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         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>23</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="50">
         <PDBx:B_iso_or_equiv>50.00</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-1.551</PDBx:Cartn_x>
         <PDBx:Cartn_y>48.775</PDBx:Cartn_y>
         <PDBx:Cartn_z>40.489</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>23</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="51">
         <PDBx:B_iso_or_equiv>44.24</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-2.736</PDBx:Cartn_x>
         <PDBx:Cartn_y>48.962</PDBx:Cartn_y>
         <PDBx:Cartn_z>40.883</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>23</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="52">
         <PDBx:B_iso_or_equiv>41.88</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-0.418</PDBx:Cartn_x>
         <PDBx:Cartn_y>49.147</PDBx:Cartn_y>
         <PDBx:Cartn_z>41.144</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>23</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="53">
         <PDBx:B_iso_or_equiv>20.60</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>0.131</PDBx:Cartn_x>
         <PDBx:Cartn_y>45.203</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.904</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="54">
         <PDBx:B_iso_or_equiv>23.12</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>1.401</PDBx:Cartn_x>
         <PDBx:Cartn_y>44.425</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.840</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="55">
         <PDBx:B_iso_or_equiv>26.23</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>1.953</PDBx:Cartn_x>
         <PDBx:Cartn_y>43.833</PDBx:Cartn_y>
         <PDBx:Cartn_z>39.130</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="56">
         <PDBx:B_iso_or_equiv>23.83</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.699</PDBx:Cartn_x>
         <PDBx:Cartn_y>42.836</PDBx:Cartn_y>
         <PDBx:Cartn_z>39.107</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="57">
         <PDBx:B_iso_or_equiv>22.68</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.581</PDBx:Cartn_x>
         <PDBx:Cartn_y>45.187</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.257</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="58">
         <PDBx:B_iso_or_equiv>22.03</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.465</PDBx:Cartn_x>
         <PDBx:Cartn_y>45.130</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.758</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="59">
         <PDBx:B_iso_or_equiv>19.69</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.594</PDBx:Cartn_x>
         <PDBx:Cartn_y>45.925</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.096</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="60">
         <PDBx:B_iso_or_equiv>25.66</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.237</PDBx:Cartn_x>
         <PDBx:Cartn_y>46.022</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.693</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="61">
         <PDBx:B_iso_or_equiv>25.93</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.477</PDBx:Cartn_x>
         <PDBx:Cartn_y>45.035</PDBx:Cartn_y>
         <PDBx:Cartn_z>32.820</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="62">
         <PDBx:B_iso_or_equiv>17.62</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>4.154</PDBx:Cartn_x>
         <PDBx:Cartn_y>43.956</PDBx:Cartn_y>
         <PDBx:Cartn_z>33.233</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="63">
         <PDBx:B_iso_or_equiv>24.74</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.052</PDBx:Cartn_x>
         <PDBx:Cartn_y>45.174</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.549</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>24</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="64">
         <PDBx:B_iso_or_equiv>28.40</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>1.786</PDBx:Cartn_x>
         <PDBx:Cartn_y>44.619</PDBx:Cartn_y>
         <PDBx:Cartn_z>40.177</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>25</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="65">
         <PDBx:B_iso_or_equiv>27.20</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.513</PDBx:Cartn_x>
         <PDBx:Cartn_y>44.393</PDBx:Cartn_y>
         <PDBx:Cartn_z>41.414</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="147">
         <PDBx:B_iso_or_equiv>11.35</PDBx:B_iso_or_equiv>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="148">
         <PDBx:B_iso_or_equiv>10.53</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_z>28.475</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="149">
         <PDBx:B_iso_or_equiv>5.96</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>3.580</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.162</PDBx:Cartn_y>
         <PDBx:Cartn_z>30.779</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="150">
         <PDBx:B_iso_or_equiv>19.03</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.380</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.211</PDBx:Cartn_y>
         <PDBx:Cartn_z>29.855</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="151">
         <PDBx:B_iso_or_equiv>13.16</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>1.299</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.965</PDBx:Cartn_y>
         <PDBx:Cartn_z>30.225</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="152">
         <PDBx:B_iso_or_equiv>18.04</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.371</PDBx:Cartn_x>
         <PDBx:Cartn_y>20.540</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.639</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="153">
         <PDBx:B_iso_or_equiv>14.17</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>0.208</PDBx:Cartn_x>
         <PDBx:Cartn_y>22.072</PDBx:Cartn_y>
         <PDBx:Cartn_z>29.414</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="154">
         <PDBx:B_iso_or_equiv>23.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>1.250</PDBx:Cartn_x>
         <PDBx:Cartn_y>20.614</PDBx:Cartn_y>
         <PDBx:Cartn_z>27.819</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="155">
         <PDBx:B_iso_or_equiv>29.71</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>0.168</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.408</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.224</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="156">
         <PDBx:B_iso_or_equiv>26.70</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-0.966</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.550</PDBx:Cartn_y>
         <PDBx:Cartn_z>27.442</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OH</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>35</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OH</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>20</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="157">
         <PDBx:B_iso_or_equiv>20.98</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.016</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.695</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.937</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="158">
         <PDBx:B_iso_or_equiv>20.63</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.720</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.714</PDBx:Cartn_y>
         <PDBx:Cartn_z>27.650</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="159">
         <PDBx:B_iso_or_equiv>18.95</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.855</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.044</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.608</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="160">
         <PDBx:B_iso_or_equiv>20.32</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.585</PDBx:Cartn_x>
         <PDBx:Cartn_y>19.845</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.773</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="161">
         <PDBx:B_iso_or_equiv>17.41</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.058</PDBx:Cartn_x>
         <PDBx:Cartn_y>20.986</PDBx:Cartn_y>
         <PDBx:Cartn_z>27.735</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="162">
         <PDBx:B_iso_or_equiv>19.83</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.050</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.526</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.713</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="163">
         <PDBx:B_iso_or_equiv>36.98</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.776</PDBx:Cartn_x>
         <PDBx:Cartn_y>20.332</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.061</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="164">
         <PDBx:B_iso_or_equiv>32.47</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.046</PDBx:Cartn_x>
         <PDBx:Cartn_y>19.183</PDBx:Cartn_y>
         <PDBx:Cartn_z>27.001</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="165">
         <PDBx:B_iso_or_equiv>26.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.089</PDBx:Cartn_x>
         <PDBx:Cartn_y>17.886</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.599</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="166">
         <PDBx:B_iso_or_equiv>31.52</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.812</PDBx:Cartn_x>
         <PDBx:Cartn_y>17.535</PDBx:Cartn_y>
         <PDBx:Cartn_z>25.324</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="167">
         <PDBx:B_iso_or_equiv>26.69</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.167</PDBx:Cartn_x>
         <PDBx:Cartn_y>16.913</PDBx:Cartn_y>
         <PDBx:Cartn_z>27.476</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>21</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="168">
         <PDBx:B_iso_or_equiv>28.13</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.233</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.881</PDBx:Cartn_y>
         <PDBx:Cartn_z>25.772</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>22</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="169">
         <PDBx:B_iso_or_equiv>37.53</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>4.186</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.418</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.887</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>22</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="170">
         <PDBx:B_iso_or_equiv>40.93</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>4.668</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.381</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.446</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>22</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="171">
         <PDBx:B_iso_or_equiv>34.88</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>4.772</PDBx:Cartn_x>
         <PDBx:Cartn_y>22.455</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.830</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>22</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="172">
         <PDBx:B_iso_or_equiv>35.92</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>2.927</PDBx:Cartn_x>
         <PDBx:Cartn_y>22.308</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.984</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>22</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="173">
         <PDBx:B_iso_or_equiv>42.21</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>1.878</PDBx:Cartn_x>
         <PDBx:Cartn_y>21.722</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.203</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OG</PDBx:label_atom_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>22</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="174">
         <PDBx:B_iso_or_equiv>33.34</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.091</PDBx:Cartn_x>
         <PDBx:Cartn_y>20.169</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.044</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>23</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>B</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="175">
         <PDBx:B_iso_or_equiv>28.61</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.772</PDBx:Cartn_x>
         <PDBx:Cartn_y>20.005</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.774</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>23</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>B</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="176">
         <PDBx:B_iso_or_equiv>34.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.186</PDBx:Cartn_x>
         <PDBx:Cartn_y>20.561</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.857</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>23</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>B</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="177">
         <PDBx:B_iso_or_equiv>33.39</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.060</PDBx:Cartn_x>
         <PDBx:Cartn_y>19.934</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.509</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>36</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>23</PDBx:label_seq_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>47</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>47</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>47</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>47</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="263">
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         <PDBx:Cartn_z>49.375</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="264">
         <PDBx:B_iso_or_equiv>5.31</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>29.857</PDBx:Cartn_y>
         <PDBx:Cartn_z>49.692</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
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         <PDBx:Cartn_z>48.425</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>47.362</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:Cartn_z>50.146</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>51.633</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>28.265</PDBx:Cartn_y>
         <PDBx:Cartn_z>52.377</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>28.045</PDBx:Cartn_y>
         <PDBx:Cartn_z>53.819</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="271">
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         <PDBx:Cartn_z>54.617</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="272">
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         <PDBx:Cartn_z>54.089</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="273">
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         <PDBx:Cartn_y>27.827</PDBx:Cartn_y>
         <PDBx:Cartn_z>55.921</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>48</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>36</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="274">
         <PDBx:B_iso_or_equiv>13.33</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.692</PDBx:Cartn_x>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>61</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>61</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>61</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>62</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>35.578</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>35.413</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>34.839</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:B_iso_or_equiv>4.00</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.319</PDBx:Cartn_x>
         <PDBx:Cartn_y>26.507</PDBx:Cartn_y>
         <PDBx:Cartn_z>32.609</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="420">
         <PDBx:B_iso_or_equiv>14.18</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.174</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.324</PDBx:Cartn_y>
         <PDBx:Cartn_z>31.657</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="421">
         <PDBx:B_iso_or_equiv>19.74</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.354</PDBx:Cartn_x>
         <PDBx:Cartn_y>28.185</PDBx:Cartn_y>
         <PDBx:Cartn_z>30.775</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="422">
         <PDBx:B_iso_or_equiv>23.41</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.856</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.039</PDBx:Cartn_y>
         <PDBx:Cartn_z>29.856</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="423">
         <PDBx:B_iso_or_equiv>18.39</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.197</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.211</PDBx:Cartn_y>
         <PDBx:Cartn_z>29.676</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="424">
         <PDBx:B_iso_or_equiv>14.56</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.994</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.759</PDBx:Cartn_y>
         <PDBx:Cartn_z>29.107</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>65</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_ins_code>A</PDBx:pdbx_PDB_ins_code>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="425">
         <PDBx:B_iso_or_equiv>7.25</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.066</PDBx:Cartn_x>
         <PDBx:Cartn_y>26.847</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.250</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>66</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="426">
         <PDBx:B_iso_or_equiv>4.00</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.361</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.862</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.954</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>66</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="427">
         <PDBx:B_iso_or_equiv>4.43</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.857</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.201</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.454</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>66</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="428">
         <PDBx:B_iso_or_equiv>8.13</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.062</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.441</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.301</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>66</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="429">
