0.24189</PDBx:U22>
         <PDBx:U23>-0.01014</PDBx:U23>
         <PDBx:U33>0.24701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2016">
         <PDBx:U11>0.29252</PDBx:U11>
         <PDBx:U12>-0.02069</PDBx:U12>
         <PDBx:U13>0.03048</PDBx:U13>
         <PDBx:U22>0.23800</PDBx:U22>
         <PDBx:U23>-0.01294</PDBx:U23>
         <PDBx:U33>0.24623</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2017">
         <PDBx:U11>0.33244</PDBx:U11>
         <PDBx:U12>-0.03034</PDBx:U12>
         <PDBx:U13>0.03088</PDBx:U13>
         <PDBx:U22>0.28580</PDBx:U22>
         <PDBx:U23>-0.01404</PDBx:U23>
         <PDBx:U33>0.29665</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2018">
         <PDBx:U11>0.29001</PDBx:U11>
         <PDBx:U12>-0.00519</PDBx:U12>
         <PDBx:U13>0.04454</PDBx:U13>
         <PDBx:U22>0.27421</PDBx:U22>
         <PDBx:U23>-0.00851</PDBx:U23>
         <PDBx:U33>0.28701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2019">
         <PDBx:U11>0.34645</PDBx:U11>
         <PDBx:U12>-0.01436</PDBx:U12>
         <PDBx:U13>0.05587</PDBx:U13>
         <PDBx:U22>0.34865</PDBx:U22>
         <PDBx:U23>-0.00889</PDBx:U23>
         <PDBx:U33>0.36940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2020">
         <PDBx:U11>0.36563</PDBx:U11>
         <PDBx:U12>-0.00893</PDBx:U12>
         <PDBx:U13>0.05355</PDBx:U13>
         <PDBx:U22>0.40069</PDBx:U22>
         <PDBx:U23>-0.00628</PDBx:U23>
         <PDBx:U33>0.42328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2021">
         <PDBx:U11>0.33912</PDBx:U11>
         <PDBx:U12>-0.02852</PDBx:U12>
         <PDBx:U13>0.06892</PDBx:U13>
         <PDBx:U22>0.32636</PDBx:U22>
         <PDBx:U23>-0.01163</PDBx:U23>
         <PDBx:U33>0.35248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2022">
         <PDBx:U11>0.36166</PDBx:U11>
         <PDBx:U12>-0.01635</PDBx:U12>
         <PDBx:U13>0.06319</PDBx:U13>
         <PDBx:U22>0.41669</PDBx:U22>
         <PDBx:U23>-0.00671</PDBx:U23>
         <PDBx:U33>0.44777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2023">
         <PDBx:U11>0.33072</PDBx:U11>
         <PDBx:U12>-0.03701</PDBx:U12>
         <PDBx:U13>0.08065</PDBx:U13>
         <PDBx:U22>0.33758</PDBx:U22>
         <PDBx:U23>-0.01248</PDBx:U23>
         <PDBx:U33>0.37153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2024">
         <PDBx:U11>0.28418</PDBx:U11>
         <PDBx:U12>-0.03053</PDBx:U12>
         <PDBx:U13>0.07740</PDBx:U13>
         <PDBx:U22>0.32620</PDBx:U22>
         <PDBx:U23>-0.01021</PDBx:U23>
         <PDBx:U33>0.36340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2025">
         <PDBx:U11>0.33492</PDBx:U11>
         <PDBx:U12>-0.03816</PDBx:U12>
         <PDBx:U13>0.08833</PDBx:U13>
         <PDBx:U22>0.39960</PDBx:U22>
         <PDBx:U23>-0.01119</PDBx:U23>
         <PDBx:U33>0.44577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2026">
         <PDBx:U11>0.34047</PDBx:U11>
         <PDBx:U12>-0.02371</PDBx:U12>
         <PDBx:U13>0.03115</PDBx:U13>
         <PDBx:U22>0.25491</PDBx:U22>
         <PDBx:U23>-0.01372</PDBx:U23>
         <PDBx:U33>0.26300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2027">
         <PDBx:U11>0.35653</PDBx:U11>
         <PDBx:U12>-0.03874</PDBx:U12>
         <PDBx:U13>0.03383</PDBx:U13>
         <PDBx:U22>0.24181</PDBx:U22>
         <PDBx:U23>-0.01505</PDBx:U23>
         <PDBx:U33>0.25294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2028">
         <PDBx:U11>0.48040</PDBx:U11>
         <PDBx:U12>-0.03798</PDBx:U12>
         <PDBx:U13>0.01775</PDBx:U13>
         <PDBx:U22>0.34038</PDBx:U22>
         <PDBx:U23>-0.01621</PDBx:U23>
         <PDBx:U33>0.34962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2029">
         <PDBx:U11>0.49113</PDBx:U11>
         <PDBx:U12>-0.05097</PDBx:U12>
         <PDBx:U13>0.01737</PDBx:U13>
         <PDBx:U22>0.33122</PDBx:U22>
         <PDBx:U23>-0.01703</PDBx:U23>
         <PDBx:U33>0.34451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2030">
         <PDBx:U11>0.32466</PDBx:U11>
         <PDBx:U12>-0.04378</PDBx:U12>
         <PDBx:U13>0.04432</PDBx:U13>
         <PDBx:U22>0.18698</PDBx:U22>
         <PDBx:U23>-0.01468</PDBx:U23>
         <PDBx:U33>0.19863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2031">
         <PDBx:U11>0.38676</PDBx:U11>
         <PDBx:U12>-0.04671</PDBx:U12>
         <PDBx:U13>0.06325</PDBx:U13>
         <PDBx:U22>0.26802</PDBx:U22>
         <PDBx:U23>-0.01500</PDBx:U23>
         <PDBx:U33>0.28368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2032">
         <PDBx:U11>0.40931</PDBx:U11>
         <PDBx:U12>-0.05270</PDBx:U12>
         <PDBx:U13>0.07313</PDBx:U13>
         <PDBx:U22>0.26365</PDBx:U22>
         <PDBx:U23>-0.01577</PDBx:U23>
         <PDBx:U33>0.27776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2033">
         <PDBx:U11>0.45035</PDBx:U11>
         <PDBx:U12>-0.05902</PDBx:U12>
         <PDBx:U13>0.07428</PDBx:U13>
         <PDBx:U22>0.34844</PDBx:U22>
         <PDBx:U23>-0.01592</PDBx:U23>
         <PDBx:U33>0.36995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2034">
         <PDBx:U11>0.37442</PDBx:U11>
         <PDBx:U12>-0.02337</PDBx:U12>
         <PDBx:U13>0.00526</PDBx:U13>
         <PDBx:U22>0.23332</PDBx:U22>
         <PDBx:U23>-0.01645</PDBx:U23>
         <PDBx:U33>0.23771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2035">
         <PDBx:U11>0.42164</PDBx:U11>
         <PDBx:U12>-0.02041</PDBx:U12>
         <PDBx:U13>-0.00923</PDBx:U13>
         <PDBx:U22>0.25355</PDBx:U22>
         <PDBx:U23>-0.01810</PDBx:U23>
         <PDBx:U33>0.25802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2036">
         <PDBx:U11>0.52708</PDBx:U11>
         <PDBx:U12>-0.01996</PDBx:U12>
         <PDBx:U13>-0.01208</PDBx:U13>
         <PDBx:U22>0.32677</PDBx:U22>
         <PDBx:U23>-0.01677</PDBx:U23>
         <PDBx:U33>0.33226</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2037">
         <PDBx:U11>0.54519</PDBx:U11>
         <PDBx:U12>-0.01504</PDBx:U12>
         <PDBx:U13>-0.02527</PDBx:U13>
         <PDBx:U22>0.32100</PDBx:U22>
         <PDBx:U23>-0.01772</PDBx:U23>
         <PDBx:U33>0.32820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>230</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2038">
         <PDBx:U11>0.44497</PDBx:U11>
         <PDBx:U12>-0.02440</PDBx:U12>
         <PDBx:U13>-0.00073</PDBx:U13>
         <PDBx:U22>0.24272</PDBx:U22>
         <PDBx:U23>-0.01486</PDBx:U23>
         <PDBx:U33>0.24743</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2039">
         <PDBx:U11>0.47701</PDBx:U11>
         <PDBx:U12>-0.02523</PDBx:U12>
         <PDBx:U13>-0.00402</PDBx:U13>
         <PDBx:U22>0.24409</PDBx:U22>
         <PDBx:U23>-0.01339</PDBx:U23>
         <PDBx:U33>0.24791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2040">
         <PDBx:U11>0.46172</PDBx:U11>
         <PDBx:U12>-0.02316</PDBx:U12>
         <PDBx:U13>0.00643</PDBx:U13>
         <PDBx:U22>0.24125</PDBx:U22>
         <PDBx:U23>-0.01290</PDBx:U23>
         <PDBx:U33>0.24168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2041">
         <PDBx:U11>0.47078</PDBx:U11>
         <PDBx:U12>-0.02519</PDBx:U12>
         <PDBx:U13>0.01965</PDBx:U13>
         <PDBx:U22>0.27577</PDBx:U22>
         <PDBx:U23>-0.01336</PDBx:U23>
         <PDBx:U33>0.27717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2042">
         <PDBx:U11>0.60259</PDBx:U11>
         <PDBx:U12>-0.04215</PDBx:U12>
         <PDBx:U13>0.00012</PDBx:U13>
         <PDBx:U22>0.33545</PDBx:U22>
         <PDBx:U23>-0.01182</PDBx:U23>
         <PDBx:U33>0.34282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2043">
         <PDBx:U11>0.54312</PDBx:U11>
         <PDBx:U12>-0.05746</PDBx:U12>
         <PDBx:U13>0.01924</PDBx:U13>
         <PDBx:U22>0.28758</PDBx:U22>
         <PDBx:U23>-0.01198</PDBx:U23>
         <PDBx:U33>0.29660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2044">
         <PDBx:U11>0.53465</PDBx:U11>
         <PDBx:U12>-0.06338</PDBx:U12>
         <PDBx:U13>0.03477</PDBx:U13>
         <PDBx:U22>0.28031</PDBx:U22>
         <PDBx:U23>-0.01176</PDBx:U23>
         <PDBx:U33>0.28644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2045">
         <PDBx:U11>0.59769</PDBx:U11>
         <PDBx:U12>-0.06603</PDBx:U12>
         <PDBx:U13>0.02184</PDBx:U13>
         <PDBx:U22>0.35260</PDBx:U22>
         <PDBx:U23>-0.01309</PDBx:U23>
         <PDBx:U33>0.36646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2046">
         <PDBx:U11>0.63370</PDBx:U11>
         <PDBx:U12>-0.07646</PDBx:U12>
         <PDBx:U13>0.05377</PDBx:U13>
         <PDBx:U22>0.39190</PDBx:U22>
         <PDBx:U23>-0.01270</PDBx:U23>
         <PDBx:U33>0.40051</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2047">
         <PDBx:U11>0.58356</PDBx:U11>
         <PDBx:U12>-0.07990</PDBx:U12>
         <PDBx:U13>0.03956</PDBx:U13>
         <PDBx:U22>0.35269</PDBx:U22>
         <PDBx:U23>-0.01351</PDBx:U23>
         <PDBx:U33>0.36898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2048">
         <PDBx:U11>0.52257</PDBx:U11>
         <PDBx:U12>-0.08456</PDBx:U12>
         <PDBx:U13>0.05608</PDBx:U13>
         <PDBx:U22>0.29390</PDBx:U22>
         <PDBx:U23>-0.01335</PDBx:U23>
         <PDBx:U33>0.30787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>231</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2049">
         <PDBx:U11>0.49502</PDBx:U11>
         <PDBx:U12>-0.01882</PDBx:U12>
         <PDBx:U13>-0.00044</PDBx:U13>
         <PDBx:U22>0.25588</PDBx:U22>
         <PDBx:U23>-0.01218</PDBx:U23>
         <PDBx:U33>0.25333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2050">
         <PDBx:U11>0.52528</PDBx:U11>
         <PDBx:U12>-0.01791</PDBx:U12>
         <PDBx:U13>0.00823</PDBx:U13>
         <PDBx:U22>0.29327</PDBx:U22>
         <PDBx:U23>-0.01256</PDBx:U23>
         <PDBx:U33>0.28786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2051">
         <PDBx:U11>0.52123</PDBx:U11>
         <PDBx:U12>-0.03374</PDBx:U12>
         <PDBx:U13>0.02487</PDBx:U13>
         <PDBx:U22>0.27374</PDBx:U22>
         <PDBx:U23>-0.01275</PDBx:U23>
         <PDBx:U33>0.26789</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2052">
         <PDBx:U11>0.54285</PDBx:U11>
         <PDBx:U12>-0.04560</PDBx:U12>
         <PDBx:U13>0.02593</PDBx:U13>
         <PDBx:U22>0.26828</PDBx:U22>
         <PDBx:U23>-0.01144</PDBx:U23>
         <PDBx:U33>0.26218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2053">
         <PDBx:U11>0.57278</PDBx:U11>
         <PDBx:U12>-0.00957</PDBx:U12>
         <PDBx:U13>-0.00561</PDBx:U13>
         <PDBx:U22>0.32610</PDBx:U22>
         <PDBx:U23>-0.01219</PDBx:U23>
         <PDBx:U33>0.31712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2054">
         <PDBx:U11>0.65584</PDBx:U11>
         <PDBx:U12>-0.01046</PDBx:U12>
         <PDBx:U13>0.00310</PDBx:U13>
         <PDBx:U22>0.41513</PDBx:U22>
         <PDBx:U23>-0.01332</PDBx:U23>
         <PDBx:U33>0.40386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2055">
         <PDBx:U11>0.64619</PDBx:U11>
         <PDBx:U12>-0.01657</PDBx:U12>
         <PDBx:U13>-0.01469</PDBx:U13>
         <PDBx:U22>0.35936</PDBx:U22>
         <PDBx:U23>-0.01022</PDBx:U23>
         <PDBx:U33>0.34931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2056">
         <PDBx:U11>0.52304</PDBx:U11>
         <PDBx:U12>-0.03425</PDBx:U12>
         <PDBx:U13>0.03911</PDBx:U13>
         <PDBx:U22>0.29189</PDBx:U22>
         <PDBx:U23>-0.01456</PDBx:U23>
         <PDBx:U33>0.28645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2057">
         <PDBx:U11>0.60956</PDBx:U11>
         <PDBx:U12>-0.04829</PDBx:U12>
         <PDBx:U13>0.05609</PDBx:U13>
         <PDBx:U22>0.36204</PDBx:U22>
         <PDBx:U23>-0.01603</PDBx:U23>
         <PDBx:U33>0.35502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2058">
         <PDBx:U11>0.59309</PDBx:U11>
         <PDBx:U12>-0.05033</PDBx:U12>
         <PDBx:U13>0.05166</PDBx:U13>
         <PDBx:U22>0.31742</PDBx:U22>
         <PDBx:U23>-0.01650</PDBx:U23>
         <PDBx:U33>0.30332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2059">
         <PDBx:U11>0.63439</PDBx:U11>
         <PDBx:U12>-0.06212</PDBx:U12>
         <PDBx:U13>0.06545</PDBx:U13>
         <PDBx:U22>0.34131</PDBx:U22>
         <PDBx:U23>-0.01827</PDBx:U23>
         <PDBx:U33>0.32337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2060">
         <PDBx:U11>0.58929</PDBx:U11>
         <PDBx:U12>-0.04894</PDBx:U12>
         <PDBx:U13>0.07578</PDBx:U13>
         <PDBx:U22>0.36919</PDBx:U22>
         <PDBx:U23>-0.01878</PDBx:U23>
         <PDBx:U33>0.36772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2061">
         <PDBx:U11>0.61413</PDBx:U11>
         <PDBx:U12>-0.05128</PDBx:U12>
         <PDBx:U13>0.08150</PDBx:U13>
         <PDBx:U22>0.41815</PDBx:U22>
         <PDBx:U23>-0.01812</PDBx:U23>
         <PDBx:U33>0.42286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2062">
         <PDBx:U11>0.47146</PDBx:U11>
         <PDBx:U12>-0.03523</PDBx:U12>
         <PDBx:U13>0.07225</PDBx:U13>
         <PDBx:U22>0.27131</PDBx:U22>
         <PDBx:U23>-0.01954</PDBx:U23>
         <PDBx:U33>0.27213</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2063">
         <PDBx:U11>0.52752</PDBx:U11>
         <PDBx:U12>-0.03959</PDBx:U12>
         <PDBx:U13>0.03286</PDBx:U13>
         <PDBx:U22>0.24708</PDBx:U22>
         <PDBx:U23>-0.01532</PDBx:U23>
         <PDBx:U33>0.23048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2064">
         <PDBx:U11>0.52395</PDBx:U11>
         <PDBx:U12>-0.04155</PDBx:U12>
         <PDBx:U13>0.02465</PDBx:U13>
         <PDBx:U22>0.21644</PDBx:U22>
         <PDBx:U23>-0.01541</PDBx:U23>
         <PDBx:U33>0.19260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2097">
         <PDBx:U11>1.01991</PDBx:U11>
         <PDBx:U12>0.00152</PDBx:U12>
         <PDBx:U13>-0.10733</PDBx:U13>
         <PDBx:U22>0.62626</PDBx:U22>
         <PDBx:U23>0.00020</PDBx:U23>
         <PDBx:U33>0.62717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2098">
         <PDBx:U11>0.91458</PDBx:U11>
         <PDBx:U12>0.01343</PDBx:U12>
         <PDBx:U13>-0.10323</PDBx:U13>
         <PDBx:U22>0.54973</PDBx:U22>
         <PDBx:U23>-0.00266</PDBx:U23>
         <PDBx:U33>0.55434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2099">
         <PDBx:U11>1.03067</PDBx:U11>
         <PDBx:U12>-0.00686</PDBx:U12>
         <PDBx:U13>-0.11328</PDBx:U13>
         <PDBx:U22>0.59925</PDBx:U22>
         <PDBx:U23>0.00330</PDBx:U23>
         <PDBx:U33>0.60396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2100">
         <PDBx:U11>0.83125</PDBx:U11>
         <PDBx:U12>0.02199</PDBx:U12>
         <PDBx:U13>-0.09934</PDBx:U13>
         <PDBx:U22>0.49990</PDBx:U22>
         <PDBx:U23>-0.00571</PDBx:U23>
         <PDBx:U33>0.50085</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2101">
         <PDBx:U11>1.04219</PDBx:U11>
         <PDBx:U12>-0.02173</PDBx:U12>
         <PDBx:U13>-0.10074</PDBx:U13>
         <PDBx:U22>0.58610</PDBx:U22>
         <PDBx:U23>0.00570</PDBx:U23>
         <PDBx:U33>0.58808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2102">
         <PDBx:U11>0.87919</PDBx:U11>
         <PDBx:U12>0.01406</PDBx:U12>
         <PDBx:U13>-0.10499</PDBx:U13>
         <PDBx:U22>0.49951</PDBx:U22>
         <PDBx:U23>-0.00217</PDBx:U23>
         <PDBx:U33>0.51137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2103">
         <PDBx:U11>1.04403</PDBx:U11>
         <PDBx:U12>-0.00279</PDBx:U12>
         <PDBx:U13>-0.13037</PDBx:U13>
         <PDBx:U22>0.59545</PDBx:U22>
         <PDBx:U23>0.00398</PDBx:U23>
         <PDBx:U33>0.60595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2104">
         <PDBx:U11>0.80473</PDBx:U11>
         <PDBx:U12>0.02793</PDBx:U12>
         <PDBx:U13>-0.09874</PDBx:U13>
         <PDBx:U22>0.47949</PDBx:U22>
         <PDBx:U23>-0.00676</PDBx:U23>
         <PDBx:U33>0.48460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2105">
         <PDBx:U11>1.08828</PDBx:U11>
         <PDBx:U12>-0.02679</PDBx:U12>
         <PDBx:U13>-0.11010</PDBx:U13>
         <PDBx:U22>0.60001</PDBx:U22>
         <PDBx:U23>0.00775</PDBx:U23>
         <PDBx:U33>0.60569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2106">
         <PDBx:U11>0.85930</PDBx:U11>
         <PDBx:U12>0.02318</PDBx:U12>
         <PDBx:U13>-0.10228</PDBx:U13>
         <PDBx:U22>0.50491</PDBx:U22>
         <PDBx:U23>-0.00484</PDBx:U23>
         <PDBx:U33>0.51692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2107">
         <PDBx:U11>1.07461</PDBx:U11>
         <PDBx:U12>-0.01509</PDBx:U12>
         <PDBx:U13>-0.12862</PDBx:U13>
         <PDBx:U22>0.58992</PDBx:U22>
         <PDBx:U23>0.00701</PDBx:U23>
         <PDBx:U33>0.60080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>382</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2108">
         <PDBx:U11>0.94378</PDBx:U11>
         <PDBx:U12>-0.03045</PDBx:U12>
         <PDBx:U13>-0.07735</PDBx:U13>
         <PDBx:U22>0.52747</PDBx:U22>
         <PDBx:U23>0.00126</PDBx:U23>
         <PDBx:U33>0.50686</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2109">
         <PDBx:U11>0.83015</PDBx:U11>
         <PDBx:U12>-0.03876</PDBx:U12>
         <PDBx:U13>-0.07731</PDBx:U13>
         <PDBx:U22>0.40125</PDBx:U22>
         <PDBx:U23>0.00090</PDBx:U23>
         <PDBx:U33>0.37371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2110">
         <PDBx:U11>0.84424</PDBx:U11>
         <PDBx:U12>-0.04372</PDBx:U12>
         <PDBx:U13>-0.06008</PDBx:U13>
         <PDBx:U22>0.43367</PDBx:U22>
         <PDBx:U23>-0.00360</PDBx:U23>
         <PDBx:U33>0.39811</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2111">
         <PDBx:U11>0.84830</PDBx:U11>
         <PDBx:U12>-0.04946</PDBx:U12>
         <PDBx:U13>-0.04142</PDBx:U13>
         <PDBx:U22>0.44232</PDBx:U22>
         <PDBx:U23>-0.00513</PDBx:U23>
         <PDBx:U33>0.40545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2112">
         <PDBx:U11>0.88445</PDBx:U11>
         <PDBx:U12>-0.05210</PDBx:U12>
         <PDBx:U13>-0.07371</PDBx:U13>
         <PDBx:U22>0.41853</PDBx:U22>
         <PDBx:U23>0.00401</PDBx:U23>
         <PDBx:U33>0.39034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2113">
         <PDBx:U11>1.00556</PDBx:U11>
         <PDBx:U12>-0.06170</PDBx:U12>
         <PDBx:U13>-0.07222</PDBx:U13>
         <PDBx:U22>0.52517</PDBx:U22>
         <PDBx:U23>0.00326</PDBx:U23>
         <PDBx:U33>0.48829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2114">
         <PDBx:U11>1.02396</PDBx:U11>
         <PDBx:U12>-0.05692</PDBx:U12>
         <PDBx:U13>-0.08960</PDBx:U13>
         <PDBx:U22>0.54099</PDBx:U22>
         <PDBx:U23>0.00387</PDBx:U23>
         <PDBx:U33>0.50344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2115">
         <PDBx:U11>1.09178</PDBx:U11>
         <PDBx:U12>-0.07400</PDBx:U12>
         <PDBx:U13>-0.05340</PDBx:U13>
         <PDBx:U22>0.60358</PDBx:U22>
         <PDBx:U23>0.00137</PDBx:U23>
         <PDBx:U33>0.56056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2116">
         <PDBx:U11>0.80559</PDBx:U11>
         <PDBx:U12>-0.04184</PDBx:U12>
         <PDBx:U13>-0.06626</PDBx:U13>
         <PDBx:U22>0.40486</PDBx:U22>
         <PDBx:U23>-0.00652</PDBx:U23>
         <PDBx:U33>0.36497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2117">
         <PDBx:U11>0.77886</PDBx:U11>
         <PDBx:U12>-0.04446</PDBx:U12>
         <PDBx:U13>-0.05161</PDBx:U13>
         <PDBx:U22>0.39667</PDBx:U22>
         <PDBx:U23>-0.01228</PDBx:U23>
         <PDBx:U33>0.35218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2118">
         <PDBx:U11>0.68672</PDBx:U11>
         <PDBx:U12>-0.05858</PDBx:U12>
         <PDBx:U13>-0.03109</PDBx:U13>
         <PDBx:U22>0.28828</PDBx:U22>
         <PDBx:U23>-0.01412</PDBx:U23>
         <PDBx:U33>0.23905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2119">
         <PDBx:U11>0.68469</PDBx:U11>
         <PDBx:U12>-0.06072</PDBx:U12>
         <PDBx:U13>-0.01250</PDBx:U13>
         <PDBx:U22>0.29985</PDBx:U22>
         <PDBx:U23>-0.01853</PDBx:U23>
         <PDBx:U33>0.25118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2120">
         <PDBx:U11>0.90339</PDBx:U11>
         <PDBx:U12>-0.04072</PDBx:U12>
         <PDBx:U13>-0.06407</PDBx:U13>
         <PDBx:U22>0.53230</PDBx:U22>
         <PDBx:U23>-0.01564</PDBx:U23>
         <PDBx:U33>0.48531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2121">
         <PDBx:U11>0.96724</PDBx:U11>
         <PDBx:U12>-0.02840</PDBx:U12>
         <PDBx:U13>-0.07222</PDBx:U13>
         <PDBx:U22>0.62349</PDBx:U22>
         <PDBx:U23>-0.01745</PDBx:U23>
         <PDBx:U33>0.58094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2122">
         <PDBx:U11>0.77305</PDBx:U11>
         <PDBx:U12>-0.06807</PDBx:U12>
         <PDBx:U13>-0.03359</PDBx:U13>
         <PDBx:U22>0.34548</PDBx:U22>
         <PDBx:U23>-0.01144</PDBx:U23>
         <PDBx:U33>0.29260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2123">
         <PDBx:U11>0.77282</PDBx:U11>
         <PDBx:U12>-0.08174</PDBx:U12>
         <PDBx:U13>-0.01288</PDBx:U13>
         <PDBx:U22>0.32963</PDBx:U22>
         <PDBx:U23>-0.01393</PDBx:U23>
         <PDBx:U33>0.27257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2124">
         <PDBx:U11>0.77161</PDBx:U11>
         <PDBx:U12>-0.08622</PDBx:U12>
         <PDBx:U13>0.00322</PDBx:U13>
         <PDBx:U22>0.32642</PDBx:U22>
         <PDBx:U23>-0.01298</PDBx:U23>
         <PDBx:U33>0.27363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2125">
         <PDBx:U11>0.78921</PDBx:U11>
         <PDBx:U12>-0.09242</PDBx:U12>
         <PDBx:U13>0.02498</PDBx:U13>
         <PDBx:U22>0.35028</PDBx:U22>
         <PDBx:U23>-0.01755</PDBx:U23>
         <PDBx:U33>0.29779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2126">
         <PDBx:U11>0.86461</PDBx:U11>
         <PDBx:U12>-0.09143</PDBx:U12>
         <PDBx:U13>-0.01986</PDBx:U13>
         <PDBx:U22>0.38922</PDBx:U22>
         <PDBx:U23>-0.01171</PDBx:U23>
         <PDBx:U33>0.32631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2127">
         <PDBx:U11>0.83787</PDBx:U11>
         <PDBx:U12>-0.10523</PDBx:U12>
         <PDBx:U13>0.00134</PDBx:U13>
         <PDBx:U22>0.34790</PDBx:U22>
         <PDBx:U23>-0.01596</PDBx:U23>
         <PDBx:U33>0.27969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2128">
         <PDBx:U11>0.96650</PDBx:U11>
         <PDBx:U12>-0.11371</PDBx:U12>
         <PDBx:U13>-0.00733</PDBx:U13>
         <PDBx:U22>0.44842</PDBx:U22>
         <PDBx:U23>-0.01520</PDBx:U23>
         <PDBx:U33>0.37192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01620</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.32188</PDBx:U22>
         <PDBx:U23>-0.01112</PDBx:U23>
         <PDBx:U33>0.29133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U23>-0.00618</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.03396</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.03900</PDBx:U23>
         <PDBx:U33>0.23294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.04401</PDBx:U23>
         <PDBx:U33>0.24672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.59719</PDBx:U11>
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         <PDBx:U13>0.10186</PDBx:U13>
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         <PDBx:U23>-0.04028</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.24044</PDBx:U22>
         <PDBx:U23>-0.03719</PDBx:U23>
         <PDBx:U33>0.22494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.04534</PDBx:U12>
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         <PDBx:U22>0.29209</PDBx:U22>
         <PDBx:U23>-0.04051</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2178">
         <PDBx:U11>0.53208</PDBx:U11>
         <PDBx:U12>-0.03519</PDBx:U12>
         <PDBx:U13>0.04626</PDBx:U13>
         <PDBx:U22>0.25296</PDBx:U22>
         <PDBx:U23>-0.03679</PDBx:U23>
         <PDBx:U33>0.23493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2179">
         <PDBx:U11>0.57305</PDBx:U11>
         <PDBx:U12>-0.08792</PDBx:U12>
         <PDBx:U13>0.13818</PDBx:U13>
         <PDBx:U22>0.24602</PDBx:U22>
         <PDBx:U23>-0.04527</PDBx:U23>
         <PDBx:U33>0.23635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2180">
         <PDBx:U11>0.56250</PDBx:U11>
         <PDBx:U12>-0.09516</PDBx:U12>
         <PDBx:U13>0.15938</PDBx:U13>
         <PDBx:U22>0.23323</PDBx:U22>
         <PDBx:U23>-0.05132</PDBx:U23>
         <PDBx:U33>0.23097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2181">
         <PDBx:U11>0.65040</PDBx:U11>
         <PDBx:U12>-0.09991</PDBx:U12>
         <PDBx:U13>0.17318</PDBx:U13>
         <PDBx:U22>0.33042</PDBx:U22>
         <PDBx:U23>-0.05266</PDBx:U23>
         <PDBx:U33>0.33334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2182">
         <PDBx:U11>0.61433</PDBx:U11>
         <PDBx:U12>-0.09897</PDBx:U12>
         <PDBx:U13>0.19060</PDBx:U13>
         <PDBx:U22>0.31049</PDBx:U22>
         <PDBx:U23>-0.05764</PDBx:U23>
         <PDBx:U33>0.32477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2183">
         <PDBx:U11>0.72425</PDBx:U11>
         <PDBx:U12>-0.10640</PDBx:U12>
         <PDBx:U13>0.15849</PDBx:U13>
         <PDBx:U22>0.36379</PDBx:U22>
         <PDBx:U23>-0.05244</PDBx:U23>
         <PDBx:U33>0.35287</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2184">
         <PDBx:U11>0.79873</PDBx:U11>
         <PDBx:U12>-0.10212</PDBx:U12>
         <PDBx:U13>0.14677</PDBx:U13>
         <PDBx:U22>0.43311</PDBx:U22>
         <PDBx:U23>-0.05250</PDBx:U23>
         <PDBx:U33>0.41763</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2185">
         <PDBx:U11>0.92429</PDBx:U11>
         <PDBx:U12>-0.11113</PDBx:U12>
         <PDBx:U13>0.15697</PDBx:U13>
         <PDBx:U22>0.53921</PDBx:U22>
         <PDBx:U23>-0.05769</PDBx:U23>
         <PDBx:U33>0.52176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2186">
         <PDBx:U11>0.89744</PDBx:U11>
         <PDBx:U12>-0.12271</PDBx:U12>
         <PDBx:U13>0.16395</PDBx:U13>
         <PDBx:U22>0.49129</PDBx:U22>
         <PDBx:U23>-0.05832</PDBx:U23>
         <PDBx:U33>0.46907</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2187">
         <PDBx:U11>0.86015</PDBx:U11>
         <PDBx:U12>-0.10696</PDBx:U12>
         <PDBx:U13>0.15844</PDBx:U13>
         <PDBx:U22>0.48010</PDBx:U22>
         <PDBx:U23>-0.06161</PDBx:U23>
         <PDBx:U33>0.46617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2188">
         <PDBx:U11>0.68757</PDBx:U11>
         <PDBx:U12>-0.10487</PDBx:U12>
         <PDBx:U13>0.16486</PDBx:U13>
         <PDBx:U22>0.35799</PDBx:U22>
         <PDBx:U23>-0.04827</PDBx:U23>
         <PDBx:U33>0.35332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2189">
         <PDBx:U11>0.69077</PDBx:U11>
         <PDBx:U12>-0.11063</PDBx:U12>
         <PDBx:U13>0.17698</PDBx:U13>
         <PDBx:U22>0.37097</PDBx:U22>
         <PDBx:U23>-0.04957</PDBx:U23>
         <PDBx:U33>0.36965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2190">
         <PDBx:U11>0.59202</PDBx:U11>
         <PDBx:U12>-0.10003</PDBx:U12>
         <PDBx:U13>0.18133</PDBx:U13>
         <PDBx:U22>0.30921</PDBx:U22>
         <PDBx:U23>-0.04900</PDBx:U23>
         <PDBx:U33>0.31720</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2191">
         <PDBx:U11>0.58531</PDBx:U11>
         <PDBx:U12>-0.10141</PDBx:U12>
         <PDBx:U13>0.19636</PDBx:U13>
         <PDBx:U22>0.32228</PDBx:U22>
         <PDBx:U23>-0.05204</PDBx:U23>
         <PDBx:U33>0.33886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2192">
         <PDBx:U11>0.78455</PDBx:U11>
         <PDBx:U12>-0.11891</PDBx:U12>
         <PDBx:U13>0.16522</PDBx:U13>
         <PDBx:U22>0.44237</PDBx:U22>
         <PDBx:U23>-0.04462</PDBx:U23>
         <PDBx:U33>0.43103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2193">
         <PDBx:U11>0.88287</PDBx:U11>
         <PDBx:U12>-0.12781</PDBx:U12>
         <PDBx:U13>0.17741</PDBx:U13>
         <PDBx:U22>0.54684</PDBx:U22>
         <PDBx:U23>-0.04605</PDBx:U23>
         <PDBx:U33>0.53683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2194">
         <PDBx:U11>0.91664</PDBx:U11>
         <PDBx:U12>-0.14243</PDBx:U12>
         <PDBx:U13>0.18017</PDBx:U13>
         <PDBx:U22>0.54843</PDBx:U22>
         <PDBx:U23>-0.04716</PDBx:U23>
         <PDBx:U33>0.53118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2195">
         <PDBx:U11>0.97050</PDBx:U11>
         <PDBx:U12>-0.15057</PDBx:U12>
         <PDBx:U13>0.18434</PDBx:U13>
         <PDBx:U22>0.60514</PDBx:U22>
         <PDBx:U23>-0.04583</PDBx:U23>
         <PDBx:U33>0.58617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2196">
         <PDBx:U11>1.09182</PDBx:U11>
         <PDBx:U12>-0.15719</PDBx:U12>
         <PDBx:U13>0.20347</PDBx:U13>
         <PDBx:U22>0.74238</PDBx:U22>
         <PDBx:U23>-0.05014</PDBx:U23>
         <PDBx:U33>0.72760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2197">
         <PDBx:U11>1.04786</PDBx:U11>
         <PDBx:U12>-0.15568</PDBx:U12>
         <PDBx:U13>0.22017</PDBx:U13>
         <PDBx:U22>0.71131</PDBx:U22>
         <PDBx:U23>-0.05651</PDBx:U23>
         <PDBx:U33>0.70342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2198">
         <PDBx:U11>1.17265</PDBx:U11>
         <PDBx:U12>-0.16531</PDBx:U12>
         <PDBx:U13>0.20536</PDBx:U13>
         <PDBx:U22>0.82612</PDBx:U22>
         <PDBx:U23>-0.04783</PDBx:U23>
         <PDBx:U33>0.80945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2199">
         <PDBx:U11>0.50452</PDBx:U11>
         <PDBx:U12>-0.08890</PDBx:U12>
         <PDBx:U13>0.16783</PDBx:U13>
         <PDBx:U22>0.23273</PDBx:U22>
         <PDBx:U23>-0.04500</PDBx:U23>
         <PDBx:U33>0.23929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2200">
         <PDBx:U11>0.48813</PDBx:U11>
         <PDBx:U12>-0.07870</PDBx:U12>
         <PDBx:U13>0.16991</PDBx:U13>
         <PDBx:U22>0.25028</PDBx:U22>
         <PDBx:U23>-0.04329</PDBx:U23>
         <PDBx:U33>0.26444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2201">
         <PDBx:U11>0.51520</PDBx:U11>
         <PDBx:U12>-0.06848</PDBx:U12>
         <PDBx:U13>0.17868</PDBx:U13>
         <PDBx:U22>0.29974</PDBx:U22>
         <PDBx:U23>-0.04655</PDBx:U23>
         <PDBx:U33>0.32814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2202">
         <PDBx:U11>0.49934</PDBx:U11>
         <PDBx:U12>-0.06312</PDBx:U12>
         <PDBx:U13>0.18679</PDBx:U13>
         <PDBx:U22>0.31247</PDBx:U22>
         <PDBx:U23>-0.04651</PDBx:U23>
         <PDBx:U33>0.35219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2203">
         <PDBx:U11>0.46425</PDBx:U11>
         <PDBx:U12>-0.07100</PDBx:U12>
         <PDBx:U13>0.15148</PDBx:U13>
         <PDBx:U22>0.22654</PDBx:U22>
         <PDBx:U23>-0.03799</PDBx:U23>
         <PDBx:U33>0.23181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2204">
         <PDBx:U11>0.53087</PDBx:U11>
         <PDBx:U12>-0.08040</PDBx:U12>
         <PDBx:U13>0.14211</PDBx:U13>
         <PDBx:U22>0.27199</PDBx:U22>
         <PDBx:U23>-0.03373</PDBx:U23>
         <PDBx:U33>0.26666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2205">
         <PDBx:U11>0.44357</PDBx:U11>
         <PDBx:U12>-0.05844</PDBx:U12>
         <PDBx:U13>0.14993</PDBx:U13>
         <PDBx:U22>0.24271</PDBx:U22>
         <PDBx:U23>-0.03565</PDBx:U23>
         <PDBx:U33>0.25789</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2206">
         <PDBx:U11>0.60595</PDBx:U11>
         <PDBx:U12>-0.07064</PDBx:U12>
         <PDBx:U13>0.11666</PDBx:U13>
         <PDBx:U22>0.34409</PDBx:U22>
         <PDBx:U23>-0.02895</PDBx:U23>
         <PDBx:U33>0.33487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2207">
         <PDBx:U11>0.51201</PDBx:U11>
         <PDBx:U12>-0.06585</PDBx:U12>
         <PDBx:U13>0.17551</PDBx:U13>
         <PDBx:U22>0.28354</PDBx:U22>
         <PDBx:U23>-0.04872</PDBx:U23>
         <PDBx:U33>0.31232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2208">
         <PDBx:U11>0.52689</PDBx:U11>
         <PDBx:U12>-0.05541</PDBx:U12>
         <PDBx:U13>0.18011</PDBx:U13>
         <PDBx:U22>0.31576</PDBx:U22>
         <PDBx:U23>-0.05058</PDBx:U23>
         <PDBx:U33>0.35837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2209">
         <PDBx:U11>0.63709</PDBx:U11>
         <PDBx:U12>-0.06026</PDBx:U12>
         <PDBx:U13>0.19292</PDBx:U13>
         <PDBx:U22>0.41424</PDBx:U22>
         <PDBx:U23>-0.05642</PDBx:U23>
         <PDBx:U33>0.46440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2210">
         <PDBx:U11>0.62388</PDBx:U11>
         <PDBx:U12>-0.05225</PDBx:U12>
         <PDBx:U13>0.19778</PDBx:U13>
         <PDBx:U22>0.41331</PDBx:U22>
         <PDBx:U23>-0.05800</PDBx:U23>
         <PDBx:U33>0.47703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U33>0.38878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U33>0.39652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
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         <PDBx:U33>0.35404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.07102</PDBx:U23>
         <PDBx:U33>0.31370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.09319</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
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         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
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         <PDBx:U23>-0.06980</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2276">
         <PDBx:U11>0.53411</PDBx:U11>
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         <PDBx:U23>-0.06729</PDBx:U23>
         <PDBx:U33>0.30018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.70135</PDBx:U11>
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         <PDBx:U23>-0.08593</PDBx:U23>
         <PDBx:U33>0.33090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.75732</PDBx:U11>
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         <PDBx:U13>0.10657</PDBx:U13>
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         <PDBx:U23>-0.08531</PDBx:U23>
         <PDBx:U33>0.34574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2279">
         <PDBx:U11>0.73786</PDBx:U11>
         <PDBx:U12>-0.10440</PDBx:U12>
         <PDBx:U13>0.10023</PDBx:U13>
         <PDBx:U22>0.32931</PDBx:U22>
         <PDBx:U23>-0.09220</PDBx:U23>
         <PDBx:U33>0.30950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2280">
         <PDBx:U11>0.79965</PDBx:U11>
         <PDBx:U12>-0.10923</PDBx:U12>
         <PDBx:U13>0.08123</PDBx:U13>
         <PDBx:U22>0.38037</PDBx:U22>
         <PDBx:U23>-0.09108</PDBx:U23>
         <PDBx:U33>0.34718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2281">
         <PDBx:U11>0.77974</PDBx:U11>
         <PDBx:U12>-0.10528</PDBx:U12>
         <PDBx:U13>0.12504</PDBx:U13>
         <PDBx:U22>0.37200</PDBx:U22>
         <PDBx:U23>-0.08506</PDBx:U23>
         <PDBx:U33>0.35136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2282">
         <PDBx:U11>0.69051</PDBx:U11>
         <PDBx:U12>-0.10102</PDBx:U12>
         <PDBx:U13>0.12862</PDBx:U13>
         <PDBx:U22>0.29545</PDBx:U22>
         <PDBx:U23>-0.07829</PDBx:U23>
         <PDBx:U33>0.27663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2283">
         <PDBx:U11>0.88847</PDBx:U11>
         <PDBx:U12>-0.11681</PDBx:U12>
         <PDBx:U13>0.11778</PDBx:U13>
         <PDBx:U22>0.45312</PDBx:U22>
         <PDBx:U23>-0.08497</PDBx:U23>
         <PDBx:U33>0.41491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2284">
         <PDBx:U11>0.71333</PDBx:U11>
         <PDBx:U12>-0.10760</PDBx:U12>
         <PDBx:U13>0.15112</PDBx:U13>
         <PDBx:U22>0.30965</PDBx:U22>
         <PDBx:U23>-0.07991</PDBx:U23>
         <PDBx:U33>0.29383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2285">
         <PDBx:U11>0.75621</PDBx:U11>
         <PDBx:U12>-0.10378</PDBx:U12>
         <PDBx:U13>0.11505</PDBx:U13>
         <PDBx:U22>0.34768</PDBx:U22>
         <PDBx:U23>-0.09937</PDBx:U23>
         <PDBx:U33>0.34195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2286">
         <PDBx:U11>0.84700</PDBx:U11>
         <PDBx:U12>-0.11009</PDBx:U12>
         <PDBx:U13>0.10995</PDBx:U13>
         <PDBx:U22>0.42375</PDBx:U22>
         <PDBx:U23>-0.10695</PDBx:U23>
         <PDBx:U33>0.41703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2287">
         <PDBx:U11>0.91156</PDBx:U11>
         <PDBx:U12>-0.10821</PDBx:U12>
         <PDBx:U13>0.08632</PDBx:U13>
         <PDBx:U22>0.49699</PDBx:U22>
         <PDBx:U23>-0.10654</PDBx:U23>
         <PDBx:U33>0.49003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2288">
         <PDBx:U11>0.89349</PDBx:U11>
         <PDBx:U12>-0.11552</PDBx:U12>
         <PDBx:U13>0.07169</PDBx:U13>
         <PDBx:U22>0.46597</PDBx:U22>
         <PDBx:U23>-0.10961</PDBx:U23>
         <PDBx:U33>0.44870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2289">
         <PDBx:U11>0.93559</PDBx:U11>
         <PDBx:U12>-0.10822</PDBx:U12>
         <PDBx:U13>0.13060</PDBx:U13>
         <PDBx:U22>0.51135</PDBx:U22>
         <PDBx:U23>-0.11437</PDBx:U23>
         <PDBx:U33>0.52344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2290">
         <PDBx:U11>1.12948</PDBx:U11>
         <PDBx:U12>-0.11306</PDBx:U12>
         <PDBx:U13>0.15316</PDBx:U13>
         <PDBx:U22>0.69134</PDBx:U22>
         <PDBx:U23>-0.11749</PDBx:U23>
         <PDBx:U33>0.70237</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2291">
         <PDBx:U11>1.12233</PDBx:U11>
         <PDBx:U12>-0.10620</PDBx:U12>
         <PDBx:U13>0.17571</PDBx:U13>
         <PDBx:U22>0.69297</PDBx:U22>
         <PDBx:U23>-0.12142</PDBx:U23>
         <PDBx:U33>0.72711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.10362</PDBx:U23>
         <PDBx:U33>0.41151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
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         <PDBx:U23>-0.09792</PDBx:U23>
         <PDBx:U33>0.44852</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
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         <PDBx:U23>-0.09973</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2308">
         <PDBx:U11>0.69050</PDBx:U11>
         <PDBx:U12>-0.08403</PDBx:U12>
         <PDBx:U13>-0.00263</PDBx:U13>
         <PDBx:U22>0.32514</PDBx:U22>
         <PDBx:U23>-0.07021</PDBx:U23>
         <PDBx:U33>0.28223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2309">
         <PDBx:U11>0.75501</PDBx:U11>
         <PDBx:U12>-0.09561</PDBx:U12>
         <PDBx:U13>0.03417</PDBx:U13>
         <PDBx:U22>0.36370</PDBx:U22>
         <PDBx:U23>-0.07582</PDBx:U23>
         <PDBx:U33>0.32050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2310">
         <PDBx:U11>0.87486</PDBx:U11>
         <PDBx:U12>-0.09791</PDBx:U12>
         <PDBx:U13>-0.02672</PDBx:U13>
         <PDBx:U22>0.49576</PDBx:U22>
         <PDBx:U23>-0.08204</PDBx:U23>
         <PDBx:U33>0.44786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2311">
         <PDBx:U11>0.95146</PDBx:U11>
         <PDBx:U12>-0.10305</PDBx:U12>
         <PDBx:U13>-0.04770</PDBx:U13>
         <PDBx:U22>0.56090</PDBx:U22>
         <PDBx:U23>-0.08026</PDBx:U23>
         <PDBx:U33>0.49931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2312">
         <PDBx:U11>0.94745</PDBx:U11>
         <PDBx:U12>-0.10013</PDBx:U12>
         <PDBx:U13>-0.05552</PDBx:U13>
         <PDBx:U22>0.54851</PDBx:U22>
         <PDBx:U23>-0.07063</PDBx:U23>
         <PDBx:U33>0.47625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2313">
         <PDBx:U11>0.90429</PDBx:U11>
         <PDBx:U12>-0.10422</PDBx:U12>
         <PDBx:U13>-0.07136</PDBx:U13>
         <PDBx:U22>0.49140</PDBx:U22>
         <PDBx:U23>-0.06786</PDBx:U23>
         <PDBx:U33>0.40833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2314">
         <PDBx:U11>0.96393</PDBx:U11>
         <PDBx:U12>-0.10107</PDBx:U12>
         <PDBx:U13>-0.07010</PDBx:U13>
         <PDBx:U22>0.59110</PDBx:U22>
         <PDBx:U23>-0.08218</PDBx:U23>
         <PDBx:U33>0.53332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2315">
         <PDBx:U11>0.99686</PDBx:U11>
         <PDBx:U12>-0.08993</PDBx:U12>
         <PDBx:U13>-0.07782</PDBx:U13>
         <PDBx:U22>0.64842</PDBx:U22>
         <PDBx:U23>-0.07735</PDBx:U23>
         <PDBx:U33>0.59788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2316">
         <PDBx:U11>1.02746</PDBx:U11>
         <PDBx:U12>-0.08944</PDBx:U12>
         <PDBx:U13>-0.09861</PDBx:U13>
         <PDBx:U22>0.69811</PDBx:U22>
         <PDBx:U23>-0.08011</PDBx:U23>
         <PDBx:U33>0.65242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2317">
         <PDBx:U11>0.96457</PDBx:U11>
         <PDBx:U12>-0.07847</PDBx:U12>
         <PDBx:U13>-0.10903</PDBx:U13>
         <PDBx:U22>0.65808</PDBx:U22>
         <PDBx:U23>-0.07500</PDBx:U23>
         <PDBx:U33>0.61683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2318">
         <PDBx:U11>0.89054</PDBx:U11>
         <PDBx:U12>-0.07087</PDBx:U12>
         <PDBx:U13>-0.12435</PDBx:U13>
         <PDBx:U22>0.58805</PDBx:U22>
         <PDBx:U23>-0.06734</PDBx:U23>
         <PDBx:U33>0.53916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2319">
         <PDBx:U11>0.94596</PDBx:U11>
         <PDBx:U12>-0.07395</PDBx:U12>
         <PDBx:U13>-0.13077</PDBx:U13>
         <PDBx:U22>0.62413</PDBx:U22>
         <PDBx:U23>-0.06347</PDBx:U23>
         <PDBx:U33>0.56399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2320">
         <PDBx:U11>0.81194</PDBx:U11>
         <PDBx:U12>-0.05992</PDBx:U12>
         <PDBx:U13>-0.13280</PDBx:U13>
         <PDBx:U22>0.53115</PDBx:U22>
         <PDBx:U23>-0.06349</PDBx:U23>
         <PDBx:U33>0.48717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2321">
         <PDBx:U11>0.89365</PDBx:U11>
         <PDBx:U12>-0.09337</PDBx:U12>
         <PDBx:U13>-0.04511</PDBx:U13>
         <PDBx:U22>0.50178</PDBx:U22>
         <PDBx:U23>-0.06549</PDBx:U23>
         <PDBx:U33>0.43365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2322">
         <PDBx:U11>0.87766</PDBx:U11>
         <PDBx:U12>-0.09083</PDBx:U12>
         <PDBx:U13>-0.05078</PDBx:U13>
         <PDBx:U22>0.47638</PDBx:U22>
         <PDBx:U23>-0.05640</PDBx:U23>
         <PDBx:U33>0.40166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2323">
         <PDBx:U11>0.94209</PDBx:U11>
         <PDBx:U12>-0.10064</PDBx:U12>
         <PDBx:U13>-0.03512</PDBx:U13>
