#BioGRID Chemical Interaction ID	BioGRID Gene ID	Entrez Gene ID	Systematic Name	Official Symbol	Synonyms	Organism ID	Organism	Action	Interaction Type	Author	Pubmed ID	BioGRID Publication ID	BioGRID Chemical ID	Chemical Name	Chemical Synonyms	Chemical Brands	Chemical Source	Chemical Source ID	Molecular Formula	Chemical Type	ATC Codes	CAS Number	Curated By	Method	Method Description	Related BioGRID Gene ID	Related Entrez Gene ID	Related Systematic Name	Related Official Symbol	Related Synonyms	Related Organism ID	Related Organism	Related Type	Notes	InChIKey
11	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
12	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Zhang W (2007)	17704420	171743	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
13	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
52	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Hughes LB (2004)	15526004	171758	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
53	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Criswell LA (2004)	15457442	171757	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
309	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	antagonist	target	Siberil S (2007)	17911465	171892	28	Immune Globulin Human	Immune Globulin Subcutaneous|Human Normal Immunoglobulin|Immune Globulin Intravenous|IVIg|Human IGG|Immunoglobulin G (human)|Human Immunoglobulin G|Immune globulin (human)|Intravenous Immunoglobulin|Immunoglobulin G, Human	gamastan s/d|octagam 10%|immun	DRUGBANK	DB00028	C6332H9826N1692O1980S42	biologic	-	9007-83-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
310	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	antagonist	target	Baerenwaldt A (2010)	20441428	171893	28	Immune Globulin Human	Immune Globulin Subcutaneous|Human Normal Immunoglobulin|Immune Globulin Intravenous|IVIg|Human IGG|Immunoglobulin G (human)|Human Immunoglobulin G|Immune globulin (human)|Intravenous Immunoglobulin|Immunoglobulin G, Human	gamastan s/d|octagam 10%|immun	DRUGBANK	DB00028	C6332H9826N1692O1980S42	biologic	-	9007-83-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
311	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	antagonist	target	Negi VS (2007)	17351760	171891	28	Immune Globulin Human	Immune Globulin Subcutaneous|Human Normal Immunoglobulin|Immune Globulin Intravenous|IVIg|Human IGG|Immunoglobulin G (human)|Human Immunoglobulin G|Immune globulin (human)|Intravenous Immunoglobulin|Immunoglobulin G, Human	gamastan s/d|octagam 10%|immun	DRUGBANK	DB00028	C6332H9826N1692O1980S42	biologic	-	9007-83-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
360	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
361	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
599	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
600	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
637	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	53	Abciximab	7E3|7E3 antibody|antiGPIIBIIIa|C7E3	reopro	DRUGBANK	DB00054	C6462H9964N1690O2049S48	biologic	B01AC13	143653-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
638	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	53	Abciximab	7E3|7E3 antibody|antiGPIIBIIIa|C7E3	reopro	DRUGBANK	DB00054	C6462H9964N1690O2049S48	biologic	B01AC13	143653-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
713	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	55	Gemtuzumab ozogamicin	-	-	DRUGBANK	DB00056	-	biologic	-	220578-59-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
714	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	55	Gemtuzumab ozogamicin	-	-	DRUGBANK	DB00056	-	biologic	-	220578-59-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
750	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Mojzisova H (2007)	17141733	172116	61	Human Serum Albumin	Human albumin|Albumin human|Albumin microspheres, human|Albumin (human)|Albumin, human|Albumin, blood|Serum albumin	sterile diluent for allergenic	DRUGBANK	DB00062	C2936H4624N786O889S41	biologic	-	9048-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
751	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Michaelis K (2006)	16554356	172114	61	Human Serum Albumin	Human albumin|Albumin human|Albumin microspheres, human|Albumin (human)|Albumin, human|Albumin, blood|Serum albumin	sterile diluent for allergenic	DRUGBANK	DB00062	C2936H4624N786O889S41	biologic	-	9048-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
752	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Yuan Z (2003)	12860569	172115	61	Human Serum Albumin	Human albumin|Albumin human|Albumin microspheres, human|Albumin (human)|Albumin, human|Albumin, blood|Serum albumin	sterile diluent for allergenic	DRUGBANK	DB00062	C2936H4624N786O889S41	biologic	-	9048-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
753	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Yuan ZY (2003)	12887764	172112	61	Human Serum Albumin	Human albumin|Albumin human|Albumin microspheres, human|Albumin (human)|Albumin, human|Albumin, blood|Serum albumin	sterile diluent for allergenic	DRUGBANK	DB00062	C2936H4624N786O889S41	biologic	-	9048-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
754	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Yamashita T (2007)	17553935	172113	61	Human Serum Albumin	Human albumin|Albumin human|Albumin microspheres, human|Albumin (human)|Albumin, human|Albumin, blood|Serum albumin	sterile diluent for allergenic	DRUGBANK	DB00062	C2936H4624N786O889S41	biologic	-	9048-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
764	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Wang L (2006)	17378158	172130	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
765	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
766	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
767	106845	348	-	APOE	AD2|APO-E|LDLCQ5|LPG	9606	Homo sapiens	unknown	target	Cano NJ (2006)	16441928	172131	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
834	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
835	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Authier F (2002)	11779865	172178	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
836	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
837	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Nunn SE (1997)	9130467	172177	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
838	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Ogino S (1999)	10229502	172179	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
867	109364	3119	DADB-249P12.2	HLA-DQB1	CELIAC1|HLA-DQB|IDDM1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
868	109364	3119	DADB-249P12.2	HLA-DQB1	CELIAC1|HLA-DQB|IDDM1	9606	Homo sapiens	unknown	target	Levy-Marchal C (1992)	1612232	172194	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
869	109364	3119	DADB-249P12.2	HLA-DQB1	CELIAC1|HLA-DQB|IDDM1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
870	109364	3119	DADB-249P12.2	HLA-DQB1	CELIAC1|HLA-DQB|IDDM1	9606	Homo sapiens	unknown	target	Mahran MZ (1992)	1728861	172193	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
871	109364	3119	DADB-249P12.2	HLA-DQB1	CELIAC1|HLA-DQB|IDDM1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
906	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	71	Trastuzumab	Anti HER2|Ig gamma-1 chain C region	herceptin|perjeta-herceptin	DRUGBANK	DB00072	C6470H10012N1726O2013S42	biologic	L01XC03	180288-69-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
907	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Zhang W (2007)	17704420	171743	71	Trastuzumab	Anti HER2|Ig gamma-1 chain C region	herceptin|perjeta-herceptin	DRUGBANK	DB00072	C6470H10012N1726O2013S42	biologic	L01XC03	180288-69-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
908	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	71	Trastuzumab	Anti HER2|Ig gamma-1 chain C region	herceptin|perjeta-herceptin	DRUGBANK	DB00072	C6470H10012N1726O2013S42	biologic	L01XC03	180288-69-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
917	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Hatjiharissi E (2007)	17324336	172213	72	Rituximab	Ig gamma-1 chain C region|AntiCD20	rituxan sc|rituxan	DRUGBANK	DB00073	C6416H9874N1688O1987S44	biologic	L01XC02	174722-31-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
918	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Kim DH (2006)	16609067	172212	72	Rituximab	Ig gamma-1 chain C region|AntiCD20	rituxan sc|rituxan	DRUGBANK	DB00073	C6416H9874N1688O1987S44	biologic	L01XC02	174722-31-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
944	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
945	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
980	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	74	Muromonab	Anti-CD3|Muromonab-CD3	okt3|orthoclone okt 3 sterile 	DRUGBANK	DB00075	C6460H9946N1720O2043S56	biologic	L04AA02	140608-64-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
981	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	74	Muromonab	Anti-CD3|Muromonab-CD3	okt3|orthoclone okt 3 sterile 	DRUGBANK	DB00075	C6460H9946N1720O2043S56	biologic	L04AA02	140608-64-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1011	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	76	Ibritumomab tiuxetan	mAb Murine (IGG1) Anti P19437 (CD20_MOUSE)|Ibritumomab	zevalin	DRUGBANK	DB00078	C6382H9830N1672O1979S54	biologic	-	206181-63-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1012	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	76	Ibritumomab tiuxetan	mAb Murine (IGG1) Anti P19437 (CD20_MOUSE)|Ibritumomab	zevalin	DRUGBANK	DB00078	C6382H9830N1672O1979S54	biologic	-	206181-63-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1038	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	78	Tositumomab	Ig gamma-1 chain C region	bexxar therapy	DRUGBANK	DB00081	C6416H9874N1688O1987S44	biologic	-	208921-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1039	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	78	Tositumomab	Ig gamma-1 chain C region	bexxar therapy	DRUGBANK	DB00081	C6416H9874N1688O1987S44	biologic	-	208921-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1083	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Lin TS (2005)	15217834	172272	83	Alemtuzumab	-	mabcampath|lemtrada|campath	DRUGBANK	DB00087	C6468H10066N1732O2005S40	biologic	L04AA34	216503-57-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1137	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	88	Alefacept	ASP0485	amevive	DRUGBANK	DB00092	C2306H3594N610O694S26	biologic	L04AA15	222535-22-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1138	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	88	Alefacept	ASP0485	amevive	DRUGBANK	DB00092	C2306H3594N610O694S26	biologic	L04AA15	222535-22-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1169	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	91	Efalizumab	antiCD11 alpha|anti alphaL integrin|hu1124|Raptiva	raptiva	DRUGBANK	DB00095	-	biologic	L04AA21	214745-43-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1170	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	91	Efalizumab	antiCD11 alpha|anti alphaL integrin|hu1124|Raptiva	raptiva	DRUGBANK	DB00095	-	biologic	L04AA21	214745-43-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1292	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	103	Natalizumab	Anti-alpha4 integrin|Anti-VLA4	tysabri	DRUGBANK	DB00108	-	biologic	L04AA23	189261-10-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1293	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	103	Natalizumab	Anti-alpha4 integrin|Anti-VLA4	tysabri	DRUGBANK	DB00108	-	biologic	L04AA23	189261-10-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1316	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	105	Palivizumab	anti-RSV|Synagis	synagis	DRUGBANK	DB00110	-	biologic	J06BB16	188039-54-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1317	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	105	Palivizumab	anti-RSV|Synagis	synagis	DRUGBANK	DB00110	-	biologic	J06BB16	188039-54-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1338	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1339	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1373	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	107	Bevacizumab	antiVEGF|Avastin	avastin	DRUGBANK	DB00112	C6538H10034N1716O2033S44	biologic	L01XC07	216974-75-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1374	108506	2212	RP11-5K23.6	FCGR2A	CD32|CD32A|CDw32|FCG2|FCGR2|FCGR2A1|FcGR|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	107	Bevacizumab	antiVEGF|Avastin	avastin	DRUGBANK	DB00112	C6538H10034N1716O2033S44	biologic	L01XC07	216974-75-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1434	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Rahman MK (1982)	6983619	172488	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1435	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Allen GF (2010)	20403077	172489	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1436	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Overington JP (2006)	17139284	171741	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1437	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Rorsman F (1995)	7567987	172491	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1438	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Bertoldi M (2000)	11085948	172490	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1439	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Imming P (2006)	17016423	171742	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1562	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Skoeldberg F (2004)	15070923	172526	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1563	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Skoeldberg F (2003)	12679420	172563	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1564	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Yee RE (2001)	11709201	172562	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1565	108011	1644	-	DDC	AADC	9606	Homo sapiens	cofactor	target	Tan EK (2005)	15965967	172561	109	Pyridoxal Phosphate	Pyridoxal 5-monophosphoric acid ester|PLP|Pyridoxal phosphate anhydrous|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde|Pyridoxal 5-phosphate|Pyridoxal-P|Pyridoxal 5'-phosphate|Pyridoxal P|Codecarboxylase|Pyridoxal-5P|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	-	DRUGBANK	DB00114	C8H10NO6P	small molecule	A11HA06	54-47-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGVDGCNFYWLIFO-UHFFFAOYSA-N
1799	121249	56922	-	MCCC1	MCC-B|MCCA	9606	Homo sapiens	unknown	target	Friebel D (2006)	16773504	172752	116	Biotin	Biotinum|Vitamin H|(3AS,4S,6ar)-hexahydro-2-oxo-1H-thieno[3,4-D]imidazole-4-valeric acid|cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid|cis-Tetrahydro-2-oxothieno(3,4-D)imidazoline-4-valeric acid|(+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid|Vitamin B7|Coenzyme R|D(+)-Biotin|Biotin|D-(+)-Biotin|5-(2-Oxohexahydro-1H-thieno[3,4-D]imidazol-4-yl)pentanoic acid|D-Biotin|Biotine|cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid|Biotina	balanced b 125 srt|nata komple	DRUGBANK	DB00121	C10H16N2O3S	small molecule	A11HA05	58-85-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBJHBAHKTGYVGT-ZKWXMUAHSA-N
1930	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Floryszak-Wieczorek J (2006)	16773376	172880	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1931	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Crespo A (2006)	17002377	172881	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1932	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Romero I (2007)	17570561	172882	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
3915	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Miller GM (2005)	15764732	174161	175	Amphetamine	beta-Phenylisopropylamine|-methylbenzeneethaneamine|Amphetamin|Amfetaminum|beta-Phenylisopropylamin|alpha-Methylbenzeneethaneamine|1-Phenylpropan-2-amin|1-phenyl-2-aminopropane|-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|Desoxynorephedrine|alpha-Methylphenylethylamine|beta-Aminopropylbenzene|-phenylisopropylamine|rac-amphetamine|Amphetamine|-aminopropylbenzene|Amfetamine	pms-amphetamines xr|act amphet	DRUGBANK	DB00182	C9H13N	small molecule	N06BA01	300-62-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-UHFFFAOYSA-N
3916	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Garcia BG (2005)	15795321	174163	175	Amphetamine	beta-Phenylisopropylamine|-methylbenzeneethaneamine|Amphetamin|Amfetaminum|beta-Phenylisopropylamin|alpha-Methylbenzeneethaneamine|1-Phenylpropan-2-amin|1-phenyl-2-aminopropane|-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|Desoxynorephedrine|alpha-Methylphenylethylamine|beta-Aminopropylbenzene|-phenylisopropylamine|rac-amphetamine|Amphetamine|-aminopropylbenzene|Amfetamine	pms-amphetamines xr|act amphet	DRUGBANK	DB00182	C9H13N	small molecule	N06BA01	300-62-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-UHFFFAOYSA-N
3917	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Lott DC (2005)	15602501	174162	175	Amphetamine	beta-Phenylisopropylamine|-methylbenzeneethaneamine|Amphetamin|Amfetaminum|beta-Phenylisopropylamin|alpha-Methylbenzeneethaneamine|1-Phenylpropan-2-amin|1-phenyl-2-aminopropane|-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|Desoxynorephedrine|alpha-Methylphenylethylamine|beta-Aminopropylbenzene|-phenylisopropylamine|rac-amphetamine|Amphetamine|-aminopropylbenzene|Amfetamine	pms-amphetamines xr|act amphet	DRUGBANK	DB00182	C9H13N	small molecule	N06BA01	300-62-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-UHFFFAOYSA-N
3918	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Kahlig KM (2005)	15728379	174165	175	Amphetamine	beta-Phenylisopropylamine|-methylbenzeneethaneamine|Amphetamin|Amfetaminum|beta-Phenylisopropylamin|alpha-Methylbenzeneethaneamine|1-Phenylpropan-2-amin|1-phenyl-2-aminopropane|-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|Desoxynorephedrine|alpha-Methylphenylethylamine|beta-Aminopropylbenzene|-phenylisopropylamine|rac-amphetamine|Amphetamine|-aminopropylbenzene|Amfetamine	pms-amphetamines xr|act amphet	DRUGBANK	DB00182	C9H13N	small molecule	N06BA01	300-62-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-UHFFFAOYSA-N