         <PDBx:B_iso_or_equiv>4.00</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.664</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.654</PDBx:Cartn_y>
         <PDBx:Cartn_z>38.467</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>66</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="430">
         <PDBx:B_iso_or_equiv>11.33</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.535</PDBx:Cartn_x>
         <PDBx:Cartn_y>28.891</PDBx:Cartn_y>
         <PDBx:Cartn_z>39.336</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>66</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="431">
         <PDBx:B_iso_or_equiv>4.00</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.017</PDBx:Cartn_x>
         <PDBx:Cartn_y>26.365</PDBx:Cartn_y>
         <PDBx:Cartn_z>39.040</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>66</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="432">
         <PDBx:B_iso_or_equiv>9.74</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.903</PDBx:Cartn_x>
         <PDBx:Cartn_y>30.090</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.217</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>67</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>56</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="433">
         <PDBx:B_iso_or_equiv>14.64</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.213</PDBx:Cartn_x>
         <PDBx:Cartn_y>31.480</PDBx:Cartn_y>
         <PDBx:Cartn_z>35.912</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>67</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>56</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="434">
         <PDBx:B_iso_or_equiv>4.84</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.764</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.410</PDBx:Cartn_y>
         <PDBx:Cartn_z>37.038</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>67</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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         <PDBx:Cartn_z>44.495</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="762">
         <PDBx:B_iso_or_equiv>9.45</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>22.289</PDBx:Cartn_y>
         <PDBx:Cartn_z>44.746</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>98</PDBx:label_seq_id>
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      <PDBx:atom_site id="763">
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         <PDBx:Cartn_y>22.737</PDBx:Cartn_y>
         <PDBx:Cartn_z>43.419</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>42.481</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>45.436</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>46.273</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>47.613</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>47.954</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>47.030</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>22.332</PDBx:Cartn_y>
         <PDBx:Cartn_z>49.264</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="772">
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         <PDBx:Cartn_y>24.018</PDBx:Cartn_y>
         <PDBx:Cartn_z>43.333</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>108</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="773">
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
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         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>5</PDBx:label_entity_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2013">
         <PDBx:B_iso_or_equiv>33.64</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-21.926</PDBx:Cartn_x>
         <PDBx:Cartn_y>42.240</PDBx:Cartn_y>
         <PDBx:Cartn_z>52.475</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>701</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>5</PDBx:label_entity_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2014">
         <PDBx:B_iso_or_equiv>33.46</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-23.528</PDBx:Cartn_x>
         <PDBx:Cartn_y>17.097</PDBx:Cartn_y>
         <PDBx:Cartn_z>36.217</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>702</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>5</PDBx:label_entity_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2015">
         <PDBx:B_iso_or_equiv>34.04</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>-0.671</PDBx:Cartn_x>
         <PDBx:Cartn_y>35.420</PDBx:Cartn_y>
         <PDBx:Cartn_z>43.921</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>703</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>5</PDBx:label_entity_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2016">
         <PDBx:B_iso_or_equiv>24.87</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.309</PDBx:Cartn_x>
         <PDBx:Cartn_y>41.962</PDBx:Cartn_y>
         <PDBx:Cartn_z>41.381</PDBx:Cartn_z>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>706</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_entity_id>5</PDBx:label_entity_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
   </PDBx:atom_siteCategory>
   <PDBx:atom_sitesCategory>
      <PDBx:atom_sites entry_id="8EST">
         <PDBx:fract_transf_matrix11>0.019755</PDBx:fract_transf_matrix11>
         <PDBx:fract_transf_matrix12>0.000000</PDBx:fract_transf_matrix12>
         <PDBx:fract_transf_matrix13>0.000000</PDBx:fract_transf_matrix13>
         <PDBx:fract_transf_matrix21>0.000000</PDBx:fract_transf_matrix21>
         <PDBx:fract_transf_matrix22>0.017164</PDBx:fract_transf_matrix22>
         <PDBx:fract_transf_matrix23>0.000000</PDBx:fract_transf_matrix23>
         <PDBx:fract_transf_matrix31>0.000000</PDBx:fract_transf_matrix31>
         <PDBx:fract_transf_matrix32>0.000000</PDBx:fract_transf_matrix32>
         <PDBx:fract_transf_matrix33>0.013291</PDBx:fract_transf_matrix33>
         <PDBx:fract_transf_vector1>0.00000</PDBx:fract_transf_vector1>
         <PDBx:fract_transf_vector2>0.00000</PDBx:fract_transf_vector2>
         <PDBx:fract_transf_vector3>0.00000</PDBx:fract_transf_vector3>
      </PDBx:atom_sites>
   </PDBx:atom_sitesCategory>
   <PDBx:atom_sites_footnoteCategory>
      <PDBx:atom_sites_footnote id="1">
         <PDBx:text>THE FOLLOWING ATOMS WERE TREATED AS DUMMY ATOMS, WHICH MEANS THAT THEY CONTRIBUTED TO THE ENERGY REFINEMENT PART OF EREF BUT NOT TO THE CALCULATED STRUCTURE FACTORS -SER 36C OG, SER 37 OG, ARG 61 (CZ,NH1,NH2), GLN 110 (CG,CD,OE1,NE2), ARG 125 (CG,CD,NE,CZ,NH1,NH2), SO4 247 (O1,O3).</PDBx:text>
      </PDBx:atom_sites_footnote>
   </PDBx:atom_sites_footnoteCategory>
   <PDBx:atom_typeCategory>
      <PDBx:atom_type symbol="C"></PDBx:atom_type>
      <PDBx:atom_type symbol="CA"></PDBx:atom_type>
      <PDBx:atom_type symbol="CL"></PDBx:atom_type>
      <PDBx:atom_type symbol="N"></PDBx:atom_type>
      <PDBx:atom_type symbol="O"></PDBx:atom_type>
      <PDBx:atom_type symbol="S"></PDBx:atom_type>
   </PDBx:atom_typeCategory>
   <PDBx:audit_authorCategory>
      <PDBx:audit_author pdbx_ordinal="1">
         <PDBx:name>Radhakrishnan, R.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="2">
         <PDBx:name>Powers, J.C.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="3">
         <PDBx:name>Meyerjunior, E.F.</PDBx:name>
      </PDBx:audit_author>
   </PDBx:audit_authorCategory>
   <PDBx:audit_conformCategory>
      <PDBx:audit_conform dict_name="mmcif_pdbx.dic" dict_version="5.279">
         <PDBx:dict_location>http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic</PDBx:dict_location>
      </PDBx:audit_conform>
   </PDBx:audit_conformCategory>
   <PDBx:cellCategory>
      <PDBx:cell entry_id="8EST">
         <PDBx:Z_PDB>4</PDBx:Z_PDB>
         <PDBx:angle_alpha>90.00</PDBx:angle_alpha>
         <PDBx:angle_beta>90.00</PDBx:angle_beta>
         <PDBx:angle_gamma>90.00</PDBx:angle_gamma>
         <PDBx:length_a>50.620</PDBx:length_a>
         <PDBx:length_b>58.260</PDBx:length_b>
         <PDBx:length_c>75.240</PDBx:length_c>
      </PDBx:cell>
   </PDBx:cellCategory>
   <PDBx:chem_compCategory>
      <PDBx:chem_comp id="ALA">
         <PDBx:formula>C3 H7 N O2</PDBx:formula>
         <PDBx:formula_weight>89.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ARG">
         <PDBx:formula>C6 H15 N4 O2 1</PDBx:formula>
         <PDBx:formula_weight>175.209</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ARGININE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASN">
         <PDBx:formula>C4 H8 N2 O3</PDBx:formula>
         <PDBx:formula_weight>132.118</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARAGINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASP">
         <PDBx:formula>C4 H7 N O4</PDBx:formula>
         <PDBx:formula_weight>133.103</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARTIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="CA">
         <PDBx:formula>Ca 2</PDBx:formula>
         <PDBx:formula_weight>40.078</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>CALCIUM ION</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="CYS">
         <PDBx:formula>C3 H7 N O2 S</PDBx:formula>
         <PDBx:formula_weight>121.158</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>CYSTEINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GIS">
         <PDBx:formula>C12 H14 Cl N3 O4</PDBx:formula>
         <PDBx:formula_weight>299.710</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>ETHYL-(2-CARBOXY-4-GUANIDINIUM-PHENYL)-CHLOROACETATE</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLN">
         <PDBx:formula>C5 H10 N2 O3</PDBx:formula>
         <PDBx:formula_weight>146.144</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLU">
         <PDBx:formula>C5 H9 N O4</PDBx:formula>
         <PDBx:formula_weight>147.129</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLY">
         <PDBx:formula>C2 H5 N O2</PDBx:formula>
         <PDBx:formula_weight>75.067</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLYCINE</PDBx:name>
         <PDBx:type>peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HIS">
         <PDBx:formula>C6 H10 N3 O2 1</PDBx:formula>
         <PDBx:formula_weight>156.162</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>HISTIDINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HOH">
         <PDBx:formula>H2 O</PDBx:formula>
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>WATER</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ILE">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ISOLEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LEU">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LYS">
         <PDBx:formula>C6 H15 N2 O2 1</PDBx:formula>
         <PDBx:formula_weight>147.195</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LYSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="MET">
         <PDBx:formula>C5 H11 N O2 S</PDBx:formula>
         <PDBx:formula_weight>149.211</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>METHIONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PHE">
         <PDBx:formula>C9 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>165.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PHENYLALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PRO">
         <PDBx:formula>C5 H9 N O2</PDBx:formula>
         <PDBx:formula_weight>115.130</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PROLINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="SER">
         <PDBx:formula>C3 H7 N O3</PDBx:formula>
         <PDBx:formula_weight>105.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>SERINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="SO4">
         <PDBx:formula>O4 S -2</PDBx:formula>
         <PDBx:formula_weight>96.063</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>SULFATE ION</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="THR">
         <PDBx:formula>C4 H9 N O3</PDBx:formula>
         <PDBx:formula_weight>119.119</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>THREONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TRP">
         <PDBx:formula>C11 H12 N2 O2</PDBx:formula>
         <PDBx:formula_weight>204.225</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TRYPTOPHAN</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TYR">
         <PDBx:formula>C9 H11 N O3</PDBx:formula>
         <PDBx:formula_weight>181.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TYROSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="VAL">
         <PDBx:formula>C5 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>117.146</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>VALINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
   </PDBx:chem_compCategory>
   <PDBx:citationCategory>
      <PDBx:citation id="primary">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>Biochemistry</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>BICHAW</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0033</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0006-2960</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>29</PDBx:journal_volume>
         <PDBx:page_first>3108</PDBx:page_first>
         <PDBx:page_last>3118</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1021/bi00464a030</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>2337582</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin.</PDBx:title>
         <PDBx:year>1990</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="1">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>J.Med.Chem.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMCMAR</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0151</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0022-2623</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>35</PDBx:journal_volume>
         <PDBx:page_first>1121</PDBx:page_first>
         <PDBx:title>Effect of the 7-Amino Substituent on the Inhibitory Potency of Mechanism-Based Isocoumarin Inhibitors for Porcine Pancreatic and Human Neutrophil Elastases: A 1.85-Angstroms X-Ray Structure of the Complex between Porcine Pancreatic Elastase and 7-[(N-Tosylphenylalanyl)Amino]-4-Chloro-3-Methoxyisocoumarin</PDBx:title>
         <PDBx:year>1992</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="2">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>Biochemistry</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>BICHAW</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0033</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0006-2960</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>30</PDBx:journal_volume>
         <PDBx:page_first>2175</PDBx:page_first>
         <PDBx:title>Structural Study of Porcine Pancreatic Elastase Complexed with 7-Amino-3-(2-Bromoethoxy)-4-Chloroisocoumarin as a Nonreactivatable Doubly Covalent Enzyme-Inhibitor Complex</PDBx:title>
         <PDBx:year>1991</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="3">
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         <PDBx:journal_volume>112</PDBx:journal_volume>
         <PDBx:page_first>7783</PDBx:page_first>
         <PDBx:title>The 2.2-Angstrom Resolution X-Ray Crystal Structure of the Complex of Trypsin Inhibited by 4-Chloro-3-Ethoxy-7-Guanidinoisocoumarin: A Proposed Model of the Thrombin-Inhibitor Complex</PDBx:title>
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         <PDBx:journal_id_CSD>0033</PDBx:journal_id_CSD>
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         <PDBx:journal_volume>28</PDBx:journal_volume>
         <PDBx:page_first>1951</PDBx:page_first>
         <PDBx:title>Human Leukocyte and Porcine Pancreatic Elastase: X-Ray Crystal Structures, Mechanism, Substrate Specificity, and Mechanism-Based Inhibitors</PDBx:title>
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         <PDBx:journal_volume>198</PDBx:journal_volume>
         <PDBx:page_first>417</PDBx:page_first>
         <PDBx:title>Crystal Structures of the Complex of Porcine Pancreatic Elastase with Two Valine-Derived Benzoxazinone Inhibitors</PDBx:title>
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         <PDBx:journal_volume>107</PDBx:journal_volume>
         <PDBx:page_first>4091</PDBx:page_first>
         <PDBx:title>Stereospecific Reaction of 3-Methoxy-4-Chloro-7-Amino-Isocoumarin with Crystalline Porcine Pancreatic Elastase</PDBx:title>