         <PDBx:U22>0.51402</PDBx:U22>
         <PDBx:U23>-0.05579</PDBx:U23>
         <PDBx:U33>0.43192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2324">
         <PDBx:U11>0.95385</PDBx:U11>
         <PDBx:U12>-0.10095</PDBx:U12>
         <PDBx:U13>-0.01809</PDBx:U13>
         <PDBx:U22>0.52216</PDBx:U22>
         <PDBx:U23>-0.05326</PDBx:U23>
         <PDBx:U33>0.44230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2325">
         <PDBx:U11>0.72144</PDBx:U11>
         <PDBx:U12>-0.08067</PDBx:U12>
         <PDBx:U13>-0.04589</PDBx:U13>
         <PDBx:U22>0.33844</PDBx:U22>
         <PDBx:U23>-0.05222</PDBx:U23>
         <PDBx:U33>0.27170</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2326">
         <PDBx:U11>0.76750</PDBx:U11>
         <PDBx:U12>-0.07098</PDBx:U12>
         <PDBx:U13>-0.06226</PDBx:U13>
         <PDBx:U22>0.40924</PDBx:U22>
         <PDBx:U23>-0.05227</PDBx:U23>
         <PDBx:U33>0.34880</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2327">
         <PDBx:U11>0.84735</PDBx:U11>
         <PDBx:U12>-0.06686</PDBx:U12>
         <PDBx:U13>-0.08752</PDBx:U13>
         <PDBx:U22>0.48739</PDBx:U22>
         <PDBx:U23>-0.04638</PDBx:U23>
         <PDBx:U33>0.42179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2328">
         <PDBx:U11>0.87002</PDBx:U11>
         <PDBx:U12>-0.05555</PDBx:U12>
         <PDBx:U13>-0.10187</PDBx:U13>
         <PDBx:U22>0.53689</PDBx:U22>
         <PDBx:U23>-0.04560</PDBx:U23>
         <PDBx:U33>0.47822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2329">
         <PDBx:U11>0.93860</PDBx:U11>
         <PDBx:U12>-0.04984</PDBx:U12>
         <PDBx:U13>-0.12572</PDBx:U13>
         <PDBx:U22>0.60560</PDBx:U22>
         <PDBx:U23>-0.04000</PDBx:U23>
         <PDBx:U33>0.54450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2330">
         <PDBx:U11>0.90002</PDBx:U11>
         <PDBx:U12>-0.10962</PDBx:U12>
         <PDBx:U13>-0.04106</PDBx:U13>
         <PDBx:U22>0.45281</PDBx:U22>
         <PDBx:U23>-0.05870</PDBx:U23>
         <PDBx:U33>0.36173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2331">
         <PDBx:U11>0.93650</PDBx:U11>
         <PDBx:U12>-0.12017</PDBx:U12>
         <PDBx:U13>-0.02628</PDBx:U13>
         <PDBx:U22>0.46196</PDBx:U22>
         <PDBx:U23>-0.05909</PDBx:U23>
         <PDBx:U33>0.36313</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2332">
         <PDBx:U11>0.96025</PDBx:U11>
         <PDBx:U12>-0.12152</PDBx:U12>
         <PDBx:U13>-0.03197</PDBx:U13>
         <PDBx:U22>0.46774</PDBx:U22>
         <PDBx:U23>-0.04979</PDBx:U23>
         <PDBx:U33>0.36333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2333">
         <PDBx:U11>0.93416</PDBx:U11>
         <PDBx:U12>-0.13005</PDBx:U12>
         <PDBx:U13>-0.01648</PDBx:U13>
         <PDBx:U22>0.42041</PDBx:U22>
         <PDBx:U23>-0.04916</PDBx:U23>
         <PDBx:U33>0.31184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2334">
         <PDBx:U11>1.01095</PDBx:U11>
         <PDBx:U12>-0.12967</PDBx:U12>
         <PDBx:U13>-0.03173</PDBx:U13>
         <PDBx:U22>0.51964</PDBx:U22>
         <PDBx:U23>-0.06534</PDBx:U23>
         <PDBx:U33>0.41207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2335">
         <PDBx:U11>1.01922</PDBx:U11>
         <PDBx:U12>-0.13103</PDBx:U12>
         <PDBx:U13>-0.02033</PDBx:U13>
         <PDBx:U22>0.53822</PDBx:U22>
         <PDBx:U23>-0.07579</PDBx:U23>
         <PDBx:U33>0.43813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2336">
         <PDBx:U11>1.06355</PDBx:U11>
         <PDBx:U12>-0.13130</PDBx:U12>
         <PDBx:U13>0.00905</PDBx:U13>
         <PDBx:U22>0.58378</PDBx:U22>
         <PDBx:U23>-0.07909</PDBx:U23>
         <PDBx:U33>0.49216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2337">
         <PDBx:U11>1.18214</PDBx:U11>
         <PDBx:U12>-0.14044</PDBx:U12>
         <PDBx:U13>0.02324</PDBx:U13>
         <PDBx:U22>0.67668</PDBx:U22>
         <PDBx:U23>-0.07804</PDBx:U23>
         <PDBx:U33>0.57652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2338">
         <PDBx:U11>1.20685</PDBx:U11>
         <PDBx:U12>-0.14286</PDBx:U12>
         <PDBx:U13>0.04946</PDBx:U13>
         <PDBx:U22>0.69838</PDBx:U22>
         <PDBx:U23>-0.08120</PDBx:U23>
         <PDBx:U33>0.60411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2339">
         <PDBx:U11>1.14678</PDBx:U11>
         <PDBx:U12>-0.13579</PDBx:U12>
         <PDBx:U13>0.06363</PDBx:U13>
         <PDBx:U22>0.65943</PDBx:U22>
         <PDBx:U23>-0.08503</PDBx:U23>
         <PDBx:U33>0.58004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2340">
         <PDBx:U11>1.12139</PDBx:U11>
         <PDBx:U12>-0.15251</PDBx:U12>
         <PDBx:U13>0.06153</PDBx:U13>
         <PDBx:U22>0.58850</PDBx:U22>
         <PDBx:U23>-0.08071</PDBx:U23>
         <PDBx:U33>0.48622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2341">
         <PDBx:U11>0.97564</PDBx:U11>
         <PDBx:U12>-0.11331</PDBx:U12>
         <PDBx:U13>-0.05310</PDBx:U13>
         <PDBx:U22>0.49075</PDBx:U22>
         <PDBx:U23>-0.04301</PDBx:U23>
         <PDBx:U33>0.38800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2342">
         <PDBx:U11>1.04323</PDBx:U11>
         <PDBx:U12>-0.11357</PDBx:U12>
         <PDBx:U13>-0.05946</PDBx:U13>
         <PDBx:U22>0.54008</PDBx:U22>
         <PDBx:U23>-0.03420</PDBx:U23>
         <PDBx:U33>0.43570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2343">
         <PDBx:U11>1.06767</PDBx:U11>
         <PDBx:U12>-0.11382</PDBx:U12>
         <PDBx:U13>-0.03894</PDBx:U13>
         <PDBx:U22>0.56449</PDBx:U22>
         <PDBx:U23>-0.03180</PDBx:U23>
         <PDBx:U33>0.46603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2344">
         <PDBx:U11>1.04416</PDBx:U11>
         <PDBx:U12>-0.11921</PDBx:U12>
         <PDBx:U13>-0.03677</PDBx:U13>
         <PDBx:U22>0.51831</PDBx:U22>
         <PDBx:U23>-0.02653</PDBx:U23>
         <PDBx:U33>0.41810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2345">
         <PDBx:U11>0.99677</PDBx:U11>
         <PDBx:U12>-0.10243</PDBx:U12>
         <PDBx:U13>-0.08522</PDBx:U13>
         <PDBx:U22>0.50522</PDBx:U22>
         <PDBx:U23>-0.02853</PDBx:U23>
         <PDBx:U33>0.40517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2346">
         <PDBx:U11>1.05071</PDBx:U11>
         <PDBx:U12>-0.08996</PDBx:U12>
         <PDBx:U13>-0.08593</PDBx:U13>
         <PDBx:U22>0.59159</PDBx:U22>
         <PDBx:U23>-0.02892</PDBx:U23>
         <PDBx:U33>0.50194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2347">
         <PDBx:U11>1.04850</PDBx:U11>
         <PDBx:U12>-0.08052</PDBx:U12>
         <PDBx:U13>-0.10151</PDBx:U13>
         <PDBx:U22>0.59006</PDBx:U22>
         <PDBx:U23>-0.02123</PDBx:U23>
         <PDBx:U33>0.50645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2348">
         <PDBx:U11>0.91657</PDBx:U11>
         <PDBx:U12>-0.06717</PDBx:U12>
         <PDBx:U13>-0.11117</PDBx:U13>
         <PDBx:U22>0.49033</PDBx:U22>
         <PDBx:U23>-0.02205</PDBx:U23>
         <PDBx:U33>0.41509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2349">
         <PDBx:U11>1.02271</PDBx:U11>
         <PDBx:U12>-0.05778</PDBx:U12>
         <PDBx:U13>-0.12976</PDBx:U13>
         <PDBx:U22>0.59373</PDBx:U22>
         <PDBx:U23>-0.01543</PDBx:U23>
         <PDBx:U33>0.52460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2350">
         <PDBx:U11>1.03714</PDBx:U11>
         <PDBx:U12>-0.10871</PDBx:U12>
         <PDBx:U13>-0.02412</PDBx:U13>
         <PDBx:U22>0.55810</PDBx:U22>
         <PDBx:U23>-0.03584</PDBx:U23>
         <PDBx:U33>0.46724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2351">
         <PDBx:U11>0.98518</PDBx:U11>
         <PDBx:U12>-0.10955</PDBx:U12>
         <PDBx:U13>-0.00399</PDBx:U13>
         <PDBx:U22>0.50834</PDBx:U22>
         <PDBx:U23>-0.03453</PDBx:U23>
         <PDBx:U33>0.42315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2352">
         <PDBx:U11>0.85468</PDBx:U11>
         <PDBx:U12>-0.12116</PDBx:U12>
         <PDBx:U13>0.02055</PDBx:U13>
         <PDBx:U22>0.36285</PDBx:U22>
         <PDBx:U23>-0.03962</PDBx:U23>
         <PDBx:U33>0.27524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2353">
         <PDBx:U11>0.96294</PDBx:U11>
         <PDBx:U12>-0.12406</PDBx:U12>
         <PDBx:U13>0.03799</PDBx:U13>
         <PDBx:U22>0.47016</PDBx:U22>
         <PDBx:U23>-0.03899</PDBx:U23>
         <PDBx:U33>0.38712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2354">
         <PDBx:U11>0.72395</PDBx:U11>
         <PDBx:U12>-0.09879</PDBx:U12>
         <PDBx:U13>0.00153</PDBx:U13>
         <PDBx:U22>0.27946</PDBx:U22>
         <PDBx:U23>-0.03675</PDBx:U23>
         <PDBx:U33>0.20399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2355">
         <PDBx:U11>0.81015</PDBx:U11>
         <PDBx:U12>-0.08713</PDBx:U12>
         <PDBx:U13>-0.02021</PDBx:U13>
         <PDBx:U22>0.38133</PDBx:U22>
         <PDBx:U23>-0.03229</PDBx:U23>
         <PDBx:U33>0.30911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2356">
         <PDBx:U11>0.81413</PDBx:U11>
         <PDBx:U12>-0.08468</PDBx:U12>
         <PDBx:U13>-0.03368</PDBx:U13>
         <PDBx:U22>0.37349</PDBx:U22>
         <PDBx:U23>-0.02470</PDBx:U23>
         <PDBx:U33>0.30135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2357">
         <PDBx:U11>0.73622</PDBx:U11>
         <PDBx:U12>-0.07871</PDBx:U12>
         <PDBx:U13>-0.02729</PDBx:U13>
         <PDBx:U22>0.33260</PDBx:U22>
         <PDBx:U23>-0.03625</PDBx:U23>
         <PDBx:U33>0.26493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2358">
         <PDBx:U11>0.88398</PDBx:U11>
         <PDBx:U12>-0.07291</PDBx:U12>
         <PDBx:U13>-0.05315</PDBx:U13>
         <PDBx:U22>0.45793</PDBx:U22>
         <PDBx:U23>-0.02132</PDBx:U23>
         <PDBx:U33>0.39048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2359">
         <PDBx:U11>0.77107</PDBx:U11>
         <PDBx:U12>-0.06809</PDBx:U12>
         <PDBx:U13>-0.04660</PDBx:U13>
         <PDBx:U22>0.38240</PDBx:U22>
         <PDBx:U23>-0.03289</PDBx:U23>
         <PDBx:U33>0.31800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2360">
         <PDBx:U11>0.85306</PDBx:U11>
         <PDBx:U12>-0.06460</PDBx:U12>
         <PDBx:U13>-0.05934</PDBx:U13>
         <PDBx:U22>0.45399</PDBx:U22>
         <PDBx:U23>-0.02552</PDBx:U23>
         <PDBx:U33>0.38968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2361">
         <PDBx:U11>0.86154</PDBx:U11>
         <PDBx:U12>-0.05288</PDBx:U12>
         <PDBx:U13>-0.07774</PDBx:U13>
         <PDBx:U22>0.47811</PDBx:U22>
         <PDBx:U23>-0.02288</PDBx:U23>
         <PDBx:U33>0.41871</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2362">
         <PDBx:U11>0.87227</PDBx:U11>
         <PDBx:U12>-0.12807</PDBx:U12>
         <PDBx:U13>0.02259</PDBx:U13>
         <PDBx:U22>0.36893</PDBx:U22>
         <PDBx:U23>-0.04529</PDBx:U23>
         <PDBx:U33>0.27490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2363">
         <PDBx:U11>0.86847</PDBx:U11>
         <PDBx:U12>-0.13685</PDBx:U12>
         <PDBx:U13>0.04785</PDBx:U13>
         <PDBx:U22>0.35639</PDBx:U22>
         <PDBx:U23>-0.05228</PDBx:U23>
         <PDBx:U33>0.26272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2364">
         <PDBx:U11>0.99598</PDBx:U11>
         <PDBx:U12>-0.14962</PDBx:U12>
         <PDBx:U13>0.04800</PDBx:U13>
         <PDBx:U22>0.45136</PDBx:U22>
         <PDBx:U23>-0.05368</PDBx:U23>
         <PDBx:U33>0.34570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2365">
         <PDBx:U11>1.02277</PDBx:U11>
         <PDBx:U12>-0.15130</PDBx:U12>
         <PDBx:U13>0.02716</PDBx:U13>
         <PDBx:U22>0.46488</PDBx:U22>
         <PDBx:U23>-0.05096</PDBx:U23>
         <PDBx:U33>0.35020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2366">
         <PDBx:U11>0.92672</PDBx:U11>
         <PDBx:U12>-0.13204</PDBx:U12>
         <PDBx:U13>0.05665</PDBx:U13>
         <PDBx:U22>0.43521</PDBx:U22>
         <PDBx:U23>-0.06068</PDBx:U23>
         <PDBx:U33>0.34905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2367">
         <PDBx:U11>0.80898</PDBx:U11>
         <PDBx:U12>-0.12029</PDBx:U12>
         <PDBx:U13>0.05936</PDBx:U13>
         <PDBx:U22>0.34786</PDBx:U22>
         <PDBx:U23>-0.05984</PDBx:U23>
         <PDBx:U33>0.27400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2368">
         <PDBx:U11>0.90652</PDBx:U11>
         <PDBx:U12>-0.11069</PDBx:U12>
         <PDBx:U13>0.03979</PDBx:U13>
         <PDBx:U22>0.46389</PDBx:U22>
         <PDBx:U23>-0.05797</PDBx:U23>
         <PDBx:U33>0.39226</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2369">
         <PDBx:U11>0.80008</PDBx:U11>
         <PDBx:U12>-0.11921</PDBx:U12>
         <PDBx:U13>0.08127</PDBx:U13>
         <PDBx:U22>0.34876</PDBx:U22>
         <PDBx:U23>-0.06112</PDBx:U23>
         <PDBx:U33>0.28443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2370">
         <PDBx:U11>0.87263</PDBx:U11>
         <PDBx:U12>-0.10030</PDBx:U12>
         <PDBx:U13>0.04242</PDBx:U13>
         <PDBx:U22>0.45617</PDBx:U22>
         <PDBx:U23>-0.05726</PDBx:U23>
         <PDBx:U33>0.39518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2371">
         <PDBx:U11>0.79854</PDBx:U11>
         <PDBx:U12>-0.10852</PDBx:U12>
         <PDBx:U13>0.08325</PDBx:U13>
         <PDBx:U22>0.37420</PDBx:U22>
         <PDBx:U23>-0.06011</PDBx:U23>
         <PDBx:U33>0.32067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2372">
         <PDBx:U11>0.84090</PDBx:U11>
         <PDBx:U12>-0.09915</PDBx:U12>
         <PDBx:U13>0.06396</PDBx:U13>
         <PDBx:U22>0.43304</PDBx:U22>
         <PDBx:U23>-0.05809</PDBx:U23>
         <PDBx:U33>0.38062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2373">
         <PDBx:U11>0.93413</PDBx:U11>
         <PDBx:U12>-0.15848</PDBx:U12>
         <PDBx:U13>0.07249</PDBx:U13>
         <PDBx:U22>0.37767</PDBx:U22>
         <PDBx:U23>-0.05853</PDBx:U23>
         <PDBx:U33>0.27270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2374">
         <PDBx:U11>1.05911</PDBx:U11>
         <PDBx:U12>-0.17182</PDBx:U12>
         <PDBx:U13>0.07928</PDBx:U13>
         <PDBx:U22>0.47147</PDBx:U22>
         <PDBx:U23>-0.06178</PDBx:U23>
         <PDBx:U33>0.35561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2375">
         <PDBx:U11>1.07596</PDBx:U11>
         <PDBx:U12>-0.17520</PDBx:U12>
         <PDBx:U13>0.10664</PDBx:U13>
         <PDBx:U22>0.49250</PDBx:U22>
         <PDBx:U23>-0.07192</PDBx:U23>
         <PDBx:U33>0.38293</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2376">
         <PDBx:U11>1.10334</PDBx:U11>
         <PDBx:U12>-0.17485</PDBx:U12>
         <PDBx:U13>0.12671</PDBx:U13>
         <PDBx:U22>0.52920</PDBx:U22>
         <PDBx:U23>-0.07339</PDBx:U23>
         <PDBx:U33>0.42954</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2377">
         <PDBx:U11>1.07882</PDBx:U11>
         <PDBx:U12>-0.18028</PDBx:U12>
         <PDBx:U13>0.08096</PDBx:U13>
         <PDBx:U22>0.46710</PDBx:U22>
         <PDBx:U23>-0.05554</PDBx:U23>
         <PDBx:U33>0.34677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2378">
         <PDBx:U11>1.31440</PDBx:U11>
         <PDBx:U12>-0.19284</PDBx:U12>
         <PDBx:U13>0.07684</PDBx:U13>
         <PDBx:U22>0.66745</PDBx:U22>
         <PDBx:U23>-0.05582</PDBx:U23>
         <PDBx:U33>0.53272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2379">
         <PDBx:U11>1.41890</PDBx:U11>
         <PDBx:U12>-0.20507</PDBx:U12>
         <PDBx:U13>0.09918</PDBx:U13>
         <PDBx:U22>0.75207</PDBx:U22>
         <PDBx:U23>-0.06234</PDBx:U23>
         <PDBx:U33>0.61273</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2380">
         <PDBx:U11>1.37637</PDBx:U11>
         <PDBx:U12>-0.19497</PDBx:U12>
         <PDBx:U13>0.05280</PDBx:U13>
         <PDBx:U22>0.71024</PDBx:U22>
         <PDBx:U23>-0.05050</PDBx:U23>
         <PDBx:U33>0.56478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2381">
         <PDBx:U11>1.41552</PDBx:U11>
         <PDBx:U12>-0.21477</PDBx:U12>
         <PDBx:U13>0.08925</PDBx:U13>
         <PDBx:U22>0.71771</PDBx:U22>
         <PDBx:U23>-0.06091</PDBx:U23>
         <PDBx:U33>0.56400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2382">
         <PDBx:U11>1.42180</PDBx:U11>
         <PDBx:U12>-0.20879</PDBx:U12>
         <PDBx:U13>0.06066</PDBx:U13>
         <PDBx:U22>0.72377</PDBx:U22>
         <PDBx:U23>-0.05352</PDBx:U23>
         <PDBx:U33>0.56635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2383">
         <PDBx:U11>1.08111</PDBx:U11>
         <PDBx:U12>-0.17833</PDBx:U12>
         <PDBx:U13>0.10726</PDBx:U13>
         <PDBx:U22>0.49064</PDBx:U22>
         <PDBx:U23>-0.07940</PDBx:U23>
         <PDBx:U33>0.37654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2384">
         <PDBx:U11>1.07414</PDBx:U11>
         <PDBx:U12>-0.17767</PDBx:U12>
         <PDBx:U13>0.10661</PDBx:U13>
         <PDBx:U22>0.48516</PDBx:U22>
         <PDBx:U23>-0.07935</PDBx:U23>
         <PDBx:U33>0.37151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2385">
         <PDBx:U11>1.05352</PDBx:U11>
         <PDBx:U12>-0.17937</PDBx:U12>
         <PDBx:U13>0.13157</PDBx:U13>
         <PDBx:U22>0.46798</PDBx:U22>
         <PDBx:U23>-0.08993</PDBx:U23>
         <PDBx:U33>0.36264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2386">
         <PDBx:U11>1.05991</PDBx:U11>
         <PDBx:U12>-0.17884</PDBx:U12>
         <PDBx:U13>0.13042</PDBx:U13>
         <PDBx:U22>0.47537</PDBx:U22>
         <PDBx:U23>-0.08991</PDBx:U23>
         <PDBx:U33>0.37014</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2387">
         <PDBx:U11>0.99874</PDBx:U11>
         <PDBx:U12>-0.16634</PDBx:U12>
         <PDBx:U13>0.13677</PDBx:U13>
         <PDBx:U22>0.44721</PDBx:U22>
         <PDBx:U23>-0.09062</PDBx:U23>
         <PDBx:U33>0.35928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2388">
         <PDBx:U11>0.98983</PDBx:U11>
         <PDBx:U12>-0.16608</PDBx:U12>
         <PDBx:U13>0.13667</PDBx:U13>
         <PDBx:U22>0.43892</PDBx:U22>
         <PDBx:U23>-0.09062</PDBx:U23>
         <PDBx:U33>0.35125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2389">
         <PDBx:U11>0.92326</PDBx:U11>
         <PDBx:U12>-0.15750</PDBx:U12>
         <PDBx:U13>0.11793</PDBx:U13>
         <PDBx:U22>0.38909</PDBx:U22>
         <PDBx:U23>-0.08701</PDBx:U23>
         <PDBx:U33>0.30301</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2390">
         <PDBx:U11>0.93407</PDBx:U11>
         <PDBx:U12>-0.15705</PDBx:U12>
         <PDBx:U13>0.11821</PDBx:U13>
         <PDBx:U22>0.40109</PDBx:U22>
         <PDBx:U23>-0.08698</PDBx:U23>
         <PDBx:U33>0.31565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2391">
         <PDBx:U11>1.10893</PDBx:U11>
         <PDBx:U12>-0.18995</PDBx:U12>
         <PDBx:U13>0.15581</PDBx:U13>
         <PDBx:U22>0.50447</PDBx:U22>
         <PDBx:U23>-0.09344</PDBx:U23>
         <PDBx:U33>0.39797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2392">
         <PDBx:U11>1.11253</PDBx:U11>
         <PDBx:U12>-0.18999</PDBx:U12>
         <PDBx:U13>0.15371</PDBx:U13>
         <PDBx:U22>0.50717</PDBx:U22>
         <PDBx:U23>-0.09343</PDBx:U23>
         <PDBx:U33>0.39959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2393">
         <PDBx:U11>1.19207</PDBx:U11>
         <PDBx:U12>-0.20322</PDBx:U12>
         <PDBx:U13>0.15386</PDBx:U13>
         <PDBx:U22>0.55297</PDBx:U22>
         <PDBx:U23>-0.09572</PDBx:U23>
         <PDBx:U33>0.42958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2394">
         <PDBx:U11>1.18540</PDBx:U11>
         <PDBx:U12>-0.20259</PDBx:U12>
         <PDBx:U13>0.14576</PDBx:U13>
         <PDBx:U22>0.54567</PDBx:U22>
         <PDBx:U23>-0.09182</PDBx:U23>
         <PDBx:U33>0.41996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2395">
         <PDBx:U11>1.20770</PDBx:U11>
         <PDBx:U12>-0.21087</PDBx:U12>
         <PDBx:U13>0.14165</PDBx:U13>
         <PDBx:U22>0.54577</PDBx:U22>
         <PDBx:U23>-0.08806</PDBx:U23>
         <PDBx:U33>0.40967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2396">
         <PDBx:U11>1.21028</PDBx:U11>
         <PDBx:U12>-0.20427</PDBx:U12>
         <PDBx:U13>0.12288</PDBx:U13>
         <PDBx:U22>0.55855</PDBx:U22>
         <PDBx:U23>-0.09068</PDBx:U23>
         <PDBx:U33>0.42035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2397">
         <PDBx:U11>1.23933</PDBx:U11>
         <PDBx:U12>-0.21020</PDBx:U12>
         <PDBx:U13>0.16231</PDBx:U13>
         <PDBx:U22>0.58325</PDBx:U22>
         <PDBx:U23>-0.10499</PDBx:U23>
         <PDBx:U33>0.45378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2398">
         <PDBx:U11>1.22792</PDBx:U11>
         <PDBx:U12>-0.21434</PDBx:U12>
         <PDBx:U13>0.15708</PDBx:U13>
         <PDBx:U22>0.56308</PDBx:U22>
         <PDBx:U23>-0.09128</PDBx:U23>
         <PDBx:U33>0.42984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2399">
         <PDBx:U11>1.28318</PDBx:U11>
         <PDBx:U12>-0.22216</PDBx:U12>
         <PDBx:U13>0.14253</PDBx:U13>
         <PDBx:U22>0.59209</PDBx:U22>
         <PDBx:U23>-0.09218</PDBx:U23>
         <PDBx:U33>0.44191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2400">
         <PDBx:U11>1.26105</PDBx:U11>
         <PDBx:U12>-0.21611</PDBx:U12>
         <PDBx:U13>0.12007</PDBx:U13>
         <PDBx:U22>0.57765</PDBx:U22>
         <PDBx:U23>-0.08900</PDBx:U23>
         <PDBx:U33>0.42469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2401">
         <PDBx:U11>1.27582</PDBx:U11>
         <PDBx:U12>-0.22210</PDBx:U12>
         <PDBx:U13>0.15507</PDBx:U13>
         <PDBx:U22>0.58791</PDBx:U22>
         <PDBx:U23>-0.10270</PDBx:U23>
         <PDBx:U33>0.44083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2402">
         <PDBx:U11>1.28117</PDBx:U11>
         <PDBx:U12>-0.22265</PDBx:U12>
         <PDBx:U13>0.14097</PDBx:U13>
         <PDBx:U22>0.58847</PDBx:U22>
         <PDBx:U23>-0.08931</PDBx:U23>
         <PDBx:U33>0.43802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2403">
         <PDBx:U11>0.94347</PDBx:U11>
         <PDBx:U12>-0.16468</PDBx:U12>
         <PDBx:U13>0.16140</PDBx:U13>
         <PDBx:U22>0.40230</PDBx:U22>
         <PDBx:U23>-0.09528</PDBx:U23>
         <PDBx:U33>0.32785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2404">
         <PDBx:U11>0.99261</PDBx:U11>
         <PDBx:U12>-0.15238</PDBx:U12>
         <PDBx:U13>0.16740</PDBx:U13>
         <PDBx:U22>0.48223</PDBx:U22>
         <PDBx:U23>-0.09616</PDBx:U23>
         <PDBx:U33>0.42542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2405">
         <PDBx:U11>1.03283</PDBx:U11>
         <PDBx:U12>-0.14591</PDBx:U12>
         <PDBx:U13>0.16375</PDBx:U13>
         <PDBx:U22>0.54102</PDBx:U22>
         <PDBx:U23>-0.08801</PDBx:U23>
         <PDBx:U33>0.48920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2406">
         <PDBx:U11>1.03317</PDBx:U11>
         <PDBx:U12>-0.13561</PDBx:U12>
         <PDBx:U13>0.16805</PDBx:U13>
         <PDBx:U22>0.56695</PDBx:U22>
         <PDBx:U23>-0.08816</PDBx:U23>
         <PDBx:U33>0.52916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2407">
         <PDBx:U11>0.99711</PDBx:U11>
         <PDBx:U12>-0.15219</PDBx:U12>
         <PDBx:U13>0.19486</PDBx:U13>
         <PDBx:U22>0.49044</PDBx:U22>
         <PDBx:U23>-0.10514</PDBx:U23>
         <PDBx:U33>0.44845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2408">
         <PDBx:U11>1.19896</PDBx:U11>
         <PDBx:U12>-0.16133</PDBx:U12>
         <PDBx:U13>0.21425</PDBx:U13>
         <PDBx:U22>0.67864</PDBx:U22>
         <PDBx:U23>-0.10673</PDBx:U23>
         <PDBx:U33>0.63525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2409">
         <PDBx:U11>1.24390</PDBx:U11>
         <PDBx:U12>-0.17152</PDBx:U12>
         <PDBx:U13>0.20772</PDBx:U13>
         <PDBx:U22>0.70063</PDBx:U22>
         <PDBx:U23>-0.10329</PDBx:U23>
         <PDBx:U33>0.64151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2410">
         <PDBx:U11>1.25565</PDBx:U11>
         <PDBx:U12>-0.15832</PDBx:U12>
         <PDBx:U13>0.23562</PDBx:U13>
         <PDBx:U22>0.74732</PDBx:U22>
         <PDBx:U23>-0.11159</PDBx:U23>
         <PDBx:U33>0.71935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2411">
         <PDBx:U11>0.96158</PDBx:U11>
         <PDBx:U12>-0.15152</PDBx:U12>
         <PDBx:U13>0.15581</PDBx:U13>
         <PDBx:U22>0.45681</PDBx:U22>
         <PDBx:U23>-0.08106</PDBx:U23>
         <PDBx:U33>0.39491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2412">
         <PDBx:U11>0.97396</PDBx:U11>
         <PDBx:U12>-0.14711</PDBx:U12>
         <PDBx:U13>0.15692</PDBx:U13>
         <PDBx:U22>0.48398</PDBx:U22>
         <PDBx:U23>-0.07511</PDBx:U23>
         <PDBx:U33>0.42834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2413">
         <PDBx:U11>0.96920</PDBx:U11>
         <PDBx:U12>-0.14594</PDBx:U12>
         <PDBx:U13>0.13249</PDBx:U13>
         <PDBx:U22>0.47314</PDBx:U22>
         <PDBx:U23>-0.06555</PDBx:U23>
         <PDBx:U33>0.40753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2414">
         <PDBx:U11>0.93759</PDBx:U11>
         <PDBx:U12>-0.15007</PDBx:U12>
         <PDBx:U13>0.11582</PDBx:U13>
         <PDBx:U22>0.42273</PDBx:U22>
         <PDBx:U23>-0.06301</PDBx:U23>
         <PDBx:U33>0.34510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2415">
         <PDBx:U11>1.10255</PDBx:U11>
         <PDBx:U12>-0.15566</PDBx:U12>
         <PDBx:U13>0.17935</PDBx:U13>
         <PDBx:U22>0.60391</PDBx:U22>
         <PDBx:U23>-0.07794</PDBx:U23>
         <PDBx:U33>0.55234</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2416">
         <PDBx:U11>1.19417</PDBx:U11>
         <PDBx:U12>-0.15163</PDBx:U12>
         <PDBx:U13>0.20334</PDBx:U13>
         <PDBx:U22>0.71339</PDBx:U22>
         <PDBx:U23>-0.08603</PDBx:U23>
         <PDBx:U33>0.67845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2417">
         <PDBx:U11>1.27627</PDBx:U11>
         <PDBx:U12>-0.16181</PDBx:U12>
         <PDBx:U13>0.22554</PDBx:U13>
         <PDBx:U22>0.78304</PDBx:U22>
         <PDBx:U23>-0.09118</PDBx:U23>
         <PDBx:U33>0.74996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2418">
         <PDBx:U11>1.36761</PDBx:U11>
         <PDBx:U12>-0.17366</PDBx:U12>
         <PDBx:U13>0.22843</PDBx:U13>
         <PDBx:U22>0.84335</PDBx:U22>
         <PDBx:U23>-0.09497</PDBx:U23>
         <PDBx:U33>0.79731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2419">
         <PDBx:U11>1.46030</PDBx:U11>
         <PDBx:U12>-0.18492</PDBx:U12>
         <PDBx:U13>0.24568</PDBx:U13>
         <PDBx:U22>0.91824</PDBx:U22>
         <PDBx:U23>-0.09954</PDBx:U23>
         <PDBx:U33>0.86895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2420">
         <PDBx:U11>1.46285</PDBx:U11>
         <PDBx:U12>-0.18579</PDBx:U12>
         <PDBx:U13>0.26136</PDBx:U13>
         <PDBx:U22>0.93255</PDBx:U22>
         <PDBx:U23>-0.10121</PDBx:U23>
         <PDBx:U33>0.89245</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2421">
         <PDBx:U11>1.47693</PDBx:U11>
         <PDBx:U12>-0.19548</PDBx:U12>
         <PDBx:U13>0.24705</PDBx:U13>
         <PDBx:U22>0.90580</PDBx:U22>
         <PDBx:U23>-0.10285</PDBx:U23>
         <PDBx:U33>0.84330</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2422">
         <PDBx:U11>0.92856</PDBx:U11>
         <PDBx:U12>-0.13957</PDBx:U12>
         <PDBx:U13>0.13005</PDBx:U13>
         <PDBx:U22>0.44908</PDBx:U22>
         <PDBx:U23>-0.06046</PDBx:U23>
         <PDBx:U33>0.38974</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2423">
         <PDBx:U11>0.88039</PDBx:U11>
         <PDBx:U12>-0.13661</PDBx:U12>
         <PDBx:U13>0.10760</PDBx:U13>
         <PDBx:U22>0.39674</PDBx:U22>
         <PDBx:U23>-0.05159</PDBx:U23>
         <PDBx:U33>0.33120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2424">
         <PDBx:U11>0.91579</PDBx:U11>
         <PDBx:U12>-0.14864</PDBx:U12>
         <PDBx:U13>0.10420</PDBx:U13>
         <PDBx:U22>0.39921</PDBx:U22>
         <PDBx:U23>-0.04800</PDBx:U23>
         <PDBx:U33>0.32427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2425">
         <PDBx:U11>0.94890</PDBx:U11>
         <PDBx:U12>-0.15834</PDBx:U12>
         <PDBx:U13>0.12255</PDBx:U13>
         <PDBx:U22>0.41998</PDBx:U22>
         <PDBx:U23>-0.05083</PDBx:U23>
         <PDBx:U33>0.34639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2426">
         <PDBx:U11>0.87002</PDBx:U11>
         <PDBx:U12>-0.12894</PDBx:U12>
         <PDBx:U13>0.10916</PDBx:U13>
         <PDBx:U22>0.40793</PDBx:U22>
         <PDBx:U23>-0.04810</PDBx:U23>
         <PDBx:U33>0.35126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2427">
         <PDBx:U11>0.87347</PDBx:U11>
         <PDBx:U12>-0.12264</PDBx:U12>
         <PDBx:U13>0.08561</PDBx:U13>
         <PDBx:U22>0.41178</PDBx:U22>
         <PDBx:U23>-0.03965</PDBx:U23>
         <PDBx:U33>0.35174</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2428">
         <PDBx:U11>0.86105</PDBx:U11>
         <PDBx:U12>-0.11074</PDBx:U12>
         <PDBx:U13>0.06728</PDBx:U13>
         <PDBx:U22>0.41786</PDBx:U22>
         <PDBx:U23>-0.03909</PDBx:U23>
         <PDBx:U33>0.35741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2429">
         <PDBx:U11>0.78823</PDBx:U11>
         <PDBx:U12>-0.11987</PDBx:U12>
         <PDBx:U13>0.09165</PDBx:U13>
         <PDBx:U22>0.33879</PDBx:U22>
         <PDBx:U23>-0.03707</PDBx:U23>
         <PDBx:U33>0.28597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2430">
         <PDBx:U11>0.91458</PDBx:U11>
         <PDBx:U12>-0.14785</PDBx:U12>
         <PDBx:U13>0.08042</PDBx:U13>
         <PDBx:U22>0.38386</PDBx:U22>
         <PDBx:U23>-0.04219</PDBx:U23>
         <PDBx:U33>0.30036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2431">
         <PDBx:U11>0.95599</PDBx:U11>
         <PDBx:U12>-0.15883</PDBx:U12>
         <PDBx:U13>0.07440</PDBx:U13>
         <PDBx:U22>0.39106</PDBx:U22>
         <PDBx:U23>-0.03838</PDBx:U23>
         <PDBx:U33>0.29885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2432">
         <PDBx:U11>0.99769</PDBx:U11>
         <PDBx:U12>-0.15778</PDBx:U12>
         <PDBx:U13>0.06741</PDBx:U13>
         <PDBx:U22>0.42789</PDBx:U22>
         <PDBx:U23>-0.03128</PDBx:U23>
         <PDBx:U33>0.34019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2433">
         <PDBx:U11>0.99079</PDBx:U11>
         <PDBx:U12>-0.15191</PDBx:U12>
         <PDBx:U13>0.04456</PDBx:U13>
         <PDBx:U22>0.41609</PDBx:U22>
         <PDBx:U23>-0.02442</PDBx:U23>
         <PDBx:U33>0.32768</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2434">
         <PDBx:U11>1.08297</PDBx:U11>
         <PDBx:U12>-0.15834</PDBx:U12>
         <PDBx:U13>0.05172</PDBx:U13>
         <PDBx:U22>0.50438</PDBx:U22>
         <PDBx:U23>-0.03607</PDBx:U23>
         <PDBx:U33>0.40222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2435">
         <PDBx:U11>1.20426</PDBx:U11>
         <PDBx:U12>-0.16869</PDBx:U12>
         <PDBx:U13>0.04319</PDBx:U13>
         <PDBx:U22>0.58943</PDBx:U22>
         <PDBx:U23>-0.03129</PDBx:U23>
         <PDBx:U33>0.47890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2436">
         <PDBx:U11>1.24790</PDBx:U11>
         <PDBx:U12>-0.18114</PDBx:U12>
         <PDBx:U13>0.06146</PDBx:U13>
         <PDBx:U22>0.61298</PDBx:U22>
         <PDBx:U23>-0.03448</PDBx:U23>
         <PDBx:U33>0.49904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2437">
         <PDBx:U11>1.20731</PDBx:U11>
         <PDBx:U12>-0.16422</PDBx:U12>
         <PDBx:U13>0.01862</PDBx:U13>
         <PDBx:U22>0.58415</PDBx:U22>
         <PDBx:U23>-0.02477</PDBx:U23>
         <PDBx:U33>0.47128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01976</PDBx:U23>
         <PDBx:U33>0.27761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02533</PDBx:U23>
         <PDBx:U33>0.29853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.30864</PDBx:U22>
         <PDBx:U23>-0.01482</PDBx:U23>
         <PDBx:U33>0.24757</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01262</PDBx:U23>
         <PDBx:U33>0.26823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.00899</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.34236</PDBx:U22>
         <PDBx:U23>-0.00780</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>1.00109</PDBx:U11>
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         <PDBx:U13>0.08173</PDBx:U13>
         <PDBx:U22>0.38472</PDBx:U22>
         <PDBx:U23>-0.02397</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>1.00606</PDBx:U11>
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         <PDBx:U13>0.09144</PDBx:U13>
         <PDBx:U22>0.36184</PDBx:U22>
         <PDBx:U23>-0.02489</PDBx:U23>
         <PDBx:U33>0.27921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2454">
         <PDBx:U11>1.04908</PDBx:U11>
         <PDBx:U12>-0.19352</PDBx:U12>
         <PDBx:U13>0.09942</PDBx:U13>
         <PDBx:U22>0.41950</PDBx:U22>
         <PDBx:U23>-0.02572</PDBx:U23>
         <PDBx:U33>0.34487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2455">
         <PDBx:U11>1.03065</PDBx:U11>
         <PDBx:U12>-0.18678</PDBx:U12>
         <PDBx:U13>0.08266</PDBx:U13>
         <PDBx:U22>0.40126</PDBx:U22>
         <PDBx:U23>-0.02009</PDBx:U23>
         <PDBx:U33>0.33122</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2456">
         <PDBx:U11>1.08831</PDBx:U11>
         <PDBx:U12>-0.19810</PDBx:U12>
         <PDBx:U13>0.07005</PDBx:U13>
         <PDBx:U22>0.40916</PDBx:U22>
         <PDBx:U23>-0.01792</PDBx:U23>
         <PDBx:U33>0.32052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2457">
         <PDBx:U11>1.21812</PDBx:U11>
         <PDBx:U12>-0.21387</PDBx:U12>
         <PDBx:U13>0.07944</PDBx:U13>
         <PDBx:U22>0.50790</PDBx:U22>
         <PDBx:U23>-0.01863</PDBx:U23>
         <PDBx:U33>0.41425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2458">
         <PDBx:U11>1.13755</PDBx:U11>
         <PDBx:U12>-0.22272</PDBx:U12>
         <PDBx:U13>0.10401</PDBx:U13>
         <PDBx:U22>0.43352</PDBx:U22>
         <PDBx:U23>-0.02531</PDBx:U23>
         <PDBx:U33>0.33959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2459">
         <PDBx:U11>1.22409</PDBx:U11>
         <PDBx:U12>-0.21706</PDBx:U12>
         <PDBx:U13>0.06196</PDBx:U13>
         <PDBx:U22>0.48389</PDBx:U22>
         <PDBx:U23>-0.01263</PDBx:U23>
         <PDBx:U33>0.38651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2460">
         <PDBx:U11>0.99092</PDBx:U11>
         <PDBx:U12>-0.20003</PDBx:U12>
         <PDBx:U13>0.12500</PDBx:U13>
         <PDBx:U22>0.37458</PDBx:U22>
         <PDBx:U23>-0.03334</PDBx:U23>
         <PDBx:U33>0.30165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2461">
         <PDBx:U11>1.03022</PDBx:U11>
         <PDBx:U12>-0.19908</PDBx:U12>
         <PDBx:U13>0.13413</PDBx:U13>
         <PDBx:U22>0.43352</PDBx:U22>
         <PDBx:U23>-0.03520</PDBx:U23>
         <PDBx:U33>0.36691</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2462">
         <PDBx:U11>0.99631</PDBx:U11>
         <PDBx:U12>-0.20873</PDBx:U12>
         <PDBx:U13>0.12972</PDBx:U13>
         <PDBx:U22>0.37523</PDBx:U22>
         <PDBx:U23>-0.03219</PDBx:U23>
         <PDBx:U33>0.30491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2463">
         <PDBx:U11>0.98343</PDBx:U11>
         <PDBx:U12>-0.20702</PDBx:U12>
         <PDBx:U13>0.13093</PDBx:U13>
         <PDBx:U22>0.37617</PDBx:U22>
         <PDBx:U23>-0.03184</PDBx:U23>
         <PDBx:U33>0.30965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2464">
         <PDBx:U11>1.09713</PDBx:U11>
         <PDBx:U12>-0.20277</PDBx:U12>
         <PDBx:U13>0.16243</PDBx:U13>
         <PDBx:U22>0.52293</PDBx:U22>
         <PDBx:U23>-0.04439</PDBx:U23>
         <PDBx:U33>0.45946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2465">
         <PDBx:U11>1.18968</PDBx:U11>
         <PDBx:U12>-0.18950</PDBx:U12>
         <PDBx:U13>0.16624</PDBx:U13>
         <PDBx:U22>0.65015</PDBx:U22>
         <PDBx:U23>-0.04706</PDBx:U23>
         <PDBx:U33>0.59501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2466">
         <PDBx:U11>1.34661</PDBx:U11>
         <PDBx:U12>-0.19155</PDBx:U12>
         <PDBx:U13>0.19321</PDBx:U13>
         <PDBx:U22>0.82862</PDBx:U22>
         <PDBx:U23>-0.05620</PDBx:U23>
         <PDBx:U33>0.77923</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2467">
         <PDBx:U11>1.40910</PDBx:U11>
         <PDBx:U12>-0.20334</PDBx:U12>
         <PDBx:U13>0.20969</PDBx:U13>
         <PDBx:U22>0.88124</PDBx:U22>
         <PDBx:U23>-0.06055</PDBx:U23>
         <PDBx:U33>0.82874</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2468">
         <PDBx:U11>1.35036</PDBx:U11>
         <PDBx:U12>-0.18086</PDBx:U12>
         <PDBx:U13>0.19772</PDBx:U13>
         <PDBx:U22>0.85950</PDBx:U22>
         <PDBx:U23>-0.05890</PDBx:U23>
         <PDBx:U33>0.81827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2469">
         <PDBx:U11>1.05746</PDBx:U11>
         <PDBx:U12>-0.21884</PDBx:U12>
         <PDBx:U13>0.12421</PDBx:U13>
         <PDBx:U22>0.40040</PDBx:U22>
         <PDBx:U23>-0.02980</PDBx:U23>
         <PDBx:U33>0.32200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2470">
         <PDBx:U11>1.09524</PDBx:U11>
         <PDBx:U12>-0.22944</PDBx:U12>
         <PDBx:U13>0.12149</PDBx:U13>
         <PDBx:U22>0.41182</PDBx:U22>
         <PDBx:U23>-0.02711</PDBx:U23>
         <PDBx:U33>0.32885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2471">
         <PDBx:U11>1.12357</PDBx:U11>
         <PDBx:U12>-0.22379</PDBx:U12>
         <PDBx:U13>0.09238</PDBx:U13>
         <PDBx:U22>0.41702</PDBx:U22>
         <PDBx:U23>-0.01836</PDBx:U23>
         <PDBx:U33>0.33548</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2472">
         <PDBx:U11>1.12951</PDBx:U11>
         <PDBx:U12>-0.23166</PDBx:U12>
         <PDBx:U13>0.08719</PDBx:U13>
         <PDBx:U22>0.39792</PDBx:U22>
         <PDBx:U23>-0.01533</PDBx:U23>
         <PDBx:U33>0.31311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2473">
         <PDBx:U11>1.22909</PDBx:U11>
         <PDBx:U12>-0.24591</PDBx:U12>
         <PDBx:U13>0.13765</PDBx:U13>
         <PDBx:U22>0.51987</PDBx:U22>
         <PDBx:U23>-0.03072</PDBx:U23>
         <PDBx:U33>0.42648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2474">
         <PDBx:U11>1.38547</PDBx:U11>
         <PDBx:U12>-0.25184</PDBx:U12>
         <PDBx:U13>0.16763</PDBx:U13>
         <PDBx:U22>0.69857</PDBx:U22>
         <PDBx:U23>-0.03982</PDBx:U23>
         <PDBx:U33>0.60522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2475">
         <PDBx:U11>1.38656</PDBx:U11>
         <PDBx:U12>-0.24850</PDBx:U12>
         <PDBx:U13>0.17987</PDBx:U13>
         <PDBx:U22>0.73199</PDBx:U22>
         <PDBx:U23>-0.04311</PDBx:U23>
         <PDBx:U33>0.64529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2476">
         <PDBx:U11>1.44170</PDBx:U11>
         <PDBx:U12>-0.25977</PDBx:U12>
         <PDBx:U13>0.18748</PDBx:U13>
         <PDBx:U22>0.75111</PDBx:U22>
         <PDBx:U23>-0.04643</PDBx:U23>
         <PDBx:U33>0.65282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2477">
         <PDBx:U11>1.37402</PDBx:U11>
         <PDBx:U12>-0.25361</PDBx:U12>
         <PDBx:U13>0.20565</PDBx:U13>
         <PDBx:U22>0.73565</PDBx:U22>
         <PDBx:U23>-0.05112</PDBx:U23>
         <PDBx:U33>0.64925</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2478">
         <PDBx:U11>1.44198</PDBx:U11>
         <PDBx:U12>-0.26038</PDBx:U12>
         <PDBx:U13>0.21116</PDBx:U13>
         <PDBx:U22>0.78168</PDBx:U22>
         <PDBx:U23>-0.05364</PDBx:U23>
         <PDBx:U33>0.68858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2479">
         <PDBx:U11>1.08024</PDBx:U11>
         <PDBx:U12>-0.20983</PDBx:U12>
         <PDBx:U13>0.07351</PDBx:U13>
         <PDBx:U22>0.38271</PDBx:U22>
         <PDBx:U23>-0.01426</PDBx:U23>
         <PDBx:U33>0.30636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2480">
         <PDBx:U11>1.06913</PDBx:U11>
         <PDBx:U12>-0.20103</PDBx:U12>
         <PDBx:U13>0.04563</PDBx:U13>
         <PDBx:U22>0.35670</PDBx:U22>
         <PDBx:U23>-0.00661</PDBx:U23>
         <PDBx:U33>0.28480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2481">
         <PDBx:U11>1.03429</PDBx:U11>
         <PDBx:U12>-0.19337</PDBx:U12>
         <PDBx:U13>0.04057</PDBx:U13>
         <PDBx:U22>0.33857</PDBx:U22>
         <PDBx:U23>-0.00567</PDBx:U23>
         <PDBx:U33>0.27496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2482">
         <PDBx:U11>1.00135</PDBx:U11>
         <PDBx:U12>-0.19364</PDBx:U12>
         <PDBx:U13>0.05715</PDBx:U13>
         <PDBx:U22>0.33213</PDBx:U22>
         <PDBx:U23>-0.01032</PDBx:U23>
         <PDBx:U33>0.27014</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2483">
         <PDBx:U11>1.07729</PDBx:U11>
         <PDBx:U12>-0.18787</PDBx:U12>
         <PDBx:U13>0.02851</PDBx:U13>
         <PDBx:U22>0.37453</PDBx:U22>
         <PDBx:U23>-0.00317</PDBx:U23>
         <PDBx:U33>0.30472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2484">
         <PDBx:U11>1.02975</PDBx:U11>
         <PDBx:U12>-0.17442</PDBx:U12>
         <PDBx:U13>0.02876</PDBx:U13>
         <PDBx:U22>0.36422</PDBx:U22>
         <PDBx:U23>-0.00422</PDBx:U23>
         <PDBx:U33>0.30166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2485">
         <PDBx:U11>1.04318</PDBx:U11>
         <PDBx:U12>-0.18584</PDBx:U12>
         <PDBx:U13>0.01685</PDBx:U13>
         <PDBx:U22>0.33219</PDBx:U22>
         <PDBx:U23>0.00020</PDBx:U23>
         <PDBx:U33>0.27386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2486">
         <PDBx:U11>1.01157</PDBx:U11>
         <PDBx:U12>-0.17659</PDBx:U12>
         <PDBx:U13>0.00861</PDBx:U13>
         <PDBx:U22>0.31498</PDBx:U22>
         <PDBx:U23>0.00124</PDBx:U23>
         <PDBx:U33>0.26466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2487">
         <PDBx:U11>0.96124</PDBx:U11>
         <PDBx:U12>-0.16479</PDBx:U12>
         <PDBx:U13>0.01407</PDBx:U13>
         <PDBx:U22>0.30533</PDBx:U22>
         <PDBx:U23>-0.00112</PDBx:U23>
         <PDBx:U33>0.26029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2488">
         <PDBx:U11>0.92207</PDBx:U11>
         <PDBx:U12>-0.16530</PDBx:U12>
         <PDBx:U13>0.02562</PDBx:U13>
         <PDBx:U22>0.28675</PDBx:U22>
         <PDBx:U23>-0.00420</PDBx:U23>
         <PDBx:U33>0.24253</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2489">
         <PDBx:U11>1.02665</PDBx:U11>
         <PDBx:U12>-0.16623</PDBx:U12>
         <PDBx:U13>-0.01970</PDBx:U13>