3919	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Fone KC (2005)	15661631	174164	175	Amphetamine	beta-Phenylisopropylamine|-methylbenzeneethaneamine|Amphetamin|Amfetaminum|beta-Phenylisopropylamin|alpha-Methylbenzeneethaneamine|1-Phenylpropan-2-amin|1-phenyl-2-aminopropane|-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|Desoxynorephedrine|alpha-Methylphenylethylamine|beta-Aminopropylbenzene|-phenylisopropylamine|rac-amphetamine|Amphetamine|-aminopropylbenzene|Amfetamine	pms-amphetamines xr|act amphet	DRUGBANK	DB00182	C9H13N	small molecule	N06BA01	300-62-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-UHFFFAOYSA-N
3920	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Madras BK (2005)	15950014	174166	175	Amphetamine	beta-Phenylisopropylamine|-methylbenzeneethaneamine|Amphetamin|Amfetaminum|beta-Phenylisopropylamin|alpha-Methylbenzeneethaneamine|1-Phenylpropan-2-amin|1-phenyl-2-aminopropane|-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|Desoxynorephedrine|alpha-Methylphenylethylamine|beta-Aminopropylbenzene|-phenylisopropylamine|rac-amphetamine|Amphetamine|-aminopropylbenzene|Amfetamine	pms-amphetamines xr|act amphet	DRUGBANK	DB00182	C9H13N	small molecule	N06BA01	300-62-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-UHFFFAOYSA-N
4067	108011	1644	-	DDC	AADC	9606	Homo sapiens	inhibitor	target	Kaufmann H (2003)	12885750	174222	183	Carbidopa	L--methyldopahydrazine|(S)-carbidopa|Carbidopum|(S)-()-carbidopa|L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid|(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate|(S)--hydrazino-3,4-dihydroxy--methylbenzenepropanoic acid	sinemet 100/25|sinemet 250/25|	DRUGBANK	DB00190	C10H14N2O4	small molecule	-	28860-95-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZFNLOMSOLWIDK-JTQLQIEISA-N
4068	108011	1644	-	DDC	AADC	9606	Homo sapiens	inhibitor	target	Durso R (2000)	10934669	174219	183	Carbidopa	L--methyldopahydrazine|(S)-carbidopa|Carbidopum|(S)-()-carbidopa|L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid|(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate|(S)--hydrazino-3,4-dihydroxy--methylbenzenepropanoic acid	sinemet 100/25|sinemet 250/25|	DRUGBANK	DB00190	C10H14N2O4	small molecule	-	28860-95-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZFNLOMSOLWIDK-JTQLQIEISA-N
4069	108011	1644	-	DDC	AADC	9606	Homo sapiens	inhibitor	target	Orlefors H (2006)	16184369	174221	183	Carbidopa	L--methyldopahydrazine|(S)-carbidopa|Carbidopum|(S)-()-carbidopa|L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid|(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate|(S)--hydrazino-3,4-dihydroxy--methylbenzenepropanoic acid	sinemet 100/25|sinemet 250/25|	DRUGBANK	DB00190	C10H14N2O4	small molecule	-	28860-95-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZFNLOMSOLWIDK-JTQLQIEISA-N
4070	108011	1644	-	DDC	AADC	9606	Homo sapiens	inhibitor	target	Yee RE (2001)	11709201	172562	183	Carbidopa	L--methyldopahydrazine|(S)-carbidopa|Carbidopum|(S)-()-carbidopa|L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid|(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate|(S)--hydrazino-3,4-dihydroxy--methylbenzenepropanoic acid	sinemet 100/25|sinemet 250/25|	DRUGBANK	DB00190	C10H14N2O4	small molecule	-	28860-95-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZFNLOMSOLWIDK-JTQLQIEISA-N
4071	108011	1644	-	DDC	AADC	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	183	Carbidopa	L--methyldopahydrazine|(S)-carbidopa|Carbidopum|(S)-()-carbidopa|L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid|(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate|(S)--hydrazino-3,4-dihydroxy--methylbenzenepropanoic acid	sinemet 100/25|sinemet 250/25|	DRUGBANK	DB00190	C10H14N2O4	small molecule	-	28860-95-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZFNLOMSOLWIDK-JTQLQIEISA-N
4072	108011	1644	-	DDC	AADC	9606	Homo sapiens	inhibitor	target	Gilbert JA (2000)	11106255	174220	183	Carbidopa	L--methyldopahydrazine|(S)-carbidopa|Carbidopum|(S)-()-carbidopa|L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid|(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate|(S)--hydrazino-3,4-dihydroxy--methylbenzenepropanoic acid	sinemet 100/25|sinemet 250/25|	DRUGBANK	DB00190	C10H14N2O4	small molecule	-	28860-95-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZFNLOMSOLWIDK-JTQLQIEISA-N
4073	108011	1644	-	DDC	AADC	9606	Homo sapiens	inhibitor	target	Calabrese V (2007)	17241115	174218	183	Carbidopa	L--methyldopahydrazine|(S)-carbidopa|Carbidopum|(S)-()-carbidopa|L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid|(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate|(S)--hydrazino-3,4-dihydroxy--methylbenzenepropanoic acid	sinemet 100/25|sinemet 250/25|	DRUGBANK	DB00190	C10H14N2O4	small molecule	-	28860-95-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZFNLOMSOLWIDK-JTQLQIEISA-N
4093	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	John CE (2007)	17459426	174233	184	Phentermine	Phenterminum|Fentermina|alpha,alpha-Dimethylphenethylamine	phentermine resin er|lomaira|f	DRUGBANK	DB00191	C10H15N	small molecule	A08AA01	122-09-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DHHVAGZRUROJKS-UHFFFAOYSA-N
4094	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Gruner JA (2009)	19928382	174236	184	Phentermine	Phenterminum|Fentermina|alpha,alpha-Dimethylphenethylamine	phentermine resin er|lomaira|f	DRUGBANK	DB00191	C10H15N	small molecule	A08AA01	122-09-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DHHVAGZRUROJKS-UHFFFAOYSA-N
4259	111308	5290	-	PIK3CA	CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|p110-alpha	9606	Homo sapiens	unknown	target	Foukas LC (2002)	12145276	174346	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4308	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Boeynaems JM (2005)	15816504	174397	201	Ticlopidine	Ticlopidinum|Ticlopidina	dom-ticlopidine|ticlopidine|my	DRUGBANK	DB00208	C14H14ClNS	small molecule	B01AC05	55142-85-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHWBOXQYWZNQIN-UHFFFAOYSA-N
4309	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Zhan C (2007)	17110146	174400	201	Ticlopidine	Ticlopidinum|Ticlopidina	dom-ticlopidine|ticlopidine|my	DRUGBANK	DB00208	C14H14ClNS	small molecule	B01AC05	55142-85-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHWBOXQYWZNQIN-UHFFFAOYSA-N
4310	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	201	Ticlopidine	Ticlopidinum|Ticlopidina	dom-ticlopidine|ticlopidine|my	DRUGBANK	DB00208	C14H14ClNS	small molecule	B01AC05	55142-85-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHWBOXQYWZNQIN-UHFFFAOYSA-N
4311	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Gachet C (2005)	15955565	174398	201	Ticlopidine	Ticlopidinum|Ticlopidina	dom-ticlopidine|ticlopidine|my	DRUGBANK	DB00208	C14H14ClNS	small molecule	B01AC05	55142-85-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHWBOXQYWZNQIN-UHFFFAOYSA-N
4312	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Storey RF (2001)	11454254	174399	201	Ticlopidine	Ticlopidinum|Ticlopidina	dom-ticlopidine|ticlopidine|my	DRUGBANK	DB00208	C14H14ClNS	small molecule	B01AC05	55142-85-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHWBOXQYWZNQIN-UHFFFAOYSA-N
4716	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Reith ME (2001)	11395483	174615	238	Benzatropine	Benztropine|Tropine Benzohydryl Ether|3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|Benzatropinum|3alpha-(Diphenylmethoxy)tropane|Benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether|3-(diphenylmethoxy)-1H,5H-tropane|3alpha-(Diphenylmethoxy)-1alphah,5alphah-tropane|3endo-benzhydryloxytropane|Benzatropina|3-alpha-(diphenylmethoxy)tropane|3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|3-(diphenylmethoxy)tropane	cogentin inj 1mg/ml|bensylate 	DRUGBANK	DB00245	C21H25NO	small molecule	N04AC01	86-13-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIJXKZJWITVLHI-PMOLBWCYSA-N
4717	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Simoni D (2001)	11277529	174614	238	Benzatropine	Benztropine|Tropine Benzohydryl Ether|3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|Benzatropinum|3alpha-(Diphenylmethoxy)tropane|Benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether|3-(diphenylmethoxy)-1H,5H-tropane|3alpha-(Diphenylmethoxy)-1alphah,5alphah-tropane|3endo-benzhydryloxytropane|Benzatropina|3-alpha-(diphenylmethoxy)tropane|3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|3-(diphenylmethoxy)tropane	cogentin inj 1mg/ml|bensylate 	DRUGBANK	DB00245	C21H25NO	small molecule	N04AC01	86-13-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIJXKZJWITVLHI-PMOLBWCYSA-N
4718	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Zou MF (2001)	11728190	174613	238	Benzatropine	Benztropine|Tropine Benzohydryl Ether|3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|Benzatropinum|3alpha-(Diphenylmethoxy)tropane|Benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether|3-(diphenylmethoxy)-1H,5H-tropane|3alpha-(Diphenylmethoxy)-1alphah,5alphah-tropane|3endo-benzhydryloxytropane|Benzatropina|3-alpha-(diphenylmethoxy)tropane|3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|3-(diphenylmethoxy)tropane	cogentin inj 1mg/ml|bensylate 	DRUGBANK	DB00245	C21H25NO	small molecule	N04AC01	86-13-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIJXKZJWITVLHI-PMOLBWCYSA-N
4719	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Todd CL (1999)	10230713	174612	238	Benzatropine	Benztropine|Tropine Benzohydryl Ether|3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|Benzatropinum|3alpha-(Diphenylmethoxy)tropane|Benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether|3-(diphenylmethoxy)-1H,5H-tropane|3alpha-(Diphenylmethoxy)-1alphah,5alphah-tropane|3endo-benzhydryloxytropane|Benzatropina|3-alpha-(diphenylmethoxy)tropane|3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|3-(diphenylmethoxy)tropane	cogentin inj 1mg/ml|bensylate 	DRUGBANK	DB00245	C21H25NO	small molecule	N04AC01	86-13-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIJXKZJWITVLHI-PMOLBWCYSA-N
4720	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Katz JL (2001)	11349389	174611	238	Benzatropine	Benztropine|Tropine Benzohydryl Ether|3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|Benzatropinum|3alpha-(Diphenylmethoxy)tropane|Benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether|3-(diphenylmethoxy)-1H,5H-tropane|3alpha-(Diphenylmethoxy)-1alphah,5alphah-tropane|3endo-benzhydryloxytropane|Benzatropina|3-alpha-(diphenylmethoxy)tropane|3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|3-(diphenylmethoxy)tropane	cogentin inj 1mg/ml|bensylate 	DRUGBANK	DB00245	C21H25NO	small molecule	N04AC01	86-13-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIJXKZJWITVLHI-PMOLBWCYSA-N
4721	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Kulkarni SS (2006)	16460947	174610	238	Benzatropine	Benztropine|Tropine Benzohydryl Ether|3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|Benzatropinum|3alpha-(Diphenylmethoxy)tropane|Benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether|3-(diphenylmethoxy)-1H,5H-tropane|3alpha-(Diphenylmethoxy)-1alphah,5alphah-tropane|3endo-benzhydryloxytropane|Benzatropina|3-alpha-(diphenylmethoxy)tropane|3alpha-Benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane|3-(diphenylmethoxy)tropane	cogentin inj 1mg/ml|bensylate 	DRUGBANK	DB00245	C21H25NO	small molecule	N04AC01	86-13-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIJXKZJWITVLHI-PMOLBWCYSA-N
5150	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Bourin M (1999)	10434156	174929	278	Venlafaxine	Venlafaxine|Venlafaxinum|Venlafaxina|Elafax	gd-venlafaxine xr|ran-venlafax	DRUGBANK	DB00285	C17H27NO2	small molecule	N06AX16	93413-69-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PNVNVHUZROJLTJ-UHFFFAOYSA-N
5151	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Barkin RL (2000)	11319571	174928	278	Venlafaxine	Venlafaxine|Venlafaxinum|Venlafaxina|Elafax	gd-venlafaxine xr|ran-venlafax	DRUGBANK	DB00285	C17H27NO2	small molecule	N06AX16	93413-69-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PNVNVHUZROJLTJ-UHFFFAOYSA-N
5152	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Dawson LA (1999)	10462128	174930	278	Venlafaxine	Venlafaxine|Venlafaxinum|Venlafaxina|Elafax	gd-venlafaxine xr|ran-venlafax	DRUGBANK	DB00285	C17H27NO2	small molecule	N06AX16	93413-69-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PNVNVHUZROJLTJ-UHFFFAOYSA-N
5153	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Lemke MR (2007)	17187269	174931	278	Venlafaxine	Venlafaxine|Venlafaxinum|Venlafaxina|Elafax	gd-venlafaxine xr|ran-venlafax	DRUGBANK	DB00285	C17H27NO2	small molecule	N06AX16	93413-69-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PNVNVHUZROJLTJ-UHFFFAOYSA-N
5196	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	binder	target	Bymaster FP (2002)	12431845	174994	282	Atomoxetine	Tomoxetine|Tomoxetinum|(-)-Tomoxetine|Tomoxetina	riva-atomoxetine|strattera|pms	DRUGBANK	DB00289	C17H21NO	small molecule	N06BA09	83015-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VHGCDTVCOLNTBX-QGZVFWFLSA-N
6172	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	binder	target	Tatsumi M (1997)	9537821	174430	362	Mirtazapine	Mirtazapinum|Mirtazapin|Mepirzapine|Mirtazapina|1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine|6-Azamianserin|Mirtazapine	dom-mirtazapine|ratio-mirtazap	DRUGBANK	DB00370	C17H19N3	small molecule	N06AX11	85650-52-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RONZAEMNMFQXRA-UHFFFAOYSA-N
6173	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	binder	target	Fernandez J (2005)	15771415	175310	362	Mirtazapine	Mirtazapinum|Mirtazapin|Mepirzapine|Mirtazapina|1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine|6-Azamianserin|Mirtazapine	dom-mirtazapine|ratio-mirtazap	DRUGBANK	DB00370	C17H19N3	small molecule	N06AX11	85650-52-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RONZAEMNMFQXRA-UHFFFAOYSA-N
6214	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	agonist	target	Imming P (2006)	17016423	171742	366	Treprostinil	[[(1R,2R,3aS,9aS)-2-Hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphtalen-5-yl]oxy]acetic acid|Treprostinilo|(1R,2R,3aS,9aS)-[[2,3,3a,4,9,9a-hexahydro-2-hydroxy- 1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl] oxy]acetic acid|Treprostinil|Treprostinilum|Uniprost	remodulin|tyvaso|orenitram	DRUGBANK	DB00374	C23H34O5	small molecule	B01AC21	81846-19-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAJMKGZZBBTTOY-ZFORQUDYSA-N
6215	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	agonist	target	Overington JP (2006)	17139284	171741	366	Treprostinil	[[(1R,2R,3aS,9aS)-2-Hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphtalen-5-yl]oxy]acetic acid|Treprostinilo|(1R,2R,3aS,9aS)-[[2,3,3a,4,9,9a-hexahydro-2-hydroxy- 1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl] oxy]acetic acid|Treprostinil|Treprostinilum|Uniprost	remodulin|tyvaso|orenitram	DRUGBANK	DB00374	C23H34O5	small molecule	B01AC21	81846-19-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAJMKGZZBBTTOY-ZFORQUDYSA-N
6302	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	unknown	target	Kornhuber J (2011)	21909365	175698	373	Amlodipine	3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(O-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate|Amlodipine|Amlodipine free base|3-Ethyl 5-methylester, ()-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate|Amlodipinum|Amlodipino|(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate	amlodipine and benazepril hydr	DRUGBANK	DB00381	C20H25ClN2O5	small molecule	C08CA01|C09BX01|C08GA02|C10BX07|C09XA53|C09BB03|C10BX03|C09BB07|C09XA54|C09DB02|C09DB01|C09DB07|C09DB06|C09DB05|C09DB04|C09DX01|C09BB04|C09DX03|C10BX09|C10BX11	88150-42-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HTIQEAQVCYTUBX-UHFFFAOYSA-N
6806	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6807	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6808	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Volkow ND (1999)	10025684	175966	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6809	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Izenwasser S (1999)	10414438	175967	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6810	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wayment HK (1999)	10037500	175964	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6811	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Dresel SH (1999)	10199939	175965	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6812	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tilley MR (2008)	18698001	175963	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6813	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Viggiano D (2004)	15303308	175968	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
6814	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Volkow ND (1999)	10403500	175969	414	Methylphenidate	alpha-Phenyl-2-piperidineacetic acid methyl ester|Methylphenidatum|Methyl phenidylacetate|Methylphenidate|Metilfenidato|MPH|Methylphenidan|Daytrana|Methyl alpha-phenyl-alpha-2-piperidinylacetate|Methyl alpha-phenyl-alpha-(2-piperidyl)acetate	methylphenidate hydrochloride 	DRUGBANK	DB00422	C14H19NO2	small molecule	N06BA04	113-45-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-UHFFFAOYSA-N
7048	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	unknown	target	Lomenzo SA (1999)	10612583	176165	446	Pethidine	Meperidine|Petidina|Pethidinum|Sauteralgyl|Spasmodolin|Petydyna|Spasmedal|Pthidine|Isonipecane|Pethidin|Pethidine dbl	demerol 50 mg/ml   (multiple d	DRUGBANK	DB00454	C15H21NO2	small molecule	N02AB02|N02AB52|N02AG03|N02AB72	57-42-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XADCESSVHJOZHK-UHFFFAOYSA-N
7049	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	unknown	target	Gu X (2010)	20980153	176161	446	Pethidine	Meperidine|Petidina|Pethidinum|Sauteralgyl|Spasmodolin|Petydyna|Spasmedal|Pthidine|Isonipecane|Pethidin|Pethidine dbl	demerol 50 mg/ml   (multiple d	DRUGBANK	DB00454	C15H21NO2	small molecule	N02AB02|N02AB52|N02AG03|N02AB72	57-42-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XADCESSVHJOZHK-UHFFFAOYSA-N
7050	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	unknown	target	Lomenzo SA (2005)	15743177	176160	446	Pethidine	Meperidine|Petidina|Pethidinum|Sauteralgyl|Spasmodolin|Petydyna|Spasmedal|Pthidine|Isonipecane|Pethidin|Pethidine dbl	demerol 50 mg/ml   (multiple d	DRUGBANK	DB00454	C15H21NO2	small molecule	N02AB02|N02AB52|N02AG03|N02AB72	57-42-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XADCESSVHJOZHK-UHFFFAOYSA-N