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         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="159">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="160">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="161">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="162">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="163">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="164">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="165">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="166">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="167">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="168">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="169">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="170">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="171">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="172">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="173">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="174">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="175">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="176">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="177">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="178">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="179">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="180">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="181">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="182">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="183">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="184">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="185">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="186">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="187">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="188">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="189">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="190">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="191">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="192">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="193">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="194">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="195">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="196">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="197">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="198">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="199">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="200">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="201">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="202">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="203">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="204">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="205">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="206">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="207">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="208">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="209">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="210">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="211">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="212">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="213">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="214">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="215">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="216">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="217">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="218">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="219">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="220">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="221">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="222">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="223">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="224">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="225">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="226">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="227">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="228">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="229">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="230">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="231">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="232">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="233">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="234">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="235">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="236">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="237">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="238">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="239">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="240">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_common_name>pig</PDBx:gene_src_common_name>
         <PDBx:gene_src_genus>Sus</PDBx:gene_src_genus>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>9823</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Sus scrofa</PDBx:pdbx_gene_src_scientific_name>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="8EST"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="8EST" method="X-RAY DIFFRACTION">
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>2.14</PDBx:density_Matthews>
         <PDBx:density_percent_sol>42.49</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:pdbx_audit_revision_detailsCategory>
      <PDBx:pdbx_audit_revision_details data_content_type="Structure model" ordinal="1" revision_ordinal="1">
         <PDBx:provider>repository</PDBx:provider>
         <PDBx:type>Initial release</PDBx:type>
      </PDBx:pdbx_audit_revision_details>
   </PDBx:pdbx_audit_revision_detailsCategory>
   <PDBx:pdbx_audit_revision_groupCategory>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="1" revision_ordinal="2">
         <PDBx:group>Version format compliance</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="2" revision_ordinal="3">
         <PDBx:group>Version format compliance</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
   </PDBx:pdbx_audit_revision_groupCategory>
   <PDBx:pdbx_audit_revision_historyCategory>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="1">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>0</PDBx:minor_revision>
         <PDBx:revision_date>1992-10-15</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="2">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>1</PDBx:minor_revision>
         <PDBx:revision_date>2008-03-03</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="3">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>2</PDBx:minor_revision>
         <PDBx:revision_date>2011-07-13</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
   </PDBx:pdbx_audit_revision_historyCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="8EST">
         <PDBx:SG_entry xsi:nil="true" />
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:recvd_initial_deposition_date>1990-02-21</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>SO4</PDBx:comp_id>
         <PDBx:name>SULFATE ION</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>CA</PDBx:comp_id>
         <PDBx:name>CALCIUM ION</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="4">
         <PDBx:comp_id>GIS</PDBx:comp_id>
         <PDBx:name>ETHYL-(2-CARBOXY-4-GUANIDINIUM-PHENYL)-CHLOROACETATE</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="5">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entry_detailsCategory>
      <PDBx:pdbx_entry_details entry_id="8EST">
         <PDBx:compound_details>THIS COMPLEX IS ONE OF THE BEST IRREVERSIBLE INHIBITORS
THUS FAR REPORTED FOR PPE (KOBS/[I] = 8100/(MOLE. SEC) ).</PDBx:compound_details>
         <PDBx:nonpolymer_details>THE TITLE INHIBITOR HAS BEEN STUDIED IN TWO RELATED ENZYMES
PPE AND BOVINE TRYPSIN (REFERENCE 3).  IN THE LATTER CASE,
AS WOULD BE EXPECTED, THE POSITIVELY CHARGED GUANIDINIUM
GROUP IS LOCATED IN TRYPSIN&apos;S PRIMARY SPECIFICITY (S1) SITE
BUT TWO BINDING MODES ARE EXHIBITED, SINGLY AND DOUBLY
COVALENTLY LINKED TO TRYPSIN.  CONVERSELY, THE COMPLEX
PRESENTED IN THIS ENTRY IS FLIPPED APPROXIMATELY 180 DEGREE
SO THAT THE GUANIDINIUM GROUP IS FOUND IN THE S2&apos; SITE,
H-BONDED TO THR E 41.</PDBx:nonpolymer_details>
      </PDBx:pdbx_entry_details>
   </PDBx:pdbx_entry_detailsCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>SO4</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>247</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>SO4</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SO4</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>247</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>CA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>248</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>CA</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>248</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="1">
         <PDBx:auth_mon_id>GIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>269</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>GIS</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>269</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>301</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>302</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>302</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>303</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>303</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>304</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>304</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>305</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>305</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>306</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>306</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>307</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>307</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>308</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>308</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>309</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>309</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>310</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>310</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>311</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>311</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>312</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>312</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>313</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>313</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>314</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>314</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>315</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>315</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>316</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>316</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>317</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>317</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>318</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>318</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>319</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>319</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>320</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>320</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>321</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>321</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>322</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>322</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>323</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>323</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>326</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>326</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>327</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>327</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>328</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>328</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>330</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>330</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>331</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>331</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>332</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>332</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>501</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>502</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>503</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>504</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>504</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>507</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>507</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>508</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>508</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>510</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>510</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>511</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>511</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>512</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>512</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>514</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>514</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>515</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>515</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>516</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>516</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>517</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>517</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>518</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>518</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>519</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>519</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>520</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>520</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>521</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>521</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>523</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>523</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>524</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>524</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>526</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>526</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>527</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>527</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>528</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>528</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>529</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>529</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>530</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>530</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>531</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>531</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>533</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>533</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>534</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>534</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>535</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>535</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>539</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>539</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>540</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>540</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>542</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>542</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>543</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>543</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>544</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>544</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>546</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>546</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>547</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>547</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>548</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>548</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>552</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>552</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>555</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>555</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>557</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>557</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>562</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>562</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>564</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>564</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>566</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>566</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>570</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>570</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>572</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>572</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>573</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>573</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>575</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>575</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>578</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>578</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>579</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>579</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>580</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>580</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>581</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>581</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>583</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>583</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>587</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>587</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>588</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>588</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>596</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>596</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>605</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>605</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>610</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>610</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>616</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>616</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>618</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>618</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>620</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>620</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>628</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>628</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>629</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>629</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>630</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>630</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>631</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>631</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>632</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>632</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>633</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>633</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>634</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>634</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>635</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>635</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>636</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>636</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>637</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>637</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>638</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