         <PDBx:U22>0.31088</PDBx:U22>
         <PDBx:U23>0.00727</PDBx:U23>
         <PDBx:U33>0.26752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2490">
         <PDBx:U11>1.05659</PDBx:U11>
         <PDBx:U12>-0.15525</PDBx:U12>
         <PDBx:U13>-0.02863</PDBx:U13>
         <PDBx:U22>0.35619</PDBx:U22>
         <PDBx:U23>0.00767</PDBx:U23>
         <PDBx:U33>0.32110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2491">
         <PDBx:U11>0.97898</PDBx:U11>
         <PDBx:U12>-0.15418</PDBx:U12>
         <PDBx:U13>0.00565</PDBx:U13>
         <PDBx:U22>0.33605</PDBx:U22>
         <PDBx:U23>0.00066</PDBx:U23>
         <PDBx:U33>0.29318</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2492">
         <PDBx:U11>0.98664</PDBx:U11>
         <PDBx:U12>-0.14295</PDBx:U12>
         <PDBx:U13>0.01064</PDBx:U13>
         <PDBx:U22>0.38175</PDBx:U22>
         <PDBx:U23>-0.00095</PDBx:U23>
         <PDBx:U33>0.34241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2493">
         <PDBx:U11>0.85661</PDBx:U11>
         <PDBx:U12>-0.15173</PDBx:U12>
         <PDBx:U13>0.03814</PDBx:U13>
         <PDBx:U22>0.27033</PDBx:U22>
         <PDBx:U23>-0.00745</PDBx:U23>
         <PDBx:U33>0.22654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2494">
         <PDBx:U11>0.82842</PDBx:U11>
         <PDBx:U12>-0.14681</PDBx:U12>
         <PDBx:U13>0.04716</PDBx:U13>
         <PDBx:U22>0.27064</PDBx:U22>
         <PDBx:U23>-0.00989</PDBx:U23>
         <PDBx:U33>0.22987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2495">
         <PDBx:U11>0.88595</PDBx:U11>
         <PDBx:U12>-0.13135</PDBx:U12>
         <PDBx:U13>-0.00295</PDBx:U13>
         <PDBx:U22>0.29128</PDBx:U22>
         <PDBx:U23>0.00178</PDBx:U23>
         <PDBx:U33>0.25174</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2496">
         <PDBx:U11>0.89163</PDBx:U11>
         <PDBx:U12>-0.16444</PDBx:U12>
         <PDBx:U13>0.05178</PDBx:U13>
         <PDBx:U22>0.28954</PDBx:U22>
         <PDBx:U23>-0.01069</PDBx:U23>
         <PDBx:U33>0.23885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2497">
         <PDBx:U11>0.92992</PDBx:U11>
         <PDBx:U12>-0.17188</PDBx:U12>
         <PDBx:U13>0.07860</PDBx:U13>
         <PDBx:U22>0.34555</PDBx:U22>
         <PDBx:U23>-0.01804</PDBx:U23>
         <PDBx:U33>0.29236</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2498">
         <PDBx:U11>0.87638</PDBx:U11>
         <PDBx:U12>-0.17816</PDBx:U12>
         <PDBx:U13>0.09269</PDBx:U13>
         <PDBx:U22>0.30205</PDBx:U22>
         <PDBx:U23>-0.02144</PDBx:U23>
         <PDBx:U33>0.24952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2499">
         <PDBx:U11>0.84083</PDBx:U11>
         <PDBx:U12>-0.17518</PDBx:U12>
         <PDBx:U13>0.10773</PDBx:U13>
         <PDBx:U22>0.29750</PDBx:U22>
         <PDBx:U23>-0.02574</PDBx:U23>
         <PDBx:U33>0.24794</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2500">
         <PDBx:U11>0.91268</PDBx:U11>
         <PDBx:U12>-0.18677</PDBx:U12>
         <PDBx:U13>0.08763</PDBx:U13>
         <PDBx:U22>0.31326</PDBx:U22>
         <PDBx:U23>-0.01922</PDBx:U23>
         <PDBx:U33>0.25746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2501">
         <PDBx:U11>0.91035</PDBx:U11>
         <PDBx:U12>-0.19366</PDBx:U12>
         <PDBx:U13>0.10041</PDBx:U13>
         <PDBx:U22>0.32133</PDBx:U22>
         <PDBx:U23>-0.02146</PDBx:U23>
         <PDBx:U33>0.26407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2502">
         <PDBx:U11>0.86258</PDBx:U11>
         <PDBx:U12>-0.18181</PDBx:U12>
         <PDBx:U13>0.09291</PDBx:U13>
         <PDBx:U22>0.30069</PDBx:U22>
         <PDBx:U23>-0.01957</PDBx:U23>
         <PDBx:U33>0.24936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2503">
         <PDBx:U11>0.89419</PDBx:U11>
         <PDBx:U12>-0.18383</PDBx:U12>
         <PDBx:U13>0.10777</PDBx:U13>
         <PDBx:U22>0.35816</PDBx:U22>
         <PDBx:U23>-0.02218</PDBx:U23>
         <PDBx:U33>0.30751</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2504">
         <PDBx:U11>0.96129</PDBx:U11>
         <PDBx:U12>-0.20476</PDBx:U12>
         <PDBx:U13>0.09401</PDBx:U13>
         <PDBx:U22>0.33812</PDBx:U22>
         <PDBx:U23>-0.01814</PDBx:U23>
         <PDBx:U33>0.27552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2505">
         <PDBx:U11>1.01600</PDBx:U11>
         <PDBx:U12>-0.21706</PDBx:U12>
         <PDBx:U13>0.09857</PDBx:U13>
         <PDBx:U22>0.36063</PDBx:U22>
         <PDBx:U23>-0.01867</PDBx:U23>
         <PDBx:U33>0.29087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2506">
         <PDBx:U11>1.06557</PDBx:U11>
         <PDBx:U12>-0.22837</PDBx:U12>
         <PDBx:U13>0.09399</PDBx:U13>
         <PDBx:U22>0.37885</PDBx:U22>
         <PDBx:U23>-0.01500</PDBx:U23>
         <PDBx:U33>0.30376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2507">
         <PDBx:U11>1.07819</PDBx:U11>
         <PDBx:U12>-0.22069</PDBx:U12>
         <PDBx:U13>0.06624</PDBx:U13>
         <PDBx:U22>0.36849</PDBx:U22>
         <PDBx:U23>-0.00816</PDBx:U23>
         <PDBx:U33>0.29734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2508">
         <PDBx:U11>1.11362</PDBx:U11>
         <PDBx:U12>-0.22018</PDBx:U12>
         <PDBx:U13>0.05012</PDBx:U13>
         <PDBx:U22>0.37347</PDBx:U22>
         <PDBx:U23>-0.00419</PDBx:U23>
         <PDBx:U33>0.30160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2509">
         <PDBx:U11>1.13927</PDBx:U11>
         <PDBx:U12>-0.22749</PDBx:U12>
         <PDBx:U13>0.05904</PDBx:U13>
         <PDBx:U22>0.38781</PDBx:U22>
         <PDBx:U23>-0.00617</PDBx:U23>
         <PDBx:U33>0.30980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2510">
         <PDBx:U11>1.12491</PDBx:U11>
         <PDBx:U12>-0.21199</PDBx:U12>
         <PDBx:U13>0.02510</PDBx:U13>
         <PDBx:U22>0.36622</PDBx:U22>
         <PDBx:U23>0.00171</PDBx:U23>
         <PDBx:U33>0.29987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>282</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2511">
         <PDBx:U11>0.84888</PDBx:U11>
         <PDBx:U12>-0.16932</PDBx:U12>
         <PDBx:U13>0.06960</PDBx:U13>
         <PDBx:U22>0.28183</PDBx:U22>
         <PDBx:U23>-0.01459</PDBx:U23>
         <PDBx:U33>0.23542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2512">
         <PDBx:U11>0.80569</PDBx:U11>
         <PDBx:U12>-0.15745</PDBx:U12>
         <PDBx:U13>0.06199</PDBx:U13>
         <PDBx:U22>0.26309</PDBx:U22>
         <PDBx:U23>-0.01285</PDBx:U23>
         <PDBx:U33>0.22181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2513">
         <PDBx:U11>0.89358</PDBx:U11>
         <PDBx:U12>-0.15079</PDBx:U12>
         <PDBx:U13>0.07559</PDBx:U13>
         <PDBx:U22>0.38743</PDBx:U22>
         <PDBx:U23>-0.01621</PDBx:U23>
         <PDBx:U33>0.34854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2514">
         <PDBx:U11>0.77642</PDBx:U11>
         <PDBx:U12>-0.14915</PDBx:U12>
         <PDBx:U13>0.08482</PDBx:U13>
         <PDBx:U22>0.29670</PDBx:U22>
         <PDBx:U23>-0.01737</PDBx:U23>
         <PDBx:U33>0.25908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2515">
         <PDBx:U11>0.81131</PDBx:U11>
         <PDBx:U12>-0.14411</PDBx:U12>
         <PDBx:U13>0.03466</PDBx:U13>
         <PDBx:U22>0.25648</PDBx:U22>
         <PDBx:U23>-0.00742</PDBx:U23>
         <PDBx:U33>0.22154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2516">
         <PDBx:U11>0.85417</PDBx:U11>
         <PDBx:U12>-0.13159</PDBx:U12>
         <PDBx:U13>0.02764</PDBx:U13>
         <PDBx:U22>0.32429</PDBx:U22>
         <PDBx:U23>-0.00614</PDBx:U23>
         <PDBx:U33>0.29425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2517">
         <PDBx:U11>0.91430</PDBx:U11>
         <PDBx:U12>-0.13468</PDBx:U12>
         <PDBx:U13>0.02906</PDBx:U13>
         <PDBx:U22>0.38839</PDBx:U22>
         <PDBx:U23>-0.00576</PDBx:U23>
         <PDBx:U33>0.35648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2518">
         <PDBx:U11>0.84664</PDBx:U11>
         <PDBx:U12>-0.11726</PDBx:U12>
         <PDBx:U13>0.02075</PDBx:U13>
         <PDBx:U22>0.33817</PDBx:U22>
         <PDBx:U23>-0.00455</PDBx:U23>
         <PDBx:U33>0.31322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2519">
         <PDBx:U11>0.99139</PDBx:U11>
         <PDBx:U12>-0.12377</PDBx:U12>
         <PDBx:U13>0.02276</PDBx:U13>
         <PDBx:U22>0.48752</PDBx:U22>
         <PDBx:U23>-0.00422</PDBx:U23>
         <PDBx:U33>0.45924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2520">
         <PDBx:U11>0.87092</PDBx:U11>
         <PDBx:U12>-0.10573</PDBx:U12>
         <PDBx:U13>0.01490</PDBx:U13>
         <PDBx:U22>0.38568</PDBx:U22>
         <PDBx:U23>-0.00315</PDBx:U23>
         <PDBx:U33>0.36418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2521">
         <PDBx:U11>0.90397</PDBx:U11>
         <PDBx:U12>-0.10928</PDBx:U12>
         <PDBx:U13>0.01570</PDBx:U13>
         <PDBx:U22>0.41930</PDBx:U22>
         <PDBx:U23>-0.00343</PDBx:U23>
         <PDBx:U33>0.39634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2522">
         <PDBx:U11>0.88055</PDBx:U11>
         <PDBx:U12>-0.09890</PDBx:U12>
         <PDBx:U13>0.00976</PDBx:U13>
         <PDBx:U22>0.41599</PDBx:U22>
         <PDBx:U23>-0.00202</PDBx:U23>
         <PDBx:U33>0.39603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>283</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2523">
         <PDBx:U11>0.81357</PDBx:U11>
         <PDBx:U12>-0.14693</PDBx:U12>
         <PDBx:U13>0.07679</PDBx:U13>
         <PDBx:U22>0.30984</PDBx:U22>
         <PDBx:U23>-0.01719</PDBx:U23>
         <PDBx:U33>0.27163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2524">
         <PDBx:U11>0.83704</PDBx:U11>
         <PDBx:U12>-0.13988</PDBx:U12>
         <PDBx:U13>0.08933</PDBx:U13>
         <PDBx:U22>0.36693</PDBx:U22>
         <PDBx:U23>-0.02056</PDBx:U23>
         <PDBx:U33>0.33106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2525">
         <PDBx:U11>0.70986</PDBx:U11>
         <PDBx:U12>-0.14863</PDBx:U12>
         <PDBx:U13>0.11521</PDBx:U13>
         <PDBx:U22>0.25852</PDBx:U22>
         <PDBx:U23>-0.02690</PDBx:U23>
         <PDBx:U33>0.22258</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2526">
         <PDBx:U11>0.82039</PDBx:U11>
         <PDBx:U12>-0.14268</PDBx:U12>
         <PDBx:U13>0.12422</PDBx:U13>
         <PDBx:U22>0.40106</PDBx:U22>
         <PDBx:U23>-0.02852</PDBx:U23>
         <PDBx:U33>0.36922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2527">
         <PDBx:U11>0.76165</PDBx:U11>
         <PDBx:U12>-0.13598</PDBx:U12>
         <PDBx:U13>0.08691</PDBx:U13>
         <PDBx:U22>0.28874</PDBx:U22>
         <PDBx:U23>-0.02075</PDBx:U23>
         <PDBx:U33>0.25185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2528">
         <PDBx:U11>0.71887</PDBx:U11>
         <PDBx:U12>-0.13135</PDBx:U12>
         <PDBx:U13>0.10416</PDBx:U13>
         <PDBx:U22>0.27731</PDBx:U22>
         <PDBx:U23>-0.02618</PDBx:U23>
         <PDBx:U33>0.24295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2529">
         <PDBx:U11>0.74306</PDBx:U11>
         <PDBx:U12>-0.12327</PDBx:U12>
         <PDBx:U13>0.06141</PDBx:U13>
         <PDBx:U22>0.26641</PDBx:U22>
         <PDBx:U23>-0.01405</PDBx:U23>
         <PDBx:U33>0.23036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>284</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2530">
         <PDBx:U11>0.74893</PDBx:U11>
         <PDBx:U12>-0.16222</PDBx:U12>
         <PDBx:U13>0.12740</PDBx:U13>
         <PDBx:U22>0.27962</PDBx:U22>
         <PDBx:U23>-0.03016</PDBx:U23>
         <PDBx:U33>0.23976</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2531">
         <PDBx:U11>0.88254</PDBx:U11>
         <PDBx:U12>-0.17017</PDBx:U12>
         <PDBx:U13>0.15194</PDBx:U13>
         <PDBx:U22>0.43257</PDBx:U22>
         <PDBx:U23>-0.03590</PDBx:U23>
         <PDBx:U33>0.39399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2532">
         <PDBx:U11>0.95376</PDBx:U11>
         <PDBx:U12>-0.17119</PDBx:U12>
         <PDBx:U13>0.15375</PDBx:U13>
         <PDBx:U22>0.52270</PDBx:U22>
         <PDBx:U23>-0.03361</PDBx:U23>
         <PDBx:U33>0.48614</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2533">
         <PDBx:U11>0.93335</PDBx:U11>
         <PDBx:U12>-0.17081</PDBx:U12>
         <PDBx:U13>0.16973</PDBx:U13>
         <PDBx:U22>0.53407</PDBx:U22>
         <PDBx:U23>-0.03664</PDBx:U23>
         <PDBx:U33>0.50322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2534">
         <PDBx:U11>0.93837</PDBx:U11>
         <PDBx:U12>-0.18511</PDBx:U12>
         <PDBx:U13>0.16296</PDBx:U13>
         <PDBx:U22>0.46223</PDBx:U22>
         <PDBx:U23>-0.03894</PDBx:U23>
         <PDBx:U33>0.41773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2535">
         <PDBx:U11>1.02328</PDBx:U11>
         <PDBx:U12>-0.18514</PDBx:U12>
         <PDBx:U13>0.16405</PDBx:U13>
         <PDBx:U22>0.53290</PDBx:U22>
         <PDBx:U23>-0.04131</PDBx:U23>
         <PDBx:U33>0.48711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>285</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2536">
         <PDBx:U11>0.91387</PDBx:U11>
         <PDBx:U12>-0.17227</PDBx:U12>
         <PDBx:U13>0.13668</PDBx:U13>
         <PDBx:U22>0.46396</PDBx:U22>
         <PDBx:U23>-0.02793</PDBx:U23>
         <PDBx:U33>0.42435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2537">
         <PDBx:U11>0.97212</PDBx:U11>
         <PDBx:U12>-0.17451</PDBx:U12>
         <PDBx:U13>0.13697</PDBx:U13>
         <PDBx:U22>0.53726</PDBx:U22>
         <PDBx:U23>-0.02490</PDBx:U23>
         <PDBx:U33>0.50030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2538">
         <PDBx:U11>0.87748</PDBx:U11>
         <PDBx:U12>-0.16103</PDBx:U12>
         <PDBx:U13>0.12943</PDBx:U13>
         <PDBx:U22>0.47033</PDBx:U22>
         <PDBx:U23>-0.02234</PDBx:U23>
         <PDBx:U33>0.43966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2539">
         <PDBx:U11>0.90094</PDBx:U11>
         <PDBx:U12>-0.16154</PDBx:U12>
         <PDBx:U13>0.14005</PDBx:U13>
         <PDBx:U22>0.52423</PDBx:U22>
         <PDBx:U23>-0.02283</PDBx:U23>
         <PDBx:U33>0.49992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2540">
         <PDBx:U11>1.01356</PDBx:U11>
         <PDBx:U12>-0.18026</PDBx:U12>
         <PDBx:U13>0.12112</PDBx:U13>
         <PDBx:U22>0.54609</PDBx:U22>
         <PDBx:U23>-0.01981</PDBx:U23>
         <PDBx:U33>0.50481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2541">
         <PDBx:U11>1.18671</PDBx:U11>
         <PDBx:U12>-0.18880</PDBx:U12>
         <PDBx:U13>0.12532</PDBx:U13>
         <PDBx:U22>0.72718</PDBx:U22>
         <PDBx:U23>-0.01714</PDBx:U23>
         <PDBx:U33>0.68871</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2542">
         <PDBx:U11>1.31558</PDBx:U11>
         <PDBx:U12>-0.18916</PDBx:U12>
         <PDBx:U13>0.10440</PDBx:U13>
         <PDBx:U22>0.82510</PDBx:U22>
         <PDBx:U23>-0.01120</PDBx:U23>
         <PDBx:U33>0.78493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2543">
         <PDBx:U11>1.35249</PDBx:U11>
         <PDBx:U12>-0.17294</PDBx:U12>
         <PDBx:U13>0.08207</PDBx:U13>
         <PDBx:U22>0.85706</PDBx:U22>
         <PDBx:U23>-0.00828</PDBx:U23>
         <PDBx:U33>0.81885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2544">
         <PDBx:U11>1.33495</PDBx:U11>
         <PDBx:U12>-0.16266</PDBx:U12>
         <PDBx:U13>0.07308</PDBx:U13>
         <PDBx:U22>0.85845</PDBx:U22>
         <PDBx:U23>-0.00565</PDBx:U23>
         <PDBx:U33>0.82689</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2545">
         <PDBx:U11>1.35147</PDBx:U11>
         <PDBx:U12>-0.16779</PDBx:U12>
         <PDBx:U13>0.08336</PDBx:U13>
         <PDBx:U22>0.89911</PDBx:U22>
         <PDBx:U23>-0.00540</PDBx:U23>
         <PDBx:U33>0.87436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2546">
         <PDBx:U11>1.29969</PDBx:U11>
         <PDBx:U12>-0.14745</PDBx:U12>
         <PDBx:U13>0.05327</PDBx:U13>
         <PDBx:U22>0.81816</PDBx:U22>
         <PDBx:U23>-0.00355</PDBx:U23>
         <PDBx:U33>0.78806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>286</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2547">
         <PDBx:U11>0.82936</PDBx:U11>
         <PDBx:U12>-0.14903</PDBx:U12>
         <PDBx:U13>0.11088</PDBx:U13>
         <PDBx:U22>0.41263</PDBx:U22>
         <PDBx:U23>-0.01950</PDBx:U23>
         <PDBx:U33>0.38124</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2548">
         <PDBx:U11>0.82190</PDBx:U11>
         <PDBx:U12>-0.13615</PDBx:U12>
         <PDBx:U13>0.10011</PDBx:U13>
         <PDBx:U22>0.42451</PDBx:U22>
         <PDBx:U23>-0.01585</PDBx:U23>
         <PDBx:U33>0.39770</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2549">
         <PDBx:U11>0.85197</PDBx:U11>
         <PDBx:U12>-0.12846</PDBx:U12>
         <PDBx:U13>0.11295</PDBx:U13>
         <PDBx:U22>0.48889</PDBx:U22>
         <PDBx:U23>-0.01876</PDBx:U23>
         <PDBx:U33>0.46613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2550">
         <PDBx:U11>0.75189</PDBx:U11>
         <PDBx:U12>-0.12088</PDBx:U12>
         <PDBx:U13>0.11026</PDBx:U13>
         <PDBx:U22>0.41115</PDBx:U22>
         <PDBx:U23>-0.01594</PDBx:U23>
         <PDBx:U33>0.39317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>287</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2551">
         <PDBx:U11>0.79707</PDBx:U11>
         <PDBx:U12>-0.12508</PDBx:U12>
         <PDBx:U13>0.07528</PDBx:U13>
         <PDBx:U22>0.37807</PDBx:U22>
         <PDBx:U23>-0.01214</PDBx:U23>
         <PDBx:U33>0.34973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>291</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>292</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.47704</PDBx:U11>
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         <PDBx:U13>0.14975</PDBx:U13>
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         <PDBx:U23>-0.02411</PDBx:U23>
         <PDBx:U33>0.43225</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.41254</PDBx:U11>
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         <PDBx:U13>0.14054</PDBx:U13>
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         <PDBx:U23>-0.02209</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01981</PDBx:U23>
         <PDBx:U33>0.32987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.35204</PDBx:U11>
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         <PDBx:U23>-0.02234</PDBx:U23>
         <PDBx:U33>0.28107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.44636</PDBx:U11>
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         <PDBx:U23>-0.02298</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02093</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02557</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.63807</PDBx:U11>
         <PDBx:U12>-0.09751</PDBx:U12>
         <PDBx:U13>0.12401</PDBx:U13>
         <PDBx:U22>0.42839</PDBx:U22>
         <PDBx:U23>-0.02036</PDBx:U23>
         <PDBx:U33>0.43861</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.54147</PDBx:U11>
         <PDBx:U12>-0.08634</PDBx:U12>
         <PDBx:U13>0.14211</PDBx:U13>
         <PDBx:U22>0.34481</PDBx:U22>
         <PDBx:U23>-0.02579</PDBx:U23>
         <PDBx:U33>0.35628</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02268</PDBx:U23>
         <PDBx:U33>0.38540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>294</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.07049</PDBx:U12>
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         <PDBx:U23>-0.02304</PDBx:U23>
         <PDBx:U33>0.38726</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>-0.06245</PDBx:U12>
         <PDBx:U13>0.14114</PDBx:U13>
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         <PDBx:U23>-0.02031</PDBx:U23>
         <PDBx:U33>0.44473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.02344</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U12>-0.05423</PDBx:U12>
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         <PDBx:U23>-0.02093</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>295</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>296</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>297</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2633">
         <PDBx:U11>0.26470</PDBx:U11>
         <PDBx:U12>-0.05334</PDBx:U12>
         <PDBx:U13>0.13946</PDBx:U13>
         <PDBx:U22>0.46881</PDBx:U22>
         <PDBx:U23>-0.01546</PDBx:U23>
         <PDBx:U33>0.56687</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2634">
         <PDBx:U11>0.29528</PDBx:U11>
         <PDBx:U12>-0.03739</PDBx:U12>
         <PDBx:U13>0.14350</PDBx:U13>
         <PDBx:U22>0.50706</PDBx:U22>
         <PDBx:U23>-0.01359</PDBx:U23>
         <PDBx:U33>0.60975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2635">
         <PDBx:U11>0.29133</PDBx:U11>
         <PDBx:U12>-0.02053</PDBx:U12>
         <PDBx:U13>0.12613</PDBx:U13>
         <PDBx:U22>0.52850</PDBx:U22>
         <PDBx:U23>-0.00738</PDBx:U23>
         <PDBx:U33>0.63091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2636">
         <PDBx:U11>0.30452</PDBx:U11>
         <PDBx:U12>-0.00813</PDBx:U12>
         <PDBx:U13>0.12790</PDBx:U13>
         <PDBx:U22>0.54838</PDBx:U22>
         <PDBx:U23>-0.00594</PDBx:U23>
         <PDBx:U33>0.65533</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2637">
         <PDBx:U11>0.39976</PDBx:U11>
         <PDBx:U12>-0.04407</PDBx:U12>
         <PDBx:U13>0.15730</PDBx:U13>
         <PDBx:U22>0.62297</PDBx:U22>
         <PDBx:U23>-0.01704</PDBx:U23>
         <PDBx:U33>0.73112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2638">
         <PDBx:U11>0.48870</PDBx:U11>
         <PDBx:U12>-0.05792</PDBx:U12>
         <PDBx:U13>0.17578</PDBx:U13>
         <PDBx:U22>0.68224</PDBx:U22>
         <PDBx:U23>-0.02272</PDBx:U23>
         <PDBx:U33>0.78930</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2639">
         <PDBx:U11>0.57952</PDBx:U11>
         <PDBx:U12>-0.05079</PDBx:U12>
         <PDBx:U13>0.18174</PDBx:U13>
         <PDBx:U22>0.74016</PDBx:U22>
         <PDBx:U23>-0.02419</PDBx:U23>
         <PDBx:U33>0.84584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2640">
         <PDBx:U11>0.59682</PDBx:U11>
         <PDBx:U12>-0.06081</PDBx:U12>
         <PDBx:U13>0.18684</PDBx:U13>
         <PDBx:U22>0.72663</PDBx:U22>
         <PDBx:U23>-0.02657</PDBx:U23>
         <PDBx:U33>0.82579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2641">
         <PDBx:U11>0.59868</PDBx:U11>
         <PDBx:U12>-0.03426</PDBx:U12>
         <PDBx:U13>0.18012</PDBx:U13>
         <PDBx:U22>0.76418</PDBx:U22>
         <PDBx:U23>-0.02268</PDBx:U23>
         <PDBx:U33>0.87572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>298</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2642">
         <PDBx:U11>0.30708</PDBx:U11>
         <PDBx:U12>-0.02039</PDBx:U12>
         <PDBx:U13>0.10900</PDBx:U13>
         <PDBx:U22>0.55631</PDBx:U22>
         <PDBx:U23>-0.00406</PDBx:U23>
         <PDBx:U33>0.65333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2643">
         <PDBx:U11>0.30713</PDBx:U11>
         <PDBx:U12>-0.02050</PDBx:U12>
         <PDBx:U13>0.10905</PDBx:U13>
         <PDBx:U22>0.55621</PDBx:U22>
         <PDBx:U23>-0.00409</PDBx:U23>
         <PDBx:U33>0.65322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2644">
         <PDBx:U11>0.31536</PDBx:U11>
         <PDBx:U12>-0.00491</PDBx:U12>
         <PDBx:U13>0.09060</PDBx:U13>
         <PDBx:U22>0.58464</PDBx:U22>
         <PDBx:U23>0.00241</PDBx:U23>
         <PDBx:U33>0.67732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2645">
         <PDBx:U11>0.31798</PDBx:U11>
         <PDBx:U12>-0.00487</PDBx:U12>
         <PDBx:U13>0.09066</PDBx:U13>
         <PDBx:U22>0.58639</PDBx:U22>
         <PDBx:U23>0.00241</PDBx:U23>
         <PDBx:U33>0.67900</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2646">
         <PDBx:U11>0.30250</PDBx:U11>
         <PDBx:U12>0.01105</PDBx:U12>
         <PDBx:U13>0.09007</PDBx:U13>
         <PDBx:U22>0.55340</PDBx:U22>
         <PDBx:U23>0.00570</PDBx:U23>
         <PDBx:U33>0.64523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2647">
         <PDBx:U11>0.30400</PDBx:U11>
         <PDBx:U12>0.01108</PDBx:U12>
         <PDBx:U13>0.09112</PDBx:U13>
         <PDBx:U22>0.55474</PDBx:U22>
         <PDBx:U23>0.00547</PDBx:U23>
         <PDBx:U33>0.64716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2648">
         <PDBx:U11>0.27179</PDBx:U11>
         <PDBx:U12>0.01011</PDBx:U12>
         <PDBx:U13>0.09824</PDBx:U13>
         <PDBx:U22>0.49572</PDBx:U22>
         <PDBx:U23>0.00392</PDBx:U23>
         <PDBx:U33>0.58782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2649">
         <PDBx:U11>0.28506</PDBx:U11>
         <PDBx:U12>0.01004</PDBx:U12>
         <PDBx:U13>0.10094</PDBx:U13>
         <PDBx:U22>0.50856</PDBx:U22>
         <PDBx:U23>0.00327</PDBx:U23>
         <PDBx:U33>0.60216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2650">
         <PDBx:U11>0.33539</PDBx:U11>
         <PDBx:U12>-0.00903</PDBx:U12>
         <PDBx:U13>0.07192</PDBx:U13>
         <PDBx:U22>0.61470</PDBx:U22>
         <PDBx:U23>0.00472</PDBx:U23>
         <PDBx:U33>0.70019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2651">
         <PDBx:U11>0.33618</PDBx:U11>
         <PDBx:U12>-0.00757</PDBx:U12>
         <PDBx:U13>0.07202</PDBx:U13>
         <PDBx:U22>0.61190</PDBx:U22>
         <PDBx:U23>0.00506</PDBx:U23>
         <PDBx:U33>0.69703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2652">
         <PDBx:U11>0.36105</PDBx:U11>
         <PDBx:U12>0.00618</PDBx:U12>
         <PDBx:U13>0.05151</PDBx:U13>
         <PDBx:U22>0.65700</PDBx:U22>
         <PDBx:U23>0.01167</PDBx:U23>
         <PDBx:U33>0.73325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2653">
         <PDBx:U11>0.36199</PDBx:U11>
         <PDBx:U12>-0.02351</PDBx:U12>
         <PDBx:U13>0.06609</PDBx:U13>
         <PDBx:U22>0.65713</PDBx:U22>
         <PDBx:U23>0.00186</PDBx:U23>
         <PDBx:U33>0.74211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2654">
         <PDBx:U11>0.33122</PDBx:U11>
         <PDBx:U12>0.01836</PDBx:U12>
         <PDBx:U13>0.04623</PDBx:U13>
         <PDBx:U22>0.61240</PDBx:U22>
         <PDBx:U23>0.01581</PDBx:U23>
         <PDBx:U33>0.68308</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2655">
         <PDBx:U11>0.34994</PDBx:U11>
         <PDBx:U12>-0.02679</PDBx:U12>
         <PDBx:U13>0.07106</PDBx:U13>
         <PDBx:U22>0.66581</PDBx:U22>
         <PDBx:U23>0.00081</PDBx:U23>
         <PDBx:U33>0.75460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2656">
         <PDBx:U11>0.34514</PDBx:U11>
         <PDBx:U12>0.00508</PDBx:U12>
         <PDBx:U13>0.04082</PDBx:U13>
         <PDBx:U22>0.66760</PDBx:U22>
         <PDBx:U23>0.01258</PDBx:U23>
         <PDBx:U33>0.74082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2657">
         <PDBx:U11>0.41417</PDBx:U11>
         <PDBx:U12>-0.03198</PDBx:U12>
         <PDBx:U13>0.05259</PDBx:U13>
         <PDBx:U22>0.69283</PDBx:U22>
         <PDBx:U23>0.00012</PDBx:U23>
         <PDBx:U33>0.76371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>299</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2658">
         <PDBx:U11>0.23149</PDBx:U11>
         <PDBx:U12>0.02465</PDBx:U12>
         <PDBx:U13>0.08000</PDBx:U13>
         <PDBx:U22>0.49587</PDBx:U22>
         <PDBx:U23>0.01013</PDBx:U23>
         <PDBx:U33>0.58672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2659">
         <PDBx:U11>0.26724</PDBx:U11>
         <PDBx:U12>0.03747</PDBx:U12>
         <PDBx:U13>0.08109</PDBx:U13>
         <PDBx:U22>0.51378</PDBx:U22>
         <PDBx:U23>0.01243</PDBx:U23>
         <PDBx:U33>0.60717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2660">
         <PDBx:U11>0.23334</PDBx:U11>
         <PDBx:U12>0.04108</PDBx:U12>
         <PDBx:U13>0.07400</PDBx:U13>
         <PDBx:U22>0.45966</PDBx:U22>
         <PDBx:U23>0.01534</PDBx:U23>
         <PDBx:U33>0.54475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2661">
         <PDBx:U11>0.21314</PDBx:U11>
         <PDBx:U12>0.04548</PDBx:U12>
         <PDBx:U13>0.08017</PDBx:U13>
         <PDBx:U22>0.41678</PDBx:U22>
         <PDBx:U23>0.01502</PDBx:U23>
         <PDBx:U33>0.50483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2662">
         <PDBx:U11>0.34974</PDBx:U11>
         <PDBx:U12>0.04958</PDBx:U12>
         <PDBx:U13>0.07114</PDBx:U13>
         <PDBx:U22>0.61344</PDBx:U22>
         <PDBx:U23>0.01648</PDBx:U23>
         <PDBx:U33>0.70886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2663">
         <PDBx:U11>0.43093</PDBx:U11>
         <PDBx:U12>0.05216</PDBx:U12>
         <PDBx:U13>0.05084</PDBx:U13>
         <PDBx:U22>0.71232</PDBx:U22>
         <PDBx:U23>0.02105</PDBx:U23>
         <PDBx:U33>0.79589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2664">
         <PDBx:U11>0.26540</PDBx:U11>
         <PDBx:U12>0.06040</PDBx:U12>
         <PDBx:U13>0.07295</PDBx:U13>
         <PDBx:U22>0.50822</PDBx:U22>
         <PDBx:U23>0.01879</PDBx:U23>
         <PDBx:U33>0.60918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>300</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2665">
         <PDBx:U11>0.20487</PDBx:U11>
         <PDBx:U12>0.03925</PDBx:U12>
         <PDBx:U13>0.06060</PDBx:U13>
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         <PDBx:U33>0.67114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>303</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2698">
         <PDBx:U11>0.62181</PDBx:U11>
         <PDBx:U12>0.01593</PDBx:U12>
         <PDBx:U13>0.13548</PDBx:U13>
         <PDBx:U22>0.79850</PDBx:U22>
         <PDBx:U23>-0.00503</PDBx:U23>
         <PDBx:U33>0.90946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>303</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2699">
         <PDBx:U11>0.86544</PDBx:U11>
         <PDBx:U12>0.01012</PDBx:U12>
         <PDBx:U13>0.15402</PDBx:U13>
         <PDBx:U22>1.02173</PDBx:U22>
         <PDBx:U23>-0.01158</PDBx:U23>
         <PDBx:U33>1.13935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>303</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2700">
         <PDBx:U11>0.92346</PDBx:U11>
         <PDBx:U12>0.01637</PDBx:U12>
         <PDBx:U13>0.15720</PDBx:U13>
         <PDBx:U22>1.05963</PDBx:U22>
         <PDBx:U23>-0.01235</PDBx:U23>
         <PDBx:U33>1.18143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>303</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2701">
         <PDBx:U11>0.94995</PDBx:U11>
         <PDBx:U12>-0.00150</PDBx:U12>
         <PDBx:U13>0.16519</PDBx:U13>
         <PDBx:U22>1.10978</PDBx:U22>
         <PDBx:U23>-0.01608</PDBx:U23>
         <PDBx:U33>1.22822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>303</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2702">
         <PDBx:U11>0.20956</PDBx:U11>
         <PDBx:U12>0.04450</PDBx:U12>
         <PDBx:U13>0.09591</PDBx:U13>
         <PDBx:U22>0.35976</PDBx:U22>
         <PDBx:U23>0.01094</PDBx:U23>
         <PDBx:U33>0.45062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2703">
         <PDBx:U11>0.25385</PDBx:U11>
         <PDBx:U12>0.05328</PDBx:U12>
         <PDBx:U13>0.08766</PDBx:U13>
         <PDBx:U22>0.39246</PDBx:U22>
         <PDBx:U23>0.01517</PDBx:U23>
         <PDBx:U33>0.48013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2704">
         <PDBx:U11>0.19820</PDBx:U11>
         <PDBx:U12>0.05085</PDBx:U12>
         <PDBx:U13>0.08837</PDBx:U13>
         <PDBx:U22>0.31663</PDBx:U22>
         <PDBx:U23>0.01403</PDBx:U23>
         <PDBx:U33>0.39728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2705">
         <PDBx:U11>0.17417</PDBx:U11>
         <PDBx:U12>0.05304</PDBx:U12>
         <PDBx:U13>0.09099</PDBx:U13>
         <PDBx:U22>0.27400</PDBx:U22>
         <PDBx:U23>0.01358</PDBx:U23>
         <PDBx:U33>0.35706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2706">
         <PDBx:U11>0.23332</PDBx:U11>
         <PDBx:U12>0.06066</PDBx:U12>
         <PDBx:U13>0.07100</PDBx:U13>
         <PDBx:U22>0.38957</PDBx:U22>
         <PDBx:U23>0.02150</PDBx:U23>
         <PDBx:U33>0.46944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2707">
         <PDBx:U11>0.16451</PDBx:U11>
         <PDBx:U12>0.06637</PDBx:U12>
         <PDBx:U13>0.06927</PDBx:U13>
         <PDBx:U22>0.33528</PDBx:U22>
         <PDBx:U23>0.02349</PDBx:U23>
         <PDBx:U33>0.42352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2708">
         <PDBx:U11>0.25697</PDBx:U11>
         <PDBx:U12>0.07190</PDBx:U12>
         <PDBx:U13>0.05251</PDBx:U13>
         <PDBx:U22>0.44439</PDBx:U22>
         <PDBx:U23>0.02906</PDBx:U23>
         <PDBx:U33>0.52342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2709">
         <PDBx:U11>0.34349</PDBx:U11>
         <PDBx:U12>0.07881</PDBx:U12>
         <PDBx:U13>0.04967</PDBx:U13>
         <PDBx:U22>0.54363</PDBx:U22>
         <PDBx:U23>0.03171</PDBx:U23>
         <PDBx:U33>0.63109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2710">
         <PDBx:U11>0.38783</PDBx:U11>
         <PDBx:U12>0.08250</PDBx:U12>
         <PDBx:U13>0.03659</PDBx:U13>
         <PDBx:U22>0.60735</PDBx:U22>
         <PDBx:U23>0.03529</PDBx:U23>
         <PDBx:U33>0.68921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2711">
         <PDBx:U11>0.37812</PDBx:U11>
         <PDBx:U12>0.07917</PDBx:U12>
         <PDBx:U13>0.02545</PDBx:U13>
         <PDBx:U22>0.60593</PDBx:U22>
         <PDBx:U23>0.03622</PDBx:U23>
         <PDBx:U33>0.67374</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2712">
         <PDBx:U11>0.42095</PDBx:U11>
         <PDBx:U12>0.08972</PDBx:U12>
         <PDBx:U13>0.03417</PDBx:U13>
         <PDBx:U22>0.65124</PDBx:U22>
         <PDBx:U23>0.03791</PDBx:U23>
         <PDBx:U33>0.74188</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>304</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2713">
         <PDBx:U11>0.18771</PDBx:U11>
         <PDBx:U12>0.04621</PDBx:U12>
         <PDBx:U13>0.08622</PDBx:U13>
         <PDBx:U22>0.30987</PDBx:U22>
         <PDBx:U23>0.01347</PDBx:U23>
         <PDBx:U33>0.38291</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2714">
         <PDBx:U11>0.18273</PDBx:U11>
         <PDBx:U12>0.04362</PDBx:U12>
         <PDBx:U13>0.08473</PDBx:U13>
         <PDBx:U22>0.28251</PDBx:U22>
         <PDBx:U23>0.01138</PDBx:U23>
         <PDBx:U33>0.34649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2715">
         <PDBx:U11>0.18010</PDBx:U11>
         <PDBx:U12>0.03689</PDBx:U12>
         <PDBx:U13>0.09971</PDBx:U13>
         <PDBx:U22>0.25523</PDBx:U22>
         <PDBx:U23>0.00508</PDBx:U23>
         <PDBx:U33>0.32570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2716">
         <PDBx:U11>0.19375</PDBx:U11>
         <PDBx:U12>0.03935</PDBx:U12>
         <PDBx:U13>0.09922</PDBx:U13>
         <PDBx:U22>0.25025</PDBx:U22>
         <PDBx:U23>0.00443</PDBx:U23>
         <PDBx:U33>0.31854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2717">
         <PDBx:U11>0.15735</PDBx:U11>
         <PDBx:U12>0.03472</PDBx:U12>
         <PDBx:U13>0.07361</PDBx:U13>
         <PDBx:U22>0.25349</PDBx:U22>
         <PDBx:U23>0.00890</PDBx:U23>
         <PDBx:U33>0.30316</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2718">
         <PDBx:U11>0.21523</PDBx:U11>
         <PDBx:U12>0.02964</PDBx:U12>
         <PDBx:U13>0.06955</PDBx:U13>
         <PDBx:U22>0.28161</PDBx:U22>
         <PDBx:U23>0.00496</PDBx:U23>
         <PDBx:U33>0.32105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2719">
         <PDBx:U11>0.21253</PDBx:U11>
         <PDBx:U12>0.04001</PDBx:U12>
         <PDBx:U13>0.06152</PDBx:U13>
         <PDBx:U22>0.27425</PDBx:U22>
         <PDBx:U23>0.00823</PDBx:U23>
         <PDBx:U33>0.30757</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2720">
         <PDBx:U11>0.24628</PDBx:U11>
         <PDBx:U12>0.02151</PDBx:U12>
         <PDBx:U13>0.05861</PDBx:U13>
         <PDBx:U22>0.30681</PDBx:U22>
         <PDBx:U23>0.00248</PDBx:U23>
         <PDBx:U33>0.33536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>305</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2721">
         <PDBx:U11>0.22919</PDBx:U11>
         <PDBx:U12>0.02780</PDBx:U12>
         <PDBx:U13>0.11351</PDBx:U13>
         <PDBx:U22>0.30449</PDBx:U22>
         <PDBx:U23>0.00018</PDBx:U23>
         <PDBx:U33>0.38251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2722">
         <PDBx:U11>0.22332</PDBx:U11>
         <PDBx:U12>0.01961</PDBx:U12>
         <PDBx:U13>0.12741</PDBx:U13>
         <PDBx:U22>0.27207</PDBx:U22>
         <PDBx:U23>-0.00630</PDBx:U23>
         <PDBx:U33>0.35231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2723">
         <PDBx:U11>0.18668</PDBx:U11>
         <PDBx:U12>0.02560</PDBx:U12>
         <PDBx:U13>0.13178</PDBx:U13>
         <PDBx:U22>0.22735</PDBx:U22>
         <PDBx:U23>-0.00674</PDBx:U23>
         <PDBx:U33>0.31709</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2724">
         <PDBx:U11>0.25739</PDBx:U11>
         <PDBx:U12>0.02148</PDBx:U12>
         <PDBx:U13>0.13861</PDBx:U13>
         <PDBx:U22>0.27334</PDBx:U22>
         <PDBx:U23>-0.01116</PDBx:U23>
         <PDBx:U33>0.36282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2725">
         <PDBx:U11>0.26821</PDBx:U11>
         <PDBx:U12>0.00616</PDBx:U12>
         <PDBx:U13>0.14030</PDBx:U13>
         <PDBx:U22>0.31687</PDBx:U22>
         <PDBx:U23>-0.01143</PDBx:U23>
         <PDBx:U33>0.39932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2726">
         <PDBx:U11>0.30365</PDBx:U11>
         <PDBx:U12>-0.00578</PDBx:U12>
         <PDBx:U13>0.13199</PDBx:U13>
         <PDBx:U22>0.33410</PDBx:U22>
         <PDBx:U23>-0.01299</PDBx:U23>
         <PDBx:U33>0.40240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2727">
         <PDBx:U11>0.28370</PDBx:U11>
         <PDBx:U12>-0.00558</PDBx:U12>
         <PDBx:U13>0.11510</PDBx:U13>
         <PDBx:U22>0.32500</PDBx:U22>
         <PDBx:U23>-0.00963</PDBx:U23>
         <PDBx:U33>0.38494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2728">
         <PDBx:U11>0.32477</PDBx:U11>
         <PDBx:U12>-0.01644</PDBx:U12>
         <PDBx:U13>0.13950</PDBx:U13>
         <PDBx:U22>0.32410</PDBx:U22>
         <PDBx:U23>-0.01757</PDBx:U23>
         <PDBx:U33>0.38714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2729">
         <PDBx:U11>0.33468</PDBx:U11>
         <PDBx:U12>-0.01571</PDBx:U12>
         <PDBx:U13>0.10693</PDBx:U13>
         <PDBx:U22>0.35587</PDBx:U22>
         <PDBx:U23>-0.01122</PDBx:U23>
         <PDBx:U33>0.40525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2730">
         <PDBx:U11>0.37135</PDBx:U11>
         <PDBx:U12>-0.02635</PDBx:U12>
         <PDBx:U13>0.13038</PDBx:U13>
         <PDBx:U22>0.35067</PDBx:U22>
         <PDBx:U23>-0.01793</PDBx:U23>
         <PDBx:U33>0.40232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2731">
         <PDBx:U11>0.32967</PDBx:U11>
         <PDBx:U12>-0.02560</PDBx:U12>
         <PDBx:U13>0.11420</PDBx:U13>
         <PDBx:U22>0.31961</PDBx:U22>
         <PDBx:U23>-0.01485</PDBx:U23>
         <PDBx:U33>0.36566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>306</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2732">
         <PDBx:U11>0.21953</PDBx:U11>
         <PDBx:U12>0.03389</PDBx:U12>
         <PDBx:U13>0.12640</PDBx:U13>
         <PDBx:U22>0.27785</PDBx:U22>
         <PDBx:U23>-0.00253</PDBx:U23>
         <PDBx:U33>0.37493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2733">
         <PDBx:U11>0.30776</PDBx:U11>
         <PDBx:U12>0.03915</PDBx:U12>
         <PDBx:U13>0.12823</PDBx:U13>
         <PDBx:U22>0.35584</PDBx:U22>
         <PDBx:U23>-0.00226</PDBx:U23>
         <PDBx:U33>0.46219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2734">
         <PDBx:U11>0.25032</PDBx:U11>
         <PDBx:U12>0.04342</PDBx:U12>
         <PDBx:U13>0.11993</PDBx:U13>
         <PDBx:U22>0.28600</PDBx:U22>
         <PDBx:U23>0.00062</PDBx:U23>
         <PDBx:U33>0.38715</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2735">
         <PDBx:U11>0.21475</PDBx:U11>
         <PDBx:U12>0.04202</PDBx:U12>
         <PDBx:U13>0.12531</PDBx:U13>
         <PDBx:U22>0.23104</PDBx:U22>
         <PDBx:U23>-0.00230</PDBx:U23>
         <PDBx:U33>0.33725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2736">
         <PDBx:U11>0.29662</PDBx:U11>
         <PDBx:U12>0.04713</PDBx:U12>
         <PDBx:U13>0.12390</PDBx:U13>
         <PDBx:U22>0.36411</PDBx:U22>
         <PDBx:U23>0.00209</PDBx:U23>
         <PDBx:U33>0.47882</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2737">
         <PDBx:U11>0.31298</PDBx:U11>
         <PDBx:U12>0.05170</PDBx:U12>
         <PDBx:U13>0.12813</PDBx:U13>
         <PDBx:U22>0.36815</PDBx:U22>
         <PDBx:U23>0.00208</PDBx:U23>
         <PDBx:U33>0.49545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2738">
         <PDBx:U11>0.33289</PDBx:U11>
         <PDBx:U12>0.04877</PDBx:U12>
         <PDBx:U13>0.14118</PDBx:U13>
         <PDBx:U22>0.37969</PDBx:U22>
         <PDBx:U23>-0.00338</PDBx:U23>
         <PDBx:U33>0.51786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2739">
         <PDBx:U11>0.26457</PDBx:U11>
         <PDBx:U12>0.05756</PDBx:U12>
         <PDBx:U13>0.11932</PDBx:U13>
         <PDBx:U22>0.31737</PDBx:U22>
         <PDBx:U23>0.00728</PDBx:U23>
         <PDBx:U33>0.44414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>307</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2740">
         <PDBx:U11>0.16741</PDBx:U11>
         <PDBx:U12>0.04826</PDBx:U12>
         <PDBx:U13>0.10685</PDBx:U13>
         <PDBx:U22>0.21450</PDBx:U22>
         <PDBx:U23>0.00602</PDBx:U23>
         <PDBx:U33>0.30529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2741">
         <PDBx:U11>0.21806</PDBx:U11>
         <PDBx:U12>0.05187</PDBx:U12>
         <PDBx:U13>0.09904</PDBx:U13>
         <PDBx:U22>0.25542</PDBx:U22>
         <PDBx:U23>0.00849</PDBx:U23>
         <PDBx:U33>0.33978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2742">
         <PDBx:U11>0.26723</PDBx:U11>
         <PDBx:U12>0.04627</PDBx:U12>
         <PDBx:U13>0.10514</PDBx:U13>
         <PDBx:U22>0.28261</PDBx:U22>
         <PDBx:U23>0.00265</PDBx:U23>
         <PDBx:U33>0.36247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2743">
         <PDBx:U11>0.24312</PDBx:U11>
         <PDBx:U12>0.04621</PDBx:U12>
