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    REBASE, The Restriction Enzyme Database   http://rebase.neb.com
    Copyright (c)  Dr. Richard J. Roberts, 1999.   All rights reserved.
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                               R E B A S E

       The Restriction Enzyme Database is a collection of information about
restriction enzymes, methylases, the microorganisms from which they have been
isolated, recognition sequences, cleavage sites, methylation specificity, the
commercial availability of the enzymes, and references - both published and
unpublished observations (dating back to 1952).

       REBASE is updated daily.  Each month, a set of REBASE data files are
released publically and distributed to the scientific community at no charge
via a regular monthly emailing list, and made available via ftp and the web
(http://rebase.neb.com).  Many of these data files have been designed
specifically for use with a variety of software packages, such as GCG and
IntelliGenetics.  As REBASE expands, an ever-growing number of new data files
are being provided.  Requests for additional formats are welcome, as we are
prepared to support each major sequence analysis package.


                                   Dr. Richard J. Roberts
                                   New England BioLabs
                                   32 Tozer Road
                                   Beverly, Massachusetts 01915 U.S.A.

                                   phone:        (978) 927-5054
                                   fax:          (978) 921-1527
                                   email:        roberts@neb.com


        Latest Review:    Nucleic Acids Research 27: 312-313, 1999.