7111	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	unknown	target	Melikian HE (1999)	10479674	176217	450	Imipramine	N-(-dimethylaminopropyl)iminodibenzyl|Imipraminum|Antideprin|3-(5H-DIBENZO[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine|10,11-dihydro-N,N-Dimethyl-5H-dibenz[b,F]azepine-5-propanamine|Irmin|Imipramine|Imizine|5-[3-(dimethylamino)Propyl]-10,11-dihydro-5H-dibenz[b,F]azepine|Melipramine|N-(gamma-Dimethylaminopropyl)iminodibenzyl|Imipramin	tofranil|imipramine tab 25mg|i	DRUGBANK	DB00458	C19H24N2	small molecule	N06AA02	50-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCGWQEUPMDMJNV-UHFFFAOYSA-N
7313	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	468	Duloxetine	(S)-duloxetine|(3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine	ipg-duloxetine|cymbalta|mylan-	DRUGBANK	DB00476	C18H19NOS	small molecule	N06AX21	116539-59-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZEUITGRIYCTCEM-KRWDZBQOSA-N
7314	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Hunziker ME (2005)	16199241	176320	468	Duloxetine	(S)-duloxetine|(3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine	ipg-duloxetine|cymbalta|mylan-	DRUGBANK	DB00476	C18H19NOS	small molecule	N06AX21	116539-59-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZEUITGRIYCTCEM-KRWDZBQOSA-N
7315	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	468	Duloxetine	(S)-duloxetine|(3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine	ipg-duloxetine|cymbalta|mylan-	DRUGBANK	DB00476	C18H19NOS	small molecule	N06AX21	116539-59-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZEUITGRIYCTCEM-KRWDZBQOSA-N
7316	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Pereira P (2009)	18973814	176325	468	Duloxetine	(S)-duloxetine|(3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine	ipg-duloxetine|cymbalta|mylan-	DRUGBANK	DB00476	C18H19NOS	small molecule	N06AX21	116539-59-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZEUITGRIYCTCEM-KRWDZBQOSA-N
7317	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Carter NJ (2009)	19480470	176315	468	Duloxetine	(S)-duloxetine|(3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine	ipg-duloxetine|cymbalta|mylan-	DRUGBANK	DB00476	C18H19NOS	small molecule	N06AX21	116539-59-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZEUITGRIYCTCEM-KRWDZBQOSA-N
7328	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	unknown	target	Yoshida Y (1985)	2419314	176337	469	Chlorpromazine	Chlorpromazine|Chloropromazine|Largactil|CPZ|N-(3-Dimethylaminopropyl)-3-chlorophenothiazine|Aminazine|Chlorpromados|Chlorpromazinum|Clorpromazina|Chlorderazin|3-(2-chloro-10H-Phenothiazin-10-yl)-N,N-dimethyl-1-propanamine|Contomin|3-(2-Chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine|Thorazine	chlorpromanyl 20 syr|chlorprom	DRUGBANK	DB00477	C17H19ClN2S	small molecule	N05AA01	50-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPEIMTDSQAKGNT-UHFFFAOYSA-N
8210	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Goettl VM (2000)	10980236	177025	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
8211	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Purkerson-Parker S (2001)	11719704	177024	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
8212	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
8213	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Saunders C (2000)	10823899	177021	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
8214	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tidjane Corera A (2001)	11248372	177020	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
8215	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Kulkarni SS (2002)	12213055	177023	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
8216	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Houlihan WJ (2002)	12213053	177022	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
8217	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Itzhak Y (1999)	10082805	177019	569	Mazindol	Sanorex|Mazindolum|Mazindolo|Mazindol	sanorex	DRUGBANK	DB00579	C16H13ClN2O	small molecule	A08AA05	22232-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPXSCAKFGYXMGA-UHFFFAOYSA-N
9319	107562	1140	-	CHRNB1	ACHRB|CHRNB|CMS1D|CMS2A|SCCMS	9606	Homo sapiens	allosteric modulator	target	Guillou C (2000)	20480924	177724	664	Galantamine	Galanthamine|(-)-Galanthamine	reminyl   -(12mg)|pms-galantam	DRUGBANK	DB00674	C17H21NO3	small molecule	N06DA04	357-70-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASUTZQLVASHGKV-JDFRZJQESA-N
9320	107562	1140	-	CHRNB1	ACHRB|CHRNB|CMS1D|CMS2A|SCCMS	9606	Homo sapiens	allosteric modulator	target	Scott LJ (2000)	11129124	177725	664	Galantamine	Galanthamine|(-)-Galanthamine	reminyl   -(12mg)|pms-galantam	DRUGBANK	DB00674	C17H21NO3	small molecule	N06DA04	357-70-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASUTZQLVASHGKV-JDFRZJQESA-N
9321	107562	1140	-	CHRNB1	ACHRB|CHRNB|CMS1D|CMS2A|SCCMS	9606	Homo sapiens	allosteric modulator	target	Lilienfeld S (2000)	10971048	177719	664	Galantamine	Galanthamine|(-)-Galanthamine	reminyl   -(12mg)|pms-galantam	DRUGBANK	DB00674	C17H21NO3	small molecule	N06DA04	357-70-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASUTZQLVASHGKV-JDFRZJQESA-N
9322	107562	1140	-	CHRNB1	ACHRB|CHRNB|CMS1D|CMS2A|SCCMS	9606	Homo sapiens	allosteric modulator	target	Woodruff-Pak DS (2002)	12481195	177718	664	Galantamine	Galanthamine|(-)-Galanthamine	reminyl   -(12mg)|pms-galantam	DRUGBANK	DB00674	C17H21NO3	small molecule	N06DA04	357-70-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASUTZQLVASHGKV-JDFRZJQESA-N
9323	107562	1140	-	CHRNB1	ACHRB|CHRNB|CMS1D|CMS2A|SCCMS	9606	Homo sapiens	allosteric modulator	target	Lilienfeld S (2002)	12177686	177716	664	Galantamine	Galanthamine|(-)-Galanthamine	reminyl   -(12mg)|pms-galantam	DRUGBANK	DB00674	C17H21NO3	small molecule	N06DA04	357-70-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASUTZQLVASHGKV-JDFRZJQESA-N
9324	107562	1140	-	CHRNB1	ACHRB|CHRNB|CMS1D|CMS2A|SCCMS	9606	Homo sapiens	allosteric modulator	target	Olin J (2002)	12137632	177715	664	Galantamine	Galanthamine|(-)-Galanthamine	reminyl   -(12mg)|pms-galantam	DRUGBANK	DB00674	C17H21NO3	small molecule	N06DA04	357-70-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASUTZQLVASHGKV-JDFRZJQESA-N
9829	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Sato T (2000)	10685879	178036	711	Procaine	Procaina|4-aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl 4-aminobenzoate|2-Diethylaminoethyl p-aminobenzoate|Vitamin H3|Procainum|Novocaine|p-Aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl p-aminobenzoate	novocain 20 mg/ml|novocain liq	DRUGBANK	DB00721	C13H20N2O2	small molecule	S01HA05|C05AD05|N01BA52|N01BA02	59-46-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MFDFERRIHVXMIY-UHFFFAOYSA-N
9830	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wilcox KM (2005)	16206183	178035	711	Procaine	Procaina|4-aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl 4-aminobenzoate|2-Diethylaminoethyl p-aminobenzoate|Vitamin H3|Procainum|Novocaine|p-Aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl p-aminobenzoate	novocain 20 mg/ml|novocain liq	DRUGBANK	DB00721	C13H20N2O2	small molecule	S01HA05|C05AD05|N01BA52|N01BA02	59-46-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MFDFERRIHVXMIY-UHFFFAOYSA-N
9831	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Kiyatkin EA (2006)	16956595	178034	711	Procaine	Procaina|4-aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl 4-aminobenzoate|2-Diethylaminoethyl p-aminobenzoate|Vitamin H3|Procainum|Novocaine|p-Aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl p-aminobenzoate	novocain 20 mg/ml|novocain liq	DRUGBANK	DB00721	C13H20N2O2	small molecule	S01HA05|C05AD05|N01BA52|N01BA02	59-46-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MFDFERRIHVXMIY-UHFFFAOYSA-N
9903	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	716	Trimipramine	Trimipramine|Trimeproprimine|RP-7162|Trimipramina|10,11-dihydro-N,N,beta-Trimethyl-5H-dibenz[b,F]azepine-5-propanamine|5-(gamma-dimethylamino-beta-Methylpropyl)-10,11-dihydro-5H-dibenzo[b,F]azepine|Trimeprimina|Trimeprimine|Trimipraminum|beta-Methylimipramine|5-[3-(dimethylamino)-2-Methylpropyl]-10,11-dihydro-5H-dibenz[b,F]azepine|Sapilent	nu-trimipramine tab 100mg|trim	DRUGBANK	DB00726	C20H26N2	small molecule	N06AA06	739-71-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSCDBOWYZJWBIY-UHFFFAOYSA-N
10034	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Swanson JM (2003)	14658934	178147	735	Modafinil	Modafinilo|Provigil|Moderateafinil|Modafinilum|Modafinil	auro-modafinil|ipg-modafinil|p	DRUGBANK	DB00745	C15H15NO2S	small molecule	N06BA07	68693-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFGHCGITMMYXAQ-UHFFFAOYSA-N
10035	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Madras BK (2006)	16885432	178150	735	Modafinil	Modafinilo|Provigil|Moderateafinil|Modafinilum|Modafinil	auro-modafinil|ipg-modafinil|p	DRUGBANK	DB00745	C15H15NO2S	small molecule	N06BA07	68693-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFGHCGITMMYXAQ-UHFFFAOYSA-N
10036	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Dopheide MM (2007)	17477916	178151	735	Modafinil	Modafinilo|Provigil|Moderateafinil|Modafinilum|Modafinil	auro-modafinil|ipg-modafinil|p	DRUGBANK	DB00745	C15H15NO2S	small molecule	N06BA07	68693-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFGHCGITMMYXAQ-UHFFFAOYSA-N
10037	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wisor JP (2001)	11222668	178149	735	Modafinil	Modafinilo|Provigil|Moderateafinil|Modafinilum|Modafinil	auro-modafinil|ipg-modafinil|p	DRUGBANK	DB00745	C15H15NO2S	small molecule	N06BA07	68693-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFGHCGITMMYXAQ-UHFFFAOYSA-N
10038	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Zhou J (2004)	15537337	178148	735	Modafinil	Modafinilo|Provigil|Moderateafinil|Modafinilum|Modafinil	auro-modafinil|ipg-modafinil|p	DRUGBANK	DB00745	C15H15NO2S	small molecule	N06BA07	68693-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFGHCGITMMYXAQ-UHFFFAOYSA-N
10178	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Wihlborg AK (2004)	15308557	178244	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10179	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Dorsam RT (2003)	14668029	178245	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10180	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10181	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Savi P (2006)	16835302	178240	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10182	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	van Gestel MA (2003)	12615691	178241	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10183	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Herbert JM (2003)	15199474	178242	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10184	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Gladding P (2008)	19463375	178243	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10185	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Wang L (2004)	15291969	178239	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10186	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Taubert D (2004)	15269827	178238	748	Clopidogrel	(+)-Clopidogrel|Clopidogrelum	ipg-clopidogrel|mar-clopidogre	DRUGBANK	DB00758	C16H16ClNO2S	small molecule	B01AC04	113665-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKTWGGQPFAXNFI-HNNXBMFYSA-N
10920	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	820	Phenmetrazine	Fenmetrazina|Phenmetrazinum|2-Phenyl-3-methylmorpholine|Fenmetrazin|Phenmetrazin	-	DRUGBANK	DB00830	C11H15NO	small molecule	-	134-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OOBHFESNSZDWIU-UHFFFAOYSA-N
10921	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Rothman RB (2002)	12106802	178586	820	Phenmetrazine	Fenmetrazina|Phenmetrazinum|2-Phenyl-3-methylmorpholine|Fenmetrazin|Phenmetrazin	-	DRUGBANK	DB00830	C11H15NO	small molecule	-	134-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OOBHFESNSZDWIU-UHFFFAOYSA-N
10922	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Rothman RB (2006)	17017961	178585	820	Phenmetrazine	Fenmetrazina|Phenmetrazinum|2-Phenyl-3-methylmorpholine|Fenmetrazin|Phenmetrazin	-	DRUGBANK	DB00830	C11H15NO	small molecule	-	134-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OOBHFESNSZDWIU-UHFFFAOYSA-N
10923	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	820	Phenmetrazine	Fenmetrazina|Phenmetrazinum|2-Phenyl-3-methylmorpholine|Fenmetrazin|Phenmetrazin	-	DRUGBANK	DB00830	C11H15NO	small molecule	-	134-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OOBHFESNSZDWIU-UHFFFAOYSA-N
11183	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Foley KF (2002)	12373557	178698	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11184	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wee S (2004)	15189772	178697	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11242	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Kahlig KM (2005)	15728379	174165	855	Benzphetamine	Benzfetamina|(+)-benzphetamine|Benzfetamine|(S)-(+)-benzphetamine|N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine|Benzfetaminum|(S)-(+)-N-benzyl-N,-dimethylphenethylamine|(S)-benzphetamine|(+)-N-Benzyl-N,alpha-dimethylphenethylamine|D-N-Methyl-N-benzyl-beta-phenylisopropylamine|(AlphaS)-N,alpha-dimethylphenethylamine|Benzphetamine|Benzaphetamine|(+)-N,-dimethyl-N-(phenylmethyl)-benzeneethanamine|Benzylamphetamine|(+)-N,alpha-Dimethyl-N-(phenylmethyl)-benzeneethanamine|d-N-methyl-N-benzyl--phenylisopropylamine|(S)-(+)-N-Benzyl-N,alpha-dimethylphenethylamine|(+)-N-benzyl-N,-dimethylphenethylamine	benzphetamine|didrex|regimex|b	DRUGBANK	DB00865	C17H21N	small molecule	-	156-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YXKTVDFXDRQTKV-HNNXBMFYSA-N
11243	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Sulzer D (2005)	15955613	174152	855	Benzphetamine	Benzfetamina|(+)-benzphetamine|Benzfetamine|(S)-(+)-benzphetamine|N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine|Benzfetaminum|(S)-(+)-N-benzyl-N,-dimethylphenethylamine|(S)-benzphetamine|(+)-N-Benzyl-N,alpha-dimethylphenethylamine|D-N-Methyl-N-benzyl-beta-phenylisopropylamine|(AlphaS)-N,alpha-dimethylphenethylamine|Benzphetamine|Benzaphetamine|(+)-N,-dimethyl-N-(phenylmethyl)-benzeneethanamine|Benzylamphetamine|(+)-N,alpha-Dimethyl-N-(phenylmethyl)-benzeneethanamine|d-N-methyl-N-benzyl--phenylisopropylamine|(S)-(+)-N-Benzyl-N,alpha-dimethylphenethylamine|(+)-N-benzyl-N,-dimethylphenethylamine	benzphetamine|didrex|regimex|b	DRUGBANK	DB00865	C17H21N	small molecule	-	156-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YXKTVDFXDRQTKV-HNNXBMFYSA-N
11619	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Carrera MR (2004)	15351386	178995	897	Cocaine	Methyl benzoylecgonine|Cocainum|Cocaine|Kokain|L-Cocain|2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)|Benzoylmethylecgonine|Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate|Cocain|beta-Cocain|L-Cocaine|(-)-Cocaine|()-cocaine|Neurocaine|[1R-(Exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester|Cocaina	cocaine hydrochloride top sol 	DRUGBANK	DB00907	C17H21NO4	small molecule	N01BC01|S02DA02|R02AD03|S01HA01	50-36-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPUCINDJVBIVPJ-LJISPDSOSA-N
11620	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Rothman RB (1999)	10420171	179003	897	Cocaine	Methyl benzoylecgonine|Cocainum|Cocaine|Kokain|L-Cocain|2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)|Benzoylmethylecgonine|Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate|Cocain|beta-Cocain|L-Cocaine|(-)-Cocaine|()-cocaine|Neurocaine|[1R-(Exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester|Cocaina	cocaine hydrochloride top sol 	DRUGBANK	DB00907	C17H21NO4	small molecule	N01BC01|S02DA02|R02AD03|S01HA01	50-36-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPUCINDJVBIVPJ-LJISPDSOSA-N
11621	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wilson JM (1996)	8797532	179002	897	Cocaine	Methyl benzoylecgonine|Cocainum|Cocaine|Kokain|L-Cocain|2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)|Benzoylmethylecgonine|Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate|Cocain|beta-Cocain|L-Cocaine|(-)-Cocaine|()-cocaine|Neurocaine|[1R-(Exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester|Cocaina	cocaine hydrochloride top sol 	DRUGBANK	DB00907	C17H21NO4	small molecule	N01BC01|S02DA02|R02AD03|S01HA01	50-36-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPUCINDJVBIVPJ-LJISPDSOSA-N
11622	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	897	Cocaine	Methyl benzoylecgonine|Cocainum|Cocaine|Kokain|L-Cocain|2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)|Benzoylmethylecgonine|Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate|Cocain|beta-Cocain|L-Cocaine|(-)-Cocaine|()-cocaine|Neurocaine|[1R-(Exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester|Cocaina	cocaine hydrochloride top sol 	DRUGBANK	DB00907	C17H21NO4	small molecule	N01BC01|S02DA02|R02AD03|S01HA01	50-36-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPUCINDJVBIVPJ-LJISPDSOSA-N
11623	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Kim DI (2003)	12672245	179004	897	Cocaine	Methyl benzoylecgonine|Cocainum|Cocaine|Kokain|L-Cocain|2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)|Benzoylmethylecgonine|Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate|Cocain|beta-Cocain|L-Cocaine|(-)-Cocaine|()-cocaine|Neurocaine|[1R-(Exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester|Cocaina	cocaine hydrochloride top sol 	DRUGBANK	DB00907	C17H21NO4	small molecule	N01BC01|S02DA02|R02AD03|S01HA01	50-36-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZPUCINDJVBIVPJ-LJISPDSOSA-N
12114	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Yu H (2000)	11131159	179214	927	Diethylpropion	Diethylpropion|2-(Diethylamino)propiophenone|2-(Diethylamino)-1-phenyl-1-propanone|Diethylcathinone|Amfepramone|alpha-Benzoyltriethylamine|(+-)-Diethylpropion|()-diethylpropion|alpha-Diethylaminopropiophenone|Anfepramona|Amfepramonum|1-phenyl-2-diethylamino-1-propanone	tenuate dospan|diethylpropion 	DRUGBANK	DB00937	C13H19NO	small molecule	A08AA03	90-84-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXEPPPIWZFICOJ-UHFFFAOYSA-N