         <PDBx:U13>0.10608</PDBx:U13>
         <PDBx:U22>0.24241</PDBx:U22>
         <PDBx:U23>0.00100</PDBx:U23>
         <PDBx:U33>0.32411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2744">
         <PDBx:U11>0.15812</PDBx:U11>
         <PDBx:U12>0.05755</PDBx:U12>
         <PDBx:U13>0.08440</PDBx:U13>
         <PDBx:U22>0.21221</PDBx:U22>
         <PDBx:U23>0.01457</PDBx:U23>
         <PDBx:U33>0.28438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2745">
         <PDBx:U11>0.17937</PDBx:U11>
         <PDBx:U12>0.06112</PDBx:U12>
         <PDBx:U13>0.07562</PDBx:U13>
         <PDBx:U22>0.22677</PDBx:U22>
         <PDBx:U23>0.01717</PDBx:U23>
         <PDBx:U33>0.29022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2746">
         <PDBx:U11>0.16183</PDBx:U11>
         <PDBx:U12>0.06240</PDBx:U12>
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         <PDBx:U23>0.01896</PDBx:U23>
         <PDBx:U33>0.27285</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2747">
         <PDBx:U11>0.19800</PDBx:U11>
         <PDBx:U12>0.06574</PDBx:U12>
         <PDBx:U13>0.06169</PDBx:U13>
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         <PDBx:U23>0.02228</PDBx:U23>
         <PDBx:U33>0.31163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>308</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2748">
         <PDBx:U11>0.19451</PDBx:U11>
         <PDBx:U12>0.04021</PDBx:U12>
         <PDBx:U13>0.10771</PDBx:U13>
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         <PDBx:U23>-0.00072</PDBx:U23>
         <PDBx:U33>0.27956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.21340</PDBx:U11>
         <PDBx:U12>0.03118</PDBx:U12>
         <PDBx:U13>0.10570</PDBx:U13>
         <PDBx:U22>0.19924</PDBx:U22>
         <PDBx:U23>-0.00597</PDBx:U23>
         <PDBx:U33>0.26206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.22702</PDBx:U11>
         <PDBx:U12>0.02588</PDBx:U12>
         <PDBx:U13>0.12086</PDBx:U13>
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         <PDBx:U23>-0.01208</PDBx:U23>
         <PDBx:U33>0.26406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.27084</PDBx:U11>
         <PDBx:U12>0.02338</PDBx:U12>
         <PDBx:U13>0.11757</PDBx:U13>
         <PDBx:U22>0.21583</PDBx:U22>
         <PDBx:U23>-0.01477</PDBx:U23>
         <PDBx:U33>0.28276</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2752">
         <PDBx:U11>0.23961</PDBx:U11>
         <PDBx:U12>0.02180</PDBx:U12>
         <PDBx:U13>0.10245</PDBx:U13>
         <PDBx:U22>0.22174</PDBx:U22>
         <PDBx:U23>-0.00793</PDBx:U23>
         <PDBx:U33>0.27522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2753">
         <PDBx:U11>0.19223</PDBx:U11>
         <PDBx:U12>0.02644</PDBx:U12>
         <PDBx:U13>0.08531</PDBx:U13>
         <PDBx:U22>0.18764</PDBx:U22>
         <PDBx:U23>-0.00359</PDBx:U23>
         <PDBx:U33>0.23053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2754">
         <PDBx:U11>0.26017</PDBx:U11>
         <PDBx:U12>0.01133</PDBx:U12>
         <PDBx:U13>0.10368</PDBx:U13>
         <PDBx:U22>0.21066</PDBx:U22>
         <PDBx:U23>-0.01313</PDBx:U23>
         <PDBx:U33>0.25689</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2755">
         <PDBx:U11>0.27711</PDBx:U11>
         <PDBx:U12>0.01662</PDBx:U12>
         <PDBx:U13>0.08255</PDBx:U13>
         <PDBx:U22>0.26974</PDBx:U22>
         <PDBx:U23>-0.00555</PDBx:U23>
         <PDBx:U33>0.30674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>309</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2756">
         <PDBx:U11>0.21322</PDBx:U11>
         <PDBx:U12>0.02362</PDBx:U12>
         <PDBx:U13>0.13488</PDBx:U13>
         <PDBx:U22>0.18465</PDBx:U22>
         <PDBx:U23>-0.01442</PDBx:U23>
         <PDBx:U33>0.26778</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2757">
         <PDBx:U11>0.25125</PDBx:U11>
         <PDBx:U12>0.01719</PDBx:U12>
         <PDBx:U13>0.14537</PDBx:U13>
         <PDBx:U22>0.20164</PDBx:U22>
         <PDBx:U23>-0.02039</PDBx:U23>
         <PDBx:U33>0.29059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.31177</PDBx:U11>
         <PDBx:U12>0.02309</PDBx:U12>
         <PDBx:U13>0.14185</PDBx:U13>
         <PDBx:U22>0.25577</PDBx:U22>
         <PDBx:U23>-0.01920</PDBx:U23>
         <PDBx:U33>0.35214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.33145</PDBx:U11>
         <PDBx:U12>0.01767</PDBx:U12>
         <PDBx:U13>0.14637</PDBx:U13>
         <PDBx:U22>0.25219</PDBx:U22>
         <PDBx:U23>-0.02454</PDBx:U23>
         <PDBx:U33>0.34798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.29990</PDBx:U11>
         <PDBx:U12>0.01385</PDBx:U12>
         <PDBx:U13>0.15622</PDBx:U13>
         <PDBx:U22>0.25898</PDBx:U22>
         <PDBx:U23>-0.02260</PDBx:U23>
         <PDBx:U33>0.35812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.00806</PDBx:U12>
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         <PDBx:U23>-0.02905</PDBx:U23>
         <PDBx:U33>0.42264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.64970</PDBx:U11>
         <PDBx:U12>0.00529</PDBx:U12>
         <PDBx:U13>0.17942</PDBx:U13>
         <PDBx:U22>0.59853</PDBx:U22>
         <PDBx:U23>-0.03179</PDBx:U23>
         <PDBx:U33>0.71351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>310</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.01030</PDBx:U23>
         <PDBx:U33>0.32096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.01091</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.00230</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.00575</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.00463</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.00092</PDBx:U23>
         <PDBx:U33>0.57391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>311</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>312</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.00908</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>312</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.26051</PDBx:U11>
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         <PDBx:U23>0.00363</PDBx:U23>
         <PDBx:U33>0.30842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>312</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.28368</PDBx:U11>
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         <PDBx:U23>0.00711</PDBx:U23>
         <PDBx:U33>0.32869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>312</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U11>0.30466</PDBx:U11>
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         <PDBx:U23>0.01586</PDBx:U23>
         <PDBx:U33>0.37137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>312</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.02086</PDBx:U12>
         <PDBx:U13>0.11450</PDBx:U13>
         <PDBx:U22>0.18782</PDBx:U22>
         <PDBx:U23>-0.02108</PDBx:U23>
         <PDBx:U33>0.25532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.32487</PDBx:U11>
         <PDBx:U12>0.00979</PDBx:U12>
         <PDBx:U13>0.11624</PDBx:U13>
         <PDBx:U22>0.20314</PDBx:U22>
         <PDBx:U23>-0.02751</PDBx:U23>
         <PDBx:U33>0.26222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.00504</PDBx:U12>
         <PDBx:U13>0.13263</PDBx:U13>
         <PDBx:U22>0.20197</PDBx:U22>
         <PDBx:U23>-0.03462</PDBx:U23>
         <PDBx:U33>0.27108</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.00538</PDBx:U12>
         <PDBx:U13>0.13958</PDBx:U13>
         <PDBx:U22>0.21435</PDBx:U22>
         <PDBx:U23>-0.04017</PDBx:U23>
         <PDBx:U33>0.27731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2786">
         <PDBx:U11>0.32272</PDBx:U11>
         <PDBx:U12>0.00233</PDBx:U12>
         <PDBx:U13>0.11786</PDBx:U13>
         <PDBx:U22>0.19680</PDBx:U22>
         <PDBx:U23>-0.02798</PDBx:U23>
         <PDBx:U33>0.24691</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2787">
         <PDBx:U11>0.31387</PDBx:U11>
         <PDBx:U12>0.00612</PDBx:U12>
         <PDBx:U13>0.10090</PDBx:U13>
         <PDBx:U22>0.19945</PDBx:U22>
         <PDBx:U23>-0.02243</PDBx:U23>
         <PDBx:U33>0.23978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2788">
         <PDBx:U11>0.34142</PDBx:U11>
         <PDBx:U12>-0.00349</PDBx:U12>
         <PDBx:U13>0.10196</PDBx:U13>
         <PDBx:U22>0.21590</PDBx:U22>
         <PDBx:U23>-0.02341</PDBx:U23>
         <PDBx:U33>0.24850</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2789">
         <PDBx:U11>0.33813</PDBx:U11>
         <PDBx:U12>0.00990</PDBx:U12>
         <PDBx:U13>0.08332</PDBx:U13>
         <PDBx:U22>0.21677</PDBx:U22>
         <PDBx:U23>-0.02105</PDBx:U23>
         <PDBx:U33>0.24886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>313</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2790">
         <PDBx:U11>0.31743</PDBx:U11>
         <PDBx:U12>0.01158</PDBx:U12>
         <PDBx:U13>0.13657</PDBx:U13>
         <PDBx:U22>0.18796</PDBx:U22>
         <PDBx:U23>-0.03320</PDBx:U23>
         <PDBx:U33>0.27193</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2791">
         <PDBx:U11>0.31866</PDBx:U11>
         <PDBx:U12>0.01157</PDBx:U12>
         <PDBx:U13>0.13650</PDBx:U13>
         <PDBx:U22>0.18905</PDBx:U22>
         <PDBx:U23>-0.03323</PDBx:U23>
         <PDBx:U33>0.27295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2792">
         <PDBx:U11>0.34593</PDBx:U11>
         <PDBx:U12>0.00655</PDBx:U12>
         <PDBx:U13>0.14447</PDBx:U13>
         <PDBx:U22>0.20068</PDBx:U22>
         <PDBx:U23>-0.03814</PDBx:U23>
         <PDBx:U33>0.29345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2793">
         <PDBx:U11>0.34539</PDBx:U11>
         <PDBx:U12>0.00648</PDBx:U12>
         <PDBx:U13>0.14458</PDBx:U13>
         <PDBx:U22>0.20012</PDBx:U22>
         <PDBx:U23>-0.03816</PDBx:U23>
         <PDBx:U33>0.29286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2794">
         <PDBx:U11>0.37475</PDBx:U11>
         <PDBx:U12>-0.00061</PDBx:U12>
         <PDBx:U13>0.13725</PDBx:U13>
         <PDBx:U22>0.20363</PDBx:U22>
         <PDBx:U23>-0.04372</PDBx:U23>
         <PDBx:U33>0.28561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2795">
         <PDBx:U11>0.37237</PDBx:U11>
         <PDBx:U12>-0.00054</PDBx:U12>
         <PDBx:U13>0.13738</PDBx:U13>
         <PDBx:U22>0.20137</PDBx:U22>
         <PDBx:U23>-0.04372</PDBx:U23>
         <PDBx:U33>0.28369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2796">
         <PDBx:U11>0.34757</PDBx:U11>
         <PDBx:U12>0.00280</PDBx:U12>
         <PDBx:U13>0.12346</PDBx:U13>
         <PDBx:U22>0.17722</PDBx:U22>
         <PDBx:U23>-0.04185</PDBx:U23>
         <PDBx:U33>0.25358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2797">
         <PDBx:U11>0.35535</PDBx:U11>
         <PDBx:U12>0.00305</PDBx:U12>
         <PDBx:U13>0.12391</PDBx:U13>
         <PDBx:U22>0.18516</PDBx:U22>
         <PDBx:U23>-0.04192</PDBx:U23>
         <PDBx:U33>0.26251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2798">
         <PDBx:U11>0.29845</PDBx:U11>
         <PDBx:U12>0.01508</PDBx:U12>
         <PDBx:U13>0.14526</PDBx:U13>
         <PDBx:U22>0.16704</PDBx:U22>
         <PDBx:U23>-0.03379</PDBx:U23>
         <PDBx:U33>0.27700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2799">
         <PDBx:U11>0.30294</PDBx:U11>
         <PDBx:U12>0.01498</PDBx:U12>
         <PDBx:U13>0.14573</PDBx:U13>
         <PDBx:U22>0.17180</PDBx:U22>
         <PDBx:U23>-0.03381</PDBx:U23>
         <PDBx:U33>0.28196</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2800">
         <PDBx:U11>0.34679</PDBx:U11>
         <PDBx:U12>0.01135</PDBx:U12>
         <PDBx:U13>0.14907</PDBx:U13>
         <PDBx:U22>0.19651</PDBx:U22>
         <PDBx:U23>-0.03889</PDBx:U23>
         <PDBx:U33>0.31500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2801">
         <PDBx:U11>0.37106</PDBx:U11>
         <PDBx:U12>0.01080</PDBx:U12>
         <PDBx:U13>0.15256</PDBx:U13>
         <PDBx:U22>0.22166</PDBx:U22>
         <PDBx:U23>-0.03920</PDBx:U23>
         <PDBx:U33>0.34208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2802">
         <PDBx:U11>0.47985</PDBx:U11>
         <PDBx:U12>0.00476</PDBx:U12>
         <PDBx:U13>0.16304</PDBx:U13>
         <PDBx:U22>0.31654</PDBx:U22>
         <PDBx:U23>-0.04480</PDBx:U23>
         <PDBx:U33>0.44195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2803">
         <PDBx:U11>0.47527</PDBx:U11>
         <PDBx:U12>0.00247</PDBx:U12>
         <PDBx:U13>0.16579</PDBx:U13>
         <PDBx:U22>0.31173</PDBx:U22>
         <PDBx:U23>-0.04567</PDBx:U23>
         <PDBx:U33>0.43371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2804">
         <PDBx:U11>0.47348</PDBx:U11>
         <PDBx:U12>0.00832</PDBx:U12>
         <PDBx:U13>0.17086</PDBx:U13>
         <PDBx:U22>0.32328</PDBx:U22>
         <PDBx:U23>-0.04258</PDBx:U23>
         <PDBx:U33>0.45878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2805">
         <PDBx:U11>0.47190</PDBx:U11>
         <PDBx:U12>0.00310</PDBx:U12>
         <PDBx:U13>0.17248</PDBx:U13>
         <PDBx:U22>0.31973</PDBx:U22>
         <PDBx:U23>-0.04439</PDBx:U23>
         <PDBx:U33>0.44435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2806">
         <PDBx:U11>0.48371</PDBx:U11>
         <PDBx:U12>-0.00390</PDBx:U12>
         <PDBx:U13>0.16531</PDBx:U13>
         <PDBx:U22>0.29732</PDBx:U22>
         <PDBx:U23>-0.05179</PDBx:U23>
         <PDBx:U33>0.41769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2807">
         <PDBx:U11>0.50787</PDBx:U11>
         <PDBx:U12>-0.00505</PDBx:U12>
         <PDBx:U13>0.16914</PDBx:U13>
         <PDBx:U22>0.32217</PDBx:U22>
         <PDBx:U23>-0.05224</PDBx:U23>
         <PDBx:U33>0.44240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>314</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2808">
         <PDBx:U11>0.40531</PDBx:U11>
         <PDBx:U12>-0.01112</PDBx:U12>
         <PDBx:U13>0.14393</PDBx:U13>
         <PDBx:U22>0.21332</PDBx:U22>
         <PDBx:U23>-0.04949</PDBx:U23>
         <PDBx:U33>0.29136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2809">
         <PDBx:U11>0.41434</PDBx:U11>
         <PDBx:U12>-0.01920</PDBx:U12>
         <PDBx:U13>0.13384</PDBx:U13>
         <PDBx:U22>0.19867</PDBx:U22>
         <PDBx:U23>-0.05369</PDBx:U23>
         <PDBx:U33>0.26372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2810">
         <PDBx:U11>0.37445</PDBx:U11>
         <PDBx:U12>-0.01624</PDBx:U12>
         <PDBx:U13>0.12756</PDBx:U13>
         <PDBx:U22>0.15659</PDBx:U22>
         <PDBx:U23>-0.05542</PDBx:U23>
         <PDBx:U33>0.22993</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2811">
         <PDBx:U11>0.40742</PDBx:U11>
         <PDBx:U12>-0.01712</PDBx:U12>
         <PDBx:U13>0.11221</PDBx:U13>
         <PDBx:U22>0.18262</PDBx:U22>
         <PDBx:U23>-0.05607</PDBx:U23>
         <PDBx:U33>0.24799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2812">
         <PDBx:U11>0.42620</PDBx:U11>
         <PDBx:U12>-0.03086</PDBx:U12>
         <PDBx:U13>0.14304</PDBx:U13>
         <PDBx:U22>0.19032</PDBx:U22>
         <PDBx:U23>-0.05837</PDBx:U23>
         <PDBx:U33>0.24959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2813">
         <PDBx:U11>0.43447</PDBx:U11>
         <PDBx:U12>-0.03844</PDBx:U12>
         <PDBx:U13>0.14409</PDBx:U13>
         <PDBx:U22>0.18986</PDBx:U22>
         <PDBx:U23>-0.05717</PDBx:U23>
         <PDBx:U33>0.23572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2814">
         <PDBx:U11>0.58896</PDBx:U11>
         <PDBx:U12>-0.04090</PDBx:U12>
         <PDBx:U13>0.12800</PDBx:U13>
         <PDBx:U22>0.33540</PDBx:U22>
         <PDBx:U23>-0.05433</PDBx:U23>
         <PDBx:U33>0.36513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2815">
         <PDBx:U11>0.50370</PDBx:U11>
         <PDBx:U12>-0.04380</PDBx:U12>
         <PDBx:U13>0.16071</PDBx:U13>
         <PDBx:U22>0.25756</PDBx:U22>
         <PDBx:U23>-0.05907</PDBx:U23>
         <PDBx:U33>0.30839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2816">
         <PDBx:U11>0.57752</PDBx:U11>
         <PDBx:U12>-0.04890</PDBx:U12>
         <PDBx:U13>0.12900</PDBx:U13>
         <PDBx:U22>0.31250</PDBx:U22>
         <PDBx:U23>-0.05244</PDBx:U23>
         <PDBx:U33>0.33155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2817">
         <PDBx:U11>0.46791</PDBx:U11>
         <PDBx:U12>-0.05241</PDBx:U12>
         <PDBx:U13>0.16274</PDBx:U13>
         <PDBx:U22>0.21146</PDBx:U22>
         <PDBx:U23>-0.05818</PDBx:U23>
         <PDBx:U33>0.25165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2818">
         <PDBx:U11>0.53435</PDBx:U11>
         <PDBx:U12>-0.05528</PDBx:U12>
         <PDBx:U13>0.14720</PDBx:U13>
         <PDBx:U22>0.26745</PDBx:U22>
         <PDBx:U23>-0.05453</PDBx:U23>
         <PDBx:U33>0.29191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2819">
         <PDBx:U11>0.57493</PDBx:U11>
         <PDBx:U12>-0.06449</PDBx:U12>
         <PDBx:U13>0.14959</PDBx:U13>
         <PDBx:U22>0.29546</PDBx:U22>
         <PDBx:U23>-0.05301</PDBx:U23>
         <PDBx:U33>0.31145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>315</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2820">
         <PDBx:U11>0.38676</PDBx:U11>
         <PDBx:U12>-0.01349</PDBx:U12>
         <PDBx:U13>0.13854</PDBx:U13>
         <PDBx:U22>0.17336</PDBx:U22>
         <PDBx:U23>-0.05632</PDBx:U23>
         <PDBx:U33>0.26365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>316</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2821">
         <PDBx:U11>0.38913</PDBx:U11>
         <PDBx:U12>-0.01303</PDBx:U12>
         <PDBx:U13>0.13414</PDBx:U13>
         <PDBx:U22>0.16975</PDBx:U22>
         <PDBx:U23>-0.05860</PDBx:U23>
         <PDBx:U33>0.26956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>316</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2822">
         <PDBx:U11>0.38068</PDBx:U11>
         <PDBx:U12>-0.00281</PDBx:U12>
         <PDBx:U13>0.12631</PDBx:U13>
         <PDBx:U22>0.17925</PDBx:U22>
         <PDBx:U23>-0.05245</PDBx:U23>
         <PDBx:U33>0.28717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>316</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2823">
         <PDBx:U11>0.34320</PDBx:U11>
         <PDBx:U12>0.00622</PDBx:U12>
         <PDBx:U13>0.13202</PDBx:U13>
         <PDBx:U22>0.16240</PDBx:U22>
         <PDBx:U23>-0.04586</PDBx:U23>
         <PDBx:U33>0.28007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>316</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2824">
         <PDBx:U11>0.38720</PDBx:U11>
         <PDBx:U12>-0.01306</PDBx:U12>
         <PDBx:U13>0.14833</PDBx:U13>
         <PDBx:U22>0.16467</PDBx:U22>
         <PDBx:U23>-0.06107</PDBx:U23>
         <PDBx:U33>0.28135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>316</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2825">
         <PDBx:U11>0.43058</PDBx:U11>
         <PDBx:U12>-0.01464</PDBx:U12>
         <PDBx:U13>0.14409</PDBx:U13>
         <PDBx:U22>0.19812</PDBx:U22>
         <PDBx:U23>-0.06420</PDBx:U23>
         <PDBx:U33>0.32512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>316</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2826">
         <PDBx:U11>0.47850</PDBx:U11>
         <PDBx:U12>-0.00743</PDBx:U12>
         <PDBx:U13>0.14052</PDBx:U13>
         <PDBx:U22>0.25769</PDBx:U22>
         <PDBx:U23>-0.05928</PDBx:U23>
         <PDBx:U33>0.39750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>316</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2827">
         <PDBx:U11>0.57596</PDBx:U11>
         <PDBx:U12>-0.02385</PDBx:U12>
         <PDBx:U13>0.14399</PDBx:U13>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>319</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2844">
         <PDBx:U11>0.32483</PDBx:U11>
         <PDBx:U12>0.01657</PDBx:U12>
         <PDBx:U13>0.16140</PDBx:U13>
         <PDBx:U22>0.16082</PDBx:U22>
         <PDBx:U23>-0.03989</PDBx:U23>
         <PDBx:U33>0.32468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>319</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2845">
         <PDBx:U11>0.45340</PDBx:U11>
         <PDBx:U12>0.00991</PDBx:U12>
         <PDBx:U13>0.17078</PDBx:U13>
         <PDBx:U22>0.26661</PDBx:U22>
         <PDBx:U23>-0.04831</PDBx:U23>
         <PDBx:U33>0.43902</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>319</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2846">
         <PDBx:U11>0.44251</PDBx:U11>
         <PDBx:U12>0.00445</PDBx:U12>
         <PDBx:U13>0.18213</PDBx:U13>
         <PDBx:U22>0.24872</PDBx:U22>
         <PDBx:U23>-0.05395</PDBx:U23>
         <PDBx:U33>0.41692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>319</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2847">
         <PDBx:U11>0.67183</PDBx:U11>
         <PDBx:U12>-0.00185</PDBx:U12>
         <PDBx:U13>0.19218</PDBx:U13>
         <PDBx:U22>0.45554</PDBx:U22>
         <PDBx:U23>-0.06259</PDBx:U23>
         <PDBx:U33>0.63114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>319</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2848">
         <PDBx:U11>0.75404</PDBx:U11>
         <PDBx:U12>-0.00973</PDBx:U12>
         <PDBx:U13>0.20227</PDBx:U13>
         <PDBx:U22>0.52667</PDBx:U22>
         <PDBx:U23>-0.06903</PDBx:U23>
         <PDBx:U33>0.69348</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>319</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2849">
         <PDBx:U11>0.27125</PDBx:U11>
         <PDBx:U12>0.02733</PDBx:U12>
         <PDBx:U13>0.13432</PDBx:U13>
         <PDBx:U22>0.14015</PDBx:U22>
         <PDBx:U23>-0.02670</PDBx:U23>
         <PDBx:U33>0.28026</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2850">
         <PDBx:U11>0.24857</PDBx:U11>
         <PDBx:U12>0.03288</PDBx:U12>
         <PDBx:U13>0.12648</PDBx:U13>
         <PDBx:U22>0.13812</PDBx:U22>
         <PDBx:U23>-0.02040</PDBx:U23>
         <PDBx:U33>0.26599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2851">
         <PDBx:U11>0.23100</PDBx:U11>
         <PDBx:U12>0.04182</PDBx:U12>
         <PDBx:U13>0.12004</PDBx:U13>
         <PDBx:U22>0.14391</PDBx:U22>
         <PDBx:U23>-0.00943</PDBx:U23>
         <PDBx:U33>0.27631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2852">
         <PDBx:U11>0.25951</PDBx:U11>
         <PDBx:U12>0.04376</PDBx:U12>
         <PDBx:U13>0.11847</PDBx:U13>
         <PDBx:U22>0.17088</PDBx:U22>
         <PDBx:U23>-0.00654</PDBx:U23>
         <PDBx:U33>0.31218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2853">
         <PDBx:U11>0.26685</PDBx:U11>
         <PDBx:U12>0.02961</PDBx:U12>
         <PDBx:U13>0.11495</PDBx:U13>
         <PDBx:U22>0.14982</PDBx:U22>
         <PDBx:U23>-0.02312</PDBx:U23>
         <PDBx:U33>0.26069</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2854">
         <PDBx:U11>0.23249</PDBx:U11>
         <PDBx:U12>0.03261</PDBx:U12>
         <PDBx:U13>0.10578</PDBx:U13>
         <PDBx:U22>0.13229</PDBx:U22>
         <PDBx:U23>-0.01834</PDBx:U23>
         <PDBx:U33>0.22706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2855">
         <PDBx:U11>0.26735</PDBx:U11>
         <PDBx:U12>0.02724</PDBx:U12>
         <PDBx:U13>0.09068</PDBx:U13>
         <PDBx:U22>0.15859</PDBx:U22>
         <PDBx:U23>-0.02059</PDBx:U23>
         <PDBx:U33>0.23531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2856">
         <PDBx:U11>0.29317</PDBx:U11>
         <PDBx:U12>0.01681</PDBx:U12>
         <PDBx:U13>0.09439</PDBx:U13>
         <PDBx:U22>0.15713</PDBx:U22>
         <PDBx:U23>-0.02905</PDBx:U23>
         <PDBx:U33>0.23016</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2857">
         <PDBx:U11>0.33074</PDBx:U11>
         <PDBx:U12>0.01102</PDBx:U12>
         <PDBx:U13>0.08289</PDBx:U13>
         <PDBx:U22>0.18012</PDBx:U22>
         <PDBx:U23>-0.03255</PDBx:U23>
         <PDBx:U33>0.24411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2858">
         <PDBx:U11>0.28139</PDBx:U11>
         <PDBx:U12>0.01507</PDBx:U12>
         <PDBx:U13>0.06796</PDBx:U13>
         <PDBx:U22>0.14323</PDBx:U22>
         <PDBx:U23>-0.02871</PDBx:U23>
         <PDBx:U33>0.20217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2859">
         <PDBx:U11>0.38969</PDBx:U11>
         <PDBx:U12>0.00118</PDBx:U12>
         <PDBx:U13>0.08608</PDBx:U13>
         <PDBx:U22>0.21285</PDBx:U22>
         <PDBx:U23>-0.03987</PDBx:U23>
         <PDBx:U33>0.27215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>465</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>320</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2860">
         <PDBx:U11>0.30529</PDBx:U11>
         <PDBx:U12>0.04601</PDBx:U12>
         <PDBx:U13>0.11601</PDBx:U13>
         <PDBx:U22>0.23834</PDBx:U22>
         <PDBx:U23>-0.00353</PDBx:U23>
         <PDBx:U33>0.36393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2861">
         <PDBx:U11>0.24749</PDBx:U11>
         <PDBx:U12>0.05284</PDBx:U12>
         <PDBx:U13>0.10776</PDBx:U13>
         <PDBx:U22>0.20129</PDBx:U22>
         <PDBx:U23>0.00667</PDBx:U23>
         <PDBx:U33>0.32606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2862">
         <PDBx:U11>0.22911</PDBx:U11>
         <PDBx:U12>0.05515</PDBx:U12>
         <PDBx:U13>0.09837</PDBx:U13>
         <PDBx:U22>0.18825</PDBx:U22>
         <PDBx:U23>0.01002</PDBx:U23>
         <PDBx:U33>0.30364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2863">
         <PDBx:U11>0.19474</PDBx:U11>
         <PDBx:U12>0.05396</PDBx:U12>
         <PDBx:U13>0.09491</PDBx:U13>
         <PDBx:U22>0.14919</PDBx:U22>
         <PDBx:U23>0.00566</PDBx:U23>
         <PDBx:U33>0.25438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2864">
         <PDBx:U11>0.18210</PDBx:U11>
         <PDBx:U12>0.05531</PDBx:U12>
         <PDBx:U13>0.10355</PDBx:U13>
         <PDBx:U22>0.15399</PDBx:U22>
         <PDBx:U23>0.00999</PDBx:U23>
         <PDBx:U33>0.27005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2865">
         <PDBx:U11>0.19901</PDBx:U11>
         <PDBx:U12>0.06119</PDBx:U12>
         <PDBx:U13>0.09591</PDBx:U13>
         <PDBx:U22>0.18860</PDBx:U22>
         <PDBx:U23>0.01930</PDBx:U23>
         <PDBx:U33>0.30409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2866">
         <PDBx:U11>0.20854</PDBx:U11>
         <PDBx:U12>0.05442</PDBx:U12>
         <PDBx:U13>0.09746</PDBx:U13>
         <PDBx:U22>0.18465</PDBx:U22>
         <PDBx:U23>0.00788</PDBx:U23>
         <PDBx:U33>0.28371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2867">
         <PDBx:U11>0.19636</PDBx:U11>
         <PDBx:U12>0.06316</PDBx:U12>
         <PDBx:U13>0.09185</PDBx:U13>
         <PDBx:U22>0.20262</PDBx:U22>
         <PDBx:U23>0.02109</PDBx:U23>
         <PDBx:U33>0.31088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>321</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2868">
         <PDBx:U11>0.17621</PDBx:U11>
         <PDBx:U12>0.05855</PDBx:U12>
         <PDBx:U13>0.09499</PDBx:U13>
         <PDBx:U22>0.14348</PDBx:U22>
         <PDBx:U23>0.01758</PDBx:U23>
         <PDBx:U33>0.26315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>322</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2869">
         <PDBx:U11>0.16474</PDBx:U11>
         <PDBx:U12>0.06093</PDBx:U12>
         <PDBx:U13>0.08611</PDBx:U13>
         <PDBx:U22>0.14246</PDBx:U22>
         <PDBx:U23>0.02209</PDBx:U23>
         <PDBx:U33>0.25118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>322</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2870">
         <PDBx:U11>0.19631</PDBx:U11>
         <PDBx:U12>0.06425</PDBx:U12>
         <PDBx:U13>0.07589</PDBx:U13>
         <PDBx:U22>0.19465</PDBx:U22>
         <PDBx:U23>0.02771</PDBx:U23>
         <PDBx:U33>0.28540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>322</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2871">
         <PDBx:U11>0.18516</PDBx:U11>
         <PDBx:U12>0.06524</PDBx:U12>
         <PDBx:U13>0.07564</PDBx:U13>
         <PDBx:U22>0.18982</PDBx:U22>
         <PDBx:U23>0.02930</PDBx:U23>
         <PDBx:U33>0.27997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>322</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2872">
         <PDBx:U11>0.24722</PDBx:U11>
         <PDBx:U12>0.06179</PDBx:U12>
         <PDBx:U13>0.08883</PDBx:U13>
         <PDBx:U22>0.22256</PDBx:U22>
         <PDBx:U23>0.02774</PDBx:U23>
         <PDBx:U33>0.34396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>322</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2873">
         <PDBx:U11>0.23542</PDBx:U11>
         <PDBx:U12>0.06498</PDBx:U12>
         <PDBx:U13>0.08805</PDBx:U13>
         <PDBx:U22>0.21969</PDBx:U22>
         <PDBx:U23>0.03592</PDBx:U23>
         <PDBx:U33>0.34368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>322</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2874">
         <PDBx:U11>0.29586</PDBx:U11>
         <PDBx:U12>0.05781</PDBx:U12>
         <PDBx:U13>0.09975</PDBx:U13>
         <PDBx:U22>0.24769</PDBx:U22>
         <PDBx:U23>0.02101</PDBx:U23>
         <PDBx:U33>0.39041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>322</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2875">
         <PDBx:U11>0.15818</PDBx:U11>
         <PDBx:U12>0.06582</PDBx:U12>
         <PDBx:U13>0.06751</PDBx:U13>
         <PDBx:U22>0.16671</PDBx:U22>
         <PDBx:U23>0.02964</PDBx:U23>
         <PDBx:U33>0.24293</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2876">
         <PDBx:U11>0.13106</PDBx:U11>
         <PDBx:U12>0.06800</PDBx:U12>
         <PDBx:U13>0.05849</PDBx:U13>
         <PDBx:U22>0.15574</PDBx:U22>
         <PDBx:U23>0.03316</PDBx:U23>
         <PDBx:U33>0.21507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2877">
         <PDBx:U11>0.13221</PDBx:U11>
         <PDBx:U12>0.06993</PDBx:U12>
         <PDBx:U13>0.05833</PDBx:U13>
         <PDBx:U22>0.16404</PDBx:U22>
         <PDBx:U23>0.04132</PDBx:U23>
         <PDBx:U33>0.22592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2878">
         <PDBx:U11>0.15376</PDBx:U11>
         <PDBx:U12>0.07158</PDBx:U12>
         <PDBx:U13>0.05374</PDBx:U13>
         <PDBx:U22>0.19509</PDBx:U22>
         <PDBx:U23>0.04359</PDBx:U23>
         <PDBx:U33>0.24913</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2879">
         <PDBx:U11>0.12404</PDBx:U11>
         <PDBx:U12>0.06913</PDBx:U12>
         <PDBx:U13>0.05049</PDBx:U13>
         <PDBx:U22>0.15664</PDBx:U22>
         <PDBx:U23>0.03210</PDBx:U23>
         <PDBx:U33>0.20018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2880">
         <PDBx:U11>0.17375</PDBx:U11>
         <PDBx:U12>0.06942</PDBx:U12>
         <PDBx:U13>0.04881</PDBx:U13>
         <PDBx:U22>0.19904</PDBx:U22>
         <PDBx:U23>0.02480</PDBx:U23>
         <PDBx:U33>0.23883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2881">
         <PDBx:U11>0.16326</PDBx:U11>
         <PDBx:U12>0.07179</PDBx:U12>
         <PDBx:U13>0.03950</PDBx:U13>
         <PDBx:U22>0.19809</PDBx:U22>
         <PDBx:U23>0.02390</PDBx:U23>
         <PDBx:U33>0.22242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2882">
         <PDBx:U11>0.21063</PDBx:U11>
         <PDBx:U12>0.06909</PDBx:U12>
         <PDBx:U13>0.04988</PDBx:U13>
         <PDBx:U22>0.23275</PDBx:U22>
         <PDBx:U23>0.02183</PDBx:U23>
         <PDBx:U33>0.27126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>323</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2883">
         <PDBx:U11>0.17345</PDBx:U11>
         <PDBx:U12>0.07024</PDBx:U12>
         <PDBx:U13>0.06358</PDBx:U13>
         <PDBx:U22>0.20004</PDBx:U22>
         <PDBx:U23>0.04622</PDBx:U23>
         <PDBx:U33>0.27395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2884">
         <PDBx:U11>0.20111</PDBx:U11>
         <PDBx:U12>0.07316</PDBx:U12>
         <PDBx:U13>0.06453</PDBx:U13>
         <PDBx:U22>0.23186</PDBx:U22>
         <PDBx:U23>0.05526</PDBx:U23>
         <PDBx:U33>0.31052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2885">
         <PDBx:U11>0.24985</PDBx:U11>
         <PDBx:U12>0.07461</PDBx:U12>
         <PDBx:U13>0.06691</PDBx:U13>
         <PDBx:U22>0.27890</PDBx:U22>
         <PDBx:U23>0.05476</PDBx:U23>
         <PDBx:U33>0.36711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2886">
         <PDBx:U11>0.21178</PDBx:U11>
         <PDBx:U12>0.07776</PDBx:U12>
         <PDBx:U13>0.06262</PDBx:U13>
         <PDBx:U22>0.25060</PDBx:U22>
         <PDBx:U23>0.05976</PDBx:U23>
         <PDBx:U33>0.33358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2887">
         <PDBx:U11>0.25988</PDBx:U11>
         <PDBx:U12>0.07331</PDBx:U12>
         <PDBx:U13>0.07172</PDBx:U13>
         <PDBx:U22>0.28218</PDBx:U22>
         <PDBx:U23>0.06097</PDBx:U23>
         <PDBx:U33>0.37680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2888">
         <PDBx:U11>0.47693</PDBx:U11>
         <PDBx:U12>0.07717</PDBx:U12>
         <PDBx:U13>0.07403</PDBx:U13>
         <PDBx:U22>0.50053</PDBx:U22>
         <PDBx:U23>0.07172</PDBx:U23>
         <PDBx:U33>0.60355</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2889">
         <PDBx:U11>0.60999</PDBx:U11>
         <PDBx:U12>0.07704</PDBx:U12>
         <PDBx:U13>0.08254</PDBx:U13>
         <PDBx:U22>0.62252</PDBx:U22>
         <PDBx:U23>0.07767</PDBx:U23>
         <PDBx:U33>0.74532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2890">
         <PDBx:U11>0.80063</PDBx:U11>
         <PDBx:U12>0.08047</PDBx:U12>
         <PDBx:U13>0.08765</PDBx:U13>
         <PDBx:U22>0.80528</PDBx:U22>
         <PDBx:U23>0.08453</PDBx:U23>
         <PDBx:U33>0.94700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2891">
         <PDBx:U11>0.89237</PDBx:U11>
         <PDBx:U12>0.08420</PDBx:U12>
         <PDBx:U13>0.08821</PDBx:U13>
         <PDBx:U22>0.90005</PDBx:U22>
         <PDBx:U23>0.09676</PDBx:U23>
         <PDBx:U33>1.04434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2892">
         <PDBx:U11>0.91407</PDBx:U11>
         <PDBx:U12>0.08463</PDBx:U12>
         <PDBx:U13>0.08537</PDBx:U13>
         <PDBx:U22>0.93314</PDBx:U22>
         <PDBx:U23>0.10377</PDBx:U23>
         <PDBx:U33>1.06144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2893">
         <PDBx:U11>0.88409</PDBx:U11>
         <PDBx:U12>0.08791</PDBx:U12>
         <PDBx:U13>0.09186</PDBx:U13>
         <PDBx:U22>0.88337</PDBx:U22>
         <PDBx:U23>0.10213</PDBx:U23>
         <PDBx:U33>1.04605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>324</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2894">
         <PDBx:U11>0.15381</PDBx:U11>
         <PDBx:U12>0.07247</PDBx:U12>
         <PDBx:U13>0.07390</PDBx:U13>
         <PDBx:U22>0.17130</PDBx:U22>
         <PDBx:U23>0.04816</PDBx:U23>
         <PDBx:U33>0.27275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2895">
         <PDBx:U11>0.19608</PDBx:U11>
         <PDBx:U12>0.07372</PDBx:U12>
         <PDBx:U13>0.07735</PDBx:U13>
         <PDBx:U22>0.21360</PDBx:U22>
         <PDBx:U23>0.04621</PDBx:U23>
         <PDBx:U33>0.32385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2896">
         <PDBx:U11>0.19987</PDBx:U11>
         <PDBx:U12>0.07355</PDBx:U12>
         <PDBx:U13>0.07105</PDBx:U13>
         <PDBx:U22>0.22973</PDBx:U22>
         <PDBx:U23>0.04301</PDBx:U23>
         <PDBx:U33>0.32525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2897">
         <PDBx:U11>0.17504</PDBx:U11>
         <PDBx:U12>0.07637</PDBx:U12>
         <PDBx:U13>0.06936</PDBx:U13>
         <PDBx:U22>0.21410</PDBx:U22>
         <PDBx:U23>0.04501</PDBx:U23>
         <PDBx:U33>0.31105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2898">
         <PDBx:U11>0.23976</PDBx:U11>
         <PDBx:U12>0.07065</PDBx:U12>
         <PDBx:U13>0.08838</PDBx:U13>
         <PDBx:U22>0.24026</PDBx:U22>
         <PDBx:U23>0.03900</PDBx:U23>
         <PDBx:U33>0.36744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2899">
         <PDBx:U11>0.30143</PDBx:U11>
         <PDBx:U12>0.07102</PDBx:U12>
         <PDBx:U13>0.09599</PDBx:U13>
         <PDBx:U22>0.28778</PDBx:U22>
         <PDBx:U23>0.04161</PDBx:U23>
         <PDBx:U33>0.43451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2900">
         <PDBx:U11>0.42662</PDBx:U11>
         <PDBx:U12>0.06618</PDBx:U12>
         <PDBx:U13>0.10641</PDBx:U13>
         <PDBx:U22>0.39251</PDBx:U22>
         <PDBx:U23>0.03235</PDBx:U23>
         <PDBx:U33>0.55291</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2901">
         <PDBx:U11>0.20789</PDBx:U11>
         <PDBx:U12>0.06235</PDBx:U12>
         <PDBx:U13>0.10854</PDBx:U13>
         <PDBx:U22>0.16943</PDBx:U22>
         <PDBx:U23>0.02405</PDBx:U23>
         <PDBx:U33>0.32361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2902">
         <PDBx:U11>0.38710</PDBx:U11>
         <PDBx:U12>0.06582</PDBx:U12>
         <PDBx:U13>0.11292</PDBx:U13>
         <PDBx:U22>0.33951</PDBx:U22>
         <PDBx:U23>0.03323</PDBx:U23>
         <PDBx:U33>0.51727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>325</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2903">
         <PDBx:U11>0.14915</PDBx:U11>
         <PDBx:U12>0.07072</PDBx:U12>
         <PDBx:U13>0.06769</PDBx:U13>
         <PDBx:U22>0.17933</PDBx:U22>
         <PDBx:U23>0.03797</PDBx:U23>
         <PDBx:U33>0.26210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>326</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2904">
         <PDBx:U11>0.14453</PDBx:U11>
         <PDBx:U12>0.07040</PDBx:U12>
         <PDBx:U13>0.06317</PDBx:U13>
         <PDBx:U22>0.18429</PDBx:U22>
         <PDBx:U23>0.03491</PDBx:U23>
         <PDBx:U33>0.25600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>326</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2905">
         <PDBx:U11>0.13880</PDBx:U11>
         <PDBx:U12>0.07357</PDBx:U12>
         <PDBx:U13>0.05386</PDBx:U13>
         <PDBx:U22>0.19372</PDBx:U22>
         <PDBx:U23>0.04035</PDBx:U23>
         <PDBx:U33>0.25387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>326</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2906">
         <PDBx:U11>0.15217</PDBx:U11>
         <PDBx:U12>0.07445</PDBx:U12>
         <PDBx:U13>0.05115</PDBx:U13>
         <PDBx:U22>0.21695</PDBx:U22>
         <PDBx:U23>0.03962</PDBx:U23>
         <PDBx:U33>0.27403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>326</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2907">
         <PDBx:U11>0.15355</PDBx:U11>
         <PDBx:U12>0.06803</PDBx:U12>
         <PDBx:U13>0.06121</PDBx:U13>
         <PDBx:U22>0.18891</PDBx:U22>
         <PDBx:U23>0.02949</PDBx:U23>
         <PDBx:U33>0.25030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>326</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2908">
         <PDBx:U11>0.17019</PDBx:U11>
         <PDBx:U12>0.07508</PDBx:U12>
         <PDBx:U13>0.04972</PDBx:U13>
         <PDBx:U22>0.22722</PDBx:U22>
         <PDBx:U23>0.04576</PDBx:U23>
         <PDBx:U33>0.28099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2909">
         <PDBx:U11>0.14213</PDBx:U11>
         <PDBx:U12>0.07788</PDBx:U12>
         <PDBx:U13>0.04190</PDBx:U13>
         <PDBx:U22>0.21161</PDBx:U22>
         <PDBx:U23>0.05090</PDBx:U23>
         <PDBx:U33>0.25319</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2910">
         <PDBx:U11>0.19630</PDBx:U11>
         <PDBx:U12>0.08157</PDBx:U12>
         <PDBx:U13>0.04207</PDBx:U13>
         <PDBx:U22>0.27150</PDBx:U22>
         <PDBx:U23>0.05605</PDBx:U23>
         <PDBx:U33>0.32204</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2911">
         <PDBx:U11>0.22197</PDBx:U11>
         <PDBx:U12>0.08409</PDBx:U12>
         <PDBx:U13>0.03503</PDBx:U13>
         <PDBx:U22>0.30849</PDBx:U22>
         <PDBx:U23>0.05937</PDBx:U23>
         <PDBx:U33>0.34978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2912">
         <PDBx:U11>0.17649</PDBx:U11>
         <PDBx:U12>0.07861</PDBx:U12>
         <PDBx:U13>0.03985</PDBx:U13>
         <PDBx:U22>0.24683</PDBx:U22>
         <PDBx:U23>0.05597</PDBx:U23>
         <PDBx:U33>0.27914</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2913">
         <PDBx:U11>0.17971</PDBx:U11>
         <PDBx:U12>0.07631</PDBx:U12>
         <PDBx:U13>0.03684</PDBx:U13>
         <PDBx:U22>0.24929</PDBx:U22>
         <PDBx:U23>0.05052</PDBx:U23>
         <PDBx:U33>0.26913</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2914">
         <PDBx:U11>0.25682</PDBx:U11>
         <PDBx:U12>0.07669</PDBx:U12>
         <PDBx:U13>0.03844</PDBx:U13>
         <PDBx:U22>0.32629</PDBx:U22>
         <PDBx:U23>0.05484</PDBx:U23>
         <PDBx:U33>0.34231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2915">
         <PDBx:U11>0.16729</PDBx:U11>
         <PDBx:U12>0.07716</PDBx:U12>
         <PDBx:U13>0.02920</PDBx:U13>
         <PDBx:U22>0.24602</PDBx:U22>
         <PDBx:U23>0.04842</PDBx:U23>
         <PDBx:U33>0.24979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>327</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2916">
         <PDBx:U11>0.19551</PDBx:U11>
         <PDBx:U12>0.08241</PDBx:U12>
         <PDBx:U13>0.04973</PDBx:U13>
         <PDBx:U22>0.26295</PDBx:U22>
         <PDBx:U23>0.05650</PDBx:U23>
         <PDBx:U33>0.33178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2917">
         <PDBx:U11>0.19858</PDBx:U11>
         <PDBx:U12>0.08697</PDBx:U12>
         <PDBx:U13>0.05035</PDBx:U13>
         <PDBx:U22>0.27105</PDBx:U22>
         <PDBx:U23>0.06057</PDBx:U23>
         <PDBx:U33>0.35138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2918">
         <PDBx:U11>0.25166</PDBx:U11>
         <PDBx:U12>0.08650</PDBx:U12>
         <PDBx:U13>0.05320</PDBx:U13>
         <PDBx:U22>0.32904</PDBx:U22>
         <PDBx:U23>0.05424</PDBx:U23>
         <PDBx:U33>0.41589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2919">
         <PDBx:U11>0.22570</PDBx:U11>
         <PDBx:U12>0.09069</PDBx:U12>
         <PDBx:U13>0.05462</PDBx:U13>
         <PDBx:U22>0.30817</PDBx:U22>
         <PDBx:U23>0.05625</PDBx:U23>
         <PDBx:U33>0.40652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2920">
         <PDBx:U11>0.17149</PDBx:U11>
         <PDBx:U12>0.08917</PDBx:U12>
         <PDBx:U13>0.05788</PDBx:U13>
         <PDBx:U22>0.23219</PDBx:U22>
         <PDBx:U23>0.06519</PDBx:U23>
         <PDBx:U33>0.33080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2921">
         <PDBx:U11>0.24862</PDBx:U11>
         <PDBx:U12>0.09020</PDBx:U12>
         <PDBx:U13>0.05640</PDBx:U13>
         <PDBx:U22>0.30667</PDBx:U22>
         <PDBx:U23>0.07341</PDBx:U23>