>638</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>639</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>639</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>641</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>641</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>642</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>642</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>643</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>643</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="111">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>644</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>644</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="112">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>646</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>646</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="113">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>647</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>647</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="114">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>648</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>648</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="115">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>649</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>649</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="116">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>650</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>650</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="117">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>651</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>651</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="118">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>652</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>652</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="119">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>653</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>653</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="120">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>654</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>654</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="121">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>655</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>655</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="122">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>656</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>656</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="123">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>657</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>657</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="124">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>658</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>658</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="125">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>659</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>659</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="126">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>660</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>660</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="127">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>661</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>661</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="128">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>662</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>662</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="129">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>663</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>663</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="130">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>664</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>664</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="131">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>665</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>665</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="132">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>666</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>666</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="133">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>667</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>667</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="134">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>668</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>668</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="135">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>669</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>669</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="136">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>670</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>670</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="137">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>671</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>671</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="138">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>672</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>672</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="139">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>673</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>673</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="140">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>675</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>675</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="141">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>676</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>676</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="142">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>677</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>677</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="143">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>678</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>678</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="144">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>679</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>679</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="145">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>680</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>680</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="146">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>681</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>681</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="147">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>682</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>682</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="148">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>683</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>683</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="149">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>684</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>684</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="150">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>685</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>685</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="151">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>686</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>686</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="152">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>687</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>687</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="153">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>688</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>688</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="154">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>689</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>689</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="155">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>690</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>690</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="156">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>691</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>691</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="157">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>692</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>692</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="158">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>693</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>693</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="159">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>694</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>694</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="160">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>695</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>695</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="161">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>696</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>696</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="162">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>697</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>697</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="163">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>698</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>698</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="164">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>699</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>699</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="165">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>700</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>700</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="166">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>701</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>701</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="167">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>702</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>702</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="168">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>703</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>703</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="169">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>706</PDBx:auth_seq_num>
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>706</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="1">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>16</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="2">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>17</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>17</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="3">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>18</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>18</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="4">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>19</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>19</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="5">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>20</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>20</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="6">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>21</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>21</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="7">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>22</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>22</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="8">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>23</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>23</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="9">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>24</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>24</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="10">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>25</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>25</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="11">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>26</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>26</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="12">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>27</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>27</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="13">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>28</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>28</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="14">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>29</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>29</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="15">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>30</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>30</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="16">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>31</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>31</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="17">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>32</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>32</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="18">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>33</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>33</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="19">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>34</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>34</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="20">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>35</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>35</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="21">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>36</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="22">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>A</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>36</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="23">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>B</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>36</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="24">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>C</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>36</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="25">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>37</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>37</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="26">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>38</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>38</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="27">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>39</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>39</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="28">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>40</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>40</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="29">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>41</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>41</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="30">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>42</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>42</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="31">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>43</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>43</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="32">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>44</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>44</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="33">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>45</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>45</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="34">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>46</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>46</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="35">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>47</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>47</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="36">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>48</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>48</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="37">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>49</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>49</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="38">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>50</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>50</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="39">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>51</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>51</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="40">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>52</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>52</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="41">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>53</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>53</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="42">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>54</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>54</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="43">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>55</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>55</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="44">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>56</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>56</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="45">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>57</