12115	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Arias HR (2009)	19897080	179213	927	Diethylpropion	Diethylpropion|2-(Diethylamino)propiophenone|2-(Diethylamino)-1-phenyl-1-propanone|Diethylcathinone|Amfepramone|alpha-Benzoyltriethylamine|(+-)-Diethylpropion|()-diethylpropion|alpha-Diethylaminopropiophenone|Anfepramona|Amfepramonum|1-phenyl-2-diethylamino-1-propanone	tenuate dospan|diethylpropion 	DRUGBANK	DB00937	C13H19NO	small molecule	A08AA03	90-84-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXEPPPIWZFICOJ-UHFFFAOYSA-N
12380	108011	1644	-	DDC	AADC	9606	Homo sapiens	unknown	target	SOURKES TL (1954)	13189588	179398	958	Methyldopa	-methyl-L-dopa|alpha-methyl-L-dopa|Methyldopa anhydrous|AMD|Methyl dopa|L-alpha-Methyldopa|(S)-(-)-alpha-Methyldopa|Anhydrous methyldopa|Alphamethyldopa|-Methyl dopa|alpha-Methyl dopa|Alpha medopa|L-Methyl Dopa|3-Hydroxy-alpha-methyl-L-tyrosine	methyldopa 125 tab 125mg|novo-	DRUGBANK	DB00968	C10H13NO4	small molecule	-	555-30-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJCSPKMFHVPWAR-UEQNJFAPNA-N
12525	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inducer	target	Ostadali MR (2004)	17301410	179521	978	Dopamine	4-(2-Aminoethyl)benzene-1,2-diol|Deoxyepinephrine|4-(2-Aminoethyl)pyrocatechol|Dopaminum|4-(2-Aminoethyl)-1,2-benzenediol|2-(3,4-Dihydroxyphenyl)ethylamine|Dopamina|Dophamine|Dopamine|3,4-Dihydroxyphenethylamine|Dopamin|Oxytyramine|Hydroxytyramine|4-(2-Aminoethyl)catechol|3-Hydroxytyramine|Hydroxytyramin	dopamine hydrochloride and dex	DRUGBANK	DB00988	C8H11NO2	small molecule	C01CA04	51-61-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VYFYYTLLBUKUHU-UHFFFAOYSA-N
12573	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	inhibitor	target	Anstey A (1998)	18020555	179566	983	Azathioprine	Imuran (tn)|6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine|6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine	azathioprine sodium for inject	DRUGBANK	DB00993	C9H7N7O2S	small molecule	L04AX01	446-86-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LMEKQMALGUDUQG-UHFFFAOYSA-N
12574	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	inhibitor	target	Dubinsky MC (2004)	15354273	179565	983	Azathioprine	Imuran (tn)|6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine|6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine	azathioprine sodium for inject	DRUGBANK	DB00993	C9H7N7O2S	small molecule	L04AX01	446-86-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LMEKQMALGUDUQG-UHFFFAOYSA-N
12805	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Baptiste DC (2004)	15304547	179708	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12806	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Lee SM (2003)	14588118	179706	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12807	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Arvin KL (2002)	12112047	179707	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12808	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Dommergues MA (2003)	14568022	179705	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12809	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Chen M (2000)	10888929	179696	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12810	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Kim HS (2009)	18977395	179697	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12997	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	inhibitor	target	Dubinsky MC (2004)	15354273	179565	1022	Mercaptopurine	Mercapurin|Mercaptopurina|6-Thiohypoxanthine|6-Thioxopurine|6-MP|6 MP|mercaptopurinum|6-Mercaptopurine	mercaptopurine|purixan|purinet	DRUGBANK	DB01033	C5H4N4S	small molecule	L01BB02	50-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GLVAUDGFNGKCSF-UHFFFAOYSA-N
13749	113986	8398	CTA-228A9.2	PLA2G6	CaI-PLA2|GVI|INAD1|IPLA2-VIA|NBIA2|NBIA2A|NBIA2B|PARK14|PLA2|PNPLA9|iPLA2|iPLA2beta	9606	Homo sapiens	inhibitor	target	Sastry BV (1999)	10229494	180139	1091	Quinacrine	Mepacrine|6-chloro-9-((4-(Diethylamino)-1-methylbutyl)amino)-2-methoxyacridine|2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine|3-chloro-7-Methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine|Quinacrine|N(4)-(6-chloro-2-Methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine	-	DRUGBANK	DB01103	C23H30ClN3O	small molecule	P01AX05	83-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GPKJTRJOBQGKQK-UHFFFAOYSA-N
13750	113986	8398	CTA-228A9.2	PLA2G6	CaI-PLA2|GVI|INAD1|IPLA2-VIA|NBIA2|NBIA2A|NBIA2B|PARK14|PLA2|PNPLA9|iPLA2|iPLA2beta	9606	Homo sapiens	inhibitor	target	Nuttle LC (1999)	10199854	180138	1091	Quinacrine	Mepacrine|6-chloro-9-((4-(Diethylamino)-1-methylbutyl)amino)-2-methoxyacridine|2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine|3-chloro-7-Methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine|Quinacrine|N(4)-(6-chloro-2-Methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine	-	DRUGBANK	DB01103	C23H30ClN3O	small molecule	P01AX05	83-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GPKJTRJOBQGKQK-UHFFFAOYSA-N
13751	113986	8398	CTA-228A9.2	PLA2G6	CaI-PLA2|GVI|INAD1|IPLA2-VIA|NBIA2|NBIA2A|NBIA2B|PARK14|PLA2|PNPLA9|iPLA2|iPLA2beta	9606	Homo sapiens	inhibitor	target	Lohmann CH (1999)	10449625	180140	1091	Quinacrine	Mepacrine|6-chloro-9-((4-(Diethylamino)-1-methylbutyl)amino)-2-methoxyacridine|2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine|3-chloro-7-Methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine|Quinacrine|N(4)-(6-chloro-2-Methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine	-	DRUGBANK	DB01103	C23H30ClN3O	small molecule	P01AX05	83-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GPKJTRJOBQGKQK-UHFFFAOYSA-N
13752	113986	8398	CTA-228A9.2	PLA2G6	CaI-PLA2|GVI|INAD1|IPLA2-VIA|NBIA2|NBIA2A|NBIA2B|PARK14|PLA2|PNPLA9|iPLA2|iPLA2beta	9606	Homo sapiens	inhibitor	target	Schwartz Z (2000)	10653606	180142	1091	Quinacrine	Mepacrine|6-chloro-9-((4-(Diethylamino)-1-methylbutyl)amino)-2-methoxyacridine|2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine|3-chloro-7-Methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine|Quinacrine|N(4)-(6-chloro-2-Methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine	-	DRUGBANK	DB01103	C23H30ClN3O	small molecule	P01AX05	83-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GPKJTRJOBQGKQK-UHFFFAOYSA-N
13753	113986	8398	CTA-228A9.2	PLA2G6	CaI-PLA2|GVI|INAD1|IPLA2-VIA|NBIA2|NBIA2A|NBIA2B|PARK14|PLA2|PNPLA9|iPLA2|iPLA2beta	9606	Homo sapiens	inhibitor	target	Sylvia VL (2001)	11455568	180141	1091	Quinacrine	Mepacrine|6-chloro-9-((4-(Diethylamino)-1-methylbutyl)amino)-2-methoxyacridine|2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine|3-chloro-7-Methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine|Quinacrine|N(4)-(6-chloro-2-Methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine	-	DRUGBANK	DB01103	C23H30ClN3O	small molecule	P01AX05	83-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GPKJTRJOBQGKQK-UHFFFAOYSA-N
13772	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Lemke MR (2007)	17187269	174931	1092	Sertraline	cis-(+)-Sertraline|Sertraline|(+)-Sertraline|Sertralina|(1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine|(1S,4S)-Sertraline|CP 51974|Sertralinum	ipg-sertraline|sertraline|nu-s	DRUGBANK	DB01104	C17H17Cl2N	small molecule	N06AB06	79617-96-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VGKDLMBJGBXTGI-SJCJKPOMSA-N
13773	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	1092	Sertraline	cis-(+)-Sertraline|Sertraline|(+)-Sertraline|Sertralina|(1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine|(1S,4S)-Sertraline|CP 51974|Sertralinum	ipg-sertraline|sertraline|nu-s	DRUGBANK	DB01104	C17H17Cl2N	small molecule	N06AB06	79617-96-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VGKDLMBJGBXTGI-SJCJKPOMSA-N
13774	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Nemeroff CB (2004)	15181382	180162	1092	Sertraline	cis-(+)-Sertraline|Sertraline|(+)-Sertraline|Sertralina|(1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine|(1S,4S)-Sertraline|CP 51974|Sertralinum	ipg-sertraline|sertraline|nu-s	DRUGBANK	DB01104	C17H17Cl2N	small molecule	N06AB06	79617-96-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VGKDLMBJGBXTGI-SJCJKPOMSA-N
13775	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Goodnick PJ (1998)	9808077	180160	1092	Sertraline	cis-(+)-Sertraline|Sertraline|(+)-Sertraline|Sertralina|(1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine|(1S,4S)-Sertraline|CP 51974|Sertralinum	ipg-sertraline|sertraline|nu-s	DRUGBANK	DB01104	C17H17Cl2N	small molecule	N06AB06	79617-96-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VGKDLMBJGBXTGI-SJCJKPOMSA-N
13776	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Ghanizadeh A (2008)	18664165	180161	1092	Sertraline	cis-(+)-Sertraline|Sertraline|(+)-Sertraline|Sertralina|(1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine|(1S,4S)-Sertraline|CP 51974|Sertralinum	ipg-sertraline|sertraline|nu-s	DRUGBANK	DB01104	C17H17Cl2N	small molecule	N06AB06	79617-96-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VGKDLMBJGBXTGI-SJCJKPOMSA-N
13799	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Balcioglu A (2000)	10974319	180174	1093	Sibutramine	Sibutraminum|Butramin|Sibutramina	apo-sibutramine|meridia	DRUGBANK	DB01105	C17H26ClN	small molecule	A08AA10	106650-56-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UNAANXDKBXWMLN-UHFFFAOYSA-N
13800	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Berke EM (2000)	10929704	180171	1093	Sibutramine	Sibutraminum|Butramin|Sibutramina	apo-sibutramine|meridia	DRUGBANK	DB01105	C17H26ClN	small molecule	A08AA10	106650-56-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UNAANXDKBXWMLN-UHFFFAOYSA-N
13801	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tziomalos K (2009)	19475780	180170	1093	Sibutramine	Sibutraminum|Butramin|Sibutramina	apo-sibutramine|meridia	DRUGBANK	DB01105	C17H26ClN	small molecule	A08AA10	106650-56-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UNAANXDKBXWMLN-UHFFFAOYSA-N
13802	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Nakagawa T (2001)	15111248	180173	1093	Sibutramine	Sibutraminum|Butramin|Sibutramina	apo-sibutramine|meridia	DRUGBANK	DB01105	C17H26ClN	small molecule	A08AA10	106650-56-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UNAANXDKBXWMLN-UHFFFAOYSA-N
13803	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Gomis Barbara R (2004)	15382615	180049	1093	Sibutramine	Sibutraminum|Butramin|Sibutramina	apo-sibutramine|meridia	DRUGBANK	DB01105	C17H26ClN	small molecule	A08AA10	106650-56-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UNAANXDKBXWMLN-UHFFFAOYSA-N
13804	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Krahn LE (2001)	11152984	180169	1093	Sibutramine	Sibutraminum|Butramin|Sibutramina	apo-sibutramine|meridia	DRUGBANK	DB01105	C17H26ClN	small molecule	A08AA10	106650-56-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UNAANXDKBXWMLN-UHFFFAOYSA-N
13906	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	1102	Chlorphenamine	Chlorophenylpyridamine|Chlorphenaminum|-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine|3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine|1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine|Chlorpheniramine polistirex|Chlorpheniraminum|-(4-chlorophenyl)--(2-pyridyl)propyldimethylamine|Clorfeniramina|Chlorpheniramine|Clorfenamina|2-[p-chloro--[2-(dimethylamino)ethyl]benzyl]pyridine|1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane|Chlorphenamin	allergy mutli-symptom|children	DRUGBANK	DB01114	C16H19ClN2	small molecule	R06AB54|R06AB04	132-22-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SOYKEARSMXGVTM-UHFFFAOYSA-N
14181	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Lapa GB (2005)	15627433	180352	1134	Diphenylpyraline	1-Methyl-4-hydroxypiperidine benzhydryl ether|4-(Benzhydryloxy)-N-methylpiperidine|Difenilpiralina|Diphenylpyralamine|Diphenylpyralinum|1-Methyl-4-piperidyl benzhydryl ether|4-(Benzhydryloxy)-1-methylpiperidine	biohisdine dm decongestant|ora	DRUGBANK	DB01146	C19H23NO	small molecule	R06AA57|R06AA07	147-20-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWQUZNMMYNAXSL-UHFFFAOYSA-N
14219	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	1137	Nefazodone	Nefazodonum|Nefazodona|1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one|Nefazodone	serzone-5ht2|nefazodone hydroc	DRUGBANK	DB01149	C25H32ClN5O2	small molecule	N06AX06	83366-66-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VRBKIVRKKCLPHA-UHFFFAOYSA-N
14266	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	inhibitor	target	Zeidan YH (2006)	16803890	180388	1139	Desipramine	N-(3-methylaminopropyl)iminobibenzyl|5-(-methylaminopropyl)iminodibenzyl|5-(gamma-Methylaminopropyl)iminodibenzyl|DMI|Dmthylimipramine|Desipramine|Norimipramine|3-(10,11-DIHYDRO-5H-dibenzo[b,F]azepin-5-yl)-N-methylpropan-1-amine|Desipramina|Monodemethylimipramine|Desipraminum|Desmethylimipramine|Desipramin	pms-desipramine - tab 100mg|de	DRUGBANK	DB01151	C18H22N2	small molecule	N06AA01	50-47-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYAFALTSJYZDH-UHFFFAOYSA-N
14267	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	inhibitor	target	Hurwitz R (1994)	7945993	180386	1139	Desipramine	N-(3-methylaminopropyl)iminobibenzyl|5-(-methylaminopropyl)iminodibenzyl|5-(gamma-Methylaminopropyl)iminodibenzyl|DMI|Dmthylimipramine|Desipramine|Norimipramine|3-(10,11-DIHYDRO-5H-dibenzo[b,F]azepin-5-yl)-N-methylpropan-1-amine|Desipramina|Monodemethylimipramine|Desipraminum|Desmethylimipramine|Desipramin	pms-desipramine - tab 100mg|de	DRUGBANK	DB01151	C18H22N2	small molecule	N06AA01	50-47-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYAFALTSJYZDH-UHFFFAOYSA-N
14268	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	inhibitor	target	Kornhuber J (2010)	20502000	180387	1139	Desipramine	N-(3-methylaminopropyl)iminobibenzyl|5-(-methylaminopropyl)iminodibenzyl|5-(gamma-Methylaminopropyl)iminodibenzyl|DMI|Dmthylimipramine|Desipramine|Norimipramine|3-(10,11-DIHYDRO-5H-dibenzo[b,F]azepin-5-yl)-N-methylpropan-1-amine|Desipramina|Monodemethylimipramine|Desipraminum|Desmethylimipramine|Desipramin	pms-desipramine - tab 100mg|de	DRUGBANK	DB01151	C18H22N2	small molecule	N06AA01	50-47-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYAFALTSJYZDH-UHFFFAOYSA-N
14269	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	inhibitor	target	Koelzer M (2004)	14960314	180384	1139	Desipramine	N-(3-methylaminopropyl)iminobibenzyl|5-(-methylaminopropyl)iminodibenzyl|5-(gamma-Methylaminopropyl)iminodibenzyl|DMI|Dmthylimipramine|Desipramine|Norimipramine|3-(10,11-DIHYDRO-5H-dibenzo[b,F]azepin-5-yl)-N-methylpropan-1-amine|Desipramina|Monodemethylimipramine|Desipraminum|Desmethylimipramine|Desipramin	pms-desipramine - tab 100mg|de	DRUGBANK	DB01151	C18H22N2	small molecule	N06AA01	50-47-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYAFALTSJYZDH-UHFFFAOYSA-N
14270	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	inhibitor	target	Testai FD (2004)	14689449	180385	1139	Desipramine	N-(3-methylaminopropyl)iminobibenzyl|5-(-methylaminopropyl)iminodibenzyl|5-(gamma-Methylaminopropyl)iminodibenzyl|DMI|Dmthylimipramine|Desipramine|Norimipramine|3-(10,11-DIHYDRO-5H-dibenzo[b,F]azepin-5-yl)-N-methylpropan-1-amine|Desipramina|Monodemethylimipramine|Desipraminum|Desmethylimipramine|Desipramin	pms-desipramine - tab 100mg|de	DRUGBANK	DB01151	C18H22N2	small molecule	N06AA01	50-47-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYAFALTSJYZDH-UHFFFAOYSA-N
14271	112493	6609	-	SMPD1	ASM|ASMASE|NPD	9606	Homo sapiens	inhibitor	target	Erdreich-Epstein A (2005)	15705795	180383	1139	Desipramine	N-(3-methylaminopropyl)iminobibenzyl|5-(-methylaminopropyl)iminodibenzyl|5-(gamma-Methylaminopropyl)iminodibenzyl|DMI|Dmthylimipramine|Desipramine|Norimipramine|3-(10,11-DIHYDRO-5H-dibenzo[b,F]azepin-5-yl)-N-methylpropan-1-amine|Desipramina|Monodemethylimipramine|Desipraminum|Desmethylimipramine|Desipramin	pms-desipramine - tab 100mg|de	DRUGBANK	DB01151	C18H22N2	small molecule	N06AA01	50-47-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYAFALTSJYZDH-UHFFFAOYSA-N
14298	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14299	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14300	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Meyer JH (2002)	12185406	180401	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14301	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Kugaya A (2003)	12589396	180399	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14302	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Szabo Z (2004)	15787205	180398	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14303	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Stahl SM (2004)	15361919	180395	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14304	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Miller DK (2002)	12183670	180400	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14305	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Learned-Coughlin SM (2003)	14550679	180397	1144	Bupropion	Amfebutamone	bupropion hydrochloride (sr)|b	DRUGBANK	DB01156	C13H18ClNO	small molecule	A08AA62|N06AX12	34911-55-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SNPPWIUOZRMYNY-UHFFFAOYSA-N
14369	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Mansbach RS (1995)	7768269	180423	1149	Chloroprocaine	Chloroprocaine|Chlorprocaine|2-Chloroprocaine|Chloroprocain|Cloroprocaina|4-amino-2-Chlorobenzoic acid 2-(diethylamino)ethyl ester|Chloroprocainum	chloroprocaine hydrochloride|n	DRUGBANK	DB01161	C13H19ClN2O2	small molecule	N01BA04	133-16-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VDANGULDQQJODZ-UHFFFAOYSA-N
14370	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wilcox KM (1999)	10078990	180422	1149	Chloroprocaine	Chloroprocaine|Chlorprocaine|2-Chloroprocaine|Chloroprocain|Cloroprocaina|4-amino-2-Chlorobenzoic acid 2-(diethylamino)ethyl ester|Chloroprocainum	chloroprocaine hydrochloride|n	DRUGBANK	DB01161	C13H19ClN2O2	small molecule	N01BA04	133-16-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VDANGULDQQJODZ-UHFFFAOYSA-N
14371	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wilcox KM (2000)	11255924	180425	1149	Chloroprocaine	Chloroprocaine|Chlorprocaine|2-Chloroprocaine|Chloroprocain|Cloroprocaina|4-amino-2-Chlorobenzoic acid 2-(diethylamino)ethyl ester|Chloroprocainum	chloroprocaine hydrochloride|n	DRUGBANK	DB01161	C13H19ClN2O2	small molecule	N01BA04	133-16-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VDANGULDQQJODZ-UHFFFAOYSA-N