         <PDBx:U33>0.40091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2922">
         <PDBx:U11>0.36945</PDBx:U11>
         <PDBx:U12>0.09261</PDBx:U12>
         <PDBx:U13>0.06445</PDBx:U13>
         <PDBx:U22>0.41495</PDBx:U22>
         <PDBx:U23>0.07880</PDBx:U23>
         <PDBx:U33>0.53044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2923">
         <PDBx:U11>0.54272</PDBx:U11>
         <PDBx:U12>0.09112</PDBx:U12>
         <PDBx:U13>0.06621</PDBx:U13>
         <PDBx:U22>0.58316</PDBx:U22>
         <PDBx:U23>0.08484</PDBx:U23>
         <PDBx:U33>0.69524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2924">
         <PDBx:U11>0.72568</PDBx:U11>
         <PDBx:U12>0.09528</PDBx:U12>
         <PDBx:U13>0.07076</PDBx:U13>
         <PDBx:U22>0.75870</PDBx:U22>
         <PDBx:U23>0.09501</PDBx:U23>
         <PDBx:U33>0.88744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>328</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2925">
         <PDBx:U11>0.20075</PDBx:U11>
         <PDBx:U12>0.08191</PDBx:U12>
         <PDBx:U13>0.05455</PDBx:U13>
         <PDBx:U22>0.27751</PDBx:U22>
         <PDBx:U23>0.04704</PDBx:U23>
         <PDBx:U33>0.35776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2926">
         <PDBx:U11>0.22242</PDBx:U11>
         <PDBx:U12>0.08048</PDBx:U12>
         <PDBx:U13>0.05999</PDBx:U13>
         <PDBx:U22>0.30350</PDBx:U22>
         <PDBx:U23>0.04137</PDBx:U23>
         <PDBx:U33>0.39040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2927">
         <PDBx:U11>0.21991</PDBx:U11>
         <PDBx:U12>0.08305</PDBx:U12>
         <PDBx:U13>0.05248</PDBx:U13>
         <PDBx:U22>0.32030</PDBx:U22>
         <PDBx:U23>0.04293</PDBx:U23>
         <PDBx:U33>0.40120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2928">
         <PDBx:U11>0.18426</PDBx:U11>
         <PDBx:U12>0.08400</PDBx:U12>
         <PDBx:U13>0.04246</PDBx:U13>
         <PDBx:U22>0.29257</PDBx:U22>
         <PDBx:U23>0.04600</PDBx:U23>
         <PDBx:U33>0.35963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2929">
         <PDBx:U11>0.24167</PDBx:U11>
         <PDBx:U12>0.07475</PDBx:U12>
         <PDBx:U13>0.06415</PDBx:U13>
         <PDBx:U22>0.31541</PDBx:U22>
         <PDBx:U23>0.03450</PDBx:U23>
         <PDBx:U33>0.39676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2930">
         <PDBx:U11>0.20799</PDBx:U11>
         <PDBx:U12>0.07167</PDBx:U12>
         <PDBx:U13>0.07350</PDBx:U13>
         <PDBx:U22>0.28255</PDBx:U22>
         <PDBx:U23>0.02864</PDBx:U23>
         <PDBx:U33>0.37200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2931">
         <PDBx:U11>0.21186</PDBx:U11>
         <PDBx:U12>0.07060</PDBx:U12>
         <PDBx:U13>0.07157</PDBx:U13>
         <PDBx:U22>0.30178</PDBx:U22>
         <PDBx:U23>0.02717</PDBx:U23>
         <PDBx:U33>0.38636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2932">
         <PDBx:U11>0.18501</PDBx:U11>
         <PDBx:U12>0.06851</PDBx:U12>
         <PDBx:U13>0.08589</PDBx:U13>
         <PDBx:U22>0.24658</PDBx:U22>
         <PDBx:U23>0.02357</PDBx:U23>
         <PDBx:U33>0.34854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2933">
         <PDBx:U11>0.20084</PDBx:U11>
         <PDBx:U12>0.06661</PDBx:U12>
         <PDBx:U13>0.08304</PDBx:U13>
         <PDBx:U22>0.28824</PDBx:U22>
         <PDBx:U23>0.02180</PDBx:U23>
         <PDBx:U33>0.38202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2934">
         <PDBx:U11>0.21886</PDBx:U11>
         <PDBx:U12>0.06536</PDBx:U12>
         <PDBx:U13>0.09194</PDBx:U13>
         <PDBx:U22>0.28822</PDBx:U22>
         <PDBx:U23>0.01927</PDBx:U23>
         <PDBx:U33>0.39215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>329</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2935">
         <PDBx:U11>0.22327</PDBx:U11>
         <PDBx:U12>0.08401</PDBx:U12>
         <PDBx:U13>0.05742</PDBx:U13>
         <PDBx:U22>0.33207</PDBx:U22>
         <PDBx:U23>0.04045</PDBx:U23>
         <PDBx:U33>0.42320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>330</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2936">
         <PDBx:U11>0.24934</PDBx:U11>
         <PDBx:U12>0.08638</PDBx:U12>
         <PDBx:U13>0.04974</PDBx:U13>
         <PDBx:U22>0.37904</PDBx:U22>
         <PDBx:U23>0.04182</PDBx:U23>
         <PDBx:U33>0.46546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>330</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2937">
         <PDBx:U11>0.22996</PDBx:U11>
         <PDBx:U12>0.08226</PDBx:U12>
         <PDBx:U13>0.04334</PDBx:U13>
         <PDBx:U22>0.36867</PDBx:U22>
         <PDBx:U23>0.03953</PDBx:U23>
         <PDBx:U33>0.43979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>330</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2938">
         <PDBx:U11>0.20356</PDBx:U11>
         <PDBx:U12>0.08428</PDBx:U12>
         <PDBx:U13>0.03320</PDBx:U13>
         <PDBx:U22>0.35810</PDBx:U22>
         <PDBx:U23>0.04216</PDBx:U23>
         <PDBx:U33>0.42176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>330</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2939">
         <PDBx:U11>0.30733</PDBx:U11>
         <PDBx:U12>0.08655</PDBx:U12>
         <PDBx:U13>0.05948</PDBx:U13>
         <PDBx:U22>0.44344</PDBx:U22>
         <PDBx:U23>0.03775</PDBx:U23>
         <PDBx:U33>0.54434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>330</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2940">
         <PDBx:U11>0.33975</PDBx:U11>
         <PDBx:U12>0.08804</PDBx:U12>
         <PDBx:U13>0.06927</PDBx:U13>
         <PDBx:U22>0.45819</PDBx:U22>
         <PDBx:U23>0.03745</PDBx:U23>
         <PDBx:U33>0.57382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>330</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2941">
         <PDBx:U11>0.26045</PDBx:U11>
         <PDBx:U12>0.08392</PDBx:U12>
         <PDBx:U13>0.06992</PDBx:U13>
         <PDBx:U22>0.36084</PDBx:U22>
         <PDBx:U23>0.03700</PDBx:U23>
         <PDBx:U33>0.46964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>330</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2942">
         <PDBx:U11>0.17786</PDBx:U11>
         <PDBx:U12>0.07685</PDBx:U12>
         <PDBx:U13>0.04860</PDBx:U13>
         <PDBx:U22>0.30661</PDBx:U22>
         <PDBx:U23>0.03495</PDBx:U23>
         <PDBx:U33>0.37354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2943">
         <PDBx:U11>0.20786</PDBx:U11>
         <PDBx:U12>0.07380</PDBx:U12>
         <PDBx:U13>0.04274</PDBx:U13>
         <PDBx:U22>0.34381</PDBx:U22>
         <PDBx:U23>0.03354</PDBx:U23>
         <PDBx:U33>0.39759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2944">
         <PDBx:U11>0.18014</PDBx:U11>
         <PDBx:U12>0.07726</PDBx:U12>
         <PDBx:U13>0.02909</PDBx:U13>
         <PDBx:U22>0.32030</PDBx:U22>
         <PDBx:U23>0.03838</PDBx:U23>
         <PDBx:U33>0.35984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2945">
         <PDBx:U11>0.21486</PDBx:U11>
         <PDBx:U12>0.07657</PDBx:U12>
         <PDBx:U13>0.02080</PDBx:U13>
         <PDBx:U22>0.36734</PDBx:U22>
         <PDBx:U23>0.03874</PDBx:U23>
         <PDBx:U33>0.39650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2946">
         <PDBx:U11>0.15488</PDBx:U11>
         <PDBx:U12>0.06928</PDBx:U12>
         <PDBx:U13>0.05029</PDBx:U13>
         <PDBx:U22>0.27548</PDBx:U22>
         <PDBx:U23>0.02912</PDBx:U23>
         <PDBx:U33>0.32767</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2947">
         <PDBx:U11>0.16336</PDBx:U11>
         <PDBx:U12>0.06743</PDBx:U12>
         <PDBx:U13>0.04522</PDBx:U13>
         <PDBx:U22>0.28943</PDBx:U22>
         <PDBx:U23>0.02837</PDBx:U23>
         <PDBx:U33>0.32943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2948">
         <PDBx:U11>0.20240</PDBx:U11>
         <PDBx:U12>0.06410</PDBx:U12>
         <PDBx:U13>0.04436</PDBx:U13>
         <PDBx:U22>0.34579</PDBx:U22>
         <PDBx:U23>0.02784</PDBx:U23>
         <PDBx:U33>0.38544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2949">
         <PDBx:U11>0.16856</PDBx:U11>
         <PDBx:U12>0.06916</PDBx:U12>
         <PDBx:U13>0.04100</PDBx:U13>
         <PDBx:U22>0.28336</PDBx:U22>
         <PDBx:U23>0.02839</PDBx:U23>
         <PDBx:U33>0.31233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2950">
         <PDBx:U11>0.21635</PDBx:U11>
         <PDBx:U12>0.05960</PDBx:U12>
         <PDBx:U13>0.03714</PDBx:U13>
         <PDBx:U22>0.35935</PDBx:U22>
         <PDBx:U23>0.02584</PDBx:U23>
         <PDBx:U33>0.38618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2951">
         <PDBx:U11>0.18627</PDBx:U11>
         <PDBx:U12>0.06745</PDBx:U12>
         <PDBx:U13>0.03435</PDBx:U13>
         <PDBx:U22>0.30208</PDBx:U22>
         <PDBx:U23>0.02657</PDBx:U23>
         <PDBx:U33>0.31786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2952">
         <PDBx:U11>0.24044</PDBx:U11>
         <PDBx:U12>0.06033</PDBx:U12>
         <PDBx:U13>0.03100</PDBx:U13>
         <PDBx:U22>0.36532</PDBx:U22>
         <PDBx:U23>0.02390</PDBx:U23>
         <PDBx:U33>0.37950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>331</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2953">
         <PDBx:U11>0.15703</PDBx:U11>
         <PDBx:U12>0.08024</PDBx:U12>
         <PDBx:U13>0.02724</PDBx:U13>
         <PDBx:U22>0.28715</PDBx:U22>
         <PDBx:U23>0.04232</PDBx:U23>
         <PDBx:U33>0.32584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2954">
         <PDBx:U11>0.17494</PDBx:U11>
         <PDBx:U12>0.08256</PDBx:U12>
         <PDBx:U13>0.01700</PDBx:U13>
         <PDBx:U22>0.30688</PDBx:U22>
         <PDBx:U23>0.04702</PDBx:U23>
         <PDBx:U33>0.33149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2955">
         <PDBx:U11>0.19277</PDBx:U11>
         <PDBx:U12>0.08717</PDBx:U12>
         <PDBx:U13>0.00965</PDBx:U13>
         <PDBx:U22>0.33574</PDBx:U22>
         <PDBx:U23>0.05325</PDBx:U23>
         <PDBx:U33>0.36057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2956">
         <PDBx:U11>0.24006</PDBx:U11>
         <PDBx:U12>0.08900</PDBx:U12>
         <PDBx:U13>0.00184</PDBx:U13>
         <PDBx:U22>0.38476</PDBx:U22>
         <PDBx:U23>0.05790</PDBx:U23>
         <PDBx:U33>0.39698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2957">
         <PDBx:U11>0.18095</PDBx:U11>
         <PDBx:U12>0.08230</PDBx:U12>
         <PDBx:U13>0.02012</PDBx:U13>
         <PDBx:U22>0.29789</PDBx:U22>
         <PDBx:U23>0.04855</PDBx:U23>
         <PDBx:U33>0.32017</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2958">
         <PDBx:U11>0.14634</PDBx:U11>
         <PDBx:U12>0.07869</PDBx:U12>
         <PDBx:U13>0.02444</PDBx:U13>
         <PDBx:U22>0.25303</PDBx:U22>
         <PDBx:U23>0.04280</PDBx:U23>
         <PDBx:U33>0.27274</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2959">
         <PDBx:U11>0.11805</PDBx:U11>
         <PDBx:U12>0.07772</PDBx:U12>
         <PDBx:U13>0.01932</PDBx:U13>
         <PDBx:U22>0.22830</PDBx:U22>
         <PDBx:U23>0.03972</PDBx:U23>
         <PDBx:U33>0.23554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2960">
         <PDBx:U11>0.20920</PDBx:U11>
         <PDBx:U12>0.07689</PDBx:U12>
         <PDBx:U13>0.03295</PDBx:U13>
         <PDBx:U22>0.30246</PDBx:U22>
         <PDBx:U23>0.04074</PDBx:U23>
         <PDBx:U33>0.33210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2961">
         <PDBx:U11>0.14467</PDBx:U11>
         <PDBx:U12>0.07596</PDBx:U12>
         <PDBx:U13>0.02248</PDBx:U13>
         <PDBx:U22>0.24504</PDBx:U22>
         <PDBx:U23>0.03501</PDBx:U23>
         <PDBx:U33>0.24985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2962">
         <PDBx:U11>0.15537</PDBx:U11>
         <PDBx:U12>0.07425</PDBx:U12>
         <PDBx:U13>0.03590</PDBx:U13>
         <PDBx:U22>0.23907</PDBx:U22>
         <PDBx:U23>0.03572</PDBx:U23>
         <PDBx:U33>0.26606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2963">
         <PDBx:U11>0.14087</PDBx:U11>
         <PDBx:U12>0.07422</PDBx:U12>
         <PDBx:U13>0.03066</PDBx:U13>
         <PDBx:U22>0.22798</PDBx:U22>
         <PDBx:U23>0.03298</PDBx:U23>
         <PDBx:U33>0.24272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>332</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2964">
         <PDBx:U11>0.19473</PDBx:U11>
         <PDBx:U12>0.08949</PDBx:U12>
         <PDBx:U13>0.01204</PDBx:U13>
         <PDBx:U22>0.34566</PDBx:U22>
         <PDBx:U23>0.05356</PDBx:U23>
         <PDBx:U33>0.38377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2965">
         <PDBx:U11>0.27220</PDBx:U11>
         <PDBx:U12>0.09516</PDBx:U12>
         <PDBx:U13>0.00401</PDBx:U13>
         <PDBx:U22>0.43338</PDBx:U22>
         <PDBx:U23>0.05999</PDBx:U23>
         <PDBx:U33>0.47270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2966">
         <PDBx:U11>0.31053</PDBx:U11>
         <PDBx:U12>0.09508</PDBx:U12>
         <PDBx:U13>-0.00933</PDBx:U13>
         <PDBx:U22>0.48557</PDBx:U22>
         <PDBx:U23>0.06150</PDBx:U23>
         <PDBx:U33>0.50943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2967">
         <PDBx:U11>0.28171</PDBx:U11>
         <PDBx:U12>0.09900</PDBx:U12>
         <PDBx:U13>-0.01827</PDBx:U13>
         <PDBx:U22>0.45989</PDBx:U22>
         <PDBx:U23>0.06819</PDBx:U23>
         <PDBx:U33>0.47659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2968">
         <PDBx:U11>0.18565</PDBx:U11>
         <PDBx:U12>0.09827</PDBx:U12>
         <PDBx:U13>0.00878</PDBx:U13>
         <PDBx:U22>0.35518</PDBx:U22>
         <PDBx:U23>0.05883</PDBx:U23>
         <PDBx:U33>0.41159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2969">
         <PDBx:U11>0.32943</PDBx:U11>
         <PDBx:U12>0.10136</PDBx:U12>
         <PDBx:U13>0.01842</PDBx:U13>
         <PDBx:U22>0.48502</PDBx:U22>
         <PDBx:U23>0.06104</PDBx:U23>
         <PDBx:U33>0.55712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2970">
         <PDBx:U11>0.36660</PDBx:U11>
         <PDBx:U12>0.09986</PDBx:U12>
         <PDBx:U13>0.02202</PDBx:U13>
         <PDBx:U22>0.50659</PDBx:U22>
         <PDBx:U23>0.06294</PDBx:U23>
         <PDBx:U33>0.57690</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2971">
         <PDBx:U11>0.43636</PDBx:U11>
         <PDBx:U12>0.10551</PDBx:U12>
         <PDBx:U13>0.02229</PDBx:U13>
         <PDBx:U22>0.59742</PDBx:U22>
         <PDBx:U23>0.06101</PDBx:U23>
         <PDBx:U33>0.68419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>333</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2972">
         <PDBx:U11>0.28399</PDBx:U11>
         <PDBx:U12>0.09041</PDBx:U12>
         <PDBx:U13>-0.01107</PDBx:U13>
         <PDBx:U22>0.46714</PDBx:U22>
         <PDBx:U23>0.05592</PDBx:U23>
         <PDBx:U33>0.48522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>334</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2973">
         <PDBx:U11>0.31557</PDBx:U11>
         <PDBx:U12>0.08943</PDBx:U12>
         <PDBx:U13>-0.02456</PDBx:U13>
         <PDBx:U22>0.51135</PDBx:U22>
         <PDBx:U23>0.05696</PDBx:U23>
         <PDBx:U33>0.51414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>334</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>334</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>334</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>334</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>334</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>334</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.04919</PDBx:U23>
         <PDBx:U33>0.33408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>335</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>336</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U33>0.64281</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>336</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>336</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.08392</PDBx:U23>
         <PDBx:U33>0.95095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>336</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U33>0.94468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>336</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.08753</PDBx:U23>
         <PDBx:U33>0.98731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>336</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>0.11042</PDBx:U12>
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         <PDBx:U22>0.97492</PDBx:U22>
         <PDBx:U23>0.10133</PDBx:U23>
         <PDBx:U33>0.94379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>0.11337</PDBx:U12>
         <PDBx:U13>-0.05094</PDBx:U13>
         <PDBx:U22>1.10862</PDBx:U22>
         <PDBx:U23>0.10871</PDBx:U23>
         <PDBx:U33>1.06101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.11648</PDBx:U12>
         <PDBx:U13>-0.06324</PDBx:U13>
         <PDBx:U22>1.17629</PDBx:U22>
         <PDBx:U23>0.10883</PDBx:U23>
         <PDBx:U33>1.13589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>1.16797</PDBx:U22>
         <PDBx:U23>0.10867</PDBx:U23>
         <PDBx:U33>1.14824</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U12>0.11760</PDBx:U12>
         <PDBx:U13>-0.04851</PDBx:U13>
         <PDBx:U22>1.10099</PDBx:U22>
         <PDBx:U23>0.12052</PDBx:U23>
         <PDBx:U33>1.05166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.11958</PDBx:U12>
         <PDBx:U13>-0.06039</PDBx:U13>
         <PDBx:U22>1.11988</PDBx:U22>
         <PDBx:U23>0.12850</PDBx:U23>
         <PDBx:U33>1.04804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.14179</PDBx:U23>
         <PDBx:U33>1.06125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.14996</PDBx:U23>
         <PDBx:U33>1.06319</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.16420</PDBx:U23>
         <PDBx:U33>1.08748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>337</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.07664</PDBx:U13>
         <PDBx:U22>1.23800</PDBx:U22>
         <PDBx:U23>0.10863</PDBx:U23>
         <PDBx:U33>1.17968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>338</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3007">
         <PDBx:U11>1.11007</PDBx:U11>
         <PDBx:U12>0.11818</PDBx:U12>
         <PDBx:U13>-0.09065</PDBx:U13>
         <PDBx:U22>1.31683</PDBx:U22>
         <PDBx:U23>0.10904</PDBx:U23>
         <PDBx:U33>1.26264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>338</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3008">
         <PDBx:U11>1.08920</PDBx:U11>
         <PDBx:U12>0.12643</PDBx:U12>
         <PDBx:U13>-0.09554</PDBx:U13>
         <PDBx:U22>1.29488</PDBx:U22>
         <PDBx:U23>0.11941</PDBx:U23>
         <PDBx:U33>1.25022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>338</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3009">
         <PDBx:U11>1.15163</PDBx:U11>
         <PDBx:U12>0.12879</PDBx:U12>
         <PDBx:U13>-0.09577</PDBx:U13>
         <PDBx:U22>1.34781</PDBx:U22>
         <PDBx:U23>0.12873</PDBx:U23>
         <PDBx:U33>1.29435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>338</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3010">
         <PDBx:U11>1.17334</PDBx:U11>
         <PDBx:U12>0.11463</PDBx:U12>
         <PDBx:U13>-0.10536</PDBx:U13>
         <PDBx:U22>1.38679</PDBx:U22>
         <PDBx:U23>0.10763</PDBx:U23>
         <PDBx:U33>1.30900</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>338</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3011">
         <PDBx:U11>1.18363</PDBx:U11>
         <PDBx:U12>0.11501</PDBx:U12>
         <PDBx:U13>-0.10811</PDBx:U13>
         <PDBx:U22>1.38868</PDBx:U22>
         <PDBx:U23>0.11474</PDBx:U23>
         <PDBx:U33>1.28977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>338</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3012">
         <PDBx:U11>0.93252</PDBx:U11>
         <PDBx:U12>0.13118</PDBx:U12>
         <PDBx:U13>-0.09914</PDBx:U13>
         <PDBx:U22>1.14874</PDBx:U22>
         <PDBx:U23>0.11790</PDBx:U23>
         <PDBx:U33>1.12186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3013">
         <PDBx:U11>0.78971</PDBx:U11>
         <PDBx:U12>0.14050</PDBx:U12>
         <PDBx:U13>-0.10276</PDBx:U13>
         <PDBx:U22>1.00499</PDBx:U22>
         <PDBx:U23>0.12673</PDBx:U23>
         <PDBx:U33>0.99183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3014">
         <PDBx:U11>0.80186</PDBx:U11>
         <PDBx:U12>0.14497</PDBx:U12>
         <PDBx:U13>-0.12156</PDBx:U13>
         <PDBx:U22>1.02050</PDBx:U22>
         <PDBx:U23>0.13564</PDBx:U23>
         <PDBx:U33>0.99195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3015">
         <PDBx:U11>0.80874</PDBx:U11>
         <PDBx:U12>0.14035</PDBx:U12>
         <PDBx:U13>-0.13203</PDBx:U13>
         <PDBx:U22>1.03145</PDBx:U22>
         <PDBx:U23>0.13397</PDBx:U23>
         <PDBx:U33>0.98148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3016">
         <PDBx:U11>0.65955</PDBx:U11>
         <PDBx:U12>0.14484</PDBx:U12>
         <PDBx:U13>-0.09999</PDBx:U13>
         <PDBx:U22>0.88776</PDBx:U22>
         <PDBx:U23>0.12102</PDBx:U23>
         <PDBx:U33>0.89706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3017">
         <PDBx:U11>0.66044</PDBx:U11>
         <PDBx:U12>0.15319</PDBx:U12>
         <PDBx:U13>-0.09284</PDBx:U13>
         <PDBx:U22>0.87972</PDBx:U22>
         <PDBx:U23>0.12759</PDBx:U23>
         <PDBx:U33>0.91051</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3018">
         <PDBx:U11>0.57763</PDBx:U11>
         <PDBx:U12>0.14750</PDBx:U12>
         <PDBx:U13>-0.11690</PDBx:U13>
         <PDBx:U22>0.82723</PDBx:U22>
         <PDBx:U23>0.11908</PDBx:U23>
         <PDBx:U33>0.83106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3019">
         <PDBx:U11>0.70190</PDBx:U11>
         <PDBx:U12>0.16240</PDBx:U12>
         <PDBx:U13>-0.10612</PDBx:U13>
         <PDBx:U22>0.91894</PDBx:U22>
         <PDBx:U23>0.13997</PDBx:U23>
         <PDBx:U33>0.94879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>339</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
   </PDBx:atom_site_anisotropCategory>
   <PDBx:atom_sitesCategory>
      <PDBx:atom_sites entry_id="6TW2">
         <PDBx:fract_transf_matrix11>0.010995</PDBx:fract_transf_matrix11>
         <PDBx:fract_transf_matrix12>0.000000</PDBx:fract_transf_matrix12>
         <PDBx:fract_transf_matrix13>0.005888</PDBx:fract_transf_matrix13>
         <PDBx:fract_transf_matrix21>0.000000</PDBx:fract_transf_matrix21>
         <PDBx:fract_transf_matrix22>0.015599</PDBx:fract_transf_matrix22>
         <PDBx:fract_transf_matrix23>0.000000</PDBx:fract_transf_matrix23>
         <PDBx:fract_transf_matrix31>0.000000</PDBx:fract_transf_matrix31>
         <PDBx:fract_transf_matrix32>0.000000</PDBx:fract_transf_matrix32>
         <PDBx:fract_transf_matrix33>0.014378</PDBx:fract_transf_matrix33>
         <PDBx:fract_transf_vector1>0.00000</PDBx:fract_transf_vector1>
         <PDBx:fract_transf_vector2>0.00000</PDBx:fract_transf_vector2>
         <PDBx:fract_transf_vector3>0.00000</PDBx:fract_transf_vector3>
      </PDBx:atom_sites>
   </PDBx:atom_sitesCategory>
   <PDBx:atom_typeCategory>
      <PDBx:atom_type symbol="C">
         <PDBx:scat_Cromer_Mann_a1>3.54356</PDBx:scat_Cromer_Mann_a1>
         <PDBx:scat_Cromer_Mann_a2>2.42580</PDBx:scat_Cromer_Mann_a2>
         <PDBx:scat_Cromer_Mann_b1>25.62398</PDBx:scat_Cromer_Mann_b1>
         <PDBx:scat_Cromer_Mann_b2>1.50364</PDBx:scat_Cromer_Mann_b2>
         <PDBx:scat_Cromer_Mann_c>0.0</PDBx:scat_Cromer_Mann_c>
         <PDBx:scat_source>2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.</PDBx:scat_source>
      </PDBx:atom_type>
      <PDBx:atom_type symbol="CL">
         <PDBx:scat_Cromer_Mann_a1>9.50761</PDBx:scat_Cromer_Mann_a1>
         <PDBx:scat_Cromer_Mann_a2>7.44341</PDBx:scat_Cromer_Mann_a2>
         <PDBx:scat_Cromer_Mann_b1>1.04373</PDBx:scat_Cromer_Mann_b1>
         <PDBx:scat_Cromer_Mann_b2>23.83732</PDBx:scat_Cromer_Mann_b2>
         <PDBx:scat_Cromer_Mann_c>0.0</PDBx:scat_Cromer_Mann_c>
         <PDBx:scat_source>2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.</PDBx:scat_source>
      </PDBx:atom_type>
      <PDBx:atom_type symbol="N">
         <PDBx:scat_Cromer_Mann_a1>4.01032</PDBx:scat_Cromer_Mann_a1>
         <PDBx:scat_Cromer_Mann_a2>2.96436</PDBx:scat_Cromer_Mann_a2>
         <PDBx:scat_Cromer_Mann_b1>19.97189</PDBx:scat_Cromer_Mann_b1>
         <PDBx:scat_Cromer_Mann_b2>1.75589</PDBx:scat_Cromer_Mann_b2>
         <PDBx:scat_Cromer_Mann_c>0.0</PDBx:scat_Cromer_Mann_c>
         <PDBx:scat_source>2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.</PDBx:scat_source>
      </PDBx:atom_type>
      <PDBx:atom_type symbol="O">
         <PDBx:scat_Cromer_Mann_a1>4.49882</PDBx:scat_Cromer_Mann_a1>
         <PDBx:scat_Cromer_Mann_a2>3.47563</PDBx:scat_Cromer_Mann_a2>
         <PDBx:scat_Cromer_Mann_b1>15.80542</PDBx:scat_Cromer_Mann_b1>
         <PDBx:scat_Cromer_Mann_b2>1.70748</PDBx:scat_Cromer_Mann_b2>
         <PDBx:scat_Cromer_Mann_c>0.0</PDBx:scat_Cromer_Mann_c>
         <PDBx:scat_source>2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.</PDBx:scat_source>
      </PDBx:atom_type>
      <PDBx:atom_type symbol="P">
         <PDBx:scat_Cromer_Mann_a1>9.51135</PDBx:scat_Cromer_Mann_a1>
         <PDBx:scat_Cromer_Mann_a2>5.44231</PDBx:scat_Cromer_Mann_a2>
         <PDBx:scat_Cromer_Mann_b1>1.42069</PDBx:scat_Cromer_Mann_b1>
         <PDBx:scat_Cromer_Mann_b2>35.72801</PDBx:scat_Cromer_Mann_b2>
         <PDBx:scat_Cromer_Mann_c>0.0</PDBx:scat_Cromer_Mann_c>
         <PDBx:scat_source>2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.</PDBx:scat_source>
      </PDBx:atom_type>
      <PDBx:atom_type symbol="S">
         <PDBx:scat_Cromer_Mann_a1>9.55732</PDBx:scat_Cromer_Mann_a1>
         <PDBx:scat_Cromer_Mann_a2>6.39887</PDBx:scat_Cromer_Mann_a2>
         <PDBx:scat_Cromer_Mann_b1>1.23737</PDBx:scat_Cromer_Mann_b1>
         <PDBx:scat_Cromer_Mann_b2>29.19336</PDBx:scat_Cromer_Mann_b2>
         <PDBx:scat_Cromer_Mann_c>0.0</PDBx:scat_Cromer_Mann_c>
         <PDBx:scat_source>2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.</PDBx:scat_source>
      </PDBx:atom_type>
   </PDBx:atom_typeCategory>
   <PDBx:audit_authorCategory>
      <PDBx:audit_author pdbx_ordinal="1">
         <PDBx:identifier_ORCID>0000-0001-7928-4488</PDBx:identifier_ORCID>
         <PDBx:name>Loll, B.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="2">
         <PDBx:name>Haltenhof, T.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="3">
         <PDBx:name>Heyd, F.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="4">
         <PDBx:identifier_ORCID>0000-0002-2811-5307</PDBx:identifier_ORCID>
         <PDBx:name>Wahl, M.C.</PDBx:name>
      </PDBx:audit_author>
   </PDBx:audit_authorCategory>
   <PDBx:audit_conformCategory>
      <PDBx:audit_conform dict_name="mmcif_pdbx.dic" dict_version="5.324">
         <PDBx:dict_location>http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic</PDBx:dict_location>
      </PDBx:audit_conform>
   </PDBx:audit_conformCategory>
   <PDBx:cellCategory>
      <PDBx:cell entry_id="6TW2">
         <PDBx:Z_PDB>4</PDBx:Z_PDB>
         <PDBx:angle_alpha>90.000</PDBx:angle_alpha>
         <PDBx:angle_beta>118.170</PDBx:angle_beta>
         <PDBx:angle_gamma>90.000</PDBx:angle_gamma>
         <PDBx:length_a>90.950</PDBx:length_a>
         <PDBx:length_b>64.108</PDBx:length_b>
         <PDBx:length_c>78.894</PDBx:length_c>
         <PDBx:volume>405514.353</PDBx:volume>
      </PDBx:cell>
   </PDBx:cellCategory>
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      <PDBx:chem_comp id="ALA">
         <PDBx:formula>C3 H7 N O2</PDBx:formula>
         <PDBx:formula_weight>89.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ARG">
         <PDBx:formula>C6 H15 N4 O2 1</PDBx:formula>
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         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ARGININE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASN">
         <PDBx:formula>C4 H8 N2 O3</PDBx:formula>
         <PDBx:formula_weight>132.118</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARAGINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASP">
         <PDBx:formula>C4 H7 N O4</PDBx:formula>
         <PDBx:formula_weight>133.103</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARTIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="CYS">
         <PDBx:formula>C3 H7 N O2 S</PDBx:formula>
         <PDBx:formula_weight>121.158</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>CYSTEINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLN">
         <PDBx:formula>C5 H10 N2 O3</PDBx:formula>
         <PDBx:formula_weight>146.144</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLU">
         <PDBx:formula>C5 H9 N O4</PDBx:formula>
         <PDBx:formula_weight>147.129</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLY">
         <PDBx:formula>C2 H5 N O2</PDBx:formula>
         <PDBx:formula_weight>75.067</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLYCINE</PDBx:name>
         <PDBx:type>peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HIS">
         <PDBx:formula>C6 H10 N3 O2 1</PDBx:formula>
         <PDBx:formula_weight>156.162</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>HISTIDINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HOH">
         <PDBx:formula>H2 O</PDBx:formula>
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>WATER</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ILE">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ISOLEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LEU">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LYS">
         <PDBx:formula>C6 H15 N2 O2 1</PDBx:formula>
         <PDBx:formula_weight>147.195</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LYSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="MET">
         <PDBx:formula>C5 H11 N O2 S</PDBx:formula>
         <PDBx:formula_weight>149.211</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>METHIONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PHE">
         <PDBx:formula>C9 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>165.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PHENYLALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PRO">
         <PDBx:formula>C5 H9 N O2</PDBx:formula>
         <PDBx:formula_weight>115.130</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PROLINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="SEP">
         <PDBx:formula>C3 H8 N O6 P</PDBx:formula>
         <PDBx:formula_weight>185.072</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>n</PDBx:mon_nstd_flag>
         <PDBx:name>PHOSPHOSERINE</PDBx:name>
         <PDBx:pdbx_synonyms>PHOSPHONOSERINE</PDBx:pdbx_synonyms>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="SER">
         <PDBx:formula>C3 H7 N O3</PDBx:formula>
         <PDBx:formula_weight>105.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>SERINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="THR">
         <PDBx:formula>C4 H9 N O3</PDBx:formula>
         <PDBx:formula_weight>119.119</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>THREONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TPO">
         <PDBx:formula>C4 H10 N O6 P</PDBx:formula>
         <PDBx:formula_weight>199.099</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>n</PDBx:mon_nstd_flag>
         <PDBx:name>PHOSPHOTHREONINE</PDBx:name>
         <PDBx:pdbx_synonyms>PHOSPHONOTHREONINE</PDBx:pdbx_synonyms>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TRP">
         <PDBx:formula>C11 H12 N2 O2</PDBx:formula>
         <PDBx:formula_weight>204.225</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TRYPTOPHAN</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TYR">
         <PDBx:formula>C9 H11 N O3</PDBx:formula>
         <PDBx:formula_weight>181.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TYROSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="V25">
         <PDBx:formula>C15 H13 Cl2 N3 O2</PDBx:formula>
         <PDBx:formula_weight>338.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="VAL">
         <PDBx:formula>C5 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>117.146</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>VALINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
   </PDBx:chem_compCategory>
   <PDBx:citationCategory>
      <PDBx:citation id="primary">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>Mol.Cell</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>MOCEFL</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>2168</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>1097-2765</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>78</PDBx:journal_volume>
         <PDBx:page_first>57</PDBx:page_first>
         <PDBx:page_last>69.e4</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1016/j.molcel.2020.01.028</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>32059760</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression.</PDBx:title>
         <PDBx:year>2020</PDBx:year>
      </PDBx:citation>
   </PDBx:citationCategory>
   <PDBx:citation_authorCategory>
      <PDBx:citation_author citation_id="primary" name="Haltenhof, T." ordinal="1">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Kotte, A." ordinal="2">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="De Bortoli, F." ordinal="3">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Schiefer, S." ordinal="4">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Meinke, S." ordinal="5">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Emmerichs, A.K." ordinal="6">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Petermann, K.K." ordinal="7">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Timmermann, B." ordinal="8">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Imhof, P." ordinal="9">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Franz, A." ordinal="10">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Loll, B." ordinal="11">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Wahl, M.C." ordinal="12">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Preussner, M." ordinal="13">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Heyd, F." ordinal="14">
      </PDBx:citation_author>
   </PDBx:citation_authorCategory>
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      <PDBx:database_2 database_code="6TW2" database_id="PDB"></PDBx:database_2>
      <PDBx:database_2 database_code="D_1292106174" database_id="WWPDB"></PDBx:database_2>
   </PDBx:database_2Category>
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      <PDBx:diffrn id="1">
         <PDBx:ambient_temp>100</PDBx:ambient_temp>
         <PDBx:crystal_id>1</PDBx:crystal_id>
         <PDBx:pdbx_serial_crystal_experiment>N</PDBx:pdbx_serial_crystal_experiment>
      </PDBx:diffrn>
   </PDBx:diffrnCategory>
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      <PDBx:diffrn_detector diffrn_id="1">
         <PDBx:detector>CCD</PDBx:detector>
         <PDBx:pdbx_collection_date>2007-07-15</PDBx:pdbx_collection_date>
         <PDBx:type>MARRESEARCH</PDBx:type>
      </PDBx:diffrn_detector>
   </PDBx:diffrn_detectorCategory>
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      <PDBx:diffrn_radiation diffrn_id="1">
         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>1.006029</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_synchrotron_beamline>X10SA</PDBx:pdbx_synchrotron_beamline>
         <PDBx:pdbx_synchrotron_site>SLS</PDBx:pdbx_synchrotron_site>
         <PDBx:pdbx_wavelength_list>1.006029</PDBx:pdbx_wavelength_list>
         <PDBx:source>SYNCHROTRON</PDBx:source>
         <PDBx:type>SLS BEAMLINE X10SA</PDBx:type>
      </PDBx:diffrn_source>
   </PDBx:diffrn_sourceCategory>
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         <PDBx:pdbx_description>Dual specificity protein kinase CLK1</PDBx:pdbx_description>
         <PDBx:pdbx_ec>2.7.12.1</PDBx:pdbx_ec>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>man</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="2">
         <PDBx:formula_weight>338.189</PDBx:formula_weight>
         <PDBx:pdbx_description>ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="3">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>216</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_name_comCategory>
      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>CDC-like kinase 1</PDBx:name>
      </PDBx:entity_name_com>
   </PDBx:entity_name_comCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>yes</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCV
QMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAY
NPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLV(SEP)(TPO)RHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFT
VFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKM
LEYDPAKRITLREALKHPFFDLLKKSI</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCV
QMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAY
NPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSK
EHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKR
ITLREALKHPFFDLLKKSI</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>E</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="14">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="15">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="16">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="17">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="18">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="19">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="20">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="21">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="22">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="23">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="24">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="25">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="26">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="27">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="28">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="29">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="30">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="31">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="159">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="160">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="161">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="162">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="163">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="164">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="165">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="166">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="167">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="168">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="169">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="170">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="171">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="172">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="173">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="174">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="175">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="176">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="177">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="178">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="179">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="180">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="181">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="182">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="183">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="184">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="185">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="186">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="187">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="188">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="189">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="190">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="191">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="192">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="193">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="194">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="195">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SEP" num="196">
         <PDBx:hetero>y</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="196">
         <PDBx:hetero>y</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TPO" num="197">
         <PDBx:hetero>y</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="197">