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>57</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="46">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>58</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>58</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="47">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>59</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>59</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="48">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>60</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>60</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="49">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>61</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>61</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="50">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>62</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>62</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="51">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>63</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>63</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="52">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>64</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>64</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="53">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>65</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>65</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="54">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>65</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>A</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>65</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="55">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>66</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>66</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="56">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>67</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>67</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="57">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>68</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>68</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="58">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>69</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>69</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="59">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>70</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>70</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="60">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>71</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>71</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="61">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>72</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>72</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="62">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>73</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>73</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="63">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>74</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>74</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="64">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>75</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>75</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="65">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>76</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>76</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="66">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>77</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>77</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="67">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>78</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>78</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="68">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>79</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>79</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="69">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>80</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>80</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="70">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>81</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>81</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="71">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>82</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>82</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="72">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>83</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>83</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="73">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>84</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>84</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="74">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>85</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>85</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="75">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>86</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>86</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="76">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>87</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>87</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="77">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>88</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>88</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="78">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>89</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>89</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="79">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>90</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>90</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="80">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>91</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>91</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="81">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>92</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>92</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="82">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>93</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>93</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="83">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>94</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>94</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="84">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>95</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>95</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="85">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>96</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>96</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="86">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>97</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>97</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="87">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>98</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>98</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="88">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>99</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>99</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="89">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>99</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>A</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>99</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="90">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>99</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>B</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>99</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="91">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>100</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>100</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="92">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>101</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="93">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>102</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>102</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="94">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>103</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>103</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="95">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>104</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>104</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="96">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>105</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>105</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="97">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>106</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>106</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="98">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>107</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>107</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="99">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>108</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>108</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="100">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>109</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>109</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="101">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>110</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>110</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="102">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>111</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>111</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="103">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>112</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>112</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="104">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>113</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>113</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="105">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>114</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>114</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="106">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>115</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>115</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="107">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>116</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>116</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="108">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>117</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>117</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="109">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>118</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>118</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="110">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>119</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>119</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="111">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>120</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>120</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="112">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>121</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>121</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="113">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>122</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>122</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="114">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>123</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>123</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="115">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>124</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>124</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="116">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>125</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>125</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="117">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>126</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>126</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="118">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>127</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>127</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="119">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>128</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>128</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="120">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>129</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>129</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="121">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>130</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>130</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="122">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>131</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>131</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="123">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>132</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>132</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="124">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>133</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>133</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="125">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>134</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>134</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="126">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>135</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>135</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="127">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>136</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>136</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="128">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>137</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>137</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="129">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>138</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>138</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="130">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>139</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>139</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="131">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>140</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>140</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="132">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>141</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>141</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="133">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>142</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>142</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="134">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>143</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>143</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="135">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>144</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>144</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="136">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>145</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>145</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="137">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>147</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>147</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="138">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>148</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>148</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="139">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>149</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>149</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="140">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>150</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>150</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="141">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>151</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>151</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="142">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>152</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>152</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="143">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>153</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>153</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="144">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>154</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>154</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="145">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>155</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>155</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="146">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>156</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>156</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="147">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>157</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>157</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="148">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>158</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>158</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="149">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>159</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>159</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="150">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>160</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>160