14372	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wilcox KM (2001)	11605081	180424	1149	Chloroprocaine	Chloroprocaine|Chlorprocaine|2-Chloroprocaine|Chloroprocain|Cloroprocaina|4-amino-2-Chlorobenzoic acid 2-(diethylamino)ethyl ester|Chloroprocainum	chloroprocaine hydrochloride|n	DRUGBANK	DB01161	C13H19ClN2O2	small molecule	N01BA04	133-16-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VDANGULDQQJODZ-UHFFFAOYSA-N
14491	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Bareggi SR (2007)	17916059	174434	1163	Escitalopram	Escitalopram Oxalate|Esertia|(+)-Citalopram|(S)-Citalopram|S-(+)-Citalopram|S(+)-Citalopram|Escitalopramum	escitalopram oxalate|escitalop	DRUGBANK	DB01175	C20H21FN2O	small molecule	N06AB10	128196-01-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WSEQXVZVJXJVFP-FQEVSTJZSA-N
15124	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	unknown	target	McGrogan BT (2008)	18068131	180741	1217	Paclitaxel	5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester|Taxol|Taxol A|Paclitaxel	abraxane|paclitaxel injection,	DRUGBANK	DB01229	C47H51NO14	small molecule	L01CD01	33069-62-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCINICONZNJXQF-MZXODVADSA-N
15289	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	agonist	target	Yang J (2002)	12297509	180798	1228	Epoprostenol	Flolan|Prostaglandin x|Prostacyclin|PGI2|(5Z,9alpha,11alpha,13e,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid|(5Z,13e)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate|Epoprostenol|Prostaglandin I2|Vasocyclin|PGX	epoprostenol sodium|flolan|car	DRUGBANK	DB01240	C20H32O5	small molecule	B01AC09	35121-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KAQKFAOMNZTLHT-OZUDYXHBSA-N
15290	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	agonist	target	Kobsar AL (2010)	20085435	180797	1228	Epoprostenol	Flolan|Prostaglandin x|Prostacyclin|PGI2|(5Z,9alpha,11alpha,13e,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid|(5Z,13e)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate|Epoprostenol|Prostaglandin I2|Vasocyclin|PGX	epoprostenol sodium|flolan|car	DRUGBANK	DB01240	C20H32O5	small molecule	B01AC09	35121-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KAQKFAOMNZTLHT-OZUDYXHBSA-N
15291	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	agonist	target	Cattaneo M (2007)	17155953	180796	1228	Epoprostenol	Flolan|Prostaglandin x|Prostacyclin|PGI2|(5Z,9alpha,11alpha,13e,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid|(5Z,13e)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate|Epoprostenol|Prostaglandin I2|Vasocyclin|PGX	epoprostenol sodium|flolan|car	DRUGBANK	DB01240	C20H32O5	small molecule	B01AC09	35121-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KAQKFAOMNZTLHT-OZUDYXHBSA-N
15377	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	unknown	target	McGrogan BT (2008)	18068131	180741	1236	Docetaxel	N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel|TXL|N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol|Docetaxel anhydrous	taxotere|docetaxel for injecti	DRUGBANK	DB01248	C43H53NO14	small molecule	L01CD02	114977-28-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
15418	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	multitarget	target	Imming P (2006)	17016423	171742	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15419	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	multitarget	target	Chen X (2002)	11752352	171740	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15420	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	multitarget	target	Overington JP (2006)	17139284	171741	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15421	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	multitarget	target	Lindauer M (2010)	20072833	180857	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15433	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Hamidovic A (2010)	20091113	180873	1243	Lisdexamfetamine	Lisdexamfetamine|NRP104|lisdexamfetamine dimesylate	vyvanse	DRUGBANK	DB01255	C15H25N3O	small molecule	N06BA12	608137-32-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOBHXZCDAVEXEY-JSGCOSHPSA-N
16147	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Fleckenstein AE (2007)	17209801	174169	1325	Ephedra	Chinese jointfir|Ma huang|Indian jointfir	stacker 2 nasal decongestant|e	DRUGBANK	DB01363	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16148	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Rothman RB (2003)	12954796	174149	1325	Ephedra	Chinese jointfir|Ma huang|Indian jointfir	stacker 2 nasal decongestant|e	DRUGBANK	DB01363	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16149	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Wee S (2004)	15189772	178697	1325	Ephedra	Chinese jointfir|Ma huang|Indian jointfir	stacker 2 nasal decongestant|e	DRUGBANK	DB01363	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16150	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Haughey HM (2000)	10773193	181167	1325	Ephedra	Chinese jointfir|Ma huang|Indian jointfir	stacker 2 nasal decongestant|e	DRUGBANK	DB01363	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16151	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Sulzer D (2005)	15955613	174152	1325	Ephedra	Chinese jointfir|Ma huang|Indian jointfir	stacker 2 nasal decongestant|e	DRUGBANK	DB01363	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16709	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Fleckenstein AE (2007)	17209801	174169	1390	MMDA	3-Methoxy-4,5-methylenedioxyphenylisopropylamine|5-Methoxy-3,4-methylenedioxyamphetamine|3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine|Amphetamine, 3,4-methylenedioxy-5-methoxy|(+-)-mmda|3-METHOXY-METHYLENEDIOXYAMPHETAMINE	-	DRUGBANK	DB01442	C11H15NO3	small molecule	-	13674-05-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQYUWUKDEVZFDB-UHFFFAOYSA-N
16710	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Haughey HM (2000)	10773193	181167	1390	MMDA	3-Methoxy-4,5-methylenedioxyphenylisopropylamine|5-Methoxy-3,4-methylenedioxyamphetamine|3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine|Amphetamine, 3,4-methylenedioxy-5-methoxy|(+-)-mmda|3-METHOXY-METHYLENEDIOXYAMPHETAMINE	-	DRUGBANK	DB01442	C11H15NO3	small molecule	-	13674-05-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQYUWUKDEVZFDB-UHFFFAOYSA-N
16711	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Sulzer D (2005)	15955613	174152	1390	MMDA	3-Methoxy-4,5-methylenedioxyphenylisopropylamine|5-Methoxy-3,4-methylenedioxyamphetamine|3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine|Amphetamine, 3,4-methylenedioxy-5-methoxy|(+-)-mmda|3-METHOXY-METHYLENEDIOXYAMPHETAMINE	-	DRUGBANK	DB01442	C11H15NO3	small molecule	-	13674-05-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQYUWUKDEVZFDB-UHFFFAOYSA-N
16746	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Fleckenstein AE (2007)	17209801	174169	1401	3,4-Methylenedioxymethamphetamine	Ecstasy|MDMA	-	DRUGBANK	DB01454	C11H15NO2	small molecule	-	42542-10-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHXWCVYOXRDMCX-UHFFFAOYSA-N
16747	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Hansen JP (2002)	11861820	181439	1401	3,4-Methylenedioxymethamphetamine	Ecstasy|MDMA	-	DRUGBANK	DB01454	C11H15NO2	small molecule	-	42542-10-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHXWCVYOXRDMCX-UHFFFAOYSA-N
16748	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Fitzgerald JL (1990)	1982265	181438	1401	3,4-Methylenedioxymethamphetamine	Ecstasy|MDMA	-	DRUGBANK	DB01454	C11H15NO2	small molecule	-	42542-10-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHXWCVYOXRDMCX-UHFFFAOYSA-N
16753	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Li SM (2006)	16478825	181442	1409	Fencamfamine	Fencamfamin|Fencamfamine|Fencamfaminum|Fencanfamina	-	DRUGBANK	DB01463	C15H21N	small molecule	N06BA06	1209-98-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IKFBPFGUINLYQI-UHFFFAOYSA-N
16754	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Seyfried CA (1983)	6136281	181441	1409	Fencamfamine	Fencamfamin|Fencamfamine|Fencamfaminum|Fencanfamina	-	DRUGBANK	DB01463	C15H21N	small molecule	N06BA06	1209-98-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IKFBPFGUINLYQI-UHFFFAOYSA-N
16768	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Fleckenstein AE (2007)	17209801	174169	1418	4-Methoxyamphetamine	Paramethoxyamphetamine|(2RS)-1-(4-methoxyphenyl)propan-2-amine|P-methoxyamfetamine|P-methoxyamphetamine|4-methoxyamfetamine|Formoterol fumarate related compound G|D,L-p-methoxyamphetamine	-	DRUGBANK	DB01472	C10H15NO	small molecule	-	64-13-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEGYEDYHPHMHGK-UHFFFAOYSA-N
16769	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Hansen JP (2002)	11861820	181439	1418	4-Methoxyamphetamine	Paramethoxyamphetamine|(2RS)-1-(4-methoxyphenyl)propan-2-amine|P-methoxyamfetamine|P-methoxyamphetamine|4-methoxyamfetamine|Formoterol fumarate related compound G|D,L-p-methoxyamphetamine	-	DRUGBANK	DB01472	C10H15NO	small molecule	-	64-13-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEGYEDYHPHMHGK-UHFFFAOYSA-N
16770	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Fitzgerald JL (1990)	1982265	181438	1418	4-Methoxyamphetamine	Paramethoxyamphetamine|(2RS)-1-(4-methoxyphenyl)propan-2-amine|P-methoxyamfetamine|P-methoxyamphetamine|4-methoxyamfetamine|Formoterol fumarate related compound G|D,L-p-methoxyamphetamine	-	DRUGBANK	DB01472	C10H15NO	small molecule	-	64-13-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEGYEDYHPHMHGK-UHFFFAOYSA-N
16771	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Daws LC (2000)	11041537	181445	1418	4-Methoxyamphetamine	Paramethoxyamphetamine|(2RS)-1-(4-methoxyphenyl)propan-2-amine|P-methoxyamfetamine|P-methoxyamphetamine|4-methoxyamfetamine|Formoterol fumarate related compound G|D,L-p-methoxyamphetamine	-	DRUGBANK	DB01472	C10H15NO	small molecule	-	64-13-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEGYEDYHPHMHGK-UHFFFAOYSA-N
17040	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Rothman RB (2009)	19244097	181529	1516	Dextroamphetamine	(+)-alpha-Methylphenethylamine|(S)-(+)-Amphetamine|(S)-1-Phenyl-2-aminopropane|dexamphetamine|(S)-(+)-beta-Phenylisopropylamine|Dextroamphetamine|(+)-alpha-Methylphenylethylamine|(+)-(S)-amphetamine|(+)-Amphetamine|d-amphetamine|Dexamfetamine|(S)-amphetamine|(S)-alpha-Methylbenzeneethanamine|(AlphaS)-alpha-methylbenzeneethanamine|(S)-1-Phenyl-2-propylamine	act amphetamine xr|dextroamphe	DRUGBANK	DB01576	C9H13N	small molecule	N06BA02	51-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-QMMMGPOBSA-N
17041	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Zhen J (2005)	16122767	181528	1516	Dextroamphetamine	(+)-alpha-Methylphenethylamine|(S)-(+)-Amphetamine|(S)-1-Phenyl-2-aminopropane|dexamphetamine|(S)-(+)-beta-Phenylisopropylamine|Dextroamphetamine|(+)-alpha-Methylphenylethylamine|(+)-(S)-amphetamine|(+)-Amphetamine|d-amphetamine|Dexamfetamine|(S)-amphetamine|(S)-alpha-Methylbenzeneethanamine|(AlphaS)-alpha-methylbenzeneethanamine|(S)-1-Phenyl-2-propylamine	act amphetamine xr|dextroamphe	DRUGBANK	DB01576	C9H13N	small molecule	N06BA02	51-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-QMMMGPOBSA-N
17042	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Kuczenski R (1995)	7869099	181530	1516	Dextroamphetamine	(+)-alpha-Methylphenethylamine|(S)-(+)-Amphetamine|(S)-1-Phenyl-2-aminopropane|dexamphetamine|(S)-(+)-beta-Phenylisopropylamine|Dextroamphetamine|(+)-alpha-Methylphenylethylamine|(+)-(S)-amphetamine|(+)-Amphetamine|d-amphetamine|Dexamfetamine|(S)-amphetamine|(S)-alpha-Methylbenzeneethanamine|(AlphaS)-alpha-methylbenzeneethanamine|(S)-1-Phenyl-2-propylamine	act amphetamine xr|dextroamphe	DRUGBANK	DB01576	C9H13N	small molecule	N06BA02	51-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-QMMMGPOBSA-N
17065	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Miller GM (2005)	15764732	174161	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17066	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Garcia BG (2005)	15795321	174163	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17067	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Lott DC (2005)	15602501	174162	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17068	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Kahlig KM (2005)	15728379	174165	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17069	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Fone KC (2005)	15661631	174164	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17070	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Escubedo E (2009)	19897077	181534	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17071	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Madras BK (2005)	15950014	174166	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17072	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	negative modulator	target	Fleckenstein AE (2007)	17209801	174169	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17467	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1569	Alpha-Phosphoribosylpyrophosphoric Acid	5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE|Ribofuranose, 5-phosphate 1-pyrophosphate|5-Phosphoribosyl 1-pyrophosphate|5-Phospho-alpha-D-ribose 1-diphosphate|Phosphoribosylpyrophosphate	-	DRUGBANK	DB01632	C5H13O14P3	small molecule	-	13270-65-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PQGCEDQWHSBAJP-TXICZTDVSA-N
17468	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1569	Alpha-Phosphoribosylpyrophosphoric Acid	5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE|Ribofuranose, 5-phosphate 1-pyrophosphate|5-Phosphoribosyl 1-pyrophosphate|5-Phospho-alpha-D-ribose 1-diphosphate|Phosphoribosylpyrophosphate	-	DRUGBANK	DB01632	C5H13O14P3	small molecule	-	13270-65-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PQGCEDQWHSBAJP-TXICZTDVSA-N
17469	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1569	Alpha-Phosphoribosylpyrophosphoric Acid	5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE|Ribofuranose, 5-phosphate 1-pyrophosphate|5-Phosphoribosyl 1-pyrophosphate|5-Phospho-alpha-D-ribose 1-diphosphate|Phosphoribosylpyrophosphate	-	DRUGBANK	DB01632	C5H13O14P3	small molecule	-	13270-65-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PQGCEDQWHSBAJP-TXICZTDVSA-N
17520	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1596	Adenosine-5'-Diphosphate Monothiophosphate	-	-	DRUGBANK	DB01660	C10H16N5O12P3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NLTUCYMLOPLUHL-FCIPNVEPSA-N
17521	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1596	Adenosine-5'-Diphosphate Monothiophosphate	-	-	DRUGBANK	DB01660	C10H16N5O12P3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NLTUCYMLOPLUHL-FCIPNVEPSA-N
17734	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1694	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	-	-	DRUGBANK	DB01761	C28H29F3N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QICPQLFMWYQJGX-SFHVURJKSA-N
17735	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1694	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	-	-	DRUGBANK	DB01761	C28H29F3N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QICPQLFMWYQJGX-SFHVURJKSA-N
17756	116446	11315	CTA-215D11.1	PARK7	DJ-1|DJ1|HEL-S-67p	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17757	116446	11315	CTA-215D11.1	PARK7	DJ-1|DJ1|HEL-S-67p	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17814	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
17815	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
17816	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
18043	110960	4905	-	NSF	SKD2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1829	1-Ethyl-Pyrrolidine-2,5-Dione	-	-	DRUGBANK	DB01902	C6H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GHAZCVNUKKZTLG-UHFFFAOYSA-N
18044	110960	4905	-	NSF	SKD2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1829	1-Ethyl-Pyrrolidine-2,5-Dione	-	-	DRUGBANK	DB01902	C6H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GHAZCVNUKKZTLG-UHFFFAOYSA-N
18045	110960	4905	-	NSF	SKD2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1829	1-Ethyl-Pyrrolidine-2,5-Dione	-	-	DRUGBANK	DB01902	C6H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GHAZCVNUKKZTLG-UHFFFAOYSA-N
18139	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1872	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	-	-	DRUGBANK	DB01948	C26H22Cl2F2N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXIYTVJEIXMAQF-UHFFFAOYSA-N
18140	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1872	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	-	-	DRUGBANK	DB01948	C26H22Cl2F2N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXIYTVJEIXMAQF-UHFFFAOYSA-N
18147	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18148	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18149	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18195	111639	5660	-	PSAP	GLBA|SAP1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1890	Di-Stearoyl-3-Sn-Phosphatidylethanolamine	-	-	DRUGBANK	DB01966	C41H82NO8P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNGJLRDBYCPGB-KDXMTYKHSA-N
18196	111639	5660	-	PSAP	GLBA|SAP1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1890	Di-Stearoyl-3-Sn-Phosphatidylethanolamine	-	-	DRUGBANK	DB01966	C41H82NO8P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNGJLRDBYCPGB-KDXMTYKHSA-N
18241	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1912	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	-	-	DRUGBANK	DB01988	C30H27N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WFSFNKVFXLIZIY-MHZLTWQESA-N
18242	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1912	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	-	-	DRUGBANK	DB01988	C30H27N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WFSFNKVFXLIZIY-MHZLTWQESA-N
18484	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1998	1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane	-	-	DRUGBANK	DB02078	C8H18O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFNKIDBQEZZDLK-UHFFFAOYSA-N
18544	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2028	2-Aminoethanimidic Acid	-	-	DRUGBANK	DB02108	C2H6N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AXQVKDQRBAXYBP-UHFFFAOYSA-N