         <PDBx:hetero>y</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="198">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="199">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="200">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="201">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="202">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="203">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="204">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="205">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="206">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="207">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="208">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="209">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="210">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="211">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="212">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="213">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="214">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="215">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="216">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="217">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="218">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="219">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="220">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="221">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="222">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="223">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="224">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="225">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="226">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="227">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="228">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="229">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="230">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="231">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="232">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="233">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="234">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="235">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="236">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="237">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="238">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="239">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="240">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="241">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="242">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="243">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="244">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="245">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="246">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="247">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="248">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="249">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="250">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="251">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="252">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="253">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="254">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="255">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="256">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="257">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="258">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="259">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="260">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="261">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="262">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="263">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="264">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="265">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="266">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="267">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="268">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="269">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="270">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="271">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="272">
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="274">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="276">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="277">
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="280">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="281">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="282">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="283">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="284">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="285">
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="287">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="288">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="289">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="290">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="291">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="292">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="293">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="294">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="295">
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="296">
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      </PDBx:entity_poly_seq>
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      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="312">
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="330">
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
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      </PDBx:entity_poly_seq>
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      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
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      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="2" revision_ordinal="2">
         <PDBx:item>_citation_author.name</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="3" revision_ordinal="3">
         <PDBx:item>_citation.journal_volume</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="4" revision_ordinal="3">
         <PDBx:item>_citation.page_first</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="5" revision_ordinal="3">
         <PDBx:item>_citation.page_last</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
   </PDBx:pdbx_audit_revision_itemCategory>
   <PDBx:pdbx_database_relatedCategory>
      <PDBx:pdbx_database_related content_type="re-refinement" db_id="2VAG" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="6TW2">
         <PDBx:SG_entry>N</PDBx:SG_entry>
         <PDBx:deposit_site>PDBE</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>PDBE</PDBx:process_site>
         <PDBx:recvd_initial_deposition_date>2020-01-12</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>V25</PDBx:comp_id>
         <PDBx:name>ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entry_detailsCategory>
      <PDBx:pdbx_entry_details entry_id="6TW2">
         <PDBx:has_ligand_of_interest>N</PDBx:has_ligand_of_interest>
      </PDBx:pdbx_entry_details>
   </PDBx:pdbx_entry_detailsCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>LIG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2301</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>V25</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>V25</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2045</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2112</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2146</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2012</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2152</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2201</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2162</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2194</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2036</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2132</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2195</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2043</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2129</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2223</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2191</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2153</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2228</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2033</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2214</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2217</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2107</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2157</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2013</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2166</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2032</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2225</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2084</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2163</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2221</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2057</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2042</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2017</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2180</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2058</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2141</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2015</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2030</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2007</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2184</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2119</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2211</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2144</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2230</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2224</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2018</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2226</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2138</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2210</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2075</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2168</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2140</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2155</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2220</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2181</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2016</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2148</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2151</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2167</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2139</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2154</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2165</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2099</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2096</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2207</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2006</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2123</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2024</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2208</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2197</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2010</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2186</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2174</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2004</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2136</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2213</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2025</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2218</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2222</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2053</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2095</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2034</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2074</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2082</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2485</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2173</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2486</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2175</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2487</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2219</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2488</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2005</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2489</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2205</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2490</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2055</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2491</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2105</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2492</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2085</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2493</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2035</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2494</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2023</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2495</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2147</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2496</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2098</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2497</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2498</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2002</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2499</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2083</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2500</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2179</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2150</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2126</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2145</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2504</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2131</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2505</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2081</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2506</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2212</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2507</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2169</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2508</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2106</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2509</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2090</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2510</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="111">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2185</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2511</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="112">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2047</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2512</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="113">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2041</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2513</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="114">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2149</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2514</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="115">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2196</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2515</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="116">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2077</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2516</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="117">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2127</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2517</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="118">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2199</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2518</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="119">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2143</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2519</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="120">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2031</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2520</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="121">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2046</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2521</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="122">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2069</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2522</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="123">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2204</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2523</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="124">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2189</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2524</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="125">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2171</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2525</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="126">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2161</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2526</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="127">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2079</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2527</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="128">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2202</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2528</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="129">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2172</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2529</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="130">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2071</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2530</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="131">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2160</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2531</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="132">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2062</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2532</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="133">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2130</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2533</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="134">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2001</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2534</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="135">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2108</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2535</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="136">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2026</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2536</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="137">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2094</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2537</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="138">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2061</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2538</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="139">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2142</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2539</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="140">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2137</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2540</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="141">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2019</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2541</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="142">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2216</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2542</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="143">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2543</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="144">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2177</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2544</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="145">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2545</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="146">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2076</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2546</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="147">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2117</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2547</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="148">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2118</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2548</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="149">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2068</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2549</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="150">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2176</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2550</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="151">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2052</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2551</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="152">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2078</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2552</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="153">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2121</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2553</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="154">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2156</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2554</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="155">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2014</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2555</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="156">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2109</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2556</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="157">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2115</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2557</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="158">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2060</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2558</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="159">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>15</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2559</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="160">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2059</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2560</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="161">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2227</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2561</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="162">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2124</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2562</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="163">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2563</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="164">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2044</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2564</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="165">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2100</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2565</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="166">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2097</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2566</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="167">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2120</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2567</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="168">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2125</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2568</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="169">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2192</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2569</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="170">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2048</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2570</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="171">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2571</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="172">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2183</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2572</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="173">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2003</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2573</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="174">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2206</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2574</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="175">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2056</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2575</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="176">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2188</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2576</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="177">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2021</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2577</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="178">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2190</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2578</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="179">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2102</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2579</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="180">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2009</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2580</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="181">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2089</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2581</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="182">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2193</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2582</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="183">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2170</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2583</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="184">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2584</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="185">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2198</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2585</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="186">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2128</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2586</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="187">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2133</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2587</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="188">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2588</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="189">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2086</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2589</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="190">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2590</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="191">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2088</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2591</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="192">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2065</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2592</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="193">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2067</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2593</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="194">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2029</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2594</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="195">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2087</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2595</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="196">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2066</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2596</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="197">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2597</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="198">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2598</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="199">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2072</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2599</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="200">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2111</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2600</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="201">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>14</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2601</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="202">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2091</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2602</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="203">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2603</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="204">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2122</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2604</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="205">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2038</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2605</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="206">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2050</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2606</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="207">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2093</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2607</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="208">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2040</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2608</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="209">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2054</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2609</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="210">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2610</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="211">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2135</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2611</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="212">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2092</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2612</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="213">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2063</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2613</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="214">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2134</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2614</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="215">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2080</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2615</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="216">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2103</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2616</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>-1</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="2">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>0</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>0</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="3">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>148</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>148</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="4">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>149</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>149</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="5">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>150</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>150</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="6">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>151</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>151</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="7">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>152</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>152</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="8">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>153</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>153</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="9">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>154</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>154</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="10">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>155</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>155</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="11">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>156</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>156</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="12">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>157</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>157</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="13">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>158</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>158</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="14">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>159</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>159</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="15">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>160</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>160</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="16">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>161</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>161</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="17">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>162</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>162</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="18">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>163</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>163</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="19">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>164</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>164</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="20">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>165</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>165</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="21">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>166</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>166</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="22">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>167</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>167</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="23">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>168</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>168</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="24">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>169</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>169</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="25">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>170</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>170</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="26">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>171</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>171</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="27">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>172</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>172</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="28">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>173</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>173</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="29">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>174</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>174</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="30">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>175</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>175</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="31">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>176</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>176</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="32">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>177</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>177</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="33">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>178</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>178</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="34">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>179</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>179</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="35">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>180</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>180</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="36">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>181</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>181</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="37">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>182</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>182</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="38">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>183</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>183</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="39">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>184</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>184</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="40">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>185</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>185</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="41">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>186</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>186</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="42">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>187</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>187</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="43">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>188</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>188</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="44">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>189</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>189</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="45">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>190</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>190</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="46">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>191</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>191</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="47">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>192</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>192</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="48">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>193</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>193</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="49">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>194</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>194</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="50">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>195</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>195</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="51">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>196</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>196</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="52">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>197</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>197</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="53">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>198</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>198</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="54">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>199</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>199</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="55">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>200</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>200</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="56">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>201</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>201</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="57">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>202</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>202</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="58">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>203</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>203</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="59">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>204</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>204</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="60">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>205</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>205</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="61">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>206</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>206</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="62">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>207</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>207</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="63">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