</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="151">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>161</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>161</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="152">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>162</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>162</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="153">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>163</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>163</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="154">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>164</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>164</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="155">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>165</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>165</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="156">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>166</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>166</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="157">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>167</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>167</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="158">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>168</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>168</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="159">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>169</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>169</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="160">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>170</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>170</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="161">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>170</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>A</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>170</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="162">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>170</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>B</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>170</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="163">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>171</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>171</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="164">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>172</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>172</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="165">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>173</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>173</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="166">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>174</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>174</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="167">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>175</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>175</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="168">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>176</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>176</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="169">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>177</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>177</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="170">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>178</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>178</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="171">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>179</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>179</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="172">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>180</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>180</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="173">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>181</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>181</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="174">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>182</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>182</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="175">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>183</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>183</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="176">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>184</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>184</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="177">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>185</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>185</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="178">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>186</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>186</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="179">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>187</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>187</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="180">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>188</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>188</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="181">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>188</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>A</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>188</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="182">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>189</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>189</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="183">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>190</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>190</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="184">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>191</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>191</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="185">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>192</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>192</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="186">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>193</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>193</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="187">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>194</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>194</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="188">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>195</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>195</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="189">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>196</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>196</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="190">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>197</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>197</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="191">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>198</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>198</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="192">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>199</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>192</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>199</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="193">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>200</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>193</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>200</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="194">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>201</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>194</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>201</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="195">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>202</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>195</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>202</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="196">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>203</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>203</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="197">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>204</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>204</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="198">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>205</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>198</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>205</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="199">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>206</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>199</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>206</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="200">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>207</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>200</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>207</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="201">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>208</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>201</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>208</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="202">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>209</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>202</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>209</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="203">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>210</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>203</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>210</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="204">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>211</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>204</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>211</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="205">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>212</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>205</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>212</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="206">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>213</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>206</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>213</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="207">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>214</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>207</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>214</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="208">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>215</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>208</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>215</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="209">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>216</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>209</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>216</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="210">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>217</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>210</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="211">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>217</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>211</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>A</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="212">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>218</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>212</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>218</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="213">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>219</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>213</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>219</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="214">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>220</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>214</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>220</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="215">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>221</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>215</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="216">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>221</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>216</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code>A</PDBx:pdb_ins_code>
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="217">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>222</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>217</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>222</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="218">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>223</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>218</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>223</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="219">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>224</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>219</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>224</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="220">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>225</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>220</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>225</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="221">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>226</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>221</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>226</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="222">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>227</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>222</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>227</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="223">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>228</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>223</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>228</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="224">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>229</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>224</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>229</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="225">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>230</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>225</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>230</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="226">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>231</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>226</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>231</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="227">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>232</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>227</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>232</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="228">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>233</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>228</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>233</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="229">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>234</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>229</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>234</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="230">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>235</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>230</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>235</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="231">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>236</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>231</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>236</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="232">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>237</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>232</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>237</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="233">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>238</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>233</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>238</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="234">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>239</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>234</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>239</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="235">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>240</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>235</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>240</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="236">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>241</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>236</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>241</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="237">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>242</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>237</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>242</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="238">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>243</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>238</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>243</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="239">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>244</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>239</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>244</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="240">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>245</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>240</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>245</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>E</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_and_software_defined_assembly</PDBx:details>