18545	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2028	2-Aminoethanimidic Acid	-	-	DRUGBANK	DB02108	C2H6N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AXQVKDQRBAXYBP-UHFFFAOYSA-N
18614	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2067	3-Amino-4-Oxybenzyl-2-Butanone	-	-	DRUGBANK	DB02148	C11H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISLRAQPEXPIKDJ-NSHDSACASA-N
18615	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2067	3-Amino-4-Oxybenzyl-2-Butanone	-	-	DRUGBANK	DB02148	C11H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISLRAQPEXPIKDJ-NSHDSACASA-N
18616	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2067	3-Amino-4-Oxybenzyl-2-Butanone	-	-	DRUGBANK	DB02148	C11H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISLRAQPEXPIKDJ-NSHDSACASA-N
18697	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18698	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18699	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18742	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2128	S-Methylcysteine	-	-	DRUGBANK	DB02216	C4H9NO2S	small molecule	-	1187-84-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IDIDJDIHTAOVLG-VKHMYHEASA-N
18743	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2128	S-Methylcysteine	-	-	DRUGBANK	DB02216	C4H9NO2S	small molecule	-	1187-84-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IDIDJDIHTAOVLG-VKHMYHEASA-N
18744	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2128	S-Methylcysteine	-	-	DRUGBANK	DB02216	C4H9NO2S	small molecule	-	1187-84-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IDIDJDIHTAOVLG-VKHMYHEASA-N
18864	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18865	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18866	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18910	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2216	5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine	-	-	DRUGBANK	DB02309	C10H14N4O9P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCTLYFZHFGENCW-BZKDHIKHSA-O
18911	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2216	5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine	-	-	DRUGBANK	DB02309	C10H14N4O9P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCTLYFZHFGENCW-BZKDHIKHSA-O
18912	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2216	5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine	-	-	DRUGBANK	DB02309	C10H14N4O9P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCTLYFZHFGENCW-BZKDHIKHSA-O
19012	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19013	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19014	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19047	108913	2643	-	GCH1	DYT14|DYT5|DYT5a|GCH|GTP-CH-1|GTPCH1|HPABH4B	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2282	Guanine	-	-	DRUGBANK	DB02377	C5H4N5O	small molecule	-	73-40-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IOJBSLDWMHFRAL-UHFFFAOYSA-N
19302	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2381	Etheno-Nad	-	-	DRUGBANK	DB02483	C17H23N5O14P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LWAISUABIKYXTN-BVNNLCGGSA-N
19303	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2381	Etheno-Nad	-	-	DRUGBANK	DB02483	C17H23N5O14P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LWAISUABIKYXTN-BVNNLCGGSA-N
19520	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2492	N-Alpha-Acetyl-3,5-Diiodotyrosylglycine	-	-	DRUGBANK	DB02598	C13H14I2N2O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SXRYVFRVDCDPKH-JTQLQIEISA-N
19521	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2492	N-Alpha-Acetyl-3,5-Diiodotyrosylglycine	-	-	DRUGBANK	DB02598	C13H14I2N2O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SXRYVFRVDCDPKH-JTQLQIEISA-N
19522	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2492	N-Alpha-Acetyl-3,5-Diiodotyrosylglycine	-	-	DRUGBANK	DB02598	C13H14I2N2O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SXRYVFRVDCDPKH-JTQLQIEISA-N
19701	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2575	3-Methylphenylalanine	-	-	DRUGBANK	DB02685	C10H13NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JZRBSTONIYRNRI-VIFPVBQESA-N
19702	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2575	3-Methylphenylalanine	-	-	DRUGBANK	DB02685	C10H13NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JZRBSTONIYRNRI-VIFPVBQESA-N
19730	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2590	Nicotinamide	Nicotinic amide|Niacinamide	neogen dermalogy real fresh fo	DRUGBANK	DB02701	C6H6N2O	small molecule	A11HA01	98-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFPAKSUCGFBDDF-UHFFFAOYSA-N
19731	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2590	Nicotinamide	Nicotinic amide|Niacinamide	neogen dermalogy real fresh fo	DRUGBANK	DB02701	C6H6N2O	small molecule	A11HA01	98-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFPAKSUCGFBDDF-UHFFFAOYSA-N
20032	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2737	N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline	N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	-	DRUGBANK	DB02855	C18H31N3O6	small molecule	-	134448-10-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UDNIFTKCMDIXFC-ABHRYQDASA-N
20061	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20062	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20063	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20233	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20234	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20235	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20348	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2901	1h-Benoximidazole-2-Carboxylic Acid	-	-	DRUGBANK	DB03028	C8H5N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
20349	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2901	1h-Benoximidazole-2-Carboxylic Acid	-	-	DRUGBANK	DB03028	C8H5N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
20350	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2901	1h-Benoximidazole-2-Carboxylic Acid	-	-	DRUGBANK	DB03028	C8H5N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
20375	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
20376	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
20478	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2967	N-Aminoethylmorpholine	-	-	DRUGBANK	DB03096	C6H14N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RWIVICVCHVMHMU-UHFFFAOYSA-N
20479	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2967	N-Aminoethylmorpholine	-	-	DRUGBANK	DB03096	C6H14N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RWIVICVCHVMHMU-UHFFFAOYSA-N
20480	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2967	N-Aminoethylmorpholine	-	-	DRUGBANK	DB03096	C6H14N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RWIVICVCHVMHMU-UHFFFAOYSA-N
20500	108899	2629	-	GBA	GBA1|GCB|GLUC	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2977	Myo-Inositol	-	-	DRUGBANK	DB03106	C6H12O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDAISMWEOUEBRE-CDRYSYESSA-N
20501	108899	2629	-	GBA	GBA1|GCB|GLUC	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2977	Myo-Inositol	-	-	DRUGBANK	DB03106	C6H12O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDAISMWEOUEBRE-CDRYSYESSA-N
20505	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2981	2-Chlorophenol	-	-	DRUGBANK	DB03110	C6H5ClO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISPYQTSUDJAMAB-UHFFFAOYSA-N
20506	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2981	2-Chlorophenol	-	-	DRUGBANK	DB03110	C6H5ClO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISPYQTSUDJAMAB-UHFFFAOYSA-N
20525	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2993	5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid	-	-	DRUGBANK	DB03124	C20H20N2O9S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBAHOXPDTNUYCX-INIZCTEOSA-N
20526	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2993	5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid	-	-	DRUGBANK	DB03124	C20H20N2O9S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBAHOXPDTNUYCX-INIZCTEOSA-N
20527	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2993	5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid	-	-	DRUGBANK	DB03124	C20H20N2O9S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBAHOXPDTNUYCX-INIZCTEOSA-N
20679	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3021	3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol	-	-	DRUGBANK	DB03153	C5H4N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGCXIHWGXUQTCQ-UHFFFAOYSA-N
20680	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3021	3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol	-	-	DRUGBANK	DB03153	C5H4N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGCXIHWGXUQTCQ-UHFFFAOYSA-N
20681	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3021	3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol	-	-	DRUGBANK	DB03153	C5H4N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGCXIHWGXUQTCQ-UHFFFAOYSA-N
20794	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3095	Nicotinamide Mononucleotide	-	-	DRUGBANK	DB03227	C11H16N2O8P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DAYLJWODMCOQEW-WYOJIJJFSA-O
20795	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3095	Nicotinamide Mononucleotide	-	-	DRUGBANK	DB03227	C11H16N2O8P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DAYLJWODMCOQEW-WYOJIJJFSA-O
20983	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3193	2-Pyridinethiol	-	-	DRUGBANK	DB03329	C5H5NS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHMDPDGBKYUEMW-UHFFFAOYSA-N
20984	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3193	2-Pyridinethiol	-	-	DRUGBANK	DB03329	C5H5NS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHMDPDGBKYUEMW-UHFFFAOYSA-N
20985	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3193	2-Pyridinethiol	-	-	DRUGBANK	DB03329	C5H5NS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHMDPDGBKYUEMW-UHFFFAOYSA-N
21546	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3436	Diphenylacetic Acid	-	-	DRUGBANK	DB03588	C14H12O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PYHXGXCGESYPCW-UHFFFAOYSA-N
21547	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3436	Diphenylacetic Acid	-	-	DRUGBANK	DB03588	C14H12O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PYHXGXCGESYPCW-UHFFFAOYSA-N
21548	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3436	Diphenylacetic Acid	-	-	DRUGBANK	DB03588	C14H12O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PYHXGXCGESYPCW-UHFFFAOYSA-N
21817	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3575	Etheno-Nadp	-	-	DRUGBANK	DB03732	C17H24N5O17P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWEQFQACRLGUSH-MMKYUKOKSA-N
21818	107148	683	-	BST1	CD157	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3575	Etheno-Nadp	-	-	DRUGBANK	DB03732	C17H24N5O17P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWEQFQACRLGUSH-MMKYUKOKSA-N
21839	108899	2629	-	GBA	GBA1|GCB|GLUC	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3583	N-acetyl-alpha-D-glucosamine	-GlcNAc|2-(acetylamino)-2-deoxy-A-D-glucopyranose|-D-GlcNAc|N-acetyl--D-glucosamine|2-(acetylamino)-2-deoxy--D-glucopyranose	-	DRUGBANK	DB03740	C8H15NO6	small molecule	-	10036-64-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVRNDRQMDRJTHS-PVFLNQBWSA-N
21840	108899	2629	-	GBA	GBA1|GCB|GLUC	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3583	N-acetyl-alpha-D-glucosamine	-GlcNAc|2-(acetylamino)-2-deoxy-A-D-glucopyranose|-D-GlcNAc|N-acetyl--D-glucosamine|2-(acetylamino)-2-deoxy--D-glucopyranose	-	DRUGBANK	DB03740	C8H15NO6	small molecule	-	10036-64-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVRNDRQMDRJTHS-PVFLNQBWSA-N
22329	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3814	4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole	-	-	DRUGBANK	DB03980	C17H16FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFEYXQGDDCDXJK-UHFFFAOYSA-N
22597	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3951	Hexatantalum Dodecabromide	-	-	DRUGBANK	DB04119	Br12Ta6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJVLLWDZYINSDB-UHFFFAOYSA-N
22598	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3951	Hexatantalum Dodecabromide	-	-	DRUGBANK	DB04119	Br12Ta6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJVLLWDZYINSDB-UHFFFAOYSA-N
22599	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3951	Hexatantalum Dodecabromide	-	-	DRUGBANK	DB04119	Br12Ta6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJVLLWDZYINSDB-UHFFFAOYSA-N
22609	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3958	N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-2-Methyl-Butane	-	-	DRUGBANK	DB04126	C15H28N2O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBIWEWPGBHKYML-RYUDHWBXSA-N
22719	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3980	Threonine Derivative	-	-	DRUGBANK	DB04150	C15H18I2N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWMKRGDZEJLDDH-JPWUCKPDSA-N
22720	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3980	Threonine Derivative	-	-	DRUGBANK	DB04150	C15H18I2N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWMKRGDZEJLDDH-JPWUCKPDSA-N
22721	111101	5066	-	PAM	PAL|PHM	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3980	Threonine Derivative	-	-	DRUGBANK	DB04150	C15H18I2N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWMKRGDZEJLDDH-JPWUCKPDSA-N
23161	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23162	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23163	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23203	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4179	9-Deazaguanine	-	-	DRUGBANK	DB04356	C6H5N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
23204	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4179	9-Deazaguanine	-	-	DRUGBANK	DB04356	C6H5N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
23205	109488	3251	-	HPRT1	HGPRT|HPRT	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4179	9-Deazaguanine	-	-	DRUGBANK	DB04356	C6H5N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
23752	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4389	N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-	-	-	DRUGBANK	DB04579	C16H28N2O8	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TUAMLRIDHTYTCM-WKLONVCASA-N
23786	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4438	4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE	-	-	DRUGBANK	DB04632	C24H26FN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JHHBGNIRSUTQAS-UHFFFAOYSA-N
23910	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4599	Triazolopyridine	-	-	DRUGBANK	DB04797	C18H15FN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVCXRBARSPBVMC-UHFFFAOYSA-N
23930	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	unknown	target	Tatsumi M (1997)	9537821	174430	4623	Nomifensine	(+-)-nomifensin|Nomifensin|2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isoquinolinamine|(+)-nomiphensine|8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline|Nomifensina|Nomifensinum|8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisochinolin|8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline|(+-)-nomifensine|(+)-nomifensine|(R)-1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine	-	DRUGBANK	DB04821	C16H18N2	small molecule	N06AX04	24526-64-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXPANQJNYNUNES-UHFFFAOYSA-N
24129	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	unknown	target	Storey RF (2007)	17980251	182060	4702	AZD6140	-	-	DRUGBANK	DB04902	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24130	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	unknown	target	Springthorpe B (2007)	17827008	182046	4702	AZD6140	-	-	DRUGBANK	DB04902	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24209	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	unknown	target	Spencer TJ (2007)	17511972	182012	4741	Altropane	-	-	DRUGBANK	DB04947	C18H21FINO2	small molecule	-	180468-34-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTQLIPQFXVKRKJ-UNSMHXHVSA-N
24298	109368	3123	XXbac-BPG161M6.1	HLA-DRB1	DRB1|DRw10|HLA-DR1B|HLA-DRB|SS1	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	5037	Glatiramer Acetate	Copoylmer 1|COP-1|Copolymer-1	teva-glatiramer acetate|glatop	DRUGBANK	DB05259	C254H422N70O72	biologic	L03AX13	147245-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24299	109368	3123	XXbac-BPG161M6.1	HLA-DRB1	DRB1|DRw10|HLA-DR1B|HLA-DRB|SS1	9606	Homo sapiens	binder	target	Arnon R (2004)	15371592	181863	5037	Glatiramer Acetate	Copoylmer 1|COP-1|Copolymer-1	teva-glatiramer acetate|glatop	DRUGBANK	DB05259	C254H422N70O72	biologic	L03AX13	147245-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24391	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	binder	target	Tatsumi M (1997)	9537821	174430	5516	Mianserin	1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,F)pyrazino(1,2-a)azepine|Mianserine|Mianseryna|Mianserina|Mianserinum	-	DRUGBANK	DB06148	C18H20N2	small molecule	N06AX03	24219-97-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEQUQVLFIPOEMF-UHFFFAOYSA-N
24423	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	antagonist	target	Dovlatova NL (2008)	18485086	182077	5529	Prasugrel	Effient|Prasugrel	effient	DRUGBANK	DB06209	C20H20FNO3S	small molecule	B01AC22	150322-43-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DTGLZDAWLRGWQN-UHFFFAOYSA-N
24694	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Ding YS (1997)	9181638	181720	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24695	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24696	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Volkow ND (1999)	10025684	175966	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24697	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Izenwasser S (1999)	10414438	175967	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24698	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Wayment HK (1999)	10037500	175964	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24699	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Dresel SH (1999)	10199939	175965	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24700	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Markowitz JS (2008)	18480678	182076	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24701	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tilley MR (2008)	18698001	175963	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24702	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Davids E (2002)	11862378	181789	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24703	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Tatsumi M (1997)	9537821	174430	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24704	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Viggiano D (2004)	15303308	175968	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24705	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Volkow ND (1999)	10403500	175969	5583	Dexmethylphenidate	d-threo-methylphenidate|D-TMP|Dexmethylphenidate	dexmethylphenidate hydrochlori	DRUGBANK	DB06701	C14H19NO2	small molecule	N06BA11	40431-64-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUGOZIWVEXMGBE-CHWSQXEVSA-N