>208</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>208</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="64">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>209</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>209</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="65">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>210</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>210</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="66">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>211</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>211</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="67">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>212</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>212</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="68">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>213</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>213</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="69">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>214</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>214</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="70">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>215</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>215</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="71">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>216</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>216</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="72">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>217</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="73">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>218</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>218</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="74">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>219</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>219</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="75">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>220</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>220</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="76">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>221</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="77">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>222</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>222</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="78">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>223</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>223</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="79">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>224</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>224</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="80">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>225</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>225</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="81">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>226</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>226</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="82">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>227</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>227</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="83">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>228</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>228</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="84">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>229</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>229</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="85">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>230</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>230</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="86">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>231</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>231</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="87">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>232</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>232</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="88">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>233</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>233</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="89">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>234</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>234</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="90">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>235</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>235</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="91">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>236</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>236</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="92">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>237</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>237</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="93">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>238</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>238</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="94">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>239</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>239</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="95">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>240</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>240</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="96">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>241</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>241</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="97">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>242</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>242</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="98">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>243</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>243</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="99">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>244</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>244</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="100">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>245</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>245</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="101">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>246</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>246</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="102">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>247</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>247</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="103">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>248</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>248</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="104">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>249</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>249</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="105">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>250</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>250</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="106">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>251</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>251</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="107">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>252</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>252</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="108">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>253</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>253</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="109">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>254</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>254</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="110">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>255</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>255</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="111">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>256</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>256</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="112">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>257</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>257</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="113">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>258</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>258</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="114">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>259</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>259</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="115">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>260</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>260</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="116">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>261</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>261</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="117">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>262</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>262</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="118">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>263</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>263</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="119">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>264</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>264</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="120">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>265</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>265</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="121">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>266</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>266</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="122">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>267</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>267</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="123">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>268</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>268</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="124">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>269</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>269</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="125">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>270</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>270</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="126">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>271</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>271</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="127">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>272</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>272</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="128">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>273</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>273</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="129">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>274</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>274</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="130">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>275</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>275</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="131">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>276</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>276</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="132">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>277</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>277</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="133">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>278</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>278</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="134">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>279</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>279</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="135">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>280</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>280</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="136">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>281</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>281</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="137">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>282</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>282</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="138">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>283</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>283</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="139">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>284</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>284</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="140">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>285</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>285</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="141">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>286</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>286</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="142">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>287</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>287</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="143">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>288</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>288</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="144">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>289</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>289</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="145">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>290</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>290</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="146">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>291</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>291</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="147">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>292</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>292</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="148">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>293</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>293</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="149">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>294</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>294</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="150">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>295</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>295</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="151">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>296</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>296</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="152">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>297</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>297</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="153">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>298</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>298</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="154">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>299</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>299</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="155">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>300</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>300</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="156">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>301</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="157">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>302</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>302</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="158">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>303</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>303</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="159">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>304</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>304</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="160">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>305</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>305</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="161">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>306</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>306</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="162">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>307</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="163">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>308</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="164">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>309</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="165">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>310</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="166">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>311</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>311</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="167">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>312</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>312</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="168">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>313</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>313</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="169">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>314</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>314</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="170">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>315</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>315</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="171">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>316</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>316</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="172">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>317</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>317</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="173">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>318</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>318</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="174">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>319</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>319</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="175">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>320</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>320</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="176">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>321</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>321</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="177">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>322</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>322</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="178">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>323</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>323</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="179">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>324</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>324</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="180">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>325</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>325</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="181">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>326</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>326</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="182">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>327</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>327</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="183">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>328</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>328</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="184">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>329</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>329</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="185">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>330</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>330</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="186">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>331</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>331</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="187">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>332</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>332</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="188">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>333</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>333</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="189">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>334</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>334</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="190">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>335</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>335</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="191">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>336</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>336</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="192">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>337</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>192</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>337</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="193">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>338</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>193</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>338</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="194">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>339</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>194</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>339</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="195">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>340</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>195</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>340</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SEP" seq_id="196">
         <PDBx:auth_mon_id>SEP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>341</PDBx:auth_seq_num>
         <PDBx:hetero>y</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SEP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>341</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="196">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>341</PDBx:auth_seq_num>
         <PDBx:hetero>y</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>341</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TPO" seq_id="197">
         <PDBx:auth_mon_id>TPO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>342</PDBx:auth_seq_num>
         <PDBx:hetero>y</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TPO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>342</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="197">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>342</PDBx:auth_seq_num>
         <PDBx:hetero>y</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>342</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="198">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>343</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>198</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>343</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="199">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>344</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>199</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>344</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="200">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>345</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>200</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>345</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="201">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>346</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>201</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>346</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="202">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>347</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>202</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>347</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="203">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>348</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>203</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>348</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="204">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>349</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>204</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>349</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="205">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>350</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>205</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>350</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="206">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>351</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>206</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>351</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="207">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>352</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>207</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>352</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="208">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>353</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>208</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>353</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="209">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>354</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>209</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>354</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="210">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>355</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>210</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>355</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="211">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>356</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>211</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>356</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="212">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>357</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>212</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>357</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="213">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>358</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>213</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>358</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="214">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>359</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>214</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>359</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="215">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>360</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>215</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>360</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="216">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>361</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>216</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>361</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="217">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>362</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>217</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>362</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="218">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>363</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>218</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>363</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="219">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>364</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>219</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>364</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="220">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>365</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>220</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>365</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="221">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>366</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>221</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>366</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="222">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>367</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>222</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>367</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="223">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>368</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>223</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>368</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="224">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>369</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>224</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>369</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="225">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>370</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>225</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>370</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="226">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>371</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>226</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="227">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>372</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>227</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="228">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>373</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>228</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="229">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>374</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>229</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="230">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>375</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>230</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="231">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>376</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>231</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="232">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>377</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>232</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="233">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>378</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>233</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="234">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>379</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>234</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="235">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>380</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>235</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="236">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>236</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="237">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>237</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="238">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>238</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="239">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>239</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="240">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>240</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="241">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>241</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="242">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>242</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="243">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>243</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="244">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>244</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="245">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>245</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="246">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>246</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="247">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>247</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="248">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>248</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="249">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>249</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="250">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>250</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="251">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>251</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="252">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>252</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="253">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>253</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="254">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>254</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="255">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>255</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="256">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>256</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="257">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>257</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="258">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>258</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="259">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>259</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="260">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>260</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="261">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>261</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="262">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>262</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="263">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>263</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="264">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>264</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="265">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>265</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="266">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>266</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="267">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>267</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="268">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>268</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="269">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>269</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="270">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>270</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="271">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>271</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="272">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>272</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="273">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>273</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="274">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>274</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="275">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>275</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="276">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>276</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="277">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>277</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="278">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>278</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="279">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>279</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="280">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>280</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="281">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>281</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="282">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>282</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="283">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>283</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="284">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>284</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="285">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>285</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="286">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>286</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="287">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>287</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="288">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>288</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="289">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>289</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="290">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>290</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="291">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>291</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="292">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>292</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="293">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>293</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="294">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>294</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="295">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>295</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="296">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>296</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="297">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>297</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="298">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>298</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="299">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>299</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="300">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>300</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="301">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>301</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="302">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>302</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="303">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>303</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="304">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>304</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="305">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>305</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="306">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>306</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="307">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>307</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="308">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>308</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="309">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>309</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="310">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>455</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>310</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="311">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>456</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>311</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="312">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>457</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>312</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="313">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>458</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>313</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="314">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>459</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>314</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="315">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>460</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>315</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="316">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>461</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>316</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="317">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>462</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>317</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="318">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>463</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>318</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="319">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>464</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>319</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="320">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>465</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>320</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="321">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>466</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>321</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="322">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>467</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>322</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="323">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>468</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>323</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="324">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>469</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>324</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="325">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>470</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>325</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="326">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>471</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>326</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="327">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>472</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>327</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="328">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>473</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>328</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="329">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>474</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>329</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="330">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>475</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>330</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="331">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>476</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>331</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="332">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>477</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>332</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="333">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>478</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>333</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="334">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>479</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>334</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="335">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>480</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>335</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="336">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>481</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>336</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="337">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>482</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>337</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="338">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>483</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>338</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="339">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>484</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>339</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_refine_tlsCategory>