         <PDBx:method_details>PISA</PDBx:method_details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D,E" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_conn_angleCategory>
      <PDBx:pdbx_struct_conn_angle id="1">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLU</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>70</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OE1</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLU</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>59</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>ASN</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>72</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>ASN</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>61</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>80.1</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="2">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLU</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>70</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OE1</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLU</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>59</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>GLN</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>75</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>GLN</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>64</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>154.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="3">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>ASN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>72</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>ASN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>61</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>GLN</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>75</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>GLN</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>64</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>77.3</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="4">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLU</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>70</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OE1</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLU</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>59</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>GLU</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>80</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>OE2</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>GLU</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>69</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>106.2</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="5">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>ASN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>72</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>ASN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>61</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>GLU</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>80</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>OE2</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>GLU</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>69</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>169.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="6">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>75</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>64</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>GLU</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>80</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>OE2</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>GLU</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>69</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>94.7</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="7">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLU</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>70</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OE1</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLU</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>59</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>ASN</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>77</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>OD1</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>ASN</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>66</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>80.3</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="8">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>ASN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>72</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>ASN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>61</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>ASN</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>77</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>OD1</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>ASN</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>66</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>90.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="9">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>75</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>64</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>ASN</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>77</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>OD1</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>ASN</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>66</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>110.9</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="10">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLU</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>80</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OE2</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLU</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>69</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>ASN</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>77</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>OD1</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>ASN</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>66</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>98.1</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="11">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLU</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>70</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OE1</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLU</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>59</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>327</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>87.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="12">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>ASN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>72</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>ASN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>61</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>327</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>90.5</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="13">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>75</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>64</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>327</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>81.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="14">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>GLU</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>80</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OE2</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>GLU</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>69</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>327</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>81.9</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="15">
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>ASN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>77</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OD1</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>ASN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>66</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CA</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>248</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CA</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CA</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>E</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>327</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>167.6</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
   </PDBx:pdbx_struct_conn_angleCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_validate_main_chain_planeCategory>
      <PDBx:pdbx_validate_main_chain_plane id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>42</PDBx:auth_seq_id>
         <PDBx:improper_torsion_angle>-14.80</PDBx:improper_torsion_angle>
      </PDBx:pdbx_validate_main_chain_plane>
      <PDBx:pdbx_validate_main_chain_plane id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>189</PDBx:auth_seq_id>
         <PDBx:improper_torsion_angle>-10.52</PDBx:improper_torsion_angle>
      </PDBx:pdbx_validate_main_chain_plane>
      <PDBx:pdbx_validate_main_chain_plane id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>195</PDBx:auth_seq_id>
         <PDBx:improper_torsion_angle>10.20</PDBx:improper_torsion_angle>
      </PDBx:pdbx_validate_main_chain_plane>
   </PDBx:pdbx_validate_main_chain_planeCategory>
   <PDBx:pdbx_validate_planesCategory>
      <PDBx:pdbx_validate_planes id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>21</PDBx:auth_seq_id>
         <PDBx:rmsd>0.070</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>70</PDBx:auth_seq_id>
         <PDBx:rmsd>0.070</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>74</PDBx:auth_seq_id>
         <PDBx:rmsd>0.086</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>178</PDBx:auth_seq_id>
         <PDBx:rmsd>0.076</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>192</PDBx:auth_seq_id>
         <PDBx:rmsd>0.071</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>194</PDBx:auth_seq_id>
         <PDBx:rmsd>0.086</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>234</PDBx:auth_seq_id>
         <PDBx:rmsd>0.077</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
   </PDBx:pdbx_validate_planesCategory>
   <PDBx:pdbx_validate_rmsd_angleCategory>
      <PDBx:pdbx_validate_rmsd_angle id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>3.42</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>123.72</PDBx:angle_value>
         <PDBx:auth_asym_id_1>E</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>E</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>E</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>107</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>107</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="2">
         <PDBx:PDB_ins_code_1>A</PDBx:PDB_ins_code_1>
         <PDBx:PDB_ins_code_2>A</PDBx:PDB_ins_code_2>
         <PDBx:PDB_ins_code_3>A</PDBx:PDB_ins_code_3>
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-3.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>116.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>E</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>E</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>E</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>188</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>188</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>188</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
   </PDBx:pdbx_validate_rmsd_angleCategory>
   <PDBx:pdbx_validate_rmsd_bondCategory>
      <PDBx:pdbx_validate_rmsd_bond id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>E</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>E</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>107</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>0.078</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.013</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.326</PDBx:bond_target_value>
         <PDBx:bond_value>1.404</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
   </PDBx:pdbx_validate_rmsd_bondCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>27</PDBx:auth_seq_id>
         <PDBx:phi>-116.61</PDBx:phi>
         <PDBx:psi>60.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>171</PDBx:auth_seq_id>
         <PDBx:phi>-91.12</PDBx:phi>
         <PDBx:psi>-122.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="8EST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:details>THE FOLLOWING ATOMS WERE TREATED AS DUMMY ATOMS, WHICH MEANS THAT THEY CONTRIBUTED TO THE ENERGY REFINEMENT PART OF EREF BUT NOT TO THE CALCULATED STRUCTURE FACTORS -SER 36C OG, SER 37 OG, ARG 61 (CZ,NH1,NH2), GLN 110 (CG,CD,OE1,NE2), ARG 125 (CG,CD,NE,CZ,NH1,NH2), SO4 247 (O1,O3).</PDBx:details>
         <PDBx:ls_R_factor_R_work>0.17</PDBx:ls_R_factor_R_work>
         <PDBx:ls_d_res_high>1.78</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>7.0</PDBx:ls_d_res_low>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.78</PDBx:d_res_high>
         <PDBx:d_res_low>7.0</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>169</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>2016</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>25</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>1822</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_bond_d">
         <PDBx:dev_ideal>0.015</PDBx:dev_ideal>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_bond_d_na">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_bond_d_prot">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_angle_d">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_angle_d_na">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_angle_d_prot">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_angle_deg">
         <PDBx:dev_ideal>2.0</PDBx:dev_ideal>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_angle_deg_na">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_angle_deg_prot">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_dihedral_angle_d">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_dihedral_angle_d_na">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_dihedral_angle_d_prot">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_improper_angle_d">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_improper_angle_d_na">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_improper_angle_d_prot">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_mcbond_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_mcangle_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_scbond_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="o_scangle_it">
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>EREF</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="8EST">
         <PDBx:pdbx_descriptor>PORCINE PANCREATIC ELASTASE (E.C.3.4.21.11) COMPLEX WITH GUANIDINIUM ISOCOUMARIN</PDBx:pdbx_descriptor>
         <PDBx:title>REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="E">
         <PDBx:entity_id>5</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1"></PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>164</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>154</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>170</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>160</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>HA</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>7</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>TYR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>234</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>TYR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>229</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:details>HELICAL TAIL AT CARBOXY END</PDBx:details>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>245</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>240</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>HB</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>12</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_connCategory>
      <PDBx:struct_conn id="disulf1">
         <PDBx:conn_type_id>disulf</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.062</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>42</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>30</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CYS</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>58</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>SG</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CYS</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>46</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="disulf2">
         <PDBx:conn_type_id>disulf</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.047</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>136</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>127</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CYS</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>201</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>SG</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CYS</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>194</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="disulf3">
         <PDBx:conn_type_id>disulf</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.027</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>168</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>158</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CYS</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>182</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>SG</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CYS</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>174</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="disulf4">