24780	108899	2629	-	GBA	GBA1|GCB|GLUC	9606	Homo sapiens	unknown	target	Pastores GM (2010)	20336596	182148	5602	Velaglucerase alfa	VPRIV|Imiglucerase	vpriv	DRUGBANK	DB06720	C2532H3850N672O711S16	biologic	A16AB10	884604-91-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24892	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5683	2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID	-	-	DRUGBANK	DB06862	C9H11NO5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UCQUNSCHVXCSCJ-UHFFFAOYSA-N
24912	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5702	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea	-	-	DRUGBANK	DB06882	C24H25N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HJWMLCDGRWWLAQ-UHFFFAOYSA-N
24963	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5759	N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide	-	-	DRUGBANK	DB06940	C19H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZZTMFGIGOADCFX-UHFFFAOYSA-N
25004	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5809	N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide	-	-	DRUGBANK	DB06991	C17H22N4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYOUIHFZUAKCEF-LLVKDONJSA-N
25149	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5956	5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one	-	-	DRUGBANK	DB07138	C19H9Cl2F2N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VEPKQEUBKLEPRA-UHFFFAOYSA-N
25170	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5978	N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE	-	-	DRUGBANK	DB07160	C12H19NO6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MZJYLQZZISBOTF-JBDRJPRFSA-N
25227	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6035	BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE	-	-	DRUGBANK	DB07219	C25H35N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OMQNYWZURFTFHE-MQBSTWLZSA-N
25230	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6039	METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE	-	-	DRUGBANK	DB07223	C19H31N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGWSRLSPWIEMLQ-YTFOTSKYSA-N
25231	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6040	N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE	-	-	DRUGBANK	DB07224	C15H24N2O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCCIQOJEDMDETP-QHZLYTNSSA-N
25232	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6041	N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE	-	-	DRUGBANK	DB07225	C18H30N2O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CFABOFMUPCWOPC-LHEWDLALSA-N
25241	107888	1508	-	CTSB	APPS|CPSB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6047	N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE	-	-	DRUGBANK	DB07231	C22H29N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MERYMLLGRCNRKE-HILJTLORSA-N
25314	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6123	N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide	-	-	DRUGBANK	DB07307	C26H23N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GQXMJOSCBRZMKE-UHFFFAOYSA-N
25475	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6270	4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE	-	-	DRUGBANK	DB07459	C19H16N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HVLSCZSVTCNAQX-UHFFFAOYSA-N
25559	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6352	5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOBUTYL-HEXANOIC ACID	-	-	DRUGBANK	DB07542	C16H31NO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	INCRGCAIRMMQQJ-ILXRZTDVSA-N
25614	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6413	4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB07607	C21H16IN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RXDZANYWRNIAOR-HHHXNRCGSA-N
25615	108192	1859	-	DYRK1A	DYRK|DYRK1|HP86|MNB|MNBH|MRD7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6414	N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide	-	-	DRUGBANK	DB07608	C24H22ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JDGOPNUGILVNJZ-IBGZPJMESA-N
25703	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6501	methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate	-	-	DRUGBANK	DB07696	C11H19NO5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QKEQESWFLCEUCV-QMMMGPOBSA-N
25833	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6609	N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide	-	-	DRUGBANK	DB07811	C21H21N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBVTVSINEVHYSY-UHFFFAOYSA-N
25847	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6626	4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE	-	-	DRUGBANK	DB07829	C14H10FN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BILJSHVAAVZERY-UHFFFAOYSA-N
25850	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6629	4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde	-	-	DRUGBANK	DB07832	C20H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VKQPTVJDZIILPG-UHFFFAOYSA-N
25851	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6630	N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide	-	-	DRUGBANK	DB07833	C24H18N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PMMLSQFPBFKLHH-UHFFFAOYSA-N
25852	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6631	N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide	-	-	DRUGBANK	DB07834	C21H21N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FOHZGCHKLPIBBX-UHFFFAOYSA-N
25853	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6632	N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide	-	-	DRUGBANK	DB07835	C22H24N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPSUAHGQHFKGG-UHFFFAOYSA-N
25880	107267	817	-	CAMK2D	CAMKD	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6650	[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE	-	-	DRUGBANK	DB07853	C22H19N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWMNWCNUTIFHRJ-JLPGSUDCSA-N
25966	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6737	3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide	-	-	DRUGBANK	DB07941	C22H19BrF2N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KCAJXIDMCNPGHZ-UHFFFAOYSA-N
25967	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6738	2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine	-	-	DRUGBANK	DB07942	C14H9F2N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJCHZVXSPFPKMX-UHFFFAOYSA-N
25968	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6739	2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol	-	-	DRUGBANK	DB07943	C20H20ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CATQHDWESBRRQA-UHFFFAOYSA-N
26060	107267	817	-	CAMK2D	CAMKD	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6832	Su6656	330161-87-0|NCGC00094279-01|B5839|HMS3648O08|NCGC00015981-09|N,N-DIMETHYL-2-OXO-3-((4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)METHYLENE)INDOLINE-5-SULFONAMIDE|2,3-DIHYDRO-N,N-DIMETHYL-2-OXO-3-[(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)METHYLENE]-1H-INDOLE-5-SULFONAMIDE|EX-A584|4071AH|AKOS015994571|MLS002153475|HMS2232C04|INSOLUTION&TRADE; SU6656|LOPAC0_000979|EU-0100979|NCGC00261664-01|S7774|Q7394936|NCGC00015981-03|1240328-42-0|SU 6656|SR-01000076237-6|HMS3263C19|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE|CCG-205059|SU-6656|SU6656|ES-0024|SU 6656, >=98% (HPLC)|SDCCGSBI-0050952.P003|NCGC00015981-04|NCGC00094279-02|LOPAC-S-9692|NCGC00015981-02|HSCI1_000124|SR-01000076237-1|HMS3229I04|SR-01000076237|CS-3943|GTPL6044|TOX21_500979|DB08039|(Z)-N,N-DIMETHYL-2-OXO-3-((4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)METHYLENE)INDOLINE-5-SULFONAMIDE|MFCD10565928|NCGC00015981-05|NCGC00015981-01|NCGC00015981-06|ZINC3875028|2-OXO-3-[1-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)-METH-(Z)-YLIDENE]-2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID DIMETHYLAMIDE|SMR001230828|S 9692|LP00979|BRD-K97354755-001-01-5|HY-B0789|BDBM50307127	-	DRUGBANK	DB08039	C19H21N3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LOGJQOUIVKBFGH-YBEGLDIGSA-N
26081	111308	5290	-	PIK3CA	CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|p110-alpha	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6852	(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE	-	-	DRUGBANK	DB08059	C23H24O8	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QDLHCMPXEPAAMD-QAIWCSMKSA-N
26089	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6857	N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA	-	-	DRUGBANK	DB08064	C20H22ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NTMADESEDXKNFZ-UHFFFAOYSA-N
26094	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6861	N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-	-	-	DRUGBANK	DB08068	C23H25ClFN3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQJVDUKATDECHF-ICSRJNTNSA-N
26119	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6884	3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE	-	-	DRUGBANK	DB08091	C26H25FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIUFYIOMUILESI-UHFFFAOYSA-N
26120	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6885	3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide	-	-	DRUGBANK	DB08092	C19H18FN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VMLSXFMXUNVCSK-UHFFFAOYSA-N
26121	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6886	3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE	-	-	DRUGBANK	DB08093	C16H14N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SZANYTFSQVBOBA-UHFFFAOYSA-N
26123	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6888	3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA	-	-	DRUGBANK	DB08095	C23H26ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZWYFTKPEHRQCCW-HNNXBMFYSA-N
26124	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6889	8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM	-	-	DRUGBANK	DB08096	C19H15ClF2N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZWKOUFZHPNIQSH-UHFFFAOYSA-N
26125	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6890	2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE	-	-	DRUGBANK	DB08097	C20H16F3N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGWSGDLIXOEZJG-UHFFFAOYSA-N
26230	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7004	1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE	-	-	DRUGBANK	DB08213	C20H20N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PFAYCUAUBOGVDX-AWEZNQCLSA-N
26246	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7019	[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID	-	-	DRUGBANK	DB08229	C20H23N3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JGMMFVVACJREFE-KRWDZBQOSA-N
26296	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7032	N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide	-	-	DRUGBANK	DB08242	C20H18N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYTBZXSFNNAVKU-UHFFFAOYSA-N
26304	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7040	4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID	-	-	DRUGBANK	DB08251	C17H14N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNRAPROKLOUIRA-AWEZNQCLSA-N
26324	108899	2629	-	GBA	GBA1|GCB|GLUC	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7071	(2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-NONYLPIPERIDINE-3,4,5-TRIOL	-	-	DRUGBANK	DB08283	C15H31NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FTSCEGKYKXESFF-LXTVHRRPSA-N
26396	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7134	N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide	-	-	DRUGBANK	DB08349	C24H21F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WMEYCLAVMZKZCS-UHFFFAOYSA-N
26398	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7136	N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide	-	-	DRUGBANK	DB08351	C25H29N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNEXDVSJIUQQRH-UHFFFAOYSA-N
26399	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7137	6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine	-	-	DRUGBANK	DB08352	C19H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQYJTHIYAQQJAB-UHFFFAOYSA-N
26440	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7179	2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE	-	-	DRUGBANK	DB08395	C22H18FN3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSOXFJURLPCSOO-UHFFFAOYSA-N
26468	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7205	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE	-	-	DRUGBANK	DB08423	C21H21FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QKZZJXRGCHXIAI-UHFFFAOYSA-N
26469	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7206	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE	-	-	DRUGBANK	DB08424	C19H18FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJDQETGUEUJVTB-HNNXBMFYSA-N
26541	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7276	(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate	-	-	DRUGBANK	DB08497	C19H14N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKBDSMREMMRFSI-INIZCTEOSA-N
26542	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7277	(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate	-	-	DRUGBANK	DB08498	C19H13ClN2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVSAMUIBGQSLDC-INIZCTEOSA-N
26543	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7278	N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide	-	-	DRUGBANK	DB08499	C21H18FN3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DQXBKUVWJSZHSI-UHFFFAOYSA-N
26570	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7299	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB08521	C21H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDMGBJANTYXAIV-HHHXNRCGSA-N
26572	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7300	4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE	-	-	DRUGBANK	DB08522	C18H16FN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ROKOFZNQCIIJMI-UHFFFAOYSA-N
26736	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7503	3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE	-	-	DRUGBANK	DB08730	C26H25FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CPFBZMFUCGHBAP-UHFFFAOYSA-N
26743	107889	1509	-	CTSD	CLN10|CPSD|HEL-S-130P	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7513	CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE	-	-	DRUGBANK	DB08740	C14H29NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KGYZGGUJJIVOQX-MELADBBJSA-N
27628	108913	2643	-	GCH1	DYT14|DYT5|DYT5a|GCH|GTP-CH-1|GTPCH1|HPABH4B	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	8061	Isopropyl Alcohol	-	labsco sterile alcohol prep pa	DRUGBANK	DB02325	C3H8O	small molecule	-	67-63-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KFZMGEQAYNKOFK-UHFFFAOYSA-N
27629	108913	2643	-	GCH1	DYT14|DYT5|DYT5a|GCH|GTP-CH-1|GTPCH1|HPABH4B	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	8061	Isopropyl Alcohol	-	labsco sterile alcohol prep pa	DRUGBANK	DB02325	C3H8O	small molecule	-	67-63-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KFZMGEQAYNKOFK-UHFFFAOYSA-N
27857	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	inhibitor	target	Loland CJ (2012)	22537794	196013	8077	Armodafinil	R-modafinil|()-2-[(R)-(diphenylmethyl)sulfinyl]acetamide	armodafinil|nuvigil	DRUGBANK	DB06413	C15H15NO2S	small molecule	N06BA13	112111-43-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFGHCGITMMYXAQ-LJQANCHMSA-N
27858	112422	6531	-	SLC6A3	DAT|DAT1|PKDYS	9606	Homo sapiens	antagonist	target	Loland CJ (2012)	22537794	196013	8077	Armodafinil	R-modafinil|()-2-[(R)-(diphenylmethyl)sulfinyl]acetamide	armodafinil|nuvigil	DRUGBANK	DB06413	C15H15NO2S	small molecule	N06BA13	112111-43-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFGHCGITMMYXAQ-LJQANCHMSA-N
27859	122309	64805	-	P2RY12	ADPG-R|BDPLT8|HORK3|P2T(AC)|P2Y(12)R|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999	9606	Homo sapiens	inhibitor	target	Gan XD (2015)	26402735	196030	7773	Cangrelor	[dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid	kengreal	DRUGBANK	DB06441	C17H25Cl2F3N5O12P3S2	small molecule	B01AC25	163706-06-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAEBIVWUMLRPSK-IDTAVKCVSA-N
28105	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	degradation	target	Chu TT (2016)	27105281	211375	8453	Bivalent ligand 37	Bivalent_ligand_37|TH006	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: TH006(VHL:HIF1a peptide --- Tau:Beta-tubulin peptide)	-
28151	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	degradation	target	Lu M (2018)	29407955	211357	8435	Bivalent ligand 58	Bivalent_ligand_58|Peptide 1	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: Peptide 1(Keap1:peptide Ac-LDPETGEYL-OH --- Tau:b-tubulin derived peptide)	-
28163	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPK14:foretinib)	-
28378	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Yang Y (2007)	17909057	211378	8340	PYR-41	PYR-41|Ethyl 4-{(4Z)-4-[(5-nitro-2-furyl)methylene]-3,5-dioxo-1-pyrazolidinyl}benzoate|Benzoic acid, 4-[(4Z)-4-[(5-nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]-, ethyl ester	-	CHEMSPIDER	4492747	C17H13N3O7	small molecule	-	418805-02-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ARGIPZKQJGFSGQ-LCYFTJDESA-N
28379	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	An H (2015)	28717502	211368	8341	ABP-A3	N-(3-Ethynylphenyl)-5'-O-sulfamoyladenosine|Adenosine, 5'-O-(aminosulfonyl)-N-(3-ethynylphenyl)-	-	CHEMSPIDER	57643654	C18H18N6O6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LZNFQRSVDZCPTR-SCFUHWHPSA-N
28380	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Xu GW (2010)	20075161	211377	8342	PYZD-4409	3,5-Pyrazolidinedione, 1-(3-chloro-4-fluorophenyl)-4-[(5-nitro-2-furanyl)methylene]-, (4E)-|(4E)-1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furyl)methylene]-3,5-pyrazolidinedione	-	CHEMSPIDER	29394292	C14H7ClFN3O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MSYMKEYWUWVZQY-RMKNXTFCSA-N
