@@ -1,5 +1,5 @@
 <?xml version="1.0" encoding="UTF-8" standalone="yes"?>
-<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" version="1.2; October 1, 2013">
+<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" version="1.3; February 11, 2014">
   <xs:element name="ReleaseSet" type="ReleaseType"/>
   <xs:element name="ClinVarSet" type="PublicSetType">
     <xs:annotation>
@@ -410,7 +410,7 @@
                 </xs:sequence>
               </xs:complexType>
             </xs:element>
-            <xs:element maxOccurs="1" minOccurs="0" name="CytogeneticLocation" type="xs:string">
+            <xs:element maxOccurs="2" minOccurs="0" name="CytogeneticLocation" type="xs:string">
               <xs:annotation>
                 <xs:documentation>Cytogenetic location is maintained independent of sequence location.</xs:documentation>
               </xs:annotation>
@@ -482,9 +482,11 @@
                 <xs:enumeration value="Structural variant"/>
                 <xs:enumeration value="copy number gain"/>
                 <xs:enumeration value="copy number loss"/>
+                <xs:enumeration value="protein only"/>
                 <xs:enumeration value="Microsatellite"/>
                 <xs:enumeration value="fusion"/>
                 <xs:enumeration value="inversion"/>
+                <xs:enumeration value="QTL"/>
               </xs:restriction>
             </xs:simpleType>
           </xs:attribute>
@@ -781,7 +783,7 @@
                 <xs:element maxOccurs="1" minOccurs="0" name="Type">
                   <xs:simpleType>
                     <xs:restriction base="xs:string">
-                      <xs:enumeration value="curation"/>
+                      <xs:enumeration value="literature only"/>
                       <xs:enumeration value="reference population"/>
                       <xs:enumeration value="case-control"/>
                       <xs:enumeration value="clinical testing"/>
@@ -814,7 +816,7 @@
                           <xs:enumeration value="VariantAlleles"/>
                           <xs:enumeration value="SubjectsWithVariant"/>
                           <xs:enumeration value="SubjectsWithDifferentCausativeVariant"/>
-                          <xs:enumeration value="SubjectsOnlyVariant"/>
+                          <xs:enumeration value="VariantChromosomes"/>
                           <xs:enumeration value="IndependentObservations"/>
                           <xs:enumeration value="SingleHeterozygote"/>
                           <xs:enumeration value="CompoundHeterozygote"/>
@@ -1043,6 +1045,9 @@
     </xs:sequence>
   </xs:complexType>
   <xs:simpleType name="ReviewStatusType">
+    <xs:annotation>
+      <xs:documentation>The values of review status are used to build the 'star ratings' displayed on the ClinVar public site. 0 stars: a conflict or not classified by submitter 1 star: classified by single submitter 2 stars: classified by multiple submitters 3 stars: reviewed by expert panel 4 stars: reviewed by professional society</xs:documentation>
+    </xs:annotation>
     <xs:restriction base="xs:string">
       <xs:enumeration value="not classified by submitter"/>
       <xs:enumeration value="classified by single submitter"/>
@@ -1104,6 +1109,7 @@
   <xs:simpleType name="Methodtypelist">
     <xs:restriction base="xs:string">
       <xs:enumeration value="curation"/>
+      <xs:enumeration value="literature only"/>
       <xs:enumeration value="reference population"/>
       <xs:enumeration value="case-control"/>
       <xs:enumeration value="clinical testing"/>