         <PDBx:conn_type_id>disulf</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.060</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>191</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>184</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CYS</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>220</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>SG</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CYS</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>214</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="covale1">
         <PDBx:conn_type_id>covale</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>1.363</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>SER</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>195</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>OG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>SER</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>188</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>GIS</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>269</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>C1</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>GIS</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc1">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.390</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CA</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>248</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CA</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CA</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>GLU</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>70</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>OE1</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>GLU</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>59</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc2">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.424</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CA</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>248</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CA</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CA</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ASN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>72</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ASN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>61</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc3">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.308</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CA</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>248</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CA</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CA</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>GLN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>75</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>GLN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>64</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc4">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.322</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CA</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>248</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CA</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CA</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>GLU</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>80</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>OE2</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>GLU</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>69</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc5">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.446</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CA</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>248</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CA</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CA</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ASN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>77</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>OD1</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ASN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>66</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc6">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.441</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>E</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CA</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>248</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CA</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CA</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>E</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>327</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
   </PDBx:struct_connCategory>
   <PDBx:struct_conn_typeCategory>
      <PDBx:struct_conn_type id="disulf">
      </PDBx:struct_conn_type>
      <PDBx:struct_conn_type id="covale">
      </PDBx:struct_conn_type>
      <PDBx:struct_conn_type id="metalc">
      </PDBx:struct_conn_type>
   </PDBx:struct_conn_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="8EST">
         <PDBx:pdbx_keywords>HYDROLASE(SERINE PROTEINASE)</PDBx:pdbx_keywords>
         <PDBx:text>HYDROLASE(SERINE PROTEINASE)</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>ELA1_PIG</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>1</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P00772</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>MLRLLVVASLVLYGHSTQDFPETNARVVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFR
VVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTILANNSPCYITGWGL
TRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGC
NVTRKPTVFTRVSAYISWINNVIASN</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>27</PDBx:db_align_beg>
         <PDBx:db_align_end>266</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>8EST</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>16</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>245</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P00772</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>E</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>240</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>ASP</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>ASN</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>77</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>8EST</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>E</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00772</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>92</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>66</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="A">
         <PDBx:number_strands>7</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="B">
         <PDBx:number_strands>7</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="C">
         <PDBx:number_strands>3</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="4" range_id_2="5" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="5" range_id_2="6" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="6" range_id_2="7" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="4" range_id_2="5" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="5" range_id_2="6" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="6" range_id_2="7" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="C">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="C">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="A">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>29</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>14</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>36</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>22</PDBx:end_label_seq_id>
         <PDBx:pdbx_end_PDB_ins_code>A</PDBx:pdbx_end_PDB_ins_code>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="A">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>37</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>25</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>47</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>35</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="A">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>50</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>38</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>56</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>44</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="A">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>102</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>93</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>110</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>101</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="5" sheet_id="A">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>80</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>69</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>HIS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>91</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>HIS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>80</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="6" sheet_id="A">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PHE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>65</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PHE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>53</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>69</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>58</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="7" sheet_id="A">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>29</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>14</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>36</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>22</PDBx:end_label_seq_id>
         <PDBx:pdbx_end_PDB_ins_code>A</PDBx:pdbx_end_PDB_ins_code>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="B">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>133</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>124</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>THR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>144</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>THR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>135</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="B">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>149</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>139</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>163</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>153</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="B">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>179</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>171</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>188</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>180</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="B">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>221</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>215</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>231</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>226</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="5" sheet_id="B">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>210</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>203</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>216</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>209</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="6" sheet_id="B">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>195</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>188</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>CYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>201</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>CYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>194</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="7" sheet_id="B">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>133</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>124</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>THR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>144</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>THR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>135</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="C">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>149</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>139</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>152</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>142</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="C">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>TRP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>141</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>TRP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>132</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>143</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>134</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="C">
         <PDBx:beg_auth_asym_id>E</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>192</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>185</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>E</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>194</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>187</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="CAT">
         <PDBx:details>catalytic site</PDBx:details>
         <PDBx:pdbx_evidence_code>Author</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>4</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC1">
         <PDBx:details>BINDING SITE FOR RESIDUE SO4 E 247</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>7</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>BINDING SITE FOR RESIDUE CA E 248</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>6</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC3">
         <PDBx:details>BINDING SITE FOR RESIDUE GIS E 269</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>11</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="CAT">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>57</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>45</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="CAT">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>102</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="CAT">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>195</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="CAT">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>214</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>207</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>127</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>118</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>136</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>2_465</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>230</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>225</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>232</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>227</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>233</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>228</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>2_465</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC1">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>579</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC2">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>70</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>59</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC2">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>72</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>61</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC2">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>75</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_seq_id>64</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC2">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>77</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>66</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC2">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>80</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>69</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="17" site_id="AC2">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>327</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="18" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>41</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_seq_id>29</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="19" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>42</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>30</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="20" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>55</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>43</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="21" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>57</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>45</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="22" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>58</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>46</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="23" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>191</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>184</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="24" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>192</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_seq_id>185</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="25" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>195</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="26" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>196</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>189</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="27" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>214</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>207</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="28" site_id="AC3">
         <PDBx:auth_asym_id>E</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>628</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>11</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="8EST">
         <PDBx:Int_Tables_number>19</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 21 21 21</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