      <PDBx:pdbx_refine_tls id="1">
         <PDBx:L11>1.28360247918</PDBx:L11>
         <PDBx:L12>0.346327532512</PDBx:L12>
         <PDBx:L13>0.0516627653389</PDBx:L13>
         <PDBx:L22>2.15185881748</PDBx:L22>
         <PDBx:L23>0.158422186504</PDBx:L23>
         <PDBx:L33>1.72104651632</PDBx:L33>
         <PDBx:S11>-0.236491865468</PDBx:S11>
         <PDBx:S12>-0.1069164583</PDBx:S12>
         <PDBx:S13>-0.0476238493232</PDBx:S13>
         <PDBx:S21>-0.366564444794</PDBx:S21>
         <PDBx:S22>0.0840447517147</PDBx:S22>
         <PDBx:S23>0.0778981628532</PDBx:S23>
         <PDBx:S31>-0.285104590967</PDBx:S31>
         <PDBx:S32>-0.11142722922</PDBx:S32>
         <PDBx:S33>-0.323564032173</PDBx:S33>
         <PDBx:T11>0.195319682529</PDBx:T11>
         <PDBx:T12>0.0801888236946</PDBx:T12>
         <PDBx:T13>-0.034351977349</PDBx:T13>
         <PDBx:T22>0.143813929224</PDBx:T22>
         <PDBx:T23>-0.0122509020665</PDBx:T23>
         <PDBx:T33>0.120203453986</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>14.4105004445</PDBx:origin_x>
         <PDBx:origin_y>6.64873866416</PDBx:origin_y>
         <PDBx:origin_z>14.7635358718</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
   </PDBx:pdbx_refine_tlsCategory>
   <PDBx:pdbx_refine_tls_groupCategory>
      <PDBx:pdbx_refine_tls_group id="1">
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
         <PDBx:selection_details>(chain &apos;E&apos; and resid 0 through 484)</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
   </PDBx:pdbx_refine_tls_groupCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_and_software_defined_assembly</PDBx:details>
         <PDBx:method_details>PISA</PDBx:method_details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_auth_evidenceCategory>
      <PDBx:pdbx_struct_assembly_auth_evidence assembly_id="1" id="1">
         <PDBx:experimental_support>gel filtration</PDBx:experimental_support>
      </PDBx:pdbx_struct_assembly_auth_evidence>
   </PDBx:pdbx_struct_assembly_auth_evidenceCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_assembly_propCategory>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="ABSA (A^2)">
         <PDBx:value>740</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="MORE">
         <PDBx:value>-16</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="SSA (A^2)">
         <PDBx:value>16090</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
   </PDBx:pdbx_struct_assembly_propCategory>
   <PDBx:pdbx_struct_mod_residueCategory>
      <PDBx:pdbx_struct_mod_residue id="1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SEP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>341</PDBx:auth_seq_id>
         <PDBx:details>modified residue</PDBx:details>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SEP</PDBx:label_comp_id>
         <PDBx:label_seq_id>196</PDBx:label_seq_id>
         <PDBx:parent_comp_id>SER</PDBx:parent_comp_id>
      </PDBx:pdbx_struct_mod_residue>
      <PDBx:pdbx_struct_mod_residue id="2">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TPO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>342</PDBx:auth_seq_id>
         <PDBx:details>modified residue</PDBx:details>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>TPO</PDBx:label_comp_id>
         <PDBx:label_seq_id>197</PDBx:label_seq_id>
         <PDBx:parent_comp_id>THR</PDBx:parent_comp_id>
      </PDBx:pdbx_struct_mod_residue>
   </PDBx:pdbx_struct_mod_residueCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>157</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>12</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>TYR</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>161</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>TYR</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>16</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>164</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>19</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>GLU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>177</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>GLU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>32</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="3" range_id_2="4" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LYS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>174</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LYS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>29</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>192</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>47</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="4" range_id_2="5" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ALA</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>189</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ALA</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>44</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>PHE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>241</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>PHE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>96</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="5" range_id_2="6" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>240</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>95</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>228</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>83</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>THR</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>285</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>THR</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>140</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>THR</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>330</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>THR</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>185</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA3">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>295</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>150</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LYS</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>322</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LYS</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>177</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA4">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ALA</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>304</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ALA</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>159</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>GLU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>313</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>GLU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>168</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA5">
         <PDBx:range_1_auth_asym_id>E</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>HIS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>413</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>HIS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>268</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>E</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ARG</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>416</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ARG</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>271</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>-1</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>307</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>162</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>308</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>163</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>309</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>164</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>310</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>165</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
   </PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
   <PDBx:pdbx_validate_close_contactCategory>
      <PDBx:pdbx_validate_close_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>E</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>E</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>346</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>384</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:label_alt_id_1>A</PDBx:label_alt_id_1>
      </PDBx:pdbx_validate_close_contact>
   </PDBx:pdbx_validate_close_contactCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>160</PDBx:auth_seq_id>
         <PDBx:phi>-150.42</PDBx:phi>
         <PDBx:psi>-43.12</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>229</PDBx:auth_seq_id>
         <PDBx:phi>-174.84</PDBx:phi>
         <PDBx:psi>-179.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>287</PDBx:auth_seq_id>
         <PDBx:phi>77.69</PDBx:phi>
         <PDBx:psi>-11.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>325</PDBx:auth_seq_id>
         <PDBx:phi>68.10</PDBx:phi>
         <PDBx:psi>86.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SEP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>341</PDBx:auth_seq_id>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:phi>-72.13</PDBx:phi>
         <PDBx:psi>-163.07</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>341</PDBx:auth_seq_id>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:phi>77.14</PDBx:phi>
         <PDBx:psi>130.96</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>357</PDBx:auth_seq_id>
         <PDBx:phi>-158.21</PDBx:phi>
         <PDBx:psi>-144.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:label_alt_id>A</PDBx:label_alt_id>
         <PDBx:phi>60.61</PDBx:phi>
         <PDBx:psi>-135.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:label_alt_id>B</PDBx:label_alt_id>
         <PDBx:phi>61.59</PDBx:phi>
         <PDBx:psi>-133.99</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="6TW2" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_mean>35.75</PDBx:B_iso_mean>
         <PDBx:ls_R_factor_R_free>0.2225</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.1806</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.1828</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.80</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>29.27</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>1887</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_obs>36956</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>5.11</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>99.88</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_ML>0.2533</PDBx:overall_SU_ML>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>FREE R-VALUE</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>1.38</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>FOURIER SYNTHESIS</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_phase_error>23.2524</PDBx:pdbx_overall_phase_error>
         <PDBx:pdbx_solvent_shrinkage_radii>0.9000</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.1100</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_starting_model>2VAG</PDBx:pdbx_starting_model>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.80</PDBx:d_res_high>
         <PDBx:d_res_low>29.27</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>216</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>3002</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>22</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>2764</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_bond_d">
         <PDBx:dev_ideal>0.0078</PDBx:dev_ideal>
         <PDBx:number>3136</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_angle_d">
         <PDBx:dev_ideal>0.9291</PDBx:dev_ideal>
         <PDBx:number>4274</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_chiral_restr">
         <PDBx:dev_ideal>0.0571</PDBx:dev_ideal>
         <PDBx:number>452</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_plane_restr">
         <PDBx:dev_ideal>0.0056</PDBx:dev_ideal>
         <PDBx:number>557</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_dihedral_angle_d">
         <PDBx:dev_ideal>14.5404</PDBx:dev_ideal>
         <PDBx:number>1880</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.80" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.3648</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.3311</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>1.85</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>154</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2666</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>99.44</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="1.85" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2870</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2764</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>1.91</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>142</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2662</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>99.64</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="1.91" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2617</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2267</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>1.97</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>128</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2711</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="1.97" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2404</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2118</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.04</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>154</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2665</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.04" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2445</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2026</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.12</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>136</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2713</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.12" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2376</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1968</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.22</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>127</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2717</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.22" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2454</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1879</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.33</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>143</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2679</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.33" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2515</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1823</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.48</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>153</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2684</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.48" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2175</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1892</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.67</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>151</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2699</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.67" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2736</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1916</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.94</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>148</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2692</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.94" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2537</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1850</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>3.36</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>156</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2689</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="3.36" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.1687</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1436</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>4.24</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>151</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2734</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="4.24" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.1752</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1509</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>29.27</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>144</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2758</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_R_complete xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>99.38</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:B_iso_Wilson_estimate>25.61</PDBx:B_iso_Wilson_estimate>
         <PDBx:d_resolution_high>1.80</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>30.0</PDBx:d_resolution_low>
         <PDBx:entry_id>6TW2</PDBx:entry_id>
         <PDBx:number_obs>36979</PDBx:number_obs>
         <PDBx:pdbx_Rmerge_I_obs>0.09</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>11.6</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_redundancy>3.8</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>99.9</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.613</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.80</PDBx:d_res_high>
         <PDBx:d_res_low>1.92</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>1.8</PDBx:meanI_over_sigI_obs>
         <PDBx:number_unique_obs>5380</PDBx:number_unique_obs>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>3.0</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>99.9</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:version>1.16_3549</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>phasing</PDBx:classification>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:version>1.16_3549</PDBx:version>
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:space_groupCategory>
      <PDBx:space_group id="1">
         <PDBx:IT_number>5</PDBx:IT_number>
         <PDBx:crystal_system>monoclinic</PDBx:crystal_system>
         <PDBx:name_H-M_alt>C 1 2 1</PDBx:name_H-M_alt>
         <PDBx:name_Hall>C 2y</PDBx:name_Hall>
      </PDBx:space_group>
   </PDBx:space_groupCategory>
   <PDBx:space_group_symopCategory>
      <PDBx:space_group_symop id="1">
         <PDBx:operation_xyz>x,y,z</PDBx:operation_xyz>
      </PDBx:space_group_symop>
      <PDBx:space_group_symop id="2">
         <PDBx:operation_xyz>-x,y,-z</PDBx:operation_xyz>
      </PDBx:space_group_symop>
      <PDBx:space_group_symop id="3">
         <PDBx:operation_xyz>x+1/2,y+1/2,z</PDBx:operation_xyz>
      </PDBx:space_group_symop>
      <PDBx:space_group_symop id="4">
         <PDBx:operation_xyz>-x+1/2,y+1/2,-z</PDBx:operation_xyz>
      </PDBx:space_group_symop>
   </PDBx:space_group_symopCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="6TW2">
         <PDBx:pdbx_CASP_flag>N</PDBx:pdbx_CASP_flag>
         <PDBx:pdbx_descriptor>Dual specificity protein kinase CLK1 (E.C.2.7.12.1)</PDBx:pdbx_descriptor>
         <PDBx:title>Re-refined crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>MET</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>MET</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>2</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>CYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>151</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>CYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>6</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>196</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>51</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>217</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>72</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>22</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>247</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>102</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>255</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>110</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>9</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P4">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ARG</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>261</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ARG</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>116</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>282</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>137</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>22</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P5">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>290</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>145</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>292</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>147</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>3</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P6">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ALA</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>347</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ALA</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>202</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>352</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>207</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P7">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>358</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>213</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>375</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>230</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA7</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>18</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P8">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>383</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>238</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>396</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>251</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA8</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>14</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P9">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>399</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>254</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>THR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>406</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>THR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>261</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA9</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>8</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P10">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>408</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>263</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>410</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>265</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>3</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P11">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>423</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>278</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>CYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>433</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>CYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>288</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>11</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P12">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>435</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>290</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>MET</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>440</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>MET</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>295</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P13">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>444</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>299</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>458</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>313</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>15</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P14">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>467</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>322</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>472</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>327</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P15">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>473</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>328</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>481</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>336</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>9</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_connCategory>
      <PDBx:struct_conn id="covale1">
         <PDBx:conn_type_id>covale</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>1.325</PDBx:pdbx_dist_value>
         <PDBx:pdbx_leaving_atom_flag>both</PDBx:pdbx_leaving_atom_flag>
         <PDBx:pdbx_ptnr1_label_alt_id>A</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:pdbx_ptnr2_label_alt_id>A</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>VAL</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>340</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>C</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>VAL</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>195</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>SEP</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>341</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>N</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>SEP</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>196</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="covale2">
         <PDBx:conn_type_id>covale</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>1.330</PDBx:pdbx_dist_value>
         <PDBx:pdbx_leaving_atom_flag>both</PDBx:pdbx_leaving_atom_flag>
         <PDBx:pdbx_ptnr1_label_alt_id>A</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:pdbx_ptnr2_label_alt_id>A</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>SEP</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>341</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>C</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>SEP</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>196</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>TPO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>342</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>N</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>TPO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>197</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="covale3">
         <PDBx:conn_type_id>covale</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>1.323</PDBx:pdbx_dist_value>
         <PDBx:pdbx_leaving_atom_flag>both</PDBx:pdbx_leaving_atom_flag>
         <PDBx:pdbx_ptnr1_label_alt_id>A</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:pdbx_ptnr2_label_alt_id>A</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>TPO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>342</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>C</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>TPO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>197</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ARG</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>343</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>N</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ARG</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>198</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
   </PDBx:struct_connCategory>
   <PDBx:struct_conn_typeCategory>
      <PDBx:struct_conn_type id="covale">
      </PDBx:struct_conn_type>
   </PDBx:struct_conn_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="6TW2">
         <PDBx:pdbx_keywords>TRANSFERASE</PDBx:pdbx_keywords>
         <PDBx:text>SERINE/THREONINE-PROTEIN KINASE, TYROSINE-PROTEIN KINASE, NUCLEUS, TRANSFERASE</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>CLK1_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>148</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P49759</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>HLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQM
LEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNP
KIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEH
LAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRIT
LREALKHPFFDLLKKSI</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>148</PDBx:db_align_beg>
         <PDBx:db_align_end>484</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>6TW2</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>148</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>484</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P49759</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>E</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>3</PDBx:seq_align_beg>
         <PDBx:seq_align_end>339</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>expression tag</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>-1</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>6TW2</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>E</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P49759</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>1</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>expression tag</PDBx:details>
         <PDBx:mon_id>MET</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>0</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>6TW2</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>E</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P49759</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>2</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="3">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>ARG</PDBx:db_mon_id>
         <PDBx:details>variant</PDBx:details>
         <PDBx:mon_id>ALA</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>432</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>6TW2</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>E</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P49759</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>432</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>287</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="AA1">
         <PDBx:number_strands>6</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA2">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA3">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA4">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA5">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="4" range_id_2="5" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="5" range_id_2="6" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA3">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA4">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA5">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>156</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>11</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>157</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>12</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>TYR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>161</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>TYR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>16</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>170</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>25</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>173</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>28</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>180</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>35</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>187</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>42</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>193</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>48</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="5" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>236</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>91</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>242</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>97</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="6" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>MET</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>227</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>MET</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>82</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>HIS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>233</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>HIS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>88</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>284</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>139</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>THR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>285</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>THR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>140</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>330</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>185</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TYR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>331</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TYR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>186</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA3">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>294</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>149</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>PHE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>296</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>PHE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>151</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA3">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>321</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>176</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>323</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>178</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA4">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>TYR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>301</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>TYR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>156</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>304</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>159</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA4">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>313</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>168</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>316</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>171</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA5">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PHE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>412</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PHE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>267</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>HIS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>413</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>HIS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>268</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA5">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ARG</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>416</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ARG</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>271</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>417</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>272</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>binding site for residue V25 E 2301</PDBx:details>
         <PDBx:pdbx_auth_asym_id>E</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>V25</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>2301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>13</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>167</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>22</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>168</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>23</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>24</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>175</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>30</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>189</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>44</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>191</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>46</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>241</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_seq_id>96</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>242</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>97</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>292</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>147</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>293</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>148</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>295</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>324</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>179</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>13</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="6TW2">
         <PDBx:Int_Tables_number>5</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>C 1 2 1</PDBx:space_group_name_H-M>
         <PDBx:space_group_name_Hall>C 2y</PDBx:space_group_name_Hall>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