28513	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Barghout SH (2019)	29884901	214627	8580	TAK-243	V9GGV0YCDI|TAK-243|Sulfamic acid, [(1R,2R,3S,4R)-2,3-dihydroxy-4-[[2-[3-[(trifluoromethyl)thio]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]cyclopentyl]methyl ester|{(1R,2R,3S,4R)-2,3-Dihydroxy-4-[(2-{3-[(trifluoromethyl)sulfanyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)amino]cyclopentyl}methyl sulfamate	-	CHEMSPIDER	58828173	C19H20F3N5O5S2	small molecule	-	1450833-55-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KJDAGXLMHXUAGV-DGWLBADLSA-N
28567	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Koszela J (2018)	30097011	214402	8344	BAY 11-7082	3-(p-Tolylsulfonyl)acrylonitrile|3-(p-Toluenesulfonyl)acrylonitrile|3-((4-Methylphenyl)sulfonyl)-2-propenenitrile|2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-|(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile|BAY 11-7082|(2E)-3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile|2-Propenenitrile, 3-[(4-methylphenyl)sulfonyl]-, (2E)-|(2E)-3-[(4-Methylphenyl)sulfonyl]acrylonitrile|(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE	-	CHEMSPIDER	4510086	C10H9NO2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEWDSDBFRHVAP-KRXBUXKQSA-N
28745	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- GAK:TL13-87)	-
28896	111105	5071	KB-152G3.1	PARK2	AR-JP|LPRS2|PDJ|PRKN	9606	Homo sapiens	degradation	recruited e3 ligase	Schiedel M (2020)	32672888	223648	8566	Bivalent ligand 148	chloroalkylated SirReal 11|Bivalent_ligand_148	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	116593	22933	-	SIRT2	SIR2|SIR2L|SIR2L2	9606	Homo sapiens	target	Standardized BVL Name: chloroalkylated SirReal 11 (HaloTag-PRKN--- SIRT2:SirReal3)	-
28913	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donoghue C (2020)	32634680	223652	8548	Bivalent ligand 152	NR-7h|Bivalent_ligand_152	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NR-7h (CRBN:thalidomide --- MAPK14:PH-797804)	-
28927	109314	3064	-	HTT	HD|IT15	9606	Homo sapiens	degradation	target	Li Z (2020)	31690177	223658	8556	Bivalent ligand 158	ATTEC|Bivalent_ligand_158	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 binding moiety--linker--target binding moiety; target degraded via autophagic degradation	123565	81631	-	MAP1LC3B	ATG8F|LC3B|MAP1A/1BLC3|MAP1LC3B-a	9606	Homo sapiens	autophagy-targeting protein	Standardized BVL Name: ATTEC (MAP1LC3B --- mHTT)	-
28935	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	degradation	target	Silva MC (2019)	30907729	219824	8475	Bivalent ligand 162	QC-01x96175|Bivalent_ligand_162	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: QC-01175 (CRBN:pomalidomide --- MAPT:T807)	-
29957	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Ungermannova D (2012)	22274912	228688	9920	NSC 624206	N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride|Decylamine, N-(2-((p-chlorobenzyl)dithio)ethyl)-, hydrochloride|N-{2-[(4-Chlorobenzyl)disulfanyl]ethyl}-1-decanamine hydrochloride (1:1)|NSC 624206|1-Decanamine, N-[2-[[(4-chlorophenyl)methyl]dithio]ethyl]-, hydrochloride (1:1)|N-(2-((4-Chlorobenzyl)dithio)ethyl)-1-decanamine hydrochloride	-	CHEMSPIDER	320695	C19H33Cl2NS2	small molecule	-	13116-77-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JQHUAYXPNPTQRO-UHFFFAOYSA-N
30111	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Kargbo RB (2020)	32550983	228713	9762	Bivalent ligand 198	compound 1|Bivalent_ligand_198	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 1 (VHL:VHL-1 --- SNCA:BTA-1)	-
30113	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Kargbo RB (2020)	32550983	228713	9761	Bivalent ligand 199	compound 4|Bivalent_ligand_199	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 4 (VHL:VHL-1 --- SNCA:BTA-1)	-
30115	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Kargbo RB (2020)	32550983	228713	9787	Bivalent ligand 200	compound 5|Bivalent_ligand_200	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 5 (VHL:VHL-1 --- SNCA:BTA-1)	-
30117	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Kargbo RB (2020)	32550983	228713	9786	Bivalent ligand 201	compound 7|Bivalent_ligand_201	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 7 (VHL:VHL-1 --- SNCA:SNCA ligand)	-
30119	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Kargbo RB (2020)	32550983	228713	9785	Bivalent ligand 202	compound 34|Bivalent_ligand_202	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 34 (VHL:VHL-1 --- SNCA:SNCA ligand)	-
30121	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Kargbo RB (2020)	32550983	228713	9784	Bivalent ligand 203	compound 30|Bivalent_ligand_203	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 30 (CRBN:thalidomide --- SNCA:SNCA ligand)	-
30596	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- FYN:TAE684)	-
30598	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- GAK:TAE684)	-
30612	125700	120892	-	LRRK2	AURA17|DARDARIN|PARK8|RIPK7|ROCO2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- LRRK2:TAE684)	-
30766	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- GAK:TAE684)	-
30862	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- FYN:GNF-7)	-
30864	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- GAK:GNF-7)	-
30874	125700	120892	-	LRRK2	AURA17|DARDARIN|PARK8|RIPK7|ROCO2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LRRK2:GNF-7)	-
30894	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
30976	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- GAK:TAE)	-
31058	110825	4750	-	NEK1	NY-REN-55|SRPS2|SRPS2A|SRTD6	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- NEK1:Ceritinib)	-
31114	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- FYN:GNF-7)	-
31116	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- GAK:GNF-7)	-
31130	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK14:GNF-7)	-
31248	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- FYN:Ponatinib)	-
31250	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- GAK:Ponatinib)	-
31268	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAPK14:Ponatinib)	-
31306	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- GAK:GNF-7)	-
31322	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK14:GNF-7)	-
31366	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- GAK:GNF-7)	-
31380	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK14:GNF-7)	-
31538	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0680 (VHL:VHL-1--- GAK:Thienopyrimidines)	-
31600	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- GAK:TAE684)	-
31636	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- GAK:Thienopyrimidines)	-
31666	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10070	Bivalent Ligand 280	DD-02-198|Bivalent_Ligand_280	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-02-198 (VHL:VH032---MAPK14:AZ628)	-
31770	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- FYN:PP58 (kinobeads) 212391-57-6)	-
31772	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- GAK:PP58 (kinobeads) 212391-57-6)	-
31778	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- MAPK14:PP58 (kinobeads) 212391-57-6)	-
31840	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- GAK:GNF-7)	-
31854	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
31912	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- GAK:MRT68921)	-
32106	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- GAK:MRT68921)	-
32166	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- FYN:TX1-85-1)	-
32184	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JWG-123 (VHL:VHL-1--- GAK:TG101209)	-
32212	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- FYN:TX1-85-1)	-
32230	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- GAK:Quizartinib)	-
32238	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- MAPK14:Quizartinib)	-
32396	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- FYN:Ibrutinib)	-
32434	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-178 (CRBN:pomalidomide--- MAPK14:Ponatininb)	-
32470	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9995	Bivalent Ligand 317	JWG-118|Bivalent_Ligand_317	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JWG-118 (CRBN:Thalidomide--- GAK:TG101209)	-
32538	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10142	Bivalent Ligand 328	JWG-122|Bivalent_Ligand_328	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JWG-122 (VHL:VHL-1--- GAK:TG101209)	-
32650	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	degradation	target	Silva MC (2022)	35317195	235160	10028	Bivalent Ligand 370	QC-01-175|Bivalent_Ligand_370	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: QC-01-175 (CRBN:pomalidomide---MAPT:T807)	-
32652	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	degradation	target	Silva MC (2022)	35317195	235160	10027	Bivalent Ligand 371	FMF-06-049|Bivalent_Ligand_371	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-049 (CRBN:pomalidomide---MAPT:T807)	-
32654	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	degradation	target	Silva MC (2022)	35317195	235160	10026	Bivalent Ligand 372	FMF-06-038|Bivalent_Ligand_372	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-038 (CRBN:pomalidomide---MAPT:T807)	-
32848	111308	5290	-	PIK3CA	CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|p110-alpha	9606	Homo sapiens	degradation	target	Wang H (2022)	35344835	239591	10059	Bivalent ligand 421	HL-8|Bivalent_ligand_421	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HL-8(VHL:VHL ligand --- PIK3CA:compound 15a)	-
33161	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Raymonda MH (2022)	34871905	239614	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: p38 MAPK inhibitor; viral inhibition mechanism undetermined	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
33449	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10330	4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole	SW218141-2|4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-5-(4-PYRIDYL)-1H-IMIDAZOLE;SB-203580|SR-01000597367|J-008891|HMS3267B07|BCP01763|CDMGBJANTYXAIV-UHFFFAOYSA-N|RWJ-64809|US9187470, 104 (SB203580)|4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-5-(4-PYRIDYL)-1H-IMIDAZOLE|PYRIDINE, 4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-YL]- & Z-100|4-[5-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-3H-IMIDAZOL-4-YL]PYRIDINE|OU13V1EYWQ|SB 203580|AKOS015994568|HMS1792H05|AM81234|4-{4-(4-FLUOROPHENYL)-2-[4-(METHANESULFINYL)PHENYL]-1H-IMIDAZOL-5-YL}PYRIDINE|PB-203580|UNII-OU13V1EYWQ|HMS3403H05|RAC-4-(5-(4-FLUOROPHENYL)-2-(4-((R)- METHANESULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)PYRIDINE|NCGC00025035-04|PB203580|HMS3676M17|CCG-206878|BIO1_000745|4-{4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-5-YL}PYRIDINE|HB1302|NCGC00025035-05|4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFONYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE|4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE|S1076|F0864|HMS3244I16|BIO1_000256|NCGC00025035-02|A15256|NCGC00025035-01|J-513573|RWJ 64809|K00038|PYRIDINE, 4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-5-YL)-|ES-0013|NSC-755772|PYRIDINE, 4-[4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-5-YL]-|TOCRIS-1402|4-(5-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)PYRIDINE|4-[4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-1H-IMIDAZOL-5-YL]PYRIDINE|PYRIDINE, 4-(5-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)-|SB203580|4-[4-(4-FLUOROPHENYL)-2-(4-METHANESULFINYLPHENYL)-1H-IMIDAZOL-5-YL]PYRIDINE|BIRB-203580|4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE|HMS3295M11|NSC755772|BRD-A37704979-003-01-2|SB 203580, SOLID, >=98% (HPLC)|SB 203580 & Z-100|SR-01000597367-1|CBIOL_001970|ADEZMAPIMOD|NCGC00381704-12|PYRIDINE, 4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-YL]-|KINOME_2521|4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE|ADEZMAPIMOD [INN]|SMR004701767|1PME|TOCRIS-1202|SB16633|MLS006010840|HMS3244I15|4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)-PHENYL)-1H-IMIDAZOL-5-YL)PYRIDINE|AC-32046|BIO1_001234|4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)1H-IMIDAZOLE|EX-A134|GTPL5269|NCGC00025035-03|SB-203580|DTXSID2040577|CS-0140|152121-47-6|PB 203580|FT-0674525|BIRB203580|4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-5-YL)PYRIDINE|HMS3412M17|CID_176155|F17411|HMS3654M15|SB 203580 - CAS 152121-47-6|SB203580,RWJ 64809,PB 203580|BRD-A37704979-001-02-4|Q7389023|C21H16FN3OS|BCPP000074|RWJ64809|HMS3244J15|MFCD00922198|HMS1990H05|HY-10256|AKOS005145971|HMS3229O04|BSPBIO_001104	-	PUBCHEM	176155	C21H16FN3OS	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human p38 inhibitor;  antiviral activity against SARS-CoV-2 in ACE2-A549 cells	CDMGBJANTYXAIV-UHFFFAOYSA-N
33454	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10333	Ralimetinib	5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL)-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO(4,5-B)PYRIDIN-2-YLAMINE|UNII-73I34XW4HD|SB16635|NCGC00346537-01|XPPBBJCBDOEXDN-UHFFFAOYSA-N|NSC-766820|LSN-2322600 FREE BASE|BCPP000180|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|RALIMETINIB [USAN]|Q27088512|862505-00-8|RALIMETINIB [INN]|LY 2228820|RALIMETINIB [USAN:INN]|LY2228820 FREE BASE|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|862505-00-8 (FREE BASE)|RALIMETINIB [WHO-DD]|NCGC00346537-05|LY22288220|DB11787|AKOS027282678|HMS3674E21|3H-IMIDAZO(4,5-B)PYRIDIN-2-AMINE, 5-(2-(1,1-DIMETHYLETHYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-|GTPL7959|3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE,5-[2-(1,1-DIMETHYLETHYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)-|CS-0008496|D10658|RALIMETINIB (USAN/INN)|(5P)-5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|DTXSID00235456|HY-13241A|BCP02033|LY-2228820|73I34XW4HD|RALIMETINIB ( LY2228820)|NSC766820|NCGC00346537-03|E98891|RALIMETINIB|YXT|5-(2-(TERT-BUTYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|LSN2322600 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-YLAMINE|LY-2228820 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUOROPHENYL)-3H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[5,4-B]PYRIDIN-2-AMINE|NSC785335|NSC-785335|BCP9000871|FT-0727743	-	PUBCHEM	11539025	C24H29FN6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human MAPK11/MAPK14 inhibitor;  antiviral activity against SARS-CoV-2 in Vero-E6 cells	XPPBBJCBDOEXDN-UHFFFAOYSA-N
33456	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10335	p38alpha Inhibitor 1	5-(2,4-DIFLUOROPHENOXY)-N-(2-(DIMETHYLAMINO)ETHYL)-1-ISOBUTYL-1H-INDAZOLE-6-CARBOXAMIDE|ARRY-797|1034189-82-6|CS-0085271|P38?? INHIBITOR 1|EX-A3148|ARRY-371797|ARRY371797|1036404-17-7|COMPOUND 7 [PMID: 19950901]|ARRY797|P38A INHIBITOR 1|P38 ALPHA INHIBITOR 1|P38-ALPHA- INHIBITOR 1|-(2,4-DIFLUOROPHENOXY)-N-[2-(DIMETHYLAMINO)ETHYL]-1-(2-METHYLPROPYL)INDAZOLE-6-CARBOXAMIDE|P38ALPHA INHIBITOR 1|HY-114423|AKOS040733949|ARRY-797; ARRY-371797|P38|A INHIBITOR 1|MS-27245|5-(2,4-DIFLUOROPHENOXY)-N-[2-(DIMETHYLAMINO)ETHYL]-1-(2-METHYLPROPYL)INDAZOLE-6-CARBOXAMIDE|GTPL11095	-	PUBCHEM	46883775	C22H26F2N4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human MAPK14 inhibitor;  antiviral activity against SARS-CoV-2 in ACE2-A549 cells	IFGWYHGYNVGVRB-UHFFFAOYSA-N
33630	125700	120892	-	LRRK2	AURA17|DARDARIN|PARK8|RIPK7|ROCO2	9606	Homo sapiens	degradation	target	Liu X (2022)	36007011	256627	10783	Bivalent ligand 554	XL01126|bivalent_ligand_554	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: XL01126 (VHL:VH101 --- LRRK2:HG-10-102-01)	-
33634	109314	3064	-	HTT	HD|IT15	9606	Homo sapiens	degradation	target	Mei L (2023)	37424101	254385	10785	Bivalent ligand 556	QBP-LIR|bivalent_ligand_556	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 binding moiety--linker--target binding moiety; target degraded via autophagic degradation	123565	81631	-	MAP1LC3B	ATG8F|LC3B|MAP1A/1BLC3|MAP1LC3B-a	9606	Homo sapiens	autophagy-targeting protein	Standardized BVL Name: QBP-LIR (MAP1LC3B:LIR --- HTT65Q:QBP)	-
33636	109314	3064	-	HTT	HD|IT15	9606	Homo sapiens	degradation	target	Mei L (2023)	37424101	254385	10786	Bivalent ligand 557	QBP-ABP|bivalent_ligand_557	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 binding moiety--linker--target binding moiety; target degraded via autophagic degradation	120375	55054	hCG_1817841	ATG16L1	APG16L|ATG16A|ATG16L|IBD10|WDR30	9606	Homo sapiens	autophagy-targeting protein	Standardized BVL Name: QBP-ABP (ATG16L1:ABP --- HTT65Q:QBP)	-
33714	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	degradation	target	Wang W (2021)	33859747	254525	10816	Bivalent ligand 587	C004019|bivalent_ligand_587	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: C004019 (VHL:VH032 --- tau:triazole-based tau binder moiety)	-
34126	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Wen T (2023)	37298935	256429	10979	Bivalent ligand 758	Compound 5|bivalent_ligand_758	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 5 (cIAP1 :bestatin --- SNCA:sery384)	-
34136	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	degradation	target	Tong Y (2023)	37267712	256432	10983	Bivalent ligand 762	Compound 2b|bivalent_ligand_762	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 2b (CRBN:pomalidomide --- SNCA:sery308)	-
34152	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Zhang Y (2023)	37196766	256442	10989	Bivalent ligand 768	SIAIS352008|bivalent_ligand_768	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS352008 (CRBN:lenalidomide --- GAK:brigatinib)	-
34158	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	degradation	target	Zhang Y (2023)	37196766	256442	10990	Bivalent ligand 769	SIAIS262039|bivalent_ligand_769	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS262039 (CRBN:lenalidomide --- GAK:brigatinib)	-
34228	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Son SH (2023)	36968534	256474	11017	Bivalent ligand 796	PRZ-18002|bivalent_ligand_796	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PRZ-18002 (CRBN:pomalidomide --- MAPK14:p-p38 ligand)	-
34262	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Cubillos-Rojas M (2023)	36765568	256520	11032	Bivalent ligand 810	NR-11c|bivalent_ligand_810	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NR-11c (VHL:VHL ligand --- MAPK14:PH-797804)	-
